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Aoki Yusuke - - 2013
The anthraquinone-sialic acid hybrids designed effectively degraded not only non-drug-resistant neuraminidase but also drug-resistant neuraminidase, which is an important target of anti-influenza therapy. Degradation was achieved using long-wavelength UV radiation in the absence of any additives and under neutral conditions. Moreover, the hybrids efficiently inhibited neuraminidase activities upon photo-irradiation.
Durmus Dilek - - 2013
The aim of this trial is to investigate and compare the effects of phonophoresis (PP) and ultrasound (US) therapy on pain, disability, trunk muscle strength, walking performance, spinal mobility, quality of life (QOL), and depression in the patients with chronic low back pain (CLBP). A total of 60 patients with ...
Shi Qi - - 2013
Caveolin-1 is one of the major constituents of caveolae. Both Cav-1 and PrP are plasma membrane proteins, which show active capacities for molecular interactions with many other proteins or agents, including themselves. Using yeast two-hybrid system and immunoprecipitation, we reconfirmed the molecular interaction between human Cav-1 and PrP. With co-immunoprecipitation ...
Shang Youjun - - 2013
ABSTRACT: BACKGROUND: We examined differences in pathogenicity in pigs from China that had been experimentally infected with porcine reproductive and respiratory syndrome virus (PRRSV). METHODS: We compared pathogenic characteristics of a field isolate (GX-1/2008F), two PRRSV isolates (HN-1/2008, YN-1/2008) propagated in cells, and GX-1/2008F that had been propagated in cells ...
Andersson Karl-Erik - - 2013
Abstract When the currently available pharmacotherapeutic principles used for treatment of male lower urinary tract symptoms (LUTS) fail, transurethral resection of the prostate still remains the widely applied gold-standard therapy, since the majority of minimally invasive therapies have not achieved the same efficacy and/or lack an evidence base to support ...
Kalcioglu M Tayyar - - 2013
Bone cement is a good and cheap option for some ossicular chain problems such as incudostapedial re-bridging. The purpose of this retrospective study is to evaluate the audiologic results after reconstruction of three different types of ossicular chain defects, using bone cement. Group 1 consists of 42 patients who underwent ...
Pokrywczynska Marta - - 2013
Diabetes mellitus is one of the most serious public health challenges of the twenty-first century. Allogenic islet transplantation is an efficient therapy for type 1 diabetes. However, immune rejection, side effects of immunosuppressive treatment as well as lack of sufficient donor organs limits its potential. In recent years, several promising ...
Carretti Ettore - - 2013
The nucleus of the Milky Way is known to harbour regions of intense star formation activity as well as a supermassive black hole. Recent observations have revealed regions of γ-ray emission reaching far above and below the Galactic Centre (relative to the Galactic plane), the so-called 'Fermi bubbles'. It is ...
Kjær Trille - - 2013
Objectives. Survivors of squamous cell carcinoma of the head and neck (HNSCC) are more severely affected in regard to affiliation to the work market than other cancer survivors. Few studies have investigated associations between socioeconomic and disease-related factors and work market affiliation after curative treatment of HNSCC. We investigated the ...
Regueiro Maria - - 2013
Given the importance of Y-chromosome haplogroup Q to better understand the source populations of contemporary Native Americans, we studied 8 biallelic and 17 microsatellite polymorphisms on the background of 128 Q Y-chromosomes from geographically targeted populations. The populations examined in this study include three from the Tuva Republic in Central ...
Barker Ian A - - 2013
Triarylsulfonium hexafluorophosphate salts were shown to be effective catalysts for the ring-opening polymerisation of various cyclic monomers under UV irradiation. A dual basic/acidic catalytic system demonstrated the potential for UV-triggered formation of poly(δ-valerolactone)-b-poly(l-lactide)-b-poly(δ-valerolactone) in a 'one-pot' reaction.
Kassab Yaman - - 2013
Background Secondary prevention pharmacotherapy improves outcomes after acute coronary syndrome (ACS). However, poor medication adherence is common, and various factors play a role in adherence. Objectives The purpose of this study was to evaluate patients' level of adherence to evidence-based therapies at an average of 6 months after discharge for ACS ...
