Search Results
Results 201 - 250 of 2633
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Farjami Elahe - - 2012
The inherent redox activity of dopamine enables its direct electrochemical in vivo analysis (Venton and Wightman, Anal. Chem. (2003) 414A). However, dopamine analysis is complicated by the interference from other electrochemically active endogenous compounds present in the brain, including dopamine precursors and metabolites and other neurotransmitters (NT). Here we report ...
Alvarez Celedonio M - - 2012
The use of Schiff condensation followed by CuAAC affords complexes containing iminopyridine ligands functionalized either with a triazole ring or with a sulfonyl amido group via ring opening of the unstable sulfonyl triazole.
Hines John - - 2012
The purpose of this article is to illustrate and discuss the various etiologies of perforation of the mesenteric small bowel and associated findings on abdominal CT. Perforation of the mesenteric small bowel is an uncommon cause of an acute abdomen and can be due to various etiologies. In underdeveloped countries, ...
Park Sung Keun - - 2012
There have been several reports about clinical association between type 2 diabetes mellitus (DM) and non-alcoholic fatty liver disease (NAFLD). However, most of studies were about the unilateral effects of type 2 DM on NAFLD, and studies for the reverse relation were rare. Thus, this study was designed to investigate ...
Simmons L W - - 2012
Reproductive proteins are amongst the most evolutionarily divergent proteins known, and research on genetically well-characterized species suggests that postcopulatory sexual selection might be important in their evolution; however, we lack the taxonomic breadth of information on reproductive proteins that is required to determine the general importance of sexual selection for ...
Westhaus Sandra - - 2012
Oxidized low density lipoprotein (oxLDL) has been reported as an inhibitor of hepatitis C virus (HCV) cell entry making it the only known component of human lipid metabolism with an anti-viral effect on HCV. However, several questions remain open including its effect on full length cell culture grown HCV (HCVcc) ...
Norby Kiersten E - - 2012
BACKGROUND: Intracerebral hemorrhage (ICH) is an infrequent complication of intravenous recombinant tissue plasminogen activator (rt-PA) for the treatment of acute stroke. However, such ICH is an important reason for withdrawal of care because of lack of adequate data regarding long-term patient outcomes. OBJECTIVE: To report the long-term outcomes in patients ...
Alharbi R A - - 2012
The HOX genes are a highly conserved family of homeodomain-containing transcription factors that specify cell identity in early development and, subsequently, in a number of adult processes including hematopoiesis. The dysregulation of HOX genes is associated with a number of malignancies including acute myeloid leukemia (AML) and acute lymphoid leukemia ...
Kountouri Aggeliki M - - 2012
Colorectal cancer is one of the major causes of cancer-related mortality in humans in both developed and developing countries. Dietary patterns influence the risk of colon cancer development, while plant-derived foods have gained great interest, due to the high content of antioxidants. Corinthian raisins (Currants, CR) and Sultanas (S) (Vitis ...
Oksaharju Anna - - 2012
A high-fat diet disturbs the composition and function of the gut microbiota and generates local gut-associated and also systemic responses. Intestinal mast cells, for their part, secrete mediators which play a role in the orchestration of physiological and immunological functions of the intestine. Probiotic bacteria, again, help to maintain the ...
Kimori Yoshitaka - - 2012
In this paper, we described our attempt to characterize rough 3-D feature of the structural analogue of the key-intermediate of myosin's crossbridge cycle. Utilizing quick-freeze deep-etch replica electron microscopy, we observed that actin-attached myosin during in vitro sliding was bent superficially as postulated in the conventional hypothesis, but toward the ...
Sun B F - - 2012
Eukaryotic horizontal gene transfer (HGT) events are increasingly being discovered yet few reports have summarized multiple occurrences in a wide range of species. We systematically investigated HGT events in the order Lepidoptera by employing a series of filters. Bombyx mori, Danaus plexippus and Heliconius melpomene had 13, 12 and 12 ...
Rienks J - - 2012
BACKGROUND/OBJECTIVES:To investigate the association between dietary patterns and prevalence and incidence 3 years later of depressive symptoms using data from the mid-aged cohort in the Australian Longitudinal Study on Women's Health.SUBJECTS/METHODS:Participants (aged 50-55 years) completed a food frequency questionnaire in 2001. Depressive symptoms were measured in 2001 and 2004 using ...
