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Legostaeva Galina A - - 2013
Cobalt is a transition metal and an essential trace element that is required for vitamin B(12) biosynthesis, enzyme activation, and so on but is toxic in high concentrations. It was shown that the content of different elements in the plasma of 2-month-old BALB/c mice (control group) decreased in the following ...
Billaudeau Cyrille - - 2013
While intrinsic Brownian agitation within a lipid bilayer does homogenize the molecular distribution, the extremely diverse composition of the plasma membrane, in contrast, favors the development of inhomogeneity due to the propensity of such a system to minimize its total free energy. Precisely, deciphering such inhomogeneous organization with appropriate spatiotemporal ...
Shirasaki Yoshitaka - - 2013
The immune system is a very complex and dynamic cellular system, and its intricacies are considered akin to those of human society. Disturbance of homeostasis of the immune system results in various types of diseases; therefore, the homeostatic mechanism of the immune system has long been a subject of great ...
Ding Boyang - - 2013
Spectral and directional reshaping of fluorescence from dye molecules embedded in self-assembled hybrid plasmonic-photonic crystals has been examined. The hybrid crystals comprise 2-dimensional hexagonal arrays of dye-doped dielectric nanospheres, capped with silver semi-shells. Comparing the reshaped fluorescence spectra with measured transmission/reflection spectra and numerical calculations reveals that the spectral and ...
Schnier K E - - 2013
The transplant surgeon's decision to accept and utilize an organ typically is made within a constrained time window, explicitly cognizant of numerous health-related risks and under the potential influence of considerable regulatory and institutional pressures. This decision affects the health of two distinct populations, those patients receiving organ transplants and ...
Antfolk Christian - - 2013
One of the challenges facing prosthetic designers and engineers is to restore the missing sensory function inherit to hand amputation. Several different techniques can be employed to provide amputees with sensory feedback: sensory substitution methods where the recorded stimulus is not only transferred to the amputee, but also translated to ...
Gomez-Moyano Elisabeth - - 2013
Background  Poor prognostic factors in Merkel cell carcinoma include male sex, advanced stage at diagnosis, large tumor size (>5 mm), diffuse growth pattern, heavy lymphocytic infiltrate, and high mitotic rate. To date only six cases of Merkel cell carcinoma with sarcomatous or pseudosarcomatous differentiation and poor prognosis have been documented. ...
Boulet L-P - - 2013
The prevalence and incidence of asthma have increased among obese children and adults, particularly among women. Obesity seems to be a predisposing factor for the development of asthma, but the underlying mechanisms of its influence are still uncertain. Various hypotheses have been proposed to explain the link between obesity and ...
Hinderer Svenja - - 2013
Evaluation of: Elliott MJ, De Coppi P, Speggiorin S et al. Stem-cell-based, tissue engineered tracheal replacement in a child: a 2-year follow-up study. Lancet 380 (9846) 994-1000 (2012). Tissue-engineered tracheal transplants may offer a treatment strategy to address advanced structural disorders of the large airway. The approach aims to offer ...
Wyatt Sarah E - - 2013
Plant tropisms play a fundamental role in shaping the growth form of plants, and these fascinating movements are the focus of this thematic issue of the American Journal of Botany. The issue includes 16 reviews of the current literature and eight original manuscripts written by a diverse group of international ...
Nielsen Uffe N - - 2013
The polar regions are experiencing rapid climate change with implications for terrestrial ecosystems. Here, despite limited knowledge, we make some early predictions on soil invertebrate community responses to predicted twenty-first century climate change. Geographic and environmental differences suggest that climate change responses will differ between the Arctic and Antarctic. We ...
Schold J D - - 2013
Report cards evaluating transplant center performance have received significant attention in recent years corresponding with the Centers for Medicare and Medicaid Services issue of the 2007 Conditions of Participation. Our primary aim was to evaluate the association of report card evaluations with transplant center volume. We utilized data from the ...
