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Woo Sang Myung - - 2013
BACKGROUND: Few clinical studies to date have compared different types of self-expandable metallic stents (SEMS) and their outcomes in patients with pure duodenal obstruction caused by pancreaticobiliary cancer. The aim of this study was to compare the clinical effectiveness and side effects of uncovered and covered SEMS for the palliation ...
Lee Joo-Young - - 2013
Corynebacterium glutamicum was adapted in a chemostat for 1,900 h with gradually increasing H(2)O(2) stress to understand the oxidative stress response of an industrial host. After 411 generations of adaptation, C. glutamicum developed the ability to grow under stress of 10 mM H(2)O(2), whereas the wild-type did not. The adapted strain also ...
Mellor James D - - 2013
ABSTRACT: Antibody-dependent cellular cytotoxicity (ADCC) is a major mechanism of action of therapeutic monoclonal antibodies (mAbs) such as cetuximab, rituximab and trastuzumab. Fc gamma receptors (FcgR) on human white blood cells are an integral part of the ADCC pathway. Differential response to therapeutic mAbs has been reported to correlate with ...
Heng Eng Chee - - 2013
PURPOSE: Tocotrienol possess beneficial effects not exhibited by tocopherol. In vitro studies using animal models have suggested that these effects are caused via modulation of gene and protein expression. However, human supplementation studies using tocotrienol-rich isomers are limited. This study aims to identify plasma proteins that changed in expression following ...
Kanagasabai Parimala Suganthini - - 2013
OBJECTIVE: To investigate the effect of Auditory, Tactile, Visual and Vestibular stimulus (ATVV) on neuromotor development in preterm infants. METHODS: Fifty preterm infants born at 28-36 wk with a birth weight ranging from 1,000-2,000 g were recruited for the study. They were block randomized into a control group (n = 25) and study group ...
Tumilty Les - - 2013
Acute tyrosine administration is associated with increased exercise capacity in the heat. To explore whether reduced plasma tyrosine and phenylalanine (tyrosine precursor) is associated with impaired exercise capacity in the heat, eight healthy, moderately trained male volunteers, unacclimated to exercise in the heat, performed two tests in a crossover design ...
Mihai Gazdag Emerich E Max-Planck-Institute of Molecular Physiology, Department of Physical Biochemistry, Dortmund 44227, - - 2013
Legionella pneumophila is an intracellularly surviving pathogen that releases about 270 different proteins into the host cell during infection. A set of secreted proteins takes control of the vesicular trafficking regulator Rab1. Legionella LepB inactivates Rab1 by acting as a GTPase-activating protein (GAP). We present the crystal structure of the ...
Zhang Xiaoli - - 2013
PURPOSE: The aim of the study was to determine whether glucose uptake in viable myocardium of ischemic cardiomyopathy patients depends on rest myocardial blood flow (MBF) and the residual myocardial flow reserve (MFR). METHODS: Thirty-six patients with ischemic cardiomyopathy (left ventricular ejection fraction 25 ± 10 %) were studied with (13)N-ammonia and (18)F-fluorodeoxyglucose ...
Qiu Xiaoqing - - 2013
A direct and scalable approach for the synthesis of iron sulfide (FeS(2)) films on flexible iron (Fe) foil in aqueous solution has been developed.
Wang Lianggui - - 2013
This research involved the use of response surface methodology (RSM) to investigate the adsorption of Disperse Red 167 dye onto the bamboo-based activated carbon activated with H(3)PO(4) (PBAC) in a batch process. F400, a commercially available activated carbon, was used in parallel for comparison. Analysis of variance showed that input ...
Bryś Magdalena - - 2013
The biological behavior of prostate cancer is uncertain, and therefore, search for molecular prognostic markers associated with disease progression seems to be essential. We performed microsatellite allelotyping of DNA isolated from primary prostate tumors biopsies (prostate adenocarcinoma, PCa). We evaluated the frequency of allelic imbalance (AI), including loss of heterozygosity ...
Marradi Marco - - 2013
The quest for the construction of multivalent carbohydrate systems, with precise geometries that are highly efficient in interacting with carbohydrate binding proteins, has been a goal of synthetic chemists since the discovery of the multivalent nature of carbohydrate-mediated interactions. However, the control of the spatial and topological requirements for these ...
Schulz Christian - - 2013
ABSTRACT: BACKGROUND: By 2013 Palliative Care will become a mandatory examination subject in the medical curriculum in Germany. There is a pressing need for effective and well-designed curricula and assessment methods. Debates are on going as how Undergraduate Palliative Care Education (UPCE) should be taught and how knowledge and skills ...
