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Mertz Aaron F AF Department of Physics, Yale University, New Haven, CT 06520, - - 2013
Cell-cell and cell-matrix adhesions play essential roles in the function of tissues. There is growing evidence for the importance of cross talk between these two adhesion types, yet little is known about the impact of these interactions on the mechanical coupling of cells to the extracellular matrix (ECM). Here, we ...
Tanioku Chiaki - - 2012
We investigated the thermochromic behavior of polydiacetylenes including the carboxy and 4-carboxyphenyl groups as the side-chain substituents adjacent to the conjugated main-chain, and then the thermal stability and the thermochromism reversibility of the polymers were related to changes in the polymer conformations monitored by IR and Raman spectroscopies, and powder ...
Mrug Sylvie S Department of - - 2013
This study examined age, gender, and racial differences in parental and peer disapproval of alcohol use and in the relationship of these injunctive norms with drinking during adolescence. Participants included 20,239 students ages 11-19 years (average age 14.34; 47% boys; 46% White and 54% Black) from 2 large urban and ...
Migliorati Valentina - - 2012
The structure and dynamics of water in ionic solutions at high pressure have been investigated using a combined approach based on extended X-ray absorption fine structure (EXAFS) spectroscopy and Molecular Dynamics (MD) simulations. Modification of the hydration properties of the Zn(2+) ion induced by a pressure increase from ambient condition ...
Phong Connie - - 2013
Circadian clocks are ubiquitous biological oscillators that coordinate an organism's behavior with the daily cycling of the external environment. To ensure synchronization with the environment, the period of the clock must be maintained near 24 h even as amplitude and phase are altered by input signaling. We show that, in ...
Tan Li Hai - - 2013
Written Chinese as a logographic system was developed over 3,000 y ago. Historically, Chinese children have learned to read by learning to associate the visuo-graphic properties of Chinese characters with lexical meaning, typically through handwriting. In recent years, however, many Chinese children have learned to use electronic communication devices based ...
Ho Man Yee - - 2012
This study adopted a spillover-crossover model to examine the roles of personality and perceived social support as antecedents of the work-family interface among dual-earner couples in China. Married couples (N = 306) from 2 major cities in China (Shanghai and Jinan) completed questionnaires measuring a relationship-oriented personality trait (i.e., family ...
Kleim Birgit - - 2012
Objective: There is a growing body of evidence for the effectiveness of trauma-focused cognitive behavior therapy (TF-CBT) for posttraumatic stress disorder (PTSD), but few studies to date have investigated the mechanisms by which TF-CBT leads to therapeutic change. Models of PTSD suggest that a core treatment mechanism is the change ...
Pillon Nicolas J - - 2012
Skeletal muscles contain resident immune cell populations and their size and type is altered in inflammatory myopathies, endotoxemia or different types of muscle injury/insult. Within tissues, monocytes differentiate into macrophages and polarize to acquire pro- or anti-inflammatory phenotypes. Skeletal muscle macrophages play a fundamental role in repair and pathogen clearance. ...
Pesut Barbara - - 2012
Hospice volunteers play an essential role in the primary care network for end of life. The purpose of this review was to examine the evidence on hospice volunteers published between 2002 and July 2012. An electronic search of PubMed, CINAHL and PsychINFO using controlled vocabulary, and a reference scan, yielded ...
Infurna Frank J - - 2012
Perceived control plays an important role for health across adulthood and old age. However, little is known about the factors that account for such associations and whether changes in control (or control trajectory) uniquely predict major health outcomes over and above mean levels of control. Using data from the nationwide ...
Meleady Rose - - 2012
A robust finding in social dilemmas research is that individual group members are more likely to act cooperatively if they are given the chance to discuss the dilemma with one another. The authors investigated whether imagining a group discussion may represent an effective means of increasing cooperative behavior in the ...
Venn Alexander A - - 2013
Insight into the response of reef corals and other major marine calcifiers to ocean acidification is limited by a lack of knowledge about how seawater pH and carbonate chemistry impact the physiological processes that drive biomineralization. Ocean acidification is proposed to reduce calcification rates in corals by causing declines in ...
