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Foresta C - - 2012
Background: Although vascular-calcification mechanisms are only partially understood, the role of circulating calcifying cells and non-collagenous bone matrix proteins in the bone-vascular axis is emerging. Despite that platelets represent a cellular interface between hemostasis, inflammation, and atherosclerosis and have a myeloid precursor, a possible involvement in the modulation of vascular calcification ...
Delgado-Gomez David - - 2012
There is a need to assess the psychiatric morbidity that appears as a consequence of terrorist attacks. The General Health Questionnaire (GHQ) has been used to this end, but its psychometric properties have never been evaluated in a population affected by terrorism. A sample of 891 participants included 162 direct ...
Glueck Charles J - - 2012
Abstract Objective: Prospectively assess whether metformin-diet pre-conception and throughout pregnancy would safely reduce 1(st) trimester miscarriage and improve pregnancy outcomes in women with polycystic ovary syndrome (PCOS). Research Design and Methods: In 76 PCOS women, first pregnancy miscarriage and live birth were compared before and on metformin-diet, started 6.8 months ...
Subba Reddy Basireddy Venkata - - 2012
A domino cycloisomerization/iso-Pictet-Spengler reaction of 2-(4-aminobut-1-yn-1-yl)aniline with aldehydes has been achieved using AuIPrCl (5 mol%)/AgSbF6 (10 mol%) catalytic system to produce the corresponding 1-aryl-N-tosyl-2,3,4,5-tetrahydropyrido[4,3-b] indole derivatives in good yields. This is the first report on the synthesis of tetrahydro pyrido[4,3-b]indole scaffolds through a tandem 5-endo-dig cyclization and iso-Pictect-Spengler reaction.
Matsubara Akiko - - 2012
Gastric and duodenal adenomas exhibit a significant morphological and phenotypical diversity and are classified into intestinal-type, foveolar-type, and pyloric gland adenomas. We analyzed the mutations in GNAS, KRAS, BRAF, and CTNNB1 and the expressions of mismatch repair (MMR) proteins in 80 gastric and 32 duodenal adenomas with histologically distinct subtypes ...
Ricci L - - 2012
Purpose: The aim of the present study was to perform a systematic review of the literature on the use of titanium grids for implant surgery prior and simultaneously to implant placement, and to assess the success rate of the procedure, as well as survival and success rates of implants placed ...
Marsolek Chad J - - 2012
When people describe themselves by responding to personality questionnaires, typically they endorse some items and reject others. Further, most people endorse likable traits and reject unlikeable traits. In one case, people use previously stored information about themselves to judge that a particular trait-usually likable-describes them well, and in the other, ...
Miller Holly C - - 2012
This study utilizes a novel computerized stop-distance task to examine social space preferences of young adult female and male participants (18-23 years old) who envisioned being approached by others of both sexes who were displaying different facial emotional expressions. The results showed that those displaying anger were kept furthest away, ...
Soliman Abdel-Rahman - - 2012
Here, we present evidence from laboratory experiments for the formation of nitrogen-containing complex organic ions by sequential reactions of acetylene with the pyridinium and pyrimidinium ions in the gas phase and within ionized pyridine-acetylene binary clusters. Additions of five and two acetylene molecules onto the pyridinium and pyrimidinium ions, respectively, ...
Yıldızeli Bedrettin - - 2012
Massive pulmonary hemorrhage is a potentially fatal complication of pulmonary endarterectomy. We describe a successful management in which the patient's right lower lobe bronchus was occluded with a Fogarty balloon catheter while on peripheral venoarterial extracorporeal membrane oxygenation.
Luckashenak Nancy - - 2012
Epidermal Langerhans cells (LCs) of the skin represent the prototype migratory dendritic cell (DC) subtype. In the skin, they take up Ag, migrate to the draining lymph nodes, and contribute to Ag transport and immunity. Different depletion models for LCs have revealed contrasting roles and contributions of this cell type. ...
Burns Clare L - - 2012
We explored the feasibility of providing access to specialist speech pathology services via telehealth for patients with head and neck cancer. A weekly telehealth clinic was conducted between the speech pathology departments of a tertiary hospital and a regional hospital in Queensland. Over a 5-month period, 50 telehealth sessions were ...
