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Segade P - - 2013
SUMMARY Heliciculture is an excellent alternative to obtain edible snails but its viability is seriously threatened by pathogens. A parasitological survey was conducted in 3 mixed system-based heliciculture farms in Galicia (NW Spain), with the species Tetrahymena rostrata, Tetrahymena limacis, Tetratrichomonas limacis, Cryptobia helicogenae, Brachylaima aspersae (metacercariae and sporocysts), Alloionema ...
Cosnier Frédéric - - 2013
Abstract 1. Toluene (TOL) is a neurotoxic, ototoxic and reprotoxic solvent which is metabolized via the glutathione pathway, producing benzylmercapturic, o-, m- and p-toluylmercapturic acids (MAs). These metabolites could be useful as biomarkers of TOL exposure. 2. The aims of this study were (1) to provide data on MAs excretion ...
Liu Liang Q - - 2013
The Consolidated Standards of Reporting Trials (CONSORT) statement was developed to improve the reporting quality of randomized controlled trials (RCTs). Our primary aim was to assess to what extent reports of RCTs in solid organ transplantation adhere to the 2010 CONSORT statement. Secondly, we investigated the relationship between CONSORT adherence, ...
Behrmann-Godel Jasminca - - 2013
SUMMARY Identification of parasite species is particularly challenging in larval and juvenile hosts, and this hampers the understanding of parasite acquisition in early life. The work described here employs a new combination of methods to identify parasite species and study parasite succession in fry of perch (Perca fluviatilis) from Lake ...
Masuda Paula Y - - 2013
Background: The epidemiology and clinical features of brachioradial pruritus are variably described in the literature. We sought to analyze these features in a large group of Brazilian patients. Patients and Methods: In a descriptive, observational study, we identified all patients with a final diagnosis of brachioradial pruritus seen over a ...
Nomura Tomoe - - 2013
ABSTRACT: BACKGROUND: Aberrant methylation patterns in CpG island are known to be influential in gene silencing. Histamine plays important physiological roles in the upper gastrointestinal tract and acts via the H2 receptor. We report an investigation into the effect of HRH2 promoter polymorphism (rs2607474 G > A) on the methylation ...
Shakhssalim Nasser - - 2013
Purpose: Numerous synthetic materials have been used for the bladder reconstruction; of which, nano-structured scaffolds are used as relevant implant to the bladder tissue-engineering. The aim of this study was to investigate the capacity of Poly ε-caprolactone/poly-L-lactide acid (PCL/PLLA) nanofibrous scaffold, in supporting the maintenance and attachment of the human ...
Duran Jordi J Institute for Research in Biomedicine (IRB Barcelona) Barcelona, Barcelona, - - 2013
Glycogen is the only carbohydrate reserve of the brain, but its overall contribution to brain functions remains unclear. Although it has traditionally been considered as an emergency energetic reservoir, increasing evidence points to a role of glycogen in the normal activity of the brain. To address this long-standing question, we ...
Yashiro Masatomo - - 2013
Purpose: Bioimpedance spectroscopy (BIS) is widely used to assess fluid status in hemodialysis (HD) patients. Our purpose is to evaluate filtration coefficients (Lpst) as an alternative test to assess fluid status by utilizing BIS as a reference test.
Methods: 106 HD patients (determined group) were divided into two groups with (EX ...
Li Qiongyu - - 2013
The growth of bilayer and multilayer graphene on copper foils was studied by isotopic labeling of the methane precursor. Isotope-labeled graphene films were characterized with micro-Raman mapping and Time-of-Flight Secondary Ion Mass Spectrometry (TOF SIMS). During growth at high temperature the adlayers formed simultaneously and beneath the top, continuous layer ...
Krishnakumar S - - 2013
The objective of this study was to determine the duration for which sperm from the North American bison (Bison bison) could be chilled prior to being cryopreserved, without compromising post- thaw sperm quality. This would permit transport of samples collected remotely, to the laboratory (at 4°C) for cryopreservation. Epididymal sperm ...
