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Results 301 - 350 of 2981
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Zou Na - - 2013
Pancreatic beta cells act as glucose sensors, in which intracellular ATP ([ATP](i)) are altered with glucose concentration change. The characterization of voltage-gated sodium channels under different [ATP](i) remains unclear. Here, we demonstrated that increasing [ATP](i) within a certain range of concentrations (2-8 mM) significantly enhanced the voltage-gated sodium channel currents, compared ...
Sullivan A L - - 2013
Study design:Cross-sectional study.Objectives:To examine predictors of oral health in people with spinal cord injury (SCI).Methods:Ninety-two people with SCI (6 months, 44% cervical level) completed questionnaires and underwent oral examination. Socio-economic, injury-related and oral habits variables were used for predicting Oral Health Score (OHS); Decayed, Missing and Filled Teeth (DMFT) score; ...
Guardia Pablo - - 2013
Metal-semiconductor nanocrystal heterostructures are model systems for understanding the interplay between the localized surface plasmon resonances in the metal domain and the relaxation of the excited carriers in the semiconductor domain. Here we report the synthesis of colloidal Au2Cd (core)/CdSe (shell) nanocrystal heterostructures, which were characterized extensively with several structural ...
Allerson M W - - 2013
Influenza A viruses are common causes of respiratory disease in pigs and can be transmitted among multiple host species, including humans. The current lack of published information on infection dynamics of influenza viruses within swine herds hinders the ability to make informed animal health, biosecurity and surveillance programme decisions. The ...
Pressman Mark R - - 2013
As noted by Ohayon et al.,(1) nocturnal wandering (NW) is not synonymous with sleepwalking. NW may also refer to wandering during the night due to epilepsy. Alcohol intoxication can also result in drunken behavior while awake, but this type of cognitive impairment may be undistinguishable from other forms of NW. ...
Bezerra Dandara Monalisa - - 2013
ABSTRACT: BACKGROUND: At least 511 species of birds occur in the semiarid region of northeastern Brazil and many of them interact with human populations in a number of different ways, including their use in zootherapeutics and their links with local beliefs. OBJECTIVE: The present work examined these types of birds/human ...
Bartsch Thorsten - - 2013
Transient amnesic syndromes are striking clinical phenomena that are commonly encountered by physicians in acute medical settings. Diagnosis of such syndromes can be challenging, and their causes have been debated for over 50 years. Critical clinical distinctions, such as between transient global amnesia (TGA) and transient epileptic amnesia (TEA), as ...
Alshehri Ali - - 2013
The purpose of the present work was to elucidate the mechanisms underlying the endothelium-dependent and endothelium-independent components of the vascular relaxation induced by a water-soluble and ruthenium-based carbon monoxide (CO)-releasing agent, tricarbonylchloro(glycinato)ruthenium(II) (CORM-3). Changes in isometric tension and cyclic guanosine monophosphate (cGMP) production were measured in isolated aortic rings from ...
Kunii Y - - 2013
Dopamine- and cAMP-regulated phosphoprotein of molecular weight 32 kDa (DARPP-32 or PPP1R1B) has been of interest in schizophrenia owing to its critical function in integrating dopaminergic and glutaminergic signaling. In a previous study, we identified single-nucleotide polymorphisms (SNPs) and a frequent haplotype associated with cognitive and imaging phenotypes that have been ...
Rinaldi I - - 2013
Ion beams exhibit a finite range and an inverted depth-dose profile, the Bragg peak. These favorable physical properties allow excellent tumor-dose conformality. However, they introduce sensitivity to range uncertainties. Although these uncertainties are typically taken into account in treatment planning, delivery of the intended dose to the patient has to ...
Soon Ying W - - 2013
The photostability of two donor polymers, DPP-TT-T and PTB7, is compared in neat films and blend films with PC(71)BM. In both neat and blend films, PTB7 is shown to be relatively unstable. This observation is shown to correlate with transient optical studies of long lived polymer triplets and with molecular ...
Chen Yi-Ping - - 2013
Heavy metals have long-term adverse impacts on the health of soil ecosystems and even exhibit hazardous influences on human health. Literatures have shown that heavy metals could result in the reduction of crops growth and development and finally result in crops production decline. To determine whether or not ultrasonic vibration ...
