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Results 601 - 650 of 3975
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Weir Brad - - 2013
We introduce an implicit method for state and parameter estimation and apply it to a stochastic ecological model. The method uses an ensemble of particles to approximate the distribution of model solutions and parameters conditioned on noisy observations of the state. For each particle, it first determines likely values based ...
Kreeftmeijer-Vegter Annemarie Rosan - - 2013
Objective: To develop an oral solid dosage form of levamisole suitable for the paediatric population in terms of dose accuracy, palatability, stability and ease of administration. Methods: Small undividable tablets (Ø5 - 8 mm) in four different strengths were manufactured to allow for flexible and accurate dosing. In vitro dissolution ...
Han Lianhuan - - 2013
Substrate leveling is an essential but neglected instrumental technique of scanning electrochemical microscopy (SECM). In this technical note, we provide an effective substrate leveling method based on the current feedback mode of SECM. By using an air-bearing rotary stage as the supporter of electrolytic cell, the current feedback presents a ...
Erthal Vanessa - - 2013
Laser acupuncture is a modality of low-level light therapy used as an alternative to needling for the past three decades. Although it has proved effective for the treatment of various conditions, the mechanisms underlying its effects are not fully understood. To contribute to this understanding, this study was designed to ...
Mantel Frederick - - 2013
ABSTRACT: Although locoregional relapse is frequent after definitive radiotherapy (RT) or multimodal treatments, re-irradiation is only performed in few patients even in palliative settings like e.g. vertebral metastasis. This is most due to concern about potentially severe complications, especially when large volumes are exposed to re-irradiation. With technological advancements in ...
Kim Sunghoon - - 2013
Evaluation of gap length is an important part of preoperative assessment of esophageal atresia (EA) without distal tracheoesophageal fistula. A technique of measuring the esophageal gap in isolated EA using carbon dioxide gas insufflation of the stomach through a port and a laparoscope is described.
Mustafa Ayman G - - 2013
PURPOSE: The study aims to investigate anatomy learning styles and strategies of Jordanian and Malaysian medical students at the Jordan University of Science and Technology. METHODS: The study is a cross-sectional questionnaire-based study. Students' responses for the questionnaire were numerically coded, and the results were analyzed to reveal statistically significant ...
Fernandes Ricardo J - - 2013
Pinna et al. (J Physiol Sci, 10.1007/s12576-012-0226-7, 2012) showed that a tethered swimming incremental protocol leads to higher maximal oxygen consumption values than during cycle ergometer and arm-crank tests, and evidenced that anaerobic threshold occurred at higher workloads during swimming comparing to other types of exercise. This is an interesting ...
- - 2013
The following information has been produced for Veterinary Record by the Veterinary Medicines Directorate (VMD) to provide an update for veterinary surgeons on recent changes to marketing authorisations for veterinary medicines in the UK and on other relevant issues.
Winter Corinna C - - 2013
BACKGROUND: While research on exercise interventions during anticancer treatment is well-established in adults, only very few studies exist in children. However, pediatric patients experience great limitations to being physically active, and appropriate interventions are desired. PROCEDURE: The present study aimed at investigating the effects of individualized exercise interventions during inpatient ...
Kiriukhin Michael - - 2013
AIMS: To engineer acetogen biocatalyst selectively overproducing ethanol from synthesis gas or CO(2) /H(2) as the only liquid carbonaceous product. METHODS AND RESULTS: Ethanol-resistant mutant originally capable of producing only acetate from CO(2) /CO was engineered to eliminate acetate production and spore formation using our proprietary Cre-lox66/lox71-system. Bi-functional aldehyde/alcohol dehydrogenase ...
Spaander Manon C W - - 2013
BACKGROUND & AIMS: It remains unclear when anticoagulant therapy should be given in patients with non-cirrhotic portal vein thrombosis (PVT). Aim of this study was to assess the effect of anticoagulation on recurrent thrombotic events and gastrointestinal bleeding in non-cirrhotic PVT patients. METHODS: Retrospective study of all patients with non-cirrhotic ...
