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Fujita Kimikazu - - 2013
Plant lycopene exhibits antioxidant activity in animal tissues. Transient cerebral ischemia/reperfusion in Mongolian gerbils resulted in delayed neuronal death in hippocampal regions. We examined the antioxidant effects of lycopene because we expected lycopene to attenuate ischemia-related neuronal damage by controlling apoptosis at the gene level. The gerbils were divided into ...
Hlaváček Jan - - 2013
Oostatic peptides are organic molecules, which influence an insect reproduction due to a regulation of the eggs development. It was proved that decapeptide-H-Tyr-Asp-Pro-Ala-Pro-Pro-Pro-Pro-Pro-Pro-OH (YDPAPPPPPP)-isolated from mosquito Aedes aegypti, inhibits trypsin activity in the midgut of the mosquito. Therefore, it was named trypsin-modulating oostatic factor (Aea-TMOF). Feeding the recombinant cells with ...
Azevedo Valderilio Feijó - - 2013
The objective of the study was to investigate the association between IL-8 and other biomarkers of endothelial dysfunction (MCP-1, V-CAM, I-CAM) and the disease activity scores in a sample of 54 patients with ankylosing spondylitis (AS) without use of biological agents. Fifty-four AS patients without treatment with anti-TNFs agents between ...
Park Jun-Koo - - 2013
We investigate several approaches to coarse grained normal mode analysis on protein residual-level structural fluctuations by choosing different ways of representing the residues and the forces among them. Single-atom representations using the backbone atoms C( α ), C, N, and C( β ) are considered. Combinations of some of these ...
Cho C E - - 2013
Background:High multivitamin (10-fold AIN-93G, HV) diets fed during pregnancy to Wistar rats increase characteristics of metabolic syndrome in offspring when weaned to the recommended vitamin (RV) diet.Objective:To determine whether the effects of HV gestational diets on obesogenic phenotypes in the offspring arise as a consequence of altered hypothalamic control of ...
Taing Meng-Wong - - 2013
Plant phytochemicals are increasingly recognised as sources of bioactive molecules which may have potential benefit in many health conditions. In mangoes, peel extracts from different cultivars exhibit varying effects on adipogenesis in the 3T3-L1 adipocyte cell line. In this study, the effects of preparative HPLC fractions of methanol peel extracts ...
Essam Tamer - - 2013
An algal-bacterial microcosm was synthetically constructed of Chlorella vulgaris MMl and Pseudomonas MTl. This microcosm was able to treat simulated wastewater supplemented with mixtures of phenol and pyridine up to 4.6 and 4.4 mM, respectively, in a continuous stirred tank bioreactor (CSTR) using photosynthetic oxygenation. Complete pollutant removal and detoxification and ...
Nardelli Silvia - - 2013
HRQoL is impaired in cirrhosis. Establishing the relevance of depression, anxiety, alexithymia and cirrhosis stage on the patients' HRQoL. Sixty cirrhotics underwent a neuropsychological assessment, including ZUNG-SDS, STAI Y1-Y2 and TAS-20. Minimal hepatic encephalopathy (MHE) was detected by PHES, HRQoL by Short-Form-36 (SF-36). Depression was detected in 34 patients (57 %, ...
Bajo-Grañeras Raquel - - 2013
PURPOSE: Inverse correlations of apolipoprotein D (ApoD) expression with tumor growth have been shown, therefore proposing ApoD as a good prognostic marker for diverse cancer types, including colorectal cancer (CRC). Besides, ApoD expression is boosted upon oxidative stress (OS) in many pathological situations. This study aims at understanding the role ...
Poppe Heiko - - 2013
We describe a woman presenting primarily with slowly progressing scarring alopecia. Course, symptoms, and clinical picture were highly suggestive for lichen planus. But mycological investigations revealed that cicatricial alopecia was caused by a specific infection with Trichophyton schoenleinii running a chronic course with minimal skin inflammation.
Paciaroni Alessandro - - 2013
The coherent excitations of DNA hydration water at 100K have been investigated by neutron scattering spectroscopy to extract the excess signal of D2O-hydrated DNA with respect to dry DNA samples. A structural characterization of the sample, through the analysis of the static structure factor, has suggested that DNA hydration water ...
Goodrich S H - - 2013
In an inbred population, selection may reduce the frequency of deleterious recessive alleles through a process known as purging. Empirical studies suggest, however, that the efficacy of purging in natural populations is highly variable. This variation may be due, in part, to variation in the expression of inbreeding depression available ...
