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Zhong X - - 2013
AIMS/HYPOTHESIS: As microRNA-21 (miR-21) plays a pathological role in fibrosis, we hypothesised that it may be a therapeutic target for diabetic nephropathy. METHODS: Abundance of miR-21 was examined in diabetic kidneys from db/db mice. The therapeutic potential of miR-21 in diabetic kidney injury was examined in db/db mice by an ...
Sugiyama Akihide - - 2013
Repair of recurrent tracheoesophageal fistula (TEF) after repair of congenital esophageal atresia continues to be a difficult problem. The most common re-operation for a recurrent TEF involves repair via a right thoracotomy and use of a flap as interposed tissue between the closure sites. Although several materials have been reported ...
Zamani-Ahmadmahmoodi R - - 2013
Geostatistical studies are used to estimate pollution burden in aquatic ecosystems and to plan large-scale control programs to protect these environments. Geostatistical studies allow us to predicted pollutant concentrations for areas that have not been sampled. This is done by taking into account the spatial correlations between estimated and sampled ...
Groebner Jens - - 2013
BACKGROUND AND METHODS: A liquid crystal display was modified for use inside a 7 T MR magnet. SNR measurements were performed using different imaging sequences with the monitor absent, present, or activated. fMRI with a volunteer was conducted using a visual stimulus. RESULTS AND DISCUSSION: SNR was reduced by 3.7 %/7.9 % in ...
Steindel Frauke - - 2013
Type-1 cannabinoid receptors (CB1) are expressed in different neuronal populations in the mammalian brain. In particular, CB1 receptors on GABAergic or glutamatergic neurons exert different functions and display different pharmacological properties in vivo. This suggests the existence of neuronal type-specific signalling pathways activated by different subpopulations of CB1 receptors. In ...
Perez-Valdespino Abigail - - 2013
AIMS: To isolate and characterize spores superdormant (SD) for germination with either Ca(2+) -dipicolinic acid (CaDPA) or dodecylamine. METHODS AND RESULTS: Bacillus subtilis spores were germinated three times with either CaDPA or dodecylamine and germinated spores removed after each germination treatment, yielding 0.9% (CaDPA-SD spores) or 0.4% (dodecylamine-SD spores) of ...
McCarron Sarah L - - 2013
While tyrosine kinase inhibitor (TKI) therapy is the mainstay of modern management of chronic myeloid leukemia (CML), a significant proportion of CML patients may be refractory or lose their initial response to TKI therapy through a number of cellular and molecular mechanisms of which acquired mutations in the BCR-ABL1 kinase ...
Abd Ghafar Norzana - - 2013
The in vivo quiescent corneal stroma keratocytes need to be transformed to activated state in order to obtain sufficient number of cells either for monolayer evaluation or corneal stroma reconstruction. This study aimed to investigate the phenotypic characterization of corneal stromal cells during culture expansion from the limbal region of ...
Maddumage Ratnasiri - - 2013
In the last 30 years the incidence of kiwifruit allergy has increased with the three major allergenic proteins being identified as actinidin, kiwellin and thaumatin-like protein (TLP). We report wide variation in the levels of actinidin and TLP in 15 kiwifruit varieties from the four most widely cultivated Actinidia species. ...
Tomassone L - - 2013
Abstract A study on tick fauna and tick-borne pathogens was undertaken in Pianosa, an island in the Tuscany Archipelago that constitutes an important stopping and nesting point for migratory birds. Ticks were removed from feral cats and a few terrestrial birds, and host-seeking ticks were collected by dragging. A total ...
Fishelson Lev - - 2013
A comparative study of the reproductive organs in 17 of the 30 species of the tribe Starksiini (Labrisomidae, Blenniiformes) and related labrisomids reveals the major traits of gamete form and production and likely reproductive modes. The testes are of the lobular type and have a testicular gland and sperm ducts. ...
Lu Jeng-Wei - - 2013
Deregulated cell cycle can contribute to the unscheduled proliferation in cancer cells. Overexpression of cell cycle regulators CDK4 and Cyclin D1 has been reported in many cancers. The aim of this study is to determine the clinical implications of CDK4 and Cyclin D1 in hepatocellular carcinoma (HCC). The levels of ...
