Search Results
Results 651 - 700 of 2635
< 9 10 11 12 13 14 15 16 17 18 19 >
Baig R B Nasir - - 2012
The use of magnetic nanoparticles (MNPs) as a catalyst support in organic synthesis is summarized. The recovery of expensive catalysts after catalytic reaction and reusing them without losing their activity is an essential feature in the sustainable process development. The aim of this article is to highlight the progress in ...
Gürbüz Elif I - - 2012
Hold the water: The hemicellulose fraction of lignocellulose can be converted into furfural in high yields (80 %) using solid acid catalysts (H-mordenite) in a monophasic system with γ-valerolactone (GVL) as the solvent. Furfural degradation reactions are decreased significantly when the water concentration in GVL is minimized, thus resulting in high ...
Larsson Christel - - 2012
Abstract Objective. The purpose of this pilot study was to evaluate the long-term clinical performance of implant-supported full-arch zirconia-based fixed dental prostheses (FDPs). Materials and methods. Ten patients received full-arch zirconia-based (Cercon) mandibular FDPs supported by four implants (Astra Tech). Nine patients received 10-unit FDPs and one patient received a ...
Desai Shyamal D SD Department of Biochemistry and Molecular Biology, Louisiana State University Health Sciences Center School of Medicine, New Orleans, Louisiana 70112, - - 2013
Ataxia-telangiectasia (A-T) is a cerebellar neurodegenerative disorder; however, the basis for the neurodegeneration in A-T is not well established. Lesions in the ubiquitin and autophagy pathways are speculated to contribute to the neurodegeneration in other neurological diseases and may have a role in A-T neurodegeneration. Our recent studies revealed that ...
Gupta Aditi A Division of Pulmonary and Critical Care, Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland 21201, - - 2013
Heat shock protein (Hsp) 70 expression can be stimulated by febrile range temperature (FRT). Hsp70 has been shown to be elevated in serum of patients with sepsis, and when released from cells, extracellular Hsp70 exerts endotoxin-like effects through Toll-like receptor 4 (TLR4) receptors. Circulating TLR agonists and fever both persist ...
Grabauskas Gintautas G Division of Gastroenterology, Department of Internal Medicine, University of Michigan, 3912 Taubman Center, SPC 5362, 1500 East Medical Center Drive, Ann Arbor, MI 48109, - - 2013
Glucosensing nodose ganglia neurons mediate the effects of hyperglycemia on gastrointestinal motility. We hypothesized that the glucose-sensing mechanisms in the nodose ganglia are similar to those of hypothalamic glucose excited neurons, which sense glucose through glycolysis. Glucose metabolism leads to ATP-sensitive potassium channel (K(ATP)) channel closure and membrane depolarization. We ...
Díez Isabel - - 2012
Fluorescent clusters of several Ag atoms are fluorophores with a large set of attractive properties including sub-nanometer size, high fluorescence quantum yield and large Stokes shift. When formed on polymeric scaffolds they exhibit a broad range of heterogeneities in excitation and emission spectra. Addressing this issue we provide detailed spectroscopic ...
Soares Fraser - - 2012
NLRX1 is a member of the Nod-like receptor family of intracellular sensors of microbial- and danger-associated molecular patterns. NLRX1 has a N-terminal mitochondrial addressing sequence that localizes the protein to the mitochondrial matrix. Recently, conflicting reports have been presented with regard to the putative implication of NLRX1 as a negative ...
El-Mounayri Omar - - 2012
AIMS: Despite the diverse developmental origins of vascular smooth muscle cells (VSMCs), recent attempts to generate VSMCs from human embryonic stem cells (hESCs) differentiated along various lineages did not yield distinct cell phenotypes. The aim of this study was to derive and characterize functional coronary-like VSMCs from hESCs using serum-free ...
Grossman Rachel - - 2012
BACKGROUND: Awake-craniotomy allows maximal tumor resection, which has been associated with extended survival. The feasibility and safety of awake-craniotomy and the effect of extent of resection on survival in the elderly population has not been established. The aim of this study was to compare surgical outcome of elderly patients undergoing ...
