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Flick Tawnya G TG Department of Chemistry, University of California, Berkeley, CA 94720-1460, - - 2013
With electrospray ionization from aqueous solutions, trivalent metal ions readily adduct to small peptides resulting in formation of predominantly (peptide + M(T) - H)(2+), where M(T) = La, Tm, Lu, Sm, Ho, Yb, Pm, Tb, or Eu, for peptides with molecular weights below ~1000 Da, and predominantly (peptide + M(T))(3+) ...
Ilchenko Serguei S Center for Proteomics and Bioinformatics, Case Western Reserve University, Cleveland, OH 44106, - - 2013
The study of protein kinetics requires an accurate measurement of isotopic ratios of peptides. Although Fourier transform-ion cyclotron resonance (FT-ICR) mass spectrometers yield accurate mass measurements of analytes, the isotopologue ratios are consistently lower than predicted. Recently, we demonstrated that the magnitude of the spectral error in the FT-ICR mass ...
Rogelj Joeri J Institute for Atmospheric and Climate Science, ETH Zurich, Universitätstrasse 16, CH-8092 Zürich, Switzerland. - - 2013
For more than a decade, the target of keeping global warming below 2 °C has been a key focus of the international climate debate. In response, the scientific community has published a number of scenario studies that estimate the costs of achieving such a target. Producing these estimates remains a challenge, ...
Rutz Erich E Murdoch Childrens Research Institute, The Royal Children's Hospital, Victoria, Australia. - - 2013
Gait and function may deteriorate with time in patients with spastic diplegia. Single-event multilevel surgery often is performed to either improve gait or prevent deterioration. However it is unclear whether the presumed gait improvements are durable. We therefore determined whether (1) single-event multilevel surgery improves gait in patients with spastic ...
Balthazart Jacques J GIGA Neurosciences, Research Group in Behavioral Neuroendocrinology, University of Liège, Liège, Belgium. - - 2013
Sexual behavior can be usefully parsed into an appetitive and a consummatory component. Both appetitive and consummatory male-typical sexual behaviors (respectively, ASB and CSB) are activated in male Japanese quail by testosterone (T) acting in the medial preoptic nucleus (POM), but never observed in females. This sex difference is based ...
Chen Lichao L Research Service, VA Boston Healthcare System, Brockton, MA, USA. - - 2013
Dysfunction of the orexin/hypocretin neurotransmitter system causes the sleep disorder narcolepsy, characterized by intrusion of rapid eye movement (REM) sleep-like events into normal wakefulness. The sites where orexins act to suppress REM sleep are incompletely understood. Previous studies suggested that the lateral pontomesencephalic tegmentum (lPMT) contains an important REM sleep ...
Micheli Fabrizio F Drug Design & Discovery, Aptuit Verona srl, Via A Fleming 4, 37135 Verona, Italy. - - 2013
The synthesis and characterization of new highly potent and selective dopamine (DA) D3 receptor antagonists has permitted to characterize the role of the DA D3 receptor in the control of drug-seeking behavior and in the pathophysiology of impulse control disorders and schizophrenia. In the present review, the authors will first ...
Imai Norio N Department of Orthopaedics Surgery, Niigata University Medical and Dental Hospital, 1-757 Asahimachidori, Niigata, Japan. - - 2013
Pelvic flexion affects orientation of the acetabular cup; however, pelvic position is not static in daily activities. During THA it is difficult to know the degree of pelvic flexion with the patient in the lateral position and that position is static. However, surgeons need to appropriately determine pelvic tilt to ...
Della Rocca Gregory J GJ Department of Orthopaedic Surgery, University of Missouri, 1 Hospital Drive, N116, DC053.10, Columbia, Missouri 65212, USA. - - 2013
Intimate partner violence (IPV)-physical, sexual, psychologic, or financial abuse between intimate partners-is the most common cause of nonfatal injury to women in North America. As many IPV-related injuries are musculoskeletal, orthopaedic surgeons are well positioned to identify and assist these patients. However, data are lacking regarding surgeons' knowledge of the ...
Bruni Danilo D Biomechanics and Technological Innovation Laboratory, Codivilla-Putti Research Center, Bologna University, Via Di Barbiano 1-10, 40136, Bologna, Italy. - - 2013
Although 7% to 38% of revision total knee arthroplasties (RTKAs) are attributable to prosthetic knee infections, controversy exists regarding the best surgical approach while reducing the risk of extensor mechanism complications and the reinfection rate. We compared The Knee Society Score(©) (KSS), incidences of complications, maximum knee flexion, residual extension ...