Signoret Carine - - 2013
Recent human behavioral studies have shown semantic and/or lexical processing for stimuli presented below the auditory perception threshold. Here, we investigated electroencephalographic responses to words, pseudo-words and complex sounds, in conditions where phonological and lexical categorizations were behaviorally successful (categorized stimuli) or unsuccessful (uncategorized stimuli). Data showed a greater decrease ...
Mee Jf - - 2013
The objective of the present study was to elicit opinion from two groups of veterinarians [subject matter experts and non-subject matter experts] about the causes of bovine perinatal mortality and the criteria used to assign such causes. The subject matter experts were selected on the basis of their scientific publications ...
Matsumoto Tracie K - - 2013
KEY MESSAGE : There are multiple publications on Anthurium transformation, yet a commercial product has not been achieved. This may be due to use of non-optimum promoters here we address this problem. Different promoters and tissue types were evaluated for transient β-glucuronidase (GUS) expression in Anthurium andraeanum Hort. 'Marian Seefurth' ...
Ismail Ismail Ahmed - - 2013
Since epithelial-mesenchymal transition (EMT) plays a critical role in cancer progression and in maintaining cancer stem cell properties, EMT is emerging as a therapeutic target for inhibiting the metastatic progression of cancer cells. 2'-Hydroxycinnamaldehyde (HCA) and its derivative, 2'-benzoyloxycinnamaldehyde, have recently been suggested as promising therapeutic candidates for cancer treatment. ...
Shen Jie - - 2013
This study investigated the impact of incretin on early-phase insulin secretion and glucose excursion. The normal glucose tolerance (NGT), impaired glucose tolerance (IGT), and type 2 diabetes mellitus (T2DM) groups included 16, 8, and 19 subjects, respectively. Subjects underwent continuous glucose monitoring for 3 days, followed by an oral glucose tolerance ...
Mahdavi Fard Ali - - 2013
A 19-year-old man presented with a mass in his right eye that had been present since birth but had gradually increased in size. The mass caused vision defects, mild discomfort on blinking, and the intermittent sensation of the presence of a foreign body.
Porter Michelle M - - 2013
To the Editor: Redelmeier et al. (Sept. 27 issue)(1) report the association between physicians' warnings to unfit drivers and a significant increase in patients' depression, as measured by the rate of emergency department visits for depression. Driving cessation has been correlated with increased depressive symptoms(2) and social isolation(3) and a ...
Azab Basem - - 2013
The aim of our study was to assess the predictive value of platelet/lymphocyte ratio (PLR) and neutrophil/lymphocyte ratio (NLR) in terms of survival in breast cancer patients. This is an observational study of 437 breast cancer patients treated between January 2004 and December 2006. Survival status was obtained from our ...
Laventie Benoît-Joseph - - 2013
Panton-Valentine leukocidin (PVL) and other S. aureus β-stranded pore-forming toxins are important virulence factors involved in various but often necrotizing pathologies. This study characterized leukotoxin inhibition by selected para-sulfonato-calix[n]arenes (SCn): SC4, SC6 and SC8. These chemicals have no toxic effects on human erythrocytes or neutrophils, and some are able to ...
Oddby-Muhrbeck E - - 2013
BACKGROUND: Drug-induced nausea and vomiting, both post-operatively and following chemotherapy, is often distressing for the patients. Our clinical impression is that certain patients are not prone to but instead protected against both post-operative and chemotherapy-induced nausea and vomiting (CINV). If support for this hypothesis could be generated, it might be ...
Wariki Windy Mariane Virenia - - 2013
AIM: The study aims to determine the risk factors associated with mortality and necrotising enterocolitis (NEC) among very low birthweight infants in 95 neonatal intensive care units in the Asian Network on Maternal and Newborn Health. METHODS: This is a cross-sectional study using an international collaborative database of 17 595 very ...
Wu Victor K - - 2013
BACKGROUND: Surgery is increasingly recognized as a means to reduce the morbidity and mortality of disabling impairments in resource-limited environments. We sought to estimate the burden of surgically correctable disabling impairments and the cost-effectiveness of their treatment among children in a large refugee camp. METHODS: This is a chart review ...
Todd Nathan R - - 2013
This investigation examines typologies of congregations based on patterns of congregational political and social service activities and collaborative partners. Based on a latent class analysis of a national random sample of 2,153 congregations, results indicated four distinct types of congregations with unique patterns of political, social service, and collaborative partnerships ...
