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Song Nianhui - - 2013
Integrating quantum dots (QDs) into modern optoelectronic devices requires an understanding of how transparent conducting substrate affects the properties of QDs, especially their excited state dynamics. Here, the exciton quenching dynamics of core/multi-shell (CdSe/CdS3MLZnCdS2MLZnS2ML) quantum dots deposited on glass, tin oxide (SnO2), and antimony (Sb) doped tin oxide (ATO) films ...
Liu Ziqi - - 2013
The human cytomegalovirus UL34 gene encodes a sequence-specific DNA binding protein that downregulates expression of the viral immune evasion gene US3. Analysis of the viral genome identified 14 potential UL34 binding sites. Using mobility shift experiments, UL34 bound to all predicted sites that were assayed (7 of 14). Furthermore, the ...
Siddiqui Athar H AH Department of Biochemistry and Molecular Biology, University of Texas-Houston Medical School, Houston, TX 77030, - - 2013
Preeclampsia (PE) is a life-threatening hypertensive disorder during pregnancy associated with decreased circulating aldosterone levels. However, the molecular mechanisms underlying aldosterone reduction in PE remain unidentified. Here we demonstrate that reduced circulating aldosterone levels in preeclamptic women are associated with the presence of angiotensin II type 1 receptor agonistic autoantibody ...
Bhat Jahangeer A - - 2013
ABSTRACT: BACKGROUND: Himalayan forests are the most important source of medicinal plants and other useful species for the local people. Kedarnath Wildlife Sanctuary (KWLS) is situated in the interior part of the Himalayan region. The presented study was carried in Madhmeshwar area of KWLS for the ecological status of plant ...
Fwu Chyng-Wen - - 2013
The occurrence of urolithiasis in the United States has increased; however, information on long-term trends, including recurrence rates, is lacking. Here we describe national trends in rates of emergency department visits, use of imaging, and drug treatment, primarily using the National Hospital Ambulatory Medical Care Survey to describe trends and ...
Baetz Nicholas W NW Section of Surgical Sciences and Epithelial Biology Center, Vanderbilt University School of Medicine, Nashville, TN 37232, - - 2013
The Rab11-family interacting proteins (Rab11-FIPs) facilitate Rab11-dependent vesicle recycling. We hypothesized that Rab11-FIPs define discrete subdomains and carry out temporally distinct roles within the recycling system. We used live-cell deconvolution microscopy of HeLa cells expressing chimeric fluorescent Rab11-FIPs to examine Rab11-FIP localization, transferrin passage through Rab11-FIP-containing compartments, and overlap among ...
Duke Felicia D - - 2013
A formalin-fixed left, blue eye, from a 9-year-old, spayed female beagle dog was submitted to the Comparative Ocular Pathology Laboratory of Wisconsin (COPLOW) for light microscopic evaluation. The history included glaucoma and an abnormal appearance for 6 months and then the development of a uveal mass. The histologic diagnosis was a ...
Pietilä Maija K - - 2013
Extremophilic archaea, both hyperthermophiles and halophiles, dominate in habitats where rather harsh conditions are encountered. Like all other organisms, archaeal cells are susceptible to viral infections, and to date, about 100 archaeal viruses have been described. Among them, there are extraordinary virion morphologies as well as the common head-tailed viruses. ...
Suzuki Hiroharu - - 2013
Hydrogen abstraction in the spotlight: UV irradiation (365 nm) of dinuclear ruthenium tetrahydride, [(Cp*Ru)(μ-H)(4) (RuCp*)] (Cp*=η(5) -C(5) Me(5) ), in a 2-alkanone, such as acetone or 2-butanone, resulted in the formation of dinuclear oxatrimethylenemethane complexes, [(Cp*Ru)(μ-η(3) :η(1) -CH(2) COCHR)(μ-H)(2) (RuCp*)] (R=H and CH(3) ), through hydrogen abstraction from the α ...
Turnipseed Sherri B - - 2013
The articles in this special issue of JAFC were originally presented at the 49th annual Florida Pesticide Residue Workshop (FPRW). The FPRW is an annual meeting for scientists specializing in trace level analysis of pesticides, veterinary drug residues, and other chemicals contaminants in food, animal feed, and environmental samples.
Chirinos Julio A - - 2013
Experimental studies implicate late systolic load as a determinant of impaired left-ventricular relaxation. We aimed to assess the relationship between the myocardial loading sequence and left-ventricular contraction and relaxation. Time-resolved central pressure and time-resolved left-ventricular geometry were measured with carotid tonometry and speckle-tracking echocardiography, respectively, for computation of time-resolved ejection-phase ...
Dangla Rémi - - 2013
The miniaturization of droplet manipulation methods has led to drops being proposed as microreactors in many applications of biology and chemistry. In parallel, microfluidic methods have been applied to generate monodisperse emulsions for applications in the pharmaceuticals, cosmetics, and food industries. To date, microfluidic droplet production has been dominated by ...
