Search Results
Results 451 - 500 of 3299
< 5 6 7 8 9 10 11 12 13 14 15 >
Ryu Eun Sun - - 2013
Recent experimental and clinical studies suggest a causal role of uric acid in the development of chronic kidney disease. Most studies have focused on uric acid-induced endothelial dysfunction, oxidative stress and inflammation in the kidney. Direct effects of uric acid on tubular cells have not been studied in detail, and ...
Yang Albert C - - 2013
Bipolar disorder seasonality has been documented previously, though information on the effect of demographic and clinical variables on seasonal patterns is scant. This study examined effects of age, sex, index admission, and predominant polarity on bipolar disorder seasonality in a nationwide population. An inpatient cohort admitted to hospital exclusively for ...
Wu Guorong - - 2013
Deformable registration has been widely used in neuroscience studies for spatial normalization of brain images onto the standard space. Because of possible large anatomical differences across different individual brains, registration performance could be limited when trying to estimate a single directed deformation pathway, i.e., either from template to subject or ...
Park Yong-Hee - - 2013
BACKGROUND: This study was designed to compare the efficacy of prophylactic ramosetron and ondansetron in preventing postoperative vomiting in children who received fentanyl by patient-controlled analgesia after orthopedic surgery. METHODS: Two hundred and eighteen children, 2-15 years old, ASA physical status 1 or 2, scheduled for elective orthopedic surgeries, were randomly ...
Ryan Damien - - 2013
Abstract Background. Little is known about clinically important events and advanced care treatment that patients with ST-segment elevation myocardial infarction (STEMI) encounter in the prehospital setting. Objectives. We sought to determine the proportion of community patients with STEMI who experienced a clinically important event or received advanced care treatment prior ...
Wittmer Heiko U - - 2013
Apparent competition is an indirect interaction between 2 or more prey species through a shared predator, and it is increasingly recognized as a mechanism of the decline and extinction of many species. Through case studies, we evaluated the effectiveness of 4 management strategies for species affected by apparent competition: predator ...
Zeng Teng - - 2013
Prairie pothole lakes (PPLs) are naturally sulfur-enriched wetlands in the glaciated prairie region of North America. High sulfate levels and dynamic hydrogeochemistry in combination render PPLs a unique environment to explore the speciation of sedimentary sulfur (S). The goals of this research were to define and quantify the solid phase ...
Knirel Yuriy A - - 2013
Shigella flexneri is the major human pathogen causing shigellosis. O-antigens of all S. flexneri serotypes (except for serotype 6) share the →2)-α-L-Rhap(III)-(1→2)-α-L-Rhap(II)-(1→3)-α-L-Rhap(I)-(1→3)-β-D-GlcpNAc-(1→ basic O-unit, whereas differences between the serotypes are conferred by phage-encoded glucosylation and/or O-acetylation at various positions. Recently, in serotype X and 4a variants called Xv and 4av, ...
Busschaert Nathalie - - 2013
The development of small-molecule lipid-bilayer anion transporters for potential future use in channel replacement therapy for the treatment of diseases caused by dysregulation of anion transport (such as cystic fibrosis), and in treating cancer by perturbing chemical gradients within cells, thus triggering apoptosis, is an area of intense current interest. ...
Kontak Andrew C - - 2013
Cocaine-induced acute hypertension is mediated largely by increased central sympathetic nerve activity. We hypothesized that dexmedetomidine, a central sympatholytic, reverses cocaine-induced increases in sympathetic nerve activity, mean arterial pressure (MAP), and heart rate (HR) in cocaine-addicted subjects. First, we conducted a dose-finding study in 15 nontreatment-seeking cocaine-addicted subjects and 12 ...
Hamdani Nazha - - 2013
Rationale: Myocardial diastolic stiffness and cardiomyocyte passive force (F(passive)) depend in part on titin isoform composition and phosphorylation. Ca(2+)/calmodulin-dependent protein kinase-II (CaMKII) phosphorylates ion channels, Ca2(2+)-handling proteins and chromatin-modifying enzymes in the heart, but has not been known to target titin. Objective: To elucidate whether CaMKII phosphorylates titin and modulates ...
Karasoy Deniz - - 2013
AIMS: Obesity has been associated with increased risk of atrial fibrillation (AF), but whether this risk is also prevalent in younger individuals is unknown. We therefore investigated the risk of AF in relation to body mass index (BMI) among young fertile women.METHODS AND RESULTS: By cross-linkage of nationwide registers of ...