Schmidt Matthieu - - 2013
PURPOSE: This study was designed to optimize the latest generation venovenous (vv)-extracorporeal membrane oxygenation (ECMO)-circuit configuration and settings based on the evaluation of blood oxygenation and CO(2) removal determinants in patients with severe acute respiratory distress syndrome (ARDS) on ultraprotective mechanical ventilation. METHODS: Blood gases and hemodynamic parameters were evaluated ...
Kako Hiromi - - 2013
Neuroblastomas are the most common, non-central nervous system tumor of childhood. Similar to pheochromocytomas, they are derived from neural crest cells and therefore retain the potential to synthesize catecholamines. Unlike pheochromocytomas, however, perioperative issues related to blood pressure instability with hypertension are uncommon. We report details of a 3-year-old child ...
Goryakin Yevgeniy - - 2013
This paper examines for the first time the consequences of ill health on labour supply for a sample of nine countries from the former Soviet Union (FSU), using a unique multicountry household survey specifically designed for this region. We control for a wide range of individual, household, and community factors, ...
Origone P - - 2013
PURPOSE: Gastrointestinal stromal tumors (GISTs) are mesenchymal tumors of the gastrointestinal tract. Most (80 %) contain activating mutations in the KIT receptor tyrosine kinase, roughly 10 % in platelet-derived growth factor receptor-alpha (PDGFRA). In a small subset, BRAF mutations are an alternative molecular pathway. GISTs respond well to imatinib, but low response ...
Buchs Nicolas C - - 2013
BACKGROUND: Courses, including lectures, live surgery, and hands-on session, are part of the recommended curriculum for robotic surgery. However, for general surgery, this approach is poorly reported. The study purpose was to evaluate the impact of robotic general surgery course on the practice of participants. METHODS: Between 2007 and 2011, ...
Meng Xinzhu - - 2013
With increasing fishing pressures having brought several stocks to the brink of collapse, there is a need for developing efficient harvesting methods that account for factors beyond merely yield or profit. We consider the dynamics and management of a stage-structured fish stock. Our work is based on a consumer-resource model ...
Vannatta Seth - - 2013
In this paper we (1) define and describe the practice of narrative medicine, (2) reveal the need for narrative medicine by exposing the presuppositions that give rise to its discounting, including a reductive empiricism and a strict dichotomy between scientific fact and narrative value, (3) show evidence of the effects ...
Hirata Akira - - 2013
PURPOSE: We produced a simulated eye for vitreous surgery training by using Japanese quail eggs, and verified its utility. METHODS: We used a special cutter to cut off the sharp end of a Japanese quail egg, fitted a silicone simulated sclerocorneal cap to the exposed area, and fixed the egg ...
Pal Somedatta - - 2013
The microscopic dynamic properties of water molecules present in the vicinity of a protein is expected to be sensitive to its local conformational motions and the presence of polar and charged groups at the surface capable of anchoring water molecules through hydrogen bonds. In this work, we attempt to understand ...
Zhang Ji-Yi - - 2013
Switchgrass (P. virgatum L.) is a perennial C4 grass with potential to become a major bioenergy crop. To help realize this potential, a set of RNA-based resources were developed. Expressed sequence tags (ESTs) were generated from two tetraploid switchgrass genotypes, Alamo AP13 and Summer VS16. Over 11.5 million high-quality ESTs ...
Debergh Isabelle - - 2013
A Bochdalek hernia is a rare type of diaphragmatic defect, generally presenting in early childhood with acute signs of cardiorespiratory distress. We herein report a case of acute abdomen in a pregnant patient with pain increasing when lying on her right side. Laparoscopic evaluation revealed a right-sided Bochdalek hernia with ...
Okur Erdogan - - 2013
The aim of our study is to evaluate the status of selenium and zinc in nasal polyp tissues and to investigate the possible role of trace elements and antioxidants including superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) in nasal polyps. In this study, the antioxidant enzyme and trace element levels ...
Suda Kentaro - - 2013
Although somatostatin analogues are effective medical therapy for acromegaly, the serum insulin-like growth factor-I (IGF-I) levels remain uncontrolled in 35% of patients. Combined therapy with octreotide LAR and cabergoline has been reported to normalize IGF-I levels in 42-56% of Caucasian patients with acromegaly. However, it remains to be clarified whether ...
