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Levi Susannah V - - 2012
PURPOSE: To investigate how differences in language ability relate to differences in processing talker information in the native language and an unfamiliar language by comparing performance for different ages and for groups with impaired language. METHOD: Three groups of native-English listeners with typical language development (TLD) (ages 7-9, ages 10-12, ...
Wang Zhen-Gang - - 2012
Templated synthesis has been considered as an efficient approach to produce polyaniline (PANI) nanostructures. The features of DNA molecules enable DNA template to be an intriguing template for fabrication of emeraldine PANI. In this work, we assembled HRP-mimicking DNAzyme with different artificial DNA nanostructures, aiming to manipulate the molecular structures ...
Takahashi Yasuhiro - - 2012
An 83-year-old woman with Sjögren syndrome underwent insertion of large punctal plugs in the right upper and lower puncti. Nine months later, she presented with upper canaliculitis, although the plugs were not found in the puncti. Dacryoendoscopic examination revealed punctal plug migration, granulation, and a large amount of debris in ...
Nwanyanwu Kristen Harris - - 2012
OBJECTIVEIdentifying individuals most at risk for diabetic retinopathy progression and intervening early can limit vision loss and reduce the costs associated with managing more advanced disease. The purpose of this study was to identify factors associated with progression from nonproliferative diabetic retinopathy (NPDR) to proliferative diabetic retinopathy (PDR).RESEARCH DESIGN AND ...
Cheng Shao-Yi - - 2012
OBJECTIVE: The effectiveness of inpatient palliative care units, a complex intervention, is challenging to evaluate due to methodological and practical difficulties. We conducted a study to evaluate providers' perceived effectiveness of one such unit. METHODS: A non-concurrent, prospective, controlled study using the Audit Scale for good death services as an ...
Sibille Romain - - 2012
A new hydroxythiophenedicarboxylate metal-organic framework based on Mn(II) cations has been obtained by an aqueous two-step procedure including hydrothermal treatment. The structure of Mn(3)(OH)(2)(C(6)H(2)O(4)S)(2) has been determined ab initio from synchrotron X-ray powder diffraction data and consists of infinite inorganic ribbons which are interlinked by 2,5-thiophenedicarboxylate (tdc) molecules (monoclinic, space ...
Burston Adam S - - 2012
Moral distress has been widely reviewed across many care contexts and among a range of disciplines. Interest in this area has produced a plethora of studies, commentary and critique. An overview of the literature around moral distress reveals a commonality about factors contributing to moral distress, the attendant outcomes of ...
Kramer Frank - - 2012
MOTIVATION: Biological pathway data, stored in structured databases, is a useful source of knowledge for a wide range of bioinformatics algorithms and tools. The Biological Pathway Exchange (BioPAX) language has been established as a standard to store and annotate pathway information. However, use of this data within statistical analyses can ...
Bongaerts Brenda W C - - 2012
OBJECTIVEDistal sensorimotor polyneuropathy (DSPN) is a severe complication of type 2 diabetes. This study aimed to assess the prevalence of unawareness of DSPN in prediabetes and diabetes in a sample of the older population of Augsburg, Germany.RESEARCH DESIGN AND METHODSGlucose tolerance status was determined in 61- to 82-year-old participants of ...
Cordes Martin - - 2012
Objectives: The O-AFP can be used as a rater-administered inventory (RAI) and as a self-report scale (SRS). The study analyses the relations between these versions.Methods: O-AFP-scales for working abilities and work complexity and SCL-90-R data of 88 vocational therapy patients (psychiatric clinic, PC; addiction clinic, AC).Results: Only few significant correlations ...
Ilivitzki Anat - - 2012
INTRODUCTION:: Traditionally in pediatric oncology, biopsies were incisional, with a recent alternative of percutaneous imaging-guided biopsies. In our department, ultrasound (US)-guided core biopsy is the first choice for tissue diagnosis in the pediatric population. We retrospectively reviewed our experience and assessed the accuracy rate, safety, and availability of the procedure. ...
Egli Adrian - - 2012
BACKGROUND: Data on how different immunosuppressive drugs affect cytomegalovirus (CMV)-specific T-cell responses may help guide more rational modification of immunosuppression in patients with CMV replication. We assessed the in vitro effects of individual standard and novel immunosuppressive drugs on a broad range of CMV-specific T-cell responses. METHODS: Peripheral blood mononuclear ...
