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Results 351 - 400 of 2633
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Shi Changhua - - 2012
Self-cleaving elastin-like protein (ELP) tags provide a very promising tool for recombinant protein purification. With this method, the target protein is purified by simple ELP-mediated precipitation steps, followed by self-cleavage and removal of the ELP tag. Unfortunately, however, inteins usually experience some level of pre-cleavage during protein expression, which can ...
Guo Wei-Xing - - 2012
BACKGROUND: It is not known whether percutaneous radiofrequency ablation (PRFA) could get the same treatment efficacy and fewer complications as partial hepatectomy (PH) in patients with small centrally located hepatocellular carcinoma (HCC). The present study was designed to evaluate the efficacy of PH and PRFA in the treatment of small ...
Beckerman Stephen - - 2012
There are interesting parallelisms between McCullough et al.'s article and studies of revenge presented by French legal anthropologist Raymond Verdier, particularly as regards the discussion of the increasing likelihood of revenge with increasing social distance. Additionally, the observation that many peoples speak of revenge in the language of debt and ...
Lambrinoudaki Irene - - 2012
Vitamin D receptor's (VDR) genotypes have been associated both with the development of bone disease and the pathogenesis of multiple sclerosis (MS). We aimed to evaluate the association between the presence of Bsm1 restriction fragment length polymorphism of VDR and bone loss in ambulatory patients with MS. This cross-sectional study ...
Sanaeinasab Hormoz - - 2012
To better understand prevalence of physical inactivity among Iranian adolescents, their physical activity behavior across the hypothesized stages of change derived from the transtheoretical model was investigated in this study. This was a cross-sectional study involving 1551 adolescents, 12-14 years of age (941 boys and 610 girls). Participants were selected ...
Noelken Robert - - 2012
AIM: The aim of this study was to evaluate soft and hard tissue alterations around implants placed in healed, sloped ridge sites. MATERIALS AND METHODS: In this prospective multi-center study, 65 patients between 20 and 74 years of age and with a need for a single tooth replacement were included. All ...
Cavalieri Simona - - 2012
Recent development of next-generation DNA sequencing (NGS) techniques is changing the approach to search for mutations in human genetic diseases. We applied NGS to study an A-T patient in which one of the two expected mutations was not found after DHPLC, cDNA sequencing and MLPA screening. The 160-kb ATM genomic ...
Fischer-Stabauer Mattias - - 2012
Interleukin (IL)-17 is a key molecule for epithelial immunity and inflammation. Objectives: To quantify IL-17 expression in situ in a large panel of cutaneous diseases. 289 samples of the 30 most common cutaneous infectious, autoimmune, inflammatory and tumor diseases were stained for IL-17 immunohistochemically. IL-17 expression strongly varied between the ...
Brooks-Russell Ashley - - 2012
This study identified classes of developmental trajectories of physical dating violence victimization from grades 8 to 12 and examined theoretically-based risk factors that distinguished among trajectory classes. Data were from a multi-wave longitudinal study spanning 8th through 12th grade (n = 2,566; 51.9 % female). Growth mixture models were used to identify trajectory ...
Stan Claudiu A - - 2012
Hydrodynamic lift forces offer a convenient way to manipulate particles in microfluidic applications, but there is little quantitative information on how non-inertial lift mechanisms act and compete with each other in the confined space of microfluidic channels. This paper reports measurements of lift forces on nearly spherical drops and bubbles, ...
Huang Kai - - 2012
A cost-effective biosorbent was prepared by a green chemical modification process from muskmelon peel by saponification with alkaline solution of Ca(OH)(2). Its adsorption behavior for lead ions was investigated and found to exhibit excellent adsorption properties. Results showed that the optimal equilibrium pH range for 100 % adsorption is from 4 ...
Fujisawa Yasuhiro - - 2012
Abstract Objective To show the efficacy of taxane-based chemotherapy for the treatment of cutaneous angiosarcoma. Methods A case-control study comparing patients who received taxanes without wide local excision (group A, n=5) and patients who received conventional surgery-based therapy (group B, n=8) in one university hospital in eastern Japan. Data were ...
Paulik Georgie - - 2012
Background: There has been a recent focus on the interpersonal nature of the voice hearing experience, with studies showing that similar patterns of relating exist between voice hearer and voice as between voice hearer and social others. Two recent therapeutic approaches to voices, Cognitive Therapy for Command Hallucinations and Relating ...
