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Lin Tzu-Yin TY Division of Hematology & Oncology, Department of Internal Medicine, School of Medicine, University of California-Davis, Sacramento, CA 95817, - - 2013
This work aimed to determine if the treatment outcomes of bladder cancer could be improved by targeting micelles that are decorated with bladder cancer-specific ligands on the surface and loaded with the chemotherapeutic drug paclitaxel. Targeting efficacy and specificity was determined with cell lines. An in vivo targeting and anti-tumor ...
Nithianantharajah Jess J Genes to Cognition Programme, Centre for Clinical Brain Sciences and Centre for Neuroregeneration, The University of Edinburgh, Edinburgh, - - 2013
The origins and evolution of higher cognitive functions, including complex forms of learning, attention and executive functions, are unknown. A potential mechanism driving the evolution of vertebrate cognition early in the vertebrate lineage (550 million years ago) was genome duplication and subsequent diversification of postsynaptic genes. Here we report, to ...
Hardy Kristina K KK Center for Neuroscience and Behavioral Medicine, Neuropsychology Division, Children's National Medical Center, Washington, DC 20010, USA. - - 2013
Survivors of pediatric brain tumors and acute lymphoblastic leukemia (ALL) are at increased risk for neurocognitive deficits, but few empirically supported treatment options exist. We examined the feasibility and preliminary efficacy of a home-based, computerized working memory training program, CogmedRM, with survivors of childhood cancer. Survivors of brain tumors or ...
Klengel Torsten T Max Planck Institute of Psychiatry, Munich, Germany. - - 2013
Although the fact that genetic predisposition and environmental exposures interact to shape development and function of the human brain and, ultimately, the risk of psychiatric disorders has drawn wide interest, the corresponding molecular mechanisms have not yet been elucidated. We found that a functional polymorphism altering chromatin interaction between the ...
Micó Vicente - - 2012
Common-path phase-shifting lensless holographic microscopy has been recently proposed as a novel approach capable of high numerical aperture imaging in a lensless digital inline holographic microscopy layout [Opt. Lett.35, 3919 (2010)]. Here we present proof-of-concept validation for improving the resolution limit imposed by diffraction in such a setup. This is ...
de la Osa R Alcaraz - - 2012
The optical properties of metallic nanoparticles (NPs) can be described with analytical models based on fundamental quantum mechanical principles, of which the Drude model constitutes the classical limit. Here, we examine the plasmonic properties of silver and gold nanospheres and dimers, with radii ranging from 10 to 1 nm, extending from ...
Dashnaw Matthew L - - 2012
There has been a growing interest in the diagnosis and management of mild traumatic brain injury (TBI), or concussion. Repetitive concussion and subconcussion have been linked to a spectrum of neurological sequelae, including postconcussion syndrome, chronic traumatic encephalopathy, mild cognitive impairment, and dementia pugilistica. A more common risk than chronic ...
Ethan Danna - - 2012
With the rising rates of diabetes and obesity in New York City's poorest communities, efforts to assist low-income residents in spending money to promote nutritious food consumption have increased. The objective of this study was to assess the extent to which Bronx-based grocery stores offered nutritious foods on sale through ...
Suzuki Hiromichi - - 2012
Panipenem/betamipron (PAPM/BP) may be highly effective for life-threatening Streptococcus pneumoniae infection. However, the efficacy of PAPM/BP for S. pneumoniae infections has not been compared with that of other antimicrobial agents. We retrospectively compared PAPM/BP with other carbapenems for treatment of life-threatening infections in newly hospitalized adults with pneumococcal bacteremia. Clinical ...
Gaudin Amélie C M - - 2012
Numerous transgenes have been reported to increase rice drought resistance, mostly in small-scale experiments under vegetative-stage drought stress, but few studies have included grain yield or field evaluations. Different definitions of drought resistance are currently in use for field-based and laboratory evaluations of transgenics, the former emphasizing plant responses that ...
Yoshimachi Fuminobu - - 2012
A 72-year-old male with effort angina pectoris and old myocardial infarction underwent percutaneous coronary intervention (PCI). A 4 Fr sheath was inserted in the radial artery. After diagnostic angiography, a guidewire was inserted from the diagnostic catheter. The diagnostic catheter is removed, and the distal tip of the guidewire remains in ...
Wood Stephen P - - 2012
Contrast-induced nephropathy is an iatrogenic disease caused by the administration of iodinated contrast material to certain at-risk patients. The clinical features include renal failure, with oliguria, anuria, and electrolyte derangements. Contrast-induced nephropathy can prolong hospitalization, result in greater morbidity and mortality, and increase patients' costs. A variety of preventive and ...
