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Faisal Mohammad - - 2012
Synseed technology is one of the most important applications of plant biotechnology for in vitro conservation and regeneration of medicinal and aromatic plants. In the present investigation, synseeds of Rauvolfia tetraphylla were produced using in vitro-proliferated shoots upon complexation of 3 % sodium alginate and 100 mM CaCl(2). The encapsulated buds were ...
Hawkins Clifford Matthew - - 2012
Transarterial radioembolisation with yttrium-90 (TARE-Y90), a catheter-directed therapy, has been used extensively in adults to treat primary and secondary hepatic malignancies. To our knowledge, the use of this palliative technique has not been described in children. We present two children with unresectable hepatocellular carcinoma (HCC) treated with TARE-Y90.
Soangra Rahul R School of Biomedical Engineering and Sciences, Virginia Tech Wake Forest University, Blacksburg, VA 24061, - - 2013
Patients with end stage renal diseases (ESRD) undergoing hemodialysis (HD) have high morbidity and mortality due to multiple causes; one of which is dramatically higher fall rates than the general population. In spite of the multiple efforts aiming to decrease the high mortality and improve quality of life in ESRD ...
Baes C - - 2012
Genetically reducing boar taint using low-taint lines is considered the most sustainable and economic long-term alternative to surgical castration of male pigs. Owing to the high heritability of the main boar taint components (androstenone, skatole and indole), breeding is an excellent tool for reducing the number of tainted carcasses. To ...
Gintis Herbert - - 2012
McCullough et al.'s target article is a psychological version of the reputation models pioneered by biologist Robert Trivers (1971) and economist Robert Frank (1988). The authors, like Trivers and Frank, offer an implausible explanation of the fact that revenge is common even when there are no possible reputational effects. I ...
Sun Huijiao - - 2012
Potassium ions play diverse roles in biological processes, and abnormal K(+) levels are the hallmarks of diseases. However, the potential clinical application of the developed DNA-based K(+) sensors remains a challenge due to the presence of Pb(2+) in blood samples. In this contribution, a novel colorimetric potassium sensing assay that ...
Wesley Carlos Knute - - 2012
Abstract Local administration of corticosteroids has been demonstrated to have both beneficial and detrimental effects on wound healing. The advantages of limiting localized edema must be weighed against corticosteroids' disadvantageous inhibition of the normal growth factor profile production that is essential for would healing. A single-center prospective, randomized, controlled, single-blind ...
Barclay Pat - - 2012
The target article's important point is easily misunderstood to claim that all revenge is adaptive. Revenge and forgiveness can overstretch (or understretch) the bounds of utility due to misperceptions, minimization of costly errors, a breakdown within our evolved revenge systems, or natural genetic and developmental variation. Together, these factors can ...
Subathra M - - 2012
Microscopic agglutination test (MAT) is the standard method for the diagnosis of leptospirosis, which is laborious and the interpretation of the results is subjective. The present work describes the use of recombinant-based IgG ELISA for the serodiagnosis of leptospirosis. We used recombinant outer membrane protein OmpL1 as an antigen for ...
McAnena L - - 2012
INTRODUCTION: A case of an 11-year-old boy presenting with a two-week history of a red, irritated right eye after handling a Chilean Rose Tarantula at an exotic pet exhibition. Examination revealed innumerable microscopic hairs embedded at all levels of the cornea. He was commenced on steroid drops with subjective and ...
Chao Yuehui - - 2012
In Arabidopsis, allelic variation at the FRIGIDA (FRI) locus is a major determinant of natural variation in flowering time. We have identified a FRIGIDA like protein gene, MsFRI-L, with unknown function from Medicago sativa L. Expression of MsFRI-L was increased in wild alfalfa under continuous cold conditions and the gene ...
Ormitti Francesca - - 2012
Unilateral absence of a parotid gland at the expected location is an extremely rare condition with only a few cases reported in the medical literature and, to our knowledge, never previously described in association with CHARGE syndrome (Coloboma of the eye, Heart defects, Atresia of the choanae, Retardation of growth ...
Gili Pablo - - 2012
BACKGROUND: Evaluation of the efficacy of monochromatic photography of the ocular fundus in differentiating optic nerve head drusen (ONHD) and optic disc oedema (ODE). METHODS: Sixty-six patients with ONHD, 31 patients with ODE and 70 healthy subjects were studied. Colour and monochromatic fundus photography with different filters (green, red and ...
