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Tian He - - 2013
In this paper, we employed Ramen spectroscopy to monitor oxygen movement at the electrode/oxide interface by inserting single-layer graphene (SLG). Raman area mapping and single point measurements show noticeable changes in the D-band, G-band, and 2D-band signals of the SLG during consecutive electrical programming repeated for 9 cycles. In addition, ...
Canneyt Koen Van - - 2013
Double lumen (DL) central venous catheters (CVC) often suffer from thrombosis, fibrin sheet formation, and/or suction towards the vessel wall, resulting in insufficient blood flow during hemodialysis. Reversing the catheter connection often restores blood flows, but will lead to higher recirculation. Single lumen (SL) CVCs have often fewer flow problems, ...
Ken Soléakhéna - - 2013
ABSTRACT: BACKGROUND: To integrate 3D MR spectroscopy imaging (MRSI) in the treatment planning system (TPS) for glioblastoma dose painting to guide simultaneous integrated boost (SIB) in intensity-modulated radiation therapy (IMRT). METHODS: For sixteen glioblastoma patients, we have simulated three types of dosimetry plans, one conventional plan of 60-Gy in 3D ...
Gil-Ibáñez Blanca - - 2013
BACKGROUND: This work assessed the role of robotic-assisted lapararoscopic radical hysterectomy in the treatment of early invasive cervical cancer with special regard to nerve sparing technique. METHODS: Between October 2009 and June 2011, a total of 14 non-consecutive patients underwent early cervical cancer surgery at the authors' institution. Patients with ...
Duman Deniz Güney - - 2013
Saccharomyces boulardii is a probiotic used for the prevention of antibiotic-associated diarrhoea. We aimed to investigate whether S. boulardii could alter the effects of clarithromycin (CLA) and methotrexate (MTX) on oro-caecal intestinal transit and oxidative damage in rats. Rats were divided into two groups receiving a single dose of MTX ...
Zogopoulos Panagiotis - - 2013
The endocannabinoid system (ES) is comprised of cannabinoid (CB) receptors, their endogenous ligands (endocannabinoids), and proteins responsible for their metabolism. Endocannabinoids serve as retrograde signaling messengers in GABAergic and glutamatergic synapses, as well as modulators of postsynaptic transmission, that interact with other neurotransmitters. Physiological stimuli and pathological conditions lead to ...
Boesmans W - - 2013
Background  The intimate association between glial cells and neurons within the enteric nervous system has confounded careful examination of the direct responsiveness of enteric glia to different neuroligands. Therefore, we aimed to investigate whether neurotransmitters known to elicit fast excitatory potentials in enteric nerves also activate enteric glia directly. Methods  ...
Kumode Takahiro - - 2013
Abstract Primary effusion lymphoma (PEL) is a rare type of non-Hodgkin lymphoma that usually develops in immunosuppressed patients infected with human herpes virus 8 (HHV8) in conjunction with human immunodeficiency virus (HIV) infection. However, there are several reports of HHV-8-related HIV-negative cases and HHV8-unrelated HIV-negative cases, mainly in immunodeficient and ...
Lee Jungkyu K - - 2013
Back and forth: Enzymatic, reversible polymerization on gold surfaces was efficiently carried out from surface-tethered self-priming oligodeoxynucleotides in a sequence-specific fashion by using two kinds of enzymes. Taq DNA polymerase, acting as a catalyst, facilitated DNA polymerization, and DNA restriction enzymes cut DNA polymers from the surface.
Nagase Hiroaki - - 2013
OBJECTIVE: To identify predictors of the development of neurologic damage in children with febrile seizures or altered consciousness within 6 hours of onset. METHODS: Our study included 86 children (4-159 months old), who fulfilled the diagnostic criteria for complex febrile seizures on admission to our department between October 2002 and ...
Ma R - - 2013
Gliomas are the most common primary central nervous system tumour seen in adults. There have been many advances over the last two decades as we widen our search for a molecular basis of gliomagenesis. Many biomarkers have been discovered to be important in the management of gliomas, including 1p19q co-deletion, ...
Huang Hui-Tzu - - 2013
AIMS AND OBJECTIVES: To delineate the trajectories of functional status over four time points and to examine predictors of functional decline (FD) in hospitalised older patients. BACKGROUND: About 30-60% of the older patients develop new dependence in activities of daily living (ADL) during a hospital stay, which results in progressive ...
Schrijvers L H - - 2013
Long-term adherence to prophylactic therapy is the key to successful prevention of bleeds in severe haemophilia. The present study aims to provide a systematic review of the literature on the determinants of adherence to prophylaxis in haemophilia. A literature search in the largest medical databases in Oct 2011 yielded 880 ...