Troiani Vanessa - - 2012
Neuroimaging studies have identified brain regions that respond preferentially to specific stimulus categories, including 3 areas that activate maximally during viewing of real-world scenes: The parahippocampal place area (PPA), retrosplenial complex (RSC), and transverse occipital sulcus (TOS). Although these findings suggest the existence of regions specialized for scene processing, this ...
Su Jie - - 2012
A silicogermanate, PKU-12, with the - type of zeolite framework was hydrothermally synthesized under fluoride media using diisopropylethylmethylammonium as a structure directing agent. The formation of the silicogermanate zeolite with 20-ring channels has not only extended the - family from phosphates into silicogermanates, but also demonstrated its structural diversity.
Al-Wadei Mohammed H MH Experimental Oncology Laboratory, Department of Biomedical and Diagnostic Sciences, College of Veterinary Medicine, University of Tennessee, Knoxville, 37996, - - 2013
Pancreatic cancer has a high mortality rate and alcoholism is a risk factor independent of smoking. We have shown that nicotinic acetylcholine receptors (nAChR) regulate pancreatic ductal epithelia and pancreatic ductal adenocarcinoma (PDAC) cells in an autocrine fashion by stimulating their production of the stress neurotransmitters noradrenaline and adrenaline that ...
Puntoni Matteo - - 2012
Background: Inflammation and oxidative stress play a crucial role in the development of colorectal cancer (CRC) and interference with these mechanisms represents a strategy in CRC chemoprevention. Allopurinol, a safe molecular scavenger largely employed as anti-gout agent, has been shown to increase survival of patients with advanced CRC and to ...
Cho Eunsoo - - 2012
The purpose of this study was to examine the role of a dynamic assessment (DA) of decoding in predicting responsiveness to Tier 2 small-group tutoring in a response-to-intervention model. First grade students (n = 134) who did not show adequate progress in Tier 1 based on 6 weeks of progress ...
Koutentis Panayiotis A - - 2012
The thermolysis of several N-(4-chloro-5H-1,2,3-dithiazol-5-ylidene)pyridin-n-amines (where n = 2, 3 and 4) gives a mixture of thiazolopyridine-2-carbonitriles in low to moderate yields. Introduction, by design, of a chlorine substituent at the C2 or C4 position of N-(4-chloro-5H-1,2,3-dithiazol-5-ylidene)pyridin-3-amine and other selected azines enables a BnEt(3)NI mediated ANRORC style ring transformation that ...
Dehghan Mahshid M Population Health Research Institute, DBCVSRI, Hamilton General Hospital, 237 Barton St E, Hamilton, ON, Canada L8L 2X2. - - 2012
Diet quality is strongly related to cardiovascular disease (CVD) incidence, but little is known about its impact on CVD events in older people at high risk of CVD and receiving effective drugs for secondary prevention. This study assessed the association between diet quality and CVD events in a large population ...
Czoty Paul W PW Department of Physiology and Pharmacology, Wake Forest University School of Medicine, Medical Center Boulevard, Winston-Salem, NC 27157-1083, - - 2013
Dopamine D2/D3 receptor partial agonists have been suggested as medications for cocaine dependence. The present experiments examined the effect of acute and repeated administration of drugs with varying intrinsic efficacy at D2/D3 receptors on the relative reinforcing strength of cocaine. Use of socially housed cynomolgus monkeys permitted the assessment of ...
Dbouk Hashem A HA Department of Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, NY 10461, - - 2012
Synergistic activation by heterotrimeric guanine nucleotide-binding protein (G protein)-coupled receptors (GPCRs) and receptor tyrosine kinases distinguishes p110β from other class IA phosphoinositide 3-kinases (PI3Ks). Activation of p110β is specifically implicated in various physiological and pathophysiological processes, such as the growth of tumors deficient in phosphatase and tensin homolog deleted from ...
