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Results 401 - 450 of 5706
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van de Ven Peter M - - 2012
Studies for assessing non-inferiority or superiority of a new diagnostic or screening test relative to a standard test use a complete matched-pairs design in which results for both tests are obtained for all subjects. We present alternative tests for the situation where results on the standard test are obtained for ...
O'Connell Motherway Mary M Alimentary Pharmabiotic Centre, National University of Ireland, Western Road, Cork, Ireland; Departments of Microbiology, National University of Ireland, Western Road, Cork, - - 2013
Several prebiotics, such as inulin, fructo-oligosaccharides and galacto-oligosaccharides, are widely used commercially in foods and there is convincing evidence, in particular for galacto-oligosaccharides, that prebiotics can modulate the microbiota and promote bifidobacterial growth in the intestinal tract of infants and adults. In this study we describe the identification and functional ...
Lee Jong Bum - - 2012
Metamaterials are artificial substances that are structurally engineered to have properties not typically found in nature. To date, almost all metamaterials have been made from inorganic materials such as silicon and copper, which have unusual electromagnetic or acoustic properties that allow them to be used, for example, as invisible cloaks, ...
Yatabe Midori Sasaki - - 2012
ABSTRACT: BACKGROUND: Urinary Ca2+ excretion increases with dietary NaCl. NaCl-induced calciuria may be associated with hypertension, urinary stone formation and osteoporosis, but its mechanism and long-term effects are not fully understood. This study examined alterations in the expressions of renal Ca2+ transporters, channels and claudins upon salt loading to better ...
Mak Donna B - - 2012
AIM: Adolescence is the final opportunity for a large-scale immunisation programme before adulthood. The Western Australian (WA) school-based vaccination programme provides Year 7 students with free vaccination against hepatitis B virus (HBV); diphtheria, tetanus and pertussis (dTpa); varicella zoster virus (VZV); and human papilloma virus (HPV). We aimed to identify ...
Tudehope David - - 2012
AIM: To describe decisions made for babies who died in the delivery room as a result of clinical practice of non-resuscitation or unsuccessful resuscitation. METHODS: A retrospective study was conducted of neonatal deaths (NNDs) ≥ 400 g and/or ≥20 weeks' gestation born at Mater Mothers' Hospitals 1998-2009 who were not admitted ...
Rush Elaine - - 2012
AIM: School-based interventions to tackle the rise in childhood overweight and obesity remain inconclusive and are often limited in their application to diverse populations. To inform and measure the effect of the implementation of a primary school-based longitudinal randomised controlled nutrition and activity intervention, Project Energize, baseline measures of body ...
Casper Robert F - - 2012
The concept of using aromatase inhibitors in place of clomiphene citrate (CC) for ovulation induction was introduced >10 years ago; a brief history of its development is presented. Its worldwide usage for ovulation induction, including as an adjunct for intrauterine insemination and in vitro fertilization has occurred despite the absence of ...
Sitbon Olivier - - 2012
It is well established that the endothelin, nitric oxide and prostacyclin pathways play an important role in the development of pulmonary arterial hypertension (PAH). Indeed, the therapeutic options currently available for the management of PAH all act on one of these mechanistic pathways. However, this is an exciting time for ...
Serebryannikov Andriy E - - 2012
Wideband suppression of zero order and relevant strongly asymmetric transmission can be obtained in photonic crystal gratings that are made of linear isotropic materials and show the broken structural (axial) symmetry, even if zero diffraction order may be coupled to a Floquet-Bloch (FB) wave at the incidence and exit interfaces. ...
Hao Jiaming - - 2012
In this Letter, we present a new type of ultrathin antireflection transparent and high-conductive screen based on plasmonic nanostructures that does not suffer from high loss and thickness coating and also can be used as good conductive material due to super electrical conductivity of the component (noble metal). Low reflection ...
Kawahito Tomohisa - - 2012
Tracheo-innominate artery fistula (TIF) is a rare but fatal complication after tracheostomy. Necessary lifesaving measures include proper ventilation, temporary hemostasis, and surgery. Recently, we successfully managed 3 cases of TIF. Ventilation and temporary hemostasis were secured by a long endotracheal tube and overinflated cuff. Division of the innominate artery, restoration ...