Rojek Aleksandra - - 2012
Aquaporin 11 (AQP11) is a protein channel expressed intracellularly in multiple organs, yet its physiological function is unclear. Aqp11 knockout (KO) mice die early due to malfunction of the kidney, a result of hydropic degeneration of proximal tubule cells. Here we report the generation of liver-specific Aqp11 KO mice, allowing ...
Liu Dandan - - 2012
The title compound was synthesized mainly by palladium catalytic coupling, cyclopropyl ring-opening rearrangement, epoxidation, Swern oxidation, demethanol reactions, and selective reduction. This synthesis was achieved in 16 steps with 9.7% overall yield. Unfortunately, the published spectroscopic data do not match with those of our synthetic compound.
Plumb Allison M - - 2012
PURPOSE: To examine the vocalizations of children with autism spectrum disorder (ASD) in the second year of life and their relationship to other areas of development. METHOD: Vocalizations were examined in 125 children between 18 and 24 months of age: 50 later diagnosed with ASD; 25 with developmental delays (DD) ...
Otis-Green Shirley - - 2012
Abstract Intraperitoneal chemotherapy poses both potential benefits as a cancer treatment and negative consequences on patient and family quality of life. The profound multi-dimensional quality of life impact of intraperitoneal (IP) chemotherapy upon women with advanced ovarian cancer makes the early integration of palliative care particularly important for this population. ...
Held Kristin - - 2012
BACKGROUND:: Oral chemotherapy is commonly administered in the home; however, there may be harmful effects on healthy individuals who handle these medications. Caregivers of pediatric patients were surveyed to establish educational needs for safe handling of oral chemotherapy agents. METHODS:: An 11-question self-report survey was developed to characterize handling practices ...
Guillon Michel - - 2012
ABSTRACT:: The current literature review was intended to investigate whether the use of silicone hydrogel contact lenses has resulted in improved comfort compared with that of hydrogel contact lenses when both are used for daily wear. The conclusion reached is that silicone hydrogel contact lenses, which were initially developed to ...
Babic Tanja - - 2012
Copper plays an essential role in the function and development of the central nervous system and the exocrine pancreas. Dietary copper limitation is known to result in a non-inflammatory atrophy of pancreatic acinar tissue. Our recent studies have suggested that vagal motoneurons regulate pancreatic exocrine secretion (PES) by activating selective ...
Lind Evan F - - 2012
Recent studies have begun to define the role of micro-RNAs in regulating the immune response. Micro-RNA155 (mir-155) has been shown to play a role in germinal center formation, T cell inflammation, and regulatory T cell development. In this study, we evaluated the role of mir-155 in cytotoxic T cell function. ...
Laskowska Marzena - - 2012
Objective. The aim of our study was to investigate the association between homocysteine and asymmetric dimethylarginine in preeclamptic women with and without intrauterine growth restriction compared with normal healthy uncomplicated pregnancies and normotensive pregnancies complicated by idiopathic isolated intrauterine fetal growth restriction. Methods. The maternal serum homocysteine and asymmetric dimethylarginine ...
Nys Julie - - 2012
PURPOSE: Counting and exact arithmetic rely on language-based representations, whereas number comparison and approximate arithmetic involve approximate quantity-based representations which are available early in life, before the first stages of language acquisition. The objective of this study is to examine the impact of language abilities on the later development of ...
Sjaarda Lindsey - - 2012
OBJECTIVETo compare β-cell function relative to insulin sensitivity, disposition index (DI), calculated from two clamps (2cDI, insulin sensitivity from the hyperinsulinemic-euglycemic clamp and first-phase insulin from the hyperglycemic clamp) with the DI calculated from the hyperglycemic clamp alone (hcDI).RESEARCH DESIGN AND METHODSComplete data from hyperglycemic and hyperinsulinemic-euglycemic clamps were available ...
De Rosa Michael - - 2012
Protonation of 3-aminopyrrole at C-2 gave the sigma-complex 1H-pyrrol-3(2H)-iminium cation, whereas, protonation at the exo-amino group gave its 1H-pyrrol-3-aminium tautomer. Both tautomers were isolated as their respective tetrakis(pentafluorophenyl) borate salt-an example of desmotropy. In solution the NH3-tautomer was favored in hydrogen-bonding solvents, and the CH2-tautomer in CH2Cl2. A combination of ...
Klein Rodrigo - - 2012
BACKGROUND: The discard rate of kidneys recovered from deceased donors with acute renal failure (ARF) is higher compared with those without ARF mainly due to the uncertainty regarding short-term and long-term outcomes. METHODS: We retrospectively analyzed 1-year patient, graft, and rejection-free survivals and renal function of transplantations performed with kidneys ...