Liu Fang - - 2012
ABSTRACT This study aimed to develop a novel multiplex reverse transcription-nested polymerase chain reaction (RT-nPCR) assay to accurately and effectively detect 10 common gene rearrangements in adult acute lymphoblastic leukemia (ALL) and to examine the clinicopathologic characteristics and other genetic aberrations of ALL patients expressing different fusion genes. Our RT-nPCR ...
Delbe-Bertin Laëtitia - - 2012
BACKGROUND: Rituximab (RTX) is a promising strategy for treating steroid-dependent idiopathic nephrotic syndrome (SDNS). RTX induces profound B-cell depletion, suggesting hypogammaglobulinemia as a potential side effect after long-term treatment. PATIENTS AND METHODS: We analyzed immunoglobulin G (IgG) levels in 12 pediatric patients on RTX with a B-cell depletion of a ...
Balliet Daniel - - 2012
We address how trait self-control and trait concern for others relate to the concepts of monitored and intrinsic Welfare Tradeoff Ratios (WTRs), respectively, and how recent work on personality, revenge, and forgiveness are informed by the adaptationist perspective proposed in the target article. We also discuss how the proposed adaptationist ...
Shin Jonghyun - - 2012
Syndecan-4 (S4) is a cell membrane-associated heparan sulfate proteoglycan that forms oligomers in muscle satellite cells. The S4 oligomers activate protein kinase Cα (PKCα) through the S4 cytoplasmic domain and may regulate the activation of ras homolog gene family member A (RhoA), a signal transduction molecule down-stream of PKCα which ...
Leiser David - - 2012
McCullough et al. suggest that revenge and forgiveness rest upon risk computation. Risk computation is implemented by emotions that evolved for additional functions, giving rise to phenomena such as betrayal aversion and taboo-tradeoffs, and specific patterns of forgiveness we have documented. A complete account of revenge and reconciliation should incorporate ...
You Xiangwei - - 2012
Field trials were carried out to investigate the dissipation and residue levels of bifenthrin in wheat. After extraction with acetonitrile, the samples were cleaned up by dispersive solid-phase extraction and detected by gas chromatography-mass spectrometry. The half-lives of bifenthrin in wheat seedlings ranged from 2.4 to 10.5 days. At harvest time, ...
Guidotti Rebecca - - 2012
Cleaning and disinfection of the root canal system are some of the most important goals in endodontic therapy. The aim of this preliminary study is to assess the effectiveness of Er:YAG laser fiber in removing the smear layer produced during root canal walls instrumentation. Forty-eight single-rooted teeth were prepared with ...
Mao Xiangbing - - 2012
Leucine and leptin play important roles in regulating protein synthesis and degradation in skeletal muscles in vitro and in vivo. However, the objective of the present study was to determine whether leptin and leucine function synergistically in regulating protein metabolism of skeletal muscles. In the in vitro experiment, C2C12 myotubes ...
Wereha Tyler J - - 2012
Applying a non-developmental evolutionary metatheory to understanding the evolution of psychological capacities leads to the creation of models that mischaracterize developmental processes, misattribute genes as the source of developmental information, and ignore the myriad developmental and contextual factors involved in human decision-making. Using an evolutionary systems perspective, we argue that ...
Nath Kaushik - - 2012
Utilization of agrowaste materials for the production of activated carbon, as an excellent adsorbent with large surface area, is well established industrially, for dephenolation of wastewater. In the present work, dried pods of Prosopis cineraria-a novel and low-cost agrowaste material-were used to prepare activated carbons by zinc chloride activation. Batch ...
Kulier Regina - - 2012
For evidence-based practice to embed culturally in the workplace, teaching of evidence-based medicine (EBM) should be clinically integrated. In low-middle-income countries (LMICs) there is a scarcity of EBM-trained clinical tutors, lack of protected time for teaching EBM, and poor access to relevant databases in languages other than English. To evaluate ...
Silberstein S D - - 2012
Migraine is a primary brain disorder resulting from altered modulation of normal sensory stimuli and trigeminal nerve dysfunction. The second edition of the International Classification of Headache Disorders (ICHD-2) defines seven subtypes of migraine. Migraine treatment can be acute or preventive. New targeted therapies include 5-HT(1F) receptor agonists, calcitonin gene-related ...