Koutras Georgios - - 2012
PURPOSE: Several studies have suggested that drilling the femoral tunnel through an anteromedial arthroscopic portal during anterior cruciate ligament reconstruction allows more anatomic placement of the graft. However, no studies have investigated whether the anteromedial approach results in better outcomes compared to the traditional transtibial drilling approach when a hamstring ...
Birau Amalia - - 2012
Despite advances in treatment, the prognosis for lung cancer patients remains poor. Angiogenesis appears to be a promising target for lung cancer therapy; however, the clinical significance of vascular changes are not completely understood. The aim of this study was to evaluate the types and morphology of blood vessels in ...
Nikolaev Sergey I SI Department of Genetic Medicine and Development, University of Geneva Medical School, 1 rue Michel-Servet, 1211 Geneva, - - 2012
Oncogene-induced DNA replication stress is thought to drive genomic instability in cancer. In particular, replication stress can explain the high prevalence of focal genomic deletions mapping within very large genes in human tumors. However, the origin of single-nucleotide substitutions (SNS) in nonfamilial cancers is strongly debated. Some argue that cancers ...
Cheung Jason Pui-Yin JP Department of Orthopaedics and Traumatology, Queen Mary Hospital, University of Hong Kong, Pokfulam, Hong Kong SAR, - - 2013
Radiotherapy has been the mainstay treatment for nasopharyngeal carcinoma (NPC) and has achieved good disease control. However, irradiation is associated with potential complications such as osteoradionecrosis (ORN) and infection. There is sparse description in the literature of such complications and how they are best managed. The objectives of the study ...
Veeramani Chinnadurai - - 2012
To investigate the protective role of Cardiospermum halicacabum (C. halicacabum) leaf extract on glycoprotein metabolism in streptozotocin (STZ)-induced diabetic rats. Diabetes was induced in male albino Wistar rats by intraperitonial administration of STZ. The C. halicacabum leaf extract (CHE) was administered orally to normal and STZ-diabetic rats for 45 days. ...
Stainsby Brynne E - - 2012
To detail the presentation of two elite female soccer players with right thigh pain that occurred during training. This article will outline the investigation, diagnosis and management of their cases. The patients presented with anterior thigh pain following injuries incurred during training camp. Both were diagnosed with acute muscular strain ...
Zali Aref Rasoulzadeh - - 2012
We propose a photodetector (PD) based on the internal photoemission effect over a Schottky barrier on a CMOS-compatible Si microring resonator for 1.55 μm. To analyze the device, we model the microring waveguide partially covered by a metal/silicide nanolayer, using the Z-transform method. The proposed structure benefits from the resonant-cavity-enhanced (RCE) ...
Kaushal Gur P GP Central Arkansas Veterans Healthcare System, Little Rock, Arkansas 72205, USA. - - 2012
Autophagy is upregulated during ischemia-reperfusion (IR)-induced and cisplatin-induced acute kidney injury (AKI). Proximal tubule-specific Atg7 knockout mice exhibited increased renal injury compared with wild-type mice following cisplatin- and IR-induced AKI. Inhibition of autophagy by chloroquine aggravated AKI, whereas upregulation of autophagy by rapamycin recovered lost renal function and histology, further ...
Takahara Shingo - - 2012
Congenital bicuspid aortic valve (BAV) is one of the most common congenital heart diseases, with a high incidence of associated valvular lesions and aortic abnormalities including aortic stenosis( AS), aortic regurgitation, aortic dilatation, and aortic dissection. Patients with BAV and AS often have a small aortic annulus. We encountered a ...
- - 2012
Council and committee structure Updating the profession's disciplinary machinery These were among matters discussed at the RCVS Council meeting held at Belgravia House in London on November 1. The President, Jacqui Molyneux, was in the chair.
Liu Wei-Dong - - 2012
Fibrosarcoma is a malignant soft tissue tumor of mesenchymal origin. Despite advances in medical and surgical treatment, patient survival rates have remained poor. According to the cancer stem cell hypothesis, tumors are comprised of heterogeneous cell populations that have different roles in tumor formation and growth. Cancer stem cells are ...
Odri Guillaume-A - - 2012
INTRODUCTION: Combining bone marrow (BM) with graft materials can stimulate bone healing. However, bone growth is not quantified in most studies, and the influence of the rate of interconnectivity of ceramics loaded with bone marrow has not yet been quantified. Here, a rabbit model of posterolateral intertransverse arthrodesis was used ...
