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Alvarado-Esquivel C - - 2013
The epidemiology of toxocariasis in humans in Mexico has been poorly explored. There is a lack of information about toxocariasis in Tepehuanos, an indigenous ethnic group in Durango State in northern Mexico. Therefore, the presence of anti-Toxocara immunoglobulin (Ig) G antibodies was determined in 126 rural Tepehuanos using an enzyme-linked ...
Degarege A - - 2013
In this cross-sectional study, the associations between helminth infections and ABO blood group, anaemia and undernutrition were investigated in 480 febrile outpatients who visited Dore Bafeno Health Centre, southern Ethiopia, in December 2010. Stool specimens were processed using the Kato-Katz method and examined for intestinal helminth infections. Haemoglobin level was ...
Lin Jie - - 2013
PURPOSE: We describe the preclinical pharmacology and anti-tumor activity of GDC-0068, a novel highly selective ATP-competitive pan-Akt inhibitor currently in clinical trials for the treatment of human cancers. EXPERIMENTAL DESIGN: The effect of GDC-0068 on Akt signaling was characterized using specific biomarkers of the Akt pathway, and response to GDC-0068 ...
Fisher Jeffrey W - - 2013
A biologically-based dose response (BBDR) model for the hypothalamic-pituitary thyroid (HPT) axis in the lactating rat and nursing pup was developed to describe the perturbations caused by iodide deficiency on the HPT axis. Model calibrations, carried out by adjusting key model parameters, were used as a technique to evaluate HPT ...
Calì Giuseppe - - 2013
Objective: Evaluate the diagnostic accuracy of 2D gray-scale, Colour Doppler and 3D power Doppler sonographic criteria for morbidly adherent placenta, and identify criteria to help distinguish placenta accreta from percreta. Methods: 187 patients with placenta previa and history of uterine surgery were enrolled in our study and performed a transabdominal ...
Symes Mark D - - 2013
A dyad complex has been constructed as a soluble molecular model of a heterogeneous cobalt-based oxygen-evolving catalyst (Co-OEC). To this end, the Co(4) O(4) core of a cobalt-oxo cubane was covalently appended to Re(I) photosensitisers. The resulting adduct was characterised both in the solid state (by X-ray diffraction) and in ...
Homeyer Nadine - - 2013
In the later stages of drug design projects, accurately predicting relative binding affinities of chemically similar compounds to a biomolecular target is of utmost importance for making decisions based on the ranking of such compounds. So far, the extensive application of binding free energy approaches has been hampered by the ...
Thimm Dominik - - 2013
Adenosine A(2B) receptors, which play a role in inflammation and cancer, are of considerable interest as novel drug targets. To gain deeper insights into ligand binding and receptor activation we exchanged amino acids predicted to be close to the binding pocket. The alanine mutants were stably expressed in CHO cells ...
Bisschop Peter H - - 2013
The hypothalamus is a major target for glucocorticoids and key structure for hypothalamus-pituitary-adrenal (HPA) axis setpoint regulation. The enzyme 11beta hydroxysteroid dehydrogenase type 1 (11βHSD1) modulates glucocorticoid signalling in various tissues at the prereceptor level by converting biologically inactive cortisone to its active form cortisol. The objective of our study ...
Li Zheling - - 2013
Raman spectroscopy has been used for the first time to monitor interfacial stress transfer in poly(vinyl alcohol) nanocomposites reinforced with graphene oxide (GO). The graphene oxide nanocomposites were prepared by a simple mixing method and casting from aqueous solution. They were characterized using scanning electron microscopy, X-ray diffraction, and polarized ...
Ye Baihua - - 2013
The lack of robust and tunable chiral versions of cyclopentadienyl (Cp) ligands hampers progress in the development of catalytic asymmetric version of a myriad of reactions catalyzed by this ubiquitous ligand. Herein, we describe of a class of chiral Cp ligands with tunable steric parameters. Coordinated to transition metals, the ...
Yin Li-Jung - - 2013
An acid protease from the broth of a 24-hour cultivated Aspergillus niger BCRC 32720 was purified to electrophoretical homogeneity by CM Sepharose FF and Sephacryl S-100 HR chromatographs. The specific activity, purification fold and yield were 23.29 kU/mg, 2.5 and 24.2%, respectively. Molecular mass (M) and N-terminal amino acid sequence ...