Wakamatsu Ei E Division of Immunology, Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA 02115, - - 2013
Costimulatory molecules of the CD28 family on T lymphocytes integrate cues from innate immune system sensors and modulate activation responses in conventional CD4(+) T cells (Tconv) and their FoxP3(+) regulatory counterparts (Treg). To better understand how costimulatory and coinhibitory signals might be integrated, we profiled the changes in gene expression ...
de Ven Bart Van - - 2012
In the present study, the relation between emotional job demands and emotional exhaustion was investigated, as was the moderating role of emotional job resources and emotional support seeking on this relation. We hypothesized a positive lagged effect of emotional job demands on emotional exhaustion, and proposed that this relation is ...
Ramírez Álvarez Elizeth - - 2012
Bifurcations are detected in experiments involving the electrochemical oxidation of copper in phosphoric acid. Ideally, a bifurcation detection protocol requires a model with good qualitative and quantitative prediction capabilities that is also able to reproduce the drift inherent to the electrochemical experiment. A generic protocol for manipulation of nonlinear systems ...
Vajrala Neeraja - - 2013
The ammonia-oxidizing archaea have recently been recognized as a significant component of many microbial communities in the biosphere. Although the overall stoichiometry of archaeal chemoautotrophic growth via ammonia (NH(3)) oxidation to nitrite (NO(2)(-)) is superficially similar to the ammonia-oxidizing bacteria, genome sequence analyses point to a completely unique biochemistry. The ...
Johnson Ray - - 2012
Nessler, Johnson, Bersick, and Friedman (D. Nessler, R. Johnson, Jr., M. Bersick, & D. Friedman, 2006, On why the elderly have normal semantic retrieval but deficient episodic encoding: A study of left inferior frontal ERP activity, NeuroImage, Vol. 30, pp. 299-312) found that, compared with young adults, older adults show ...
Middleton Richard S - - 2012
The Alberta oil sands are a significant source of oil production and greenhouse gas (GHG) emissions, and their importance will grow as the region is poised for decades of growth. We present an integrated framework that simultaneously considers economic and engineering decisions for the capture, transport, and storage of oil ...
Oruganty Krishnadev - - 2013
The protein kinase catalytic domain contains several conserved residues of unknown functions. Here, using a combination of computational and experimental approaches, we show that the function of some of these residues is to maintain the backbone geometry of the active site in a strained conformation. Specifically, we find that the ...
Kim Taegeon - - 2012
In this work, a modified polyol synthesis by adding KBr and by replacing the AgCl with NaCl seed was used to obtain high quality silver nanowires with long aspect ratios with an average length of 13.5µm in length and 62.5nm in diameter. The Ag nanowires suspended in methanol solution after ...
Lee Kyoo-young - - 2013
Temporal and spatial regulation of the replication factory is important for efficient DNA replication. However, the underlying molecular mechanisms are not well understood. Here, we report that ATAD5 regulates the lifespan of replication factories. Reduced expression of ATAD5 extended the lifespan of replication factories by retaining proliferating cell nuclear antigen ...
Liu Guoqiang - - 2012
The main objective of the present study was to completely characterize the metabolites of the triterpenoid saikosaponin a (SSa) in rats. To this aim, we compared the metabolites in the plasma, bile, urine and feces samples following oral and intravenous routes of administration using liquid chromatography-diode array detector coupled with ...
- - 2013
These abstracts are presented here as prepared by the authors. The accuracy and content of each abstract remain the responsibility of the authors. In the identification number above each abstract, OPO designates an Orthopaedic Section poster presentation.J Orthop Sports Phys Ther 2013;43(1):A64-A125.
Farnum Byron H - - 2012
The one-electron reduction of triiodide (I(3)(-)) by a series of reduced ruthenium polypyridyl compounds was studied in an acetonitrile solution at room temperature using the flash-quench technique. Reductive quenching of the metal-to-ligand charge-transfer excited state of [Ru(bpy)(2)(deeb)](2+), [Ru(deeb)(2)(bpy)](2+), or [Ru(deeb)(3)](2+), where bpy is 2,2'-bipyridine and deeb is 4,4'-(CO(2)CH(2)CH(3))(2)-2,2'-bipyridine, by iodide ...