Okubo Shuichi S Department of Neurosurgery, University of Michigan, Ann Arbor, MI 48109-2200, - - 2013
Hydrocephalus is an important complication of subarachnoid hemorrhage (SAH). We investigated the occurrence of acute hydrocephalus in a rat SAH model. SAH was induced by endovascular perforation in adult male Sprague-Dawley rats (n=36). Sham rats (n=8) underwent the same procedure without perforation. MRI was performed 24 hours after SAH and ...
Li Zhifeng - - 2012
A highly sensitive one-step real-time RT-PCR method using a minor-groove-binding (MGB) probe was developed for detection and quantitation of severe febrile with thrombocytopenia syndrome virus (SFTSV). The assay could discriminate SFTSV infection from other related viral diseases in human with a minimum detection limit of 10 viral RNA copies/µl and ...
Peng Guo-Ji - - 2012
Macrocyclic PKS-NRPS hybrid metabolites represent a unique family of natural products mainly from bacteria with broad and outstanding biological activities. However, their distribu-tion in fungi has rarely been reported, and few work has been reported regarding to their nematocidal activity. Here we describe an unprecedented class of PKS-NRPS hybrid metabolites ...
Castarlenas Ricardo - - 2012
The hydrothiolation of unsaturated carbon-carbon bonds is a practical and atom-economical approach for the incorporation of sulfur into organic frameworks. In recent years, we have witnessed the development of a range of transition-metal-based catalytic systems for the control of the regio- and stereoselectivity. In this Minireview we highlight the mechanistic ...
Jiang Peng - - 2012
The structure and magnetic properties of epitaxial (Ce(x)Sr(1-x))(Ti(0.6)Fe(0.4))O(3-δ) (x = 0, 0.1, 0.2 and 0.3) and (La(x)Sr(1-x))(Ti(0.6)Fe(0.4))O(3-δ) (x = 0, 0.1, 0.2, 0.3 and 0.4) perovskite-structure thin films deposited by pulsed laser deposition on (LaAlO(3))(0.3)(Sr(2)AlTaO(6))(0.7) (LSAT) substrates are reported. Both La and Ce ions showed a dominant 3+ valence state ...
Ball Zachary T - - 2012
Chemists have long been fascinated by metalloenzymes and their chemistry. Because enzymes are essential for biological processes and to life itself, they present a key to understanding the world around us. At the same time, if chemists could harness the reactivity and selectivity of enzymes in designed transition-metal catalysts, we ...
Yue Hao - - 2012
Surface desorption atmospheric pressure chemical ionization mass spectrometry was developed as a rapid online detection technology for the chemical fingerprints of ginseng products without any sample pretreatment. More than 20 ginsenosides were detected in the ginseng tissue and identified by their tandem mass spectrometry. Data were well matched with their ...
Aeppli Christoph - - 2012
The widespread use chlorinated phenols (CPs) as a wood preservative has led to numerous contaminated sawmill sites. However, it remains challenging to assess the extent of in situ degradation of CPs. We evaluated the use of compound specific chlorine and carbon isotope analysis (Cl- and C-CSIA) to assess CP biotransformation. ...
Thomas Lily - - 2012
Medical errors continue to occur despite multiple strategies devised for their prevention. Although many safety initiatives lead to improvement, they are often short lived and unsustainable. Our goal was to build a culture of patient safety within a structure that optimised teamwork and ongoing engagement of the healthcare team. Teamwork ...
Trelease Robert B - - 2012
Web deployable anatomical simulations or "virtual reality learning objects" can easily be produced with QuickTime VR software, but their use for online and mobile learning is being limited by the declining support for web browser plug-ins for personal computers and unavailability on popular mobile devices like Apple iPad and Android ...