Nasuti Gabriella - - 2013
BACKGROUND: A recent meta-analysis on affective judgment and physical activity in adults yielded a medium effect-sized relationship. Despite narrative reviews and topic interest, a meta-analysis in youth has not yet been conducted. PURPOSE: This study aims to appraise the overall effect of affective judgment on physical activity in youth via ...
Chou Cheng Hsiang - - 2013
The prevalence of and psychosocial risks for suicide attempts was investigated in college students in Taiwan by gender, after controlling for depressive symptoms. Self-reported data were collected from a nationally representative sample of 2,835 college students; 11.90% of females and 8.87% of males reported they had attempted suicide in the ...
Harcourt Brooke E - - 2013
Glycaemic control, reduction of blood pressure using agents that block the renin-angiotensin system and control of dyslipidaemia are the major strategies used in the clinical management of patients with diabetes mellitus. Each of these approaches interrupts a number of pathological pathways, which directly contributes to the vascular complications of diabetes ...
Hsieh Ru - - 2013
ABSTRACT Objective: To investigate possible correlations between the incidence and severity of Bell's palsy and seasonal variations in Taiwan. Methods: We studied data on the incidence of Bell's palsy over a 3-year period in Taiwan. The electroneurographic quotient was used as an index for the severity of nerve involvement. A ...
Romeo José S - - 2013
Publicly available genomic data are a great source of biological knowledge that can be extracted when appropriate data analysis is used. Predicting the biological function of genes is of interest to understand molecular mechanisms of virulence and resistance in pathogens and hosts and is important for drug discovery and disease ...
Suzuki Lisandra Akemi - - 2013
In the present study, an enzyme-linked immunosorbent assay (ELISA) standardized with vesicular fluid of Taenia solium cysticerci was used to screen for IgG (total and subclasses) and IgE antibodies in cerebrospinal fluid (CSF) samples from patients with neurocysticercosis showing intrathecal production of specific IgG antibodies and patients with other neurological ...
Alcaide Benito - - 2013
The divergent gold-catalysed reactivity (C(sp(2))-H versus C(sp(3))-H) of aryloxy-tethered allenes has been uncovered.
Horne Steven D - - 2013
Assisted reproductive technologies have been used to achieve pregnancies since the first successful test tube baby was born in 1978. Infertile couples are at an increased risk for multiple miscarriages and the application of current protocols are associated with high first-trimester miscarriage rates. Among the contributing factors of these higher ...
Feinle-Bisset Christine - - 2013
Dietary factors are increasingly recognized to have an important role in triggering symptoms in a large proportion of patients with functional dyspepsia. Fatty foods seem to be the main culprits, but other foods (including carbohydrate-containing foods, milk and dairy products, citrus fruits, spicy foods, coffee and alcohol) have also been ...
Shek Yuen Lai - - 2013
We report the first application of volume and compressibility measurements to characterization of interactions between cosolvents (osmolytes) and globular proteins. Specifically, we measure the partial molar volumes and adiabatic compressibilities of cytochrome c, ribonuclease A, lysozyme, and ovalbumin in aqueous solutions of the stabilizing osmolyte glycine betaine (GB) at concentrations ...
Shao Zhen - - 2013
BACKGROUND: Reduction malarplasty via an intraoral approach for correction of a prominent malar complex is quite popular in the Orient. However, one point of fixation in the anterior zygoma body area, the most widely used method, sometimes is insufficient and likely to result in malunion and cheek drooping. We designed ...
Karlsson M K - - 2013
The proportion of elderly in the society increases and fall frequency increases with advancing age. Many falls result in fractures and also soft tissue injuries, longstanding pain, functional impairment, reduced quality of life, increased mortality, and excess in healthcare costs. Due to the magnitude of these negative effects, a variety ...
Cunningham L - - 2013
BACKGROUND: Tourniquet use in orthopaedic surgery is common practice. However, the technique varies among Irish orthopaedic surgeons and there are no standard guidelines. AIM: To analyse trends in tourniquet use among Irish orthopaedic surgeons. METHODS: Ninety-two Irish orthopaedic consultants were sent a 15-survey question about tourniquet use by post. RESULTS: ...
Gevers Tom J G - - 2013
Polycystic liver disease (PLD) is arbitrarily defined as a liver that contains >20 cysts. The condition is associated with two genetically distinct diseases: as a primary phenotype in isolated polycystic liver disease (PCLD) and as an extrarenal manifestation in autosomal dominant polycystic kidney disease (ADPKD). Processes involved in hepatic cystogenesis ...