Olhede S C - - 2013
Modulated oscillations are described via their time-varying amplitude and frequency. For multivariate signals, there is structure in the signal beyond this local amplitude and frequency defined for each signal component, in turn describing the commonality of the components. The multivariate structure encodes how the common oscillation is present in each ...
Becker Karin L - - 2012
Abstract Chronic pain is a pervasive and expensive public health problem affecting roughly one-third of the American population. The inability of language to accurately convey pain expressions combined with the social stigmas associated with discussing pain persuade many sufferers to remain silent about their pain. Gender politics and fear of ...
Yang Chunzhang - - 2013
Gaucher disease is caused by mutations of the GBA gene that encodes the lysosomal enzyme glucocerebrosidase (GCase). GBA mutations often result in protein misfolding and premature degradation, but usually exert less effect on catalytic activity. In this study, we identified the molecular mechanism by which histone deacetylase inhibitors increase the ...
Limesand Sean W SW Dept. of Animal Sciences, Univ. of Arizona, 1650 E. Limberlost Dr., Tucson, AZ 85719, USA. - - 2013
In pregnancy complicated by placental insufficiency (PI) and intrauterine growth restriction (IUGR), the fetus near term has reduced basal and glucose-stimulated insulin concentrations and reduced β-cell mass. To determine whether suppression of insulin concentrations and β-cell mass precedes reductions in fetal weight, which would implicate insulin deficiency as a cause ...
Chang Chang-Cheng - - 2012
Purpose The use of microsurgical free flap reconstruction has resulted in improved patient outcomes and survival after head and neck cancer resection. Although postoperative care in an intensive care unit (ICU) for airway management and flap surveillance can increase the success rate, any accompanying neuropsychological problems can potentially affect the outcome.Materials ...
Block Robert W - - 2013
The 113th Congress of the United States begins in January 2013. With each new Congress, there are many changes, not only in the faces of the newly elected, but also in the membership of committees and the staff serving the members. As agendas for the session are set, there is ...
Zhang Wenchao - - 2012
A three-dimensionally ordered macroporous Fe(2)O(3)/Al nanothermite membrane has been prepared with a polystyrene spheres template. The nanothermite, with an enhanced interfacial contact between fuel and oxidizer, outputs 2.83 kJ g(-1) of energy. This is significantly more than has been reported before. This approach, fully compatible with MEMS technology, provides an ...
Zhang Xin - - 2012
How perspective-taking ability changes with age (i.e., whether older adults are better at understanding others' behaviors and intentions and show greater empathy to others or not) is not clear, with prior empirical findings on this phenomenon yielding mixed results. In a series of experiments, we investigated the phenomenon from a ...
Yu Yingfang - - 2012
Objective In this study, we seek to determine independent risk factors of invasive fungal infection (IFI) in neonatal infants.Study Design The medical charts of 5135 neonatal intensive care unit admissions in the past 7 years between January 2004 and December 2010 were reviewed and 45 neonates were found with IFI. Two controls, ...
Scott David - - 2012
Abstract Persons accessing inpatient mental health services generally experience reduced access to and quality of primary health care. The objective of this study was to compare health service utilization and perceptions, and receipt of specified health services, in Australian adults with and without a previous mental illness diagnosis. A cross-sectional ...
Sambridge M - - 2013
Seismologists construct images of the Earth's interior structure using observations, derived from seismograms, collected at the surface. A common approach to such inverse problems is to build a single 'best' Earth model, in some sense. This is despite the fact that the observations by themselves often do not require, or ...
Delker Rebecca K - - 2013
Protein-protein interactions are typically identified by either biochemical purification coupled to mass spectrometry or genetic approaches exemplified by the yeast two-hybrid assay; however, neither assay works well for the identification of cofactors for poorly soluble proteins. Solubility of a poorly soluble protein is thought to increase upon cofactor binding, possibly ...
Shi Junqi - - 2012
In this study, we examined the relations of subordinate political skill with supervisor's dependence on the subordinate and supervisor reward recommendation, as well as mediating (interaction frequency with supervisor) and moderating (supervisor political behavior) variables of these relations. Our theoretical model was tested using data collected from employees in a ...
