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Results 551 - 600 of 2635
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Kauffmann Matthias - - 2012
Background Locally advanced (T4) non-small cell lung cancer (NSCLC) is principally amenable to surgery. For radical resection of cardiovascular structures, extracorporeal circulation (ECC) may be required. Tumor dissemination is a concern in this situation. In this study, we evaluate the long-term results of T4 NSCLC surgery with ECC and compare them ...
Chen Catherine Z - - 2012
The relaxin hormone is involved in a variety of biological functions, including female reproduction and parturition, as well as regulation of cardiovascular, renal, pulmonary, and hepatic functions. It regulates extracellular matrix remodeling, cell invasiveness, proliferation, differentiation, and overall tissue homeostasis. The G protein-coupled receptor (GPCR) relaxin family receptor 1 (RXFP1) ...
Cubilla Marisa A - - 2012
Purpose. Glucocorticoids are best known by their protective effect on retinal photoreceptor damage. However, they could also be involved in photoreceptor homeostasis under basal, non-stressful conditions. Therefore, we aimed to study glucocorticoid-induced changes of survival-related molecules in male mice retinas under standard illumination conditions (12 h light, ≤ 60 lux/12 ...
Jalan Abhishek A - - 2012
Control over composition and register of the peptide chains in AAB-type collagen mimetic heterotrimers is critical in developing systems that show fidelity to native collagen. However, their design is challenging due to the eight competing states possible for a mixture of non-identical peptides A and B. Interpeptide salt-bridges have been ...
Morales-Múnera C - - 2012
Palmoplantar pustulosis is characterized by sterile pustules with hyperkeratosis, erythema, scaling, and fissuring on the palms and soles.(1) It has been reported to be more frequent in middle-aged women, smokers, and diabetic patients(2) , and it is increasingly reported as a paradoxical reaction to antitumor necrosis factor alpha (anti-TNF) biological ...
Zhu L M - - 2012
An all-organic rechargeable battery is realized by use of polyparaphenylene as both cathode- and anode-active material. This new battery can operate at a high voltage of 3.0 V with fairly high capacity, offering a renewable and cheaper alternative to conventional batteries.
Liu Weibing - - 2012
A sequential oxidative tandem cyclization reaction mediated by a combination of (diacetoxyiodo)benzene (DIB) with zinc oxide (ZnO) is presented for the synthesis of 5-methyl-2-phenylisoxazol-3(2H)-ones from β-ketobutylanilides. A variety of β-ketobutylanilide compounds were used in this approach, and a wide range of functionalized 5-methylisoxazol-3(2H)-ones were obtained in good to excellent yields.
Visram Hasina - - 2012
Abstract Objective: To explore the relationship between overweight and obesity and breastfeeding behaviours, a cohort study was conducted among 22,131 women who delivered in Ontario hospitals between April 1 2008 and March 31 2010. Methods: Data regarding maternal characteristics, maternal body mass index (BMI), infant characteristics, and breastfeeding practices was ...
Chan Chien Aun - - 2012
Internet traffic has grown rapidly in recent years and is expected to continue to expand significantly over the next decade. Consequently, the resulting greenhouse gas (GHG) emissions of telecommunications service-supporting infrastructure have become an important issue. In this study, we develop a set of models for assessing the use-phase power ...
Lee T H - - 2012
Background and study aims: Endoscopic bilateral drainage for inoperable malignant hilar biliary strictures (HBS) using metal stents is considered to be technically difficult. Furthermore, endoscopic revision of bilateral stenting after occlusion can be challenging. This study was performed to evaluate the long-term efficacy of endoscopic bilateral stent-in-stent placement of cross-wired ...
Stabile Laura P LP Departments of Pharmacology & Chemical Biology and Otolaryngology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, - - 2013
Strategies to inhibit the EGF receptor (EGFR) using the tyrosine kinase inhibitor erlotinib have been associated with limited clinical efficacy in head and neck squamous cell carcinoma (HNSCC). Co-activation of alternative kinases may contribute to erlotinib resistance. We generated HNSCC cells expressing dominant-active c-Src (DA-Src) to determine the contribution of ...
Caron Joachim - - 2012
A series of new lipid prodrugs of paclitaxel, which can be formulated as nanoassemblies, are described. These prodrugs which are designed to overcome the limitations due to the systemic toxicity and low water solubility of paclitaxel consist of a squalene chain bound to the 2'-OH of paclitaxel through a 1,4-cis,cis-dienic ...