Gaware Vivek S - - 2013
ABSTRACT: Water soluble amphiphilic chitosan nanocarriers tethered with the photosensitizer meso-tetraphenylporphyrin were synthesized, in a seven step procedure, starting from 3,6-di-O-tert-butyldimethylsilyl-chitosan and 5-(p-aminophenyl)-10,15,20-triphenylporphyrin. The lipophilic photosensitizer could be introduced in a quantitative and reproducible reaction to give either 0.1 or 0.25 degree of substitution per glucosamine monomer. Fluorescence and NMR ...
Buchbender Christian - - 2013
To investigate patterns of inflammatory MRI pathologies of the fore- and midfoot in rheumatoid arthritis (RA) and early RA (ERA) and their changes under therapy. In this prospective study, MRI data of the foot of 39 RA patients (29 female, 10 male; age: 54 ± 13 years; disease duration: 35 ± 37 months; baseline DAS28: 3.0 ± 2.0; ...
Laine Loren - - 2013
Gastrointestinal bleeding accounts for more than 450,000 hospitalizations annually in the United States(1) and is a frequent indication for red-cell transfusion. Blood transfusions are given to 43% of patients hospitalized with upper gastrointestinal bleeding in the United Kingdom(2) and to 21% of patients hospitalized with lower gastrointestinal bleeding in the ...
Li Na - - 2013
As a key encoding protein gene of MRN (MRE11-RAD50-NBS1) complex, NBS1 plays a crucial role in maintaining genomic stability and preventing cell apoptosis, inflammation and tumorgenesis. Single nucleotide polymorphisms (rs2735383 and rs1805794) in NBS1 have been frequently studied in some cancers with discordant results in previous case-control studies. However, the ...
Jang Eun Sun - - 2013
PURPOSE: Transarterial chemoembolization (TACE) is highly effective and safe therapeutic modality for unresectable hepatocellular carcinoma (HCC). However, the role of TACE for infiltrative HCC has never been elucidated owing to the concern about hepatic failure and subsequent mortality after the procedure. In this study, we aimed to document whether patients ...
Ghanadian Mustafa - - 2013
Chloroform-acetone extract of the aerial parts of Euphorbia aellenii Rech. f. (Euphorbiaceae) was investigated for its diterpenoidal constituents. This led to the isolation of two new and one known cyclomyrsinol-type diterpenes 1-3. The structures were elucidated on the basis of 1D and 2D (1)H and (13)C NMR techniques, and in ...
- - 2013
To the Editor: Thigpen et al. (Aug. 2 issue)(1) report that persons who are seronegative for the human immunodeficiency virus (HIV) and who are receiving tenofovir disoproxil fumarate and emtricitabine (TDF-FTC) for preexposure prophylaxis had decreased bone mineral density at 24 months, as compared with those receiving placebo. In HIV-infected ...
Ibata Rodrigo A - - 2013
Dwarf satellite galaxies are thought to be the remnants of the population of primordial structures that coalesced to form giant galaxies like the Milky Way. It has previously been suspected that dwarf galaxies may not be isotropically distributed around our Galaxy, because several are correlated with streams of H I emission, ...
Heritage Zoë - - 2013
National healthy cities networks (NNs) were created 20 years ago to support the development of healthy cities within the WHO Europe Region. Using the concept of epistemic communities, the evolution and impact of NNs is considered, as is their future development. Healthy cities national networks are providing information, training and support ...
Friedman Joseph H - - 2013
Abstract Background: The glabellar reflex (GR) is often interpreted as a clinical measure of parkinsonism although data to support this are weak. It is one of ten items used in the Simpson Angus Scale, a popular measure of parkinsonism in psychiatric studies of neuroleptic drugs. We hypothesized that the GR ...
Cho Youngnam - - 2013
The development of a target-activatable "smart" platform with high-affinity and specificity is of great importance for a wide range of biomedical applications. Here, we attempted to develop a new enzyme-activatable graphene oxide-photosensitizer complex as a biologically tunable theranostic agent, making it promising for near-infrared (NIR) fluorescence imaging and photo-induced cancer ...
Sarkhosh Maryam - - 2013
Identifying the sources of volatile organic compounds (VOCs) is key issue to reducing ground-level ozone and PAN. A multivariate receptor model (Unmix) was used for the determination of the contributions of VOCs sources in Tehran-Iran. Concentrations of ambient C(2)-C(10) VOCs were measured continuously and online at the center of Tehran ...