Chang Yao-Lung - - 2013
SUBJECT: This study investigates the placental autophagic activity in growth-restricted fetuses in the monochorionic (MC) twin model. PATIENTS AND METHODS: Forty MC twins were prospectively enrolled in this study, including 21 with and 19 without selective intrauterine growth restriction (sIUGR), defined as birth weight below the tenth percentile. The sIUGR ...
Ghi Tullio - - 2013
Objectives: To compare the longitudinal changes of the angle of progression (AoP) and the midline angle (MLA) during the active second stage according to the mode of delivery. Methods: A three-dimensional translabial ultrasound volume was acquired in a series of nulliparous women at the beginning of the active second stage ...
Dayer M J - - 2013
BACKGROUND: Since the introduction of the National Institute for Health and Clinical Excellence (NICE) guideline (CG064) in 2008 recommending cessation of antibiotic prophylaxis (AP) against infective endocarditis (IE), low level prescribing persists in the UK and is a potential reason why there has been no significant change in the general ...
Hajdu Steven I - - 2013
In the 3 decades from 1910 to 1940, more progress took place in cancer research and the diagnosis and treatment of cancers than during the prior centuries combined. The discovery of several carcinogens, precancerous conditions, and hereditary cancers adduced new thoughts about the genesis of cancers. Even though diagnostic radiology ...
Gupta Sanjay - - 2013
The study was undertaken to assess the utility of cervico-vaginal/vault cytology in the follow-up of women treated for cervical cancer and benign gynecological conditions. Records of 3,523 cervico-vaginal smears from 2,658 women who underwent hysterectomy and/or radiotherapy or chemotherapy, over a 10-year period were retrieved. Data was collected on type ...
Sahu Kalyanasis - - 2013
Measurements of biexciton decays in semiconductor nanoparticles are easily contaminated by contributions from photoproducts or higher excitons. Theoretical work has shown that multiple population-period transient spectroscopy (MUPPETS) can measure biexciton decays free from these interferences. In this communication, the biexciton decay of CdSe/ZnS core-shell nanoparticles is measured with MUPPETS. The ...
Jónsdóttir Thórunn - - 2013
Objective. To investigate the long-term clinical, histological and serological affects of B-cell-depleting therapy (BCDT) in patients with LN refractory to conventional treatment.Methods. Twenty-five patients, followed for a mean time of 36 months (9-95 months), were included. Renal disease activity was evaluated with the BILAG index and renal response was determined ...
Chen Ming-Chung - - 2013
The aim of this study was to investigate the effect of gold nanoparticle (Au NP)-induced surface plasmons on the performance of organic photovoltaics (OPVs) that consist of copper phthalocyanine and fullerene as the active materials. The photon absorption can be enhanced by immobilization of surfactant-stabilized Au NPs on a self-assembled ...
Macklai Nejma S - - 2013
ABSTRACT: BACKGROUND: Among the many definitions of frailty, the frailty phenotype defined by Fried et al. is one of few constructs that has been repeatedly validated: first in the Cardiovascular Health Study (CHS) and subsequently in other large cohorts in the North America. In Europe, the Survey of Health, Aging ...
Vanherberghen Bruno - - 2013
Despite intense scrutiny of the molecular interactions between natural killer (NK) and target cells, few studies have been devoted to dissection of basic functional heterogeneity in individual NK cell behavior. By using a microchip-based, time-lapse imaging approach allowing the entire contact history of each NK cell to be recorded, we ...
Thornton Paul D - - 2013
The generation of a range of star-shaped block copolymers composed of a biocompatible poly(ethylene glycol) (PEG) core tethered to a polyalanine (PAla) shell that possesses the capability to (reversibly) self-assemble in water is described. The hydrogels formed offer a hydrophilic environment ideal for biological processes involving proteins and are able ...
Annett R W - - 2013
A study was undertaken to investigate the performance of breeding ewes fed a range of forage and concentrate-based diets in late pregnancy, balanced for supply of metabolizable protein (MP). For the final 6 weeks before lambing, 104 twin-bearing multiparous ewes were offered one of four diets: ad libitum precision-chop grass ...
Johnsen Lærke - - 2013
Mounting evidence led us to hypothesize that: 1) function of the thyroid hormone (TH) axis can be programmed by late-gestation undernutrition (LG-UN), and 2) early-postnatal-life overnutrition (EL-ON) exacerbates the fetal impacts on TH-axis function. In a 2×2 factorial experiment, 21 twin-bearing sheep were fed one of two diets during late ...
