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Results 351 - 400 of 3304
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Kikuchi-Utsumi Kazue - - 2013
Methamphetamine (METH) is a psychostimulant that damages nigrostriatal dopaminergic terminals, primarily by enhancing dopamine and glutamate release. α(1)-adrenergic receptor (AR) subtype involved in METH-induced neurotoxicity in rats was investigated using selective α(1)-AR antagonists. METH neurotoxicity was evaluated by (1) measuring body temperature; (2) determining tyrosine hydroxylase (TH) immunoreactivity levels; (3) ...
Yoo Hana - - 2013
Children's empathy and prosocial behavior play an important role in their social competence. Of the influential factors, research has demonstrated that parental behaviors and the quality of the parent-child relationship are important correlates of children's development of empathy and prosocial behavior. The current study examined the associations between different types ...
Singh Satyavan - - 2013
Field experiments were conducted in open top chamber during rabi seasons of 2009-10 and 2010-11 at the research farm of the Indian Agricultural Research Institute, New Delhi to study the effect of tropospheric ozone (O(3)) and carbon dioxide (CO(2)) interaction on yield and nutritional quality of Indian mustard (Brassica juncea ...
Bornot Aurelie - - 2013
The traditional drug discovery strategy of pursuing "one compound - one target" has had difficulties delivering novel therapies for complex diseases currently lacking adequate treatments. An alternative and complementary approach is the design of multi-targeted modulators simultaneously addressing multiple pathological mechanisms or overcoming pathway robustness. In this study, we propose ...
Gupta Ravi - - 2013
Our clinical experience suggested existence of a third group, stage-independent-OSA besides two known groups: REM-dependent-OSA and NREM-dependent-OSA. This study was planned to compare the characteristics of this group with the other two. All the subjects undergoing diagnostic video-polysomnographies with AHI >5/h were included in this study. Based upon the ratio of ...
Wu Chia-Ming - - 2013
A MOF-5 [Zn(4)O(BDC)(3); BDC = 1,4-benzenedicarboxylate]@SBA-15 hybrid material has been prepared by using SBA-15 as a matrix. This hybrid material exhibits improved hydrostability under ambient conditions and unique gas adsorption behavior compared with pristine MOF-5.
Cowper-Smith Christopher D - - 2013
Objective: To determine if cochlear implant (CI) patients exhibit a temporal processing deficit for auditory stimuli, by examining refractory effects of the N1 event-related potential (ERP) component. Design: CI patients and normally-hearing controls were tested in an auditory refractory period paradigm while ERP recordings were collected across the scalp. Participants ...
Ch'ng Ewe Seng - - 2013
Tumor-associated macrophages play a crucial role in breast cancer progression and tumor angiogenesis. However, evaluation of tumor-associated macrophages incorporating their histological locations is lacking. The aim of this study was to clarify whether macrophages in tumor stroma and macrophages in tumor cell nests have distinctive properties in relation to pertinent ...
Kitaguchi Tetsuya - - 2013
Intracellular cAMP and Ca2+ are important second messengers that regulate insulin secretion in pancreatic β cells. However, the molecular mechanism underlying their mutual interaction for exocytosis is not fully understood. In this study, we investigated the interplay between intracellular cAMP and Ca2+ concentrations ([cAMP]i and [Ca2+]i, respectively) in the pancreatic ...
Hemami Hooshang - - 2013
A basal ganglia central pattern generator (CPG) is developed and its role in voluntary movements on the ground and postural reactions on a disturbed platform are studied and analysed by simulation. Biped dynamics and platform kinematics are utilised. The effects of agonist-antagonist muscular co-activation and joint stiffness are formulated. The ...
Niazi Imran Khan IK Department of Health Science and Technology, Center for Sensory-Motor Interaction, Aalborg University, Aalborg, - - 2013
To allow a routinely use of brain-computer interfaces (BCI), there is a need to reduce or completely eliminate the time-consuming part of the individualized training of the user. In this study, we investigate the possibility of avoiding the individual training phase in the detection of movement intention in asynchronous BCIs ...
Wu Mingxing - - 2013
The dye-sensitized solar cells (DSCs) using SnO(2) and Nb(2)O(5) counter electrodes (CEs) prepared in N(2) atmosphere yielded power conversion efficiencies (PCE) of 6.09% and 4.65%, much higher than the PCE values (1.84%, 0.97%) of the DSCs using the same SnO(2) and Nb(2)O(5) CEs prepared in air.