Scott H A - - 2013
Obesity and asthma are associated conditions; however, the mechanisms linking the two remain unclear. Few studies have examined the effects of weight loss on inflammation and clinical outcomes in obese-asthma. To compare the effects of weight loss achieved by dietary restriction, exercise or combined dietary restriction and exercise on airway ...
Moazami Nader - - 2013
Heart transplantation remains the gold standard for long-term cardiac replacement, but a shortage of donor organs will always limit this option. For both transplant-eligible and noneligible patients, advances in mechanical circulatory support have revolutionized the options for the management of end-stage heart failure, and this technology continues to bring us ...
Dertlioğlu Selma Bakar - - 2013
Vitiligo and atopic dermatitis (AD) are two major cutaneous diseases that affect quality of life (QoL) by causing functional and psychosocial disorders. Our objective was to calculate Children's Dermatology Life Quality Index (CDLQI) scores in children with vitiligo and to compare these values with those in AD patients and healthy ...
Capobianchi M R - - 2013
Recent advances in nucleic acid sequencing technologies, referred to as 'next-generation' sequencing (NGS), have produced a true revolution and opened new perspectives for research and diagnostic applications, owing to the high speed and throughput of data generation. So far, NGS has been applied to metagenomics-based strategies for the discovery of ...
Marcilla Miguel - - 2013
Many physiological processes are regulated by dynamic protein interaction networks whose characterization provides valuable information on cell biology. Several strategies can be used to analyze protein-protein interactions. Among them, affinity purification combined with mass spectrometry (AP-MS) is arguably the most widely employed technique, not only owing to its high throughput ...
Ziaei M - - 2013
Prevention of slipping accidents requires provision of adequate friction through the use of suitable combinations of footwear and underfoot surfaces. Shoe sole tread groove is one of the important factors on friction coefficient during walking. To measure the effect of different shoe sole tread groove depths and different surfaces on ...
Miura Yoshinori - - 2013
The precursor protein of localized cutaneous amyloidosis (LCA) is believed to be cytokeratins on the basis of previous immunohistochemical studies. To identify the candidate amyloid protein biochemically, amyloid proteins were extracted with distilled water from lesional skin of LCA associated with Bowen's disease. The proteins were resolved on one- or ...
Deguine Jacques - - 2013
Natural killer (NK) cells are innate lymphocytes endowed with the capacity to survey and eliminate infected and transformed cells. Like T cells and B cells, NK cells fulfill their task by responding to soluble factors and to signals exchanged during cell-cell contacts. In this respect, cellular interactions established by NK ...
Taylor Christopher A - - 2013
Fatal infectious disease acquired during international travel is less likely to be captured through existing surveillance when diagnosis is delayed or missed, especially as autopsy rates decline. Death of a young girl owing to malaria demonstrates needs for increased examination of travel-related deaths through postmortem investigation, autopsy, and expanded surveillance.
Nienhaus G Ulrich - - 2013
Engineered nanoparticles (NPs) have found widespread application in technology and medicine. Whenever they come in contact with a living organism, interactions take place between the surfaces of the NPs and biomatter, in particular proteins, which are currently not well understood. We have introduced fluorescence correlation spectroscopy (FCS) and dual-focus FCS ...
Angevine Peter D - - 2013
The routine practice of neurosurgery generates a large amount of clinical data. The structured, systematic capture of this information using clinical registries or other rigorously designed observational studies can yield useful evidence to help improve the care of patients. Registries in particular can be designed to measure outcomes in real-world ...
Huisman Annemiek - - 2013
Until recently, suicides of mental health care users in the Netherlands had to be reported to the Health Care Inspectorate by treating clinicians and medical directors. Interview data from 38 clinicians who reported a suicide and directors of the 28 facilities where they worked indicated ambivalence about the procedure's usefulness, ...
Doulias Paschalis-Thomas - - 2013
Cysteine S-nitrosylation is a posttranslational modification by which nitric oxide regulates protein function and signaling. Studies of individual proteins have elucidated specific functional roles for S-nitrosylation, but knowledge of the extent of endogenous S-nitrosylation, the sites that are nitrosylated, and the regulatory consequences of S-nitrosylation remains limited. We used mass ...