Massollo Michela - - 2013
In the course of metformin treatment, staging abdominal cancer lesions with (18)F-FDG PET images is often hindered by the presence of a high bowel radioactivity. The present study aimed to verify the mechanism underlying this phenomenon. METHODS: Fifty-three mice were submitted to dynamic acquisitions of (18)F-FDG kinetics under fasting conditions. ...
Boskovic Jelena - - 2013
Aims: The aims of this study was to determine adherence to chronic disease medication measured by self-reported questionnaire. Methods: The survey was conducted at 106 Zagreb pharmacies, and the questionnaire was filled out by the study subjects. Results: A total 1,357 diagnoses were reported by survey respondents (i.e., an average ...
Streit Jason K - - 2013
A new method is described for measuring the short-wave infrared (SWIR) emission wavelengths of numerous individual nanoparticles without using a dedicated spectrometer. Microscope objectives designed for use at visible wavelengths often show severe axial chromatic aberration in the SWIR. This makes coplanar objects emitting at different SWIR wavelengths appear to ...
Ahmed Imad Am - - 2013
The harsh chemical conditions involved in the isolation of fulvic acids (FA) and humic acids (HA) have been identified as a possible contributing factor to the significant mismatch between in situ measurements and model predictions of trace metal speciation in freshwaters, resulting from the use of isolated FA and HA ...
Simpson Vickie S - - 2013
ABSTRACT BACKGROUND Adult studies have demonstrated that ventilator-associated tracheobronchitis (VAT) may be a precursor to ventilator-associated pneumonia. No published data on VAT in pediatric intensive care units (PICU) were found. The purpose of this retrospective, descriptive study is to describe the incidence, characteristics and outcomes of patients at risk for ...
Andreychuk Nicholas R - - 2013
A NON-issue: Potassium complexes of an extremely rigid and sterically encumbered NON-donor ligand have been prepared, and the solid-state structures feature remarkably short potassium-alkane distances. DFT calculations highlight the presence of an electrostatic cation-induced dipole potassium-alkane interaction supported by interactions between the alkane and the surrounding ligand framework.
Kempa M - - 2013
The position and size of the energy gap in the phonon density of states of NaI single crystal have been investigated by inelastic neutron scattering in a wide range of temperatures from 10 to 700 K. The results reveal a pronounced temperature effect which effectively leads to closure of the phonon ...
Park S H - - 2013
INTRODUCTION: The CellaVision DM96 system (CellaVision AB, Lund, Sweden) was developed as one of the automated digital cell morphology analyzer for determining leukocyte differential counts in peripheral blood smears (PBS) and we evaluated this system. METHODS: A total of 308 PB samples with abnormalities were analyzed in this study. For ...
Drenner Ray W - - 2013
Mercury (Hg) is a toxic metal that is found in aquatic food webs and is hazardous to human and wildlife health. We examined the relationship between Hg deposition, land coverage by coniferous and deciduous forests and average Hg concentrations in largemouth bass (Micropterus salmoides) equivalent fish (LMBE) in 14 ecoregions ...
Hao Zhenhua - - 2013
Thermoresponsive synergistic hydrogen bonding (H-bonding) switched by several guest units in a water-soluble polymer is reported. Adjusting the distribution of guest units can effectively change the synergistic H-bonding inside polymer chains, thus widely switch the preorganization and thermoresponsive behavior of a water-soluble polymer. The synergistic H-bonding is also evidenced by ...
Yuan Hong - - 2013
Ovarian cancer is a highly invasive and metastatic disease with a poor prognosis if diagnosed at an advanced stage, which is often the case. Recent studies argue that ovarian cancer cells that have undergone epithelial to mesenchymal transition (EMT) acquire aggressive malignant properties, but the relevant molecular mechanisms in this ...
Ma Xiao-Song - - 2013
The counterintuitive features of quantum physics challenge many common-sense assumptions. In an interferometric quantum eraser experiment, one can actively choose whether or not to erase which-path information (a particle feature) of one quantum system and thus observe its wave feature via interference or not by performing a suitable measurement on ...
Coadou Erwan - - 2013
Herein, we present a comparative study of thermophysical properties of two homologous ionic liquids, namely trimethyl-sulfonium bis[(trifluoromethyl)sulfonyl]imide, [S111][TFSI], and trimethyl-ammonium bis[(trifluoromethyl)sulfonyl]imide, [HN111][TFSI], and their mixtures with propylene carbonate, acetonitrile or gamma butyrolactone as a function of temperature and composition. The influence of solvent addition on the viscosity, conductivity and thermal ...