Muller Olivier - - 2012
BACKGROUND: TO QUANTIFY THE CHANGES IN ARTERIAL DIMENSIONS AFTER THE ACUTE CHANGES IN PRESSURE ASSOCIATED WITH PERCUTANEOUS CORONARY INTERVENTION (PCI).METHODS AND RESULTS: FORTY-EIGHT PATIENTS WITH ONE ANGIOGRAPHICALLY MODERATE-TO-SEVERE STENOSIS WERE INCLUDED IN THE STUDY. THE PRESSURE PROXIMAL AND DISTAL TO THE STENOSIS AND THE ARTERIAL DIAMETER PROXIMAL AND DISTAL TO ...
Mulligan Anna Marie AM Keenan Research Centre, Li Ka Shing Knowledge Institute of St. Michael's Hospital, University of Toronto, Ontario, - - 2013
Breast carcinomas, including basal and hereditary cases, often present with a prominent tumoral lymphocytic infiltrate. Chemokines could play a role in attracting these cells and contribute to tumor progression. We explored tumoral expression of CXCL10 and determined the relationship between CXCL10 and lymphocytic infiltrate in a cohort of breast cancers. ...
Mardani Mohammad Ali - - 2012
Background and aim:Microtia is one of the forms of ear loss and deformity. A prosthesis that is simple to apply, and which has adequate suspension and acceptable aesthetics, can be useful in the rehabilitation of patients with this deficit and can improve the social and psychological effects of patients with ...
Saxena Roli - - 2012
The present study evaluated any possible association among Interleukin-1-beta (IL-1B)-511 and IL-1 receptor antagonist (IL-1RN) variable number tandem-repeat (VNTR) genotypes, haplotypes, and IL-1B expression with risk for hepatitis B virus-related hepatocellular carcinoma (HBV-HCC) development in India. For this, 406 subjects (153 controls, 67 inactive HBV-carriers, 65 patients with chronic-active HBV, ...
Kulminski Alexander M AM Center for Population Health and Aging, Duke University, Box 90408, Trent Hall, Room 002, Durham, NC 27708, USA. - - 2013
This study focuses on the participants of the Long Life Family Study to elucidate whether biogenetic mechanisms underlying relationships among heritable complex phenotypes in parents function in the same way for the same phenotypes in their children. Our results reveal 3 characteristic groups of relationships among phenotypes in parents and ...
Jenista Elizabeth R ER Duke Cardiovascular Magnetic Resonance Center, Duke University Medical Center, Durham, North Carolina, - - 2013
A versatile method for generating T2 -weighting is a T2 -preparation module, which has been used successfully for cardiac imaging at 1.5T. Although it has been applied at 3T, higher fields (B0 ≥ 3T) can degrade B0 and B1 homogeneity and result in nonuniform magnetization preparation. For cardiac imaging, blood ...
Roberts D C - - 2012
This review summarizes the literature regarding venous thromboembolism and examines the prophylaxis guidelines with relation to hand, wrist and elbow surgery. We performed an extensive literature search identifying any relevant case reports or outcome studies. Of 680 potential articles, only four contained data relevant to thrombosis after elbow, wrist and ...
Denichoux Aurélien - - 2012
Reaction of dialkylzincs with lithiated acetylenic epoxides is described to give zincates that undergo a three-carbon homologation reaction by an anti-SN2' pathway. This reaction occurs with the transfer of an alkyl or a silyl group affording allenylzinc intermediates. Allenic and/or homopropargylic alcohols are obtained upon hydrolysis. Quenching the reaction mixture ...
Kenny Amanda - - 2012
This study in Victoria, Australia examined issues that rural nurses face in the provision of psychosocial care. Researchers, across a diversity of fields, have argued that psychosocial care is inadequate. Current knowledge of psychosocial care in rural areas is limited, despite the centrality of nurses in the provision of this ...
Finlay Margaret - - 2012
ABSTRACT: Bovine papillomavirus type 1 infects not only cattle but also equids and is a causative factor in the pathogenesis of commonly occurring equine sarcoid tumours. Whilst treatment of sarcoids is notoriously difficult, cisplatin has been shown to be one of the most effective treatment strategies for sarcoids. In this ...