Bradford Natalie - - 2012
We investigated the feasibility of using Internet video calls for a double check on medication or other complex interventions being administered in the home. Seven nurses were recruited to the study and received training on using laptop and tablet computers with mobile Internet connections. The devices were taken on scheduled ...
Fasinu Pius Sedowhe - - 2012
Sutherlandia frutescens (ST) is a popular medicinal herb widely consumed in Africa by people living with HIV/AIDS. Concomitant use with antiretroviral drugs has generated concerns of herb-drug interaction. This study investigated the inhibitory effects of the crude extracts of ST on the major cytochrome P450 isozymes employing pooled human liver ...
Walsh Derek - - 2012
Viruses are obligate intracellular parasites, and their replication requires host cell functions. Although the size, composition, complexity, and functions encoded by their genomes are remarkably diverse, all viruses rely absolutely on the protein synthesis machinery of their host cells. Lacking their own translational apparatus, they must recruit cellular ribosomes in ...
Plois Markus - - 2012
High-spin hydrides: A new class of stable paramagnetic polyhydride complexes [M{Ru(μ-H)(3) (PTol(3) )(3) }(2) ] (MRu(2) , M=Cr-Ni) with an unprecedented trinuclear arrangement has been synthesized. The high-spin central 3d metal ion is sandwiched between six hydride ligands in a distorted octahedral fashion.
Lee Chang Yeol - - 2012
The "tower microneedle" (TM) via reverse drawing lithography for intravitreal injection by fabricating a long hollow microneedle on the blunt hypodermic needle: The hollow hole between the microneedle and hypodermic needle is aligned concentrically, and fifteen degree bevel angle is introduced to TM by laser cutting to achieve intravitreal injection ...
Song Zhi-Ling - - 2012
Graphene nanomaterials are typically used in biosensing applications, and they have been demonstrated as good fluorescence quenchers. While many conventional amplification platforms are available, developing new nanomaterials and establishing simple, enzyme-free and low-cost strategies for high sensitivity biosensing is still challenging. Therefore, in this work, a core-shell magnetic graphitic nanocapsule ...
Jones Patti G - - 2012
Emamectin benzoate (an avermectin chemotherapeutant administered to fish as an in-feed treatment) has been used to treat infestations of sea lice Lepeophtheirus salmonis on farmed Atlantic salmon Salmo salar in the Bay of Fundy, New Brunswick, Canada, since 1999. This retrospective study examined the effectiveness of 114 emamectin benzoate treatment ...
Mohammed Salma I - - 2012
OBJECTIVES: This study evaluated efficacy and safety of bolus doses of ziconotide (Prialt®, Eisai Limited, Hertfordshire, UK) to assess the option of continuous administration of this drug via an implanted intrathecal drug delivery system. MATERIALS AND METHODS: Twenty adults with severe chronic pain who were under consideration for intrathecal (IT) ...
Schoeppler K E - - 2012
Evidence supports the use of 12 months of cytomegalovirus prophylaxis in all at-risk lung transplants; whether cytomegalovirus serostatus can be used to further optimize this duration remains to be determined. The purpose of this retrospective study was to determine if cytomegalovirus serostatus of both donor and recipient were associated with ...
Genot Anthony J - - 2012
DNA multiplication tables: A combinatorial mechanism for DNA strand displacement shares the same structure as matrix multiplication. This system can be used to perform linear operations on DNA concentrations, such as the calculation of a weighted sum.
Longworth N - - 2012
A combined epidemiological-economic modelling approach was used to analyse strategies for highly pathogenic avian influenza (HPAI) control for the Netherlands. The modelling framework used was InterSpread Plus (ISP), a spatially based, stochastic and dynamic simulation model. A total of eight control strategies were analysed, including pre-emptive depopulation and vaccination strategies. ...
Nakamura M - - 2012
The aims of this study were to compare the detection rates of gastrointestinal follicular lymphoma lesions by video capsule endoscopy (VCE) and double-balloon endoscopy (DBE), and to determine the pathologic diagnostic yields of DBE-directed biopsies. A total of 27 consecutive patients were enrolled. No significant difference in detection rates was ...
Aase Ingunn - - 2012
The notions of interprofessional education and interprofessional teamwork have attained widespread acceptance, partly because lack of teamwork has been tentatively linked to adverse incidents in healthcare. By analyzing data from 32 educational institutions, this study identifies the status of interprofessional teamwork in all nursing and medical education in Norway. The ...
