Search Results
Results 451 - 500 of 3304
< 5 6 7 8 9 10 11 12 13 14 15 >
Phabphal Kanitpong K Neurology Unit, Department of Medicine, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla, - - 2013
This study sought to determine the association between BsmI polymorphism and bone mineral density, 25-hydroxyvitamin D, and parathyroid hormone levels in patients with epilepsy. We recruited ambulatory young adults with epilepsy who were taking phenytoin. Data regarding demographics, basic laboratory studies, history of clinical epilepsy, parathyroid hormone, and vitamin D ...
Adum Gilbert Baase - - 2013
There is a lack of quantitative information on the effectiveness of selective-logging practices in ameliorating effects of logging on faunal communities. We conducted a large-scale replicated field study in 3 selectively logged moist semideciduous forests in West Africa at varying times after timber extraction to assess post logging effects on ...
Knickmeyer Rebecca C - - 2013
Studies in adolescents and adults have demonstrated that polymorphisms in putative psychiatric risk genes are associated with differences in brain structure, but cannot address when in development these relationships arise. To determine if common genetic variants in disrupted-in-schizophrenia-1 (DISC1; rs821616 and rs6675281), catechol-O-methyltransferase (COMT; rs4680), neuregulin 1 (NRG1; rs35753505 and ...
Martino Francesca F Nephrology, Dialysis, and Transplantation, St. Bortolo Hospital, Vicenza, Italy. - - 2013
In the present study, we assessed expression of neutrophil gelatinase-associated lipocalin (NGAL) in peritoneal effluent (pNGAL) from peritoneal dialysis (PD) patients, and we evaluated factors that might affect its level in basal conditions. Our cross-sectional study included all 69 patients on PD at our institution. We evaluated patient history, hydration ...
Rana Tanmoy - - 2013
Arsenic is one of the most hazardous substances in the environment known to cause toxicity in multiple organs. Cell adhesion, morphological alterations, cell proliferation, terminal deoxyuridine triphosphate nick-end labeling (TUNEL) and caspase-3/CPP32 fluorometric protease assay were important biomarkers to assess apoptosis in cells. This study aimed to evaluate arsenic-induced apoptosis ...
Lin Laiyi - - 2013
Adhesive micropattern arrays permit the continuous monitoring and systematic study of the behavior of spatially confined cells of well-defined shape and size in ordered configurations. This technique has contributed to defining mechanisms that control cell polarity and cell functions, including proliferation, apoptosis, differentiation and migration in two-dimensional cell culture systems. ...
Tsang Pamela S PS . Department of Psychology, Wright State University, Dayton, OH 45434, USA. - - 2013
The research examines the structural bottleneck account and the resource account of the substantial dual-task deficits among older adults. Procedures from two common dual-task methodologies-the psychological refractory period and the relative-priority manipulation-were used to encourage maximization of the joint performance. Performance and time-sharing strategies from subjects between the ages of ...
Friederici Angela D - - 2013
Learning takes place throughout lifetime but differs in infants and adults because of the immaturity of the PFC, a brain region responsible for cognitive control. To test this hypothesis, adults were investigated in a language learning paradigm under inhibitory, cathodal transcranial direct current stimulation over PFC. The experiment included a ...
Kirkness Ewen F - - 2013
There is increasing evidence that the phenotypic effects of genomic sequence variants are best understood in terms of variant haplotypes rather than as isolated polymorphisms. Haplotype analysis is also critically important for uncovering population histories, and for the study of evolutionary genetics. Although the sequencing of individual human genomes to ...
Wang Yu-Jing - - 2013
OBJECTIVE: The angiotensinogen (AGT) gene M235T polymorphism has been reported to be associated with myocardial infarction (MI), but previous studies have been inconsistent. The present study aimed at assessing the association of M235T polymorphism in the AGT gene with MI using a meta-analysis. METHODS: We retrieved literature in Google Scholar, ...
Chen Eric Y - - 2013
Previous studies have shown that motion onset is very effective at capturing attention and is more salient than smooth motion. Here, we find that this salience ranking is present already in the firing rate of retinal ganglion cells. By stimulating the retina with a bar that appears, stays still, and ...
Zaborowski Anthony Grant - - 2013
Abstract Purpose: To report a case of cytomegalovirus (CMV) retinitis in an HIV-negative, iatrogenically immunosuppressed patient with chronic uveitis following intravitreal triamcinolone acetonide (IVTA). Design: Observational case report. Methods: A 56-year-old female with chronic idiopathic panuveitis on azathioprine received a single 4-mg IVTA injection for macular edema and presented after ...
Rulli Maria Cristina - - 2013
Societal pressure on the global land and freshwater resources is increasing as a result of the rising food demand by the growing human population, dietary changes, and the enhancement of biofuel production induced by the rising oil prices and recent changes in United States and European Union bioethanol policies. Many ...