Guillo Pascal - - 2013
Tantalum polyhedral oligosilsesquioxane (POSS) complexes have been synthesised and characterized. X-ray structures of these complexes revealed that the coordination number of the tantalum center greatly affects the cube-like silsesquioxane framework.
Schonfeld Sara J SJ Department of Health and Human Services, National Institutes of Health, National Cancer Institute, Bethesda, MD, - - 2013
Although ovarian cancer incidence rates have declined in the United States, less is known of ovarian cancer trends among survivors of breast cancer. Therefore, we examined second primary ovarian cancers after first primary breast cancer. Data were obtained from the Surveillance, Epidemiology, and End Results program (1973 to 2008). Standardized ...
Warner Adam - - 2013
We have identified cpna-1 (F31D5.3) as a novel essential muscle gene in the nematode C. elegans. Antibodies specific to CPNA-1, as well as a YFP translational fusion, are localized to integrin attachment sites (M-lines and dense bodies) in the body-wall muscle of C. elegans. CPNA-1 contains an N-terminal predicted transmembrane ...
Saban Daniel R DR Department of Ophthalmology, Duke University School of Medicine, Durham, NC 27710, USA. - - 2013
The prevalence of allergy is rising globally at a very significant rate, which is currently at 20-40% of individuals in westernized nations. In the eye, allergic conditions can take on the acute form such as in seasonal and perennial allergic conjunctivitis, or a more severe and debilitating chronic form such ...
Katayama Keisho - - 2013
The purpose of the present study was to clarify the influence of inspiratory resistive breathing during exercise under hypoxic condition on muscle sympathetic nerve activity (MSNA) and blood pressure (BP). Six healthy males completed this study. The subjects performed a submaximal exercise test using a cycle ergometer in a semi-recumbent ...
Kreepala C - - 2013
We hypothesized that measurement of previously defined acute kidney injury-induced transcripts at the time of implantation would add a new dimension to existing methods based on donor factors, histology and recipient factors. We analyzed microarray results from implantation biopsies taken after reperfusion from 70 kidneys from 53 deceased donors. We ...
Kumar Sujit - - 2013
The evidence in favor of early surgical treatment of anterior cruciate ligament (ACL) injuries in children is increasing. However, the controversy regarding the safety of such a procedure in young athletes with wide open physes remains unresolved. We reviewed prospectively collected outcome data on consecutive patients who had undergone transphyseal ...
Bruun Nielsen Mette Marie - - 2013
Imaging ellipsometry (IE) has been applied to generate laterally resolved thickness maps of spincoated membranes in both the dry and fully hydrated state. Spincoating offers a convenient preparation method for stacked supported membranes and in-depth thickness maps for such films can be measured by IE, thereby going beyond topography measurements ...
Verma Pooja P National Institute of Plant Genome Research, Aruna Asaf Ali Marg, New Delhi 110067, - - 2013
PROTEIN l-ISOASPARTYL METHYLTRANSFERASE (PIMT) is a widely distributed protein-repairing enzyme that catalyzes the conversion of abnormal l-isoaspartyl residues in spontaneously damaged proteins to normal aspartyl residues. This enzyme is encoded by two divergent genes (PIMT1 and PIMT2) in plants, unlike many other organisms. While the biological role of PIMT1 has ...
Miko Benjamin A BA Division of Infectious Diseases, Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, New York, USA. - - 2013
While much is known about the geographic distribution of different clonal types of methicillin-resistant Staphylococcus aureus (MRSA), few studies have assessed the molecular epidemiology of methicillin-susceptible S. aureus (MSSA), despite its continued clinical importance. In each U.S. Census region, reference laboratories collected successive MSSA isolates from patients with invasive or ...
Wrobel Lidia - - 2013
The mitochondrial intermembrane space assembly (MIA) pathway is generally considered to be dedicated to the redox-dependent import and biogenesis of proteins localized to the intermembrane space of mitochondria. The oxidoreductase Mia40 is a central component of the pathway responsible for the transfer of disulfide bonds to intermembrane space precursor proteins ...
Xu X-M - - 2013
A qualitative and quantitative determination method for chloropropanols in soy sauce was developed by GC-MS/MS with coupled column separation without derivatisation. The target compounds were 1,3-dichloropropan-2-ol (1,3-DCP), 2,3-dichloropropan-1-ol (2,3-DCP), 3-monochloropropane-1,2-diol (3-MCPD) and 2-monochloropropane-1,3-diol (2-MCPD). 3-MCPD-d(5) was used as an isotope internal standard for MCPDs and 1,3-DCP-d(5) for DCPs. After spiking ...