Ebata Shingo - - 2013
A new system incorporating a multi-turn time-of-flight secondary ion/sputtered neutral mass spectrometer (TOF-SIMS/SNMS) with laser post-ionization was designed and constructed. This system consists of a gallium focused ion beam, femtosecond (fs) laser for post-ionization, and multi-turn TOF mass spectrometer. When laser post-ionization was used, the secondary ion signal strengths for ...
Bonilla-Abadía F - - 2013
We report an adult female patient with Takayasu arteritis (TA) receiving conventional medical treatment and anti-TNF therapy, which developed progressive thoracic and abdominal aortic aneurysms. She developed imminent rupture of the thoracic aneurysm and an endovascular stent-graft (EVSG) was emergency implanted and a year after this procedure the abdominal aneurysm ...
White Hayden - - 2013
PURPOSE: Although glucose is the main source of energy for the human brain, ketones play an important role during starvation or injury. The purpose of our study was to investigate the metabolic effects of a novel hypertonic sodium ketone solution in normal animals. METHODS: Adult Sprague-Dawley rats (420-570 g) were divided ...
Oshiumi Hiroyuki - - 2013
Acute hepatitis C virus (HCV) infection evokes several distinct innate immune responses in host, but the virus usually propagates by circumventing these responses. Although a replication intermediate double-stranded RNA is produced in infected cells, type I interferon (IFN) induction and immediate cell death are largely blocked in infected cells. In ...
McAndrew J - - 2013
BACKGROUND: In terms of eradication, osteomyelitis represents one of the most challenging infective conditions in medicine and surgery. In recent years, the use of bioactive glass in conjunction with antimicrobial therapy has emerged as a viable new treatment. AIM: We present a short study, from a regional orthopaedic unit, demonstrating ...
Uzuka Takeshi - - 2013
OBJECTIVE: Early thrombosed aortic dissection is a form of aortic dissection and includes the condition called aortic intramural hematoma. It was generally considered as surgical emergency. However, the optimal treatment strategy for acute type A intramural hematoma is becoming controversial after recent studies indicated more benign clinical course for this ...
- - 2013
A new year, a new start, a new me! Jen Hall makes a lasting New Year's resolution.
Koçak Erdem - - 2013
AIM: Gastric cancer can present as a gastric ulcer, which can mimic a benign gastric ulcer. In this study, we aimed to investigate the value of gastric ulcer size and location in the differential diagnosis of benign and malignant gastric ulcers. METHODS: We reviewed retrospectively the upper endocopic findings of ...
Zocevic Aleksandar - - 2013
Abstract In malaria, mosquito saliva and salivary glands play central roles in the multi-faceted interactions that occur among the parasite, its vector, and its host. Analyzing the processes involved in the survival and maintenance of the Plasmodium parasite in mosquito organs, and in its transmission into vertebrate hosts, may lead ...
Neupane Subas - - 2013
This study investigated risk factors associated with the type of birth attendants and timing of postnatal care among a nationally representative sample of Nepalese women. The 2006 Nepalese Demographic and Health Survey on women age 15-49 years old who had delivered within 3 years prior to the survey (N = 4,136) was used. Multivariate ...
Hellal Kort Ymene - - 2013
ABSTRACT: BACKGROUND: Genotype analyses of avian reoviruses isolated from organ samples collected from chickens with suspicious clinical symptoms, between 1997--2008, was based on sequences for both sigmaC and sigmaB genes and aligned with those published in the Genbank, making it possible to carry out studies of molecular classification and relationships. ...
Bozkurt Sureyya - - 2013
Additional chromosomal abnormalities (ACAs) in Philadelphia chromosome (Ph)-positive chronic myeloid leukemia (CML) are strongly associated with disease progression, but their prognostic impact and effect on treatment response are not clear. While the onset of ACAs in Ph-negative cells during treatment has been described, their origin and clinical significance remain to ...
Goloborodko Anton A - - 2013
Pyteomics is a cross-platform, open-source Python library providing a rich set of tools for MS-based proteomics. It provides modules for reading LC-MS/MS data, search engine output, protein sequence databases, theoretical prediction of retention times, electrochemical properties of polypeptides, mass and m/z calculations, and sequence parsing. Pyteomics is available under Apache ...