Kamran Sophia C - - 2012
Context:Thyroid nodule size is routinely measured, although its impact on thyroid cancer risk is unclear.Objective:Our objective was to evaluate the association of nodule size upon cancer risk.Design, Setting, and Patients:We conducted a retrospective cohort analysis at an academic hospital with 4955 consecutive patients evaluated between 1995 and 2009.Intervention:Ultrasound and ultrasound-guided ...
Mueller Jana A - - 2012
PURPOSE: To synthesize quantitative findings concerning measures of executive function (EF) in adults with acquired brain injury (ABI). Methods Electronic databases were searched for studies of EF assessments in adults with ABI that reported any of three values: likelihood ratios (LR); standardized group mean comparisons (d); or correlations (r) among ...
Williams David E - - 2012
The histone lysine monomethyltransferase SETD8 is an epigenetic regulator of cell cycle progression. Nahuoic acid A (1), a polyketide produced in culture by a Streptomyces sp. obtained from a tropical marine sediment, is the first known selective SAM-competitive inhibitor of SETD8. The structure of nahuoic acid A (1) has been ...
Kim Jang-Young - - 2012
OBJECTIVEIncreased adiponectin levels may play a protective role in the development of metabolic abnormalities, but prospective studies of the predictive value of serum adiponectin to identify individuals at high risk of new-onset metabolic syndrome are lacking. We investigated whether serum adiponectin predicts incident cases of the metabolic syndrome in a ...
McGrady Michael G - - 2012
ABSTRACT: BACKGROUND: To determine the association between social deprivation and the prevalence of caries (including caries lesions restricted to enamel) and enamel fluorosis in areas that are served by either fluoridated or non-fluoridated drinking water using clinical scoring, remote blinded, photographic scoring for caries and fluorosis. The study also aimed ...
Soriano Ronald B - - 2012
A series of novel rock-salt-type Pb(m)Sb(2n)Te(m+3n) nanocrystals (m = 2, 3, 4, 6, 8, and 10; n = 1 and 2) were successfully prepared using a colloidal synthesis route. These materials are stable only on the nanoscale and have no bulk analogues. Elemental compositions were determined using scanning transmission electron ...
Jiang Yimei - - 2012
Abstract Objective: To report the feasibility of laparoscopic resection with intraoperative radiotherapy for local advanced rectal cancer in an Asian man. Patient and Methods: A 55-year-old man with adenocarcinoma of the rectum presented at Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China. The tumor, with a size of ...
Longest P Worth - - 2012
Abstract Background: Previous studies have demonstrated the delivery of pharmaceutical aerosols through nasal cannula and the feasibility of enhanced condensational growth (ECG) with a nasal interface. The objectives of this study were to develop a device for generating submicrometer aerosols with minimal depositional loss in the formation process and to ...
Celik Mehmet Ali - - 2012
N-Heterocyclic carbene ligand SIDipp (SIDipp = 1,3-bis(2,6-diisopropylphenyl)imidazolin-2-ylidene) and trimesitylphosphine ligand have been used in the synthesis of gold(I) cyanide, t-butylisocyanide, and cyclooctyne complexes (SIDipp)Au(CN) (3), (Mes(3)P)Au(CN) (4), [(Mes(3)P)(2)Au][Au(CN)(2)] (5), [(SIDipp)Au(CN(t)Bu)][SbF(6)] ([6][SbF(6)]), [(SIDipp)Au(cyclooctyne)][SbF(6)] ([8][SbF(6)]), and [(Mes(3)P)Au(cyclooctyne)][SbF(6)] ([9][SbF(6)]). A detailed computational study has been carried out on these and the related gold(I) ...
Osorio-Fuentealba Cesar - - 2012
Skeletal muscle glucose uptake in response to exercise is preserved in insulin-resistant conditions, but the signals involved are debated. ATP is released from skeletal muscle by contractile activity and can autocrinely signal through purinergic receptors, and we hypothesized it may influence glucose uptake. Electrical stimulation, ATP, and insulin each increased ...
Zhang Xi - - 2012
Both fibril and spherical polyaniline (PANI) nanostructures have successfully served as nanofillers for obtaining epoxy resin polymer nanocomposites (PNCs). The effects of nanofiller morphology and loading level on the mechanical properties, rheological behaviors, thermal stability, flame retardancy, electrical conductivity and dielectric properties were systematically studied. The introduction of the PANI ...
Engel de Abreu Pascale M J - - 2012
PURPOSE: This study explored the impact of test language and cultural status on vocabulary and working memory performance in multilingual language minority children. METHOD: Twenty 7-year-old Portuguese-speaking immigrant children living in Luxembourg completed several assessments of first- and second-language vocabulary (comprehension and production), executive-loaded working memory (counting recall and backward ...