Kang Lihua - - 2013
Heat shock protein A12B (HSPA12B) is the newest member of a recently defined subfamily of proteins distantly related to the 70-kDa family of heat shock proteins (HSP70) family. HSP70s play a crucial role in protecting cells, tissues, organs and animals from various noxious conditions. Here we studied the dynamic expression ...
Ding Guo-Chun - - 2013
To study the influence of the clay minerals montmorillonite (M) and illite (I), the metal oxides ferrihydrite (F) and aluminium hydroxide (A), and charcoal (C) on soil bacterial communities seven artificial soils with identical texture provided by quartz (Q) were mixed with sterilized manure as organic carbon source before adding ...
Han Su-Xia - - 2013
As a result of the efforts of the Human Genome Project and the rise in demand for molecular diagnostic assays, the development and optimization of novel hybridization probes have focused on speed, reliability, and accuracy in the identification of nucleic acids. Molecular beacons (MBs) are single-stranded, fluorophore-labeled nucleic acid probes ...
Neuman Heather B - - 2013
BACKGROUND: Individuals ≥80 years of age represent an increasing proportion of colon cancer diagnoses. Selecting these patients for elective surgery is challenging because of diminished overall health, functional decline, and limited data to guide decisions. The objective was to identify overall health measures that are predictive of poor survival after elective ...
Yust-Katz Shlomit - - 2013
Leptomeningeal metastasis (LM) most commonly arise from breast and lung cancers, and melanoma. Genitourinary cancer (including ovarian, prostate, uterine kidney and bladder) rarely cause LM, with only case reports published. The aims of the study were to describe cases of patients with Genitourinary cancer and Leptomeningeal metastasis, to estimate its ...
Fürhapter Christina - - 2013
BACKGROUND: An important factor while developing efficient doping prevention strategies is to identify relevant target groups, to evaluate the state of knowledge about this topic as well as to evaluate motivations behind using prohibited substances. Measures to prevent doping substances abuse have to be supported in early stages of childhood. ...
Dong Zhe - - 2013
Acanthosis nigricans (AN) usually correlates to insulin resistance (IR) or obesity in obese populations, but adequate studies on the significance of AN in people with normal body mass index (BMI) have not been performed and discussed. Three hundred and thirty-nine polycystic ovary syndrome (PCOS) patients with normal BMI (<23 kg/m(2) ) ...
Rebibo Lionel - - 2013
INTRODUCTION: Some researchers have suggested that the weight loss of a patient who has undergone bariatric surgery could be influenced by his or her family environment. Indeed, some people decide to undergo surgery after another family member has had the operation. This study aimed to evaluate the results of longitudinal ...
Maes Christa - - 2013
Adequate vascularization is an absolute requirement for bone development, growth, homeostasis, and repair. Endochondral ossification during fetal skeletogenesis is typified by the initial formation of a prefiguring cartilage template of the future bone, which itself is intrinsically avascular. When the chondrocytes reach terminal hypertrophic differentiation they become invaded by blood ...
Liu Quan - - 2013
Abstract Echinococcus granulosus is the causative agent of cystic echinococcosis with medical and veterinary importance worldwide. The aim of this study was to determine the genotype distribution of E. granulosus in animals in Yushu, Qinghai Province, northeastern China. The mitochondrial nicotinamide adenine dinucleotide+hydrogen (NADH) dehydrogenase subunit 1 (nad1) and cytochrome ...
Maurya Anupam - - 2013
Antibacterial activity of lysergol (1) and its semi-synthetic derivatives (2-14) and their synergy with the conventional antibiotic nalidixic acid (NA) against nalidixic acid sensitive (NASEC) and nalidixic acid resistant (NAREC) strains of Escherichia coli was evaluated. Lysergol (1) and derivatives (2-14) did not possess antibacterial activity of their own, but ...
Wu Ning - - 2013
OBJECTIVES: To investigate the prognostic significance of lymph node characteristics (total number of resected lymph nodes, metastatic lymph node ratio, and metastatic lymph nodes site) on survival in patients with esophageal squamous cell carcinoma. METHODS: Patients who underwent esophagectomy at Huashan Hospital, Fudan University, between October 1, 2003, and December ...
Hiroi Shinzo - - 2013
Abstract Background: This study aimed to determine the efficacy and safety of pioglitazone/glimepiride as a fixed-dose combination (FDC) in Japanese patients with type 2 diabetes. Subjects and Methods: In this multicenter, Phase III, open-label evaluation, eligible patients had to have a glycosylated hemoglobin (HbA(1c)) level of ≥7.4% and <10.4% halfway ...