Lu Xiaonan - - 2013
Conformational changes in the glycoproteins of enveloped viruses are critical for membrane fusion, which enables viral entry into cells and the pathological cell-cell fusion (syncytia) associated with some viral infections. However, technological capabilities for identifying viral glycoproteins and their conformational changes on actual enveloped virus surfaces are generally scarce, challenging, ...
Gros Robert - - 2013
We have previously demonstrated effects of aldosterone on cell growth and on contractility in vascular smooth muscle cells. We showed these effects could occur via the classic mineralocorticoid receptor (MR) as well the G protein coupled estrogen receptor (GPER). However, the mechanisms underlying aldosterone's endothelial-dependent actions are unknown. Further, the ...
Laffer Cheryl L CL Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232-6602, USA. - - 2013
We studied the characteristics of insulin resistance in 19 normotensive and 25 hypertensive subjects who underwent an acute protocol for determination of salt-sensitivity of blood pressure. Hypertensive subjects were older and more obese, with higher creatinine, lipids, and aldosterone than normotensive volunteers. They also had higher glucose and insulin levels ...
Sasaki Kosei - - 2013
Although electrical coupling is present in many microcircuits, the extent to which it will determine neuronal firing patterns and network activity remains poorly understood. This is particularly true when the coupling is present in a population of heterogeneous, or intrinsically distinct, circuit elements. We examine this question in the Aplysia ...
Jimura Koji - - 2013
A characteristic marker of impulsive decision making is the discounting of delayed rewards, demonstrated via choice preferences and choice-related brain activity. However, delay discounting may also arise from how subjective reward value is dynamically represented in the brain when anticipating an upcoming chosen reward. In the current study, brain activity ...
Basler Tina - - 2013
Mycobacterium avium ssp. paratuberculosis (MAP) causes Johne's disease, a chronic, granulomatous enteritis of ruminants. Dendritic cells (DC) of the gut are ideally placed to combat invading mycobacteria; however, little is known about their interaction with MAP. Here, we investigated the interaction of MAP and the closely related M. avium ssp. ...
Willeit Peter P Department of Neurology, Medical University Innsbruck, - - 2013
MicroRNA (miRNA) biomarkers are attracting considerable interest. Effects of medication, however, have not been investigated thus far. To analyze changes in plasma miRNAs in response to antiplatelet therapy. Profiling for 377 miRNAs was performed in platelets, platelet microparticles, platelet-rich plasma, platelet-poor plasma, and serum. Platelet-rich plasma showed markedly higher levels ...
Karasoy Deniz - - 2013
AIMS: Trends in patient selection and pharmacotherapy before radiofrequency ablation (RFA) of atrial fibrillation are not well studied. We examined temporal trends in RFA utilization on a nationwide scale in Denmark.METHODS AND RESULTS: Using the cross-linkage of nationwide registers, 3302 atrial fibrillation patients treated with 'first-ever' RFA between 2000 and ...
Thulasi Praneetha P Department of Ophthalmology, Emory University School of Medicine, Atlanta, GA, - - 2013
Determine the frequency of and the predictive factors for abnormal ocular fundus findings among emergency department (ED) headache patients. Cross-sectional study of prospectively enrolled adult patients presenting to our ED with a chief complaint of headache. Ocular fundus photographs were obtained using a nonmydriatic fundus camera that does not require ...
Chen Cheng-Yen - - 2013
Macrolide treatment failure in syphilis patients is associated with a single point mutation (either A2058G or A2059G) in both copies of the 23S rRNA gene in Treponema pallidum strains. The conventional method for the detection of both point mutations uses nested PCR combined with restriction enzyme digestions, which is laborious ...
Schyllander Jan - - 2013
Aims: The goal of this research project was to explore circumstances surrounding each drowning death occurring to children and adolescents ages 0-17 in Sweden during the years 1998-2007. Methods: Records from the National Board of Forensic Medicine (NBFM) and other sources were analysed. We collected information on children's personal characteristics ...
Ryan Miriam F MF Institute of Food and Health, University College Dublin Belfield, Dublin, Ireland. - - 2013
The response to dietary fat plays a key role in metabolic health. Although this can vary widely between individuals, variation within an individual and the associated contribution of phenotypic and genotypic factors to this variation are less defined. The objectives were to quantify within-person variation in triacylglycerol response by means ...
Hamdani Nazha - - 2013
Rationale: Myocardial diastolic stiffness and cardiomyocyte passive force (F(passive)) depend in part on titin isoform composition and phosphorylation. Ca(2+)/calmodulin-dependent protein kinase-II (CaMKII) phosphorylates ion channels, Ca2(2+)-handling proteins and chromatin-modifying enzymes in the heart, but has not been known to target titin. Objective: To elucidate whether CaMKII phosphorylates titin and modulates ...