Pawani Harsha - - 2013
Human embryonic stem cells (hESCs) have the ability to differentiate into all the three lineages and are an ideal starting material to obtain cells of desired lineage for regenerative medicine. Continued efforts are needed to evolve more robust protocols to obtain cells of desired lineages and in larger numbers. Also, ...
Guo Xiaola - - 2013
Control of organ size by cell expansion and cell proliferation is a fundamental process during development, but the importance of BIG in this process is still poorly understood. Here, we report the isolation and characterization of a new allele mutant of BIG in Arabidopsis: big-j588. The mutant displayed small aerial ...
Olsson E Gunilla A EG School of Global Studies, Global Sustainability Studies, Human Ecology, University of Gothenburg, Box 700, 405 30, Gothenburg, Sweden. - - 2013
The REDD+ scheme of the United Nations intends to offer developing countries financial incentives to reduce the rates of deforestation and forest degradation for reducing global CO2 emissions. This is combined with building carbon stocks in existing wooded ecosystems and fostering other soil, biodiversity and water conservation objectives. Successful application ...
Xu Junjie - - 2013
ABSTRACT: BACKGROUND: Yunnan has the largest number of reported HIV/AIDS cases among all Chinese provinces, the reported prevalence of HIV among Yunnan men who have sex with men (MSM) passed 10%, while HIV incidence epidemic and molecular characteristics of new infected Yunnan MSM were not evaluated before. METHODS: An 18 ...
Sagarzazu Gabriel - - 2013
Time-resolved photoluminescence (PL) and transient absorption (TA) spectroscopy are conducted in order to get knowledge on the excited state of CdSe nanorods (NR), and to assess the impact of Au nanoparticles (NP) on the carrier dynamics of hybrid Au-CdSe NRs. The decay dynamics measured in solution show an increase of ...
Sainsbury Peter Geoffrey - - 2013
The prevalence of chronic diseases has increased in recent decades. Some forms of the built environment adopted during the 20th century-e.g., urban sprawl, car dependency, and dysfunctional streetscapes-have contributed to this. In this article, I summarise ways in which the built environment influences health and how it can be constructed ...
Kong Feng - - 2013
Past studies have suggested important links between valence and perception and action in physical space. The present study aimed to test the associations between emotional valance for words or faces and manual responses in left- and right-handers. We employed a divided output (bimanual) reaction time paradigm in which participants had ...
Karacı S - - 2013
Reduction mammaplasty is one of the most frequently performed operations in plastic surgery. Breast scarring can be troublesome for both the patient and the surgeon. This report offers an easy method for suturing a vertical incision that provides a better shape in final breast appearance. In this study, 10 patients ...
Pearson James - - 2013
Dehydration and hyperthermia reduces leg blood flow (LBF), cardiac output ([Formula: see text]) and arterial pressure during whole-body exercise. It is unknown whether the reductions in blood flow are associated with dehydration-induced alterations in arterial blood oxygen content (C (a)O(2)) and O(2)-dependent signalling. This study investigated the impact of dehydration ...
Thomas Vernon George VG Department of Integrative Biology, College of Biological Science, University of Guelph, Guelph, ON, N1G 2W1, Canada, - - 2013
Proposals to end the use of lead hunting ammunition because of the established risks of lead exposure to wildlife and humans are impeded by concerns about the availability, price, and effectiveness of substitutes. The product availability and retail prices of different calibers of lead-free bullets and center-fire rifle ammunition were ...
Yamada Akimitsu A Department of Clinical Oncology and Breast Surgery, Yokohama City University, 3-9 Fukuura, Kanazawa-ku, Yokohama, Kanagawa, - - 2013
ATP-binding cassette (ABC) transporters are membrane proteins that efflux various compounds from cells, including chemotherapeutic agents, and are known to affect multidrug resistance. Recent reports disagree on whether ABCC11 is a risk factor for breast tumorigenesis, but its expression in breast cancer is poorly investigated. We hypothesized that both frequency ...
Bhutani Divaya - - 2013
Over the last decade, the field of oncology has undergone revolutionary changes. One of the major reasons contributing to this change is the improvement in our understanding of the biology of cancer. Recognition of novel targets on the cancer cell has enabled development of tools to attack those targets. Monoclonal ...
Xavier Rui - - 2013
The delivery approach, though very appropriate for remodeling the tip of the nose, has been overlooked in recent years and has often been passed over for the open approach. One reason for this is the intercartilaginous incision used for the delivery approach, which may cause scarring at the nasal valve ...