Kim Su Jin - - 2013
PURPOSE: To investigate the effect of the ethanol on corpus cavernosum of the type 2 diabetes mellitus (type 2 DM) rat, since previous studies have reported the positive effect of moderate drinking on type 2 DM and endothelial function. METHODS: Otsuka Long Evans Tokushima Fatty (OLETF, n = 28) and Long Evans ...
Leder Steven B - - 2013
Use of an oral mechanism examination is ubiquitous and long-standing despite a paucity of research supporting its clinical utility in dysphagia diagnostics. The purpose of this study was to investigate whether components of an oral mechanism examination, i.e., binary judgments (complete/incomplete) of labial closure, lingual range of motion, and facial ...
Patel Pranali - - 2013
The ability to reprogram virtually any cell of human origin to behave like embryonic or pluripotent stem cells is a major breakthrough in stem cell biology. Human induced pluripotent stem cells (iPSC) provide a unique opportunity to study "disease in a dish" within a defined genetic and environmental background. Patient-derived ...
Inoue Takeshi - - 2013
ABSTRACT: BACKGROUND: COX-2 inhibitors have an antitumor potential and have been verified by many researchers. Treatment of cancer cells with external stressors such as irradiation can stimulate the over-expression of COX-2 and possibly confer radiation resistance. In this study, we tested if topical diclofenac, which inhibits both COX-1 and COX-2, ...
Liu Jian-Zhong - - 2013
Heat shock proteins such as HSP70 and HSP90 are important molecular chaperones that play critical roles in biotic and abiotic stress responses. However, the involvement of their co- chaperones in stress biology remains largely uninvestigated. In a screen for candidate genes stimulating cell death in soybean (Glycine max), we transiently ...
Xu Chaoyang - - 2013
The purpose of this study was to investigate the expression of Lin28 in gastric carcinoma and to assess its clinical significance. The expression level of Lin28 was assessed by reverse-transcriptase polymerase chain reaction in 10 surgically resected gastric carcinoma and corresponding normal tissues, and by immunohistochemical staining in surgically resected ...
Pham Huong T - - 2013
Ozone-induced dissociation (OzID) is an alternative ion activation method that relies on the gas phase ion-molecule reaction between a mass-selected target ion and ozone in an ion trap mass spectrometer. Herein, we evaluated the performance of OzID for both the structural elucidation and selective detection of conjugated carbon-carbon double bond ...
Kuester Simon K - - 2013
Droplet-based microfluidic systems have become a very powerful tool to miniaturize chemical and biological reactions. However, droplet content analysis remains challenging and relies almost exclusively on optical methods such as fluorescence spectroscopy. Hence, labeling of the analyte is typically required which impedes a more universal applicability of microdroplets. Here we ...
Friedman Samantha - - 2013
Homeownership, a symbol of the American dream, is one of the primary ways through which families accumulate wealth, particularly for blacks and Hispanics. Surprisingly, no study has explicitly documented the segregation of minority owners and renters from whites. Using data from Census 2000, this study aims to fill this gap. ...
Alsemari Abdulaziz - - 2013
Affected patients with hypogonadism have unnaturally low amounts of sex hormones that produce male and female sex characteristics. Males who suffer from this condition lack testosterone, while females fail to produce enough estrogen. Hypogonadism may be present at birth, or it may take effect years later following injury or illness ...
Sjölund-Karlsson Maria - - 2013
Non-Typhi Salmonella cause over 1.7 million cases of gastroenteritis in North America each year, and food-animal products are commonly implicated in human infections. For invasive infections, antimicrobial therapy is indicated. In North America, the antimicrobial susceptibility of Salmonella is monitored by the U.S. National Antimicrobial Resistance Monitoring System (NARMS) and ...
Surmeli-Onay Ozge - - 2013
Feeding intolerance (FI) is usually defined as "gastric residual volume of more than 50 % of the previous feeding volume, emesis, abdominal distension or both of these symptoms and a decrease, delay or discontinuation of enteral feedings." We aimed to compare the incidence of FI in preterm infants fed with powdered ...