Karasoy Deniz - - 2013
AIMS: Obesity has been associated with increased risk of atrial fibrillation (AF), but whether this risk is also prevalent in younger individuals is unknown. We therefore investigated the risk of AF in relation to body mass index (BMI) among young fertile women.METHODS AND RESULTS: By cross-linkage of nationwide registers of ...
Avidor Boaz - - 2013
Detection of low-abundance drug resistance mutations (DRMs) of HIV-1 is an evolving approach in clinical practice. Ultradeep pyrosequencing has shown to be effective in detecting such mutations. The lack of a standardized commercially based assay limits the wide use of this method in clinical settings. 454 Life Sciences (Roche) is ...
Catalina-Romero C - - 2013
AIMS: To investigate whether there is an association between job stress, lipid profile and dyslipidemia diagnosis. METHODS: This study used a questionnaire to evaluate job stress and lifestyle variables in 91,593 workers undergoing periodic checkups. Serum lipid levels were measured in all cases. RESULTS: The prevalence of job stress was ...
Gruffydd-Jones Kevin - - 2013
BACKGROUND: One of the aims of the COPD Assessment Test (CAT) is to aid communication between the physician and patient about the burden of chronic obstructive pulmonary disease (COPD) on the patient's life. AIMS: To investigate the impact of the CAT on the quality of primary care consultations in COPD ...
García-Yagüe Ángel Juan ÁJ Centro de Investigación Biomédica en Red Sobre Enfermedades Neurodegenerativas (CIBERNED), Madrid, - - 2013
Orphan receptor Nurr1 participates in the acquisition and maintenance of the dopaminergic cell phenotype, modulation of inflammation, and cytoprotection, but little is known about its regulation. In this study, we report that Nurr1 contains a bipartite nuclear localization signal (NLS) within its DNA binding domain and two leucine-rich nuclear export ...
Cometto Fernando Pablo - - 2013
High-resolution photoemission spectroscopy is used to characterize adlayers of ethane-, hexane- and nonane-dithiol molecules grown on Au(111) surfaces by the immersion method. The effect of using a reducing agent during and after the immersion to inhibit or eliminate S-S bonds is investigated. Our results demonstrate that immersion 24 h in ...
Calu Donna J DJ Intramural Research Program, National Institutes of Health/National Institute on Drug Abuse, Baltimore, Maryland 21224, USA. - - 2013
Relapse to maladaptive eating habits during dieting is often provoked by stress. Recently, we identified a role of dorsal medial prefrontal cortex (mPFC) neurons in stress-induced reinstatement of palatable food seeking in male rats. It is unknown whether endogenous neural activity in dorsal mPFC drives stress-induced reinstatement in female rats. ...
Satterly Thomas - - 2013
Four major approaches to total knee arthroplasty (TKA) exist: standard parapatellar, subvastus, midvastus, and mini-parapatellar. Research has shown that there may be some benefit to patients when minimally invasive approaches are employed. However, research has not shown whether the minimally invasive approaches are beneficial for restoring patients' gait when compared ...
Sablok Gaurav - - 2013
Microsatellites or simple sequence repeats (SSRs) are repetitive stretches of nucleotides (A, T, G, C) that are distributed either as single base pair stretches or as a combination of two- to six-nucleotides units that are non-randomly distributed within coding and in non-coding regions of the genome. ChloroMitoSSRDB is a complete ...
de Raaf Pleun J PJ Department of Medical Oncology, Daniel den Hoed Cancer Center, University Medical Center Rotterdam, Rotterdam, The Netherlands. - - 2013
Several guidelines on the treatment of cancer-related fatigue recommend optimizing treatment of accompanying symptoms. However, evidence for this recommendation from randomized clinical trials is lacking. We investigated whether monitoring and protocolized treatment of physical symptoms alleviates fatigue. In all, 152 fatigued patients with advanced cancer were randomly assigned to protocolized ...
Fu Yu - - 2013
A new type of thiacalix[4]arene-based chemosensor and containing amino groups as a binding site and 7-nitrobenzo-2-oxa-1,3-diazole (NBD) as a chromophore have been synthesized and characterized by single crystal X-ray diffraction and by NMR spectroscopic methods. Each receptor acted as a strong colorimetric and fluorometric sensor for silver ions and exhibited ...
Glenn Nicole M - - 2013
Scholars have problematized popular culture and media (re)presentations of obesity/overweight. However, few have considered the ways bariatric surgery, a rapidly growing treatment for morbid obesity, fits within the discussion. In this article, we explore news media (re)presentations of bariatric surgery using an eclectic approach to critical discourse analysis. Our findings ...
Yin Tsung-I - - 2013
Cantilever sensors have been extensively explored as a promising technique for real-time and label-free analyses in biological systems. A major sensing principle utilized by state-of-the-art cantilever sensors is based on analyte-induced surface stress changes, which result in static bending of a cantilever. The sensor performance, however, suffers from the intrinsically ...
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