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Results 401 - 450 of 4077
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Zhang Menglong - - 2012
BACKGROUND: Little information exists concerning appropriate exposure and measuring overall patient dose in pediatric digital radiography. OBJECTIVE: To establish a convenient method of appropriate exposure from target exposure index (EI) and thickness in pediatric digital radiography and estimate patient entrance-surface dose (ESD) and dose-area product (DAP) associated with chest, abdomen ...
Liu Xiaosong - - 2012
Alzheimer's disease (AD) is a progressive and complex neurodegenerative disease in which the γ-secretase-mediated amyloid-β (Aβ) pathology plays an important role. We found that a multifunctional protein, β-arrestin1, facilitated the formation of NCT/APH-1 (anterior pharynx-defective phenotype 1) precomplex and mature γ-secretase complex through its functional interaction with APH-1. Deficiency of ...
Snow Daniel D - - 2012
Analytical methods for the determination of several natural and synthetic steroids in water and solid samples were developed using liquid chromatography tandem mass spectrometry. Atmospheric pressure photoionization (APPI) in positive mode was used as the source which appeared to reduce background and interferences as compared to electrospray ionization. Toluene was ...
Zhu Xianfang - - 2012
Heavy metals concentrations in surface sediments from Miyun Reservoir were determined to evaluate the pollution and identify the sources. The average content of metals in sediments from Miyun Reservoir followed the order Al>Fe>Ti>Mn>V>Zn>Cr>Ni>Cu>Pb>As>Cd>Hg, and the most mean values were lower than the globe average shale. Heavy metals concentrations at the ...
Tiscornia G C - - 2012
Endurance training is accompanied by important adaptations in both cardiovascular and autonomic nervous systems. Previous works have shown that the main component of gap junctions in the ventricular myocardium (connexin 43 (Cx43) can be regulated by adrenergic stimulus. On the other hand, training raises vagal and decreases sympathetic tone, while ...
Nagy Andrea - - 2012
PURPOSE: The aim of the study was to compare the characteristics of ventriculosubgaleal shunts during the clinical course of posthemorrhagic and postinfectious hydrocephalus in the neonatal period. PATIENTS AND METHODS: The study comprised 102 premature babies in whom subgaleal shunt was consecutively inserted between 2006 and 2011. Seventy-two patients had ...
Kok H K - - 2012
BACKGROUND: Percutaneous interventions for renal arterial disease can be used to treat a variety of conditions including both atherosclerotic and non-atherosclerotic renal artery stenosis (RAS) as well as endovascular management of renal artery aneurysms (RAA). AIM: We sought to examine the indications, techniques and results of percutaneous renal angioplasty and ...
Tonolini Massimo - - 2013
Squamocellular anal carcinoma is increasingly diagnosed in patients with risk factors. State-of-the-art imaging with magnetic resonance imaging (MRI) using phased-array coils and volumetric multidetector computed tomography (CT) provides detailed visualisation of anal disorders, identification and extent assessment of neoplastic tissue, detection and characterisation of nodal and visceral metastases. MRI has ...
Zhang Qi - - 2012
This article provides the first detailed description and systematic evaluation of the management of otic barotrauma using modified intravenous cannulae. A 24-gauge IC cannula was modified as a tool for tympanostomy tube placement and middle ear ventilation. The medical records of 271 ears of 156 adult patients (median age 49 years) ...
Klopsch Christian - - 2012
At present, intensive investigation aims at the creation of optimal valvular prostheses. We introduced and tested the applicability and functionality of two advanced cell-plus-matrix seeding technologies, spray-assisted bioprocessing (SaBP) and laser-assisted bioprocessing (LaBP), for autologous tissue engineering (TE) of bioresorbable artificial grafts. For SaBP, human mesenchymal stem cells (HMSCs), umbilical ...
Jang Eunha - - 2012
Activated macrophages are classified into two different forms: classically activated (M1) or alternatively activated (M2) macrophages. The presence of M1/M2 phenotypic polarization has also been suggested for microglia. Here, we report that the secreted protein lipocalin 2 (LCN2) amplifies M1 polarization of activated microglia. LCN2 protein (EC(50) 1 μg/ml), but ...
Vora Avni - - 2012
Background: Synovial sarcomas are uncommon malignancies that mainly affect adolescents and young adults. Most arise from the deep soft tissues of the extremities, but they can occur in other parts of the body such as the lung. Synovial sarcomas after radiation therapy are rare, in contrast with other sarcomas, with ...