Guo Mingyu - - 2012
Hydrogel-containing core-shell capsules are useful as drug delivery vehicles for many biomedical applications, especially when release of incorporated guests can be controlled. Here, we developed a one-step organic solvent-free method to prepare such core-shell capsules using a synthetic and a natural supramolecular hydrogel, for the core and shell, respectively. A ...
Gilman Rich - - 2012
This study validates a new self-report measure, the Ostracism Experience Scale for Adolescents (OES-A). Nineteen items were tested on a sample of 876 high school seniors to assess 2 of the most common ostracism experiences: being actively excluded from the peer group and being largely ignored by others. Exploratory and ...
Lu Xiao-Yan - - 2012
Studying the essence of a syndrome has been a key challenge in the field of Chinese medicine. Until now, due to limitations of the methods available, the progress towards understanding such complicated systems has been slow. Metabonomics encompasses the dynamics, composition and analysis of metabolites, enabling the observation of changes ...
Thomas Kali S - - 2012
OBJECTIVE: To test the relationship between older Americans Act (OAA) program expenditures and the prevalence of low-care residents in nursing homes (NHs). DATA SOURCES AND COLLECTION: Two secondary data sources: State Program Reports (state expenditure data) and NH facility-level data downloaded from LTCfocUS.org for 16,030 US NHs (2000-2009). STUDY DESIGN: ...
Daniel R M - - 2012
Longitudinal studies, where data are repeatedly collected on subjects over a period, are common in medical research. When estimating the effect of a time-varying treatment or exposure on an outcome of interest measured at a later time, standard methods fail to give consistent estimators in the presence of time-varying confounders ...
Juhl Mette - - 2012
OBJECTIVE: The aim of the present study was to examine the association between occupational lifting and the risk of fetal death according to gestational age. METHODS: We used data from the Danish National Birth Cohort (1996-2002). Among 71 500 occupationally active women, 2886 experienced a fetal death. Information on lifting ...
Matsuda Atsunori - - 2012
Anionic hydrated titanate (HnTiOm: HTO) nanosheets and cationic magnesium-aluminum layered double hydroxide (Mg-Al LDH) nanosheets were electrophoretically deposited on positively and negatively charged indium tin oxide (ITO)-coated glass substrates, respectively. The HTO nanosheets and Mg-Al LDH nanosheets obtained were identified in neutral water as H2Ti4O9•nH2O with a -potential of -23mV ...
Boulon Marie-Emmanuelle - - 2012
Spotting trends: Upon going from Tb(III) to Yb(III) centers in the complexes of the DOTA(4-) ligand a reorientation of the easy axis of magnetization from perpendicular to parallel to the LnO bond of the apical water molecule is experimentally observed and theoretically predicted. Only ions with an odd number of ...
Melchardt Thomas - - 2012
Abstract Over the past decade, the treatment of patients with CLL has been improved by several new cytostatic agents and monoclonal antibodies. This development has resulted in higher response rates and more profound levels of immunosuppression than with previously used treatments. With the intrinsic immune defect of CLL, the degree ...
Lim Soo - - 2012
BACKGROUND:Metabolic syndrome (MetSyn) in children and adolescence is increasing worldwide; however, its pattern may be different between Asians and Americans. We compare the prevalence and patterns of MetSyn between American and Korean children and adolescents between roughly 1998 and 2007.METHODS:Data from the American and Korean versions of the NHANES (NHANES ...
Vohra Nasreen A - - 2012
This paper reports a single-institution experience with the use of isolated limb infusion for limb salvage in locally advanced, unresectable, recurrent limb threatening soft tissue sarcomas. Background: Locally advanced, limb threatening soft tissue sarcomas (STS) pose a significant treatment challenge. We report our experience using isolated limb infusion (ILI) in ...
Wu Judy I-Chia - - 2012
Like the larger non-planar Möbius rings, porphyrinoid aromaticity is not due primarily to the macrocyclic π conjugation of the corresponding annulene perimeters. The block-localized wavefunction (BLW) derived aromatic stabilization energies (ASE) of several porphyrinoids reveal that, on a per atom basis, the appended 6π electron heterocycles of porphyrinoids confers aromaticity ...
