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Lee Jae Sung - - 2013
The sensitivity of post-tetanic potentiation (PTP) to high frequency stimulation (HFS) steeply decays during the first two postnatal weeks. We investigated the underlying mechanisms for the developmental change of PTP induced by HFS (100 Hz, 2 sec) at postnatal days 4-6 and 9-11 at the rat calyx of Held synapse. ...
Zhang Yan - - 2013
INTRODUCTION: This study was performed to address the pathological roles of the skeletal renin-angiotensin system (RAS) in type 1 diabetes-induced osteoporosis and the effects of the angiotensin II type 1 receptor blocker losartan on bones in diabetic mice. MATERIALS AND METHODS: Bone histomorphology was detected by H&E staining, Safranin O ...
Swindle M Michael - - 2013
ABSTRACT The authors have extensive experience in surgery, anesthesia, and perioperative care in both miniature and domestic swine in the research setting. This manuscript describes the techniques that have been developed over the last four decades while developing porcine surgical models and their use in translational research. Swine are conditioned ...
Teng Jing - - 2013
In complex materials, how correlation between charge, spin, and lattice affects the emergent phenomena remains unclear. The newly discovered iron-based high-temperature superconductors and related compounds present to the community a prototype family of materials, where interplay between charge, spin, and lattice degrees of freedom can be explored. With the occurrence ...
Ji Xiang - - 2013
In this work, an asymmetric swelling-dissolving process of original sub-micron sized decentered sulfonated polystyrene/silica (SPS/silica) particles in a ternary mixed solvent (water/ethanol/heptane) was first reported. Actinia-like and porous snowman-like SPS/silica composite particles are fabricated through tuning the composition of the ternary mixed solvent. Actinia-like particles, with a silica core embedded ...
Howard Luke R - - 2013
Chokeberry anthocyanins are susceptible to degradation during processing and storage of processed products. In this study we determined the effects of three pH levels (2.8, 3.2, and 3.6) and four beta cyclodextrin (BCD) concentrations (0, 0.5, 1, and 3%) alone and in combination on the stability of chokeberry juice anthocyanins ...
Jiang Liyun - - 2013
ABSTRACT: BACKGROUND: Dengue virus (DENV) infection is the most prevalent arthropod-borne viral infection in tropical and subtropical regions worldwide. Guangzhou has the ideal environment for DENV transmission and DENV epidemics have been reported in this region for more than 30 years. FINDINGS: In this study, the epidemiological and virological characteristics ...
Kliegman Sarah - - 2013
The phototransformation of triclosan has been a matter of longstanding interest due to both its prevalence in the environment and the discovery of 2,8 dichlorodibenzodioxin as a photoproduct. In this study, photolysis of triclosan resulted in several primary photoproducts including: 2,8-dichlorodibenzodioxin (4 %), 4,5'-dichloro-[1,1'-biphenyl]-2,2'-diol (10 %), 5-chloro-2-(4-chlorophenoxy)phenol (0.5 %), and ...
Peebles Charles - - 2013
The year of 2012 has seen many significant publications in cardiac imaging, particularly in the modalities of cardiovascular magnetic resonance and cardiac computed tomography. This article will review in brief some of the most important studies with a particular emphasis on the new evidence base for perfusion imaging both by ...
Frank Richard G - - 2013
There are 9.2 million people who are eligible for both Medicare and Medicaid. They're eligible for both programs either because they are younger than 65 years of age, disabled, and poor or because they are 65 or older and are poor or have exhausted their nonhousing assets paying for health ...
Coupaye Muriel - - 2013
Context:Children with Prader-Willi syndrome (PWS) who receive GH treatment have improved growth and body composition; however, data are lacking for adults when treatment is discontinued after completion of growth.Objectives:Our aim was to compare body composition and metabolic status in adults with PWS according to GH treatment in childhood and adolescence.Design:64 ...
Lee Won-Mo - - 2013
Purpose: To investigate the effects of rapamycin on the TNF-α-induced secretion of interleukin-6 (IL-6) and IL-8 in orbital fibroblasts and its possible mechanism. Materials and methods: Orbital fibroblasts were obtained from patients with thyroid-associated ophthalmopathy. IL-6 and IL-8 levels were measured by enzyme-linked immunosorbent assays. The down-regulation of PDCD4 was ...
Abedelmalek Salma - - 2013
The purpose of this study was to evaluate the effects of partial sleep deprivation (PSD) on circulating concentrations of interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-α) in relation to the secretory profiles of growth hormone (GH), cortisol, and testosterone during a repeated brief sprint interval exercise. Thirty healthy football players ...
