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Results 401 - 450 of 2635
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Unterbrink Thomas - - 2012
PURPOSE: In order to evaluate a manual-based group program for teachers aiming at strengthening mental health, we examined (1) whether the teachers interested in participating differ from their colleagues without interest and (2) whether there is evidence of subgroups benefiting more than others among those who participated. METHODS: Out of ...
Haasl Ryan J RJ Laboratory of Genetics, University of Wisconsin, Madison, WI, - - 2013
We use genotype data from the Marshfield Clinical Research Foundation Personalized Medicine Research Project to investigate genetic similarity and divergence between Europeans and the sampled population of European Americans in Central Wisconsin, USA. To infer recent genetic ancestry of the sampled Wisconsinites, we train support vector machines (SVMs) on the ...
Leite Hianna Almeida Câmara - - 2012
Clonal genotypes resistant to fungal diseases are an important component of the cocoa production system in southeastern Bahia state (Brazil), so that technologies for faster production of stronger and healthier plantlets are highly desirable. In this study, the effects of inoculated bacterial endophytes isolated from healthy adult cacao plants on ...
Lao T T - - 2012
SUMMARY We examined the impact of the neonatal hepatitis B immunization programme, first provided to all neonates born to mothers screened positive for hepatitis B surface antigen (HBsAg) in late 1983, on the age-specific prevalence of HBsAg carriage in teenage mothers managed in 1998-2008. HBsAg carriage was found in 2·5%, ...
Tanaka Yoshiya - - 2012
Rheumatoid arthritis (RA) is a representative autoimmune disease characterized by chronic and destructive inflammatory synovitis. The multiple cytokines play pivotal roles in RA pathogenesis by inducing intracellular signaling, and members of the Janus kinase (JAK) family are essential for such signal transduction. An orally available JAK3 inhibitor, tofacitinib, has been ...
Domínguez-García Moralba M Department of Chemistry, University of Puerto Rico, PO Box 9019, Mayagüez, PR 00681, - - 2013
Three new water-soluble tungstenocene derivatives were synthesized and characterized using 3-hydroxy-4-pyrone ligands, which provide aqueous stability to the complexes. The antiproliferative activities of the complexes on HT-29 colon cancer and MCF-7 breast cancer cell lines were evaluated by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay and showed the new tungstenocene derivatives have higher antiproliferative ...
Fischer Steven L - - 2012
Accurate estimation of occupational performance capability facilitates better job (re-) design by informing workplace parties about the potential mismatches between job demands and the capability of their labour force. However, estimating occupational performance requires consideration of multiple factors that may govern capacity. In this paper, a novel model is described ...
Potegal Michael - - 2012
Revenge appears among a "suite" of social interactions that includes competition, alliance building (a prerequisite for tribal revenge raids), and so forth. Rather than a modular "system" directly reflecting evolutionary fitness constraints, revenge may be (another) social cost-benefit calculation involving potential or actual aggression and proximately controlled by individual personality ...
El Bestawy Ebtesam - - 2012
The present study aimed to overcome the toxicity of the heavy metals load, discharged with the industrial effluents into Alexandria sewerage network, on the activated sludge treatment system through effective acclimation for organic matter and heavy metals removal. Optimization and/or acclimatization of the activated sludge process in the presence of ...
Phan Phuong L - - 2013
To investigate the basic spatio-temporal gait characteristics of people with stroke whilst walking on sloped and level terrain, and to compare this performance to healthy matched adults. Fifteen community dwelling people with stroke who walked with a hemiplegic gait and a reference group of 15 adults without impairments matched for ...
Thaipisuttikul Papan P Comprehensive Center on Brain Aging, Alzheimer Disease Center, New York University Langone Medical Center, New York, NY, - - 2013
Capgras syndrome is characterized by the recurrent, transient belief that a person has been replaced by an identical imposter. We reviewed clinical characteristics of Dementia with Lewy Bodies (DLB) patients with Capgras syndrome compared to those without Capgras. We identified 55 consecutive DLB patients (11 cases with Capgras syndrome (DLB-C) ...
de Garibay Gorka Ruiz GR Laboratorio de Oncología Molecular, Instituto de Investigación Sanitaria San Carlos, Madrid, - - 2013
Fanconi anemia is a genetically heterogeneous autosomal recessive disorder characterized by development abnormalities, bone marrow failure, and childhood cancers. Compelling evidence indicates a common genetic basis for FA and breast/ovarian cancer susceptibility. Recently, biallelic germ-line mutations in SLX4 have been demonstrated to cause a previously unknown FA subtype (FA-P). We ...