Negri F V - - 2013
Antibody-dependent cellular cytotoxicity (ADCC), which is activated by effector cells via immunoglobulin G (IgG) fragment C receptors (FcRs), was proposed as a mechanism of cetuximab efficacy. Peripheral blood mononuclear cells (PBMCs) from 23 healthy donors and 13 patients with metastatic colorectal cancer (mCRC) treated with cetuximab were tested for FcγR ...
Yomo Shoji - - 2013
Advances in chemotherapy for breast cancer (BC) have prolonged overall survival, especially for patients with human epidermal growth factor receptor-2 (HER2) positive cancer. We evaluated the effectiveness and limitations of stereotactic radiosurgery (SRS) for brain metastases (BM) from BC in conjunction with molecular targeting chemotherapy. Outcomes were retrospectively reviewed in 80 ...
Hu Ye - - 2013
Activity cliffs are formed by pairs or groups of structurally similar compounds with significant differences in potency. They represent a prominent feature of activity landscapes of compound data sets and a primary source of structure-activity relationship (SAR) information. Thus far, activity cliffs have only been considered for active compounds, consistent ...
Hao Yuanfeng - - 2013
The discovery of several new loci for resistance to Hessian fly was reported here. QHf.uga-6AL, the late HR61 was recognized from wheat cultivar 26R61 on the distal end of 6AL with resistance to both biotypes E and vH13. It is the first gene or QTL found on this particular chromosome. ...
Pagnotti Vincent S - - 2013
Solvent Assisted Ionization Inlet (SAII) produces ions in a heated inlet to a mass spectrometer from aqueous and aqueous/organic solutions with high sensitivity. However, the use of acid modifiers, which typically aids electrospray ionization, generally results in ion suppression in SAII. Here we demonstrate that the use of carbonation and ...
Ustün Kemal - - 2013
Rheumatological diseases and periodontal disease are both characterized by dysregulation of the host inflammatory response. The aim of this study was to determine the possible relationship between periodontitis and psoriatic arthritis (PsA). Fifty-one adults with PsA (27 men and 24 women; mean age 41.73 ± 11.27 years) and 50 age- and gender-balanced systemically ...
Dai Baozhen - - 2013
This study examined the regional inequity in the New Cooperative Medical Scheme (NCMS) financing in Jiangsu, China. Counties were classified into three categories according to socio-economic development level: South Jiangsu, Middle Jiangsu and North Jiangsu. Five counties (Changshu, Danyang, Gaoyou, Jiangyan and Ganyu) were selected on the basis of the ...
Pang Judy C - - 2013
OBJECTIVE: Endoscopic ultrasound-guided fine-needle aspiration and bile duct brushings are utilized in the cytologic evaluation of solid and cystic pancreaticobiliary tract lesions. We sought to determine the diagnostic accuracy of cytology. METHODS: Five hundred seventy-nine pancreatic resections with 727 corresponding cytology specimens were identified from 1997 to 2012. Histologic diagnoses ...
Quigley Eamonn M M - - 2013
GERD and functional dyspepsia are the two most prevalent upper gastrointestinal disorders. Gastro-oesophageal reflux is most commonly diagnosed using the cardinal symptoms of heartburn and regurgitation. Patients might also be diagnosed using a questionnaire, after empiric treatment with an acid suppressant, after upper endoscopy or by pH testing. Functional dyspepsia ...
Schvey N A - - 2013
Objective:To investigate the influence of a defendant's weight on simulated jurors' perceptions of guilt.Design and methods:Participants were 471 lean and overweight adults (mean body mass index: 25.34±5.91) who read a vignette describing a case of check fraud while viewing one of four images of the alleged defendant (a lean male, ...
Kang Jung Won - - 2013
Platelets play a critical role in pathogenesis of cardiovascular disorders and strokes. The inhibition of platelet function is beneficial for the treatment and prevention of these diseases. In this study, we investigated the anti-platelet activity of erythro-(7S,8R)-7-acetoxy-3,4,3`,5`-tetramethoxy-8-O-4`-neolignan (EATN), a neolignan isolated from Myristica fragrans, using human platelets. EATN preferentially inhibited ...
