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Results 501 - 550 of 3298
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Zhao Chuanqi - - 2013
G-quadruplex DNA is highly polymorphic. Its conformation transition is involved in a series of important life events. These controllable diverse structures also make G-quadruplex DNA a promising candidate as catalyst, biosensor, and DNA-based architecture. So far, G-quadruplex DNA-based applications are restricted done in aqueous media. Since many chemical reactions and ...
Schmidt Sebastian - - 2013
A nonanuclear {Fe(6)Dy(3)} coordination cluster displaying SMM behaviour in which an unprecedented chemical transformation provides structural information for the existence of 1,1,2,2-tetrahydroxyethane is reported.
Hinfray Nathalie - - 2013
Estrogens can affect expression of genes encoding steroidogenic enzymes in fish gonads. However little information is available on their effects at the protein level. In this context, we first analyzed the expression of key steroidogenic enzyme genes and proteins in zebrafish testis, paying attention also to other cell types than ...
Jonker Jacqueline T - - 2013
BACKGROUND: Angiopoietin-like protein 4 (ANGPTL4) has been identified as an inhibitor of lipoprotein lipase. Preliminary data suggest that plasma nonesterified fatty acids (NEFAs) raise plasma ANGPTL4 concentrations in humans. OBJECTIVE: The objective was to assess plasma ANGPTL4 concentrations after various nutritional interventions that increase NEFA concentrations in healthy subjects and ...
Lange Daniela - - 2013
Objective : The purpose was to examine whether a 1-h intervention would help increase fruit consumption in motivated individuals and to study the role of self-regulatory mechanisms in the behaviour change process, with a particular focus on dietary planning and action control. Methods : A randomised controlled trial compared a ...
Al-Mashhadi Rozh H - - 2013
Lack of animal models with human-like size and pathology hampers translational research in atherosclerosis. Mouse models are missing central features of human atherosclerosis and are too small for intravascular procedures and imaging. Modeling the disease in minipigs may overcome these limitations, but it has proven difficult to induce rapid atherosclerosis ...
Casassus Simon - - 2013
The formation of gaseous giant planets is thought to occur in the first few million years after stellar birth. Models predict that the process produces a deep gap in the dust component (shallower in the gas). Infrared observations of the disk around the young star HD 142527 (at a distance of ...
Philips Jo - - 2013
Microbial dechlorination of trichloroethene (TCE) is inhibited at elevated TCE concentrations. A batch experiment and modeling analysis were performed to examine whether this self-inhibition is related to an enhanced cell decay or a reduced dechlorination activity at increasing TCE concentrations. The batch experiment combined four different initial TCE concentrations (1.4 ...
Heo Seongkum - - 2013
BackgroundPatients with heart failure (HF) have poor health-related quality of life (HRQOL). The vast majority of patients have physical symptoms, and about 30-40% have depressive symptoms. The combined effects of physical and depressive symptoms on HRQOL have not been examined fully in HF.PurposesTo examine the combined effects of physical and ...
Martin L - - 2013
The main objective of this work was to establish a mathematical function that correlates pesticide residue levels in apple juice with the levels of the pesticides applied on the raw fruit, taking into account some of their physicochemical properties such as water solubility, the octanol/water partition coefficient, the organic carbon ...
Qi Yiping - - 2013
Improved methods for engineering sequence-specific nucleases, including zinc finger nucleases (ZFNs) and TAL effector nucleases (TALENs), have made it possible to precisely modify plant genomes. However, the success of genome modification is largely dependent on the intrinsic activity of the engineered nucleases. In this study, we sought to enhance ZFN-mediated ...
Carrara Davide - - 2013
INTRODUCTION: Vitamin D plasma levels are negatively associated with blood pressure and cardiovascular mortality, and vitamin D supplementation reduces cardiovascular events. Renin-angiotensin system (RAS) suppression may be one of the mechanisms involved. However, there are no interventional prospective studies demonstrating a reduction in circulating RAS components after vitamin D treatment. ...
Frisch Adam - - 2013
Abstract Background. The presence of delirium in elderly patients is common and has been identified as an independent marker for increased mortality and hospital-acquired complications, yet it is poorly recognized by health care providers. Early recognition of delirium in the prehospital setting has the potential to improve outcomes, but is ...