Fravolini M L - - 2013
This paper proposes a scheme for the control of the blood glucose in subjects with type-1 diabetes mellitus based on the subcutaneous (s.c.) glucose measurement and s.c. insulin administration. The tuning of the controller is based on an iterative learning strategy that exploits the repetitiveness of the daily feeding habit ...
Vanderoost Jef - - 2013
Resorption cavities formed during the bone remodelling cycle change the structure and thus the mechanical properties of trabecular bone. We tested the hypotheses that bone stiffness loss due to resorption cavities depends on anatomical location, and that for identical eroded bone volumes, cavities would cause more stiffness loss than homogeneous ...
Yazyev Oleg V - - 2013
Graphene nanoribbons (GNRs) are one-dimensional nanostructures predicted to display a rich variety of electronic behaviors. Depending on their structure, GNRs realize metallic and semiconducting electronic structures with band gaps that can be tuned across broad ranges. Certain GNRs also exhibit a peculiar gapped magnetic phase for which the half-metallic state ...
Dolister Michael - - 2013
Purpose: Central venous catheters (CVCs) are often placed to resuscitate unstable emergency department (ED) patients. In an observational study, we assessed intraosseous (IO) vascular access in the hospital, and compared results to published experiences with CVC placement. 
Methods: Patients who would typically receive a CVC were considered for the study. ...
Antoniu Sabina Antonela - - 2013
In asthma and chronic obstructive pulmonary disease (COPD), the inflammation in the airways cannot always be controlled with conventional therapies, such as inhaled corticosteroids. Addition of more specific anti-inflammatory therapies, such as monoclonal antibodies, against inflammation pathways might improve the disease outcome. This review individually discusses the major inflammation pathways ...
Delgado M - - 2013
The main aim of this study was to evaluate the toxicity of different poultry manure landfill leachates, using a well-known toxicity test system (MS3). The bioassay was made using a battery of toxicity tests including acute toxicity with crustacean (Daphnia magna), algae (Chlorella vulgaris) and the in vitro toxicity test ...
Matsushita Satoshi - - 2013
This review presents recent advances in the synthesis, electrochemical properties, and optical functions of poly(3,4-ethylenedioxythiophene) (PEDOT) derivatives embodying chirality and liquid crystallinity. Various methods for preparing the optically active and liquid crystalline (LC) PEDOT derivatives, such as (i) the introduction of chiral substituents into polymer side chains, (ii) chemical or ...
Slater Robert A - - 2013
BACKGROUND: The possible effect of random intra-site placement on the outcome of the Semmes-Weinstein monofilament (SWF) test is not known. We sought to determine the significance of this variable in the diagnosis of loss of protective sensation (LOPS) in patients with diabetes. METHODS: Forty-five patients with diabetes with history of ...
Li Chen - - 2013
This study aims to investigate the expression and significance of KPNA2 in human gastric adenocarcinoma progression and prognosis. Using immunohistochemistry and real-time reverse transcriptase polymerase chain reaction assay, we identified abnormally elevated expression of KPNA2 in gastric adenocarcinoma tissues compared to paired normal stomach mucosa tissues in 30 patients (p < 0.05). ...
Al-Mashhadi Rozh H - - 2013
Lack of animal models with human-like size and pathology hampers translational research in atherosclerosis. Mouse models are missing central features of human atherosclerosis and are too small for intravascular procedures and imaging. Modeling the disease in minipigs may overcome these limitations, but it has proven difficult to induce rapid atherosclerosis ...
Casassus Simon - - 2013
The formation of gaseous giant planets is thought to occur in the first few million years after stellar birth. Models predict that the process produces a deep gap in the dust component (shallower in the gas). Infrared observations of the disk around the young star HD 142527 (at a distance of ...
Philips Jo - - 2013
Microbial dechlorination of trichloroethene (TCE) is inhibited at elevated TCE concentrations. A batch experiment and modeling analysis were performed to examine whether this self-inhibition is related to an enhanced cell decay or a reduced dechlorination activity at increasing TCE concentrations. The batch experiment combined four different initial TCE concentrations (1.4 ...
Heo Seongkum S 1University of Arkansas for Medical Sciences, College of Nursing, - - 2013
Patients with heart failure (HF) have poor health-related quality of life (HRQOL). The vast majority of patients have physical symptoms, and about 30-40% have depressive symptoms. The combined effects of physical and depressive symptoms on HRQOL have not been examined fully in HF. To examine the combined effects of physical ...
Schenkein Harvey A HA Department of Periodontics, School of Dentistry, Virginia Commonwealth University, Richmond, VA 23298-0566, USA. - - 2013
Periodontal diseases are associated with a variety of systemic diseases, including cardiovascular disease and stroke, and patients with periodontitis demonstrate elevated levels of anti-cardiolipin antibodies. We sought to determine if anti-cardiolipin antibodies from periodontitis patients induced monocyte chemotactic protein-1 production by human vascular endothelial cells. IgG was purified from sera ...