Xu Wei - - 2012
Excited by a 980 nm laser, upconversion emissions centered at 384 (Er<sup>3+</sup>:G4<sub>11/2</sub>→I4<sub>15/2</sub>) and 408 nm (Er<sup>3+</sup>:H2<sub>9/2</sub>→I4<sub>15/2</sub>) in Er<sup>3+</sup>/Yb<sup>3+</sup> codoped polycrystalline CaWO<sub>4</sub> were successfully obtained. The G<sub>11/2</sub>4 and H<sub>9/2</sub>2 states of Er<sup>3+</sup> were verified to be thermally coupled levels, which can emit the shortest wavelength emissions for optical thermometry known so far. Based ...
Eyo J E - - 2012
Urinary schistosomiasis is caused by the deposition of eggs by adult flukes in the blood vessels surrounding the bladder of the infected host. Schistosomiasis is ranked the second most important parasitic disease of man and undoubtedly the most important of helminth origin. This paper reports the prevalence of Schistosoma haematobium ...
Liu Tingting - - 2012
HSP40, also known as DnaJ, is one of the subfamilies of the heat shock protein family. DnaJ/Hsp40 proteins act as co-chaperones by binding to the chaperone Hsp70 through their J domain and stimulating ATP hydrolysis to aid protein translation, folding, unfolding, translocation and degradation. They are implicated in various human ...
Dalsgaard Søren - - 2012
The proposed revision of the diagnostic criteria in DSM-5 for attention-deficit/hyperactivity disorder (ADHD) will not fundamentally change the concept of ADHD. This is mainly due to the fact that, DSM-5 will retain the exact DSM-IV wording of all 18 symptoms, but will add new examples that make the criteria more ...
Halder Dipti - - 2012
This study investigates the risk of arsenic (As) exposure to the communities in rural Bengal, even when they have been supplied with As safe drinking water. The estimates of exposure via dietary and drinking water routes show that when people are consuming water with As concentration <10 µg L-1, the ...
Sugawara Nobuo - - 2012
We report a successful second delivery of a healthy infant fathered using refrozen thawed testicular sperm from an infertile male chimera. We also examined sex chromosome distribution of the seminiferous tubule. Intracytoplasmic sperm injection (ICSI) was performed using the remaining refrozen testicular sperm, which had been stored during the first ...
Linke Diana - - 2012
Investigating the secretion of esterases by the basidiomycetous fungus Pleurotus sapidus in a Tween 80-rich nutrient medium, an enzyme was discovered that hydrolyzed the ester bond of feruloylated saccharides. The enzyme was purified by ion exchange and size exclusion chromatography. Polyacrylamide gel electrophoresis analysis showed a monomeric protein of about ...
Klimek L - - 2012
Anaphylaxis is an extreme form of allergic reaction that can be life-threatening. Early treatment of circulatory and pulmonary disturbances is decisive for prognosis. Initial management of anaphylaxis comprises, where possible, interrupting allergen exposure; ensuring a stable airway; summoning emergency services; placing the patient in a safe position, obtaining venous access ...
Guo Jun-Li - - 2012
To construct rapidly a full-length cDNA library from nanogram amounts total RNA of Giardia lamblia (G. lamblia) trophozoites stocked in RNA stabilization reagent. Total RNA of Giardia was extracted using Trizol reagent. A full-length cDNA library of G. lamblia trophozoites was constructed by a long-distance PCR (LD-PCR) method. The recombinant ...
Yang Wei - - 2012
To observe the expression of angiotensin converting enzyme (ACE), angiotensin II (Ang II), cardiac troponin (cTn I), creatine kinase isozymes (CK-MB) and muscle red protein(Myo) after cardiopulmonary bypass (CPB), and to investigate the association of polymorphisms in angiotensin converting enzyme genes and myocardial injury. Sixty-three patients suffered from rheumatic mitral ...
Zhang Y - - 2012
This Letter presents a plasmonic nanostructure consisting of a nanodisk and a nanoring. The nanodisk is outside of the nanoring. The quadrupolar, hexapolar, and octupolar resonance modes of the nanoring are excited easily by the bright dipolar mode of nanodisks. This nanostructure shows strong interaction and deep Fano dips. In ...