Shin Dong Ho - - 2013
Background: Subclinical hypothyroidism (SH) is not a rare condition in females, the elderly, or patients with chronic kidney disease (CKD). Even though previous studies have demonstrated that thyroid hormone replacement therapy (THRT) improved cardiac function and dyslipidemia in patients with subclinical hypothyroidism, it remains unclear as to whether THRT can ...
Ludvigsson Jonas - - 2013
Background and objective: In earlier studies based on selected populations, the relative risk for thyroid cancer in celiac disease has varied between 0.6 and 22.5. We aimed to test this relationship in a population-based setting. Methods: We collected small intestinal biopsy report data performed in 1969-2008 from all 28 Swedish ...
Evelein Annemieke M V - - 2013
Background:Although early life growth pattern is associated with cardiovascular disease later in life, it is unknown whether vascular changes associated with excess early weight gain already occur in early childhood.Methods:In the Wheezing-Illnesses-Study-Leidsche-Rijn (WHISTLER) birth cohort, weight and height from birth to 3 months of age were used to calculate Z-scores ...
Wang Bin - - 2013
Silicon has been touted as one of the most promising anode materials for next generation lithium ion batteries. Yet, how to build energetic silicon-based electrode architectures by addressing the structural and interfacial stability issues facing silicon anodes still remains a big challenge. Here, we develop a novel kind of self-supporting ...
Polman Albert - - 2013
Silica-gold core-shell nanoparticles that are immersed in water act as efficient nanoscale generators of steam when illuminated with sunlight. In their paper in this issue of ACS Nano, Halas, Nordlander, and co-workers demonstrate this intriguing phenomenon that results from the nucleation of steam at the surface of individual nanoparticles that ...
Siston Robert A - - 2013
Articular cartilage defects of the knee are commonly encountered during arthroscopic examination and are believed to be a precursor to osteoarthritis. While a variety of surgical treatments exist, the defect size, specifically the cross-sectional area, has historically been used as a critical element in choosing one procedure over another. The ...
Biela Adam - - 2013
The hydrophobic effect is associated with the successive replacement of water molecules in the binding site of a protein by hydrophobic groups of the ligand. Although the hydrophobic effect is assumed to be entropy-driven, large changes in enthalpy and entropy are observed with the model system thermolysin. Structural changes in ...
de Miera Cristina Sáenz - - 2013
At temperate latitudes many mammals and birds show internally timed, long-term changes in seasonal physiology, synchronised to the seasons by changing day length (photoperiod). Photoperiodic control of thyroid hormone levels in the hypothalamus dictates the timing. This is effected through reciprocal regulation of thyroid hormone deiodinase gene expression. The local ...
Langer Jens - - 2013
The transfer of the anionic Ph(2)P(BH(3))-CH-P(BH(3))Ph(2) ligand from potassium to barium results in the subsequent formation of a tetranuclear barium cluster which contains the hitherto unknown isomeric form Ph(2)P-CH(BH(3))-P(BH(3))Ph(2) of the ligand.
Andrysiak-Mamos El Bieta - - 2013
ABSTRACT: The article presents a case of 57-year-old woman with the infiltration of rare small lymphocytic B cell lymphoma in the thyroid gland. Initially, the patient was followed-up due to chronic lymphocytic B-cell leukemia diagnosed on the basis of histopathological examination of cervical lymph node. Eight months later, general symptoms ...
García-Río Luis - - 2013
The work presented herein constitutes a reply to the comments raised by Iglesias et al. on the mechanistic nature of acetylacetone nitrosation. Their sources of experimental error as well as several inconsistencies and critical factors neglected by these authors are discussed. Likewise, the additional evidence provided in this argumentation supports ...
Thong J F - - 2013
Aim: To compare narrow-band images of nasopharyngeal carcinoma with those of normal adenoidal tissue. Method: Patients with a nasopharyngeal mass were evaluated using both conventional white light and narrow-band light. Biopsies were performed and Epstein-Barr viral serology was tested for all patients. Results: Thirty consecutive patients were recruited. Twenty-one patients ...
