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Ojeda-Uribe Mario - - 2013
The use of biological therapies for treating autoimmune diseases is increasing. These therapies are sometimes administered to pregnant women as part of a planned therapeutic regimen or to women with unexpected or unplanned pregnancies. The safety of biological therapies in this setting is a major issue. Here, we describe three ...
Chun Byung-Joon - - 2013
The objective of this study is to determine the efficacy of adding a prokinetic agent to proton pump inhibitors (PPI) for the treatment of laryngopharyngeal reflux (LPR) disease. A prospective, randomized open trial comparing lansoprazole plus itopride to lansoprazole single therapy was performed for 12 weeks. Sixty-four patients with a reflux ...
Tambuyzer Else - - 2013
This study assessed differences between service users', family carers' and mental healthcare providers' perceptions on service user and family carer involvement in mental healthcare. We conducted questionnaires in care networks for persons with serious and persistent mental illness, among 111 service users, 73 family carers and 216 mental healthcare providers. ...
Li Guang-Hu - - 2013
The purpose of this study was to analyze β-catenin and matrix metalloproteinase-2 (MMP-2) expression in non-small cell lung cancer (NSCLC) and to investigate the association between their expression and clinicopathologic characteristics of NSCLC patients. Immunohistochemistry was performed to examine β-catenin and MMP-2 protein expression in 39 resected NSCLC samples and ...
Caruso Rosangela - - 2013
The clinical management of 'difficult' patients is a major challenge which exposes mental health teams to an increased risk of frustration and stress and may lead to professional burnout. The aim of the present study was to investigate whether a cognitive-analytic therapy (CAT) based training undertaken by a mental health ...
Benson Kathleen F - - 2013
Abstract The impact of chronic inflammatory conditions on immune function is substantial, and the simultaneous application of anti-inflammatory and immune modulating modalities has potential for reducing inflammation-induced immune suppression. Sorghum-based foods, teas, beers, and extracts are used in traditional medicine, placing an importance on obtaining an increased understanding of the ...
Cambi Jacopo - - 2013
The aim of this study was to assess the natural course of positional down-beating nystagmus (pDBN) and vertigo in patients with no evidence of central nervous system involvement and of presumed peripheral origin. Fifty-three patients with pDBN had a complete otoneurological examination. All subjects, apart from three (excluded from the ...
Zhu Liang - - 2013
In the course of this study, desorption atmospheric pressure chemical ionization mass spectrometry (DAPCI-MS) was applied to readily acquire the mass spectral fingerprints of camphor wood and other wood samples under ambient conditions. Characteristic natural analytes, such as camphor and geraniol, were successfully detected in their protonated form and successfully ...
de Carvalho Kenia - - 2013
Plant exposure to abiotic stresses leads to an accumulation of reactive oxygen species with the concomitant increase in antioxidant defense mechanisms. Previous studies showed that exogenous application of proline mitigate the deleterious effects caused by oxidative stress due to its ability to increase the activity of antioxidant enzymes. However, there ...
Rozin Ap - - 2013
Felty's syndrome (FS) is characterized by neutropenia and splenomegaly in patients with seropositive (RF+, anti-CCP+) rheumatoid arthritis (RA). As a result of neutropenia, affected persons are increasingly susceptible to infections. In the majority of patients, FS appears in the course of long-standing and well-established RA. Manifestations of FS without clinical ...
Mangia S - - 2013
The results of the study of Xu and colleagues in this issue constitute a critical new piece of information on the functional specialization of astrocytes for K(+) homeostasis in the brain. The relationship between astrocytes and potassium has been long recognized in half a century of research. Now this relation ...
Vaishampayan Ulka - - 2013
Cabozantinib/XL184 (Exelexis, Inc.) has demonstrated remarkable responses in kidney cancer. Preclinical results revealed VEGF, KIT and MET inhibition in a variety of solid tumors such as thyroid, ovarian, renal, lung, liver and prostate cancers. A phase II trial demonstrated efficacy in renal cancer with a 28 % objective response rate, stable ...
Karan-Djurasevic Teodora - - 2013
Dysregulation of apoptosis is a distinctive feature of chronic lymphocytic leukemia (CLL), although a unique mechanism underlying apoptosis resistance of CLL B lymphocytes has not been identified yet. Aberrant expression as well as genetic and epigenetic alterations of numerous genes involved in different pathways of apoptosis regulation has been described ...