Drago Lorenzo - - 2013
Purpose: Staphylococcus aureus and Pseudomonas aeruginosa are frequently isolated from biofilm-associated orthopedic implant infections. This study assessed the activity of N-acetyl-L-cysteine at inhibitory and subinhibitory concentrations against biofilm formed by S. aureus and P. aeruginosa on prosthetic materials.
Methods: S. aureus and P. aeruginosa biofilm on smooth polyethylene and sand-blasted titanium ...
Bueters Tjerk - - 2013
Abstract 1. Intestinal loss, 1 - (F(obs)/f(H)), is the missing fraction of the dose that is unexplained by systemic clearance. Here, we investigated whether intestinal loss in rat is predictive for human, and whether intestinal metabolism explained observed differences between rat and human. 2. For 81 marketed drugs, human and rat intestinal loss values ...
Slight Samantha R - - 2013
One third of the world's population is infected with Mycobacterium tuberculosis (Mtb). Although most infected people remain asymptomatic, they have a 10% lifetime risk of developing active tuberculosis (TB). Thus, the current challenge is to identify immune parameters that distinguish individuals with latent TB from those with active TB. Using ...
Priori Silvia G SG Division of Cardiology and Molecular Cardiology, Maugeri Foundation-University of Pavia, Via Maugeri 10/10°, 27100 Pavia, Italy. - - 2013
The discovery of the genetic basis of inherited arrhythmias has paved the way for an improved understanding of arrhythmogenesis in a wide spectrum of life-threatening conditions. In vitro expression of mutations and transgenic animal models have been instrumental in enhancing this understanding, but the applicability of results to the human ...
Hounton Sennen - - 2013
ABSTRACT: Current methods for estimating maternal mortality lack precision, and are not suitable for monitoring progress in the short run. In addition, national maternal mortality ratios (MMRs) alone do not provide useful information on where the greatest burden of mortality is located, who is concerned, what are the causes, and ...
Couturier-Maillard Aurélie A University Lille Nord de France, Lille, - - 2013
Instability in the composition of gut bacterial communities (dysbiosis) has been linked to common human intestinal disorders, such as Crohn's disease and colorectal cancer. Here, we show that dysbiosis caused by Nod2 deficiency gives rise to a reversible, communicable risk of colitis and colitis-associated carcinogenesis in mice. Loss of either ...
Morel Mélanie M Université de Lorraine, IAM, UMR 1136, IFR 110 EFABA, Vandoeuvre-lès-Nancy, F-54506, France. - - 2013
Fungal degradation of wood is mainly restricted to basidiomycetes, these organisms having developed complex oxidative and hydrolytic enzymatic systems. Besides these systems, wood-decaying fungi possess intracellular networks allowing them to deal with the myriad of potential toxic compounds resulting at least in part from wood degradation but also more generally ...
Avalos Alicia - - 2013
Abstract Silver nanoparticles (AgNPs), which have well-known antimicrobial properties, are extensively used in various medical and general applications. Despite the widespread use of AgNPs, relatively few studies have been undertaken to determine the toxicity effects of AgNPs exposure. The aim of the present work was to study how AgNPs interact ...
Ikeda Mari - - 2013
The effects of the structures of HgX(2) complexes (X = CF(3)SO(3) and Cl) with chiral bidentate ligands [(R)-(-)-1-(1-naphthyl)-N,N-bis(pyridin-4-ylmethyl)ethanamine, (R)-(+)-1-phenyl-N,N-bis(pyridin-4-ylmethyl)ethanamine, (R)-(-)-1-(1-naphthyl)-N,N-bis(pyridin-3-ylmethyl)ethanamine, and (R)-(+)-1-phenyl-N,N-bis(pyridin-4-ylmethyl)ethanamine] on circular dichroism (CD) spectra are reported. The CD spectra of free (R)-(-)- and (R)-(+)-, which have 4-pyridyl groups, are similar to those of (R)-(-)- and (R)-(+)-, which ...