Popp Lothar - - 2013
PURPOSE: Combined rectal and vaginal prolapse requires a complete repair of the pelvic floor that can only be achieved by an interdisciplinary management. We have, therefore, established a co-operation for preoperative diagnosis, interdisciplinary operations, and postoperative care involving a colorectal surgeon and a gynecologist. METHODS: Our standardized operation, which we ...
Cadore E L EL Exercise Research Laboratory, Physical Education School, Federal University of Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, - - 2013
The purpose of the present study was to review the scientific literature that investigated concurrent training adaptations in elderly populations, with the aim of identifying the optimal combination of both training program variables (i.e., strength and endurance) to avoid or minimize the interference effect in the elderly. Scielo, Science Citation ...
Amato G - - 2013
BACKGROUND: The study is focused on recognizing the histological changes of the structures close to and around the hernia opening in patients having direct inguinal hernia. METHODS: In 15 patients with primary bilateral direct inguinal hernia who underwent a Stoppa open posterior inguinal hernia repair, tissue specimens from the abdominal ...
Bel-Serrat Silvia - - 2013
OBJECTIVE: To compare, specifically by age group, proxy-reported food group estimates obtained from the food frequency section of the Children's Eating Habits questionnaire (CEHQ-FFQ) against the estimates of two non-consecutive 24 h dietary recalls (24-HDR). DESIGN: Estimates of food group intakes assessed via the forty-three-food-group CEHQ-FFQ were compared with those ...
Orski Sara V - - 2013
A two-dimensional model of a solid-supported enzyme catalyst bead is fabricated on a quartz crystal microbalance with dissipation monitoring (QCM-D) sensor to measure in situ interfacial stability and mechanical properties of Candida antarctica Lipase B (CAL B) under varied conditions relating to ring-opening polymerization. The model was fabricated using a ...
Ko Shun-Yao - - 2013
Diabetic cardiomyopathy has been shown to promote hypertrophy, leading to heart failure. Recent studies have reported a correlation between diabetic cardiomyopathy and oxidative stress, suggesting that the accumulation of advanced glycation end products (AGEs) induces the production of reactive oxygen species (ROS). In a clinical setting, AGEs have been shown ...
Rouzi Abdulrahim A - - 2013
Female genital mutilation (FGM) is a very ancient traditional and cultural ritual. Strategies and policies have been implemented to abandon this practice. However, despite commendable work, it is still prevalent, mainly in Muslim countries. FGM predates Islam. It is not mentioned in the Qur'an (the verbatim word of God in ...
Eitam Baruch - - 2013
Human motivation is sensitive to value-to the outcomes of actions. People invest mental and physical resources for obtaining desired results or for stopping and reversing undesired ones. Accordingly, people's motivation is sensitive to information about their standing in relation to outcome attainment ('outcome feedback'). In this paper, we argue and ...
Ma Dik-Lung - - 2013
Approved drugs have favourable or validated pharmacokinetic properties and toxicological profiles, and the repositioning of existing drugs for new indications can potentially avoid expensive costs associated with early-stage testing of the hit compounds. In recent years, technological advances in virtual screening methodologies have allowed medicinal chemists to rapidly screen drug ...
Allen Jeffrey A - - 2013
Gastrostomy tube placement for malnutrition and weight loss stabilization occurs in many patients with ALS. We sought to compare the outcome and complications of gastrostomy tube placement by endoscopic (PEG) and multiple radiologic (RIG) methods in ALS patients. A retrospective analysis was conducted on all ALS patients evaluated at Northwestern ...
Meeney A A National Specialist Ophthalmic Pathology Service (NSOPS), Department of Histopathology, Royal Hallamshire Hospital, Sheffield, UK. - - 2013
The advanced specialist diploma in ophthalmic pathology was jointly ratified by the Royal College of Pathologists and the Institute of Biomedical Science in 2008. It results in extended roles for suitably qualified Biomedical Scientists (BMSs) in ophthalmic pathology specimen dissection and histological reporting of selected specimens, specifically non-neoplastic corneas. This ...
Murphy Siun - - 2013
The recent observation of anaplastic large cell lymphoma (ALCL) in association with breast implants has initiated a large amount of literature recently, particularly in light of the issues with Poly Implant Prosthese implants. There are now approximately 35-50 reports of this lymphoma associated with breast implants. One of the presenting ...
