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Soulière Marie F - - 2013
The complex class of cobalamin-sensitive riboswitches use a "kissing loop" to regulate gene expression. The molecular details of the recognition and folding mode of this riboswitch have been revealed by recent X-ray structures. These insights together with the identification of RNA polymerase pause sites during transcription have resulted in a ...
Bitume E V - - 2013
Although dispersal distance plays a major role in determining whether organisms will reach new habitats, empirical data on the environmental factors that affect dispersal distance are lacking. Population density and kin competition are two factors theorised to increase dispersal distance. Using the two-spotted spider mite as a model species, we ...
Lundgren-Nilsson Asa - - 2013
ABSTRACT: Purpose: The Psychological General Well Being Index (PGWBI) is a widely used scale across many conditions. Over time issues have been raised about the dimensional structure of the scale, and it has not yet been subjected to scrutiny by modern Psychometric approaches. The current study thus evaluates the PGWBI ...
Zekry Ahmed - - 2013
BACKGROUND: The width of the facial alveolar bone wall is crucial for long-term successful esthetic outcomes of implants immediately placed into extraction sockets. A threshold of 2 mm is recommended to minimize buccal vertical bone resorption. AIM: To assess the width of the facial alveolar bone wall using cone-beam computed tomography ...
Troy Gregory C - - 2013
We describe an opportunistic, disseminated infection in a German shepherd dog associated with two fungal organisms not previously reported to cause disease. Lecythophora canina, a new species here described, was isolated from an osteolytic bone lesion. A fine needle aspirate of the lesion demonstrated septate hyphae. Plectospharella cucumerina (anamorph Plectosporium ...
Ichagichu M - - 2013
BACKGROUND: Drug resistance against first-line antimalarials warrants search for new lead compounds and repurposing of drugs such as methotrexate. Animal models are required for preclinical drug development before clinical testing. This study aimed to develop a preclinical drug development system in baboons infected with Plasmodium knowlesi. METHODS: Protocols for drug ...
Goodenough John B - - 2013
Abstract Each cell of a battery stores electrical energy as chemical energy in two electrodes, a reductant (anode) and an oxidant (cathode), separated by an electrolyte that transfers the ionic component of the chemical reaction inside the cell and forces the electronic component outside the battery. The output on discharge ...
Yao Zi-Jian - - 2013
Open-and-shut case: The cage CC bond cleavage of monosubstituted carborane derivatives at room temperature has now been achieved. This approach, which is facilitated by half-sandwich complexes, provides a facile and direct synthesis of pseudocloso metallacarboranes (see picture; dots indicate carbon atoms).
Brekke Idunn - - 2013
Aims: The authors sought to estimate differences in doctor-certified sickness absence during pregnancy among immigrant and native women. Methods: Population-based cohort study of pregnant women attending three Child Health Clinics in Groruddalen, Oslo, and their offspring. Questionnaire data were collected at gestational weeks 10-20 and 28. The participation rate was ...
Bost V - - 2013
BACKGROUND AND OBJECTIVES: Our objective was to compare the frequency of adverse events (AEs) due to any of the 4 types of fresh-frozen plasma (FFP) prepared and delivered by the French Blood Establishment (EFS) over a 10-year period. Surveillance of AEs and vigilance was performed according to a homogeneous policy. ...
Tahir M Z - - 2013
Background. Given the improved survival of patients requiring decompressive craniectomies, the frequency of subsequent cranioplasties are on the rise. The most feared complication of autologous cranioplasty is infection and one method for reducing the rate of infection, is to store the bone flaps at subnormal temperatures. However, to date there ...
Liu Jia - - 2013
Macromolecular crowding is an ubiquitous phenomenon in living cells that significantly affects the function of enzymes in vivo. However, this effect has not been paid much attention in the research of the immobilization of enzymes onto mesoporous silica. Herein, we report the combined effects of macromolecular crowding and surface hydrophobicity on ...
Walters Braden - - 2013
Recently, Brachypodium distachyon has emerged as a model plant for studying monocot grasses and cereal crops. Using assembled expressed transcript sequences and subsequent mapping to the corresponding genome, we identified 1219 alternative splicing (AS) events spanning across 2021 putatively assembled transcripts generated from 941 genes. Approximately, 6.3% of expressed genes ...
