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Gaspar Emanuelle B - - 2013
Colonization of the nasopharynx by non-pathogenic Neisseria species, including N. lactamica, has been suggested to lead to the acquisition of natural immunity against Neisseria meningitidis in young children. The aim of this study was to identify a model complex of antigens and adjuvant for immunological preparation against N. meningitidis B, ...
Choi V W Y - - 2013
An adaptive response is a biological response where the exposure of cells or animals to a low priming exposure induces mechanisms that protect the cells or animals against the detrimental effects of a subsequent larger challenging exposure. In realistic environmental situations, living organisms can be exposed to a mixture of ...
King Brian A - - 2013
INTRODUCTION: An increasing number of U.S. states and communities have implemented smoke-free policies prohibiting smoking in all indoor workplaces and public areas. Public attitudes toward smoke-free environments are an evidenced-based, key indicator for the successful implementation and enforcement of smoke-free policies. METHODS: Data were obtained from the 2009-2010 National Adult ...
Brandstack Nina - - 2013
Purpose:To evaluate whether quantitative diffusion-tensor tractography can show abnormalities in long association tracts of subjects with symptoms after traumatic brain injury without any visible signs of intracranial or intraparenchymal abnormalities of obvious traumatic origin at routine magnetic resonance (MR) imaging and to determine the number and type of these abnormalities.Materials ...
Kim Jeong-Lim - - 2013
Objective. To investigate respiratory symptoms and respiratory-related absence from work among Swedish health care workers (HCW). Methods. From a postal questionnaire study among a general Swedish working population (n=12 186), we identified 2156 HCW (555 assistant nurses, 377 nurses, 109 physicians and 1115 others), including 429 with mainly cleaning tasks ...
Gümüş Hatice - - 2013
To determine if the specimen without calcification, as depicted on specimen radiography, made any contribution to the final histopathological diagnosis in comparison to the specimen with calcification. The records of 1312 stereotactic vacuum-assisted biopsies for breast microcalcifications between February 2000 and December 2010 were reviewed retrospectively. Following specimen x-ray the ...
Chen Fang - - 2013
HER2 (ErbB2) has been reported to be overexpressed in 20-30% of breast cancer and confers poor survival because of high proliferation and metastasis rates. MicroRNAs are small noncoding RNAs that are responsible for the posttranscriptional regulation of target genes. We found miR-199b-5p inhibited HER2 expression by direct targeting its 3'-untranslated ...
Bai Jiu-Xu - - 2013
Although tamoxifen (TAM), a selective estrogen receptor modulator, has been widely used in the treatment of hormone-responsive breast cancer, its estrogen-like effect increases the risk of endometrial cancer. However, the molecular mechanisms of TAM-induced endometrial carcinoma still remain unclear. In this report, we explored the role of microRNAs (miRNAs) in ...
Quilendrino Ruth - - 2013
Abstract Purpose: To evaluate how corneal deturgescence after Descemet membrane endothelial keratoplasty (DMEK) influences the posterior corneal surface area and the endothelial cell density (ECD) measurements. Materials and Methods: A mathematical model was formulated to estimate the increase in posterior corneal surface area associated with postoperative corneal deturgescence and its ...
Novikov Alexander S - - 2013
The theoretical background of the formation of N-heterocyclic oxadiazoline carbenes through a metal-assisted [2+3]-dipolar cycloaddition (CA) reaction of nitrones R(1) CHN(R(2) )O to isocyanides CNR and the decomposition of these carbenes to imines R(1) CHNR(2) and isocyanates OCNR is discussed. Furthermore, the reaction mechanisms and factors that govern these processes ...
Hadjidemetriou Marilena - - 2013
Abstract Dimethoxycurcumin (DMC) is a lipophilic analog of curcumin found in Curcuma longa Linn., which is known to possess significant activity against various cancer cell lines. The purpose of this study was to develop suitable liposomal formulations in order to overcome DMC's poor water solubility and to study the aggregation ...
Wei Chengzhen - - 2013
In this study, we report the synthesis of monodispersive solid and hollow CdS spheres with structure-dependent photocatalytic abilities for dye photodegradation. The monodispersive CdS nanospheres were constructed with the assistance of the soulcarboxymthyi chitosan biopolymer under hydrothermal conditions. The solid CdS spheres were corroded by ammonia to form hollow CdS ...
