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Results 551 - 600 of 3975
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Nikolaou Georgios - - 2013
Epistaxis is a very common ENT event. Apart from the effectiveness of the different treatment options, the discomfort and the financial burden are of great importance. It has been the aim of this study to obtain data regarding the discomfort/pain of the epistaxis treatments and to calculate the financial burden. ...
Marotti Gastone - - 2013
Collagen texture and osteocyte distribution were analyzed in human woven- and lamellar-bone using scanning and transmission electron microscopy. We provide data substantiating the concept that lamellar bone is made up of an alternation of dense-acellular lamellae and loose-cellular lamellae, all exhibiting an interwoven texture of collagen fibers. An attempt is ...
Oberaigner Willi - - 2013
BACKGROUND: Immigration plays a major role in obstetrics in Austria, and about 18 % of the Austrian population are immigrants. Therefore, we aimed to (1) test the feasibility of a proposed questionnaire for assessment of migrant status in epidemiological research and (2) assess some important associations between procedures and outcomes in ...
Niemeyer Julia - - 2013
The dominant tobacco mosaic virus (TMV) resistance gene N confers a hypersensitive response (HR) at the site of TMV infection and protects tobacco against systemic spread of the virus. To study N gene activity in seeds and early seedling development, the avirulence gene of N, the helicase domain (p50) of ...
Nett Randall J - - 2013
Abstract Background: Coxiella burnetii is an endemic bacterial pathogen in the United States and the causative agent of Q fever. Two outbreaks of Q fever occurred in Montana during 2011, which led to the issuance of a health alert urging clinicians to test patients with Q fever-compatible illnesses for C. ...
Ngo J T - - 2013
BACKGROUND: Anaerobes are a relatively uncommon but important cause of bloodstream infection. However, their epidemiology has not been well defined in non-selected populations. We sought to describe the incidence of, risk factors for, and outcomes associated with anaerobic bacteremia. METHODS: Population-based surveillance for bacteremia with anaerobic microorganisms was conducted in ...
Cheng Rubin - - 2013
Malonyl-CoA:acyl-carrier protein transacylase (MCAT), which transfers the malonyl group from malonyl-CoA to holo-acyl carrier protein (ACP), is a key enzyme in fatty acid biosynthesis. Schizochytrium sp. TIO1101 is a marine protist with high levels of docosahexaenoic acid accumulation. In this study, the putative fabD gene coding MCAT was isolated from ...
Bakhtiar Mehdi - - 2013
In this study, we report normative data by native Persian speakers for concept familiarity, age of acquisition (AoA), imageability, image agreement, name agreement, and visual complexity, as well as values for word frequency, word length, and naming latency for 200 of the colored Snodgrass and Vanderwart (Journal of Experimental Psychology: ...
Daram Sumanth R - - 2013
BACKGROUND: Through-the-scope (TTS) endoscopic clipping devices are widely used. No benchtop testing or direct comparisons of these endoclips have been performed to show their rotational ability and inherent mechanical strengths during closure and after deployment. This study aimed to provide benchtop data that can be used to guide clinical applications ...
Wigal Sharon B - - 2013
Abstract Objective: The purpose of this study was to determine the efficacy of NWP06, a novel extended-release (ER) liquid formulation of methylphenidate (MPH), compared with placebo in the treatment of attention-deficit/hyperactivity disorder (ADHD) in children in a laboratory school. Methods: A total of 45 subjects ages 6-12 years were enrolled ...
Pamuk Ferda - - 2013
Background: Aim of this study was to compare gingival changes induced by short and long term tacrolimus and nifedipine administration alone or in combination and to evaluate the expression levels of tumor suppressor phosphatase and tensin homolog (PTEN) in drug-induced gingival enlargement. Methods: Eighty rats were equally divided into eight ...
- - 2013
The BVA officer team and representatives from the Northern Ireland veterinary associations met recently in Belfast to finalise the formation of a BVA Northern Ireland Branch.
Zhang Jinchao - - 2013
The effects of Mn(2+) on the proliferation, osteogenic and adipogenic differentiation of BMSCs were evaluated by employing MTT, ΔΨm, cell cycle, ALP activity, collagen production, ARS and oil red O stain assays. The results indicated that Mn(2+) decreased the viability at most concentrations for 24 h, but the viability was increased ...