Castranova Vincent - - 2012
Carbon nanotubes (CNTs) are carbon atoms arranged in a crystalline graphene lattice with a tubular morphology. CNTs exhibit high tensile strength, possess unique electrical properties, are durable, and can be functionalized. These properties allow applications as structural materials, in electronics, as heating elements, in batteries, in the production of stain-resistant ...
Unterbrink Thomas - - 2012
PURPOSE: In order to evaluate a manual-based group program for teachers aiming at strengthening mental health, we examined (1) whether the teachers interested in participating differ from their colleagues without interest and (2) whether there is evidence of subgroups benefiting more than others among those who participated. METHODS: Out of ...
Leite Hianna Almeida Câmara - - 2012
Clonal genotypes resistant to fungal diseases are an important component of the cocoa production system in southeastern Bahia state (Brazil), so that technologies for faster production of stronger and healthier plantlets are highly desirable. In this study, the effects of inoculated bacterial endophytes isolated from healthy adult cacao plants on ...
Lao T T - - 2012
SUMMARY We examined the impact of the neonatal hepatitis B immunization programme, first provided to all neonates born to mothers screened positive for hepatitis B surface antigen (HBsAg) in late 1983, on the age-specific prevalence of HBsAg carriage in teenage mothers managed in 1998-2008. HBsAg carriage was found in 2·5%, ...
Tanaka Yoshiya - - 2012
Rheumatoid arthritis (RA) is a representative autoimmune disease characterized by chronic and destructive inflammatory synovitis. The multiple cytokines play pivotal roles in RA pathogenesis by inducing intracellular signaling, and members of the Janus kinase (JAK) family are essential for such signal transduction. An orally available JAK3 inhibitor, tofacitinib, has been ...
Fischer Steven L - - 2012
Accurate estimation of occupational performance capability facilitates better job (re-) design by informing workplace parties about the potential mismatches between job demands and the capability of their labour force. However, estimating occupational performance requires consideration of multiple factors that may govern capacity. In this paper, a novel model is described ...
Potegal Michael - - 2012
Revenge appears among a "suite" of social interactions that includes competition, alliance building (a prerequisite for tribal revenge raids), and so forth. Rather than a modular "system" directly reflecting evolutionary fitness constraints, revenge may be (another) social cost-benefit calculation involving potential or actual aggression and proximately controlled by individual personality ...
El Bestawy Ebtesam - - 2012
The present study aimed to overcome the toxicity of the heavy metals load, discharged with the industrial effluents into Alexandria sewerage network, on the activated sludge treatment system through effective acclimation for organic matter and heavy metals removal. Optimization and/or acclimatization of the activated sludge process in the presence of ...
Johnson-Freyd Sasha - - 2012
McCullough et al. hypothesize that evolution has selected mechanisms for revenge to deter harms and for forgiveness to preserve valuable relationships. However, in highly dependent relationships, the more adaptive course of action may be to remain unaware of the initial harm rather than risk alienating a needed other. We present ...
Liu Gui-Lei - - 2012
Two MOF-74 analogs with OH groups on 1D channel surfaces have been synthesized through multi-component self-assembly at room temperature. Their guest-free forms demonstrate a potential luminescent probe or sensor for small molecules, and OH-MOF-74 () also showed exceptional fluorescence quenching and enhancement behavior for different types of aromatic molecules.
McCullough Michael E - - 2012
Minimizing the costs that others impose upon oneself and upon those in whom one has a fitness stake, such as kin and allies, is a key adaptive problem for many organisms. Our ancestors regularly faced such adaptive problems (including homicide, bodily harm, theft, mate poaching, cuckoldry, reputational damage, sexual aggression, ...
Yu Junchi - - 2012
Transcription factor (TF) and microRNA (miRNA) are two best characterized gene regulators that have been found to play an important role in gene regulation. However, high throughput screening the interaction relationships between transcription factors, microRNAs, and target genes in gliomas remains rare. Using GSE16666 and GSE13091 datasets downloaded from Gene ...
Manz Thomas A - - 2012
In recent years, several methods have been developed that partition the electron density among atoms using spherically symmetric atomic weights. D. E. P. Vanpoucke, P. Bultinck, and I. Van Driessche (J. Comput. Chem. 2012, doi: 10.1002/jcc.23088) recently reported a periodic implementation of the Hirshfeld-I method that uses a combination of ...
