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Chalkley Robert J - - 2013
To address problems with estimating the reliability of proteomic search engine results from mass spectrometry fragmentation data the use of target-decoy database searching has become the de facto approach for estimating a false discovery rate. Several articles have been written about the effects of different ways of creating the decoy ...
Wang Pengcheng - - 2013
Reactive oxygen species (ROS) have been characterized as both important signaling molecules and universal stressors that mediate many developmental and physiological responses. So far, details of the transcriptional mechanism of ROS-responsive genes are still largely unknown. In the study reported herein, we identified seven potential ROS-responsive cis-acting elements (ROSEs) from ...
Li Baohai - - 2013
Plastid retrograde signaling (chloroplast to nucleus) has been proposed to play an important role in the acclimation of plant function to environmental stress. Although several pathways and molecular components, as well as some signals, have been identified in recent years, our understanding of the communication between plastid and nucleus under ...
De Tullio Mario - - 2013
The functional role of ascorbate oxidase (AO; EC 1.10.3.3) has never been fully explained so far, due to the difficulties in understanding the presence of an enzyme specifically oxidizing ascorbate with no obvious advantage, and the apparent disadvantage of lowering plant stress resistance as a consequence of ascorbate consumption. Here ...
Yavuz Oguzhan - - 2013
In this study, 70 Wistar rats were randomly divided into seven equal groups (six experimental and one control), which consisted of animals belonging to both sexes. Different combinations of insecticides were administered daily to the experimental groups (group 1: cypermethrin + piperonyl butoxide (PBO); group 2: alphacypermethrin + PBO; group ...
Hartman Marthinus J - - 2013
OBJECTIVE: To describe laparoscopic ovariectomy and salpingectomy in the African lioness (Panthera leo). STUDY DESIGN: Descriptive clinical study. ANIMALS: Female lions (n = 16). METHODS: Lionesses were randomly divided into 2 groups: O = ovariectomy (n = 8) and S = salpingectomy (n = 8) for laparoscopic surgery. Two Veress needle placement techniques were used. ...
Mathialagan Ramyaa - - 2013
Homobimetallic dicobalt complexes featuring metal centers in different coordination environments have been synthesized, and their multielectron redox chemistry has been investigated. Treatment of CoX(2) with MesNKP(i)Pr(2) leads to self-assembly of [(THF)Co(MesNP(i)Pr(2))(2)(μ-X)CoX] [X = Cl (1), I (2)], with one Co center bound to two amide donors and the other bound ...
Donnelley Martin - - 2013
Abstract Background: The manner in which fluid instillations into mouse nose and lung distribute through the airways is poorly understood. Many agents are delivered in this way for testing as therapeutics, or as challenges designed to establish infections or create systemic drug delivery effects. These agents are delivered into mouse ...
De Sio Luciano - - 2013
An empty polymeric structure has been realized by combining a high precision level optical holographic setup and a selective microfluidic etching process. The distinctive features of the realized periodic microstructure enabled aligning several kinds of Liquid Crystal (LC) compounds, without the need of any kind of surface chemistry or functionalization. ...
Moison Céline - - 2013
Retinoic acid receptor β 2 (RARβ2) is a tumor suppressor gene whose loss of expression is recurrent in prostate cancers. Here we studied the epigenetic mechanisms leading to its stable silencing. First, we characterized all RARβ isoforms in 6 human tumor cell lines (prostate DU145, LNCaP, PC3, lung A549, breast ...
Abou-Zied Osama K - - 2013
Human serum albumin (HSA) is the most abundant protein in blood plasma. It has high relevance for the lipid metabolism and its ability to bind a large variety of natural and pharmaceutical compounds makes it a crucial determinant of drug pharmaco-kinetics and -dynamics. The drug binding properties of HSA can ...
Patel Bimal A - - 2013
Lumbar puncture (LP) is associated with complications that include post-LP orthostatic headache, local bleeding, and subdural hematoma. We report a unique case of a spontaneous frontal epidural hematoma following a therapeutic lumbar puncture in a patient with a history of idiopathic intracranial hypertension. This case highlights the importance of symptomatology ...
Lupini Antonio - - 2013
Coumarin effects on gravitropic responses of Arabidopsis thaliana roots were here evaluated. Coumarin alone did not cause any alteration on gravitropic response showing a behavior similar to control plants. In contrast, TIBA and NPA, two auxin transport inhibitors, strongly modified root gravitropic responses. The addition of coumarin to the medium ...