Kaufman Yair - - 2013
Supported biomimetic membranes (SBM) on solid substrates have been commonly prepared from vesicle-forming double-tail lipids, such as zwitterionic phospholipids, using the method of vesicle fusion. Here we report on the preparation of SBMs on silica surfaces via a similar process of "micelle fusion" from a cationic single-tail bolaamphiphile GLH-20 that ...
Kashimura Tsutomu - - 2013
We treated a case that exhibited dissociation between blood flow in the transferred jejunum and the monitoring flap. The monitoring flap showed a false-negative, indicating blood flow to be favorable despite blood congestion in the transferred jejunum. The patient was a 69-year-old man. After tumor resection, reconstruction was performed with ...
Zhang Jia - - 2013
Monodisperse and uniform Y(6)O(5)F(8):RE(3+) (RE = Yb, Er, and Ho) microarchitectures with various morphologies have been constructed by a facile surfactant-assisted hydrothermal route, and their up-conversion luminescence and NIR quantum cutting properties were investigated. Hollow hexagonal prisms, microbundle gatherings by rods, and solid hexagonal prisms were designed by employing CTAB, ...
Pang Jincheng - - 2013
ABSTRACT: BACKGROUND: To determine the validity of a semi-automated segmentation of bone marrow lesions (BMLs) in the knee. METHODS: Construct validity of the semi-automated BML segmentation method was explored in two studies performed using sagittal intermediate weighted, turbo spine echo, fat-suppressed magnetic resonance imaging sequences obtained from the Osteoarthritis Initiative. ...
Altorf-van der Kuil Wieke - - 2013
BACKGROUND: Inverse associations between dietary protein and hypertension have been reported, which may be attributed to specific amino acids. OBJECTIVE: We examined whether the intake of glutamic acid, arginine, cysteine, lysine, or tyrosine was associated with blood pressure (BP) levels (n = 3086) and incident hypertension (n = 1810) in ...
Lacerra Giuseppina - - 2013
OBJECTIVES: To characterize the molecular basis of a β-thalassemia defect in subjects with mild microcytosis associated with normal Hb A2 and increased levels of Hb F. METHODS: Six subjects from 3 apparently unrelated families from Campania (Southern Italy) have been investigated by using DNA restriction analysis, Inverse PCR, cloning, sequencing, ...
Talipov Marat R - - 2013
HOON might be an elusive intermediate of atmospheric photochemical reactions of HONO or recombination of the parent nitrene HN and molecular oxygen. However, no reliable data on HOON structure and stability are available, and the nature of the O-O bond is not well understood. In this study, we used high-level ...
Nielsen Jakob V - - 2013
Hippocampal pyramidal neurons are important for encoding and retrieval of spatial maps and episodic memories. While previous work has shown that Zbtb20 is a cell fate determinant for CA1 pyramidal neurons, the regulatory mechanisms governing this process are not known. In this study, we demonstrate that Zbtb20 binds to genes ...
Cole Scott N - - 2013
Abstract Patient MW, a known confabulator, and healthy age-matched controls produced past and future events. Events were judged on emotional valence and plausibility characteristics. No differences in valence were found between MW and controls, although a positive emotional bias toward the future was observed. Strikingly, MW produced confabulations about future ...
Liimakka Satu - - 2013
Drawing on focus group discussions, this article explores how young, Finnish university students view the cultural ideals of health and appearance. The young adults noted how body practices aiming at health can turn into unhealthy obsessions. As a result, a healthy-looking body may serve to cover an underlying body image ...
Lo Yu-Lun - - 2013
Polyethylenimine (PEI) is one of the most potent synthetic gene delivery vectors because of its high transfection efficiency. Although PEI has been used as a delivery vehicle for a long while, its toxicity is always an issue for clinical applications. In this study, we introduced a low molecular weight PEI ...
Tzenov Youlian R - - 2013
The human papillomavirus (HPV) is the etiologic agent of cervical cancer. In this study, we provide evidence for the human Pygopus (hPygo)2 gene as a cellular biomarker for HPV-related disease. In a tumor microarray of cervical cancer progression, hPygo2 levels were greater in high-grade lesions and squamous cell carcinomas than ...
Dimke Henrik - - 2013
Kidney stones are a prevalent clinical condition imposing a large economic burden to the healthcare system. Hypercalciuria remains the major risk factor for development of a Ca(2+)-containing stone. The kidney's ability to alter Ca(2+) excretion in response to changes in serum Ca(2+) is in part mediated by the Ca(2+)-sensing receptor ...