Orasan Remus Aurel - - 2012
PURPOSE: The study of online hemodiafiltration (HDF) benefits over high-flux hemodialysis (HD) raises great interest. The purpose was to compare clinical and laboratory parameters in patients treated with HD who were switched to HDF. METHODS: Forty-eight HD patients (study group) were switched to HDF, while other 521 patients remained on ...
Koehler Fabian M - - 2012
Graphene is a two-dimensional crystalline carbon allotrope that has fascinated researchers worldwide and has extended the interest in carbon structures such as fullerenes and nanotubes. In this Account, we use electrical characterization tools to study chemistry on supported graphene. These experiments elucidate the way covalently bound phenyl units can change ...
Bräuner Elvira V - - 2012
Radon-222 gas arises from the radioactive decay of radium-226 and has a 3.8 day half-life. This gas percolates up through soil into buildings, and if it is not evacuated there can be much higher exposure levels indoors than outdoors, which is where human exposure occurs. Radon exposure is classified as ...
Eroldo─čan Tufan O - - 2012
Monounsaturated fatty acids (MUFA)-rich and n-6 polyunsaturated fatty acid (n-6 PUFA)-rich vegetable oils are increasingly used as fish oil replacers for aquafeed formulation. The present study investigated the fatty acid metabolism in juvenile European sea bass (Dicentrarchus labrax, 38.4 g) fed diets containing fish oil (FO, as the control treatment) or ...
Schmudde I - - 2012
The pathways underlying dendritic cell (DC) activation in allergic asthma are incompletely understood. Here we demonstrate that adoptive transfer of ovalbumin-pulsed wild-type (wt) but not of C5a receptor-deficient (C5aR(-/-)) bone marrow (BM)-derived DCs (BMDCs) induced mixed T helper type 2 (Th2)/Th17 maladaptive immunity, associated with severe airway hyperresponsiveness, mucus production, ...
Xu Huiping - - 2012
Intermediate test results often occur with diagnostic tests. When assessing diagnostic accuracy, it is important to properly report and account for these results. In the literature, these results are commonly discarded prior to analysis or treated as either a positive or a negative result. Although such adjustments allow sensitivity and ...
Sampram Ellis S - - 2012
To prospectively evaluate the potential influence of resistance to activated protein C (APC-resistance) on the initial inflammatory response, amputation rate and survival during 10 years of follow-up in patients with critical limb ischemia (CLI). Two hundred and fifty-six consecutive CLI patients were analyzed for APC-ratio, the Factor V Leiden mutation and ...
Stryker Jody J - - 2012
Changes in land use and climate are expected to alter the risk of malaria transmission in areas where rainfall limits vector abundance. We use a coupled hydrology-entomology model to investigate the effects of land use change on hydrological processes impacting mosquito abundance in a highland village of Ethiopia. Land use ...
Ferreira R C - - 2012
PURPOSE: New insights in prognostic predictions are urgently needed for papillary thyroid carcinoma (PTC). The present study aimed to investigate whether computerized analysis of chromatin texture allows the identification of PTC patients with a poor prognosis. METHODS: We randomnly selected paraffin-embedded blocks from surgical specimens of 103 classic cases of ...
West Colin P - - 2012
Current medical training models in the United States are unlikely to produce sufficient numbers of general internists and primary care physicians. Differences in general internal medicine (GIM) career plans between internal medicine residency program types and across resident demographics are not well understood. To evaluate the general medicine career plans ...
Wang Xin - - 2012
Marine macroalgae are known to harbor large populations of microbial symbionts, and yet, microbe symbiosis in invasive macroalgae remains largely unknown. In this study, we applied molecular methods to study microbial communities associated with two invasive algae Acanthophora spicifera and Gracilaria salicornia and the two native algae Gracilaria coronopifolia and ...
Nazer Babak - - 2012
Albuminuria has been shown to be associated with mortality and cardiovascular events, independent of traditional cardiovascular risk factors. This suggests that albuminuria may not just represent glomerular damage, but may be a marker of more diffuse endothelial dysfunction. We investigated the relationship between urinary albumin levels after an acute coronary ...
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