Cronholm Pontus - - 2013
An increased understanding of nanoparticle toxicity and its impact on human health is essential to enable a safe use of nanoparticles in our society. The aim of this study is to investigate the role of a Trojan horse type mechanism for the toxicity of Ag-nano and CuO-nano particles and their ...
Sharma Suvasini - - 2013
PURPOSE: The aim of this study was to evaluate the efficacy of the modified Atkins diet in a randomized controlled trial in children with refractory epilepsy. METHODS: Children aged 2-14 years who had daily seizures despite the appropriate use of at least three anticonvulsant drugs were enrolled. Children were randomized to ...
Moriel P - - 2013
Two studies were conducted to evaluate the effects of pre-weaning limit-fed creep-feed (LFC) with or without trace mineral-fortification on trace mineral status and pre- and post-weaning growth performance of beef calves. At 102 (Exp. 1) and 97 (Exp. 2) d before weaning, Brahman x British cow-calf pairs (calf age = ...
Lyon Richard M - - 2013
ABSTRACT: BACKGROUND: Out-of-hospital cardiac arrest (OHCA) is a common medical emergency with significant mortality and significant neurological morbidity. Helicopter emergency medical services (HEMS) may be tasked to OHCA. We sought to assess the impact of tasking a HEMS service to OHCA and characterise the nature of these calls. METHOD: Retrospective ...
Awad Sherif S - - 2013
BACKGROUND: Vitiligo is a disease of color loss from skin and possibly also from hair. The presence of white hair follicles is known to be a bad prognostic sign. OBJECTIVES: To evaluate the possibility of repigmentation of white hair follicles after epithelial grafting. METHODS: Patients with recalcitrant vitiligo with loss ...
Mitchell Brett G - - 2013
AIM: To quantify the risk of death associated with Clostridium difficile infection, in an Australian tertiary hospital. BACKGROUND: Two reviews examining Clostridium difficile infection and mortality indicate that Clostridium difficile infection is associated with increased mortality in hospitalized patients. Studies investigating the mortality of Clostridium difficile infection in settings outside ...
van Wonderen Jessica H - - 2013
A new pulse sequence: The distances between copper sites of the homotrimeric Cu-containing nitrite reductase were determined by EPR spectroscopy. By exploiting the differences in the electron spin relaxation of the Cu ions, a filtering technique allows the selective removal of distances from a complex distance distribution. This filter technique ...
Sohn Jong Hee - - 2013
BackgroundThe trigeminal nociceptive system plays a pivotal role in the pathophysiology of tension-type headaches (TTH).ObjectiveThis study investigated and compared nociceptive-specific trigeminal pathways in patients with episodic and chronic TTH (ETTH and CTTH, respectively) using the nociceptive blink reflex (nBR) and nociceptive trigeminocervical reflex (nTCR).MethodsWe recorded nBR and nTCR in patients ...
Gerstel L - - 2013
OBJECTIVES: In 2010-2011, recent graduates (2008 or earlier) of the Masters in International Health (MIH) (as offered by over 30 universities and institutions collaborating in the tropEd network) were surveyed. We aimed to examine whether the competencies gained proved appropriate for alumni's current positions and to develop the programme according ...
Costa Casagrande T A - - 2013
This study investigated the correlation between KIT gene expression determined by immunohistochemistry and real-time polymerase chain reaction (RT-PCR) and the rate of tumour recurrence and tumour-related deaths in dogs affected with mast cell tumour (MCT). Kaplan-Meier curves were constructed to compare tumour recurrence and tumour-related death between patients. The log-rank ...
Hoekstra Lisette T - - 2013
Aim: To identify predictors of postoperative ascites after liver resection for patients with or without preoperative portal vein embolization (PVE). Methods: Patients undergoing PVE prior to hepatectomy (PVE group; n = 37) were compared with patients who underwent liver resection without PVE (n = 503). Ascites was defined as postoperative ...
Kay Emma Isobel - - 2013
Human melanocortin 2 receptor accessory protein (hMRAPα) is hypothesised to have functions beyond promoting human melanocortin 2 receptor (hMC2R) functional expression. To understand these potential functions we characterised effects of hMRAPα-FLAG or untagged hMRAPα co-expression with each of the five hMCR subtypes (HA N-terminal tagged and untagged) exogenously expressed in ...