Hsu Ching-Sheng - - 2013
BACKGROUND: IL-21R polymorphisms have been identified as potential predictors of virologic outcomes in Western chronic hepatitis C (CHC) patients receiving interferon-based treatment. We aimed to examine the associations of IL-21R genotypes and serum IL-21 levels with virologic responses to interferon-based treatment in Asian CHC patients. METHODS: Genomic and clinical data ...
Lee Sang W - - 2013
Occupational hand eczema is frequent in hospital workers, especially in nurses. A comprehensive understanding regarding hand eczema is essential for establishing proper prevention and treatment strategies. The purpose of this study was to identify the risk factors for hand eczema in hospital nursing staffs. A self-administered questionnaire study was performed ...
Oneal Gail - - 2013
AIM: To report the psychometric testing of the Household Risk Perception and Self-Efficacy in Environmental Risk Reduction instruments using principal components analysis. BACKGROUND: There are limited instruments available to test household risk perception and self-efficacy related to environmental health behaviours. The Household Risk Perception instrument was developed to measure personal ...
Paolini Francesca - - 2013
Cervical, anal, penile and a sub-set of head and neck (HN) tumors are critical health problems caused by high risk Human Papilloma Viruses (HPVs), like HPV type 16. No specific/effective pharmacological treatments exist. A valid preventive vaccination as well as the immunotherapy of persistent infections, pre-cancerous lesions or early-stage cancers ...
Hicks Dg - - 2013
Clinical laboratory testing for human epidermal growth factor receptor-2 (HER2) in patients with newly diagnosed breast and gastric cancer is critically important for therapeutic decisions about adjuvant treatment. The HER2 pathway is a major molecular driver of disease progression in a subset of these solid tumors and the results of ...
Beggs Andrew D - - 2013
Lynch Syndrome, an autosomal dominantly inherited cancer predisposition syndrome is not typically associated with development of breast cancer. We present two cases of loss of mismatch protein expression in breast cancer cases in patients with Lynch Syndrome and discuss the literature surrounding the subject.
Quinn Daniel - - 2013
We present an analytical solution for the shape of a fluid-fluid interface near a nanoscale solid sphere, which is a configuration motivated by common measurements with an atomic force microscope. The forces considered are surface tension, gravity, and the van der Waals attraction. The non-linear governing equation has been solved ...
Paquet F - - 2013
The assessment and management of risks associated with exposures to ionising radiation are defined by the general radiological protection system, proposed by the International Commission on Radiological Protection (ICRP). This system is regarded by a large majority of users as a robust system although there are a number of dissenting ...
Gottlieb Peter - - 2013
Background: By including §69 into the Danish Penal Code, it has since 1975 been possible to use psychiatric measures as legal sanctions for even non-psychotic offenders-if the measure is believed to be preventive of future crime. To be able to decide on the applicability of treatment measures as sanctions in ...
Chen Yongdi - - 2013
In the present study, we investigated the changes in both anti-HAV lgG and anti-HBs lgG levels and compared the antibody seroconversion rates of different doses of combined hepatitis A and hepatitis B vaccine in children. Children who were vaccinated as infants with Hepatitis B vaccine were revaccinated at 5-15 y ...
Li Shuru - - 2013
Inspired by the structure features of micelle, we attempt to synthesize a novel functionalized mesoporous silica nanosphere consisting of a hydrophobic core and a hydrophilic shell. The obtained solid materials were structurally confirmed by N2 sorption, X-ray diffraction (XRD) and transmission electron microscopy (TEM). Their compositions were characterized by Fourier ...
Wehner Astrid - - 2013
Two siblings, a 6-month-old sexually intact male weighing 2.5 kg (cat 1) and a sexually intact female (cat 2) British Shorthair cat weighing 2.3 kg, were examined because of a 3-week history of polyuria, lethargy and laboured breathing. One year previously, another sibling (cat 3) had been presented because of ...
Pena R N - - 2013
The influence that the genetics of species used as food sources has on the human perception of sensory attributes has been rarely addressed in previous studies. Dry-cured hams are high-quality highly appreciated pork products obtained by salting, curing, drying and ageing process. We carried out a Quantitative Trait Loci (QTL) ...
Shane Andi L - - 2013
Identifying neonates with sepsis is complicated by variability in clinical presentation. The incidence of early onset sepsis (EOS) resulting from invasive group B streptococcal (GBS) infections has been notably reduced by the widespread delivery of intrapartum antibiotic prophylaxis. Rates of EOS attributable to non-GBS etiologies have remained constant, and ampicillin-resistant ...