Majumdar Kaushik - - 2012
In lymphoplasmacyte-rich meningioma (LRM) meningothelial whorls are overshadowed by exuberant infiltration by lymphocytes, plasma cells and few histiocytes. Hence, lesions with lymphoplasmacytic proliferation form the histological differentials. We describe the, to the best of our knowledge, first case of LRM with occasiona emperipolesis, creating a diagnostic dilemma with Rosai-Dorfman disease ...
Naik Deepak N - - 2012
AIMS: The study aimed to discover Quorum Sensing (QS) inhibitors from marine sponge derived actinomycetes and analyse its inhibitory activities against QS mediated virulence factors in Pseudomonas aeruginosa. METHODS AND RESULTS: 72 actinomycetes isolated from marine invertebrates collected from the western coast of India were screened against the QS indicator ...
Zhu Motao M Department of Epidemiology and Injury Control Research Center, West Virginia University, Morgantown, WV 26506-9151, USA. - - 2013
Graduated Driver Licensing (GDL) has been implemented in Australia, Canada, New Zealand, USA and Israel. We conducted an exploratory summary of available data to estimate whether GDL effects varied with age. We searched MEDLINE and other sources from 1991-2011. GDL evaluation studies with crashes resulting in injuries or deaths were ...
Arora Kamaldeep - - 2012
A term male infant born by normal vaginal delivery was diagnosed to have holoprosencephaly on antenatal ultrasound, which was confirmed by postnatal MRI as alobar holoprosencephaly figure). Clinical examination revealed no microcephaly or dysmorphism, except flat nasal bridge.
Tian Ye - - 2012
Mohammed Ben Alhocain, in an Arab manuscript of the 10th century, stated that the principal object of the theory of rational right triangles is to find a square that when increased or diminished by a certain number, m becomes a square [Dickson LE (1971) History of the Theory of Numbers ...
Yuan Chun-Mao - - 2012
Eight new limonoids, khayseneganins A-H (1-8), and 31 known limonoids were isolated from the leaves and twigs of Khaya senegalensis. The structures of the new compounds were elucidated by 2D-NMR spectroscopy and mass spectrometry, and the absolute configuration of 1 was determined by the CD exciton chirality method. Compounds 9, ...
Bhadaniya Amit R - - 2012
The present study was carried out to evaluate the effects of exposure at different doses of acephate on hematology, blood biochemistry, oxidative stress and immune system of Wistar rats. The experiment was carried out on 40 Wistar rats, which were divided in four groups. Animals of the three treatment groups ...
Festini Sara B - - 2012
Names are more difficult to remember than other personal information such as occupations. The current research examined the influence of assigned point value on memory and metamemory judgements for names and occupations to determine whether incentive can improve recall of proper names. In Experiment 1 participants studied face-name and face-occupation ...
Pastorello Elide A - - 2012
Fennel allergy has been rarely reported and the association with peach allergy has never been described. Our aim was to: i)study the correlation between symptoms severity to peach and fennel, ii)identify fennel allergens and the role of rPru p3 antibodies in severe reactions to fennel. In 148 pts with peach ...
Moulton Patricia L - - 2012
With the passage of the Affordable Care Act and the development of a National Workforce Commission, multiple entities have increased their interest in collecting standardized health care workforce data at the state and national levels. In a tight budget environment, developing data sets which collect the minimum needed information that ...
Busch Annegret P - - 2012
Protection of biological compounds, e.g. enzymes, viruses or even whole cells, against degradation is very important for many applications. Embedding of such compounds into polymer matrices is a straightforward common method. However, in biotechnology and medicine there is a great interest to prepare micro- and nanosized shells around the biocomponents ...
Liang Jen-Feng - - 2012
ObjectiveTo investigate whether cluster headache (CH) was a risk factor for depression in a nationwide population-based follow-up study.BackgroundThere are few studies about the relationship between CH and depression, and prior research has been limited by cross-sectional studies or small sample sizes.MethodsWe identified 673 CH patients from the Taiwan National Health ...
Nowosielski Krzysztof - - 2012
Introduction.  Unlike male sexual function, which is relatively easy to assess, female sexual function is still a diagnostic challenge. Although numerous new measurements for female sexual dysfunction (FSD) have recently been developed, the Female Sexual Function Index (FSFI) remains the gold standard for screening. It has been validated in more ...