Besch Dorothea - - 2012
We report on two prepubescent girls with visual loss due to idiopathic intracranial hypertension (IIH), or pseudotumor cerebri, both treated with recombinant human growth hormone for growth failure. The interval from starting hormone therapy to diagnosis of IIH was 3 and 18 months, respectively. Both girls did not complain of ...
Brønstad Eivind - - 2012
Abstract Objective: The aim of this study was to investigate the effects of moderate continuous training (MCT) and high intensity aerobic interval training (AIT) on systolic ventricular function and aerobic capacity in COPD patients. Methods: Seventeen patients with COPD (64 ± 8 years, 12 men) with FEV(1) of 52.8 ± 11% ...
Hata Yoshinobu - - 2012
A ciliated muconodular papillary tumor has been reported to be a peripheral low-grade malignant tumor, consisting of ciliated columnar cells and goblet cells with basaloid cell proliferation. Although ciliated muconodular papillary tumors have not yet been classified according to the World Health Organization classification, they can pose diagnostic and therapeutic ...
Iizuka Daisuke - - 2012
Aberrant expression of microRNAs (miRNAs) is frequently associated with a variety of cancers, including breast cancer. We and others have demonstrated that radiation-induced rat mammary cancer exhibits a characteristic gene expression profile and a random increase in aberrant DNA copy number, however, the role of aberrant miRNA expression is unclear. ...
Fromentin Claire - - 2012
Dietary proteins are believed to participate significantly in maintaining blood glucose levels, but their contribution to endogenous glucose production (EGP) remains unclear. We investigated this question using multiple stable isotopes. After overnight fasting, eight healthy volunteers received an intravenous infusion of [6,6-(2)H(2)]-glucose. Two hours later, they ingested four eggs containing ...
Bandyopadhyay Anindita - - 2012
In order to accommodate the physiologically incompatible processes of photosynthesis and nitrogen fixation within the same cell, unicellular nitrogen fixing cyanobacteria have to maintain a dynamic metabolic profile in the light as well as the dark phase of a diel cycle. The transition from the photosynthetic to the nitrogen-fixing phase ...
Searl Jeff - - 2012
PURPOSE: This study compared articulatory contact pressure (ACP), oral air pressure (Po) and speech acoustics for conversational versus clear speech. The relationship of these measures to listener perception also was assessed. METHOD: Twelve adults with normal speech produced monosyllables in a phrase using conversational and clear speech. Target phonemes were ...
Manjunath G - - 2012
The echo state property is a key for the design and training of recurrent neural networks within the paradigm of reservoir computing. In intuitive terms, this is a passivity condition: a network having this property, when driven by an input signal, will become entrained by the input and develop an ...
Yang S-Y - - 2012
BACKGROUND: /st>The aim of this prospective trial was to investigate the ability of pulse pressure variation (PPV) and corrected flow time (FTc) to predict fluid responsiveness in the prone position. METHODS: /st>Forty-four patients undergoing lumbar spine surgery in the prone position on a Wilson frame were prospectively studied. PPV and ...
Ferrer Rebecca A - - 2012
Worry and risk perceptions are generally found to be independently associated with health-promoting behaviors, although it is unknown whether they interact in ways that potentially dampen the effect of either construct on behavior. In this hypothesis-generating study, cancer-related worry and risk perception, and their interaction, were used to predict odds ...
Kellerman Donald J - - 2012
Abstract Background: MAP0004 is an investigational orally inhaled dihydroergotamine (DHE) delivered via a TEMPO(®) metered dose inhaler that was effective in the acute treatment of migraine in a large Phase 3 trial. Rapid and consistent absorption of DHE is important for efficacy in the acute treatment of migraine. Methods: The ...
Kuroda Keiji - - 2012
The actions of glucocorticoids at the feto-maternal interface are not well understood. Here, we show that decidualization of human endometrial stromal cells (HESCs) in response to progesterone and cAMP signaling is associated with a strong induction of 11β-hydroxysteroid dehydrogenase type 1 (11βHSD1) expression and enzyme activity. Decidualization also triggered a ...
Yang Mengliu - - 2012
OBJECTIVEZinc-α(2)-glycoprotein (ZAG) has been proposed to play a role in the pathogenesis of insulin resistance. Previous studies in humans and in rodents have produced conflicting results regarding the link between ZAG and insulin resistance. The objective of this study was to examine the relationships between ZAG and insulin resistance in ...
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