Huang Shr-Wei - - 2012
Clostridial diseases are zoonoses and are classified as soil-borne diseases. Clostridium chauvoei and Clostridium tetani cause blackleg disease and tetanus, respectively. Since bacteria and spores are re-distributed by floods and then, subsequently, contaminate soils, pastures, and water; the case numbers associated with clostridial diseases usually increase after floods. Because Taiwan ...
Mattiucci Gian Carlo - - 2012
PURPOSE: To evaluate the efficacy in terms of local control (LC) of 24 h infusion of gemcitabine plus radiotherapy after surgery for pancreatic cancer. METHODS: Weekly gemcitabine (100 mg/m(2)) was provided as a 24-hour infusion during the course of radiotherapy (50.4 Gy to the tumor, 39.6 Gy to the nodes). Patients subsequently received five ...
Kao Yu-Chien - - 2012
Fatty acid synthase (FASN) is overexpressed in many human cancers and associated with poor prognosis. However, the role of FASN in nasopharyngeal carcinoma (NPC) has not been studied. We evaluated the expression of FASN immunohistochemically in 124 NPC specimens, stratified them into two groups (FASN-high and FASN-low), and examined the ...
Nikolić Predrag - - 2012
We construct an effective topological Landau-Ginzburg theory that describes general SU(2) incompressible quantum liquids of strongly correlated particles in two spatial dimensions. This theory characterizes the fractionalization of quasiparticle quantum numbers and statistics in relation to the topological ground-state symmetries, and generalizes the Chern-Simons, BF ('background field') and hierarchical effective ...
Tan Zhi-Jian - - 2012
An alcohol/salt aqueous two-phase system (ATPS) composed of 1-propanol and (NH(4))(2)SO(4) was employed to purify anthraquinones (AQs) extracted from Aloe vera L. The main influencing system parameters such as type of alcohol, type and concentration of salt, temperature and pH were investigated in detail. Under the optimal extraction conditions, AQs ...
von Ziegler Franz - - 2012
ABSTRACT: BACKGROUND: Coronary artery calcifications (CAC) are markers of coronary atherosclerosis, but do not correlate well with stenosis severity. This study intended to evaluate clinical situations where a combined approach of coronary calcium scoring (CS) and nuclear stress test (SPECT-MPI) is useful for the detection of relevant CAD. METHODS: Patients ...
Olszewski Adam J - - 2012
PURPOSE: The aims of this study were to establish the maximum tolerated dose (MTD) of oxaliplatin in combination with fixed doses of gemcitabine, irinotecan, and 5-fluorouracil/leucovorin (G-FLIE) in solid tumors, including advanced pancreatic cancer, and to evaluate the toxicity of the regimen. METHODS: Patients with metastatic solid tumors were treated ...
Eftekhar Maryam - - 2012
PURPOSE: The incidence of poor ovarian response in controlled ovarian stimulation (COH) has been reported in 9-24 % of IVF-ET cycles. Growth hormone augments the effect of gonadotropin on granulosa and theca cells, and plays an essential role in ovarian function, including follicular development, estrogen synthesis and oocyte maturation. The aim ...
Ren Li - - 2012
Myocardial infarction is a major cause of morbidity and mortality worldwide. However, the methodological development of a spatiotemporally controllable investigation of the damage events in myocardial infarction remains challengeable. In the present study, we describe a micropillar array-aided tissue interface mimicking microfluidic device for the dynamic study of hypoxia-induced myocardial ...
Raffaelli Marco - - 2012
PURPOSE: Ipsilateral central compartment node dissection has been proposed to reduce the morbidity of prophylactic bilateral central compartment node dissection in papillary thyroid carcinoma (PTC), but it carries the risk of contralateral metastases being overlooked in approximately 25 % of patients. We aimed to verify if frozen section examination (FSE) can ...
Stephan Douglas W - - 2012
The discovery of frustrated Lewis pairs is described, as well as the ability of these intermolecular systems to react with a range of small molecules.
Ito T - - 2012
Study design:Retrospective study.Objectives:The purpose of this study was to identify the clinical factors for differentiating malignant from benign intramedullary spinal cord tumors.Setting:Niigata, Japan.Methods:We conducted a retrospective review of charts and images. Preoperative paralysis including walking ability, urinary function, magnetic resonance imaging (MRI) findings and pathological diagnosis were evaluated in 33 ...
Chevalier N - - 2012
Lipid biomarkers and their stable carbon isotopic composition, as well as 16S rRNA gene sequences, were investigated in sediment cores from active seepage zones in the Sea of Marmara (Turkey) located on the active North Anatolian Fault, to assess processes associated with methane turnover by indigenous microbial communities. Diagnostic (13) ...