Rosales Luis - - 2013
: In this work, we present a theoretical study of the transport properties of two finite and parallel armchair graphene nanoribbons connected to two semi-infinite leads of the same material. Using a single Π-band tight binding Hamiltonian and based on Green's function formalisms within a real space renormalization techniques, we ...
Abbas R A - - 2013
Informal employment is common in developing countries, including Egypt. This type of employment may have significant consequences on mental health. To determine the prevalence and risk factors of common mental disorders and substance abuse among temporary hired hospital cleaners. A cross-sectional study was conducted on 242 adult temporary cleaners and ...
Skorupski Nicole - - 2013
The purpose of this article is to increase awareness of osteoporosis incidence in patients with hip fracture among providers and allied health professionals, to increase osteoporosis recognition and treatment in post hip-fracture patients, and to provide guidance on how to improve continuity of care and collaboration between members of the ...
Grabowski Gregory - - 2013
Iliac crest bone graft has long been the standard adjunct used in spine fusion surgery. This graft provides osteogenic, osteoinductive, and osteoconductive elements that aid in creation of a fusion mass. However, morbidity associated with bone graft harvest has led surgeons to seek other potential adjuncts, including bone morphogenetic proteins, ...
Karnieli-Miller Orit - - 2013
Context  White coat ceremonies (WCCs) are widely prevalent as a celebration of matriculation in medical schools. Critics have questioned whether these ceremonies can successfully combine the themes of professionalism and humanism, as well as whether the white coat is an appropriate symbol. Objectives  This study aimed to add a process ...
Harrison Jon F - - 2013
Insect tracheal-respiratory systems achieve high fluxes and great dynamic range with low energy requirements and could be important models for bioengineers interested in developing microfluidic systems. Recent advances suggest that insect cardiorespiratory systems have functional valves that permit compartmentalization with segment-specific pressures and flows and that system anatomy allows regional ...
Felekyan Suren - - 2013
Fluorescence correlation spectroscopy (FCS) in combination with Förster resonance energy transfer (FRET) has been developed to a powerful statistical tool, which allows for the analysis of FRET fluctuations in the huge time of nanoseconds to seconds. FRET-FCS utilizes the strong distance dependence of the FRET efficiency on the donor (D)-acceptor ...
Groman Rachel F - - 2013
In an effort to rein in spending and improve patient outcomes, the US government and the private sector have adopted a number of policies over the last decade that hold health care professionals increasingly accountable for the cost and quality of the care they provide. A major driver of these ...
Appelbaum Paul S - - 2013
Anders Breivik's murder of 77 people in Norway in 2011 led to an unusual clash of interests. With conflicting psychiatric reports regarding his sanity, prosecutors argued that Breivik should be found not guilty by reason of insanity, whereas the defense strongly maintained that he was sane and responsible for his ...
Yaffe Michael B - - 2013
With input from the members of the Board of Reviewing Editors and editorial staff, Science Signaling puts the spotlight on the hottest signaling research of 2012. The connection between signaling and metabolism continues to be an important area. Signaling breakthroughs in cancer, immunology, developmental biology, neuroscience, and microbiology all made ...
Toyota Masatsugu - - 2013
Mechanical stress is a critical signal affecting morphogenesis and growth and is caused by a large variety of environmental stimuli such as touch, wind, and gravity in addition to endogenous forces generated by growth. On the basis of studies dating from the early 19th century, the plant mechanical sensors and ...
Piselli P - - 2013
Organ transplantation is an increasingly used medical procedure for treating otherwise fatal end-stage organ diseases with 107,000 transplants performed worldwide in 2010. A large number of newly developed anti-rejection drugs were developed. They prolong long-term survival of both the individual and the transplanted organ and constitute the main reason of ...