Egan Patrick - - 2012
A new laser-based thermostat sensitive to 0.2 mK at room temperature is reported. The method utilizes a fluid-filled prism and interferometric weak-value amplification to sense nanoradian deviations of a laser beam: due to the high thermo-optic coefficient of the fluid (colorless fluorocarbon), the deviation angle through the prism is sensitive to ...
Azira N M S - - 2012
Trichuris dysentery syndrome is caused by Trichuris trichiura which contributes to one of the most common helminthic infections in the world. It is associated with heavy colonic infection that manifests as mucoid diarrhoea, rectal bleeding, rectal prolapse, iron deficiency anaemia, and finger clubbing. Here, we report a case of trichuris ...
Zhang Haiyan - - 2012
The current study sought to assess the role of paraaortic lymphadenectomy (LNE) in females with endometrial cancer. A retrospective analysis of patients diagnosed with endometrial cancer of stage IA to II preoperatively, between 2009 and 2011 was conducted. Patients were included who had suffered from endometrial cancer without preoperative adjuvant ...
Ma Ruimin - - 2012
Low-grade glioma is predisposed to progress to anaplastic astrocytoma and eventually secondary glioblastoma. The malignant transformation may involve the accumulation of multiple genetic alterations. The purpose of this study was to explore the role of miR-544 in glioma progression and discuss whether it may be a novel biomarker of malignant ...
Li Fang - - 2012
Retroviruses encoding the TNF-related apoptosis-inducing ligand (TRAIL) gene were generated by transient transfection of the retrovirus packing cell line BOSC 23 using TRAIL-encoding plasmid. The retrovirus was able to transduce drug-resistant A2780/DDP ovarian carcinoma cells in vitro and induce TRAIL expression in the cells, as detected by western blot assay. ...
Ishida Mitsuaki - - 2012
Clear cell neuroendocrine tumor (NET) is a rare but distinct histopathological variant of NET most often observed in patients with von Hippel-Lindau disease (VHL). Clear cell NET in non-VHL patients is extremely rare and this report is only the second to describe a case of clear cell NET G1 (carcinoid ...
Takahashi Jun - - 2012
BACKGROUND: Quality of life (QOL) is a concern for patients with lumbar spinal stenosis (LSS). In this study, QOL was examined using the 5-item EuroQol (EQ-5D). METHODS: QOL and activities of daily living (ADL) were surveyed for 91 patients who visited 18 medical institutions in our prefecture and were diagnosed ...
Larsen Elisabeth - - 2012
We examined whether use of snus influenced cognitions in terms of smoking expectancies and smoking prototype perceptions in a direction that could promote smoking initiation, thus highlighting potential causal mechanisms between the use of snus and smoking behavior. A telephone-based longitudinal survey among Norwegian adolescents was conducted with two points ...
Makhija Sonia K - - 2012
BACKGROUND: Questionable occlusal caries (QOC) can be defined as clinically suspected caries with no cavitation or radiographic evidence of occlusal caries. To the authors' knowledge, no one has quantified the prevalence of QOC, so this quantification was the authors' objective in conducting this study METHODS: A total of 82 dentist ...
Plainis Sotiris - - 2012
PURPOSE: To evaluate the effects of the wearer's pupil size and spherical aberration on visual performance with centre-near, aspheric multifocal contact lenses (MFCLs). The advantage of binocular over monocular vision was also investigated. METHODS: Twelve young volunteers, with an average age of 27 ± 5 years, participated in the study. LogMAR Visual Acuity ...
Carlucci Annalisa - - 2012
The presence of acute or chronic respiratory failure is often seen as a terminal phase of chronic obstructive pulmonary disease. A great variability in end-of-life practice is observed in these patients mainly because physicians are not always able to correctly predict survival. There is a need for a clear discussion ...
Mott Timothy F - - 2012
Although a universally accepted definition is lacking, mild traumatic brain injury and concussion are classified by transient loss of consciousness, amnesia, altered mental status, a Glasgow Coma Score of 13 to 15, and focal neurologic deficits following an acute closed head injury. Most patients recover quickly, with a predictable clinical ...
Htein Lin - - 2012
We have developed a cost-effective, high-capacity Er-doped fiber amplifier based on the high-power white LED and a large-core Er-doped fiber. Er ions of the fiber with absorption bands at 453, 488, 523, and 654 nm were simultaneously excited by LED pumping and amplification with optical gain over 12 dB at 1550 nm was ...
Someya Satoshi - - 2012
A combined velocity and temperature measurement method using a high-speed camera, a pulsed UV laser, and temperature-sensitive phosphor particles is proposed. The temperature was calculated from the phosphorescence lifetime, while the velocity was obtained from images of the phosphor particles during a single decay. This method was applied to in-cylinder ...