Banati M - - 2013
BACKGROUND: Antibodies against gastrointestinal antigens may indicate altered microbiota and immune responses in the gut. Recent experimental data suggest a connection between gastrointestinal immune responses and CNS autoimmunity. METHODS: Antibodies against gliadin, tissue transglutaminase (tTG), intrinsic factor (IF), parietal cells (PC) and Saccharomyces cerevisiae (ASCA) were screened in the sera ...
Meidinger R G - - 2013
A line of transgenic Yorkshire pigs referred to as the Cassie (CA) line was generated, which possessed a stable, low copy number phytase transgene insertion that enabled phytase secretion in the saliva. This study was conducted to assess growth and efficacy for improving P, Ca, and other macro-mineral utilization in ...
Kurosaki Masayuki - - 2013
This study aimed to develop a model for predicting anemia using the inosine triphosphatase (ITPA) genotype and to evaluate its relationship with treatment outcome. Patients with genotype 1b chronic hepatitis C (n = 446) treated with peg-interferon alpha and ribavirin (RBV) for 48 weeks were genotyped for the ITPA (rs1127354) and IL28B ...
Hernández M - - 2013
Zoonotic agents such as Brucella spp., Salmonella spp., Toxoplasma gondii and Trichinella spp., all considered high-risk zoonotic pathogens by the European Food Safety Agency (EFSA), may cause no symptoms of infection in free-range pigs yet still have a significant public health impact. A serological survey was therefore performed to determine ...
Seo Jung Hwan - - 2013
This study reports on dual on-column Fabry-Pérot (FP) cavity sensor-based gas chromatography (GC) of mixtures of volatile organic compounds (VOCs) utilizing an on-chip device, the so called "microfabricated passive preconcentrator/injector (μPPI)". Comprehensive analysis of the sampling, desorption/injection, and compound separation performance of the μPPI-based optofluidic GC system is described. Here, ...
Fischer M - - 2013
Hospitals are implementing a risk management system to avoid patient or surgery mix-ups. The trend is to use preoperative checklists. This work deals specifically with a type of patient identification, which is realized by storing patient data on a patient-fixed medium.In 127 ENT surgeries data relevant for patient identification were ...
Festini Sara B - - 2013
Directed forgetting requires the voluntary control of memory. Whereas many studies have examined directed forgetting in long-term memory (LTM), the mechanisms and effects of directed forgetting within working memory (WM) are less well understood. The current study tests how directed forgetting instructions delivered in a WM task influence veridical memory, ...
Fatehi Pedram - - 2013
In this review, the recent advancements and technical challenges associated with the production of ethanol, butanol and isobutanol via bioconversion routes from celluloses of woody materials are reviewed. Physicochemical processes, e.g. steam explosion, seem to be the most viableprocessfor pretreating woody materials. Although enzymatic hydrolysis is selective, it is rather ...
Williams Joseph Jay - - 2013
Seeking explanations is central to science, education, and everyday thinking, and prompting learners to explain is often beneficial. Nonetheless, in 2 category learning experiments across artifact and social domains, we demonstrate that the very properties of explanation that support learning can impair learning by fostering overgeneralizations. We find that explaining ...
Ma Han - - 2013
ABSTRACT: BACKGROUND: To investigate the association between serum glycosylated hemoglobin (HbA1c) levels and nonalcoholic fatty liver disease (NAFLD) in an elderly Chinese population. METHODS: A cross-sectional study was performed among the 949 retired elderly employees of Zhenhai Refining & Chemical Company Ltd., Ningbo, China. RESULTS: A total of 257 (27.08%) ...
Sueyoshi Eijun - - 2013
Purpose:To investigate the clinical features and outcomes of type B multibarreled (multiple false lumens) aortic dissection (AD) compared with those of double-barreled (single false lumen) AD by using computed tomography (CT).Materials and Methods:The ethics committee approved this study. Informed consent was waived. A total of 221 consecutive patients (127 men; ...
Moore Sally - - 2013
OBJECTIVES: Bortezomib is an effective anti-myeloma therapy but clinical benefit can be limited by neurotoxicity. In newly diagnosed, older patients, modification of the bi-weekly dosing schedule to weekly regimens improves tolerability whilst maintaining efficacy. There is less information on the efficacy and tolerability of weekly bortezomib regimens in the relapsed/refractory ...