Jungbauer Alois - - 2013
This annual Methods and Advances Special Issue of Biotechnology Journal contains a selection of cutting-edge research and review articles with a particular emphasis on vertical process understanding - read more in this editorial by Prof. Alois Jungbauer, BTJ co-Editor-in-Chief.
Kim Mina - - 2013
Human dermal fibroblasts (HDFs) regulate wound-healing processes in human skin, including the regeneration of skin sensory fibres, in response to various mechanical stimuli. Because nerve growth factor (NGF) has an essential role in sensory regeneration, we evaluated the possible association of NGF with mechanical stimulus-dependent cellular responses in HDFs. A ...
Cumming Toby B - - 2013
Cognitive impairment after stroke is common and can cause disability with major impacts on quality of life and independence. There are also indirect effects of cognitive impairment on functional recovery after stroke through reduced participation in rehabilitation and poor adherence to treatment guidelines. In this article, we attempt to establish ...
Ochiai Hideo - - 2013
Glutathione S-transferase (GST) was found to complex with the Na(+) ,K(+) -ATPase as shown by binding assay using quartz crystal microbalance. The complexation was obstructed by the addition of antiserum to the α-subunit of the Na(+) ,K(+) -ATPase, suggesting the specificity of complexation between GST and the Na(+) ,K(+) -ATPase. ...
Minsky Shula - - 2013
This study investigated concordance between self-perceived and measured weight status for persons with serious mental illness. A total of 586 mental health clients assessed their weight as underweight, normal, overweight, or obese. The agreement between these self-assessments and the same categories based on measured body mass index was related to ...
Aziz Q - - 2013
Background  The microbial community of the human gut - the enteric microbiota - plays a critical role in functions that sustain health and is a positive asset in host defenses. In recent years, our understanding of this so-called human 'super organism' has advanced, following characterization of fecal metagenomes which identified ...
Purbhoo Marco A - - 2013
The immune synapse is central to the regulation of T-cell activation and effector functions. Vesicular compartments dynamically interact with the immune synapse. Here they take part in the trafficking of signaling components to and from the synaptic cleft, as well as in the directed delivery and release of T-cell effector ...
Yardley Sarah - - 2013
Context  Authentic early experience (AEE) describes experiences provided to new medical students to undertake 'human contact' to enhance learning. Although the concept of AEE is not new, and was commonplace prior to the Flexner Report of 1910, little is known about how or why meaning and knowledge are constructed through ...
Eisenberg Bob - - 2013
Ionic solutions are dominated by interactions because they must be electrically neutral, but classical theory assumes no interactions. Biological solutions are rather like seawater, concentrated enough so that the diameter of ions also produces important interactions. In my view, the theory of complex fluids is needed to deal with the ...
Li Huifang - - 2013
Androgen receptor (AR) plays a critical role in the development and progression of prostate cancer (PCa). The AR hormone-binding site (HBS) is intensively studied and represents the target area for the current antiandrogens including Bicalutamide and structurally related Enzalutamide. As resistance to antiandrogens invariably emerges in advanced prostate cancer, there ...
Bhardwaj M - - 2013
Noise, one of the major environmental nuisances, affects the learning ability of children negatively. With the assumption that in the existing German 4-type school system children are exposed to various noise levels in each type of school, we investigated the association between children's school type and environmental noise level. In ...
Oishi Motoharu - - 2013
The koala (Phascolarctos cinereus) and southern hairy-nosed wombat (Lasiorhinus latifrons) are iconic Australian fauna that share a close phylogenetic relationship but there are currently no comparative studies of the seminiferous epithelial cell or testicular microanatomy of either species. Koala and wombat spermatozoa are unusual for marsupials as they possess a ...
Pascal M - - 2013
Despite the frequency and severity of peanut allergy, the only approved treatment is strict avoidance. Different types of immunotherapy with crude peanut extract are not universally effective and have been associated with relatively high adverse reaction rates. We sought to determine whether in silico predictive algorithms were useful in identifying ...
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