Liu Bing - - 2013
Plant innate immunity relies on successful detection of trespassing pathogens through recognizing their microbe-associated molecular patterns (MAMPs) by pattern recognition receptors (PRRs) at the cell surface. We recently reported two rice lysin motif (LysM)-containing proteins, OsLYP4 and OsLYP6, as dual functional PRRs sensing bacterial peptidoglycan (PGN) and fungal chitin. Here ...
Wang Kai - - 2013
Fine count two-ply yarn supercapacitors are constructed from carbon nanotube yarns and polyaniline nanowires. The thread-like supercapacitors possess excellent electrochemical capacity and are very strong and flexible. When being woven or knitted into wearable electronic devices, alone or in combination with conventional textile yarns, the two-ply yarn supercapacitors can be ...
Franks Mark - - 2013
Five-coordinate Zn(II), Ni(II), and Cu(II) complexes containing pentadentate N(3)O(2) Schiff base ligands [1A](2-) and [1B](2-) have been synthesized and characterized. X-ray crystallographic studies reveal five coordinate structures in which each metal ion is bound by two imine N-donors, two phenolate O-donors, and a single amine N-donor. Electron paramagnetic resonance (EPR) ...
Avci Bahattin - - 2013
This study is intended to examine the effects of administration of asymmetric dimethylarginine (ADMA) on the levels of tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6) and IL-10. A total of 30 Wistar adult albino rats were used. Group I was administrated (n = 10) with 1 mg/kg/day of ADMA, group II ...
Wang Liang - - 2013
Digital ion trap (DIT) and rectilinear ion trap (RIT) have been proven to be very useful technology in past years. In this work, the digital ion trap technology was combined with the ceramic-based rectilinear ion trap (cRIT) system. Rectangular waveform was used for ion trapping. A dipolar excitation waveform which ...
von Davier Matthias - - 2013
The 'deterministic-input noisy-AND' (DINA) model is one of the more frequently applied diagnostic classification models for binary observed responses and binary latent variables. The purpose of this paper is to show that the model is equivalent to a special case of a more general compensatory family of diagnostic models. Two ...
UrbaƄczyk Mateusz - - 2013
Pulsed Gradient Spin Echo (PGSE) is a well-known NMR technique for determination of diffusion coefficients. Various signal processing techniques have been introduced to solve the task, which is especially challenging when the decay is multi-exponential with unknown number of components. Here, we introduce a new method for processing of such ...
Islam Mohammad Mafijul - - 2013
ABSTRACT: BACKGROUND: Malnutrition is one of the principal causes of child mortality in developing countries including Bangladesh. According to our knowledge, most of the available studies, that addressed the issue of malnutrition among under-five children, considered the categorical (dichotomous/polychotomous) outcome variables and applied logistic regression (binary/multinomial) to find their predictors. ...
Foxe David G - - 2013
Logopenic progressive aphasia (LPA) is a form of primary progressive aphasia (PPA) characterized by hesitant speech with marked impairment in naming and repetition. LPA is associated with brain atrophy in the left temporal and inferior parietal cortices and is predominantly associated with Alzheimer's disease (AD) pathology. In contrast to LPA, ...
Ganova-Raeva Lilia M - - 2013
The molecular detection of transmission of rapidly mutating pathogens such as hepatitis C virus (HCV) is commonly achieved by assessing the genetic relatedness of strains among infected patients. We describe the development of a novel mass spectrometry (MS)-based approach to identification of HCV transmissions. MS was used to detect products ...
Shi Ting-Yan - - 2013
TNFAIP8 is an anti-apoptotic and pro-oncogenic signaling molecule involved in the process of immunity, carcinogenesis and tumor progression. Single nucleotide polymorphisms (SNPs) at microRNA binding sites may change mRNA target gene function, thus leading to cancer susceptibility and tumor progression. In this study of 1,584 cervical cancer cases and 1,394 ...
Nakai Yusuke - - 2013
VOZ (vascular plant one zinc-finger protein) is a plant specific one-zinc finger type transcriptional activator, which is highly conserved through land plant evolution. We have previously shown that loss-of-function mutation in VOZ1 and VOZ2 showed increased cold and drought stress tolerances whereas decreased biotic stress resistance in Arabidopsis. Here, we ...