Martin L - - 2013
The main objective of this work was to establish a mathematical function that correlates pesticide residue levels in apple juice with the levels of the pesticides applied on the raw fruit, taking into account some of their physicochemical properties such as water solubility, the octanol/water partition coefficient, the organic carbon ...
Qi Yiping - - 2013
Improved methods for engineering sequence-specific nucleases, including zinc finger nucleases (ZFNs) and TAL effector nucleases (TALENs), have made it possible to precisely modify plant genomes. However, the success of genome modification is largely dependent on the intrinsic activity of the engineered nucleases. In this study, we sought to enhance ZFN-mediated ...
Carrara Davide - - 2013
INTRODUCTION: Vitamin D plasma levels are negatively associated with blood pressure and cardiovascular mortality, and vitamin D supplementation reduces cardiovascular events. Renin-angiotensin system (RAS) suppression may be one of the mechanisms involved. However, there are no interventional prospective studies demonstrating a reduction in circulating RAS components after vitamin D treatment. ...
Jia Xiaoxuan - - 2013
Neural activity in the gamma frequency range ("gamma") is elevated during active cognitive states. Gamma has been proposed to play an important role in cortical function, although this is debated. Understanding what function gamma might fulfill requires a better understanding of its properties and the mechanisms that generate it. Gamma ...
Langseth Eirin - - 2013
A Missing Gold Link: An Au(III) alkene complex has been prepared and characterized by NMR spectroscopy and X-ray crystallography. Its bonding features have been analyzed by DFT calculations and natural bond orbital (NBO) analysis. In [(cod)AuMe(2) ](+) , the unequal AuC bond lengths result from the domination of the preference ...
Moghissi Keyvan - - 2013
A 63-year old woman diagnosed in September 2001 with a typical bronchial carcinoid of the left upper lobe bronchus extending into the left main stem bronchus is presented. The patient was unsuitable for standard surgical treatment, and the topography was not amenable for a parenchyma-saving bronchoplastic procedure. Two cycles of ...
Kowalska Irina I Department of Endocrinology, Diabetology, and Internal Medicine, Medical University of Bialystok, M.C. Sklodowskiej 24a, 15-276 Bialystok, - - 2013
Serum visfatin is elevated in insulin-resistant states, ie, obesity, type 2 diabetes mellitus, and polycystic ovary syndrome, thus linking visfatin with the pathogenesis of insulin resistance. Our objective was to evaluate the effect of hyperinsulinemia and the acute elevation of free fatty acids (FFAs) on serum visfatin in humans. We ...
Zhang Fan - - 2013
This study examined the mechanisms underlying the effects of sacral neuromodulation on reflex bladder activity in chloralose anesthetized cats. Bladder activity was recorded during cystometrograms (CMGs) or under isovolumetric conditions. S1-S3 dorsal (DRT) or ventral root (VRT) were electrically stimulated at a range of frequencies (1-30 Hz) and at intensities ...
Ashley Jeffrey T F - - 2013
In children, omega-3 polyunsaturated fatty acids (PUFAs) may elicit a suite of health benefits including enhancement of cognitive development. Subsequently, dietary supplements containing omega-3 PUFAs have become increasingly popular. Often, the largest source of beneficial PUFAs in these supplements is fish oil, which may contain significant levels of contaminants such ...
Pham Thanh H - - 2013
DNA-dependent activator of interferon regulatory factor (DAI) acts as a cytosolic B-form DNA sensor that induces type I interferons. However, DAI is not required for DNA sensing in certain cell types due to redundancy of the DNA sensing system. Here, we investigated the effect of DAI on herpes simplex virus ...
Sivay Mariya V - - 2013
The rarely identified influenza A viruses of the H15 hemagglutinin subtype have been isolated exclusively in Australia. Here we report the isolation of an H15N4 influenza A virus (A/teal/Chany/7119/2008) in Western Siberia, Russia. Phylogenetic analysis demonstrated that the internal genes of the A/teal/Chany/7119/2008 strain belong to the Eurasian clade and ...
Huang Tzung-Chi - - 2013
ABSTRACT: Background and purpose: Currently, the inhomogeneity of the pulmonary function is not considered when treatment plans are generated in thoracic cancer radiotherapy. This study evaluates the dose of treatment plans on highly-functional volumes and performs functional treatment planning by incorporation of ventilation data from 4D-CT.Materials and methods: Eleven patients ...