Schramm Elizabeth C EC Department of Crop and Soil Sciences, Washington State University, Pullman, WA 99164-6420, - - 2013
As a strategy to increase the seed dormancy of soft white wheat, mutants with increased sensitivity to the plant hormone abscisic acid (ABA) were identified in mutagenized grain of soft white spring wheat "Zak". Lack of seed dormancy is correlated with increased susceptibility to preharvest sprouting in wheat, especially those ...
Konrath Sara - - 2012
We review two subjective (mis)perceptions that influence revenge and forgiveness systems. Individual differences predict more (e.g., narcissism) or less (e.g., empathy) revenge, with the opposite pattern for forgiveness. Moreover, differences in victim versus perpetrator perceptions can influence revenge and forgiveness systems, perpetuating never-ending cycles of revenge. These two examples point ...
Edwards M R - - 2012
Deficient type I interferon-β and type III interferon-λ induction by rhinoviruses has previously been reported in mild/moderate atopic asthmatic adults. No studies have yet investigated if this occurs in severe therapy resistant asthma (STRA). Here, we show that compared with non-allergic healthy control children, bronchial epithelial cells cultured ex vivo ...
Difranco Stephen A - - 2012
Mo(NMe(2))(4) and the tridentate, dipyrrolyl ligand H(2)dpma(mes) were found to form 5-coordinate Mo(NMe(2))(2)(dpma(mes)) (), which exhibits spin-crossover behaviour in solution. The complex is a ground state singlet with a barrier of 1150 cm(-1) for production of the triplet in d(8)-toluene. The complex reacts with 1,1-disubstituted hydrazines or O-benzylhydroxylamine to produce ...
White Arica - - 2012
PURPOSE: Differences in health status and behavioral risk factors may explain racial/ethnic breast cancer disparities. We examined racial/ethnic differences in health status and behaviors among female breast cancer survivors compared to females without breast cancer. METHODS: Using cross-sectional data from the 2009 Behavioral Risk Factor Surveillance System, a national state-based, ...
Schweizer Angélick - - 2012
There are currently few studies exploring doctors' personal perspectives on integrating sexuality into medical consultations. This study focuses on the views of gynaecologists on introducing, or not introducing, sexuality into their work. A total of 30 semi-structured interviews were conducted with gynaecologists in the French-speaking part of Switzerland. The thematic ...
Moriconi Pascale-Audrey - - 2012
ABSTRACT This study examines changes in the alcohol consumption of Canadians aged 55 and older from the 1990s to the 2000s and investigates whether the differences persist after controlling for the socio-demographic composition of the samples. The data included two subsamples of respondents 55 to 74 years of age from ...
Coole Carol - - 2012
Purpose More than 40 % of working age adults with stroke fail to return to work. The work context is a key factor in return to work, but little is known about the experiences of employers in supporting employees with stroke. The aim of this study was to explore return to ...
Yee Lisa D LD Department of Surgery, The Ohio State University, Columbus, OH 43210, USA. - - 2013
We previously demonstrated that lifelong feeding of diets enriched in n-3 fatty acids such as docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) significantly inhibits HER-2/neu-mediated mammary tumorigenesis in mice. Of interest is whether dietary n-3 fatty acids exert effects at early stages of mammary carcinogenesis. Seven-week-old female MMTV-HER-2/neu transgenic mice ...
Kitagawa Sayuri - - 2012
PURPOSE OF WORK: To elucidate the mechanisms of high performance by soy peptides during yeast fermentation in low temperature stress conditions and to identify a type of soy peptide that is suitable for yeast fermentation at low temperatures during brewing. The growth of a tryptophan auxotrophic yeast strain in a ...
Wallace Bret D - - 2012
Xenobiotic compounds undergo a critical range of biotransformations performed by the phase I, II, and III drug-metabolizing enzymes. The oxidation, conjugation, and transportation of potentially harmful xenobiotic and endobiotic compounds achieved by these catalytic systems are significantly regulated, at the gene expression level, by members of the nuclear receptor (NR) ...
Weichenthal Scott - - 2012
Few studies have examined indoor air quality in First Nations communities and its impact on cardiorespiratory health. To address this need, we conducted a cross-over study on a First Nations reserve in Manitoba, Canada including 37 residents in 20 homes. Each home received an electrostatic air filter and a placebo ...
Uhlmann Eric Luis - - 2012
McCullough et al.'s functionalist model of revenge is highly compatible with the person-centered approach to moral judgment, which emphasizes the adaptive manner in which social perceivers derive character information from moral acts. Evidence includes act-person dissociations in which an act is seen as less immoral than a comparison act, yet ...