Strazielle Nathalie - - 2013
The brain develops and functions within a strictly controlled environment resulting from the coordinated action of different cellular interfaces located between the blood and the extracellular fluids of the brain, which includes the interstitial fluid and the cerebrospinal fluid (CSF). As a correlate, the delivery of pharmacologically active molecules and ...
Ruiz-Alcocer Javier - - 2013
BACKGROUND: The aim of this study was to analyse the visual quality of the AcrySof IQ SN60WF(®) intraocular lens (IOL) when combined with different corneal profiles. METHODS: Ten eyes of 10 participants with no prior history of refractive or cataract surgery were evaluated. An adaptive optics visual simulator was used ...
Hulstaert Frank - - 2013
Objectives: We studied the cost-effectiveness of tenofovir and entecavir in e antigen positive (CHBe+) and negative (CHBe-) chronic hepatitis B. Methods: Using a multicenter survey including 544 patients we measured patient quality of life and attributable costs by clinical disease stage. Natural disease progression was studied in 278 patients in ...
Camp Christopher L - - 2013
Patellar resurfacing is a commonly performed procedure during total knee arthroplasty (TKA). Common goals of patellar resurfacing are to obtain a stable, functional, patellofemoral joint with minimal pain. This is typically accomplished by resecting the patella in a symmetric fashion while attempting to restore native patellar thickness. Several cutting guides ...
Currao Rachael L - - 2013
OBJECTIVE: To evaluate the efficacy and safety of a percutaneously controlled urethral hydraulic occluder (HO) device for the treatment of refractory urinary incontinence (RUI) in female dogs with various urogenital anomalies. STUDY DESIGN: Case series. ANIMALS: Female dogs with RUI (n = 18). METHODS: Retrospective evaluation of dogs after a ...
Schulz Melanie - - 2013
A comprehensive quantitative analysis of changes in protein phosphorylation preceding or accompanying transcriptional activation by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in 5L rat hepatoma cells was performed using the SILAC approach. Following exposure of the cells to DMSO or 1 nM TCDD for 0.5 to 2 h, 5648 phosphorylated peptides corresponding to 2156 ...
Li Liming - - 2013
The Chinese National Twin Registry (CNTR), established in 2001, is the first and largest population-based twin registry in China. Based on the CNTR, a new twin cohort was recruited from 2011 to study the relationship between environmental risk factors and chronic diseases. So far, 33,874 twin pairs from nine provinces ...
Winandy Susan - - 2013
Ikaros is a transcriptional regulator critical for B- and T-cell development. Recently, it has been shown to play a central role in facilitating rearrangement of antigen receptor genes in B cells. Whether or not it had a similar function in this process in T cells, however, was a mystery. In ...
Peng Weina - - 2013
The electrical properties of nanostructures are extremely sensitive to their surface condition. In very thin two-dimensional crystalline-semiconductor sheets, termed nanomembranes, the influence of the bulk is diminished, and the electrical conductance becomes exquisitely responsive to the structure of the surface and the type and density of defects there. Its understanding ...
Cao Yuebin - - 2013
Traditional Pt counter electrodes in quantum dot sensitized solar cells suffer from a low electrocatalytic activity and instability due to irreversible surface adsorption of sulfur species incurred while regenerating polysulfide (Sn2-/S2-) electrolytes. To overcome such constraints, chemically synthesized Cu2ZnSn(S1-xSex)4 nanocrystals were evaluated as an alternative to Pt. The resulting chalcogenides ...
Fortin Carole - - 2013
ABSTRACT The objective of this study was to explore whether differences in standing and sitting postures of youth with idiopathic scoliosis could be detected from quantitative analysis of digital photographs. Standing and sitting postures of 50 participants aged 10-20-years-old with idiopathic scoliosis (Cobb angle: 15° to 60°) were assessed from ...
Morales Javier O - - 2013
A novel method for the manufacture of protein/peptide-containing submicron particles was developed in an attempt to provide particles with increased activity while using high energy input technologies. The method consists of antisolvent co-precipitation from an aqueous solution containing both an amino acid core material (e.g. D,L-valine), and either bovine serum ...
Omland Petter M - - 2013
OBJECTIVE.-: We intended to study the effect of check size on visual evoked potential habituation in interictal migraine, using the faster 3 per second reversal rate and an improved analytic procedure with block-number blinding. BACKGROUND.-: Habituation in migraineurs has been extensively studied with visual evoked potentials. Despite discrepant results, possibly ...