Ludbrook John - - 2013
A survey of five journals of physiology or pharmacology for the year 2011 showed that Fisher's exact test was used three times as frequently as Pearson's chi-squared test. I shall argue that neither test is appropriate for analysing 2 × 2 tables of frequency in biomedical research. Pearson's test requires ...
Zhu Xi - - 2013
The metal-organic framework (MOF) was first utilized as the sensing platform for assaying biomolecules. It has also been demonstrated that this novel strategy is effective and reliable for detection of HIV DNA and thrombin with high sensitivity and selectivity.
Chitnis Saurabh S - - 2013
Gas driven: A high-yield approach to sequential fluoride ion abstraction from SbF(3) in the presence of 2,2'-bipyridine gives a series of complexes containing [SbF(2) ](+) , [SbF](2+) , and [Sb](3+) acceptors. The thermodynamically favorable rapid elimination of gaseous Me(3) SiF provides a potentially general approach to enhance the Lewis acidity ...
Höfler Julia - - 2013
Status epilepticus is among the most common neurologic emergencies, with a mortality rate of up to 20%. The most important therapeutic goal is fast, effective, and well-tolerated cessation of status epilepticus. Intravenous phenytoin/fosphenytoin, phenobarbital, or valproate is the current standard treatment after failure of benzodiazepines. Lacosamide as a new antiepileptic ...
Stoyko Stanislav S - - 2013
The pnictides RE(2)Mn(3)Cu(9)Pn(7) (Pn = P, As) have been prepared by stoichiometric reaction of the elements at 800 °C. They are quaternary ordered variants of the hexagonal Zr(2)Fe(12)P(7)-type structure (Pearson symbol hP21, space group P6̅, Z = 1; a = 9.6444(3)-9.5970(7) Å, c = 3.9027(1)-3.7761(3) Å for RE(2)Mn(3)Cu(9)P(7) (RE = ...
Pessina Augusto - - 2013
Current leukaemia therapy focuses on increasing chemotherapy efficacy. Mesenchymal stromal cells (MSCs) have been proposed for carrying and delivery drugs to improve killing of cancer cells. We have shown that MSCs loaded with Paclitaxel (PTX) acquire a potent anti-tumour activity. We investigated the effect of human MSCs (hMSCs) and mouse ...
Shafiei Fereshteh - - 2013
Abstract Objective. This in vitro study evaluated the effect of soft-start curing mode by LED unit on the marginal microleakage of silorane composite restoration. Materials and methods. Class V cavities were prepared on the buccal surfaces of 80 extracted molars at the cementoenamel junction and randomly divided into eight groups. ...
Cranford Steven W - - 2013
The past fifty years have seen a surge in the use of materials for clinical application, but in order to understand and exploit their full potential, the scientific complexity at both sides of the interface-the material on the one hand and the living organism on the other hand-needs to be ...
Anagnostis Panagiotis - - 2013
Background:  Special attention has been given to the effect of vitamin D supplementation on fertility outcomes in both sexes. Aims:  The purpose of this narrative review was to elucidate the role of vitamin D in male and female reproduction, providing current evidence from both animal and human studies. Materials and ...
Shahbazi M A - - 2013
What is known and Objective:  Long-acting intramuscular penicillin G injection is an important product for the management of some severe infections. However, testing the bioequivalence of such long-acting formulations is difficult. Our aim was to undertake such a test using a generic formulation containing 1 200 000 IU of benzathine penicillin G powder ...
Lanni Thomas - - 2013
The aim of this study is to perform a cost analysis to compare adjuvant radiation therapy schedules following breast conserving surgery. Treatment planning and delivery utilization data were modeled for a series of 10 different breast RT techniques. The whole breast (WB) regimens consisted of: (1) Wedge based WB (25 ...
Li J - - 2013
Satellite cells are the resident stem cell population of adult skeletal muscle tissue that is responsible for growth and regeneration. The cells typically congregate near the tips of the muscle fibers and in close proximity to the neural muscular junction (NMJ). Ephrin-A5 is a chemotactic molecule that participates in the ...
Urnikaite Simona - - 2013
Good, cheap light: A new type of D-π-A metal-free organic dye for solid-state dye-sensitized solar cells, employing a hydrazone fragment as π-conjugated bridge, is presented. These dyes are obtained from relatively cheap starting materials, without the use of expensive catalysts, rigorously anhydrous or oxygen-free conditions. The whole synthesis process is ...
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