Reed S J - - 2012
BACKGROUND: /st>Positron emission tomography studies in human subjects show that propofol-induced unconsciousness in humans is associated with a reduction in thalamic blood flow, suggesting that anaesthesia is associated with impairment of thalamic function. A recent study showed that antagonism of propofol-induced unconsciousness by the anticholinesterase physostigmine is associated with a ...
Munk T - - 2012
BACKGROUND: Undernutrition and insufficient energy and protein intake is a common problem in hospitalised patients. The aim of this pilot study was to investigate whether a novel hospital menu would be an effective strategy for increasing nutritional intake in patients at nutritional risk. METHODS: A historically controlled intervention pilot study ...
Everard Mark - - 2012
A narrow technocentric focus on a few favoured ecosystem services (generally provisioning services) has led to ecosystem degradation globally, including catchment systems and their capacities to support human wellbeing. Increasing recognition of the multiple benefits provided by ecosystems is slowly being translated into policy and some areas of practice, though ...
Kaski Diego - - 2012
A 45-year-old woman on etanercept for rheumatoid arthritis presented with an acute right Bell palsy and auricular herpetic rash (Ramsey Hunt syndrome). Despite IV acyclovir, she developed headache, vertigo, severe vomiting, and evidence of a right peripheral audiovestibular loss (figure 1, A and B, video 1 on the Neurology® Web ...
Hong Bo - - 2012
Rauvolfia verticillata (Lour.) Baill. (also called Luofumu in Chinese) is commonly used in traditional Chinese medicine for lowering blood pressure. In this study, a high-performance liquid chromatography assay using ultraviolet detection is described for the simultaneous measurement of the five bioactive indole alkaloids (sarpagine, yohimbine, ajmaline, ajmalicine and reserpine) in ...
Gold Michael R MR Medical University of South Carolina, Charleston, South Carolina 29425-5920, USA. - - 2013
All modern defibrillation systems use biphasic shock waveforms. Typically a fixed tilt waveform is used for implantable defibrillators (ICDs), but a tuned waveform with duration based on shock impedance may be superior based on theoretical calculations. The objective of this study was to compare defibrillation efficacy of fixed tilt and ...
Baster PaweĊ‚ P Department of Plant Systems Biology, VIB and Department of Plant Biotechnology and Genetics, Ghent University, Gent, - - 2013
The distribution of the phytohormone auxin regulates many aspects of plant development including growth response to gravity. Gravitropic root curvature involves coordinated and asymmetric cell elongation between the lower and upper side of the root, mediated by differential cellular auxin levels. The asymmetry in the auxin distribution is established and ...
Gao Qiang - - 2012
In this paper, we report a simple approach for fabricating scalable flexible tactile sensors using a nanofiber assembly of regioregular poly(3-hexylthiophene) (P3HT). Uniform P3HT nanofibers are obtained through a continuous electrospinning process using a homogeneous solution of high-molecular-weight P3HT. The P3HT nanofibers are oriented by collecting them on a rotating ...
Lopez Tony - - 2012
A 16-year-old girl is admitted with a paracetamol overdose, but refuses treatment. This article explores the legal, ethical and practical aspects of this case, which led ultimately to an application to the court for a judicial order.
Sarvottam Kumar - - 2012
Abstract Objective: To investigate the effect of a short-term yoga-based lifestyle intervention on risk factors for cardiovascular disease (CVD) and markers of inflammation and endothelial function in overweight and obese men. Design: Nonrandomized prospective lifestyle intervention study with pre-post design. Setting and location: Integral Health Clinic, an outpatient facility providing ...
Drechsler Christiane - - 2012
BackgroundSudden cardiac death is common and accounts largely for the excess mortality of patients on maintenance dialysis. It is unknown whether aldosterone and cortisol increase the incidence of sudden cardiac death in dialysis patients.Methods and resultsWe analysed data from 1255 diabetic haemodialysis patients participating in the German Diabetes and Dialysis ...
Gad Shayne C - - 2012
Gold nanoshells (155 nm in diameter with a coating of polyethylene glycol 5000) were evaluated for preclinical biocompatibility, toxicity, and biodistribution as part of a program to develop an injectable device for use in the photothermal ablation of tumors. The evaluation started with a complete good laboratory practice (GLP) compliant ...
Harris Ruth B S RB Department of Physiology, Georgia Health Sciences University, Augusta, GA 30912, USA. - - 2013
We previously reported that peripheral leptin infusions in chronically decrebrate rats, in which the forebrain is neurally isolated from the hindbrain, increased body fat and decreased energy expenditure. Any central leptin response in decerebrate rats would depend upon the hindbrain. Here, we tested whether selective activation of hindbrain leptin receptors ...