D'Elia Riccardo V - - 2013
Inflammation is the body's first line of defense against infection or injury, responding to challenges by activating innate and adaptive responses. Microbes have evolved a diverse range of strategies to avoid triggering inflammatory responses. However, some pathogens, such as the influenza virus and the Gram-negative bacterium Francisella tularensis, do trigger ...
Perez-Lopez Araceli - - 2013
Salmonella infects and survives within B cells, but the mechanism used by the bacterium to promote its survival in these cells is unknown. In macrophages, flagellin secreted by Salmonella activates the Nod-like receptor (NLR) family CARD domain containing protein 4 (NLRC4) inflammasome, leading to the production of IL-1β and pyroptosis ...
Ryu Eun Sun - - 2013
Recent experimental and clinical studies suggest a causal role of uric acid in the development of chronic kidney disease. Most studies have focused on uric acid-induced endothelial dysfunction, oxidative stress and inflammation in the kidney. Direct effects of uric acid on tubular cells have not been studied in detail, and ...
Yang Albert C - - 2013
Bipolar disorder seasonality has been documented previously, though information on the effect of demographic and clinical variables on seasonal patterns is scant. This study examined effects of age, sex, index admission, and predominant polarity on bipolar disorder seasonality in a nationwide population. An inpatient cohort admitted to hospital exclusively for ...
Wu Guorong - - 2013
Deformable registration has been widely used in neuroscience studies for spatial normalization of brain images onto the standard space. Because of possible large anatomical differences across different individual brains, registration performance could be limited when trying to estimate a single directed deformation pathway, i.e., either from template to subject or ...
Park Yong-Hee - - 2013
BACKGROUND: This study was designed to compare the efficacy of prophylactic ramosetron and ondansetron in preventing postoperative vomiting in children who received fentanyl by patient-controlled analgesia after orthopedic surgery. METHODS: Two hundred and eighteen children, 2-15 years old, ASA physical status 1 or 2, scheduled for elective orthopedic surgeries, were randomly ...
Wong Gene W - - 2013
Over and over again: Various alkenes underwent the title reaction in the presence of rhodium/bis(diazaphospholane) complexes to give γ-chiral α,β-unsaturated carbonyl products (46-96 % yield) with high enantioselectivity (90-99 % ee). Iterative sequences of the reaction lead to stereoselective CC bond formations between achiral reactants to produce product having multiple stereocenters (see ...
Lee Anna M AM Ernest Gallo Clinic and Research Center, Department of Neurology, University of California, San Francisco, 5858 Horton Street, Suite 200, Emeryville, California 94608, - - 2013
Protein kinase M-ζ (PKM-ζ) is a constitutively active form of atypical protein kinase C that is exclusively expressed in the brain and implicated in the maintenance of long-term memory. Most studies that support a role for PKM-ζ in memory maintenance have used pharmacological PKM-ζ inhibitors such as the myristoylated zeta ...
Barlow Amanda J AJ Stowers Institute for Medical Research, 1000 E. 50th Street, Kansas City, MO 64110, USA. - - 2013
Hirschsprung disease (HSCR) is a human congenital disorder, defined by the absence of ganglia from variable lengths of the colon. These ganglia comprise the enteric nervous system (ENS) and are derived from migratory neural crest cells (NCCs). The inheritance of HSCR is complex, often non-Mendelian and characterized by variable penetrance. ...
Yildirim Adem - - 2013
A large-area superhydrophobic and omnidirectional antireflective nanostructured organically modified silica coating has been designed and prepared. The coating mimics the self-cleaning property of superhydrophobic lotus leaves and omnidirectional broad band antireflectivity of moth compound eyes, simultaneously. Water contact and sliding angles of the coating are around 160° and 10°, respectively. ...
Carneiro Ana Carolina Aguiar Vasconcelos - - 2013
Recent studies of Toxoplasma gondii isolates from animals in Brazil have revealed high genetic diversity. Many of these isolates are virulent to mice. It is speculated that these isolates may also be virulent to humans. However, there is very limited data regarding T. gondii strains from human infection. Therefore, it ...
Yang Lingling - - 2013
Trichostatin A (TSA) has been shown to prevent fibrosis in vitro and in vivo. The present study aimed at investigating the role of reactive oxygen species (ROS) scavenging by TSA on TGF-β-induced myofibroblast differentiation of corneal fibroblasts in vitro. Human immortalized corneal fibroblasts were treated with TGF-β in the presence ...