Zhang Ali - - 2012
It is well known that upon stress, the level of the tumor suppressor p53 is remarkably elevated. However, despite extensive studies, the underlying mechanism involving important inter-players for stress-induced p53 regulation is still not fully understood. We present evidence that the human lincRNA-RoR (RoR) is a strong negative regulator of ...
Dickinson James - - 2012
BACKGROUND AND OBJECTIVES: Mirabegron, a selective β3-adrenoceptor agonist for the treatment of overactive bladder (OAB), is eliminated by renal and metabolic routes. The potential influence of renal or hepatic impairment on the pharmacokinetics of mirabegron was evaluated. METHODS: Two separate open-label, single-dose, parallel-group studies were conducted. Male and female subjects ...
Ohnishi Tetsuo - - 2012
Mammals express two myo-inositol monophosphatase (IMPase) genes, IMPA1/Impa1 and IMPA2/Impa2. In this study, we compared the spatial expression patterns of the two IMPase gene transcripts and proteins in mouse tissues. Results indicated discrete expression of the two IMPase genes and their protein products in various organs, including the brain. In ...
Takata Sayaka - - 2012
PURPOSE: We investigated the surface characteristics and vascular patterns of colorectal tumors according to growth type by means of magnifying narrow-band imaging (NBI). METHODS: Four hundred ninety-seven colorectal tumors larger than 10 mm (204 tubular adenomas [TAs], 199 frankly invasive intramucosal carcinomas to shallow invasive submucosal [M/SM-s] carcinomas, and 94 deeply ...
Cui Naizhong - - 2012
The ability to distinguish tumor cells from normal cells is vital to allow the immune system to selectively destroy tumor cells. In order to find an effective marker, we used enzyme-linked immunosorbent assay, immunocytochemistry, immunofluorescence, and flow cytometry to investigate the effects of heat stress on the amount of heat ...
Tanha Fateme Davari - - 2012
PURPOSE: To evaluate the efficacy of two routes of misoprostol (sublingual and vaginal) for cervical ripening before hysteroscopy. METHODS: One hundred and ten perimenopausal women who were referred to a tertiary hospital for surgical hysteroscopy enrolled in this double-blind randomized clinical trial. They were divided into two groups to receive ...
Allendorf Keera - - 2012
Scholars traditionally argued that industrialization, urbanization, and educational expansion lead to a decline in extended families and complementary rise in nuclear families. Some have suggested that such transitions are good for young married women because living in nuclear families benefits their health. However, extended families may also present advantages for ...
Koshida Mihoko - - 2012
The practices required by community and public health nurses to establish community networks mainly involve communicative competencies. Assessment through development and testing of such competencies is necessary for community and public health nurse educators and practitioners around the world to create and maintain a mutual support network. The purpose of ...
Figueredo Luciana Aguiar - - 2012
Canine cutaneous leishmaniasis by Leishmania braziliensis is a neglected, but widespread disease of dogs in South America. This paper describes clinical and hematological alterations in 17 L. braziliensis-infected dogs from Brazil. The most common hematological findings were thrombocytopenia (82.4%), anemia (70.6%), low packed cell volume (52.9%) and eosinophilia (41.2%). Twelve ...
Kurbel Sven - - 2012
This paper is based on the idea that ductal breast cancer in situ (DCIS) precedes the invasive breast cancer (invBC), although the triple-negative invBCs almost lack their DCIS precursor. Reported incidences of breast tumor types in DCIS and in invasive BCs suggest that probabilities of tumor progression might differ among ...
Liu Jinying - - 2012
A new family of isostructural Mn-Ln heterometallic clusters, [Mn(II)(2)Mn(III)(2)Ln(III)(2)(Piv)(8)(thme)(2)(H(2)tea)(2)] (H(3)thme = 1,1,1-tris(hydroxymethyl)ethane, Hpiv = pivalic acid, H(3)tea = triethanolamine, and Ln = Pr, Nd, Sm, Eu, Gd, Tb, and Dy) have been prepared by reaction of the hexanuclear manganese precursor, [Mn(6)O(2)(Piv)(10)(4-Me-Py)(2.5)(Hpiv)(1.5)], with H(3)thme, H(3)tea, and Ln(NO(3))(3)·6H(2)O under the solvothermal conditions. ...
Altelaar A F Maarten - - 2012
Next-generation sequencing allows the analysis of genomes, including those representing disease states. However, the causes of most disorders are multifactorial, and systems-level approaches, including the analysis of proteomes, are required for a more comprehensive understanding. The proteome is extremely multifaceted owing to splicing and protein modifications, and this is further ...
Luesma M José - - 2012
The primary cilium is a non-motile cilium whose structure is 9+0. It is involved in co-ordinating cellular signal transduction pathways, developmental processes and tissue homeostasis. Defects in the structure or function of the primary cilium underlie numerous human diseases, collectively termed ciliopathies. The presence of single cilia in the central ...