Macy Alexandra S - - 2013
Obsessive-compulsive disorder (OCD) has a profound impact with a high disease burden. In order to truly understand the scope of the effect OCD has on the patient population, one must take into account not only the relentless symptoms beleaguering the patients but also examine their overall ability to enjoy their ...
Mindlin M J - - 2013
SUMMARY In August 2008 an outbreak of Salmonella Typhimurium DT104 occurred in South West London. Sixteen cases were identified with a particular multilocus variable number tandem repeat analysis (MLVA) pattern. In a matched case-control study 14 primary cases were included. These were defined as individuals with gastrointestinal symptoms and Salmonella ...
Pretorius Etheresia - - 2013
Abstract Aims: Inflammatory diseases associated with iron overload, are characterized by a changed coagulation profile, where there is a persistent presence of fibrin-like material of dense matted deposits. It is believed that one source of such material is a result of the activation of blood coagulation without the generation of ...
Albert Barbara - - 2013
"…︁ Contemplating the ideas published in Angewandte Chemie as well as the concepts and visions that can be derived from them allows us to experience cutting-edge chemistry. …︁" Read more in the Editorial by Barbara Albert.
Golus Joanna - - 2013
Objectives: This study aims to examine biofilm formed on vascular prostheses by Staphylococcus epidermidis with different ica and aap genetic status, and to evaluate the effect of antibiotic-modified prostheses on bacterial colonization.
Methods: Biofilm formation was determined using fluorescence microscopy imaging. Quantitative analysis was conducted using the biofilm coverage ratio (BCR) ...
Hajjar Roger J RJ Cardiovascular Research Center, Mount Sinai School of Medicine, One Gustave Levy Place, Box 1030, New York, New York 10029, USA. - - 2013
Advances in understanding the molecular basis of myocardial dysfunction, together with the evolution of increasingly efficient gene transfer technology, make gene-based therapy a promising treatment option for heart conditions. Cardiovascular gene therapy has benefitted from recent advancements in vector technology, design, and delivery modalities. There is a critical need to ...
Petrov Vesselin - - 2013
The complete determination of all rate and equilibrium constants of the network of reversible chemical reactions involving the anthocyanin analogue, 3',4'-dihydroxy-7-O-β-d-glucopyranosyloxyflavylium chloride, was achieved by means of UV-visible spectroscopy, flash photolysis and pH jumps monitored by stopped-flow. An energy level diagram containing all the data was obtained. A detailed step ...
Liu Li-Yan - - 2013
BACKGROUND AND AIM: The significance of ABCB11 variants have been studied in some cholestatic diseases, but is not clear in transient neonatal cholestasis (TNC). The aim of the present study is to explore the association between ABCB11 variants and TNC. METHODS: It is a case-control study. 192 children with TNC ...
Kulkarni Ketan P - - 2013
PURPOSE: The objective is to describe our management experience of children with appendix carcinoids (AC). METHOD: We first performed a systematic review of the literature pertaining to appendix carcinoids in the pediatric population. PubMed, EMBBASE and SCOPUS and most significant Congress proceedings were reviewed. In addition we retrieved the charts ...
Zhu Jianxi - - 2013
ABSTRACT: BACKGROUND: The inactivation of c-Jun N-terminal kinase (JNK) is associated with anti-apoptotic and anti-inflammatory effects in cerebral ischemia, which can be induced by an imbalance between upstream phosphatases and kinases.Result: Mitogen-activated protein kinase phosphatase 7 (MKP-7) was upregulated significantly at 4 h of reperfusion postischemia in rat hippocampi. By ...
Takahashi Daijiro - - 2013
BACKGROUND: The measurement of soluble fibrin monomer complex (SFMC) and fibrin monomer (FM) are well known as markers for a hypercoagulability state, but such measurements have not been investigated in detail for the neonate. To discern a hypercoagulability state among sick newborns, we studied the behavior of SFMC with special ...