Jansson Erik T - - 2013
ABSTRACT: The TRPV1 ion channel is expressed in nociceptors, where pharmacological modulation of its function may offer a means of alleviating pain and neurogenic inflammation processes in the human body. The aim of this study was to investigate the effects of cholesterol depletion of the cell on ion-permeability of the ...
Mindlin M J - - 2013
SUMMARY In August 2008 an outbreak of Salmonella Typhimurium DT104 occurred in South West London. Sixteen cases were identified with a particular multilocus variable number tandem repeat analysis (MLVA) pattern. In a matched case-control study 14 primary cases were included. These were defined as individuals with gastrointestinal symptoms and Salmonella ...
Pretorius Etheresia - - 2013
Abstract Aims: Inflammatory diseases associated with iron overload, are characterized by a changed coagulation profile, where there is a persistent presence of fibrin-like material of dense matted deposits. It is believed that one source of such material is a result of the activation of blood coagulation without the generation of ...
Georgiadis George S - - 2013
Hybrid endografting in endovascular abdominal aortic aneurysm repair (EVAR) is defined as the process of placing a series of two or more different types of covered stents, usually to treat a complex abdominal aortic aneurysm (AAA) or a primary or secondary endoleak. We describe the treatment of a type III, ...
Macy Alexandra S - - 2013
Obsessive-compulsive disorder (OCD) has a profound impact with a high disease burden. In order to truly understand the scope of the effect OCD has on the patient population, one must take into account not only the relentless symptoms beleaguering the patients but also examine their overall ability to enjoy their ...
Ram Ron - - 2013
Abstract Acute graft versus host disease (GVHD) has been, and continues to compromise the benefits associated with allogeneic hematopoietic cell transplantation to cure malignant and non-malignant diseases. Pharmacologic interventions to prevent GVHD have emerged as a major objective of research in the immunology and transplantation fields. A better understanding of ...
Athanasiadis G - - 2013
BACKGROUND: β(2) -Glycoprotein I (β(2) -GPI), also designated apolipoprotein H, is a 50-kDa protein that circulates in blood at high concentrations, playing an important role in autoimmune diseases, hemostasis, atherogenesis and angiogenesis, as well as in host defense against bacteria and in protein/cellular waste removal. Plasma β(2) -GPI levels have ...
Stoiber Martin - - 2013
Aim: Transparent hollow models are needed to visualize and quantify flow in various applications. To obtain the final transparent model, an intermediate molding of the fluid space with an easily removable material is required. Currently used materials to produce this intermediate molding have limitations: toxicity, cost, and a tendency to ...
Petrov Vesselin - - 2013
The complete determination of all rate and equilibrium constants of the network of reversible chemical reactions involving the anthocyanin analogue, 3',4'-dihydroxy-7-O-β-d-glucopyranosyloxyflavylium chloride, was achieved by means of UV-visible spectroscopy, flash photolysis and pH jumps monitored by stopped-flow. An energy level diagram containing all the data was obtained. A detailed step ...
Liu Li-Yan - - 2013
BACKGROUND AND AIM: The significance of ABCB11 variants have been studied in some cholestatic diseases, but is not clear in transient neonatal cholestasis (TNC). The aim of the present study is to explore the association between ABCB11 variants and TNC. METHODS: It is a case-control study. 192 children with TNC ...
Kulkarni Ketan P - - 2013
PURPOSE: The objective is to describe our management experience of children with appendix carcinoids (AC). METHOD: We first performed a systematic review of the literature pertaining to appendix carcinoids in the pediatric population. PubMed, EMBBASE and SCOPUS and most significant Congress proceedings were reviewed. In addition we retrieved the charts ...
Zachaki Sophia - - 2013
Abstract Models for the pathogenesis of Myelodysplastic Syndromes (MDS) imply the role of individual genetic variations in genes involved in detoxification mechanisms. GSTP1 enzyme plays a key role in biotransformation of a variety of carcinogens. The corresponding gene is subject to a single-nucleotide polymorphism (A(313)G) leading to abolished enzyme activity. ...
Yashiro Masatomo - - 2013
Purpose: Bioimpedance spectroscopy (BIS) is widely used to assess fluid status in hemodialysis (HD) patients. Our purpose is to evaluate filtration coefficients (Lpst) as an alternative test to assess fluid status by utilizing BIS as a reference test.
Methods: 106 HD patients (determined group) were divided into two groups with (EX ...