Mueller Scott N - - 2013
T-cell responses are initiated within secondary lymphoid organs, and effector T-cells are released into the circulation where they home to inflamed tissues and mediate protective immune responses. Within non-lymphoid tissues, the types of cellular interactions and the dynamics that lead to clearance of infections are still relatively poorly understood. Here ...
Protić Dragana - - 2013
We investigated the effects of resveratrol on rat portal vein (RPV) contractility without endothelium. Contractions were produced by electrical field stimulation of perivascular nerves (EFS), norepinephrine (NE), adenosine 5'-triphosphate (ATP), high K(+) solution and by calcium chloride (CaCl(2) ) in Ca(2+) -free and high K(+) , Ca(2+) -free solution. The ...
Wu Yanying - - 2013
A dopamine (DA) sensor based on a methoxypolyethylene glycol (MPEG) polymer covalently modified glass carbon electrode (GCE) was fabricated by an electroadsorption method. The electrochemical behavior of the sensor towards the catalytic oxidation of DA in pH 5.0 phosphate buffer solution (PBS) was investigated by cyclic voltammetry. The modified electrode ...
Jusková Petra - - 2013
We present a generation of electrochemiluminescence (ECL) signal, based on square shaped gold electrodes with a size of 50 μm positioned inside a fused silica capillary. The ECL was generated using electric pulses with duration in the range from 100 ms to 5 s and an electrical field strength from ...
Wortmann Saskia B - - 2013
Increased urinary 3-methylglutaconic acid excretion is a relatively common finding in metabolic disorders, especially in mitochondrial disorders. In most cases 3-methylglutaconic acid is only slightly elevated and accompanied by other (disease specific) metabolites. There is, however, a group of disorders with significantly and consistently increased 3-methylglutaconic acid excretion, where the ...
Chen Xiao-Yan - - 2013
The carboxyl-functionalized phosphonium ionic liquid (IL), [HCTMP][Tf(2)N], enabled the directed nucleation of monomeric or dimeric uranyl(vi) compounds. This new IL is the first carboxyl-functionalized IL which is liquid at room temperature and exhibits a wider electrochemical window and lower melting point than its ammonium analogue.
Scarpa Marco - - 2013
BACKGROUND: The main outcome parameters in oesophageal surgery have traditionally been morbidity and mortality, but quality of life (QL) has become an important consideration in view of the severity and persistence of postoperative symptoms. The aim of this study was to analyse QL before and after oesophagectomy for oesophageal cancer ...
Dunn Mary - - 2013
The following paper makes use of Kohutian self-psychology as a hermeneutic for interpreting Marie de l'Incarnation and her perplexing decision to abandon her young son Claude in favor of religious life. The author argues that filtered through the lens of Kohutian self-psychology, Marie de l'Incarnation emerges as a pathological narcissist ...
Wu Jie - - 2013
We studied the electronic structures of a series of fluorene derivatives (p/mPODPFs and p/mPOAPFs) using density functional theory calculations and investigated their performances as host materials in organic light-emitting diodes from three aspects, i.e. triplet energy, ability of charge injection from neighboring organic layer or electrode, and match of the ...
Maya Leticia - - 2013
Canine parvovirus (CPV) comprises three antigenic variants (2a, 2b, and 2c) with different frequencies and genetic variability among countries. Current CPV populations are considered to be spatially structured with relatively little movement of viruses between geographical areas. Here we describe the evolution and population dynamics of CPV in Uruguay from ...
Haine-Schlagel Rachel - - 2013
This study examined whether delivery of psychotherapeutic strategies consistent with common elements of evidence-based (EB) treatments for child disruptive behavior problems was associated with parents' report of treatment effectiveness. The intensity of delivery of practice elements consistent with EB treatments was coded from a random sample of 538 videotaped psychotherapy ...
Zajkoska Petra - - 2013
Immobilization is one of the great tools for developing economically and ecologically available biocatalysts and can be applied for both enzymes and whole cells. Much research dealing with the immobilization of Escherichia coli has been published in the past two decades. E. coli in the form of immobilized biocatalyst catalyzes ...
Lee Sunhee - - 2013
Fatty acyl-acyl carrier protein (ACP) thioesterase (acyl-ACP TE) from Streptococcus pyogenes (strain MGAS10270) was codon-optimized and expressed in Escherichia coli K-12 W3110 and Escherichia coli K-12 MG1655. By employing codon-optimized S. pyogenes acyl-ACP TE to improve the total free fatty acids (FFAs) and to tailor the composition of FFAs, high-specificity ...