Teets Thomas S - - 2013
Oxygenation of Ir(2)(II,II)(tfepma)(2)(CN(t)Bu)(2)Cl(3)H (, tfepma = CH(3)N[P(OCH(2)CF(3))(2)](2)) furnishes Ir(2)(II,II)(tfepma)(2)(CN(t)Bu)(2)Cl(3)(OOH) (), the first isolable iridium hydroperoxo complex. This complex transfers an oxygen atom to triphenylphosphine, producing triphenylphosphine oxide and Ir(2)(II,II)(tfepma)(2)(CN(t)Bu)(2)Cl(3)(OH) () in high yield. Reaction of with acid induces cleavage of the O-O bond, initially forming [Ir(2)(II,II)(tfepma)(2)(CN(t)Bu)(2)Cl(3)(OH(2))]Cl (), which was identified ...
Iavarone Federica - - 2013
Analysis by HPLC-ESI-MS top-down proteomic platform of specimens of human preterm newborn whole saliva evidenced high relative amounts of cystatin B and its S-glutathionylated, S-cysteinylated and S-S 2-mer (on Cys3) derivatives, decreasing as function of post-conceptional age (PCA). The percentage of S-unmodified cystatin B was higher than the S-modified isoforms ...
Duprez Veerle - - 2013
AIMS AND OBJECTIVES: To develop a set of psychometrically sound instruments to assess knowledge, self-management and self-efficacy of diabetic patients. Furthermore, a survey to evaluate the satisfaction about diabetes education for patients was developed and tested. BACKGROUND: Treatment and secondary prevention of diabetes require a complex combination of care components. ...
Seo Ji-Hyun - - 2013
BACKGROUND: The antimicrobial resistance capability of Helicobacter pylori is one of the critical factors in the failure to treat this pathogen. The purpose of this study was to investigate the changing pattern of primary antibiotic resistance rates in children in the southern central part of South Korea from 1990-2009. METHODS: ...
Donato Maria Francesca - - 2013
Background: Hepatitis C virus infection is associated with a variety of extrahepatic disorders such as membrano-proliferative glomerulonephritis, which is generally due to cryoglobulinemia. 
Setting: We describe the case of one liver transplant recipient who received antiviral therapy (subcutaneous administration of peg-IFN-alpha-2a 180 mcg weekly and oral ribavirin 200 mg thrice ...
Marks Andrew R AR Department of Physiology and Cellular Biophysics and The Clyde and Helen Wu Center for Molecular Cardiology, College of Physicians and Surgeons of Columbia University, New York, New York 10032, USA. - - 2013
Ca2+-dependent signaling is highly regulated in cardiomyocytes and determines the force of cardiac muscle contraction. Ca2+ cycling refers to the release and reuptake of intracellular Ca2+ that drives muscle contraction and relaxation. In failing hearts, Ca2+ cycling is profoundly altered, resulting in impaired contractility and fatal cardiac arrhythmias. The key ...
Athanasiadis G - - 2013
BACKGROUND: β(2) -Glycoprotein I (β(2) -GPI), also designated apolipoprotein H, is a 50-kDa protein that circulates in blood at high concentrations, playing an important role in autoimmune diseases, hemostasis, atherogenesis and angiogenesis, as well as in host defense against bacteria and in protein/cellular waste removal. Plasma β(2) -GPI levels have ...
Stoiber Martin - - 2013
Aim: Transparent hollow models are needed to visualize and quantify flow in various applications. To obtain the final transparent model, an intermediate molding of the fluid space with an easily removable material is required. Currently used materials to produce this intermediate molding have limitations: toxicity, cost, and a tendency to ...
Ertl Gerhard - - 2013
Scratching the surface: For over 100 years the interactions of molecules at surfaces have been studied at the Fritz Haber Institute of the Max Planck Society, Berlin. Nobel Laureate Gerhard Ertl looks back at some of the key developments in this time, and the people who made them.
Karuputhula Narendra Babu - - 2013
Studies on elevated reactive oxygen species (ROS) levels in granulosa cells (GC) and its subsequent effect on fertilization are limited. Oxidative stress (OS) mediated alterations in GC of infertile women undergoing in vitro fertilization (IVF) and embryo transfer (ET) was investigated. GC were obtained from 28 women with endometriosis (Group ...