Sakamaki Kensuke - - 2012
In a previous study, the formation and formation pathway of 6-propylbenzofuran-7-ol as an off-flavor compound formed from ascorbic acid and (E)-hex-2-enal in a test apple beverage was investigated. In the present study, elucidating the pH, temperature, and (E)-hex-2-enal and ascorbic acid concentrations that lead to the generation of 6-propylbenzofuran-7-ol in ...
Mroczek Agnieszka - - 2012
Triterpene saponins in the roots of Beta vulgaris cultivars Red Sphere, Rocket and Wodan were profiled and quantitated using reverse-phase liquid chromatography coupled with electrospray ionization mass spectrometry (HPLC-ESI/MS/MS). Results obtained indicated that the roots of all three cultivars contained 11 saponins consisting of oleanolic acid or hederagenin aglycone and ...
Boyer Andrew C - - 2012
PURPOSE: The purpose of this study was to evaluate the radiographic features of neuroendocrine carcinoma of the urinary bladder (NECB) on CT and to review the literature regarding carcinogenesis, treatment, and prognosis. METHODS: The presenting CT of patients with pathology-proven NECB were retrospectively reviewed for features including size and appearance ...
Morse Stephen S SS Mailman School of Public Health, Columbia University, New York, NY, - - 2012
Most pandemics--eg, HIV/AIDS, severe acute respiratory syndrome, pandemic influenza--originate in animals, are caused by viruses, and are driven to emerge by ecological, behavioural, or socioeconomic changes. Despite their substantial effects on global public health and growing understanding of the process by which they emerge, no pandemic has been predicted before ...
Bagnulo Angela - - 2012
With its increase in participation rate and complex stunts and gymnastic-like maneuvers, cheerleading injuries are on the rise. A structured narrative review of the literature was performed to discover the status of the literature on a growing yet under recognized sport. Cheerleading injuries are described in terms of distribution, etiology, ...
Viana Pedro Couto - - 2012
Rehabilitating anterior edentulous areas can be a challenge for clinicians when there is a loss of hard and soft tissues. The authors present an innovative approach to manage these cases. Case 1 involved a patient with a dental implant placed in the position of tooth no. 7 and a loss ...
Wang Zhen - - 2012
ABSTRACT. Cerebral blood flow (CBF) is critical for the maintenance of cerebral function by guaranteed constant oxygen and glucose supply to brain. Collateral channels (CCs) are recruited to provide alternatives to CBF to ischemic regions once the primary vessel is occluded during ischemic stroke. However, the knowledge of the relationship ...
Okazaki Yoshikazu - - 2012
Coronary aneurysms in adults are rare. The natural history of such coronary aneurysms is unknown. Surgical treatment is often concomitant with the treatment of obstructive coronary lesions. However, the ideal treatment strategy is poorly defined. We herein present a case of successful treatment of a large coronary artery aneurysm with ...
Forbes Jonathan A - - 2012
Object The authors' goal was to better define the relationship between biomechanical parameters of a helmeted collision and the likelihood of concussion. Methods The English-language literature was reviewed in search of scholarly articles describing the rotational and translational accelerations observed during all monitored impact conditions that resulted in concussion at ...
Myers Nicholas D - - 2012
The purpose of this multistudy report was to develop, and then to provide initial validity evidence for measures derived from, the Referee Self-Efficacy Scale. Data were collected from referees (N = 1609) in the United States (n = 978) and Spain (n = 631). In Study 1 (n = 512), ...
Varisli Lokman - - 2012
The family with sequence similarity 83, member D (Fam83D) encodes a mitotic spindle-associated protein. Its knockdown results in shorter spindles that fail to organize a correct metaphase plate. In this study, we demonstrated that Fam83D is coexpressed with well-known mitotic genes. Pathway analysis results also showed that cell cycle- and ...
Zhao Kunpeng - - 2012
The tumor necrosis factor-related apoptosis-inducing ligand (TRAIL/Apo2L) is a novel cytotoxic ligand belonging to the TNF superfamily which is currently being developed as a cancer therapeutic drug. Here, we observed the different functions of recombinant TRAIL protein with a foreign protein label and non-labeled TRAIL. We used a prokaryotic expression ...
Vaitkus Saulius - - 2012
The objective of this study was to perform translation, cross-cultural adaptation, and validation of the SNOT-22 in the Lithuanian language. This is a prospective case-control study. The study was conducted at the University clinic. The sino-nasal outcome test 22 (SNOT-22) was translated into the Lithuanian language; the pilot study involved ...