Haack Karla K V KK Nebraska Medical Center, Omaha, NE, - - 2013
The small GTPase RhoA and its associated kinase ROCKII are involved in vascular smooth muscle cell contraction and endothelial NO synthase mRNA destabilization. Overactivation of the RhoA/ROCKII pathway is implicated in several pathologies, including chronic heart failure (CHF), and may contribute to the enhanced sympathetic outflow seen in CHF as ...
- - 2013
I like refereeing because I can help to improve the quality of science. My favorite place on earth is somewhere in the mountains.
Bakker Mirte J - - 2013
The nature of culture-specific startles syndromes such as "Latah" in Indonesia and Malaysia is ill understood. Hypotheses concerning their origin include sociocultural behavior, psychiatric disorders, and neurological syndromes. The various disorders show striking similarities despite occurring in diverse cultural settings and genetically distant populations. They are characterized clinically by exaggerated ...
Eichenlaub Jean-Baptiste - - 2013
The neurophysiological correlates of dreaming remain unclear. According to the "arousal-retrieval" model, dream encoding depends on intrasleep wakefulness. Consistent with this model, subjects with high and low dream recall frequency (DRF) report differences in intrasleep awakenings. This suggests a possible neurophysiological trait difference between the 2 groups. To test this ...
Long Changbai - - 2013
High temperature Aurivillius piezoelectrics, (Li, Ln)(0.06)(Na, Bi)(0.44)Bi(2)Nb(2)O(9) (NBN-LiLn), with Li and Ln (Ce, Nd, La and Y) co-substitution at the A site, were prepared using a solid-state reaction process. Taking cation disordering between A site and the (Bi(2)O(2))(2+) layers into consideration, the crystal structure of (Li, Nd)(0.06)(Na, Bi)(0.44)Bi(2)Nb(2)O(9) (NBN-LiNd) was ...
Paul Sumita - - 2013
The objective of this investigation was to design and develop water-in-oil-in-water type multiple emulsions (w/o/w emulsions) entrapping acyclovir for improving its oral bioavailability. Multiple emulsions (MEs) were prepared and optimized using Span-80 and Span-83 as lipophilic surfactant and Brij-35 as hydrophilic surfactant. The physio-chemical properties of the w/o/w emulsions - ...
Nakash Ora - - 2013
We examined the characteristics of therapists' implicit clinical judgments during the mental health intake. Following the intake sessions with new clients, we conducted 129 semistructured interviews with 47 therapists. We found that 82% of therapists and 75% of interviews included reference to implicit clinical judgments. Therapists referred to these judgments ...
Lücking Vibeke - - 2013
The purpose was to identify risk factors for bacteremia in febrile episodes occurring during chemotherapy for acute lymphoblastic leukemia (ALL) in children, and to develop a risk score permitting risk-adapted antibiotic therapy. We reviewed a total of 172 febrile episodes occurring during chemotherapy in 31 children and adolescents with ALL. ...
Gaur Praveen Kumar - - 2013
Abstract Context: Transdermal formulations contain permeation enhancer which causes skin damage. Ceramide 2 is natural lipid found in stratum corneum (SC). Objective: Drug-loaded nanovesicles of ceramide-2, cholesterol, palmitic acid, cholesteryl sulfate were formulated and analyzed for physical and biological properties. Diclofenac was used as a model drug. Materials and method: ...
Mazer-Amirshahi Maryann - - 2013
PURPOSE: Adverse drug reactions, including overdose are a major cause of morbidity and mortality, yet clinical toxicology data is limited at the time of drug approval. This study was conducted to determine the quality of clinical toxicology data available for newly approved pharmaceuticals and time to labeling revisions. METHODS: The ...
Brenneis Christian C F.M. Kirby Neurobiology Center, Children's Hospital Boston, Boston, Massachusetts 02115, - - 2013
Specific somatosensations may be processed by different subsets of primary afferents. C-fibers expressing heat-sensitive TRPV1 channels are proposed, for example, to be heat but not mechanical pain detectors. To phenotype in rats the sensory function of TRPV1(+) afferents, we rapidly and selectively silenced only their activity, by introducing the membrane-impermeant ...
Lacerra Giuseppina - - 2013
OBJECTIVES: To characterize the molecular basis of a β-thalassemia defect in subjects with mild microcytosis associated with normal Hb A2 and increased levels of Hb F. METHODS: Six subjects from 3 apparently unrelated families from Campania (Southern Italy) have been investigated by using DNA restriction analysis, Inverse PCR, cloning, sequencing, ...
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