Jolivet C - - 2012
Genetic diversity strongly influences populations' adaptability to changing environments and therefore survival. Sustainable forest management practices have multiple roles including conservation of genetic resources and timber production. In this study, we aimed at better understanding the variation in genetic diversity among adult and offspring individuals, and the effects of mating ...
Parejiya Punit B - - 2012
The study was aimed toward development of modified release oral drug delivery system for highly water soluble drug, Milnacipran HCl (MH). Novel Tablet in Tablet system (TITs) comprising immediate and extended release dose of MH in different parts was fabricated. The outer shell was composed of admixture of MH, lactose ...
Szymańska Ewelina - - 2012
A detailed experimental investigation of the dissociative electron attachment (DEA) process to acetaldehyde, CH(3)CHO is presented. To investigate this process we use a time of flight spectrometer coupled with the velocity slice imaging technique. DEA in CH(3)CHO is found to lead to the formation of CH(3)(-), O(-), OH(-), C(2)H(-), C(2)HO(-) ...
Sun Hokeun - - 2012
The matched case-control designs are commonly used to control for potential confounding factors in genetic epidemiology studies especially epigenetic studies with DNA methylation. Compared with unmatched case-control studies with high-dimensional genomic or epigenetic data, there have been few variable selection methods for matched sets. In an earlier paper, we proposed ...
Wang Shin-Yi - - 2012
This meta-analysis used hierarchical linear modeling to examine 115 single-case studies with 343 participants that examined the effectiveness of social skills interventions for individuals with autism spectrum disorder (ASD). The average effect size of the included studies was 1.40 (SD = 0.43, 95 % CL = 1.32-1.48, N = 115). In the further, several common predictors including ...
Shin Sung - - 2012
BACKGROUND: To evaluate whether the preoperative magnetic resonance angiography (MRA) can predict the risk of cerebral ischemia associated with the carotid endarterectomy (CEA). METHODS: Between January 2004 and December 2010, 382 consecutive patients (mean age: 56.6 years; range: 45-78 years) were identified to have undergone preoperative MRA and the CEA under regional ...
Konečni Vladimir J - - 2012
This commentary discusses dozens of ecologically powerful social-psychological experiments from the1960s and 1970s, which are highly relevant especially for predicting the consequences of revenge. McCullough et al. omitted this work - perhaps because of its misclassification as "catharsis" research. The findings are readily accommodated by Konečni's anger-aggression bidirectional-causation (AABC) model ...
van der Meide Hanneke - - 2012
Phenomenological healthcare research should include the lived experiences of a broad group of healthcare users. In this paper it is shown how shadowing can give a voice to people in vulnerable situations who are often excluded from interview studies. Shadowing is an observational method in which the researcher observes an ...
Yamashita Suguru - - 2012
BACKGROUND: Although portal vein embolization (PVE) has been applied for surgical resection of colorectal liver metastases (CLM), the clinical usefulness of liver surgery following PVE for CLM remains unknown. METHODS: A total of 115 patients were evaluated retrospectively. Among them, 49 underwent one-stage hepatectomy following PVE (PVE group). The remaining ...
Eva Kevin W - - 2012
There has been difficulty designing medical school admissions processes that provide valid measurement of candidates' nonacademic qualities. To determine whether students deemed acceptable through a revised admissions protocol using a 12-station multiple mini-interview (MMI) outperform others on the 2 parts of the Canadian national licensing examinations (Medical Council of Canada ...
Mojid Mondol Mohamad Abdul - - 2012
In the course of our ongoing research for antimicrobial agents, we isolated five new compounds, three 24-membered macrolactones, macrolactins X-Z (1-3) and two hydroxy unsaturated fatty acids, linieodolides A (5) and B (6), together with a known metabolite, macrolactinic acid (4), from the culture broth of a marine Bacillus sp. ...
Nagy K - - 2012
Background/Objectives:The vitamin E derivative, α-tocopheryl acetate, is often included in formulations used in enteral nutrition. In this respect, we compared α-tocopherol and α-tocopheryl acetate absorption under 'maldigestion' conditions, such as occurring during enteral tube feeding, using differentially labeled RRR-[5,7-methyl-((2)H(6))]-α-tocopherol and RRR-[5-methyl-(2)H(3)]-α-tocopheryl acetate allowing direct comparison between free and esterified forms.Subjects/Methods:The ...