Krobath Heinrich - - 2013
We assessed the interplay of native topology and non-native interactions on surface-tethered protein folding via extensive Monte Carlo simulations of a simple lattice model. In particular, we investigated the thermodynamics and kinetics of protein-like sequences enclosing different amounts of non-native interactions to protein energetics, and which were designed to fold ...
Beurskens Leonardus W J E - - 2013
BACKGROUND: Vitamin A has been related to the etiology of congenital diaphragmatic hernia (CDH). We performed a case-control study to investigate whether maternal dietary vitamin A intake is related to CDH in the offspring. METHODS: Thirty-one pregnancies diagnosed with CDH and 46 control pregnancies were included during the study. After ...
Laikre Linda - - 2013
The wolf (Canis lupus) is classified as endangered in Sweden by the Swedish Species Information Centre, which is the official authority for threat classification. The present population, which was founded in the early 1980s, descends from 5 individuals. It is isolated and highly inbred, and on average individuals are more ...
Seeherman Howard J - - 2013
Osteoporosis results in a decrease in bone density, bone quality, and strength throughout the skeleton. Despite systemic therapies, the morbidity and mortality that are associated with hip fractures remain a major consequence of osteoporosis. We used fourteen chronic ovariectomized female cynomolgus monkeys in this study. Six animals received an intraosseous ...
Brewer T D - - 2013
Coral reef fisheries are crucial to the livelihoods of tens of millions of people; yet, widespread habitat degradation and unsustainable fishing are causing severe depletion of stocks of reef fish. Understanding how social and economic factors, such as human population density, access to external markets, and modernization interact with fishing ...
Orozco Helena - - 2013
ABSTRACT: BACKGROUND: Yeast viability and vitality are essential for different industrial processes where the yeast Saccharomyces cerevisiae is used as a biotechnological tool. Therefore, the decline of yeast biological functions during aging may compromise their successful biotechnological use. Life span is controlled by a variety of molecular mechanisms, many of ...
Smyth Wendy - - 2013
ABSTRACT: BACKGROUND: Continued aging of the population is expected to be accompanied by substantial increases in the number of people with dementia and in the number of health care staff required to care for them. Adequate knowledge about dementia among health care staff is important to the quality of care ...
Pogue Janice M - - 2013
BACKGROUND: Central statistical monitoring in multicenter trials could allow trialists to identify centers with problematic data or conduct and intervene while the trial is still ongoing. Currently, there are few published models that can be used for this purpose. PURPOSE: To develop and validate a series of risk scores to ...
Wang Su - - 2013
Background: Whether the hematocrit is implicated in the pathogenesis of slow coronary flow (SCF) is not known. Methods: To evaluate the correlation between the hematocrit and SCF, we studied 367 patients with angiographically near-normal coronary arteries. They were divided into four quartiles based on the hematocrit. The corrected thrombolysis in ...
Garcia T S - - 2013
Diabetes affects approximately 4% of world's population and metabolic syndrome has been directly related to obesity. There is a class of nuclear receptors, peroxisome proliferator-activated receptors (PPARs), which controls the metabolism of carbohydrates and lipids. It has been considered an attractive target to treat diabetes and metabolic syndrome. Accordingly, the ...
Qu Fei - - 2013
Silver nanoclusters capped by hyperbranched polyethyleneimine (PEI) have been developed as a highly sensitive fluorescent and colorimetric pH sensor. The probe responds rapidly to pH fluctuations and has such absorption characteristics that the color changes from the colorless or a nearly colorless state to a colored state with increasing acidity, ...
Finne Emily - - 2013
ABSTRACT: BACKGROUND: Health-related quality of life (HRQoL) was found to improve in participants of weight management interventions. However, information on moderately overweight youth as well as on maintaining HRQoL improvements following treatment is sparse. We studied the HRQoL of 74 overweight, but not obese participants (32.4% male, mean age = ...
Thirsk Lorraine M - - 2013
Nurses have a key role to play in therapeutic interventions for bereaved and grieving families. In this article, hermeneutic inquiry is used to uncover what families found helpful or useful with respect to therapeutic conversations with advanced practice registered nurses. The findings show that nursing expertise is important in family ...
Muzerolle James - - 2013
Periodic increases in luminosity arising from variable accretion rates have been predicted for some pre-main-sequence close binary stars as they grow from circumbinary disks. The phenomenon is known as pulsed accretion and can affect the orbital evolution and mass distribution of young binaries, as well as the potential for planet ...