García Felipe - - 2013
Combination antiretroviral therapy (cART) greatly improves survival and quality of life of HIV-1-infected patients; however, cART must be continued indefinitely to prevent viral rebound and associated disease progression. Inducing HIV-1-specific immune responses with a therapeutic immunization has been proposed to control viral replication after discontinuation of cART as an alternative ...
Seeger J B - - 2013
Aseptic loosening is the most common cause for revision unicompartmental knee arthroplasty and is associated with failure of the bone-cement or cement-implant interface. The purpose of the present study was to analyze different bone lavage techniques for the bone-cement and cement-implant interfaces of the femoral component and to study the ...
Arora Prem - - 2013
Objective To describe the clinical characteristics and outcomes of neonatal intensive care unit patients with a radiographic diagnosis of pneumatocele.Study Design Retrospective chart review.Results Our cohort (n = 27) had a gestational age of 27 ± 5 weeks, birth weight of 1038 ± 760 g, and a predominance of females (59%) and black infants (74%). All infants were ventilated at ...
Sousa Eduardo H S - - 2013
FixL is a prototype for heme-based sensors: multi-domain proteins that typically couple a histidine protein kinase activity to a heme-binding domain for sensing of diatomic gases such as oxygen, carbon monoxide and nitric oxide. Despite a relatively well-advanced knowledge of FixL, the importance of some of its domains has been ...
Nakasone Kiyoshi - - 2013
The brains of teleost fish exhibit remarkable sexual plasticity throughout their life span. To dissect the molecular basis for the development and reversal of sex differences in the teleost brain, we screened for genes differentially expressed between sexes in the brain of medaka (Oryzias latipes). One of the genes identified ...
Paciorkowski Alex R - - 2013
Some brain malformations have clinical and imaging features that are so specific they lend themselves readily to the diagnosis of a specific syndrome. The autosomal recessive pontocerebellar hypoplasias (PCH) fall into this category. These disorders feature postnatal progressive microcephaly combined with brainstem and cerebellar hemispheres that are hypoplastic at birth, ...
Kim Paul - - 2013
OBJECTIVE: To investigate the biological and technical success outcomes of implant-supported fixed dental prostheses with and without cantilevers, after a minimum of one year loading. MATERIAL AND METHODS: One hundred and seven subjects with 128 cantilever FDPs (cFDP) supported by 132 implants were compared with 99 individuals with 144 non-cantilever ...
Sartor M M - - 2013
Levels of residual disease (RD) are an independent predictor of progression-free survival (PFS) and overall survival (OS) in patients treated for chronic lymphocytic leukemia (CLL). We modified the international standardized approach (ISA) to RD detection using flow cytometry by developing a single tube 10 color antibody assay. METHOD: A single ...
Zaliaduonyte-Peksiene Diana - - 2013
INTRODUCTION: The development of left ventricular remodelling after acute myocardial infarction is a predictor of heart failure and mortality. The purpose of the present study was to assess whether the polymorphism of angiotensinogen (AGT) gene with threonine (T) instead of methionine (M) at amino acid 235 in exon 2 (M235T) ...
Murakami Jun - - 2013
The pond snail Lymnaea stagnalis is capable of learning taste aversion and consolidating this learning into long-term memory (LTM) that is called conditioned taste aversion (CTA). Previous studies showed that some molluscan insulin-related peptides (MIPs) were upregulated in snails exhibiting CTA. We thus hypothesized that MIPs play an important role ...
Bhat Jahangeer A - - 2013
ABSTRACT: BACKGROUND: Himalayan forests are the most important source of medicinal plants and other useful species for the local people. Kedarnath Wildlife Sanctuary (KWLS) is situated in the interior part of the Himalayan region. The presented study was carried in Madhmeshwar area of KWLS for the ecological status of plant ...
Duke Felicia D - - 2013
A formalin-fixed left, blue eye, from a 9-year-old, spayed female beagle dog was submitted to the Comparative Ocular Pathology Laboratory of Wisconsin (COPLOW) for light microscopic evaluation. The history included glaucoma and an abnormal appearance for 6 months and then the development of a uveal mass. The histologic diagnosis was a ...