Catalina-Romero C - - 2013
AIMS: To investigate whether there is an association between job stress, lipid profile and dyslipidemia diagnosis. METHODS: This study used a questionnaire to evaluate job stress and lifestyle variables in 91,593 workers undergoing periodic checkups. Serum lipid levels were measured in all cases. RESULTS: The prevalence of job stress was ...
Gruffydd-Jones Kevin - - 2013
BACKGROUND: One of the aims of the COPD Assessment Test (CAT) is to aid communication between the physician and patient about the burden of chronic obstructive pulmonary disease (COPD) on the patient's life. AIMS: To investigate the impact of the CAT on the quality of primary care consultations in COPD ...
Cometto Fernando Pablo - - 2013
High-resolution photoemission spectroscopy is used to characterize adlayers of ethane-, hexane- and nonane-dithiol molecules grown on Au(111) surfaces by the immersion method. The effect of using a reducing agent during and after the immersion to inhibit or eliminate S-S bonds is investigated. Our results demonstrate that immersion 24 h in ...
Lomas Alexander James - - 2013
The benefits associated with polyhydroxyalkanoates (PHA) in tissue engineering include high immunotolerance, low toxicity, and biodegradability. Poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) (PHBHHx), a molecule from the PHA family of biopolymers, shares these features. In this study, the applicability of human Embryonic Stem Cells (hESCs), spontaneously differentiated hESCs (SDhESCs) and Mesenchymal Stem Cells (hMSCs) in ...
Kattipattanapong Woraya - - 2013
Objective(1) To compare the rate of surgical site infections in ear surgery between groups with and without hair removal and (2) to study factors associated with surgical site infections.Study DesignA preliminary, randomized, controlled trial.SettingUniversity hospital.Subjects and MethodsThe study was conducted in a group of 136 patients who underwent surgery for ...
Satterly Thomas - - 2013
Four major approaches to total knee arthroplasty (TKA) exist: standard parapatellar, subvastus, midvastus, and mini-parapatellar. Research has shown that there may be some benefit to patients when minimally invasive approaches are employed. However, research has not shown whether the minimally invasive approaches are beneficial for restoring patients' gait when compared ...
Sablok Gaurav - - 2013
Microsatellites or simple sequence repeats (SSRs) are repetitive stretches of nucleotides (A, T, G, C) that are distributed either as single base pair stretches or as a combination of two- to six-nucleotides units that are non-randomly distributed within coding and in non-coding regions of the genome. ChloroMitoSSRDB is a complete ...
Fu Yu - - 2013
A new type of thiacalix[4]arene-based chemosensor and containing amino groups as a binding site and 7-nitrobenzo-2-oxa-1,3-diazole (NBD) as a chromophore have been synthesized and characterized by single crystal X-ray diffraction and by NMR spectroscopic methods. Each receptor acted as a strong colorimetric and fluorometric sensor for silver ions and exhibited ...
Glenn Nicole M - - 2013
Scholars have problematized popular culture and media (re)presentations of obesity/overweight. However, few have considered the ways bariatric surgery, a rapidly growing treatment for morbid obesity, fits within the discussion. In this article, we explore news media (re)presentations of bariatric surgery using an eclectic approach to critical discourse analysis. Our findings ...
Yin Tsung-I - - 2013
Cantilever sensors have been extensively explored as a promising technique for real-time and label-free analyses in biological systems. A major sensing principle utilized by state-of-the-art cantilever sensors is based on analyte-induced surface stress changes, which result in static bending of a cantilever. The sensor performance, however, suffers from the intrinsically ...
Guerrini Luca - - 2013
Synthesis of asymmetric nanoparticles, such as gold nanorods, with tunable optical properties providing metal structures with improved SERS performance is playing a critical role in expanding the use of SERS to imaging and sensing applications. However, the synthetic methods usually require surfactants or polymers as shape-directing agents. These chemicals normally ...
Deinbeck Kristin - - 2013
ABSTRACT: Purpose: To evaluate the efficacy of radiotherapy (RT) for early-stage nodal and extranodal marginal zone lymphoma (MZL).Materials and methods: Patients with stage I (n = 22) and stage II (n = 8) MZL, who were treated with RT were reviewed. The primary tumor localisation was in the orbita (n ...