Watanabe Kaori - - 2012
OBJECTIVES: To investigate the clinical characteristics and risk factors of Pneumocystis jirovecii pneumonia (PCP) in rheumatoid arthritis (RA) patients treated with adalimumab. METHODS: We conducted a multicenter, retrospective, case-control study to compare RA patients treated with adalimumab with and without PCP. Data from 17 RA patients who were diagnosed with ...
Schindler Amrei - - 2012
Background: The efficacy of CBT for unipolar depressive disorders is well established, yet not all patients improve or tolerate treatment. Aims: To identify factors associated with symptomatic outcome, response, and drop-out in depressive patients under naturalistic CBT. Method: 193 patients with major depression or dysthymia were tested. Sociodemographic and clinical ...
Felicia Leona J - - 2012
Oil based nanofluid containing surfactant capped magnetite nanoparticles are synthesized by simple co-precipitation approach and their magneto-rheological properties are studied for different magnetic field strengths and volume fractions. We observe a distinct 'plateau-like region' in the shear thinning viscosity curve, under an external magnetic field, possibly due to a peculiar ...
Liu Xiangjun - - 2012
In this paper, we describe a turn-on fluorescent probe for Zn(2+) and Cd(2+) ion detection and discrimination. This probe, N'-bis-(N,N-di-(2-pyridylmethyl)-ethane-1,2-diamine)-perylene-3,4,9,10-tetracarboxylic-diimide (PDI-DIDPA), exhibits very low fluorescence at pH above 6.0 due to the photo-induced electron transfer (PET) process from 2-pyridylmethyl-amine (DPA) to perylene tetracarboxylic diimide (PDI). Zn(2+) and Cd(2+) can chelate ...
Mukerji N - - 2012
Background. Maintenance of on-call referrals databases is on the rise in neurosurgical units across the UK and helps provide data to estimate workload. We hypothesize that these databases underestimate the workload and propose the use of the number of telephone calls to the on-call registrar as an easily obtainable and ...
He Hongzhi - - 2012
Individual and joint toxicity of three chloroacetanilide herbicides to a freshwater cladoceran were studied. The 48 h-LC(50) values of alachlor, acetochlor and butachlor to Daphnia carinata Dc42 were 11.1, 11.8 and 3.45 mg L(-1), respectively. The toxicity was significantly (p < 0.05) related to hydrophobicity. The additive indexes of binary mixtures of three herbicides were ...
Veyrie Nicolas - - 2012
BACKGROUND: Because of the lack of published data and the relative rarity of lateral incisional hernia (LIH), their repair remains a major challenge for surgeons. The aim of the present study was to evaluate the outcome of LIH treated by the retromuscular approach (RMA) with a polyester standard mesh. METHODS: ...
Edward Raja Chellaiah - - 2012
Boron is an essential micronutrient for plants, but can above certain concentrations be toxic to living organisms. A major environmental concern is the removal of boron from contaminated water and fly ash. For this purpose, the samples were collected from a fly ash dumping site, Nagasaki prefecture, Japan. The chemical ...
Burke Brian - - 2012
The nuclear lamina is an important structural determinant for the nuclear envelope as a whole, attaching chromatin domains to the nuclear periphery and localizing some nuclear envelope proteins. The major components of the lamina are the A-type and B-type lamins, which are members of the intermediate filament protein family. Whereas ...
Salomon Carmela - - 2012
In light of the high number of people discontinuing antipsychotics each year, it is essential that nurses develop a robust understanding of all aspects of the discontinuation experience. While there is a large body of published work documenting post-discontinuation relapse rates, less is known about other aspects of the discontinuation ...
Räisänen Sari - - 2012
INTRODUCTION AND HYPOTHESIS: Obstetric anal sphincter injury (OASIS) following birth may have serious, long-term effects on affected women, including fecal incontinence, despite primary repair. METHODS: This was a retrospective population-based register study. Women with OASIS grouped by order of vaginal delivery and prior cesarean section (CS) were compared separately with ...
Xu Huiping - - 2012
Intermediate test results often occur with diagnostic tests. When assessing diagnostic accuracy, it is important to properly report and account for these results. In the literature, these results are commonly discarded prior to analysis or treated as either a positive or a negative result. Although such adjustments allow sensitivity and ...