Assaf Chalid - - 2013
Background: Systemic treatment with pegylated liposomal doxorubicin is an established second-line treatment of advanced cutaneous T-cell lymphoma. Pegylated liposomal doxorubicin (PLD) is currently unavailable, therefore, clinical studies investigating the efficacy of non-pegylated liposomal formula (NPLD) have been analyzed. Methods: Since clinical trials comparing PLD and NPLD in CTCL do not ...
Cooney Adeline - - 2013
AIMS AND OBJECTIVES: To understand the meaning of chronic obstructive pulmonary disease (COPD) for people and their response to this disease. BACKGROUND: COPD is a major cause of disability and death. The symptoms of COPD have the potential to impact on every aspect of a person's day-to-day life. To date ...
Bishop D V M DV Department of Experimental Psychology, University of Oxford, Oxford, UK. - - 2013
Our ability to look at structure and function of a living brain has increased exponentially since the early 1970s. Many studies of developmental disorders now routinely include a brain imaging or electrophysiological component. Amid current enthusiasm for applications of neuroscience to educational interventions, we need to pause to consider what ...
Ortiz Fernanda - - 2013
Background: TGF-β1 expression has been described to increase along with time from transplantation and has also been linked to allograft dysfunction and toxic effects of cyclosporine. Our aim was to correlate intragraft TGF-β1 expression with cyclosporine exposure after kidney transplantation.
Methods: Altogether 53 kidney allograft protocol biopsies from 42 patients on ...
Totaro Pasquale - - 2013
Propeller-like [Fe(4)(L)(2)(dk)(6)] complexes, in which Hdk is a β-diketone and H(3)L is a tripodal alcohol, R-C(CH(2)OH)(3), exhibit tunable magnetic anisotropy barriers and retain their magnetic memory effect when chemically anchored on metal surfaces. Heteronuclear analogues of these M(4) complexes have been sought to afford a library of compounds with different ...
Lee Se Ryeon - - 2013
Nickel(ii) complexes with varying reactive ligands, which were designed to selectively accelerate the initiation rate without influencing the propagation rate in the chain-growth polymerization of π-conjugated monomers, were investigated. Precatalysts with electronically varied reacting groups led to faster initiation rates and narrower molecular weight distributions. Computational studies revealed that the ...
Dean Rebecca K - - 2013
Lithium compounds of tetradentate amino-bis(phenolato)-tetrahydrofuranyl ligands, Li(2)[] () and Li(2)[] () (where [] = 2-tetrahydrofuranyl-N,N-bis(2-methylene-4-methyl-6-tert-butylphenolate), and [] = 2-tetrahydrofuranyl-N,N-bis(2-methylene-4,6-tert-butylphenolate)) were characterized by multinuclear solution NMR and solid-state (6)Li and (7)Li NMR spectroscopy. The proligands, n-propylamino-N,N-bis(2-methylene-4-methyl-6-tert-butylphenol), (H(2)[]) and benzylamino-N,N-bis(2-methylene-4,6-di-tert-amylphenol), H(2)[] were reacted with n-butyllithium in THF to give the related dilithium ...
Degenhardt Karl K Division of Cardiology, Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, - - 2013
Despite many innovative advances in cardiology over the past 50 years, heart disease remains a major killer. The steady progress that continues to be made in diagnostics and therapeutics is offset by the cardiovascular consequences of the growing epidemics of obesity and diabetes. Truly innovative approaches on the horizon have ...
Duman Deniz Güney - - 2013
Saccharomyces boulardii is a probiotic used for the prevention of antibiotic-associated diarrhoea. We aimed to investigate whether S. boulardii could alter the effects of clarithromycin (CLA) and methotrexate (MTX) on oro-caecal intestinal transit and oxidative damage in rats. Rats were divided into two groups receiving a single dose of MTX ...
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