Tran Hoanh H Department of Cancer Targets, Genentech Inc., South San Francisco, California 94080, USA. - - 2013
The adenomatous polyposis coli (APC) protein functions as a negative regulator of the Wnt signaling pathway. In this capacity, APC forms a "destruction complex" with Axin, CK1α, and GSK3β to foster phosphorylation of the Wnt effector β-catenin earmarking it for Lys-48-linked polyubiquitylation and proteasomal degradation. APC is conjugated with Lys-63-linked ...
Kirsanova Maria A - - 2012
A first clathrate compound with selenium guest atoms, [Ge(46-x)P(x)]Se(8-y)□(y) (x = 15.4(1); y = 0-2.65; □ denotes a vacancy), was synthesized as a single-phase and structurally characterized. It crystallizes in the space group Fm3̅ with the unit cell parameter a varying from 20.310(2) to 20.406(2) Å and corresponding to a ...
Monecke Thomas - - 2013
In eukaryotes, the nucleocytoplasmic transport of macromolecules is mainly mediated by soluble nuclear transport receptors of the karyopherin-β superfamily termed importins and exportins. The highly versatile exportin chromosome region maintenance 1 (CRM1) is essential for nuclear depletion of numerous structurally and functionally unrelated protein and ribonucleoprotein cargoes. CRM1 has been ...
Henry Julie D - - 2012
Age-related difficulties in understanding basic emotional signals are now well established, but less clear is how aging affects theory of mind (ToM), which refers to the understanding of more complex emotions and mental states. A meta-analysis of 23 datasets involving 1462 (790 younger and 672 older) participants was conducted in ...
Cheng Xin R - - 2012
A number of human protein misfolding disorders, including Alzheimer's disease (AD), are closely related to the accumulation of β-sheet-rich amyloid fibrils or aggregates. Neuronal toxicity in AD has been linked to the interactions of amyloid-β (Aβ) with metals, especially Zn2+, Cu2+ and Fe3+, which leads to the production of reactive ...
Rieber Nikolaus - - 2012
Pseudomonas aeruginosa persists in patients with cystic fibrosis (CF) and drives CF lung disease progression. P. aeruginosa potently activates the innate immune system, mainly mediated through pathogen-associated molecular patterns, such as flagellin. However, the host is unable to eradicate this flagellated bacterium efficiently. The underlying immunological mechanisms are incompletely understood. ...
Roberts Brent W - - 2012
Conscientiousness is a personality construct that is a core determinant of health, positive aging, and human capital. A large body of work has contributed to our understanding of this important aspect of personality, but there are multiple conceptual and methodological issues that complicate our understanding of conscientiousness. Toward this end, ...
Fabrizio Cecilia S - - 2012
ABSTRACT: BACKGROUND: This paper describes efforts to generate evidence for community-developed programs to enhance family relationships in the Chinese culture of Hong Kong, within the framework of community-based participatory research (CBPR). METHODS: The CBPR framework was applied to help maximize the development of the intervention and the public health impact ...
Genc Gurkan - - 2012
Objective This study was conducted to evaluate the predictive value of urinary neutrophil gelatinase-associated lipocalin (uNGAL) for acute kidney injury (AKI) among septic preterm infants.Methods Twenty-six very low-birth-weight (VLBW) babies were separated into three groups: group I, healthy preterms; group II, preterms with sepsis but without AKI; group III, preterms with sepsis ...
- - 2013
These abstracts are presented here as prepared by the authors. The accuracy and content of each abstract remain the responsibility of the authors. In the identification number above each abstract, SPL designates a Sports Physical Therapy Section platform presentation.J Orthop Sports Phys Ther 2013;43(1):A43-A63.
Miller Mary Beth - - 2012
Personalized drinking feedback is an evidence-based and increasingly common way of intervening with high-risk college drinking. This article extends an earlier review by Walters and Neighbors (S. T. Walters & C. Neighbors, 2005, Feedback interventions for college alcohol misuse: What, why, and for whom? Addictive Behaviors, 30, 1168-1182) by reviewing ...
Bao Rui R Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, - - 2013
The pH 6 antigen (Psa) of Yersinia pestis consists of fimbriae that bind to two receptors: β1-linked galactosyl residues in glycosphingolipids and the phosphocholine group in phospholipids. Despite the ubiquitous presence of either moiety on the surface of many mammalian cells, Y. pestis appears to prefer interacting with certain types ...
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