Sampram Ellis S - - 2012
To prospectively evaluate the potential influence of resistance to activated protein C (APC-resistance) on the initial inflammatory response, amputation rate and survival during 10 years of follow-up in patients with critical limb ischemia (CLI). Two hundred and fifty-six consecutive CLI patients were analyzed for APC-ratio, the Factor V Leiden mutation and ...
Stryker Jody J - - 2012
Changes in land use and climate are expected to alter the risk of malaria transmission in areas where rainfall limits vector abundance. We use a coupled hydrology-entomology model to investigate the effects of land use change on hydrological processes impacting mosquito abundance in a highland village of Ethiopia. Land use ...
Ferreira R C - - 2012
PURPOSE: New insights in prognostic predictions are urgently needed for papillary thyroid carcinoma (PTC). The present study aimed to investigate whether computerized analysis of chromatin texture allows the identification of PTC patients with a poor prognosis. METHODS: We randomnly selected paraffin-embedded blocks from surgical specimens of 103 classic cases of ...
Yeates Peter P School of Translational Medicine, Academy at UHSM, [corrected] University of Manchester, Manchester, United Kingdom. - - 2012
Competency-based models of education require assessments to be based on individuals' capacity to perform, yet the nature of human judgment may fundamentally limit the extent to which such assessment is accurately possible. To determine whether recent observations of the Mini Clinical Evaluation Exercise (Mini-CEX) performance of postgraduate year 1 physicians ...
Mantha S - - 2012
Vitamin K antagonists (VKAs) were, until recently, the only option for chronic anticoagulation in patients with atrial fibrillation. Three new oral anticoagulants have been tested for this indication in recent randomized trials: dabigatran, rivaroxaban, and apixaban. They offer the promise of consistent effect without the need for monitoring drug levels. ...
Luo Yu - - 2013
Utilizing a classic stroke model in rodents, middle cerebral artery occlusion (MCAo), we describe a novel neuroregenerative approach using the repeated intranasal administration of cocaine- and amphetamine-regulated transcript (CART) peptide starting from day 3 poststroke for enhancing the functional recovery of injured brain. Adult rats were separated into two groups ...
Birdthistle Isolde - - 2012
Non-consensual sex is associated with HIV infection in Africa, but there is little longitudinal data on this association. We describe reported non-consensual sex among women over two decades in southwest Uganda, including associations with incident HIV infection. Between 1990 and 2008, individuals in a population cohort who recently seroconverted to ...
Kornfeld Ari - - 2012
Laboratory studies indicate that plant respiratory efficiency may decrease in response to low nutrient availability, due to increased partitioning of electrons to the energy-wasteful alternative oxidase (AOX). Field confirmation of this hypothesis is lacking, however. We therefore investigated plant respiratory changes associated with succession and retrogression in soils aged from ...
Mendes Ana Vilela - - 2012
The epidemiological dimension of mental health problems in childhood and its impact warrant new studies. Knowledge about the predictors of mental health in children is scant in developing countries. The present study estimated the prevalence of psychiatric disorders in Brazilian school-age children based on a community sample from primary health ...
Cheng D - - 2012
Mahogunin is an important mediator of chromogenesis and neurodegeneration. Mahoganoid is a mutation of the mahogunin gene, which causes a pleiotropic phenotype that includes suppression of obesity, spongiform neurodegeneration and improvement of insulin sensitivity. Our previous research found that mahoganoid widely expressed in the male rat reproductive system, and mahoganoid-deficient ...
Thapa Raj Kumar - - 2012
Abstract Psoriasis is a chronic relapsing inflammatory skin disorder affecting 2-3 % of world population. In present context, a novel topical formulation that could deliver tacrolimus effectively for psoriasis treatment would be of great interest. Liquid crystalline nanoparticle (LCN) is one of the potential drug delivery systems for topical drug ...
Fiorentino Francesco F GENOMA- Molecular Genetics Laboratory, Rome, Italy. - - 2013
In this study, we aimed to explore the utility of chromosomal microarray analysis (CMA) in groups of pregnancies with a priori low risk for detection of submicroscopic chromosome abnormalities, usually not considered an indication for testing, in order to assess whether CMA improves the detection rate of prenatal chromosomal aberrations. ...
Rusz Orsolya - - 2012
The standard of care in bone metastases is antiresorptive therapy. If present in the bone, tumor cells induce a vicious cycle by stimulating the osteoclasts, which further accelerates tumor progression. The widely-used bisphosphonates or the new therapeutic option, denosumab an inhibitor of the receptor activator of NF-κB ligand (RANKL), interrupt ...