Watrous Jeramie D JD Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA, - - 2013
Mono- and multispecies microbial populations alter the chemistry of their surrounding environments during colony development thereby influencing multicellular behavior and interspecies interactions of neighboring microbes. Here we present a methodology that enables the creation of three-dimensional (3D) models of a microbial chemotype that can be correlated to the colony phenotype ...
Fan Lu L Centre for Marine Bio-Innovation and School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, NSW, - - 2013
Large-scale mortality of marine invertebrates is a major global concern for ocean ecosystems and many sessile, reef-building animals, such as sponges and corals, are experiencing significant declines through temperature-induced disease and bleaching. The health and survival of marine invertebrates is often dependent on intimate symbiotic associations with complex microbial communities, ...
Pascual-Font Aran A Department of Human Anatomy and Embryology I, School of Medicine, Complutense University of Madrid, Ciudad Universitaria s/n, 28040, Madrid, - - 2013
Since the 18th century, the existence of ulnar nerve innervation of the medial head of the triceps brachii muscle has been controversial. The evidence for or against such innervation has been based on macroscopic dissection, an unsuitable method for studying intraneural topography or intramuscular branching. The study of smaller specimens ...
Thaler Martin M Department of Orthopaedic Surgery, Medical University Innsbruck, Anichstr. 35, 6020 Innsbruck, Austria. - - 2013
Recently, a new minimally invasive technique called 'vertebral body stenting' (VBS) was introduced for the treatment of osteoporotic vertebral fractures. The technique was developed to prevent the loss of reduction after deflation of the balloon and to reduce the complication rate associated with cement leakage. The amount of kyphosis correction, ...
Josefson J L JL Division of Endocrinology, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois 60611-2605, USA. - - 2013
More than 40% of women with a normal pre-pregnancy body mass index (BMI) exceed the 2009 Institute of Medicine (IOM) guidelines' recommended weight gain of 25-35 lb. Excessive gestational weight gain is one modifiable factor that may be contributing to childhood overweight and obesity. The objective of this study was to ...
Thomasy Sara M SM Veterinary Medical Teaching Hospital School of Veterinary Medicine, University of California-Davis, CA 95616, USA. - - 2013
A 16-year-old spayed female cat was evaluated for lagophthalmos and chronic exposure keratitis in both eyes. Ophthalmic examination revealed upper and lower eyelid entropion of the left eye (OS) and markedly decreased retropulsion, restricted eye movement, marked episcleral congestion, and severe keratitis of both eyes (OU). Magnetic resonance imaging of ...
Cheng Shigang S Department of Pediatric Surgery, Hubei Women and Children's Hospital, Wuhan, 430070, People's Republic of - - 2013
Successful culturing of neurons from adult animals has been historically difficult for a relatively long time. In this study, we reported the development of a novel method for the isolation and the culture of major pelvic ganglion (MPG) neurons from adult rat. The cultured cells were identified by neuron morphology ...
Villanueva Càndid C Gastrointestinal Bleeding Unit, Department of Gastroenterology, Hospital de Sant Pau, Autonomous University, Barcelona, Spain. - - 2013
The hemoglobin threshold for transfusion of red cells in patients with acute gastrointestinal bleeding is controversial. We compared the efficacy and safety of a restrictive transfusion strategy with those of a liberal transfusion strategy. We enrolled 921 patients with severe acute upper gastrointestinal bleeding and randomly assigned 461 of them ...
Crutchfield Christopher A CA National Institutes of Health, Bethesda, MD 20892, - - 2013
We have developed new applications of the pseudocolor plot for the analysis of LC/MS data. These applications include spectral averaging, analysis of variance, differential comparison of spectra, and qualitative filtering by compound class. These applications have been motivated by the need to better understand LC/MS data generated from analysis of ...
Kim Hoseok - - 2013
The cortico-basal ganglia network has been proposed to consist of parallel loops serving distinct functions. However, it is still uncertain how the content of processed information varies across different loops and how it is related to the functions of each loop. We investigated this issue by comparing neuronal activity in ...
Tsui David - - 2013
The transcription factor FoxP2 has been associated with the development of human speech but the underlying cellular function of FoxP2 is still unclear. Here we provide evidence that FoxP2 regulates genesis of some intermediate progenitors and neurons in the mammalian cortex, one of the key centers for human speech. Specifically, ...
Seow Swee-Chong - - 2013
AIMS: Persistent left superior vena cava (PLSVC) is found in 0.3-2% of the population. Pacemaker implant in PLSVC can be technically challenging. Most operators have hitherto manipulated ventricular leads through the coronary sinus (CS) into the right ventricle (RV). In this case series, we describe the use of standard passive ...
Brookwell M L - - 2013
BACKGROUND: Cognitive models have postulated that auditory hallucinations arise from the misattribution of internally generated cognitive events to external sources. Several experimental paradigms have been developed to assess this externalizing bias in clinical and non-clinical hallucination-prone samples, including source-monitoring, verbal self-monitoring and auditory signal detection tasks. This meta-analysis aims to ...