Ma Wei - - 2012
By infusing a perfluoropolyether lubricating liquid into a nano-textured alumina gel film that was modified with perfluoroalkylphosphonic acid, an omniphobic coating with low hysteresis for both polar and non-polar liquids was prepared.
Bell Elizabeth M EM Department of Botany and Plant Sciences, Center for Plant Cell Biology, University of California, Riverside, CA 92521, - - 2012
Leaves and flowers begin life as outgrowths from the edges of shoot apical meristems. Stem cell divisions in the meristem center replenish cells that are incorporated into organ primordia at the meristem periphery and leave the meristem. Organ boundaries, regions of limited growth that separate forming organs from the meristem, ...
Kamath Ganesh V - - 2012
BACKGROUND:Bankart repair with multiple anchor holes concentrated in the anterior-inferior glenoid may contribute to glenoid weakening and potentially may induce glenoid failure. PURPOSE:To compare the biomechanical strength of a Bankart repair construct that used 3 single-loaded suture anchors versus a repair construct that used 2 double-loaded suture anchors. STUDY DESIGN:Comparative ...
Milazzo Mary L - - 2012
Abstract A total of 3941 rodents were captured during a 46-month prospective (mark-recapture) study on the ecology of Catarina virus in southern Texas. Antibody reactive against Catarina virus was found in 73 (11.9%) of 611 southern plains woodrats (Neotoma micropus) and none of 3330 other rodents; strains of Catarina virus ...
Musters A M - - 2012
BACKGROUND: Supportive care is regularly offered to women with recurrent miscarriages (RMs). Their preferences for supportive care in their next pregnancy have been identified by qualitative research. The aim of this study was to quantify these supportive care preferences and identify women's characteristics that are associated with a higher or ...
Hamdani Nazha - - 2012
AIMS: Heart failure with preserved ejection fraction (HFpEF) is a major cause of morbidity and mortality. Key alterations in HFpEF include increased left ventricular (LV) stiffness and abnormal relaxation. We hypothesized that myofilament protein phosphorylation and function are deranged in experimental HFpEF vs. normal myocardium. Such alterations may involve the ...
Yap Kok Hooi KH Cardiothoracic Surgical Unit, Wythenshawe Hospital, Manchester, UK. - - 2013
A best evidence topic in cardiac surgery was written according to a structured protocol. The question addressed was: 'Is porcine or bovine valve better for aortic valve replacement?' Altogether, 562 papers were found using the reported search, of which 15 represented the best evidence to answer the question. All papers ...
Wittich Christopher M - - 2012
Improving professional attitudes and behaviors requires critical self reflection. Research on reflection is necessary to understand professionalism among medical students. The aims of this prospective validation study at the Mayo Medical School and Cleveland Clinic Lerner College of Medicine were: (1) to develop and validate a new instrument for measuring ...
Krieger Jonathan R JR Department of Medical Biophysics, University of Toronto, Toronto, Ontario, M5G 2M9, - - 2013
Numb is an endocytic adaptor protein that regulates the endocytosis and trafficking of transmembrane receptors including Notch, E-cadherin, and integrins. Vertebrate Numb is alternatively spliced at exons 3 and 9 to give rise to four protein isoforms. Expression of these isoforms varies at different developmental stages, and although the function ...
Mandl P - - 2012
OBJECTIVES: To evaluate the metrological properties of composite disease activity indices in rheumatoid arthritis (RA), utilizing information derived from clinical, grey-scale (GS) and Power Doppler (PD) ultrasound examination. To assess the classification of patients according to disease activity using such indices. METHODS: This ancillary study utilized data from a prospective, ...
Vaartjes Ilonca - - 2012
BACKGROUND AND PURPOSE: In Western Europe, mortality from ischemic stroke (IS) has declined over several decades. Age-sex-specific IS mortality, IS incidence, 30-day case fatality, and 1-year mortality after hospital admission are essential for explaining recent trends in IS mortality in the new millennium. METHODS: Data for all IS deaths (1980-2010) ...
< 9 10 11 12 13 14 15 16 17 18 19 >