Sun Zhaoqing - - 2013
BACKGROUND: The aim of this study was to describe the incidence, clinical sub-types, and associated risk factors of stroke among rural Chinese adults. METHODS: A population-based sample of 38 949 rural Chinese adults, aged ≥35 years and free from stroke at baseline, were followed from 2004-2006 to 2010. Stroke was defined ...
Laing Emma M - - 2013
Adenovirus 36 (Ad36) is the only adenovirus to date that has been linked with obesity in humans. Our previous studies in late adolescent females suggest that excess weight in the form of fat mass is associated with lower cortical bone strength. The purpose of this study was to assess the ...
Cordeiro Aline - - 2013
Thyroid hormones are important modulators of lipid metabolism because the liver is a primary hormonal target. The hypolipidemic effects of thyroid hormones result from the balance between direct and indirect actions resulting in stimulation of lipid synthesis and lipid oxidation, which favours degradation pathways. Originally, it was believed that thyroid ...
Haag Rainer - - 2013
A new amphiphilic membrane marker based on a water-soluble dendritic polyglycerol perylene imido dialkylester has been designed, synthesized and its optical properties characterized. In water it forms fluorescently quenched micellar self-aggregates but when incorporated into a lipophilic environment, it monomerizes and the highly fluorescent properties of the perylene core are ...
Aspatwar Ashok - - 2013
The catalytically inactive isoforms of carbonic anhydrase (CAs) are known as CA-related proteins (CARPs) VIII, X, and XI. They have highly conserved amino acid sequences. These proteins are predominantly expressed in human and mouse brain, however, their precise roles are poorly known. CARP VIII is functionally associated with motor coordination ...
Senchyk Ganna A - - 2013
Bistriazoles, 1,3-bis(1,2,4-triazol-4-yl)propane (tr(2)pr) and 1,3-bis(1,2,4-triazol-4-yl)adamantane (tr(2)ad), were examined in combination with the rigid tetratopic 1,3,5,7-adamantanetetracarboxylic acid (H(4)-adtc) platform for the construction of neutral heteroleptic copper(II) metal-organic frameworks. Two coordination polymers, [{Cu(4)(OH)(2)(H(2)O)(2)}{Cu(4)(OH)(2)}(tr(2)pr)(2)(H-adtc)(4)]·2H(2)O (1) and [Cu(4)(OH)(2)(tr(2)ad)(2)(H-adtc)(2)(H(2)O)(2)]·3H(2)O (2), were synthesized and structurally characterized. In complexes 1 and 2, the N(1),N(2)-1,2,4-triazolyl (tr) and μ(3)-OH(-) ...
Frid H - - 2013
BACKGROUND: The present study aimed to examine the agreement between measurements of standing height and self-reported height, height measured with a sliding caliper, and height estimated from either demispan or knee height in elderly patients. METHODS: Fifty-five patients (mean age 79 years) at a Swedish hospital were included in this observational ...
Andersson Lars-Magnus - - 2013
Background: The objective of this study was to compare the efficacy of ritonavir boosted atazanavir versus ritonavir boosted lopinavir or efavirenz, all in combination with 2 nucleoside analogue reverse transcriptase inhibitors (NRTIs), over 144 weeks in antiretroviral-naïve HIV-1-infected individuals. Methods: A prospective open-label randomized controlled trial was conducted at 29 ...
Wang Chia-Chen - - 2013
BACKGROUND: Treating cosmetic tattoos using quality-switched lasers is difficult. OBJECTIVE: We used carbon dioxide ablative fractional resurfacing (CO(2) AFR) to remove cosmetic tattoos and examined the pathophysiologic mechanisms involved in this technique in an animal model. METHODS AND MATERIALS: Twelve rats were tattooed on their backs with white and flesh-colored ...
Walsh Andrew J - - 2013
Purpose:To investigate the relationship between iron staining and magnetic resonance (MR) imaging measurements in postmortem subjects with multiple sclerosis (MS).Materials and Methods:Institutional ethical approval was obtained, and informed consent was obtained from the subjects and/or their families. Four MR imaging methods based on transverse relaxation (T2 weighting, R2 mapping, and ...
Maeda Miki H - - 2013
A database of 3D structures of natural metabolites has been developed called 3DMET. During the process of structure conversion from 2D to 3D, we found many structures were misconverted at chiral atoms and bonds. Several popular converters were tested in regard to their conversion accuracy. For verification, three canonical strings ...