Wang Huili - - 2012
The interactions between room temperature ionic liquids (RTILs) and weak fluorescent chemicals still remain unclear, which hinders the complete and efficient utilization of these "green" solvents in fluorescent analyses of organic chemicals. Herein, we reported the effects of four RTILs, [C(8)MIM]BF(4,) [C(14)MIM]BF(4,) [C(8)MIM]PF(6) and [C(14)MIM]PF(6), on fluorescence behavior of 4-tert-octylphenol ...
Heng L Z - - 2012
Decades of research into the pathophysiology and management of diabetic retinopathy have revolutionized our understanding of the disease process. Diabetic retinopathy is now more accurately defined as a neurovascular rather than a microvascular disease as neurodegenerative disease precedes and coexists with microvascular changes. However, the complexities of the pathways involved ...
Kowalczyk Sarah - - 2012
GABAergic transmission is essential to brain function, and a large repertoire of GABA type A receptor (GABA(A) R) subunits is at a neuron's disposition to serve this function. The glycine receptor (GlyR)-associated protein gephyrin has been shown to be essential for the clustering of a subset of GABA(A) R. Despite ...
Marchetti Fabio - - 2012
The reactions of MoCl(5), , with small amounts of a series of carbonyl compounds in a chlorinated solvent were investigated. The chloroiminium salts [ClCH[double bond, length as m-dash]NEt(2)][Mo(O)Cl(4){O[double bond, length as m-dash]C(H)NEt(2)}], , and [Cl[upper bond 1 start]C[double bond, length as m-dash]NH(CH(2))(4)C[upper bond 1 end]H(2)][Mo(O)Cl(4){O[double bond, length as m-dash][upper bond ...
Nigam Shubha - - 2012
To evaluate the biosorption efficacy of submerged aquatic plant Hydrilla verticilata for arsenic uptake from drinking water. H. verticillata, a submerged aquatic plant was utilized successfully for arsenic uptake from aqueous solution. Batch studies with various parameters viz. pH, sorbent dose, contact time, initial metal ion concentration, and temperature were ...
Jiang Yingnan - - 2012
Plant genomes encode a large number of proteins that potentially function as immune receptors to defend against pathogen invasion. As a well-characterized receptor kinase consisting of 23 tandem leucine-rich repeats, a transmembrane domain, and a serine/threonine kinase, the rice (Oryza sativa) protein XA21 confers resistance to a broad-spectrum of Xanthomonas ...
Charoenphandhu Narattaphol - - 2012
Estrogen deficiency increases the risk of anxiety and mood disorders, presumably by deranging metabolism of the monoamine neurotransmitters and the expression of their reuptake transporters in the brain. Although estrogen-deficient individuals were also susceptible to stress, little was known regarding the effect of stress on the levels of transcripts related ...
Guidozzi F - - 2012
ABSTRACT Sleep disorders in the menopause are common. Although these disorders may be due to the menopause itself and / or the associated vasomotor symptoms, the etiology is multi factorial and includes a number of other associated conditions. They may simply arise as part of the aging process and not ...
Webb Nicholas J A - - 2012
BACKGROUND: A previous subgroup analysis of a 12-week, double-blind study demonstrated that losartan significantly lowered proteinuria versus placebo and amlodipine and was well tolerated in children (1-17 years old) with proteinuria secondary to Alport syndrome. The present subgroup analysis of the open-label, extension phase of this study assessed the long-term efficacy ...
Kurian Jessica - - 2012
Historically, the evaluation of renovascular hypertension has been accomplished by US, renal scintigraphy and digital subtraction angiography. Based on its high accuracy reported in adults renal CT angiography (CTA) with pediatric-appropriate low radiation dose techniques has become an important tool in the workup of renovascular hypertension in children. Renal CTA ...
Kikolski Steven G - - 2012
PURPOSE: To investigate the efficacy and safety of the use of transjugular intrahepatic portosystemic shunt (TIPS) creation to treat cirrhosis-related chylous collections (chylothorax and chylous ascites). METHODS: We retrospectively reviewed data from four patients treated for refractory cirrhosis-related chylous collections with TIPS at our institution over an 8 year period. RESULTS: ...
Hasegawa Koji - - 2012
Molecular interactions of the three plastoquinone electron acceptors, Q(A), Q(B), and Q(C), in photosystem II (PSII) were studied by fragment molecular orbital (FMO) calculations. Calculations at the FMO-MP2/6-31G level using PSII models deduced from the X-ray structure of the PSII complexes from Thermosynechococcus elongatus provided the binding energies of Q(A), ...
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