Tan Li - - 2012
Abstract The aim of this systematic review is to assess the effectiveness and safety of Chinese herbal medicine (CHM) in treatment of anovulation and infertility in women. Eight (8) databases were extensively retrieved. The Chinese electronic databases included VIP Information, CMCC, and CNKI. The English electronic databases included AMED, CINAHL, ...
Tormenti Matthew - - 2012
Object Heightened recognition of the prevalence and significance of head injury in sports and in combat veterans has brought increased attention to the physiological and behavioral consequences of concussion. Current clinical practice is in part dependent on patient self-report as the basis for medical decisions and treatment. Magnetoencephalography (MEG) shows ...
Marshall Cassondra - - 2012
Participation in the Special Supplemental Nutrition Program for Women, Infants, and Children (WIC) has been associated with lower rates of breastfeeding; studies have suggested this relationship may be modified by race. The purpose of this study is to examine the association between WIC participation and breastfeeding behaviors among white and ...
Guerra Anna - - 2012
The genetic alterations are responsible for the altered protein expression in tumors. The knowledge of the link between the altered protein expression and genetic alterations may provide potentially important biological and clinical information. In this study, the expression of some protein markers (Gal-3, p21Kip1, CK19) known to be associated to ...
Hong Jingbo - - 2012
The protein amide (1)H(N) chemical shift temperature coefficient can be determined with high accuracy by recording spectra at different temperatures, but the physical mechanism responsible for this temperature dependence is not well understood. In this work, we find that this coefficient strongly correlates with the temperature coefficient of the through-hydrogen-bond ...
Zaballos P - - 2012
Background  The dermoscopic morphology of apocrine hidrocystomas remains to be elucidated. Objective  To evaluate the morphological findings of apocrine hidrocystomas under dermoscopic observation. Methods  Dermoscopic examination of 22 cases of apocrine hidrocystomas was performed to evaluate specific dermoscopic criteria and patterns. Results  The most frequently occurring dermoscopic features were found ...
Sekiya Michiko - - 2012
The intestinal epithelial cells sit at the interface between a lumen and a lamina propria or lymph nodes such as Peyer's patches, where they play important roles in maintaining intestinal homeostasis through chemokine secretion. This study investigated the effect of Hochuekkito (TJ-41)-a traditional Japanese herbal (Kampo) formula used as a ...
Freemantle N - - 2012
AIM: To compare the effect of insulin degludec and insulin glargine on health-related quality of life in patients with Type 2 diabetes starting on insulin therapy. METHODS: Patient-level data from three open-label, randomized, treat-to-target trials of 26 or 52 weeks' duration were pooled using a weighted analysis in conjunction with a fixed-effects ...
Vachiéry Jean-Luc - - 2012
Advances in the diagnosis and management of pulmonary arterial hypertension (PAH) have resulted in significant improvements in outcomes for patients with this devastating and progressive disease. However, because of the non-specific nature of its symptoms, and the low level of suspicion among clinicians, prompt and accurate diagnosis of PAH as ...
Zorzos Anthony N - - 2012
To deliver light to the brain for neuroscientific and neuroengineering applications like optogenetics, in which light is used to activate or silence neurons expressing specific photosensitive proteins, optical fibers are commonly used. However, an optical fiber is limited to delivering light to a single target within the 3D structure of ...
Miller John - - 2012
We present the first demonstration of real-time closed-loop control and deterministic tuning of an independently suspended Fabry-Perot optical cavity using digitally enhanced heterodyne interferometry, realizing a peak sensitivity of ∼10  pm/Hz over the 10-1000 Hz frequency band. The methods presented are readily extensible to multiple coupled cavities. As such, we anticipate that ...
Zhou Jianwei - - 2012
The aim of this study was to examine the correlation between cofilin 1 expression and differentiation of epithelial ovarian cancer in patients. We immunohistochemically analyzed 30 patients with primary ovarian epithelial carcinomas, 14 patients with borderline epithelial ovarian tumors, 13 patients with benign epithelial ovarian tumors and 10 normal ovarian ...
Solari Nicoletta - - 2012
OBJECTIVE: To evaluate the rate of inactive disease in children with juvenile idiopathic arthritis (JIA) treated with etanercept, and to identify clinical characteristics associated with attainment of inactive disease. METHODS: Clinical charts of patients who were given etanercept between January 2002 and January 2011 were evaluated retrospectively. For each patient, ...
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