Velasco Román Pérez - - 2013
ABSTRACT: BACKGROUND: Thailand faces a significant burden in terms of treating and managing degenerative and chronic diseases. Moreover, incidences of rare diseases are rising. Many of these---such as diabetes, cancer, and inherited inborn metabolic diseases---have no definite treatments or cure. Meanwhile, advanced health biotechnology has been found, in principle, to ...
Bayon Yves - - 2013
Industry Day Symposium -Tissue Engineering and Regenerative Medicine International Society World Congress: Summary Report: Vienna, Austria/ September 5-8, 2012.
Agarwala Anandita - - 2013
A cloned transgenic minipig model of hypercholesterolemia and accelerated atherosclerosis could accelerate discovery of new therapies for atherosclerotic cardiovascular disease (Al-Mashhadi et al., this issue).
Campo Giuseppe M - - 2013
Investigations have suggested degradation of native hyaluronan (HA) into small oligosaccharides as being involved in the development and progression of inflammatory diseases, particularly rheumatoid arthritis (RA). Inflammatory responses occur by modulating the TLR4 and 2, and the CD44 natural HA receptor. As reported recently, the adenosine A2 receptor (A(2A)R) plays ...
Bere Elling - - 2013
Aims: The purpose of this study is to assess the relationships between trips in nature, gathering of wild plants, fishing and hunting and weight status. Methods: Data from a cross-sectional questionnaire survey of 996 parents of sixth- and seventh-graders from 38 randomly chosen schools in two Norwegian counties. All data ...
Saber-Ayad Maha M - - 2013
BACKGROUND: The renin-angiotensin-aldosterone system plays a role in physiological and pathological responses of the heart to both static and dynamic exercise. Previous studies showed that the level of angiotensin II is determined by the angiotensin-converting enzyme insertion/deletion (ACE I/D) polymorphism.Aim:We aimed in this study to determine the effect of ACE ...
Langseth Eirin - - 2013
A Missing Gold Link: An Au(III) alkene complex has been prepared and characterized by NMR spectroscopy and X-ray crystallography. Its bonding features have been analyzed by DFT calculations and natural bond orbital (NBO) analysis. In [(cod)AuMe(2) ](+) , the unequal AuC bond lengths result from the domination of the preference ...
Moghissi Keyvan - - 2013
A 63-year old woman diagnosed in September 2001 with a typical bronchial carcinoid of the left upper lobe bronchus extending into the left main stem bronchus is presented. The patient was unsuitable for standard surgical treatment, and the topography was not amenable for a parenchyma-saving bronchoplastic procedure. Two cycles of ...
Zhang Fan - - 2013
This study examined the mechanisms underlying the effects of sacral neuromodulation on reflex bladder activity in chloralose anesthetized cats. Bladder activity was recorded during cystometrograms (CMGs) or under isovolumetric conditions. S1-S3 dorsal (DRT) or ventral root (VRT) were electrically stimulated at a range of frequencies (1-30 Hz) and at intensities ...
Ashley Jeffrey T F - - 2013
In children, omega-3 polyunsaturated fatty acids (PUFAs) may elicit a suite of health benefits including enhancement of cognitive development. Subsequently, dietary supplements containing omega-3 PUFAs have become increasingly popular. Often, the largest source of beneficial PUFAs in these supplements is fish oil, which may contain significant levels of contaminants such ...
Huang Tzung-Chi - - 2013
ABSTRACT: Background and purpose: Currently, the inhomogeneity of the pulmonary function is not considered when treatment plans are generated in thoracic cancer radiotherapy. This study evaluates the dose of treatment plans on highly-functional volumes and performs functional treatment planning by incorporation of ventilation data from 4D-CT.Materials and methods: Eleven patients ...
De Soumen Das - - 2013
Upper-extremity-specific disability correlates with mood and coping strategies. The aim of this study was to determine if two psychological factors, kinesiophobia (fear of movement) and perceived partner support, contribute significantly to variation in upper-extremity-specific disability in a model that included factors known to contribute to variation such as depression, pain ...
Jeon Tae Yoon - - 2013
Large-area, highly ordered, Ag nanostructured arrays with various geometrical features were prepared for use as surface-enhanced Raman scattering (SERS)-active substrates by the self-assembly of inorganic particles on an SU-8 surface, followed by particle embedding and Ag vapor deposition. By adjusting the embedding time of the inorganic particles, the size of ...
Gu Zhaolin - - 2013
Immovable historical relics in some archaeology museums of China suffer deterioration due to their improper preservation environment. The existing environmental control systems used in archaeology museums are often designed for the amenities of visitors; and these manipulated environments are often inappropriate for the conservation of abiotic relics. This paper points ...