Stein Dan Joseph - - 2012
Insofar as South Africa underwent a rapid transformation from apartheid to democracy, it may provide a unique laboratory for investigating aspects of revenge and forgiveness. Here we suggest that observations and data from South Africa are partially consistent with the hypotheses generated by MCullough and colleagues. At the same time, ...
Pellikaan W F - - 2012
The aim of the current study was to explore the use of the tracer 13C as an internal marker to assess feed fraction-specific digesta passage kinetics through the digestive tract of dairy cows. Knowledge on feed-specific fractional passage rates is essential to improve estimations on the extent of rumen degradation ...
Arun Babu Thirunavukkarasu - - 2012
Accidental sand aspiration is an unusual but potentially life-threatening condition in children. Sand aspiration often occurs in cases of near drowning and accidental burial in sand. The authors report a case of accidental sand aspiration in a 14-mo-old girl while she was playing with sand. Though child was symptomatic and ...
Hour Mann-Jen - - 2012
6-(N,N-Dimethylamino)-2-(naphthalene-1-yl)-4-quinazolinone (DPQZ)-induced apoptosis was accompanied by the characteristics of DNA fragmentation and phosphatidylserine externalization in human oral cancer HSC-3 cells. The IC(50) (half maximal inhibitory concentration) value of DPQZ is about 0.25 μM at 24 h. The interference in the dynamics of tubulin and cell division of DPQZ, like vinblastine (0.01 μM), has ...
Xiang Jin Yu JY Department of Biochemistry and Molecular Biophysics, Washington University in St. Louis, St. Louis, Missouri 63110, - - 2013
A general molecular mechanics (MM) model for treating aqueous Cu(2+) and Zn(2+) ions was developed based on valence bond (VB) theory and incorporated into the atomic multipole optimized energetics for biomolecular applications (AMOEBA) polarizable force field. Parameters were obtained by fitting MM energies to that computed by ab initio methods ...
Tan E - - 2012
The application of temporary sutures placed through the tarsus of the lower eyelid are well documented in the Oculoplastic and Dermatologic surgery literature. They are generally used as a suspension suture (Frost suture) to reduce the risk of ectropion due to wound contraction after reconstructive procedures involving the lower eyelid.(1-5) ...
Duncan Melanie R MR Department of Microbiology and Immunology, Meharry Medical College, Nashville, Tennessee 37208, - - 2013
In eukaryotes, proteins are imported into mitochondria via multiprotein translocases of the mitochondrial outer and inner membranes, TOM and TIM, respectively. Trypanosoma brucei, a hemoflagellated parasitic protozoan and the causative agent of African trypanosomiasis, imports about a thousand proteins into the mitochondrion; however, the mitochondrial protein import machinery in this ...
Kilch Tatiana T Department of Biophysics, Saarland University, D-66421 Homburg, - - 2013
A drop of endoplasmic reticulum Ca(2+) concentration triggers its Ca(2+) ssensor protein stromal interaction molecule 1 (STIM1) to oligomerize and accumulate within endoplasmic reticulum-plasma membrane junctions where it activates Orai1 channels, providing store-operated Ca(2+) entry. To elucidate the functional significance of N-glycosylation sites of STIM1, we created different mutations of ...
Chang Chia Min - - 2012
Using the curved arrangement of Au nanobumps, the scattering of surface plasmon waves are transformed into spots at desired locations and altitudes in three-dimensional space. The light can be modulated into desired light patterns. This work is very promising for compact plasmonic circuitry, projection, live-cell imaging, optical sensing, and holography.
Bui Eric E Center for Anxiety and Traumatic Stress Disorders, Massachusetts General Hospital, Boston, Massachusetts 02114, USA. - - 2013
Complicated grief (CG) is a bereavement-specific syndrome characterized by traumatic and separation distress lasting over 6 months. Little is known about the role of dissociation experienced during or immediately after the loss of a loved one (i.e., periloss dissociation [PLD]) in CG. The present study aimed to examine the psychometric ...
Smeets Daisy J H - - 2012
Novel word learning is reported to be problematic for children with severe language impairments (SLI). In this study, we tested electronic storybooks as a tool to support vocabulary acquisition in SLI children. In Experiment 1, 29 kindergarten SLI children heard four e-books each four times: (a) two stories were presented ...
Sira Mano - - 2012
INTRODUCTION: Orbital exenteration is a highly disfiguring procedure which, although providing local control of invasive orbital malignancy also results in marked visual, psychological and social disability. We present three consecutive total exenteration cases over 1 year where all 3, including extended exenteration defects, were repaired by primary closure by way ...