Palladino Pasquale - - 2012
A novel method for cleaving from resin and removing acid-labile protecting groups for the Fmoc solid-phase peptide synthesis is described. 0.1 N HCl in hexafluoroisopropanol or trifluoroethanol cleanly and rapidly removes the tert-butyl ester and ether, Boc, trityl, and Pbf groups and cleaves the common resin linkers: Wang, HMPA, Rink ...
Feng Bao-Hua - - 2012
A stable inherited rice spotted-leaf mutant HM47 derived from an EMS-induced IR64 mutant bank was identified. The mutant expressed hypersensitive response (HR)-like symptoms throughout its whole life from the first leaf to the flag leaf, without pathogen invasion. Initiation of the lesions was induced by light under natural summer field ...
Zhu Xiaozhang - - 2012
We demonstrate that a carbon-bridged phenylenevinylene (CPV)-linked dye serves as a novel and efficient sensitizer for dye-sensitized solar cells. The cells show IPCE values of greater than 90%, PCEs of up to 7.12%, and high open circuit voltages reaching close to 0.8 V based on the iodide/triiodide electrolyte.
Oberringer M - - 2012
Despite the regenerative capability of bone, treatment of large defects often requires bone grafts. The challenge for bone grafting is to establish rapid and sufficient vascularization. Three-dimensional (3D) multicellular spheroids consisting of the relevant cell types can be used as "mini tissues" to study the complexity of angiogenesis. We investigated ...
Keith Daniel J - - 2012
Abstract Objectives: To determine whether a text message reduces the severity of patient self-reported levels of pain and anxiety following initial placement of orthodontic appliances. Materials and Methods: Thirty-nine orthodontic patients were randomly assigned to one of two groups and matched for age, gender, and bracket type (self-ligating vs conventional). ...
Tseng Ying-Jung - - 2012
Abstract Objective: This report of one case illustrates the potential effect of acupuncture therapy in addition to Western medicine for regaining postoperative consciousness in patients with traumatic brain injury (TBI). Clinical features: A 65-year-old man experienced a TBI after being involved in a motor vehicle accident. His initial Glasgow Coma ...
Amabile Giovanni G Harvard Medical School, Boston, MA 02115, - - 2013
Lineage-restricted cells can be reprogrammed to a pluripotent state known as induced pluripotent stem (iPS) cells through overexpression of 4 transcription factors. iPS cells are similar to human embryonic stem (hES) cells and have the same ability to generate all the cells of the human body, including blood cells. However, ...
Pradhan Mandakini - - 2012
Abstract Objective: To find out the prevalence of thyroid peroxidase antibodies (TPO) in pregnant women with hypothyroidism and to analyse its effect on pregnancy outcome. Methods: The prospective study was conducted on well controlled hypothyroid pregnant patients attending the antenatal clinic at Sanjay Gandhi Post Graduate Institute of Medical Sciences, ...
Harris Charles C Gladstone Institute for Cardiovascular Disease, San Francisco, CA, USA. - - 2013
Glucocorticoids are extremely effective anti-inflammatory therapies, but their clinical use is limited due to severe side effects, including osteoporosis, muscle wasting, fat redistribution, and skin thinning. Here we use heavy water labeling and mass spectrometry to measure fluxes through metabolic pathways impacted by glucocorticoids. We combine these methods with measurements ...
Misslitz Holger - - 2012
Microfiber-nanofiber composites are prepared by in situ formation of supramolecular nanofiber webs based on 1,3,5-benzenetricarboxamides in polymer nonwoven scaffolds. The supramolecular nanofibers are strongly fixed to nonwoven microfibers. These composites are sufficiently stable to be suited for air filtration applications.
van Uitert Evelyne M - - 2012
Worldwide periconceptional folic acid supplement use is recommended to prevent neural tube defects. This also stimulated research on maternal folate status in association with fetal growth, an important predictor of perinatal and future development and health. We provide an overview of literature on associations between maternal folate status during pregnancy ...
Krishnaji Sreevidhya Tarakkad ST Department of Chemistry, Tufts University, Medford, MA 02155, - - 2013
Heavy metals constitute a source of environmental pollution. Here, novel functional hybrid biomaterials for specific interactions with heavy metals are designed by bioengineering consensus sequence repeats from spider silk of Nephila clavipes with repeats of a uranium peptide recognition motif from a mutated 33-residue of calmodulin protein from Paramecium tetraurelia. ...
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