Sun Di - - 2013
A novel octanuclear Ag(I)(6)-Zn(II)(2) heterometallic aggregate, (NH(4))(2){[Zn(2)(phen)(2)(H(2)O)(4)][Ag(6)(mna)(6)]}·2H(2)O·2CH(3)CH(2)OH (, H(2)mna = 2-mercaptonicotinic acid, phen = 1,10-phenanthroline), was stepwisely obtained based on a hexanuclear silver(i) metalloligand using a liquid-liquid diffusion method. It is an exceedingly rare example that exhibits interesting temperature dependent photoluminescence behaviors, including gradual changes in energy and intensity upon ...
Lee Wan Ling - - 2013
Background:Poor adherence is a significant nursing and public health concern because it affects patients' quality of life. It compounds the disease burden of the growing coronary heart disease population. Promoting optimal patient adherence to cardiac-health enhancing recommendations by healthcare providers can reduce mortality and morbidity risk after acute coronary syndrome ...
Liu F - - 2013
Exposure to one metal might have significant effects on the bioaccumulation of other metals. In the present study, we have examined the possible effects of Zn exposure on the bioaccumulation of Cd and Cu in three populations of oysters Crassostrea hongkongensis. We found that Zn exposure significantly enhanced the tissue ...
Yu Tung-Yang - - 2013
ABSTRACT: BACKGROUND: Most tendon pathology is associated with degeneration, which is thought to involve cyclic loading and cumulative age-related changes in tissue architecture. However, the association between aging and degeneration of the extracellular matrix (ECM) in tendons has not been investigated extensively. METHODS: We examined tenocytes from Achilles tendons taken ...
Hermans Michel P - - 2013
BACKGROUND: Obstructive sleep apnoea syndrome (OSAS) is a risk factor for T2DM, and promotes CV events, especially in males. The prevalence of OSAS and its association with micro- and macrovascular diseases and glycaemic control are poorly documented in T2DM females. METHODS: 305 T2DM females; OSAS diagnosed through (hetero)anamnesis, Epworth's score, ...
Juntunen Pekka - - 2013
AIM: To determine if therapeutic treatment of pigs with chlortetracycline affects the susceptibility of their Campylobacter isolates for tetracycline, ciprofloxacin and erythromycin. METHODS AND RESULTS: Minimum inhibitory concentrations (MICs) and presence of a tetracycline resistance gene tet(O) were studied in Campylobacter collected before, during and after chlortetracycline treatment. Tetracycline MICs ...
Jayasuriya Raveen L - - 2013
This two-year randomized clinical trial was performed to examine whether the geometry of the cemented femoral prosthesis affects the pattern of strain-adaptive bone remodeling in the proximal aspect of the femur after primary total hip arthroplasty. One hundred and twenty patients were randomized to receive a Charnley (composite-beam), Exeter (double-tapered), ...
Wang Chunsheng - - 2013
Nano-Sn/C composites are ideal anode materials for high energy and power density Li-ion batteries. However, because of the low melting point of Sn and the tendency of grain growth, especially during high temperature carbonization, it has been a significant challenge to create well-dispersed ultra-small Sn nano-particles within a carbon matrix. ...
Jaarsma Debbie - - 2013
Background: Since the 1970s, the Dutch have been active innovators and researchers in the medical education domain. With regards to the quantity of publications in the medical education literature, the Netherlands rank second among countries in Europe and fourth worldwide over the past years, related to the journals with highest ...
Seal Manas - - 2013
Redox active metals (Fe and Cu) and cofactors (heme) bind to Aβ peptides and react with O(2) in their reduced state leading to oxidative stress in the brain. In this study we cryogenically trap and characterize a Fe-O(2) intermediate, using resonance Raman spectroscopy, involved in reactive oxygen species formation by ...
Merikanto Ilona - - 2013
In this study, the authors analyzed whether chronotypes, sleep duration, and sleep sufficiency are associated with cardiovascular diseases and type 2 diabetes by using the National FINRISK Study 2007 data (N = 6258), being a representative sample of the population aged 25 to 74 living in five areas of Finland. Health status ...
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