N'guessan Hartmann E - - 2012
Classical experiments show that the force required to slide liquid drops on surfaces increases with the resting time of the drop, t(rest), and reaches a plateau typically after several minutes. Here we use the centrifugal adhesion balance to show that the lateral force required to slide a water drop on ...
Urushihara Hisashi - - 2012
In response to the 2009 H1N1 influenza pandemic, the governments of Japan and the United States for the first time authorized the emergency use of unapproved drugs. In this article, we comprehensively review the different regulatory approaches of Japan and the United States, countries with advanced regulatory and healthcare systems, ...
Vogiatzoglou Anna - - 2012
ObjectiveTo investigate the cross-sectional relation between metabolic markers of vitamin B(12) status and cognitive performance, and possible effect modification by the presence of depression and apolipoprotein E (ApoE) ε4.MethodsThis is a population-based study of 1935 participants, aged 71 to 74 years, from Norway. Participants were administered a cognitive test battery, ...
El Dib Gisele - - 2012
The reaction of the OH radicals with 4-hydroxy 2-butanone was investigated in the gas-phase using an absolute rate method at room temperature and over the pressure of 10 to 330 Torr in He and air as diluent gases. The rate coefficients were measured using pulsed laser photolysis (PLP) of H2O2 ...
Takagi-Niidome Shizuka - - 2012
Presenilin 1 (PS1) comprises a catalytic subunit of γ-secretase, which is an intramembrane-cleaving protease responsible for generation of amyloid-β peptides as well as Notch cleavage, the latter being implicated in cancer. We have shown that transmembrane domains (TMDs) 1, 6, 7 and 9 of PS1 form the "catalytic pore" structure ...
Clarke Rosemary E J - - 2012
OBJECTIVE: To determine the utility of secondary stratification measures to improve the ascertainment of index cases of familial hypercholesterolaemia (FH). DESIGN: A retrospective study of genotyped index patients with Simon Broome (SB) FH. SETTING: University teaching hospital. PATIENTS: 204 patients aged 55±14 years; 36% had tendon xanthoma (TX), 21% had ...
Volk Talila T Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel. - - 2013
Striated muscles contain a tightly ordered cytoplasm in which the shape and size of the nuclei are comparable and nuclear distribution is uniform. These features were recently shown to be essential for muscle function. In an attempt to elucidate mechanisms regulating the position and shape of myonuclei, we analyzed the ...
Bhutani Nidhi N Baxter Laboratory for Stem Cell Biology, Institute for Stem Cell Biology and Regenerative Medicine, Department of Microbiology and Immunology, Stanford University, Stanford, CA 94305-5175, - - 2013
Mechanistic insights into the reprogramming of fibroblasts to induced pluripotent stem cells (iPSCs) are limited, particularly for early acting molecular regulators. Here we use an acute loss of function approach to demonstrate that activation-induced deaminase (AID) activity is necessary for the initiation of reprogramming to iPSCs. While AID is well ...
Schrader Thomas O - - 2012
Two distinct and scalable enantioselective approaches to the tricyclic indole (R)-2-(7-hydroxy-2,3-dihydro-1H-pyrrolo[1,2-a]indol-1-yl)acetate, an important synthon for a preclinical S1P(1) receptor agonist, are reported. Route 1 employs a modified version of Smith's modular 2-substituted indole synthesis as the key transformation. Route 2 involves a highly enantioselective CuH-catalyzed 1,4-hydrosilylation as the stereodefining step. ...
Toczek A - - 2012
BACKGROUND: Scaling up treatment for multidrug-resistant tuberculosis is a global health priority. However, current treatment regimens are long and associated with side effects, and default rates are consequently high. This systematic review aimed to identify strategies for reducing treatment default.METHODS: We conducted a systematic search up to May 2012 to ...
Colorado J - - 2012
This paper presents a novel bat-like unmanned aerial vehicle inspired by the morphing-wing mechanism of bats. The goal of this paper is twofold. Firstly, a modelling framework is introduced for analysing how the robot should manoeuvre by means of changing wing morphology. This allows the definition of requirements for achieving ...
Tzikas Stergios - - 2012
OBJECTIVE: To evaluate mid-regional pro-adrenomedullin (MR-proADM) and mid-regional pro-atrial natriuretic peptide (MR-proANP) as prognostic biomarkers in a representative 'real world' cohort of patients with suspected acute coronary syndrome (ACS). DESIGN: Prospective observational multicentre cohort study. SETTING: Chest pain units of three major hospitals in Germany from 2007 to 2008. PATIENTS: ...
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