Geerdes-Fenge H F - - 2013
BACKGROUND: Whether antibiotic treatment in patients with enterohemorrhagic Escherichia coli (EHEC)-associated diarrhea influences the risk of hemolytic uremic syndrome (HUS) has still to be elucidated. PATIENTS AND METHODS: During the EHEC epidemic which occurred in northern Germany in spring 2011, 24 patients with E. coli O104:H4 infection were treated at ...
Schuster Christopher F - - 2013
Toxin-antitoxin (TA) systems are small genetic elements found on plasmids or chromosomes of countless bacteria, archaea and possibly also unicellular fungi. Under normal growth conditions the activity of the toxin protein or its translation is counteracted by an antitoxin protein or non-coding RNA. Five types of TA systems have been ...
Donatsky Anders Meller - - 2013
BACKGROUND: One of the biggest concerns associated with transgastric surgery is contamination and risk of intra-abdominal infection with microbes introduced from the access route. The purpose of this study was to evaluate the effect of oral decontamination with chlorhexidine on microbial contamination of the endoscope. METHODS: In a prospective, randomized, ...
Mavri Ana - - 2013
Campylobacter are the most commonly reported bacterial causes of human gastroenteritis, and they are becoming increasingly resistant to antibiotics, including macrolides and fluoroquinolones, those most frequently used for the treatment of campylobacteriosis. Active efflux mechanisms are involved in resistance of Campylobacter to a broad spectrum of antimicrobials, and are also ...
Yıldız Selda - - 2013
Inversion injuries of the ankle are the most common sport injuries. Extreme inversion of the ankle affects frequently lateral ankle ligaments, especially the anterior talofibular and calcaneofibular ligaments. The aim of this study is to investigate the ligaments in detail to contribute to accurate evaluation of radiological investigations and more ...
Allegaert Karel - - 2013
Drug therapy is a very powerful tool to improve the medical outcome of children. Despite this fact, pediatricians still commonly prescribe drug formulations that were developed for adults. In this series of educational papers related to pediatric clinical pharmacology, we aim to raise awareness on different aspects of clinical pharmacology ...
Rubel Diana - - 2013
Atopic dermatitis (AD) is a relatively common disease in patients in the Asia-Pacific region. It presents a particular clinical challenge and requires careful clinical management. The chronic nature of AD characterized by flares, exacerbations and periods of quiescence requires a multipronged approach aimed at reducing itch, inflammation and the appearance ...
Zhang Huiyong - - 2013
MicroRNAs (miRNAs) are endogenous small RNAs repressing target gene expression post-transcriptionally and are critically involved in various development processes and responses to environmental stresses. MiR408 is highly conserved in land plants and targets several transcripts encoding copper proteins. Although it has been well documented that expression level of miR408 is ...
Huelle Jan O - - 2013
BACKGROUND: To evaluate accuracy of WASCA wavefront aberrometry (WA) refraction in comparison to manifest refraction (MR) in an older population awaiting cataract surgery. METHODS: Prospectively, refractive errors of 130 eyes were determined by WA and MR. Mean age was 65.9 (SD 11.81), corrected distance visual acuity (CDVA) averaged 0.20 logMar ...
Van Nguyen Julie My - - 2013
Sudden infant death syndrome (SIDS) is the leading cause of death among infants aged 1 to 12 months. In this article, we review risk factors that may predispose infants to increased vulnerability. Maternal characteristics, including nonmodifiable and modifiable factors, antenatal medical conditions, labor and delivery events, and infant characteristics, are ...
Esrafilian Amir - - 2013
The effect of knee OA on kinetic and kinematic parameters during walking and standing is still controversial. Stability and energy consumption have not been well investigated in patients with OA. This research investigated the parameters distinguishing between the healthy subjects and patients with OA performance. It also examined the differences ...
Amor Antonio - - 2013
BACKGROUND: Despite obesity being closely associated with two common risk factors for albuminuria, namely type 2 diabetes mellitus (T2DM) and hypertension, information on the impact of weight loss on albumin excretion rate in morbidly obese (MO) subjects is scarce. OBJECTIVE: To evaluate the independent contribution of weight loss following bariatric ...
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