Wang Meiyao - - 2013
CD4 (cluster of differentiation 4) is an important glycoprotein containing a transmembrane portion and a short intracellular tail. It locates on the surface of various types of immune cells and performs a critical role in multiple cellular functions such as signal amplification and activation of T cells. It is well ...
Chimienti Fabrice - - 2013
Zn is an essential trace element, involved in many different cellular processes. A relationship between Zn, pancreatic function and diabetes was suggested almost 70 years ago. To emphasise the importance of Zn in biology, the history of Zn research in the field of diabetes along with a general description of ...
Majumdar Arka - - 2013
Efficient conversion of electrical signal to optical signal in nano-photonics enables solid state integration of electronics and photonics. Combination of graphene with photonic crystals is promising for electro-optic modulation. In this paper, we demonstrate that by electrostatic gating a single layer of graphene on top of a photonic crystal cavity, ...
Park Young Min - - 2013
OBJECTIVES/HYPOTHESIS: The objective of this prospective study was to confirm the validity of transoral robotic supraglottic partial laryngectomy as a conservation surgery for treating supraglottic cancer. STUDY DESIGN: Prospective case study. METHODS: Between December 2009 and November 2011, 16 patients were enrolled in this study. Acoustic waveform analysis was conducted ...
Cirriez Virginie - - 2013
How to train your silane: A new family of chiral copper(I) complexes that bear a bifluoride counteranion were prepared and used in the first example of the enantioselective transfer of a silyl group to an aldehyde. This procedure provides fast access to non-racemic α-hydroxysilanes in high enantioselectivities.
Patel Dhavalkumar - - 2013
OBJECTIVE: To prospectively evaluate whether the development of fibroatheromas exhibiting features of potential instability can be detected and predicted by serial invasive imaging. METHODS AND RESULTS: Multivessel intravascular ultrasound and near infrared spectroscopy (NIRS) were performed in diabetic/hypercholesterolemic pigs 3, 6, and 9 months after induction. Animals were euthanized at ...
Reitzel Lorraine R - - 2013
INTRODUCTION: The Food and Drug Administration is in the process of reviewing evidence of the impact of mentholated cigarettes on smoking behaviors and smoking cessation in order to determine if these products should be removed from the market. More empirical research is needed to inform those decisions. The goal of ...
Niu Yuge - - 2013
The effects of sulfation, hydroxypropylation and succinylation on gelling, water uptake, swelling, and bile acid-binding capacities of psyllium were examined and compared on a same molar substitution degree. Sulfated, hydroxypropyl and succinyl psyllium were prepared with a substitution level of 1.02, 0.88 and 0.79, respectively, and their structures were characterized ...
Li Bin - - 2013
Herein, we develop a reproducible in-situ crystallization route to synthesize uniform functional ZSM-5 microspheres composed of aggregated-ZSM-5 nanorods and well-dispersed uniform Fe3O4 nanoparticles. The growth of such unique microspheres undergoes a nanoparticle-assisted recrystallization process from surface to core. The obtained magnetic ZSM-5 microspheres possess a uniform size (6 - 9 ...
Dominissini Dan - - 2013
N(6)-methyladenosine-sequencing (m(6)A-seq) is an immunocapturing approach for the unbiased transcriptome-wide localization of m(6)A in high resolution. To our knowledge, this is the first protocol to allow a global view of this ubiquitous RNA modification, and it is based on antibody-mediated enrichment of methylated RNA fragments followed by massively parallel sequencing. ...
Agee Carl B - - 2013
We report data on the martian meteorite, Northwest Africa (NWA) 7034, which shares some petrologic and geochemical characteristics with known martian (SNC, i.e., Shergottite, Nakhlite, and Chassignite) meteorites, but also possesses some unique characteristics that would exclude it from the current SNC grouping. NWA 7034 is a geochemically enriched crustal ...
Ma Jun - - 2013
We report measurements and modeling of thermal conductivity in periodic three-dimensional dielectric nanostructures: silicon inverse opals. Such structures represent a three-dimensional "phononic crystal" but affect heat flow instead of acoustics. Employing the Stober method, we fabricate high quality silica opal templates that on filling with amorphous silicon, etching and recrystallizing ...
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