Karan-Djurasevic Teodora - - 2013
Dysregulation of apoptosis is a distinctive feature of chronic lymphocytic leukemia (CLL), although a unique mechanism underlying apoptosis resistance of CLL B lymphocytes has not been identified yet. Aberrant expression as well as genetic and epigenetic alterations of numerous genes involved in different pathways of apoptosis regulation has been described ...
Gameiro Paula H - - 2013
Abstract The mushroom Agaricus brasiliensis (sun mushroom), native from the southeast of Brazil, is well known by its medicinal properties that include effects on diabetes, cholesterol levels, and osteoporosis. The antimutagenic effects of A. brasiliensis has been investigated recently and revealed some controversial results depending on the temperature by which ...
Pasi Marco - - 2013
The evaluation of cognitive status is not routine in the acute stroke setting. We aimed to investigate feasibility, applicability, and performances of the Montreal cognitive assessment (MoCA) in acute stroke patients. Consecutive stroke patients (ischemic or hemorrhagic) admitted to one stroke unit were evaluated 5-9 days after stroke with MoCA (score ...
O'Neill Michelle - - 2013
PURPOSE: To review the safety and effectiveness of robot-assisted hysterectomy compared to traditional open and conventional laparoscopic surgery, differentiating radical, simple total with node staging, and simple total hysterectomy. METHODS: Medline, Embase, the Cochrane library, and the Journal of Robotic Surgery were searched for controlled trials and observational studies with ...
Paavilainen Teemu - - 2013
INTRODUCTION: Fabry disease is a rare lysosomal storage disorder leading to cellular accumulation of globotriaosylceramide, especially in blood vessels. It is associated with severe early onset cerebrovascular disease and kidney and heart failure. The purpose of this study was to reveal possible disturbances in white matter integrity in Fabry disease ...
Dai Guiping - - 2013
The association between a single nucleotide polymorphism rs13281615A > G located in the 8q24 and breast cancer risk is still controversial and ambiguous. Hence, we performed a more convincing and precise estimation of the relationship between 8q24 and breast cancer by meta-analyzing the currently available evidence from literature. PubMed, Ovid, Medline, and ...
Bramlage Peter - - 2013
BACKGROUND: Atrial fibrillation (AF) is increasingly prevalent in elderly patients and adversely affects clinical outcomes after coronary artery bypass grafting, non-cardiac surgery or myocardial infarction. Aim of the present analysis was to investigate the prognostic impact of AF in patients undergoing drug eluting stent (DES) implantation during a 1-year follow-up. ...
Bonfá Maricy Raquel Lindenbah - - 2013
Phenol is a toxic aromatic compound used or produced in many industries and as a result a common component of industrial wastewaters. Phenol containing waste streams are frequently hypersaline and therefore require halophilic microorganisms for efficient biotreatment without dilution. In this study three halophilic bacteria isolated from different saline environments ...
Hajducek Dagmar M - - 2013
We consider survival or duration times associated with spells (sojourns in some state) or events experienced by individuals in a population over a specified time period. Duration distributions can be estimated from data recorded during followup of panel members in longitudinal surveys, but adjustments for the sample design, population structure ...
Bulus Hakan - - 2013
BACKGROUND: Acute appendicitis is one of the main pathological conditions requiring emergency surgical intervention. The most widely accepted scoring system is modified Alvarado scoring system (MASS). In this study we aimed to improve the efficiency of MASS by adding a new parameter and to evaluate its efficiency in the diagnosis ...
Pelosi A - - 2013
During 12 weeks, 18 normal dogs were fed a high-caloric diet intended to induce obesity (weight-gain phase). For the next 12weeks (weight-loss phase), all dogs were fed a diet calculated to provide maintenance needs. During this second phase, dogs were randomly assigned to three groups differing only in their exercise ...
Barrett Ann - - 2013
Proanthocyanidins (PACs) and ellagitannins, referred to as "tannins", exist in many plant sources. These compounds interact with proteins due to their numerous hydroxyl groups, which are suitable for hydrophobic associations. It was hypothesized that tannins could bind to the digestive enzymes α-amylase and glucoamylase, thereby inhibiting starch hydrolysis. Slowed starch ...
Khan Fary - - 2013
To examine factors impacting long-term functional outcomes and psychological sequelae in persons with primary brain tumours (BT) in an Australian community cohort. Participants (n = 106) following definitive treatment for BT in the community were reviewed in rehabilitation clinics to assess impact on participants' current activity and restriction in participation, using validated ...
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