Li Jiarui - - 2013
Cell aggregation in unicellular organisms, induced by either cell non-sexual adhesion to yield flocs and biofilm, or pheromone-driving sexual conjugation is of great significance in cellular stress response, medicine, and brewing industries. Most current literatures have focused on one form of cell aggregation termed flocculation and its major molecular determinants, ...
Zhang Tengyue - - 2013
ABSTRACT: BACKGROUND: Mounting evidence has suggested that plasminogen activator inhibitor-1 (PAI-1) is a candidate for increased risk of diabetic retinopathy. Studies have reported that insertion/deletion polymorphism in the PAI-1 gene may influence the risk of this disease. To comprehensively address this issue, we performed a meta-analysis to evaluate the association ...
Ran Xiang - - 2013
We demonstrate a novel, rapid and label-free assay for the detection of Ag(+) and biothiols with high sensitivity and selectivity by utilization of Ag nanoparticle-decorated graphene quantum dots.
Boucoiran Isabelle - - 2013
Objectives To determine whether the parameters used in first-trimester screening for aneuploidies contribute significantly to the prediction of birth weight.Methods In this retrospective cohort study (n = 4110), nuchal translucency (NT), free β-chorionic gonadotropin (fβ-hCG), and pregnancy-associated plasma protein-A (PAPP-A) blood concentrations were measured between 11 + 0 and 13 + 6 weeks. Multiple pregnancies, chromosomal anomalies, major ...
Rawy Sayed M - - 2013
This study was designed to investigate the reproductive toxicity of aluminium sulphate and the therapeutic effects of administration of zinc sulphate and vitamin E individually or in combination against the toxic effect caused by aluminium (Al) in male albino rats. The animals were divided into five groups: group 1 received ...
Turner C - - 2013
Context:Several trials have reported an increased risk of fractures and falls after intermittent high-dose vitamin D. Treatment with loading doses of vitamin D may increase 1,25(OH)(2) vitamin D catabolism through changes in calcium/phosphate homeostasis and fibroblast growth factor-23 (FGF-23).Objective:The aim was to determine the effects of high-dose vitamin D on ...
Ben-Simon Avi - - 2013
The assembly of mixtures of nanoparticles with different properties into a binary nanoparticle superlattice (BNSL) provides a route to fabricate novel classes of materials with properties emerging from the choice of the building blocks. The common theoretical approach based on the hard-spheres model predicts crystallization of only a few metastable ...
Smith Jodi M - - 2013
The NAPRTCS transplant registry has collected clinical information on children undergoing kidney transplantation since 1987 and now includes information on 11 603 kidney transplants in 10 632 patients. Since the first data analysis in 1989, NAPRTCS reports have documented marked improvements in outcome after kidney transplantation in addition to identifying factors associated ...
Tziortzi Andri C - - 2013
The striatum acts in conjunction with the cortex to control and execute functions that are impaired by abnormal dopamine neurotransmission in disorders such as Parkinson's and schizophrenia. To date, in vivo quantification of striatal dopamine has been restricted to structure-based striatal subdivisions. Here, we present a multimodal imaging approach that ...
Al-Musawi Sara L - - 2013
Oocyte-derived bone morphogenetic protein 15 (BMP15) regulates ovulation rate and female fertility in a species-specific manner, being important in humans and sheep and largely superfluous in mice. To understand these species differences, we have compared the expression and activity of human, murine, and ovine BMP15. In HEK293F cells, human BMP15 ...
Hwang Sun-Young - - 2013
In RNA virus-infected cells, retinoic acid-inducible gene-I-like receptors (RLRs) sense foreign RNAs and activate signaling cascades to produce IFN-α/β. However, not every infected cell produces IFN-α/β that exhibits cellular heterogeneity in antiviral immune responses. Using the IFN-β-GFP reporter system, we observed bimodal IFN-β production in the uniformly stimulated cell population ...
Westermeyer Hans D - - 2013
An 8-year-old, brachycephalic, mixed breed cat underwent full mouth tooth extractions for the treatment of tooth root abscessation. Subsequently, the cat developed anterior uveitis refractory to topical therapy that eventually necessitated enucleation. Actinomyces species were isolated from both the tooth root abscesses and the anterior chamber after enucleation. Histopathology of ...
Su Dada - - 2013
BACKGROUND: Ovarian cancer is an important neoplasm that is difficult to diagnose and treat; therefore, prevention is the preferable strategy. Growing evidence indicates a protective effect of breastfeeding on ovarian cancer risk. OBJECTIVE: The objective was to investigate the association between lactation and the risk of ovarian cancer among southern ...
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