Laukkanen L - - 2012
Several ecological and genetic factors affect the diet specialization of insect herbivores. The evolution of specialization may be constrained by lack of genetic variation in herbivore performance on different food-plant species. By traditional view, trade-offs, that is, negative genetic correlations between the performance of the herbivores on different food-plant species ...
Pandey P R - - 2012
Upregulation of lipogenesis is a hallmark of cancer and blocking the lipogenic pathway is known to cause tumor cell death by apoptosis. However, the exact role of lipogenesis in tumor initiation is as yet poorly understood. We examined the expression profile of key lipogenic genes in clinical samples of ductal ...
Kelly Matthew A - - 2012
Vector Symbolic Architectures (VSAs) such as Holographic Reduced Representations (HRRs) are computational associative memories used by cognitive psychologists to model behavioural and neurological aspects of human memory. We present a novel analysis of the mathematics of VSAs and a novel technique for representing data in HRRs. Encoding and decoding in ...
Lai Jonathan - - 2012
Abstract Objective: To investigate the potential value of maternal serum concentration of activin-A at 30-33 weeks' gestation in the prediction of preeclampsia (PE) developing at or after 34 weeks. Methods: Serum concentrations of activin-A were measured at 11-13 and at 30-33 weeks' gestation in a case-control study of 50 cases ...
Pagonabarraga Javier - - 2012
Frontal subcortical cognitive defects are predominant in Parkinson's disease (PD). Temporal lobe dysfunction seems more relevant for progression to dementia. We aimed to study the relative importance of temporal lobe defects versus executive impairment in the progression to dementia in PD by using proton magnetic resonance spectroscopy ((1)H-MRS). The (1)H-MRS ...
Li Liming - - 2012
HMGB3 (high-mobility group box 3) is an X-linked member of a family of sequence-independent chromatin-binding proteins and functions as a universal sentinel for nucleic acid-mediated innate immune responses. The splice variant expression, promoter characterization and targeted microRNAs of the bovine HMGB3 gene were investigated to explore its expression pattern and ...
Li Yijing - - 2012
Many compounds containing a five-membered heterocyclic ring display exceptional chemical properties and versatile biological activities. In this Minireview, thiadiazoles are summarized according to their therapeutic potential, highlighting the versatility of this scaffold in medicinal chemistry. The unique properties of thiadiazoles are also discussed in relation to their potential effect on ...
Lindsten Rune - - 2012
summary Orthodontics as health care is sometimes at odds with modern marketing with its strong focus on esthetics. In this commentary, I highlight how important it is that research of orthodontic treatment as a value for the entire community is performed and published.
Szpila K - - 2012
First instars of Lucilia ampullacea Villeneuve, Lucilia caesar Linnaeus, Lucilia cuprina Weidemann, Lucilia richardsi Collin, Lucilia sericata Meigen and Lucilia silvarum Meigen (Diptera: Calliphoridae) are thoroughly documented with scanning electron microscopy images, light microscopy photographs and line drawings. The following morphological structures are documented: pseudocephalon, antennal complex, maxillary palpus, facial ...
Bagutski Viktor - - 2012
Direct electrophilic borylation using Y(2)BCl (Y(2) = Cl(2) or o-catecholato) with equimolar AlCl(3) and a tertiary amine has been applied to a wide range of arenes and heteroarenes. In situ functionalization of the sensitive ArBCl(2) products is possible with TMS(2)MIDA, to afford bench-stable and easily isolable MIDA-boronates in moderate to ...
Gogolin Lars - - 2012
Analysis of multiple protein-protein interactions using microarray technology remains challenging, and site-specific immobilization of functional proteins is a key step in these approaches. Here we establish the efficient synthesis of protein-DNA conjugates for several members of a small family of GTPases. The family of Rab/Ypt GTPases is intimately involved in ...
Lakschevitz Flavia S - - 2012
*Background: Neutrophils, key cells of the innate immune system, were previously thought to be terminally differentiated cells, incapable of altering their gene expression following differentiation and maturation in the bone marrow. Only recently it has been shown that neutrophils carry out rapid and complex changes in gene expression during inflammatory ...
Kang Yoona - - 2012
The ability to adaptively exert control over negative emotions is associated with beneficial mental health outcomes. Less is known about the associated emotional sequelae surrounding controllable versus uncontrollable positive emotional experiences. The ability to harness positive emotions is of particular importance in populations involving disrupted positive emotion functioning. In the ...
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