Han Yi - - 2012
Glutathione is a determinant of cellular redox state with roles in defence and detoxification. Emerging concepts suggest that this compound also has functions in cellular signalling. Here, we report evidence that glutathione plays potentially important roles in setting signalling strength through the jasmonic acid (JA) pathway. First, we show that ...
Saavedra-Montañez Manuel - - 2012
BACKGROUND: In the present study, we analyzed the presence of antibodies to four different influenza viruses (pH1N1, hH1N1, swH1N1, and swH3N2) in the sera of 2094 backyard pigs from Mexico City. The sera were obtained between 2000 and 2009. OBJECTIVES: The aim of this study was to perform a retrospective ...
Howard David L - - 2012
To determine what factors are predictive of post-Essure hysterosalpingogram (HSG) compliance. We conducted a retrospective chart review of all patients who underwent the Essure procedure at the two campuses of the Truman Medical Center, Kansas City, Missouri, from January 1, 2005 through December 31, 2010. Our study population consisted primarily ...
Mijnendonckx K - - 2012
Four Cupriavidus metallidurans and eight Ralstonia pickettii isolates from the space industry and the International Space Station (ISS) were characterized in detail. Nine of the 12 isolates were able to form a biofilm on plastics and all were resistant to several antibiotics. R. pickettii isolates from the surface of the ...
Yaseen Mehwish - - 2012
In vitro plant cells, tissues and organ cultures are not fully autotrophic establishing a need for carbohydrates in culture media to maintain the osmotic potential, as well as to serve as energy and carbon sources for developmental processes including shoot proliferation, root induction as well as emission, embryogenesis and organogenesis, ...
Gutleben Klaus-Jürgen - - 2012
During recent years the need for intraprocedural imaging has increased. Fluoroscopy and angiography are frequently supplemented by pre-procedural magnetic resonance or computed tomography imaging as well as electroanatomic mapping techniques. However, poor real-time imaging quality of soft tissue, radiation exposure, and contrast media consumption are disadvantageous. Ultrasound techniques are characterized ...
Savy Vilma - - 2012
Please cite this paper as: Savy et al. (2012) Burden of influenza in Latin America and the Caribbean: a systematic review and meta-analysis. Influenza and Other Respiratory Viruses DOI: 10.1111/irv.12036. Objective  Influenza causes severe morbidity and mortality. This systematic review aimed to assess the incidence, etiology, and resource usage for influenza ...
Sayre Casey L - - 2012
An analytical method enabling the detection and quantification of the individual enantiomers of racemic (±) pinocembrin is required to fully characterize its pharmacokinetic disposition. Direct resolution of the enantiomers of pinocembrin was achieved using a novel and simple reversed-phase high-performance liquid chromatography method with electrospray ionization and detection by mass ...
Karremans Johan C - - 2012
The target article's evolutionary approach provides an excellent framework for understanding when and why people retaliate or forgive. We argue that recent findings on the basic processes in forgiveness - particularly, the role of executive control - can further refine the authors' proposed model. Specifically, the lack of executive control may restrict the explanatory ...
Zhao Xin - - 2012
Danshen (DS) is a widely used traditional Chinese medicine for treating cardiovascular and cerebrovascular diseases. A simple, rapid and sensitive method was developed for identification of the in vivo metabolites in urine of WZS-miniature pigs after oral administration of DS decoction by HPLC coupled with diode array detection with electrospray ...
Locatelli Isabella - - 2012
We consider the problem of estimating the mean hospital cost of stays of a class of patients (e.g., a diagnosis-related group) as a function of patient characteristics. The statistical analysis is complicated by the asymmetry of the cost distribution, the possibility of censoring on the cost variable, and the occurrence ...
Tran Bach X - - 2012
OBJECTIVE: To assess the out-of-pocket (OOP) payments for health-care services of HIV/AIDS patients, and identify associated factors in Vietnam. METHODS: Cross-sectional multisite survey of 1016 HIV/AIDS patients attending 7 hospitals and health centres in Ha Noi, Hai Phong and Ho Chi Minh City in 2012. RESULTS: HIV/AIDS patients used inpatient ...
van der Lem R - - 2012
PURPOSE: Sociodemographic and socioeconomic characteristics of participants in antidepressant and psychotherapy efficacy trials (AETs and PETs) for major depressive disorder (MDD) may limit the generalizability of the results. We compared trial participants with daily practice patients. We subsequently assessed the influence of socio-demographic and socioeconomic status on treatment outcome in ...