Hartmann Adrian A - - 2013
Changes in frequency and intensity of drought events are anticipated in many areas of the world. In pasture, drought effects on soil nitrogen (N) cycling are spatially and temporally heterogeneous due to N redistribution by grazers. We studied soil N cycling responses to simulated summer drought and N deposition by ...
Yigit Serbulent - - 2013
Genetic risk factors are known to contribute to the etiology of multiple sclerosis (MS). Patients with familial Mediterranean fever (FMF) have susceptibility to develop MS. Mediterranean fever (MEFV) gene has already been identified as being responsible for FMF. The aim of this study was to explore the frequency of missense ...
Chen Diao - - 2013
Room temperature zinc-mediated diastereoselective allylation or propargylation of isatin-derived N-tert-butanesulfinyl ketimines for synthesis of highly enantiomerically enriched tetrasubstituted 3-aminooxindoles is described.
Zhao Shuai - - 2013
Xanthomonas oryzae pv. oryzae (Xoo) is the causal agent of rice bacterial leaf blight, one of the most important rice bacterial diseases in China and many other countries. The upstream portions of 41 candidate genes encoding non-transcription activator-like effectors of Xoo Chinese strain 13751 were fused with the coding sequence ...
Tan Meng How - - 2013
Landmark events occur in a coordinated manner during pre-implantation development of the mammalian embryo, yet the regulatory network that orchestrates these events remains largely unknown. Here, we present the first systematic investigation of the network in pre-implantation mouse embryos using morpholino-mediated gene knockdowns of key embryonic stem cell (ESC) factors ...
Thimm Eva - - 2013
Aim of the study was the evaluation of health-related quality of life (HRQoL) and the detection of deviant behavior in early-treated children and adolescents with PKU in comparison with healthy peers. Special focus was laid on the impact of compliance with treatment as defined by the national recommendations on HRQoL. ...
Hernandez Frank J - - 2013
Molecular gates have received considerable attention as drug delivery systems. More recently, aptamer-based gates showed great potential in overcoming major challenges associated with drug delivery by means of nanocapsules. Based on a switchable aptamer nanovalves approach, we herein report the first demonstration of an engineered single molecular gate that directs ...
Hoffmann Toni - - 2013
Single molecule force spectroscopy has emerged as a powerful approach to examine the stability and dynamics of single proteins. We have completed force extension experiments on the small cold shock protein B from Thermotoga maritima, using a specially constructed chimeric polyprotein. The family of cold shock proteins is evolutionarily highly ...
New P W - - 2013
Study design:Multifaceted: extensive discussions at workshop and conference presentations, survey of experts and feedback.Objectives:Present the background, purpose and development of the International Spinal Cord Injury (SCI) Data Sets for Non-Traumatic SCI (NTSCI), including a hierarchical classification of aetiology.Setting:International.Methods:Consultation via e-mail, presentations and discussions at ISCoS conferences (2006-2009), and workshop (1 ...
Hu Bing - - 2013
(-)-Epigallocatechin-3-gallate (EGCG), one representative of the well-studied chemopreventive phytochemicals but with low bioavailability, was encapsulated in mono-dispersed nanoparticles that were assembled from bioactive caseinophosphopeptides (CPP) and chitosan (CS). The encapsulation efficiency of EGCG in CS-CPP nanoparticles ranged from 70.5 to 81.7%, meanwhile, the in vitro release of EGCG from CS-CPP ...
Eleftheriadis Theodoros - - 2013
PURPOSE: Acquired immunity is impaired in hemodialysis (HD) patients, and decreased T cell number may contribute. Receptor activator of nuclear factor-κB ligand (RANKL) and osteoprotegerin (OPG) are expressed in cells of the immune system and affect T cell development, homeostasis and proliferation. Serum levels of RANKL and OPG and their ...
Phillip Edward E - - 2013
Sterilization conditions need to be optimized to effectively neutralize the bioburden while using short exposure times for minimizing the changes in chemical composition, material properties and device architecture. Towards this goal, effects of ethylene oxide (EtO) exposure parameters such as time, temperature, humidity, and EtO concentration on the polymer properties ...