Marais Ben J - - 2013
To the Editor: In their historical overview of global efforts to control tuberculosis, Keshavjee and Farmer (Sept. 6 issue)(1) argue that the prioritization of global health funding based on measurable outcomes and high-return investments contributed to the fragmentation of primary health care. We agree but acknowledge that it can be ...
Nason Gregory J - - 2013
Abstract Objective.Acute scrotal pain is a common presentation to the paediatric emergency department. Testicular torsion is one of the most common causes of acute scrotal pain. Testicular torsion is a surgical emergency requiring immediate surgical exploration to prevent permanent testicular damage or loss. The aim of this study was to ...
Chen Zhangbao - - 2013
This study investigated effects of wet and dry seasons on the bacterial community structure of the Three Gorges Reservoir by using denaturing gradient gel electrophoresis analysis of the PCR-amplified bacterial 16S rRNA gene. Bacterial diversity, as determined by the Shannon index, the Simpson's index, and the Richness, dramatically changed in ...
Bornemann Kathrin - - 2013
Beet necrotic yellow vein virus (BNYVV), vectored by Polymyxa betae, causes rhizomania in sugar beet. For disease control, the cultivation of hybrids carrying Rz1 resistance is crucial, but is compromised by resistance-breaking (RB) strains with specific mutations in the P25 protein at amino acids 67-70 (tetrad). To obtain evidence for ...
Gupte Manisha - - 2013
BACKGROUND: Cardiac dysfunction is a well-known complication of subarachnoid hemorrhage (SAH). Our objective was to determine the frequency of troponin abnormalities in SAH and determine its impact on in-hospital mortality. METHODS: With IRB approval, we retrospectively reviewed 225 consecutive SAH patients admitted to our institution from August 1, 2006 to ...
Björkman Ingeborg - - 2013
Objectives. To improve education and information for general practitioners in relation to rational antibiotic prescribing for urinary tract infection (UTI), it is important to be aware of GPs' views of resistance and how it influences their choice of UTI treatment. The aim of this study was to explore variations in ...
Ma Lan - - 2013
Here, a double-strand (ds) DNA microarray-based fluorescence assay has been deployed for studying endonuclease functionality and inhibition. The dsDNA microarrays are fabricated by hybridization of the Cy5-labeled oligonucleotides with the immobilized complementary oligonucleotide probes on the glass slide. The microarray displays significant fluorescence decrease in response to endonuclease, which is ...
Ording Muller Lil-Sofie - - 2013
BACKGROUND: Bony depressions at the wrist resembling erosions are frequently seen on MRI in healthy children. The accuracy of MRI in detecting early bony destruction is therefore questionable. We compared findings on MRI of the wrist in healthy children and those with juvenile idiopathic arthritis (JIA) to investigate markers for ...
Leng Siyang - - 2013
A 44-year-old man presented to the emergency department with chest pain that had started 1 hour earlier and had awakened him from sleep. The pain was severe, substernal, burning, radiating to the left arm, and accompanied by nausea and vomiting.
van den Berg G - - 2013
BACKGROUND: Body mass index (BMI) does not make a distinction between fat mass and lean mass. In children, high fat mass appears to be associated with low maternal education, as well as low lean mass because maternal education is associated with physical activity. Therefore, BMI might underestimate true obesity in ...
Cheng Li-Kun - - 2013
Optimum production of L-tryptophan by Escherichia coli depends on pH. Here, we established conditions for optimizing the production of L-tryptophan. The optimum pH range was 6.5-7.2, and pH was controlled using a three-stage strategy [pH 6.5 (0-12 h), pH 6.8 (12-24 h), and pH 7.2 (24-38 h)]. Specifically, ammonium hydroxide was used to ...
Jiang Feng - - 2013
Size-controllable amine-functionalized graphene quantum dots (GQDs) are prepared by an eco-friendly method with graphene oxide sheets, ammonia and hydrogen peroxide as starting materials. Using a Sephadex G-25 gel column for fine separation, for the first time we obtain GQDs with either single or double layers. By atomic force microscopy characterization, ...
Motamedi Mahmood - - 2013
The aim of the current study was to evaluate for the first time the hippocampal changes in patients with pure sleep and pure waking epilepsy. A total of 35 patients with pure partial onset sleep epilepsy and 35 patients with pure partial onset waking epilepsy matched for age and sex ...
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