Gameiro Paula H - - 2013
Abstract The mushroom Agaricus brasiliensis (sun mushroom), native from the southeast of Brazil, is well known by its medicinal properties that include effects on diabetes, cholesterol levels, and osteoporosis. The antimutagenic effects of A. brasiliensis has been investigated recently and revealed some controversial results depending on the temperature by which ...
Pasi Marco - - 2013
The evaluation of cognitive status is not routine in the acute stroke setting. We aimed to investigate feasibility, applicability, and performances of the Montreal cognitive assessment (MoCA) in acute stroke patients. Consecutive stroke patients (ischemic or hemorrhagic) admitted to one stroke unit were evaluated 5-9 days after stroke with MoCA (score ...
O'Neill Michelle - - 2013
PURPOSE: To review the safety and effectiveness of robot-assisted hysterectomy compared to traditional open and conventional laparoscopic surgery, differentiating radical, simple total with node staging, and simple total hysterectomy. METHODS: Medline, Embase, the Cochrane library, and the Journal of Robotic Surgery were searched for controlled trials and observational studies with ...
Paavilainen Teemu - - 2013
INTRODUCTION: Fabry disease is a rare lysosomal storage disorder leading to cellular accumulation of globotriaosylceramide, especially in blood vessels. It is associated with severe early onset cerebrovascular disease and kidney and heart failure. The purpose of this study was to reveal possible disturbances in white matter integrity in Fabry disease ...
Dai Guiping - - 2013
The association between a single nucleotide polymorphism rs13281615A > G located in the 8q24 and breast cancer risk is still controversial and ambiguous. Hence, we performed a more convincing and precise estimation of the relationship between 8q24 and breast cancer by meta-analyzing the currently available evidence from literature. PubMed, Ovid, Medline, and ...
Bramlage Peter - - 2013
BACKGROUND: Atrial fibrillation (AF) is increasingly prevalent in elderly patients and adversely affects clinical outcomes after coronary artery bypass grafting, non-cardiac surgery or myocardial infarction. Aim of the present analysis was to investigate the prognostic impact of AF in patients undergoing drug eluting stent (DES) implantation during a 1-year follow-up. ...
Bonfá Maricy Raquel Lindenbah - - 2013
Phenol is a toxic aromatic compound used or produced in many industries and as a result a common component of industrial wastewaters. Phenol containing waste streams are frequently hypersaline and therefore require halophilic microorganisms for efficient biotreatment without dilution. In this study three halophilic bacteria isolated from different saline environments ...
Hajducek Dagmar M - - 2013
We consider survival or duration times associated with spells (sojourns in some state) or events experienced by individuals in a population over a specified time period. Duration distributions can be estimated from data recorded during followup of panel members in longitudinal surveys, but adjustments for the sample design, population structure ...
Galliot Emmanuel - - 2013
This study investigated the brain areas involved in episodic memory retrieval of pictures depending on the characteristics of the contextual environment during encoding (i.e. presence or absence of an odor). In the first stage, subjects were presented with a series of 32 pictures. Half of the pictures were presented while ...
Zhang Qichun - - 2013
Nitrogen (N) losses from agricultural fields have been extensively studied. In contrast, surface runoff and N losses have rarely been considered for bamboo forests that are widespread in regions such as southern China. The thriving of bamboo industries has led to increasing fertilizer use in bamboo forests. In this study, ...
Seki Masafumi - - 2013
Multidrug-resistant Pseudomonas aeruginosa (MDRP) is a major problem among hospital-acquired infections. We had a one-month outbreak of this strain at a university hospital in Osaka, Japan, from May to June 2004. To determine the cause of the outbreak, we collected and analyzed epidemiological information about the patients from whom MDRP ...
Petrauskas Vytautas - - 2013
Volume changes that accompany protein unfolding and ligand binding are important but largely neglected thermodynamic parameters that may facilitate rational drug design. Here, we determined the volume of lead compound ICPD47 binding to an anticancer target, heat shock protein 90 N-terminal domain, using a pressure shift assay (PressureFluor). The ligand ...