Sajovic Matjaz - - 2012
PURPOSE: The ideal treatment for patients presenting with bilateral anterior cruciate ligament (ACL) deficiency remains controversial. The purpose was to evaluate cost and functional results after one-stage bilateral ACL reconstruction using either hamstring or patella tendon autograft. METHODS: This prospective comparative study was compared the mid-term outcome of 7 patients ...
Tabatabaei-Panah Akram-Sadat - - 2012
Here we introduce novel optical properties and accurate sensitivity of Quantum dot (QD)-based detection system for tracking the breast cancer marker, HER2. QD525 was used to detect HER2 using home-made HER2-specific monoclonal antibodies in fixed and living HER2(+) SKBR-3 cell line and breast cancer tissues. Additionally, we compared fluorescence intensity ...
Rosa Fernández-Torres - - 2012
Abstract Introduction: Efficacy and safety of etanercept have been proved in numerous clinical trials; however efficacy is determined by means of PASI 75 and few studies consider the maintenance of long-term response. The aim of this study is to provide data on long-term response to etanercept monotherapy in daily practice ...
Nana-Sinkam S P - - 2013
The discovery that noncoding components of the genome, including microRNA (miRNA or miR), can contribute to the pathogenesis of cancer has led investigators to contemplate using these molecules to guide clinical decision making. Currently, miRNA signatures are being applied in human clinical trials and miRNA-directed therapy is under way, with ...
Maserati Marc - - 2012
Summary RNA transcription, processing and translation are fundamental molecular processes required for development, growth and cell viability. Towards the functional annotation of the genome, we are engaged in a reverse genetic screen using mammalian preimplantation embryos as a model system. Here we report the essential function of four RNA processing/splicing ...
Aureli Filippo - - 2012
Humans have the cognitive abilities to implement the revenge and forgiveness systems hypothesized by McCullough et al., but the evidence suggests that simpler processes may underlie most revenge cases in humans and other animals. The mediating role of emotions can be at the basis of the flexibility needed in the ...
Gertnere Jana - - 2012
AIM: To compare 1-year results of the refractive lenticule extraction (ReLEx) flex technique performed as a commercial bilateral simultaneous procedure to a matched group of wavefront-optimized Femto-Lasik for correction of myopia and astigmatism with emphasis on contrast sensitivity and high-order aberrations (HOA). METHODS: In this retrospective study 44 eyes of ...
Melton L J LJ - - 2012
Adjusting for age, sex, and precipitating cause, the relative risk of death was increased following fractures at most skeletal sites. INTRODUCTION: This study aims to determine long-term survival following fractures due to any cause at each skeletal site. METHODS: In a historical cohort study, 2,901 Olmsted County, MN, USA, residents ...
Fraga-Silva Rodrigo Araujo - - 2012
It is well known that the renin-angiotensin system (RAS) plays a pivotal role in the pathophysiology of cardiovascular diseases. This is well illustrated by the great success of ACE inhibitors and angiotensin (Ang) II AT(1) blockers in the treatment of hypertension and its complications. In the past decade, the classical ...
Ruan Liang-Liang - - 2012
Aminoacyl-tRNA synthetases (aaRSs) are responsible for ensuring the fidelity of the genetic code translation by accurately linking a particular amino acid to its cognate tRNA isoacceptor. To ensure accuracy of protein biosynthesis, some aaRSs have evolved an editing process to remove mischarged tRNA. The hydrolysis of the mischarged tRNA usually ...
Edwards Paul R - - 2012
Hyperspectral cathodoluminescence imaging provides spectrally and spatially resolved information on luminescent materials within a single dataset. Pushing the technique toward its ultimate nanoscale spatial limit, while at the same time spectrally dispersing the collected light before detection, increases the challenge of generating low-noise images. This article describes aspects of the ...
Pahlavan Farzaneh - - 2012
This commentary focuses on how third parties impact the course of acts of revenge based on their world views, such as belief in a just world. Assuming this belief to be true, the following questions could be asked: (a) What are the consequences of a third party's worldview in terms ...
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