Suzuki Hiroharu - - 2013
Hydrogen abstraction in the spotlight: UV irradiation (365 nm) of dinuclear ruthenium tetrahydride, [(Cp*Ru)(μ-H)(4) (RuCp*)] (Cp*=η(5) -C(5) Me(5) ), in a 2-alkanone, such as acetone or 2-butanone, resulted in the formation of dinuclear oxatrimethylenemethane complexes, [(Cp*Ru)(μ-η(3) :η(1) -CH(2) COCHR)(μ-H)(2) (RuCp*)] (R=H and CH(3) ), through hydrogen abstraction from the α ...
Turnipseed Sherri B - - 2013
The articles in this special issue of JAFC were originally presented at the 49th annual Florida Pesticide Residue Workshop (FPRW). The FPRW is an annual meeting for scientists specializing in trace level analysis of pesticides, veterinary drug residues, and other chemicals contaminants in food, animal feed, and environmental samples.
Chirinos Julio A - - 2013
Experimental studies implicate late systolic load as a determinant of impaired left-ventricular relaxation. We aimed to assess the relationship between the myocardial loading sequence and left-ventricular contraction and relaxation. Time-resolved central pressure and time-resolved left-ventricular geometry were measured with carotid tonometry and speckle-tracking echocardiography, respectively, for computation of time-resolved ejection-phase ...
Piantoni Giovanni - - 2013
The characteristic oscillations of the sleeping brain, spindles and slow waves, show trait-like, within-subject stability and a remarkable interindividual variability that correlates with functionally relevant measures such as memory performance and intelligence. Yet, the mechanisms underlying these interindividual differences are largely unknown. Spindles and slow waves are affected by the ...
Rossin Andrea - - 2013
Catalytic dehydrogenation of ammonia-borane (NH(3)·BH(3), AB) and dimethylamine borane (NHMe(2)·BH(3), DMAB) by the Pd(II) complex [((tBu)PCP)Pd(H(2)O)]PF(6) [(tBu)PCP = 2,6-C(6)H(3)(CH(2)P(t)Bu(2))(2)] leads to oligomerization and formation of spent fuels of general formula cyclo-[BH(2)-NR(2)](n) (n = 2,3; R = H, Me) as reaction byproducts, while one equivalent of H(2) is released per amine-borane ...
Cox Jason R - - 2013
Photoalignment of nematic liquid crystals is demonstrated using a di-π-methane rearrangement of a designed polymer. The alignment mechanism makes use of the strong coupling of the liquid crystal directors to dibenzobarrelene groups. The large structural changes that accompany photoisomerization effectively passivate segments of the polymer, allowing the remaining dibenzobarrelene groups ...
Hughes Joseph D - - 2013
To evaluate the use of general-purpose graphics processing units (GPGPUs) to improve the performance of MODFLOW, an unstructured preconditioned conjugate gradient (UPCG) solver has been developed. The UPCG solver uses a compressed sparse row storage scheme and includes Jacobi, zero fill-in incomplete, and modified-incomplete lower-upper (LU) factorization, and generalized least-squares ...
Li Yi - - 2013
The huge pool of hypothetical zeolites can be screened for likely candidates for successful targeted synthesis on the basis of a set of reliable criteria derived from the observation that the local interatomic distances in all existing zeolites strictly obey several rules. For example, the average TT and TO distances ...
Zaborowski Anthony Grant - - 2013
Abstract Purpose: To report a case of cytomegalovirus (CMV) retinitis in an HIV-negative, iatrogenically immunosuppressed patient with chronic uveitis following intravitreal triamcinolone acetonide (IVTA). Design: Observational case report. Methods: A 56-year-old female with chronic idiopathic panuveitis on azathioprine received a single 4-mg IVTA injection for macular edema and presented after ...
Perez-Lopez Araceli - - 2013
Salmonella infects and survives within B cells, but the mechanism used by the bacterium to promote its survival in these cells is unknown. In macrophages, flagellin secreted by Salmonella activates the Nod-like receptor (NLR) family CARD domain containing protein 4 (NLRC4) inflammasome, leading to the production of IL-1β and pyroptosis ...
Ryu Eun Sun - - 2013
Recent experimental and clinical studies suggest a causal role of uric acid in the development of chronic kidney disease. Most studies have focused on uric acid-induced endothelial dysfunction, oxidative stress and inflammation in the kidney. Direct effects of uric acid on tubular cells have not been studied in detail, and ...
Yang Albert C - - 2013
Bipolar disorder seasonality has been documented previously, though information on the effect of demographic and clinical variables on seasonal patterns is scant. This study examined effects of age, sex, index admission, and predominant polarity on bipolar disorder seasonality in a nationwide population. An inpatient cohort admitted to hospital exclusively for ...
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