Yamashita Kei - - 2013
An assemblage of a Tb(iii) ion and two mononuclear [Zn(II)(L)] complexes as antenna chromophores (H(2)L: Schiff base ligand) afforded a luminescent single-molecule magnet. The f-f emission spectrum had partially resolved fine structure which provides detailed information on the magnetic anisotropy of the (7)F(6) ground multiplet of the Tb(iii) ion.
Franssen Nicole M G - - 2013
Rh-mediated carbene (co)polymerisation of diazomethane works best in the presence of Rh(III) catalyst precursors, the use of which leads to a significant increase in polymer yield and molecular weight. Chain termination via β-hydride elimination is severely suppressed for these species, although this process does still occur leading to unsaturated chain ...
Skogli Erik Winther - - 2013
The aim of the study was to compare executive processes with pronounced (hot) and less pronounced (cold) emotional salience in medication naïve children and adolescents with ADHD-combined (ADHD-C) and ADHD-inattentive (ADHD-I) subtypes. Thirty-six subjects with ADHD-C, 44 with ADHD-I, and 50 healthy controls between 8 and 17 years were assessed ...
Yang Guang-Sheng - - 2013
Two S-containing MOFs, interpenetrating and non-interpenetrating , were synthesized by altering solvent size. The nanoporous reveals high selective adsorption for Cu(2+) ions and has been applied as a chromatographic column for separating transition metal ions for the first time.
Kern Wolfgang - - 2013
BACKGROUND: Within the myelodysplastic/myeloproliferative neoplasm (MDS/MPN) category of the WHO (2008), only chronic myelomonocytic leukemia was so far evaluated by multiparameter flow cytometry (MFC). METHODS: To investigate the potential of MFC for MDS/MPNs, unclassifiable (MDS/MPNu), and refractory anemia associated with ring sideroblasts and marked thrombocytosis (RARS-T), we studied 91 patients ...
Karam Matthew D - - 2013
Acquisition of surgical skills through laboratory-based training and simulation is appealing to surgical training programs. The purpose of this study was to provide baseline information on the current use of surgical skills training laboratories in orthopaedic resident education and to determine the interest in expansion of these facilities and training ...
Miao Sheng - - 2013
Pyramidal neurons have a highly polarized dendritic morphology, characterized by one long apical dendrite and multiple short basal dendrites. They function as the primary excitatory cells of the mammalian prefrontal cortex and the corticospinal tract. However, the molecular mechanisms underlying the development of polarized dendrite morphology in pyramidal neurons remain ...
Dukhovny Dmitry - - 2013
Objective A previous multisite, randomized, controlled trial of peer support compared with usual care for prevention of postpartum depression demonstrated a reduction in depression symptoms at 12 weeks postbirth. Our objective was to determine the cost-effectiveness of this intervention.Study Design Prospectively planned economic evaluation alongside the clinical trial to determine the cost ...
Zhang Jing-Xian - - 2013
Seven new neolignanamides (1-7), including two pairs of cis- and trans-isomers, and a new lignanamide (8) were isolated from the EtOAc-soluble fraction of an EtOH extract of the root bark of Lycium chinense, together with 22 known phenolic compounds (9-30), four of which were obtained from the genus Lycium for ...
Suárez-Ortiz G Alejandra - - 2013
The (6'S)-configuration of brevipolides A-J (1-10), isolated from Hyptis brevipes, was established by X-ray diffraction analysis of 9 in conjunction with Mosher's ester analysis of the tetrahydro derivative 11 obtained from both geometric isomers 8 and 9 as well as by chemical correlations. The structure of the new brevipolide J ...
Wei Jerry - - 2013
Mammary transcriptome analyses across the lactation cycle, and transgenic animal studies have identified candidate genes for mammogenesis, lactogenesis and involution, however, there is a lack of information on pathways that contribute lactation performance. Previously we have shown significant differences in lactation performance, mammary gland histology and gene expression profiles during ...
Benson Carolyn - - 2013
In the study of Crepeau et al.,(1) there are several findings of interest. These include both novel and confirmatory results: 1) the EEG classification had prognostic value for favorable and unfavorable outcomes; 2) patients with electrographic reactivity were much more likely to recover consciousness than those who did not; 3) ...
An Zhenguo - - 2013
Low density (0.55-0.92g/cm3, depending on the shell thickness and composition) glass-metal-metal triplex-shell hollow particles (TSHP) were prepared by a three-step route. Firstly, micron-sized silicate glass particles with hollow cores, uniform shells and high sphericity were prepared through spray drying and subsequent melting. NiP shell was uniformly assembled to the previously ...