Saravanan Vijayakumar - - 2013
Abstract Chloroplasts are organelles found in plant system and other photosynthetic eukaryotes. Since a large number of essential pathways take place in this organelle, proteins in the chloroplast are considered vital. Therefore, knowledge about the subchloroplast localization of the chloroplast proteins will provide precise information in understanding its interaction within ...
Heredia-Jimenez Jose M - - 2013
The aim of this study was to assess the kinematics disorder of gait in men with fibromyalgia. We studied 12 male with fibromyalgia and 14 healthy men. Each participant of the study walked five trials along a 18.6-m walkway. Fibromyalgia patients completed a Spanish version of Fibromyalgia Impact Questionnaire. Significant ...
Nakajima Kiyokazu - - 2013
BACKGROUND: Use of rigid instruments via transvaginal (TV) route has been proposed as a practical alternative to natural orifice translumenal endoscopic surgery (NOTES) using flexible devices. However, its safety has not been fully evaluated for each abdominal organ with different positional relationship to the vagina. The aim of this study ...
de Melo Jociana Bandeira - - 2013
The aim of the present study was to investigate the in vitro effect of CO(2) laser on the inhibition of root surface demineralization around composite resin restorations. For this purpose, 30 blocks obtained from human molar roots were divided into three groups: group 1 (negative control), cavity prepared with cylindrical ...
Raiborg Camilla - - 2013
Endocytosis and subsequent membrane traffic through endosomes are cellular processes that are integral to eukaryotic evolution, and numerous human diseases are associated with their dysfunctions. Consequently, it is important to untangle the molecular machineries that regulate membrane dynamics and protein flow in the endocytic pathway. Central in this context is ...
Ayers Catherine - - 2013
This study presents the perspectives of academic-VA partners who have recently completed a randomized clinical trial within a VA outpatient clinic. The authors reflect on the challenges and rewards of implementing academic-VA community clinical research partnerships with the aim of assisting new VA investigators and VA collaborators. Staff resistance, time ...
Vamanu Emanuel - - 2013
Abstract The antioxidant and antimicrobial properties of two edible mushrooms (Pleurotus ostreatus PBS281009 and Coprinus comatus M8102) were evaluated in this study. The mycelium ethanolic extract obtained in the presence of four different nitrogen sources was investigated with regard to their production of phenolic compounds, β-carotene, lycopene, and their antimicrobial ...
Bian Ruixin - - 2013
By carrying out density functional theory (DFT) calculations, we have studied the effects of silicon (Si)-doping on the geometrical and electronic properties, as well as the chemical reactivity of carbon nanotubes (CNTs). It is found that the formation energies of these nanotubes increase with increasing tube diameters, indicating that the ...
Deleavey Glen F - - 2013
Small interfering RNAs (siRNAs) can trigger potent gene silencing through the RNA interference (RNAi) pathway. The RNA-induced silencing complex (RISC) is key to this targeted mRNA degradation, and the human Argonaute2 (hAGO2) endonuclease component of RISC is responsible for the actual mRNA cleavage event. During RNAi, hAGO2 becomes loaded with ...
Singh Shailendra - - 2013
Calculations of withdrawal time (WT) should be based on colonoscopies where no intervention is performed. Inclusion of procedures with interventional maneuvers, such as polypectomy or biopsy, for estimation of WT can lead to measurement bias and affect the validity of the study.
Hellerbrand Claus - - 2013
Hepatic stellate cells (HSCs) are pericytes of liver in the space between parenchymal cells and sinusoidal endothelial cells of the hepatic lobule. HSCs comprise specialized functions such as vitamin A storage, hemodynamic functions, support of liver regeneration, and immunoregulation. In pathological conditions, HSCs transform to an activated myofibroblasts-like phenotype, start ...
Silva Valter - - 2013
Abstract In 2009, important health organizations met to construct a Joint Scientific Statement (JSS) intended to harmonize the diagnosis of metabolic syndrome worldwide. The JSS aimed to unify the diagnostic criteria of metabolic syndrome, particularly in relation to whether to include abdominal obesity as a criterion of diagnosis. A large ...
Natorska J - - 2013
BACKGROUND: A role of fibrinolysis in the pathogenesis of AS is unknown, although fibrinolytic proteins have been detected in aortic stenotic valves. OBJECTIVE: To investigate whether impaired fibrinolysis could be associated with aortic valve stenosis (AS). METHODS AND RESULTS: We studied 74 patients with AS (43M, 31F, aged 62.7±10.7 years) ...