Ngo J T - - 2013
BACKGROUND: Anaerobes are a relatively uncommon but important cause of bloodstream infection. However, their epidemiology has not been well defined in non-selected populations. We sought to describe the incidence of, risk factors for, and outcomes associated with anaerobic bacteremia. METHODS: Population-based surveillance for bacteremia with anaerobic microorganisms was conducted in ...
Cheng Rubin - - 2013
Malonyl-CoA:acyl-carrier protein transacylase (MCAT), which transfers the malonyl group from malonyl-CoA to holo-acyl carrier protein (ACP), is a key enzyme in fatty acid biosynthesis. Schizochytrium sp. TIO1101 is a marine protist with high levels of docosahexaenoic acid accumulation. In this study, the putative fabD gene coding MCAT was isolated from ...
Bakhtiar Mehdi - - 2013
In this study, we report normative data by native Persian speakers for concept familiarity, age of acquisition (AoA), imageability, image agreement, name agreement, and visual complexity, as well as values for word frequency, word length, and naming latency for 200 of the colored Snodgrass and Vanderwart (Journal of Experimental Psychology: ...
Daram Sumanth R - - 2013
BACKGROUND: Through-the-scope (TTS) endoscopic clipping devices are widely used. No benchtop testing or direct comparisons of these endoclips have been performed to show their rotational ability and inherent mechanical strengths during closure and after deployment. This study aimed to provide benchtop data that can be used to guide clinical applications ...
Macionis Valdas V Clinic of Rheumatology, Orthopedics and Traumatology, and Reconstructive Surgery, Vilnius University Faculty of Medicine, Vilnius, Lithuania. - - 2013
While "diagrammatic" evaluation of finger joint angles using two folded paper strips as goniometric arms has been proposed and could be an alternative to standard goniometry and a means for self-evaluation, the measurement differences and reliability are unknown. This study assessed the standard and diagrammatic finger goniometry performed by an ...
Gozalan Aysegul A Refik Saydam National Public Health Agency, Ankara, Turkey. - - 2013
This study was carried out to better understand the epidemiology of hantaviruses in a province of Turkey (Giresun) where human hantavirus disease has recently been detected. In this cross-sectional study, a total of 626 blood samples from healthy people aged 15 and 84 years old were collected both in urban ...
Wigal Sharon B - - 2013
Abstract Objective: The purpose of this study was to determine the efficacy of NWP06, a novel extended-release (ER) liquid formulation of methylphenidate (MPH), compared with placebo in the treatment of attention-deficit/hyperactivity disorder (ADHD) in children in a laboratory school. Methods: A total of 45 subjects ages 6-12 years were enrolled ...
Pamuk Ferda - - 2013
Background: Aim of this study was to compare gingival changes induced by short and long term tacrolimus and nifedipine administration alone or in combination and to evaluate the expression levels of tumor suppressor phosphatase and tensin homolog (PTEN) in drug-induced gingival enlargement. Methods: Eighty rats were equally divided into eight ...
Masclaux Frederic G - - 2013
Pigs are very often colonized by Staphylococcus aureus and transmission of such pig-associated S. aureus to humans can cause serious medical, hygiene, and economic problems. The transmission route of zoonotic pathogens colonizing farm animals to humans is not well established and bioaerosols could play an important role. The aim of ...
Ong Elodie - - 2013
Infective endocarditis represents a classical contra-indication to thrombolysis for acute ischemic stroke due to a potential increased risk of intracranial hemorrhage. However, some case reports have suggested safety and potential efficacy of intravenous or intra-arterial thrombolysis in stroke related to infective endocarditis. We present a case of ischemic stroke related ...
Li Bing - - 2013
Laparoscope-assisted diagnosis and treatment of Amyand's hernia in children are rarely reported in literature. We report our preliminary experiences to emphasize the advantages and feasibility of this procedure in six cases. Laparoscope-assisted diagnosis and treatment of Amyand's hernias in six children from October 2010 to February 2012 were performed. A ...
Dunne Eileen F - - 2013
PURPOSE: Two human papillomavirus (HPV) vaccines are available to prevent cervical cancer. One early measure of HPV vaccine impact would be a reduction in vaccine-related HPV types (HPV 6, 11, 16, or 18, or HPV 16, 18) in cervical samples from young women. We aimed to assess feasibility of specimen ...
