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Hentschel Mario - - 2012
We construct chiral plasmonic molecules by assembling two individual chiral centers. Interestingly, depending on the exact arrangement of the centers, all combinations result in a chiral compound with a strong chiral optical response. Furthermore, we demonstrate that the overall circular dichrosim (CD) is determined by the response of the individual ...
Ismail Sahar A - - 2012
Abstract Abstract Background: Vitiligo patients repeatedly experience disinterest from the medical world regarding their disease as it does not cause physical impairment. Several therapeutic options are available for vitiligo management. Objectives: To study vitiligo management strategy in Jeddah, Saudi Arabia (KSA) as indicated by dermatologists and as experienced by patients. ...
Rawolle Monika - - 2012
The degree of filling of titania nanostructures with a solid hole-conducting material is important for the performance of solid-state dye-sensitized solar cells (ssDSSCs). Different ways to infiltrate the hole-conducting polymer poly(3-hexylthiophene) (P3HT) into titania structures, both, granular structures as they are already applied commercially, and tailored sponge nanostructures, are investigated. ...
Goubet Nicolas - - 2012
For self-assembled nanocrystals in 3D superlattices, called supracrystals, the crystalline structure of the metal nanocrystals (either single domain or polycrystallines) or nanocrystallinity, is likely to induce significant changes in the physical properties. Previous studies demonstrated that spontaneous nanocrystallinity segregation takes place in colloidal solution upon self-assembling of 5 nm dodecanethiol-passivated ...
Park Bumsoo - - 2012
To analyze if clinically insignificant prostate cancer (CIPC) is more frequently detected with repeat prostate biopsies, we retrospectively analyzed the records of 2146 men diagnosed with prostate cancer after one or more prostate biopsies. The patients were divided into five groups according to the number of prostate biopsies obtained, e.g. ...
Kulkarni Giridhar U - - 2012
Nowadays, specifying the quality of a transparent conducting electrode (TCE) using a figure of merit (FoM) is considered nearly mandatory. However, not much attention is paid to the local variations in the FoM itself across the large area of the TCE. This calls for the definition of a local FoM ...
Hong Xin - - 2012
The mechanism and origins of selectivities in [Ni(NHC)]-catalyzed intramolecular (5+2) cycloadditions and homo-ene reactions of vinylcyclopropanes (VCPs) and alkynes have been studied using density functional theory. The preferred mechanism involves oxidative alkyne-alkene cyclization to form a metallacyclopentene intermediate, in contrast to cyclopropane cleavage pathway in the reaction with Rh(I) catalysts. ...
Lee Hsiang Ying - - 2012
Purpose: Shock wave lithotripsy (SWL) is a widely utilized treatment for renal and ureteral stones due to its noninvasive approach. Although minor complications arise in most patients, a relatively severe complication, perirenal or subcapsular hematoma, may also occur. We evaluate the possible risk factors for perirenal hematoma following SWL. Material ...
Fischer Christoph Siegfried - - 2012
Three-coordinate complexes (bromo)[4-(2,2-dimethyl-1,3-dioxolan-4-yl)-phenyl](tri-tert-butyl-phosphine)palladium (1) and (bromo){4-[(tetrahydro-2H-pyran-2-yloxy)methyl]phenyl}(tri-tert-butyl-phosphine)palladium (2) were used to initiate Suzuki-Miyaura chain growth polymerization of 7'-bromo-9',9'-dioctyl-fluoren-2'-yl-4,4,5,5,-tetramethyl-[1,3,2]dioxaborolane (3). The polymerization was optionally terminated by end-capping with red-emitting N-(2-ethylhexyl)-1,6-bis(4-tert-octylphenoxy)-9-(4,4,5,5,-tetramethyl-[1,3,2]dioxaborolan-2-yl)-perylene-3,4-dicarboximide. Heterodisubstituted polyfluorenes of adjustable molecular weights between 5 × 10(3) and 1.0 × 10(4) g mol(-1) and narrow molecular weight distribution (M(w)/M(n) ...
Keller Frieder - - 2012
The aim of this retrospective study was to investigate the efficacy of everolimus at our institution and to report incidence and type of side effects in patients who underwent kidney transplantation or hematopoietic stem cell transplantation (HSCT). Electronic medical records were evaluated for 122 patients (76 men and 46 women) ...