Menaker Tasha A - - 2013
Prostitution among female youth has been largely misunderstood, trivialized, or ignored. Increased attention has been directed toward juvenile female delinquency, particularly related to the overlap in their status as victims and offenders. Areas in this research continue to be underinvestigated, however, especially with regard to public perceptions of commercially sexually ...
Omer Saad B - - 2013
In a 2X2-factorial trial, the efficacy of influenza vaccine (TIV) in pregnancy plus infant pneumococcal conjugate vaccine (PCV7) was higher than TIV or PCV alone. During the influenza circulation period, efficacy of TIV+PCV7 was 72.4% (95%CI: 30.2%-89.1%) against febrile respiratory illness and 66.4% (95%CI: 14.3%-86.9%) against medically-attended acute respiratory illness.
Sizeland Katie H - - 2013
Collagen is the main structural component of leather, skin and some other applications such as medical scaffolds. All of these materials have a mechanical function, so the manner in which collagen provides them with their strength is of fundamental importance and was investigated here. We show that the tear strength ...
Vitarelli Antonio - - 2013
AIMS: Previous studies have shown distinct models of cardiac adaptations to the training in master athletes and different effects of endurance and strength-training on cardiovascular function. We attempted to assess left-ventricular (LV) function, aortic (Ao) function, and right-ventricular (RV) function in athletes with different forms of training by using three-dimensional ...
Smith Cameron M - - 2013
ABSTRACT: BACKGROUND: Ulceration of the esophageal squamous mucosa (ulcerative esophagitis) is a pathological manifestation of gastroesophageal reflux disease, and is a major risk factor for the development of Barrett's esophagus. Barrett's esophagus is characterised by replacement of reflux-damaged esophageal squamous epithelium with a columnar intestinal-like epithelium. We previously reported discovery ...
Naderi Elin Hallan - - 2013
B cell precursor acute lymphoblastic leukaemia (BCP-ALL) is the most commonly occurring paediatric cancer. Despite its relatively good prognosis, there is a steady search for strategies to improve treatment effects, and to prevent the undesired side effects on normal cells. In the present paper we demonstrate a differential effect of ...
García Gómez Montserrat - - 2013
OBJECTIVE: Spain, and some of its regions in particular, report higher rates of occupational diseases than many other countries in Europe. We describe the distribution and temporal trend of compensated occupational diseases among the working population of the Basque Country, a heavy industrialized Spanish region, from 1990 to 2008. METHODS: ...
Talcott G Wayne - - 2013
INTRODUCTION: Tobacco use among military personnel is associated with significant health care expenditures, lost productivity, and compromised combat readiness. The prevalence remains high among military personnel and may increase in high-risk situations such as deployment. We assessed the prevalence of tobacco use across the deployment cycle, changes in tobacco use ...
Nakamura Yusuke - - 2013
The binding site specificity of the ternary complexes, [M(ii)(phen)(edda)] (M(ii) = Pt(2+) and Zn(2+); phen = 1,10-phenanthroline; edda = N,N'-ethylenediaminediacetic acid), for the self-complementary oligonucleotides (ODNs), ds(C(1)G(2)C(3)G(4)A(5)A(6)T(7)T(8)C(9)G(10)C(11)G(12))(2) (ODN1) and ds(C(1)G(2)C(3)G(4)T(5)A(6)T(7)A(8)C(9)G(10)C(11)G(12))(2) (ODN2), was studied by NMR measurements. The results indicated that [Pt(ii)(phen)(edda)] was partially intercalated between C(3)/G(10) and G(4)/C(9) base pairs ...
Rauda Iris E - - 2013
The assembly of ligand-stripped CdSe nanocrystals into hierarchical mesoporous architectures via polymer templating is reported. The nanocrystal-based porous CdSe combines micropores, created at the juncture between nanocrystals, and mesopores, created by the polymer template, to yield a high surface-area material with accessible pores, while preserving the optical and electronic properties ...
Caparos Serge - - 2013
Local, as opposed to global, perceptual bias has been linked to a lesser ability to attend globally. We examined this proposed link in Himba observers, members of a remote Namibian population who have demonstrated a strong local bias compared with British observers. If local perceptual bias is related to a ...
Cummings Steven R - - 2013
Drug treatment for osteoporosis typically begins with an oral bisphosphonate, regardless of initial bone mineral density (BMD) or fracture risk, and decisions to continue or change treatment are often based on evidence of response to treatment based on changes in BMD, bone turnover markers, and occurrence of fractures. This pattern ...
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