Lu Yongping - - 2013
In this study, we aimed to prepare a neovascularization-relevant inflammatory cytokine-targeted ultrasound contrast agent and apply it in the ultrasound imaging of atherosclerotic plaque. An interleukin-8 (IL-8) monoclonal antibody was conjugated to SonoVue microbubbles using the N-succinimidyl-3-(2-pyridyldithio)propionate cross-linking method. Then, a prepared IL-8-targeted contrast agent was used for contrast-enhanced ultrasound ...
Demarco Ricardo Cassiano - - 2013
The Cilia represent one of the main mechanisms contributing to the clearance of microorganisms and particles from the respiratory epithelium. Primary ciliary dyskinesia (PCD) is a genetically determined disorder characterized by irreversible systemic dysmotility of the cilia. Secondary ciliary dyskinesia (SCD) differs from primary defects on the reversible ultrastructural alterations ...
Mangia S - - 2013
The results of the study of Xu and colleagues in this issue constitute a critical new piece of information on the functional specialization of astrocytes for K(+) homeostasis in the brain. The relationship between astrocytes and potassium has been long recognized in half a century of research. Now this relation ...
Vaishampayan Ulka - - 2013
Cabozantinib/XL184 (Exelexis, Inc.) has demonstrated remarkable responses in kidney cancer. Preclinical results revealed VEGF, KIT and MET inhibition in a variety of solid tumors such as thyroid, ovarian, renal, lung, liver and prostate cancers. A phase II trial demonstrated efficacy in renal cancer with a 28 % objective response rate, stable ...
Tambuyzer Else - - 2013
This study assessed differences between service users', family carers' and mental healthcare providers' perceptions on service user and family carer involvement in mental healthcare. We conducted questionnaires in care networks for persons with serious and persistent mental illness, among 111 service users, 73 family carers and 216 mental healthcare providers. ...
Li Yan - - 2013
Some recent papers clearly indicate that the cytoplasmic domain of KcsA plays a role in pH sensing. We have performed, for the first time, a targeted molecular dynamics (TMD) simulation of the opening of full-length KcsA at pH 4 and pH 7, with a special interest for the cytoplasmic domain. ...
Roder Friedrich - - 2013
We have established an approach for the spatial control of lipid phase separation in tethered polymer-supported membranes (PSM), which were obtained by vesicle fusion on a PEG polymer brush functionalized with fatty acid moieties. Phase separation of ternary lipid mixtures (DOPC/SM/cholesterol) into liquid disordered (ld) and liquid ordered (lo) phases ...
McRae Jacqui Marie - - 2013
Different molecular structures of grape tannins have been shown to influence astringency, however the in-mouth sensory effects of different molecular structures in red wine tannins remains to be established. The objective of this research was to assess the impact of wine tannin structure on in-mouth sensory properties. Wine tannin was ...
Ninomiya Hironori - - 2013
ABSTRACT: BACKGROUND: A subset of lung adenocarcinomas harboring an EML4-ALK fusion gene resulting in dominant oncogenic activity has emerged as a target for specific therapy. EML4-ALK fusion confers a characteristic histology and is detected more frequently in never or light smokers and younger patients. METHODS: To gain insights into etiology ...
Vila-Costa Maria - - 2013
Bacteria and Archaea of the air-water surface microlayer (neuston) and plankton from three high mountain lakes (Limnological Observatory of the Pyrenees, Spain) were analyzed by 16S rRNA gene 454 pyrosequencing (V6 region) in two dates with different atmospheric aerosol loading conditions: (i) under a Saharan dust plume driven by southern ...
Kim In Sik - - 2013
(S)-(+)-decursin is a biological coumarin compound isolated from Angelica gigas Nakai. (S)-(+)-decursin and its analogue have a variety of pharmacological activities. In the present study, the anti-inflammatory effect of a (S)-(+)-decursin derivative, (S)-(+)-3-(3,4-dihydroxy-phenyl)-acrylic acid 2,2-dimethyl-8-oxo-3,4-dihydro-2H,8H-pyrano [3,2-g]-chromen-3-yl-ester (Compound 6, C6), on in vitro and in vivo atopic dermatitis was investigated. C6 ...