Shinohara Naohide - - 2012
Abstract The organ-tissue distribution and clearance of Degussa P25 TiO2 nanoparticles were determined after intravenous administration to rats (0.95 mg/kg-bodyweight) using an inductively coupled plasma sector field mass spectrometer. The detection limits of Ti analysis, 0.54 and 1.4 ng/mL for blood and urine and 0.35-2.0 ng/g tissue for several organ ...
Patel Mishal N - - 2012
Selecting the best targets is a key challenge for drug discovery, and achieving this effectively, efficiently and systematically is particularly important for prioritizing candidates from the sizeable lists of potential therapeutic targets that are now emerging from large-scale multi-omics initiatives, such as those in oncology. Here, we describe an objective, ...
Sypniewski Daniel - - 2012
Despite the fact that the risk of Porcine Endogenous Retroviruses (PERV) infection and propagation in human recipients is extremely low, such an event cannot be completely ruled out, especially in immunosuppressed patients. Therefore, the aim of this study was to analyze the expression of PERVs in vitro in the presence ...
Hau Hans Michael - - 2012
We report our contemporary experiences with renal autotransplantation in patients with complicated renal vascular diseases and/or complex ureteral injuries. Since its first performance, renal autotransplantation has been steadily improved and become a safe and effective procedure. Between 1998 and 2006, 6 renal autotransplantations in 6 patients were performed at the ...
Zhang Rui - - 2012
Purification of nucleic acids from low quantity of bacterial cells in minute volume is im- portant in many clinical and biological applications. We developed a novel microfluidic liquid phase nucleic acid purification chip to selectively isolate DNA or RNA from bacterial cell in the range of 5000 down to a ...
Kim Hyo Won - - 2012
Material surface engineering has attracted great interest in important applications, including electronics, biomedicine, and membranes. More recently, dopamine has been widely exploited in solution-based chemistry to direct facile surface modification. However, unsolved questions remain about the chemical identity of final products, their deposition kinetics and binding mechanism. In particular, the ...
Manna Angelo - - 2012
ABSTRACT: Fractional exhaled nitric oxide (FeNO) is a non invasive method for assessing the inflammatory status of children with airway disease. Different ways to measure FeNO levels are currently available. The possibility of measuring FeNO levels in an office setting even in young children, and the commercial availability of portable ...
Gold Brian - - 2012
Recently, we have identified two strategies for selective transition state (TS) stabilization in catalyst-free azide/alkyne cycloadditions. In particular, the transition states for the formation of both 1,4- and 1,5-isomers can be stabilized via hyperconjugative assistance for the C…N bond formation whereas the 1,5-TS can be stabilized via C-H…X H-bonding interactions. ...
Harada Noboru - - 2012
The surgical management of hepatocellular carcinoma (HCC) in cirrhotic patients with Child-Pugh class B remains controversial. The aim of this study was to compare the results of hepatic resection plus microwave coagulation therapy (MCT) versus living donor liver transplantation (LDLT) for HCC in cirrhotic patients with Child-Pugh class B. Between ...
Sharma Amit - - 2012
Graft-versus-host disease (GVHD) is an uncommon cause of morbidity and mortality after solid organ transplantation that is most likely under-diagnosed. We describe our single center experience with three cases of GVHD diagnosed over a period of 15 years in a total of 2,271 solid organ transplant recipients. We describe three ...
Sebekova Katarina - - 2012
Abstract As a main excretory organ kidney is predisposed to direct/indirect injury. We addressed the potential nephrotoxic effects following expositions of healthy rats to nanoparticles (NPs)-loads relevant to humans in a situation of 100% bioavailability. Up to 4 weeks after administration, a single i.v. bolus of oleate-coated ultra-small superparamagnetic iron ...
Shan Tzu-Ray - - 2012
The dependence of the reaction initiation mechanism of pentaerythritol tetranitrate (PETN) on shock orientation and shock strength is investigated with molecular dynamics simulations using a reactive force field and the multiscale shock technique. In the simulations, a single crystal of PETN is shocked along [110], [001], and [100] orientations with ...
Al-Jedai Ahmed - - 2012
Kidney transplantation in allosensitized recipients has recently increased. Studies performing cost analysis of desensitization protocols are scarce. We performed an actual cost comparison between kidney transplantation following desensitization and maintenance hemodialysis. Group A (n=35) consisted of allosensitized recipients who underwent desensitization using immunoadsorption and/or plasmapheresis, intravenous immunoglobulin and anti-CD20 antibody ...