Trumbo Daryl R - - 2013
A species' genetic structure often varies in response to ecological and landscape processes that differ throughout the species' geographic range, yet landscape genetics studies are rarely spatially replicated. The Cope's giant salamander (Dicamptodon copei) is a neotenic, dispersal-limited amphibian with a restricted geographic range in the Pacific northwestern USA. We ...
Psychogios Georgios - - 2013
Abstract Conclusion: This study showed that elective neck dissection (ND) resulted in reduced regional recurrences in a selected group of surgically treated patients with pT1-2 carcinomas but did not show any benefit for disease-specific survival (DSS). Furthermore, the importance of pN classification was also verified for this patient group. Objectives: ...
De Mita Stéphane - - 2013
Thanks to genome-scale diversity data, present-day studies can provide a detailed view of how natural and cultivated species adapt to their environment and particularly to environmental gradients. However, due to their sensitivity, up-to-date studies might be more sensitive to undocumented demographic effects such as the pattern of migration and the ...
Kang Ho Min - - 2013
Abstract Conclusion: Contrary to our expectation, that the clinical characteristics of temporal bone fracture would differ in children and adults, we found that the two groups were similar. Objectives: Most studies of temporal bone fractures have been performed in adults. To our knowledge, no study has investigated differences in temporal ...
Bouška Marek - - 2013
Put the right spin on it: Mixed monomeric organotin(IV) chalcogenides of the general formula L(2) Sn(2) EX(2) containing two terminal Sn-X (X=Se, Te) bonds were prepared and were tested as potential single-source precursors for the deposition of semiconducting thin films. Spin-coating deposition of [{2,6-(Me(2) NCH(2) )(2) C(6) H(3) }SnSe](2) (μ-S), ...
Xiao Ni-Guang - - 2013
Human metapneumovirus (hMPV) causes acute respiratory infections in children. The prevalence and clinical characteristics of hMPV were determined in nasopharyngeal aspirates of children in Changsha, China. Reverse transcription-polymerase chain reaction (RT-PCR) or PCR was employed to screen for both hMPV and other common respiratory viruses in 1,165 nasopharyngeal aspirate specimens ...
Kohlmann Alexander - - 2013
Next-generation sequencing platforms have evolved to provide an accurate and comprehensive means for the detection of molecular mutations in heterogeneous tumour specimens. Here, we review the feasibility and practicality of this novel laboratory technology. In particular, we focus on the utility of next-generation sequencing technology in characterizing haematological neoplasms and ...
Brillowska-Dabrowska Anna - - 2013
Microsporum canis, for which the natural hosts are cats and dogs, is the most prevalent zoophilic agent causing tinea capitis and tinea corporis in humans. We present here a diagnostic PCR test for M. canis, since its detection and species identification is relevant to the choice of treatment and to ...
Borhani Haghighi Afshin - - 2013
Background: Endovascular treatment of cerebral venous sinus thrombosis (CVST) includes pharmacological and mechanical thrombolysis. Methods: The authors searched the English literature on CVST from 1990 to 2012 for all case reports or case series of mechanical thrombectomy. Results: A total of 64 patients were treated in all published studies. The ...
Lo Kuan-Hsin - - 2013
This work presents a simple method to generate ordered chromophore/dispersant nanoarrays through a pore-filling process for nanoporous polymer template to enhance chromophore luminescence. Fluorescence results combining with the morphological evolution examined by scanning probe microscopy reveal that the enhanced luminescence intensity reaches the maximum intensity as the nanopores of the ...
Varewijck Aimee J - - 2013
Context:No relationship has been found between improvement in quality of life (QOL) and total IGF-I during GH therapy.Aim:Our aim was to investigate the relationship between IGF-I bioactivity and QOL in GH-deficient (GHD) patients receiving GH for 12 months.Methods:Of 106 GHD patients, 84 on GH treatment discontinued therapy 4 weeks before ...
Clark Ewan R - - 2013
A range of frustrated Lewis pairs (FLPs) containing borenium cations have been synthesised. The catechol (Cat)-ligated borenium cation [CatB(PtBu(3) )](+) has a lower hydride-ion affinity (HIA) than B(C(6) F(5) )(3) . This resulted in H(2) activation being energetically unfavourable in a FLP with the strong base PtBu(3) . However, ligand ...
Scholze Alexandra - - 2013
ABSTRACT: BACKGROUND: Fibulin-1 is one of a few extracellular matrix proteins present in blood in high concentrations. We aimed to define the relationship between plasma fibulin-1 levels and risk markers of cardiovascular disease. METHODS: Plasma fibulin-1 was determined in subjects with chronic kidney disease (n = 32; median age 62.5, ...
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