Behrmann-Godel Jasminca - - 2013
SUMMARY Identification of parasite species is particularly challenging in larval and juvenile hosts, and this hampers the understanding of parasite acquisition in early life. The work described here employs a new combination of methods to identify parasite species and study parasite succession in fry of perch (Perca fluviatilis) from Lake ...
Masuda Paula Y - - 2013
Background: The epidemiology and clinical features of brachioradial pruritus are variably described in the literature. We sought to analyze these features in a large group of Brazilian patients. Patients and Methods: In a descriptive, observational study, we identified all patients with a final diagnosis of brachioradial pruritus seen over a ...
Zhu Jianxi - - 2013
ABSTRACT: BACKGROUND: The inactivation of c-Jun N-terminal kinase (JNK) is associated with anti-apoptotic and anti-inflammatory effects in cerebral ischemia, which can be induced by an imbalance between upstream phosphatases and kinases.Result: Mitogen-activated protein kinase phosphatase 7 (MKP-7) was upregulated significantly at 4 h of reperfusion postischemia in rat hippocampi. By ...
Takahashi Daijiro - - 2013
BACKGROUND: The measurement of soluble fibrin monomer complex (SFMC) and fibrin monomer (FM) are well known as markers for a hypercoagulability state, but such measurements have not been investigated in detail for the neonate. To discern a hypercoagulability state among sick newborns, we studied the behavior of SFMC with special ...
Teets Thomas S - - 2013
Oxygenation of Ir(2)(II,II)(tfepma)(2)(CN(t)Bu)(2)Cl(3)H (, tfepma = CH(3)N[P(OCH(2)CF(3))(2)](2)) furnishes Ir(2)(II,II)(tfepma)(2)(CN(t)Bu)(2)Cl(3)(OOH) (), the first isolable iridium hydroperoxo complex. This complex transfers an oxygen atom to triphenylphosphine, producing triphenylphosphine oxide and Ir(2)(II,II)(tfepma)(2)(CN(t)Bu)(2)Cl(3)(OH) () in high yield. Reaction of with acid induces cleavage of the O-O bond, initially forming [Ir(2)(II,II)(tfepma)(2)(CN(t)Bu)(2)Cl(3)(OH(2))]Cl (), which was identified ...
Assaf Chalid - - 2013
Background: Systemic treatment with pegylated liposomal doxorubicin is an established second-line treatment of advanced cutaneous T-cell lymphoma. Pegylated liposomal doxorubicin (PLD) is currently unavailable, therefore, clinical studies investigating the efficacy of non-pegylated liposomal formula (NPLD) have been analyzed. Methods: Since clinical trials comparing PLD and NPLD in CTCL do not ...
Cooney Adeline - - 2013
AIMS AND OBJECTIVES: To understand the meaning of chronic obstructive pulmonary disease (COPD) for people and their response to this disease. BACKGROUND: COPD is a major cause of disability and death. The symptoms of COPD have the potential to impact on every aspect of a person's day-to-day life. To date ...
Ortiz Fernanda - - 2013
Background: TGF-β1 expression has been described to increase along with time from transplantation and has also been linked to allograft dysfunction and toxic effects of cyclosporine. Our aim was to correlate intragraft TGF-β1 expression with cyclosporine exposure after kidney transplantation.
Methods: Altogether 53 kidney allograft protocol biopsies from 42 patients on ...
Totaro Pasquale - - 2013
Propeller-like [Fe(4)(L)(2)(dk)(6)] complexes, in which Hdk is a β-diketone and H(3)L is a tripodal alcohol, R-C(CH(2)OH)(3), exhibit tunable magnetic anisotropy barriers and retain their magnetic memory effect when chemically anchored on metal surfaces. Heteronuclear analogues of these M(4) complexes have been sought to afford a library of compounds with different ...
Foss Francine M - - 2013
ABSTRACT This phase II study to determine the safety and efficacy of denileukin diftitox (DD) and CHOP enrolled patients with newly diagnosed peripheral T-cell lymphoma (PTCL). Forty-nine received DD 18 µg/kg/day (days 1, 2) with CHOP (day 3) every 21 days ≤6-8 cycles. Intent-to-treat (ITT) and safety populations comprised all ...
Giaroni C - - 2013
Background  Intestinal ischemia and reperfusion (I/R) injury leads to abnormalities in motility, namely delay of transit, caused by damage to myenteric neurons. Alterations of the nitrergic transmission may occur in these conditions. This study investigated whether an in vitro I/R injury may affect nitric oxide (NO) production from the myenteric ...