Vuojola Johanna - - 2012
The study of biomolecular interactions is at the heart of biomedical research. Fluorescence and Förster resonance energy-transfer (FRET) are potent and versatile tools in studying these interactions. Fluorescent proteins enable genetic encoding which facilitates their use in recombinant protein and in vivo applications. To eliminate the autofluorescence background encountered in ...
Wu Shao-Chun - - 2012
After liver transplantation (LT), re-exploration of the abdomen to check for bleeding is sometime required. Our study aimed to identify the predictive factors by analysis of preoperative and intraoperative presentations that may impact the re-exploration for hemostasis. We selected 522 consecutive recipients from the Liver Transplant Program database and medical ...
von Boehmer Harald - - 2012
Forkhead box P3 (FOXP3)-expressing regulatory T (T(Reg)) cells have a pivotal role in the regulation of immune responses and in the maintenance of immunological self-tolerance. These cells have emerged as attractive targets for strategies that allow the steering of immune responses in desired directions - arming the immune system to ...
La Vignera Sandro - - 2012
Although alcohol is widely used, its impact on the male reproductive function is still controversial. Over the years, many studies have investigated the effects of alcohol consumption on sperm parameters and male infertility. This article reviews the main preclinical and clinical evidences. Studies conducted on the experimental animal have shown ...
Halawa Ahmed - - 2012
At present, first and second kidney transplantation have established surgical techniques with few variations between surgeons. They also are considered the best renal replacement therapy for patients with end stage renal disease. Both offer better quality of life and longer survival compared to dialysis. However the third and fourth transplants ...
Pacholczyk Marek - - 2012
Currently, HCV (hepatitis C virus) cirrhosis is one of the most common indications for liver transplantation (LTx) in Europe and North America among adults. Very early after LTx, histological examinations of liver biopsies in a group of HCV-positive recipients show important differences compared to other indications for transplantation. We described ...
Kociszewska-Najman Bożena - - 2012
Pregnancies in graft recipients are associated with increased risk of a number of pathologies. The aim of the study was to analyze results of brain and abdominal ultrasonography and echocardiography (ECHO) in neonates born to liver (LTx) or renal recipients (RTx). The study group consisted of 82 neonates born to ...
Frantsuzov Pavel - - 2012
A variety of optically active nanoscale objects show extremely long correlations in the fluctuations of fluorescence intensity (blinking). Here we performed a systematic study to quantitatively estimate the power spectral density (PSD) of the fluorescence trajectories of colloidal and self-assembled quantum dots (QDs), nanorods (NRs), nanowires (NWs), and organic molecules. ...
Yang Xiaoli - - 2012
Living donor liver transplantation (LDLT) is a very successful procedure that develops liver resources in case of worldwide shortages. As the technology has developed so much in the past 2 decades, LDLT has the same good prognosis as DDLT. However, LDLT still has lots of ethical & technical problems. It ...
Ottaway Josh - - 2012
An essential part to calibration is establishing the analyte calibration reference samples. These samples must characterize the sample matrix and measurement conditions (chemical, physical, instrumental, and environmental) of any sample to be predicted. Calibration usually requires measuring spectra for numerous reference samples in addition to determining the corresponding analyte reference ...
Hwang Ee Taek - - 2012
In the present study, we report on enzyme-assisted formation of biomineralized amorphous calcium phosphate nanocomposites (ACP-NCs). About 100-200 nm sizes of the spherical porous enzyme-assisted ACP-NCs were successfully synthesized via double reverse microemulsion, but no ACP-NCs formed without the enzyme. It is believed that the enzyme was used as an ...
Ortiz Jorge - - 2012
A recent review reported that recipient HCV infection had no significant impact on acute rejection rates or patient survival in SPKT but the utilization of HCV(+) organs was negligible. Using the UNOS database, we sought to determine utilization rates for HCV(+) allografts in Simultaneous Pancreas-Kidney Transplantation (SPKT. The Organ Procurement ...
Zhang Dian-cai DC Department of General Surgery, The First Affiliated Hospital, Nanjing Medical University, - - 2013
Gemcitabine has been increasingly prescribed for the treatment of gallbladder cancer. However, the response rate is low. The aim of this study is to determine whether icariin, a flavonoid isolated from Epimedi herba, could potentiate the antitumor activity of gemcitabine in gallbladder cancer. Human gallbladder carcinoma cell lines GBC-SD and ...
Fabre Bruno - - 2012
The deposition of gold and platinum nanoparticles (NPs) on hydrogen-terminated Si(100) (Si(100)-H) surfaces has been performed by galvanic displacement using fluoride-free sub-mM metallic salt solutions. The scanning electron microscopy (SEM) images showed the formation of oblate hemispherical NPs, with an average diameter of ca. 40 nm and an average height ...