Ojeda-Uribe Mario - - 2013
The use of biological therapies for treating autoimmune diseases is increasing. These therapies are sometimes administered to pregnant women as part of a planned therapeutic regimen or to women with unexpected or unplanned pregnancies. The safety of biological therapies in this setting is a major issue. Here, we describe three ...
Chun Byung-Joon - - 2013
The objective of this study is to determine the efficacy of adding a prokinetic agent to proton pump inhibitors (PPI) for the treatment of laryngopharyngeal reflux (LPR) disease. A prospective, randomized open trial comparing lansoprazole plus itopride to lansoprazole single therapy was performed for 12 weeks. Sixty-four patients with a reflux ...
Fumagalli Romario Uberto - - 2013
BACKGROUND: Transabdominal preperitoneal (TAPP) repair is widely used to treat bilateral or recurrent inguinal hernias. Recently a self-gripping mesh has been introduced into clinical practice. This mesh does not need staple fixation and thus might reduce the incidence of chronic pain. This prospective study aimed to compare two groups of ...
Kalra Sanjay - - 2013
Abstract Background: Individual sulfonylurea agents differ in pharmacokinetic properties and clinical effects. This study aimed to describe the usage pattern, glycemic improvement, hypoglycemia, and change in body mass index (BMI) observed with commonly used sulfonylureas. Subjects and Methods: Patients of either gender with type 2 diabetes mellitus (T2DM), between 18 ...
Zhao Gaiping - - 2013
The present work formulates and analyzes the inhibitory effect of anti-angiogenic factor angiostatin excreted by the primary tumor on metastatic tumor angiogenesis, blood perfusion, and interstitial fluid flow in the tumor microenvironment by means of a numerical experiment. The simulation results demonstrate that angiostatin has an obvious impact on the ...
Anitua Eduardo - - 2013
Background: Regeneration of periodontal tissues is one of the most important goals for the treatment of periodontal disease. The technology of plasma rich in growth factors provides a biological approach for the stimulation and acceleration of tissue healing. The purpose of this study was to evaluate the biological effects of ...
Souza Marcy J - - 2013
Approximately 5.4 million cubic yards of coal fly ash and water spilled into the Emory River embayment of Watts Bar Reservoir in east Tennessee on Dec 22, 2008. Raccoons were collected in 2009 and 2010 from the spill site (10/y) and unexposed areas (5/y) to determine whether metals and metalloids ...
Lien Huang-Chun - - 2013
Phyllodes tumors (PTs) are characterized by co-proliferation of the stroma and epithelium, with the stroma being the neoplastic element. Ubiquitin carboxy-terminal hydrolase L1 (UCHL1) is a deubiquitinating enzyme that was originally considered to be a neuronal-specific marker, but later reports have shown both tumorigenic and antitumorigenic roles for UCHL1. Although ...
Chen Yue Long - - 2013
A naringinase from Aspergillus aculeatus JMUdb058 was purified, identified and characterized. This naringinase had a molecular mass (MW) of 348 kDa and contained four subunits with MWs of 100 kDa, 95 kDa, 84 kDa and 69 kDa. Mass spectrometric analysis revealed that the three larger subunits were β-D-glucosidases and that ...
Masumori K - - 2013
BACKGROUND: The aim of the present study was to classify the short-term outcomes of local correction of stoma prolapse with a stapler device. METHODS: The medical records of 11 patients undergoing local correction of stoma prolapse using a stapler device were retrospectively reviewed. RESULTS: No mortality or morbidity was observed ...
Weir Brad - - 2013
We introduce an implicit method for state and parameter estimation and apply it to a stochastic ecological model. The method uses an ensemble of particles to approximate the distribution of model solutions and parameters conditioned on noisy observations of the state. For each particle, it first determines likely values based ...
Kreeftmeijer-Vegter Annemarie Rosan - - 2013
Objective: To develop an oral solid dosage form of levamisole suitable for the paediatric population in terms of dose accuracy, palatability, stability and ease of administration. Methods: Small undividable tablets (Ø5 - 8 mm) in four different strengths were manufactured to allow for flexible and accurate dosing. In vitro dissolution ...
Han Lianhuan - - 2013
Substrate leveling is an essential but neglected instrumental technique of scanning electrochemical microscopy (SECM). In this technical note, we provide an effective substrate leveling method based on the current feedback mode of SECM. By using an air-bearing rotary stage as the supporter of electrolytic cell, the current feedback presents a ...
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