Pearce Ryan C - - 2013
Vertically aligned carbon nanofibers (VACNFs) are synthesized on Al 3003 alloy substrates by direct current plasma-enhanced chemical vapor deposition. Chemically synthesized Ni nanoparticles were used as the catalyst for growth. The Si-containing coating (SiNx) typically created when VACNFs are grown on silicon was produced by adding Si microparticles prior to ...
Hou Tingting T State Key Laboratory of Biomembrane and Membrane Biotechnology, Institute of Molecular Medicine, Peking-Tsinghua Center for Life Sciences, Peking University, Beijing 100871, - - 2013
Mitochondrial superoxide flashes reflect a quantal, bursting mode of reactive oxygen species (ROS) production that arises from stochastic, transient opening of the mitochondrial permeability transition pore (mPTP) in many types of cells and in living animals. However, the regulatory mechanisms and the exact nature of the flash-coupled mPTP remain poorly ...
Holmes Christina - - 2013
Substrate-mediated transfection is one of the key strategies for localized gene delivery. Layer-by-layer (LbL) polyelectrolyte deposition is a promising technique which enables controlled delivery of a number of biofactors, including nucleic acids. Here, we embed lipoplexes containing plasmid DNA within polyelectrolyte multilayers composed of glycol-chitosan (Glyc-CHI) and hyaluronic acid (HA) ...
Felser Claudia - - 2013
Topologically stable magnetic screw-like nanostructures called skyrmions were designed by using the concept of topology and the guidance of theory. These particles in real space are found in non-centrosymmetric compounds such as MnSi. Skyrmions might have an enormous impact in the context of future spintronics applications.
Mandal Amit - - 2013
Multiwalled carbon nanotubes (MWNTs) are functionalized covalently with ionic liquid (IL, 3-aminoethyl imidazolium bromide) which helps good dispersion of IL- functionalized MWNT (MWNT-IL) in the poly(vinylidene fluoride) (PVDF) matrix. Analysis of TEM micrographs suggests ~10 nm coating thickness of MWNTs by IL and the covalent linkage of IL with MWNT ...
Schmidt Sebastian - - 2013
A nonanuclear {Fe(6)Dy(3)} coordination cluster displaying SMM behaviour in which an unprecedented chemical transformation provides structural information for the existence of 1,1,2,2-tetrahydroxyethane is reported.
Hinfray Nathalie - - 2013
Estrogens can affect expression of genes encoding steroidogenic enzymes in fish gonads. However little information is available on their effects at the protein level. In this context, we first analyzed the expression of key steroidogenic enzyme genes and proteins in zebrafish testis, paying attention also to other cell types than ...
Gupta Sachin Kumar SK Mina and Everard Goodman Faculty of Life Sciences, and Advanced Materials and Nanotechnology Institute, Bar-Ilan University, Ramat-Gan 52900, - - 2013
Gene expression in trypanosomes is mainly regulated post-transcriptionally. Genes are transcribed as polycistronic mRNAs that are dissected by the concerted action of trans-splicing and polyadenylation. In trans-splicing, a common exon, the spliced leader, is added to all mRNAs from a small RNA. In this study, we examined by microarray analysis ...
Jonker Jacqueline T - - 2013
BACKGROUND: Angiopoietin-like protein 4 (ANGPTL4) has been identified as an inhibitor of lipoprotein lipase. Preliminary data suggest that plasma nonesterified fatty acids (NEFAs) raise plasma ANGPTL4 concentrations in humans. OBJECTIVE: The objective was to assess plasma ANGPTL4 concentrations after various nutritional interventions that increase NEFA concentrations in healthy subjects and ...
Jia Kun-Tong - - 2013
Infectious spleen and kidney necrosis virus (ISKNV) is the type species of the genus Megalocytivirus from the family Iridoviridae. ISKNV is one of the major agents that cause mortality and economic losses to the freshwater fish culture industry in Asian countries, particularly for mandarin fish (Siniperca chuatsi). In the present ...
Lange Daniela - - 2013
Objective : The purpose was to examine whether a 1-h intervention would help increase fruit consumption in motivated individuals and to study the role of self-regulatory mechanisms in the behaviour change process, with a particular focus on dietary planning and action control. Methods : A randomised controlled trial compared a ...
Lu Fuqu F Department of Medical Genetics, Alberta Children's Hospital Research Institute, University of Calgary, Calgary, Alberta T2N 4N1, - - 2013
The brain plays a central role in controlling energy, glucose, and lipid homeostasis, with specialized neurons within nuclei of the mediobasal hypothalamus, namely the arcuate (ARC) and ventromedial (VMH), tasked with proper signal integration. Exactly how the exquisite cytoarchitecture and underlying circuitry becomes established within these nuclei remains largely unknown, ...