Herzig Shoshana J SJ Division of General Medicine and Primary Care, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA. - - 2013
It is unknown whether there exist certain subsets of patients outside of the intensive care unit in whom the risk of nosocomial gastrointestinal bleeding is high enough that prophylactic use of acid-suppressive medication may be warranted. To identify risk factors for nosocomial gastrointestinal bleeding in a cohort of non-critically ill ...
Scaglione Francesco - - 2013
New oral anticoagulants (OACs) that directly inhibit Factor Xa (FXa) or thrombin have been developed for the long-term prevention of thromboembolic disorders. These novel agents provide numerous benefits over older vitamin K antagonists (VKAs) due to major pharmacological differences. VKAs are economical and very well characterized, but have important limitations ...
Servan-Mori Edson - - 2013
To identify and analyze the factors associated with the decision of migrants suffering violence while in transit through Mexico, to continue on their trip or turn back. Cross-sectional study combining quantitative and qualitative analyses. Socio-demographic and health characteristics, as well as types of violence and factors associated with the decision ...
Nuttall Tim - - 2013
Tim Nuttall discusses some factors to consider when interpreting the results of antimicrobial susceptibility tests.
Ferreira Gilson Rodrigues - - 2013
In this study, Raman, infrared, UV/Vis, NMR and single crystal X ray diffraction spectroscopies are used to elucidate the tautomeric equilibrium of azo dyes derived from 1-phenyl-azo-2-naphthol (Sudan I). A new crystallographic structure is described for Sudan I revealing the presence of intramolecular hydrogen bonds and supramolecular interactions, such as ...
Karavasilis Vasilios - - 2013
We undertook this phase I study to investigate the feasibility of the combination of temozolomide (TMZ) and lapatinib (LP) and to define the maximum tolerated dose (MTD) of LP in patients with relapsed high-grade gliomas. Eligible patients were enrolled in this dose escalation study of LP. TMZ was administered at ...
Wong P - - 2013
Thalassemia bone disease is well described, but the prevalence of nephrolithiasis has not been characterized. The association between nephrolithiasis, reduced bone density, and increased fractures has been demonstrated through this retrospective study of 166 participants with transfusion-dependent thalassemia. The findings support the need for increased vigilance of kidney and bone ...
Renault P E - - 2013
Alcoholic fermentation of grape must is a complex process, involving several yeast genera and species. The early stages in fermentation are dominated by non-Saccharomyces yeasts that are gradually replaced by the Saccharomyces cerevisiae species, which takes over the fermentation. Quantitative studies have reported the influence of non-Saccharomyces yeast species on ...
Oleinik Anton - - 2013
Scientific communication takes place at two registers: first, interactions with colleagues in close proximity-members of a network, school of thought or circle; second, depersonalised transactions among a potentially unlimited number of scholars can be involved (e.g., author and readers). The interference between the two registers in the process of peer ...
Karkouche R - - 2013
Renal lymphangiomatosis is an extremely rare disease characterized by developmental malformation of the lymphatic system surrounding the kidneys. We present the case of a 22-year-old pregnant female discovered because of worsening. Ultrasound, computed tomography, and magnetic resonance imaging studies were performed. An 18 × 11 × 10 cm voluminous cystic subcapsular lesion compressing the left ...
Horneff Gerd - - 2013
The development of biologics has markedly changed the treatment of JIA. Complete control of the disease and remission has today become the main goal of treatment preventing long-term damage and disability. This review gives an overview of the current treatment options using biologics in JIA. The biologic drugs are discussed ...
Mechelke Martin - - 2013
Protein chemical shifts encode detailed structural information that is di_cult and computationally costly to describe at a fundamental level. Statistical and machine learning approaches have been used to infer correlations between chemical shifts and secondary structure from experimental chemical shifts. These methods range from simple statistics such as the chemical ...
Hirata Akira - - 2013
PURPOSE: We produced a simulated eye for vitreous surgery training by using Japanese quail eggs, and verified its utility. METHODS: We used a special cutter to cut off the sharp end of a Japanese quail egg, fitted a silicone simulated sclerocorneal cap to the exposed area, and fixed the egg ...
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