Saberi Hosnijeh Fatemeh F Division Environmental Epidemiology, Institute for Risk Assessment Sciences, Utrecht University, Jenalaan 18D, PO Box 80178, 3508 TD Utrecht, Netherlands. - - 2013
Overweight and obesity have been suggested as a risk factor for leukemia. Impaired immune function associated with obesity, increased insulin-like growth factor-I activity and stimulating effects of leptin suggest a possible biological link between anthropometric measures and leukemia. However, evidence from epidemiological studies has been inconsistent. We examined the potential ...
Carta Mario M Université Bordeaux, Institut Interdisciplinaire de Neurosciences, UMR 5297, Bordeaux, - - 2013
Calmodulin-dependent kinase II (CaMKII) is key for long-term potentiation of synaptic AMPA receptors. Whether CaMKII is involved in activity-dependent plasticity of other ionotropic glutamate receptors is unknown. We show that repeated pairing of pre- and postsynaptic stimulation at hippocampal mossy fibre synapses induces long-term depression of kainate receptor (KAR)-mediated responses, ...
Ferrer Gerardo - - 2013
ABSTRACT Chronic lymphocytic leukemia (CLL) is frequently associated with autoimmune hemolytic anemia (AIHA). However, the mechanisms governing the association between CLL and AIHA are poorly understood. miRNAS have been associated with different clinico-biological forms of CLL and are also known to play a substantial role in autoimmunity. However, there are ...
Wakamoto Yuichi - - 2013
Exposure of an isogenic bacterial population to a cidal antibiotic typically fails to eliminate a small fraction of refractory cells. Historically, fractional killing has been attributed to infrequently dividing or nondividing "persisters." Using microfluidic cultures and time-lapse microscopy, we found that Mycobacterium smegmatis persists by dividing in the presence of ...
Rottler Ann-Marie - - 2013
The signalling functions of cuticular lipids, particularly cuticular hydrocarbons, have gained considerable attention in social insect communication. Information transfer between individuals by means of these substances has been examined extensively. However, communication with cuticular lipids is not limited to inter-individual recognition. Cuticular compounds can also have a signalling function in ...
Kalina Ondrej - - 2013
Background and objectives There is strong evidence that parental processes such as monitoring and social support play an important role with regard to sexual risk behaviour among adolescents. We wished to explore the influence of both parents' monitoring and support on sexual risk behaviour among adolescent boys and girls. Methods ...
Fitzgerald Desmond J DJ UCD Conway Institute and Java Clinical Research, University College Dublin, - - 2013
The development of drugs that inhibit platelets has been driven by a combination of clinical insights, fundamental science, and sheer luck. The process has evolved as the days of stumbling on therapeutic gems, such as aspirin, have long passed and have been replaced by an arduous process in which a ...
O'Leary Timothy P - - 2013
We examined measures of locomotor and anxiety-like behavior in male and female mice of 15 inbred strains on the elevated-plus maze, light/dark transition box and open field. Strain differences were found on all measures of locomotor activity and anxiety. Strain means for measures of locomotor activity on the three apparatus ...
Rivera Itza - - 2013
The purpose of this study was to compare pain frequency in early and late stages of ALS and to describe the relationship between pain intensity and functional status. Sixty-four patients in different stages of ALS were asked to complete the Neuropathic Pain Scale and to draw the localization of their ...
Kang N H NH Department of Ophthalmology, Ewha Womans University, Seoul, Republic of - - 2013
To assess the change in subfoveal choroidal thickness (SFCT) in central serous chorioretinopathy (CSC) following spontaneous resolution and low-fluence photodynamic therapy (PDT) using the enhanced depth imaging optical coherence tomography (EDI-OCT). A total of 36 consecutive eyes of 36 patients were included in this retrospective study: 16 eyes with spontaneously ...
Czirják Gábor Arpád - - 2013
The preen gland is a holocrine sebaceous gland of the avian integument which produces an oily secretion that is spread on the plumage during preening. It has been suggested that birds may defend themselves against feather-degrading bacteria (FDB) and other potential pathogens using preen gland secretions. However, besides some in ...
Sedgwick Garry G GG The Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Copenhagen, - - 2013
The Anaphase Promoting Complex/Cyclosome (APC/C) in complex with its co-activator Cdc20 is responsible for targeting proteins for ubiquitin-mediated degradation during mitosis. The activity of APC/C-Cdc20 is inhibited during prometaphase by the Spindle Assembly Checkpoint (SAC) yet certain substrates escape this inhibition. Nek2A degradation during prometaphase depends on direct binding of ...
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