Consedine Nathan S - - 2013
Given global demand on health workforces, understanding student enrollment motivations are critical. Prior studies have concentrated on variation in career and lifestyle values; the current work evaluated the importance of disgust sensitivity in the prediction of health career interests. We argue that emotional proclivities may be important and that disgust ...
Khan Farid - - 2013
PURPOSE: Management of hydrocephalus with insertion of ventriculoperitoneal (VP) shunt is associated with significant complications in both adult and pediatric patients. These may be more common in developing countries due to poor economic conditions and a dearth of available resources. We report a 6 years' experience with VP shunt insertion in ...
Park J-M - - 2013
BACKGROUND: Both vertebrobasilar dolichoectasia (VBD) and cerebral microbleeds (CMBs) are related with the risk of intracerebral hemorrhage. We aimed to examine the relationship between the VBD and CMB in ischaemic stroke patients. METHODS: A consecutive series of 182 patients hospitalized because of ischaemic stroke or transient ischaemic attack (TIA), and ...
Varghese George M - - 2013
The deadly combination of tuberculosis (TB) and human immunodeficiency virus (HIV) currently ravaging the world, taking a toll of about 0.35 million people every year, is one of the major public health crises of the decade. Throughout the course of HIV infection, the risk of acquisition, reactivation, and reinfection of ...
Wernick David G - - 2013
Threats to stable oil supplies and concerns over environmental emissions have pushed for renewable biofuel developments to minimize dependence on fossil resources. Recent biofuel progress has moved towards fossil resource-independent carbon cycles, but environmental issues regarding use of nitrogen fertilizers have not been addressed on a global scale. The recently ...
Verhaeghe Jeroen - - 2013
A novel imaging and signal separation strategy is proposed to be able to separate [(18)F]FDG and multiple [(15)O]H(2)O signals from a simultaneously acquired dynamic PET acquisition of the two tracers. The technique is based on the fact that the dynamics of the two tracers are very distinct. By adopting an ...
Riley Kevin E - - 2013
O-H…X and O-H…O H-bonds as well as C-X…X dihalogen and C-X…O halogen bonds have been investigated in halomethanol dimers (bromomethanol dimer, iodomethanol dimer, difluorobromomethanol…bromomethanol complex and difluoroiodomethanol…iodomethanol complex). Structures of all complexes were optimized at the counterpoise-corrected MP2/cc-pVTZ level and single-point energies were calculated at the CCSD(T)/aug-cc-pVTZ level. Energy decomposition ...
Peng Lan - - 2013
ABSTRACT The spinocerebellar ataxias (SCAs) are a clinically and genetically heterogeneous group of neurodegenerative disorders, among which SCA subtype 13 (SCA13) was found associated with mutations in the KCNC3 gene. Among 522 Chinese Han SCA patients (including familial and sporadic) we have collected since 1995, approximately 40% of them have ...
Løvseth Lise Tevik - - 2013
Concerns about protecting patient's privacy are experienced as a limitation in the opportunity to obtain and utilize social support by many physicians. As resources of social support can modify the process of burnout, patient confidentiality may increase risk of this syndrome by interfering with proper stress adaptation. This study investigates ...
Lernmark Ake - - 2013
Type 1 diabetes mellitus (T1DM) is an autoimmune disorder directed against the β cells of the pancreatic islets. The genetic risk of the disease is linked to HLA-DQ risk alleles and unknown environmental triggers. In most countries, only 10-15% of children or young adults newly diagnosed with T1DM have a ...
Khattak Muhammad - - 2013
Renal cell carcinoma comprises 2-3 % of all adult malignancies and its incidence is increasing. Overall survival of patients with advanced disease has increased over the last decade due to the development of many effective targeted agents. Unfortunately, most patients inevitably develop resistance to these agents. While our understanding of the ...
Mohr Sharif B - - 2013
PURPOSE: The objective of this study was to ascertain whether a relationship exists between pre-diagnostic serum levels of 25-hydroxyvitamin D (25(OH)D) and risk of breast cancer in young women. METHODS: About 600 incident cases of breast cancer were matched to 600 controls as part of a nested case-control study that ...
Linder Brian J - - 2013
Abdominal sacrocolpopexy has been shown to have the highest, most durable success rates among techniques for apical pelvic organ prolapse repair. Recently, there has been increased application of minimally invasive techniques, such as laparoscopic and robotic approaches, to performing a sacrocolpopexy. We report an overview of the literature in order ...
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