Wang Lili - - 2013
New Au@SnO(2) yolk-shell nanospheres have been successfully synthesized by using Au@SiO(2) nanospheres as sacrificial templates. This process is environmentally friendly and is based on hydrothermal shell-by-shell deposition of polycrystalline SnO(2) on spheriform Au@SiO(2) nanotemplates. Au nanoparticles can be impregnated into the SnO(2) nanospheres and the nanospheres show outer diameters of ...
Wolf M E - - 2013
BACKGROUND AND PURPOSE: The ASCO score has the advantage of allowing a more comprehensive characterization of ischaemic stroke patients and their risk factors, as reflected in different grades of evidence of atherosclerotic changes (A), small vessel disease (S), potential cardiac (C) or other (O) sources. It might also help to ...
Welling Lisa L M - - 2013
Recent studies investigating the relationship between self-reported sexual desire and attraction to same- and opposite-sex individuals have found that homosexual men's sexual desire is positively correlated with their self-reported attraction to own-sex individuals only, while homosexual women's sexual desire is positively correlated with their self-reported attraction to both men and ...
Teixeira Celia - - 2013
Use of alcohol and illicit drugs is a common finding among HIV-infected individuals, but there are many open questions about its impact on adherence to antiretroviral therapy and virological outcomes. Our study aimed to evaluate the impact of the use of alcohol and illicit drugs on the adherence to antiretroviral ...
Gho Sheridan A - - 2013
PURPOSE: Side effects as a result of breast cancer treatment may have a lasting detrimental impact on quality of life. Exercise has been shown to be an effective intervention in post-treatment care. This study aimed to gain a better understanding of breast cancer treatment-related side effects through identifying potential patient ...
Li Jian-Ying - - 2013
The applications of endohedral non-metallic fullerenes are limited by their low production rate. Recently, an explosive method developed in our group shows promise to prepare He@C(60) at fairly high yield, but the mechanism of He inserting into C(60) cage at explosive conditions was not clear. Here, ab initio molecular dynamics ...
Liu Juan - - 2013
Long-term excessive fluoride intake is known to be toxic and can lead to fluorosis and bone pathologies. However, the cellular mechanisms underlying sodium fluoride-induced cytotoxicity in the cecal tonsil lymphocytes are not well understood. The aims of this study were to investigate the effects of high dietary fluorine on apoptosis ...
Blood Emily A - - 2013
Depressed adolescents are more likely to engage in sexual risk behaviors than their non-depressed peers. The objectives of this study were (1) to examine whether affective states predicted subsequent condom use, directly or indirectly through contextual factors and (2) to compare results obtained from structural equation models versus non-linear mixed ...
Lin Chun-Liang - - 2013
Magnetic properties and surface structures of Ni/Cu(100) ultrathin films are studied by means of magneto-optical Kerr effect and in situ scanning tunneling microscopy in combination with cyclic voltammetry. At the initial stage of Ni deposition on a Cu(100) electrode, nickel atoms attach onto the steps and the surface shows single ...
Fitzpatrick Sheila M - - 2013
We identified and field-tested the sex pheromones of Dasineura oxycoccana (Johnson) (Diptera: Cecidomyiidae) midges collected from cranberry, Vaccinium macrocarpon Aiton, and from highbush blueberry, Vaccinium corymbosum L., commonly named cranberry tipworm (CTW) and blueberry gall midge (BGM), respectively. Coupled gas chromatographic-electroantennographic detection (GC-EAD) analyses of pheromone gland extract from the ...
Fernandez-Teruel C - - 2013
Abstract 1. The objective was to characterize the in vivo absorption and bioavailability (BA) of a low solubility, high permeability fluoroquinolone (CNV97101) that precipitates in the gastrointestinal (GI) tract by mathematical modeling approach. 2. In situ rat intestinal perfusion studies were performed to characterize the absorption mechanism. The oral fraction ...
Kerridge Andrew - - 2013
The restricted-active-space self-consistent-field methodology is successfully applied to the study of free base- and regular metalloporphyrins, the latter containing magnesium and zinc central ions. It is shown that inclusion of all excitations involving the Gouterman frontier orbitals in the RAS2 subspace results in a numerically stable approach, producing highly accurate ...
Esser D - - 2013
Aldehyde dehydrogenases (ALDHs) have been well established in all three domains of life and were shown to play essential roles, e.g., in intermediary metabolism and detoxification. In the genome of Sulfolobus solfataricus, five paralogs of the aldehyde dehydrogenases superfamily were identified, however, so far only the non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase (GAPN) ...
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