Shushruth S - - 2013
In primary visual cortex (V1), neuronal responses to stimuli inside the receptive field (RF) are usually suppressed by stimuli in the RF surround. This suppression is orientation specific. Similarly, in human vision surround stimuli can suppress perceived contrast of a central stimulus in an orientation-dependent manner. The surround consists of ...
Carlo Anne-Sophie AS Max Delbrueck Center for Molecular Medicine, D-13125 Berlin, - - 2013
Apolipoprotein E (APOE) is the major risk factor for sporadic Alzheimer's disease. Among other functions, APOE is proposed to sequester neurotoxic amyloid-β (Aβ) peptides in the brain, delivering them to cellular catabolism via neuronal APOE receptors. Still, the receptors involved in this process remain controversial. Here, we identified the pro-neurotrophin ...
Frisch Adam - - 2013
Abstract Background. The presence of delirium in elderly patients is common and has been identified as an independent marker for increased mortality and hospital-acquired complications, yet it is poorly recognized by health care providers. Early recognition of delirium in the prehospital setting has the potential to improve outcomes, but is ...
Volk Lenora J LJ Department of Neuroscience, Howard Hughes Medical Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, - - 2013
Long-term potentiation (LTP), a well-characterized form of synaptic plasticity, has long been postulated as a cellular correlate of learning and memory. Although LTP can persist for long periods of time, the mechanisms underlying LTP maintenance, in the midst of ongoing protein turnover and synaptic activity, remain elusive. Sustained activation of ...
Vukmanovic-Stejic Milica M Division of Infection and Immunity, University College London, London W1T 4JF, United - - 2013
We investigated the relationship between varicella zoster virus (VZV)-specific memory CD4(+) T cells and CD4(+)Foxp3(+) regulatory T cells (Tregs) that accumulate after intradermal challenge with a VZV skin test Ag. VZV-specific CD4(+) T cells were identified with a MHC class II tetramer or by intracellular staining for either IFN-γ or ...
Evelein Annemieke M V - - 2013
Background:Although early life growth pattern is associated with cardiovascular disease later in life, it is unknown whether vascular changes associated with excess early weight gain already occur in early childhood.Methods:In the Wheezing-Illnesses-Study-Leidsche-Rijn (WHISTLER) birth cohort, weight and height from birth to 3 months of age were used to calculate Z-scores ...
Wang Bin - - 2013
Silicon has been touted as one of the most promising anode materials for next generation lithium ion batteries. Yet, how to build energetic silicon-based electrode architectures by addressing the structural and interfacial stability issues facing silicon anodes still remains a big challenge. Here, we develop a novel kind of self-supporting ...
Kesse-Guyot Emmanuelle - - 2013
Evidence on the association between Mediterranean diet (MedDiet) adherence and cognition is presently inconsistent. The aims of this study were to investigate the association between midlife MedDiet adherence and cognitive performance assessed 13 y later among participants in the SU.VI.MAX (Supplementation with Vitamins and Mineral Antioxidants) study and to test ...
Polman Albert - - 2013
Silica-gold core-shell nanoparticles that are immersed in water act as efficient nanoscale generators of steam when illuminated with sunlight. In their paper in this issue of ACS Nano, Halas, Nordlander, and co-workers demonstrate this intriguing phenomenon that results from the nucleation of steam at the surface of individual nanoparticles that ...
Hornborg Sara S Swedish Institute for Food and Biotechnology, Sustainable Food Production, Sweden. - - 2013
Mean trophic level (MTL) of landings and primary production required (PPR) by fisheries are increasingly used in the assessment of sustainability in fisheries. However, in their present form, MTL and PPR are prone to misinterpretation. We show that it is important to account for actual catch data, define an appropriate ...
Guzinski Marcin - - 2013
Thioamide derivatives of p-tert-butylcalix[4]arene were used as ionophores in the development of solid contact ion selective electrodes based on conducting polymer (PEDOT/PSS) which was synthesized by electrodeposition on the glassy carbon electrodes. The typical ion selective membranes with optionally two different plasticizers (DOS and NPOE) were investigated. The potentiometric selectivity ...
Strand Tor A - - 2013
BACKGROUND: Micronutrient deficiencies can affect cognitive function. Many young children in low- and middle-income countries have inadequate cobalamin (vitamin B-12) status. OBJECTIVE: The objective was to measure the association of plasma concentrations of folate, cobalamin, total homocysteine, and methylmalonic acid with cognitive performance at 2 occasions, 4 mo apart, in ...
Backfisch Benjamin - - 2013
Research in eye evolution has mostly focused on eyes residing in the head. In contrast, noncephalic light sensors are far less understood and rather regarded as evolutionary innovations. We established stable transgenesis in the annelid Platynereis, a reference species for evolutionary and developmental comparisons. EGFP controlled by cis-regulatory elements of ...
< 5 6 7 8 9 10 11 12 13 14 15 >