Chopra Sascha S - - 2012
The objective was to evaluate contrast enhanced ultrasound (CEUS) based cholangiography compared to conventional radiography as a reference method in patients after liver transplantation. Contrast agents were administered through T-tubes, which were placed during the operation. Twelve patients with side-to-side choledocho-choledochostomy and standardized intraoperative T-tube placement were investigated on the ...
Sułkowska Katarzyna - - 2012
Everolimus is a derivative of sirolimus, and is considered to be free of the latter's pulmonary toxicity. Recently, a few cases of everolimus-induced lung injury have been reported. Early recognition of drug-induced lung disease is important because it can be reversed if appropriate therapy is instituted soon after the onset ...
Iwamura Munetaka - - 2012
Structural dynamics involving tight Au-Au bond formation of excited-state oligomers [Au(CN)(2)(-)](n) was studied using picosecond/femtosecond time-resolved emission and absorption spectroscopy. With selective excitation of the trimer ([Au(CN)(2)(-)](3)) in aqueous solutions, transient absorption due to the excited-state trimer was observed around 600 nm. This transient exhibited a significant intensity increase (τ ...
Celik Orcun - - 2012
The higher frequency of varicocele in men with infertility has drawn attention and resulted in increased research at the molecular level towards treatments. The aim of this study was to investigate the role of tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) and its receptors in varicocele-induced testicular dysfunction in an ...
Alexander Cameron - - 2012
We wanted to bring to your attention some errors in the report published in your journal by Michielsen and Coomans(1). In Table no. 4, on page 1336, the reported data for Tefekli and colleagues (2) and Bhansali and colleagues (3) does not match the data from their published reports. Michielsen ...
Mustard Thomas J L - - 2012
Density functional theory computations of the Cu-catalyzed ring expansion of vinyloxiranes is mediated by a traceless dual Cu(I)-catalyst mechanism. Overall, the reaction involves a monomeric Cu(I)-catalyst, but a single key step, the Cu migration, requires two Cu(I)-catalysts for the transformation. This dual-Cu step is found to be a true two ...
Ametamey Simon M - - 2012
The folate receptor (FR) has been identified as a valuable target for imaging of cancer and activated macrophages, involved in inflammatory and autoimmune diseases via positron emission tomography (PET). Therefore, conjugates of folic acid have been synthesized by coupling of a radiolabeled prosthetic group to the glutamate part of folic ...
Carter J F - - 2012
The need for inter-laboratory comparability is crucial to facilitate the globalisation of scientific networks and the development of international databases to support scientific and criminal investigations. This article considers what lessons can be learned from a series of inter-laboratory comparison exercises organised by the Forensic Isotope Ratio Mass Spectrometry (FIRMS) ...
Bollati Irene - - 2012
Glacial environments are considered geomorphosites because they exhibit all of the features that characterise sites of geomorphological interest. The Miage Glacier, in particular, is the most important debris-covered glacier of the Italian Alps, and it has been extensively studied since the 18th century because of its scientific features. In this ...
Xue Yijun - - 2013
Cancerous inhibitor of protein phosphatase 2A (CIP2A) is a recently identified human oncoprotein that stabilizes the c-MYC protein. Herein, we aimed to investigate its expression pattern, clinical significance, and biological function in urothelial cell carcinoma (UCC) of the bladder. CIP2A expression was examined in 20 fresh bladder UCC tissues and ...
Lévy Véhel Pierre-Emmanuel - - 2012
We consider a simple multi-IV model for drug concentration in the case of poor patient compliance. The model is a stochastic one, and is thus able to take into account an irregular drug intake schedule. Under some assumptions, we study features of the drug concentration relevant for practical purposes such ...
Cora Tulin - - 2012
Myocardial infarction (MI), which is the most important manifestation of coronary artery disease, is the leading cause of morbidity and mortality in the world. Glutathione S transferases (GSTs) are enzymes responsible for the metabolism of numerous xenobiotics and are known to be polymorphic in humans. We investigated the association between ...
Pyziel Anna M - - 2012
Over a 4-year period, we analyzed 128 fecal samples from free-living elk (Alces alces L., 1758) to determine the prevalence of Eimeria infections and identify the species present. Two eimerian species were isolated including Eimeria alces and a morphotype resembling Eimeria catubrina. Overall, two samples from 128 samples collected were ...
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