Baiocchi Glauco - - 2012
BACKGROUND: Adenocarcinoma (AC) of the cervix comprises 15-20 % of all cervical carcinomas, and data regarding the prognostic value of histologic type after pelvic exenteration (PE) are lacking. Our aim was to analyze the prognostic value of histologic type in overall survival (OS) and disease-specific survival (DSS) after PE and correlate ...
Verhagen Josine - - 2012
Longitudinal surveys measuring physical or mental health status are a common method to evaluate treatments. Multiple items are administered repeatedly to assess changes in the underlying health status of the patient. Traditional models to analyze the resulting data assume that the characteristics of at least some items are identical over ...
Murata Kazuya - - 2012
Improvement in blood fluidity leads to the prevention of various lifestyle-related diseases. A raw material for improving blood fluidity has been long desired in the research area of functional and supplemental foods. We successfully showed an improvement in blood fluidity by the Zingiberaceae plant, Kaempferia parviflora. The rhizome of the ...
Hatano Ken-Ichi - - 2012
We have previously demonstrated that dark materials (DM) in acidified molasses are effectively adsorbed to Amberlite XAD7HP resin and are eluted from the resin with 0.1 M sodium hydroxide. In this paper, we have characterized the self-assembly behavior of molasses DM by using dynamic and static light scattering in combination with ...
Zinzani Pier Luigi - - 2012
Bronchial-associated lymphoid tissue (BALT) lymphoma is an extranodal primary pulmonary lymphoma. The optimal therapy for this rare disease is still debated, and few heterogeneous data are available in literature. The aim of our study was to critically review data of patients with BALT lymphoma treated in first-line therapy with fludarabine ...
Cobanoglu Aysegul Kudu - - 2012
BACKGROUNDS/AIMS: Atherosclerotic cardiovascular diseases are among the major causes of mortality in renal transplant (RT) patients. Oxidative stress plays an important role in the pathogenesis of atherosclerosis. In this study, we investigated the role of asymmetric dimethylarginine (ADMA) along with oxidized LDL (oxLDL) and antioxidized LDL (anti-oxLDL) on the extent ...
Hahn Bettina - - 2012
ERK is a member of the MAPK pathway with essential functions in cell proliferation, differentiation and survival. Complete ERK activation by the kinase MEK requires dual phosphorylation at T and Y within the activation motif TEY. We show that exposure of primary mouse hepatocytes to hepatocyte growth factor (HGF) results ...
Galli Carlo - - 2012
OBJECTIVES: Phosphoserine-based functionalization has been proposed as a tool to improve integration of endosseous implants by promoting osteoblast adhesion and differentiation in vitro. The present work investigates whether phosphoserine-tethered poly(epsilon-lysine) dendrons, when applied as a film to titanium surfaces, enhance the differentiation of osteoblastic cells and the activation of Wnt/β-catenin ...
Wong Jonathan - - 2012
Smoothly varying muscle fibre orientations in the heart are critical to its electrical and mechanical function. From detailed histological studies and diffusion tensor imaging, we now know that fibre orientations in humans vary gradually from approximately - 70° in the outer wall to +80° in the inner wall. However, the creation ...
Klein B - - 2012
Clinical effects of early childhood chronic stress should be regarded as causing a developmental brain injury. However, current diagnostic constructs fail to capture the associated disabilities in emotional-behavioural regulation of stress and attachment functions adequately. We first focus on neglect as a prototypical early childhood chronic stressor; next we explore ...
Razavi Shahnaz - - 2012
The Schwann cells (SCs) may be obtain from nerve biopsies for autologous transplantation. However, it is difficult to obtain sufficient amount of SCs for clinical applications. Human adipose-derived stem cells (ADSCs) can be induced to differentiate into Schwann-like cells (S-like cells) and used for autologous transplantation. However, effect of leukemia ...
Chu Chi Meng - - 2012
Recent advancements in risk assessment have led to the development of dynamic risk-assessment measures that are predictive of inpatient aggression in the short term. However, there are several areas within this field that warrant further empirical investigation, including whether the average, maximum, or most recent risk state assessment is the ...
Zierkiewicz Wiktor - - 2012
Increase of the atmospheric concentration of halogenated organic compounds is partially responsible for a change of the global climate. In this work we have investigated the interaction between halogenated ether and water, which is one of the most important constituent of the atmosphere. The structures of the complexes formed by ...
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