Tetta Ciro - - 2012
The concept that extracellular vesicles may act as paracrine/endocrine effectors is based on the evidence that they are able to transport bioactive molecules between cells, either within a defined microenvironment or remotely, by entering the biologic fluids. Extracellular vesicles, including exosomes and microvesicles, may deliver lipids and various functional transcripts, ...
Boch Steffen - - 2012
Endozoochory plays a prominent role for the dispersal of seed plants, and dispersal vectors are well known. However, for taxa such as ferns and bryophytes, endozoochory has only been suggested anecdotally but never tested in controlled experiments. We fed fertile leaflets of three ferns and capsules of four bryophyte species ...
Tahmasebi P - - 2012
Resistance in Mycobacterium tuberculosis is caused by mutations in genes encoding drug targets. Investigators have already demonstrated the existence of mutations in codons 88 to 94 in the gyrA gene and also in codons 1400, 1401, and 1483 of rrs gene among extensively and extremely drug resistant tuberculosis (XDR & ...
Laframboise Michelle A - - 2012
To present the diagnostic, clinical features, and management of Kienbock's disease and create awareness of the differential diagnosis of this condition in patients presenting with insidious, progressive dorsal wrist pain. A 23-year old male varsity football player presented with insidious progressive dorsal sided wrist pain with reduced wrist flexion and ...
Eldeeb Hany - - 2012
The most commonly used treatments for maliganat dysphagia are stenting and radiotherapy (RT). A prospective data of 91 patients with locally advanced or metastatic esophageal cancer who has been treated with either palliative RT, stent or both. Group I had RT only, Group II had stent only and group III ...
Yamamoto Jun - - 2012
We experienced a rare case of a 76-year-old man with an anterior mediastinal tumor diagnosed postoperatively as atypical thymic carcinoid with hypercalcemia. He was found to have a growing abnormal mediastinal shadow, and admitted. Chest computed tomography scan on admission revealed an anterior mediastinal mass of 4.0 cm in diameter. ...
Siti Shafiyyah C O - - 2012
A survey was undertaken to investigate the prevalence of intestinal and blood parasites among wild rats in urban area of Kuala Lumpur, Malaysia. A total of 137 stool and blood samples were collected from wild rats from Sentul and Chow Kit areas. Five species of rats were captured and supplied ...
Procopio Giuseppe - - 2012
The molecular-targeted agent sorafenib is the first anticancer agent able to slow the progression of advanced/metastatic renal cell carcinoma, a tumor that was formerly refractory to conventional therapy. Experience from everyday clinical practice and investigations exploring the suitability of this agent for patients with harmful pathological conditions has extended the ...
Jeong Hyo-Soon - - 2012
A few types of ceramide are reported to decrease melanin synthesis. In the present study, we examined the effects of an artificial ceramide analog, PC102, on melanogenesis using a spontaneously immortalized melanocyte cell line (Mel-Ab). PC102 is currently used as a moisturizing additive in a variety of cosmetics. Our data ...
Carlucci Annalisa - - 2012
The presence of acute or chronic respiratory failure is often seen as a terminal phase of chronic obstructive pulmonary disease. A great variability in end-of-life practice is observed in these patients mainly because physicians are not always able to correctly predict survival. There is a need for a clear discussion ...
Mott Timothy F - - 2012
Although a universally accepted definition is lacking, mild traumatic brain injury and concussion are classified by transient loss of consciousness, amnesia, altered mental status, a Glasgow Coma Score of 13 to 15, and focal neurologic deficits following an acute closed head injury. Most patients recover quickly, with a predictable clinical ...
Porr Jason - - 2012
To present a case of traumatic hyoid bone fracture and a review of the literature Traumatic hyoid bone fractures are rare, however with the increasing popularity of martial arts the incidence of traumatic hyoid bone fracture may increase in prevalence. A thirteen year old taekwondo athlete collapsed after receiving a ...
Htein Lin - - 2012
We have developed a cost-effective, high-capacity Er-doped fiber amplifier based on the high-power white LED and a large-core Er-doped fiber. Er ions of the fiber with absorption bands at 453, 488, 523, and 654 nm were simultaneously excited by LED pumping and amplification with optical gain over 12 dB at 1550 nm was ...
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