Fendrych Matyás - - 2013
The exocyst complex, an effector of Rho and Rab GTPases, is believed to function as an exocytotic vesicle tether at the plasma membrane before SNARE complex formation. Exocyst subunits localize to secretory active regions of the plasma membrane, exemplified by the outer domain of Arabidopsis root epidermal cells. Using VAEM ...
Gupta Abhinaba - - 2013
Abstract: This article describes the separation of mixtures of fatty acid salts using a new organic solvent nanofiltration membrane based on polydicyclopentadiene (PDCPD). Mixtures of free fatty acids could not be separated by the membranes because they permeated at similar rates. When triisobutylamine was added to the fatty acids, the ...
Cunha-Bang C da - - 2013
(Val)ganciclovir is used to treat cytomegalovirus (CMV) infection following solid organ (SOT) or hematopoietic stem cell (HSCT) transplantation. Treatment failures occur, but the contribution from 39 known ganciclovir-related mutations (GRMs) in the CMV-UL97 gene remains controversial. We propose a categorization of these GRMs potentially useful when interpreting sequence analyses in ...
Guillo Pascal - - 2013
Tantalum polyhedral oligosilsesquioxane (POSS) complexes have been synthesised and characterized. X-ray structures of these complexes revealed that the coordination number of the tantalum center greatly affects the cube-like silsesquioxane framework.
Warner Adam - - 2013
We have identified cpna-1 (F31D5.3) as a novel essential muscle gene in the nematode C. elegans. Antibodies specific to CPNA-1, as well as a YFP translational fusion, are localized to integrin attachment sites (M-lines and dense bodies) in the body-wall muscle of C. elegans. CPNA-1 contains an N-terminal predicted transmembrane ...
Katayama Keisho - - 2013
The purpose of the present study was to clarify the influence of inspiratory resistive breathing during exercise under hypoxic condition on muscle sympathetic nerve activity (MSNA) and blood pressure (BP). Six healthy males completed this study. The subjects performed a submaximal exercise test using a cycle ergometer in a semi-recumbent ...
Kreepala C - - 2013
We hypothesized that measurement of previously defined acute kidney injury-induced transcripts at the time of implantation would add a new dimension to existing methods based on donor factors, histology and recipient factors. We analyzed microarray results from implantation biopsies taken after reperfusion from 70 kidneys from 53 deceased donors. We ...
Kodama Azusa - - 2013
Contrast-induced nephropathy (CIN), caused by a combination of the direct tubular toxicity of contrast media, a reduction in medullary blood flow, and the generation of reactive oxygen species, is a serious clinical problem. A need exists for effective strategies for its prevention. Thioredoxin-1 (Trx) is a low-molecular-weight endogenous redox-active protein ...
Losón Oliver C - - 2013
Several mitochondrial outer membrane proteins-Fis1, Mff, MiD49, and MiD51-have been proposed to promote mitochondrial fission by recruiting the GTPase Drp1, but fundamental issues remain concerning their function. A recent study supported such a role for Mff, but not for Fis1. In addition, it is unclear whether MiD49 and MiD51 activate ...
Song Nianhui - - 2013
Integrating quantum dots (QDs) into modern optoelectronic devices requires an understanding of how transparent conducting substrate affects the properties of QDs, especially their excited state dynamics. Here, the exciton quenching dynamics of core/multi-shell (CdSe/CdS3MLZnCdS2MLZnS2ML) quantum dots deposited on glass, tin oxide (SnO2), and antimony (Sb) doped tin oxide (ATO) films ...
Garratt Clifford J - - 2013
This is a commissioned review for 'A Year in Cardiology 2012', focusing on recent developments in the field of arrhythmias and pacing.
Bonsall David R - - 2013
The environmental day-night cycle provides the principal synchronizing signal for behavioral activity in most mammals. Light information is relayed to the master circadian pacemaker, the suprachiasmatic nucleus (SCN), via synaptic transmission from the retina directly to the SCN, where a predominately glutamate-driven cellular signaling pathway is able to reset biochemical, ...
Zhao Chuanqi - - 2013
G-quadruplex DNA is highly polymorphic. Its conformation transition is involved in a series of important life events. These controllable diverse structures also make G-quadruplex DNA a promising candidate as catalyst, biosensor, and DNA-based architecture. So far, G-quadruplex DNA-based applications are restricted done in aqueous media. Since many chemical reactions and ...
< 5 6 7 8 9 10 11 12 13 14 15 >