Ertl Gerhard - - 2013
Scratching the surface: For over 100 years the interactions of molecules at surfaces have been studied at the Fritz Haber Institute of the Max Planck Society, Berlin. Nobel Laureate Gerhard Ertl looks back at some of the key developments in this time, and the people who made them.
Karuputhula Narendra Babu - - 2013
Studies on elevated reactive oxygen species (ROS) levels in granulosa cells (GC) and its subsequent effect on fertilization are limited. Oxidative stress (OS) mediated alterations in GC of infertile women undergoing in vitro fertilization (IVF) and embryo transfer (ET) was investigated. GC were obtained from 28 women with endometriosis (Group ...
Stephansson Olof - - 2013
Maternal psychiatric disease is associated with adverse pregnancy outcomes. Use of selective serotonin reuptake inhibitors (SSRIs) during pregnancy has been associated with congenital anomalies, neonatal withdrawal syndrome, and persistent pulmonary hypertension of the newborn. However, the risk of stillbirth and infant mortality when accounting for previous maternal psychiatric disease remains ...
Torimoto Keiichi - - 2013
ABSTRACT: BACKGROUND: Fluctuations in blood glucose level cause endothelial dysfunction and play a critical role in onset and/or progression of atherosclerosis. We hypothesized that fluctuation in blood glucose levels correlate with vascular endothelial dysfunction and that this relationship can be assessed using common bedside medical devices. METHODS: Fluctuations in blood ...
Belling Franziska - - 2013
Purpose: Thrombin mediates an excess in the production of neoangiogenetic (VEGF) and profibrotic (PAI-1) factors in human peritoneal mesothelial cells (HMC). The mechanisms leading to this overproduction have not been elucidated so far; in the context of peritoneal dialysis it can result in impaired peritoneal membrane function. 
Objectives: This study ...
Lester Jean - - 2013
PURPOSE: This study characterizes drug safety-related label changes by evidence source contribution, time from drug approval to label change, initiator (FDA or sponsor), and drug class. METHODS: A retrospective review of the FDA's internal files was used to obtain regulatory documentation on drugs undergoing a 2010 label change. Contribution of ...
Fakhratova Malika - - 2013
ABSTRACT Purpose: To determine the cause of Leber congenital amaurosis (LCA) in a consanguineous Emirati family. Methods: The clinical diagnosis was made on the basis of medical history, ophthalmoscopy and standard ERG. The diagnosis was confirmed by molecular genetic analysis of known LCA genes by Next-Generation Sequencing (NGS). The latter ...
Abu-Kishk Ibrahim - - 2013
BACKGROUND: It is common practice for patients to be admitted to the intensive care unit following scoliosis surgery, because of the prolonged anesthesia, the need for efficient pain control and the known immediate postoperative complications. However, this may be unnecessary in many patients. PURPOSE: We aimed to establish possible associations ...
Elwell Laura - - 2013
Objective This study was designed to examine patients' and health professionals' perspectives on lifestyle behaviour change and to inform the development of a lifestyle behaviour change intervention to be used in primary care. Design Focus groups were conducted with seven patients and 13 health professionals where they were asked to ...
Stegmayr Bernd G - - 2013
Background: The blood membrane interaction induced during hemodialysis (HD) activates the coagulation system. To prevent clotting and to maintain dialyzer patency, an anticoagulant such as tinzaparin is used. To increase patency of the dialyzers and to reduce the risk of bleeding related to anticoagulation, citrate-containing dialysate has been introduced in ...
Danielsen Anne K - - 2013
AIMS AND OBJECTIVES: To examine patients' experiences of impact of a temporary stoma on their everyday life. Furthermore, we wanted to generate new knowledge and comprehension of learning how to live with a temporary stoma. BACKGROUND: There are many aspects, largely unexplored, that may influence patients' adaptation to life with ...
Lewis Fiona M - - 2013
Background: Neonatal screening for galactosaemia (GAL) identifies the condition early, but subsequent biomedical and genetic testing fails to identify which subgroup of infants with GAL are at most risk of the language disorders associated with the condition. This study aims to present preliminary data on an infant with GAL based ...
Golus Joanna - - 2013
Objectives: This study aims to examine biofilm formed on vascular prostheses by Staphylococcus epidermidis with different ica and aap genetic status, and to evaluate the effect of antibiotic-modified prostheses on bacterial colonization.
Methods: Biofilm formation was determined using fluorescence microscopy imaging. Quantitative analysis was conducted using the biofilm coverage ratio (BCR) ...
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