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Results 201 - 250 of 5706
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Suresh Anil K - - 2012
Metal and metal oxide nanoparticles are among the most commonly used nanomaterials and their potential for adversely affecting environmental systems raises concern. Complex microbial consortia underlie environmental processes, and the potential toxicity of nanoparticles to microbial systems, and the consequent impacts on trophic balances, is particularly worrisome. The diverse array ...
Jensen DE López Kristine - - 2012
ABSTRACT This study examines the comprehension and production of subject and object relative clauses (SRCs, ORCs) by children with Specific Language Impairment (SLI) and their typically developing (TD) peers. The purpose is to investigate whether relative clauses are problematic for Danish children with SLI and to compare errors with those ...
Li Yifei - - 2012
OBJECTIVE: Percutaneous transcatheter occlusion has benefited thousands of patients suffering from patent foramen ovale and atrial septal defect. However, no general agreement has been reached on the superiority among occluders. Thus, a meta-analysis between the two most commonly adopted types of occluders was conducted. METHODS: The literature review has identified ...
Chen Hui H Department of Cardiology, Zhongnan Hospital of Wuhan University, - - 2013
To study the effects of Na(+) channel blocker flecainide and L-type Ca(2+) channel antagonist verapamil on the voltage-gated fKv1.4ΔN channel, an N-terminal-deleted mutant of the ferret Kv1.4 K(+) channel. fKv1.4ΔN channels were stably expressed in Xenopus oocytes. The K(+) currents were recorded using a two-electrode voltage-clamp technique. The drugs were ...
Mayhew Les - - 2012
There is increasing concern about the lack of accuracy in population projections at national levels. A common problem has been the systematic underestimation of improvements in mortality, especially at older ages, resulting in projections that are too low. In this paper, we present a method that is based on projecting ...
Stadelmann Mathieu - - 2012
Although heart donation after cardiac death (DCD) could greatly improve graft availability, concerns regarding warm ischemic damage typically preclude transplantation. Improving tolerance to warm ischemia may thus open a window of opportunity for DCD hearts. We investigated the hypothesis that, compared with normothermia, mild hypothermia (32° C) initiated after ischemic onset ...
Lin Lin - - 2012
Shell@core-nanostructured TiO(2)@ZnO n-p-n heterojunction nanorods with diameter of 30 nm were successfully fabricated via a hydrothermal method. The photodegradation rate of the TiO(2)@ZnO n-p-n nanorods evaluated by photodegrading methyl orange has been demonstrated to increase three times compared to that of wurtzite hexagonal ZnO. Anatase TiO(2) and Ti(2)O(3) grow along ...
Lampard Amy M - - 2012
OBJECTIVE: To determine if the relationships between additional maintaining factors and core eating disorder maintaining mechanisms outlined in the cognitive-behavioural model of eating disorders are transdiagnostic. METHOD: Patients (n = 1451) diagnosed with anorexia nervosa, bulimia nervosa (BN) or eating disorder not otherwise specified completed the Eating Disorder Examination Questionnaire, Eating Disorder ...
Mabbott Samuel - - 2012
A new optimisation strategy for the SERS detection of mephedrone using a portable Raman system has been developed. A fractional factorial design was employed and the number of statistically significant experiments (288) was greatly reduced from the actual total number of experiments (1722), which minimised the workload whilst maintaining the ...
Rusten Espen - - 2012
Purpose. To study soft tissue sarcomas using dynamic positron emission tomography (PET) with the glucose analog tracer [(18)F]fluoro-2-deoxy-D-glucose ((18)FDG), to investigate correlations between derived PET image parameters and clinical characteristics, and to discuss implications of dynamic PET acquisition (D-PET). Material and methods. D-PET images of 11 patients with soft tissue ...
Mames Iwona - - 2012
A new type of hetero- and homo-polynuclear complexes of copper(ii) and nickel(ii) containing 1,2,3-triazole groups in polymethylene chains have been synthesized and characterized using NMR and electrochemical methods. The triazole link facilitates the synthesis of hetero-dinuclear macrocyclic complexes. Introducing the triazole unit into the complex structure can lead to increased ...
Proto William R WR Wellcome Trust Centre for Molecular Parasitology, Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, G12 8TA, - - 2013
Apoptosis and other types of regulated cell death have been defined as fundamental processes in plant and animal development, but the occurrence of, and possible roles for, regulated cell death in parasitic protozoa remain controversial. A key problem has been the difficulty in reconciling the presence of apparent morphological markers ...
Boivin Michel - - 2012
The Quebec Newborn Twin Study (QNTS) is an ongoing prospective longitudinal follow-up of a birth cohort of twins born between 1995 and 1998 in the greater Montreal area, Québec, Canada. The goal of QNTS is to document individual differences in the cognitive, behavioral, and social-emotional aspects of developmental health across ...
Chan George C - - 2012
A statistical protocol was developed and verified for automated signaling of matrix interferences in inductively coupled plasma-atomic emission spectrometry (ICP-AES). Spatial emission profiles in ICP-AES are versatile indicators for flagging matrix interference. A family of calibration curves is first generated by measurements of standard solutions at different spatial locations in ...
Nicolaou K C - - 2012
At the core of chemistry lie the structure of the molecule, the art of its synthesis, and the design of function within it. This Essay traces the understanding of the structure of the molecule, the emergence of organic synthesis, and the art of total synthesis from the 19th century to ...
Jardim Denis Leonardo Fontes - - 2012
Objectives: Bevacizumab has been approved by the US Food and Drug Administration as a first-line therapy for metastatic non-small-cell lung cancer (NSCLC), in combination with carboplatin and paclitaxel. A single Latin American center experience was reviewed to determine the safety and efficacy of adding bevacizumab to first-line chemotherapy in a ...
Wilson Robert L - - 2012
The uneven cholesterol distribution among organelles and within the plasma membrane is postulated to be critical for proper cellular function. To study how interactions between cholesterol and specific lipid species contribute to the uneven cholesterol distribution between and within cellular membranes, model lipid membranes are frequently employed. Although the cholesterol ...
Wang Wei - - 2012
Conventionally, rechargeable batteries with a fast charge-discharge rate, while being able to be implemented in large-scale applications with low prices, are critical for new energy storage systems. In this work, first-principles simulations were employed to theoretically investigate the insertion of sodium into the Na(2)Ti(3)O(7) structure. The result discovered that the ...
Peng Qiuming - - 2012
The objective of this study was to prepare a new biodegradable Mg-based biomaterial, which provides good mechanical integrity in combination with anti-inflammatory function during the degradation process. The silver element was used, because it improved the mechanical properties as an effective grain refiner and it is also treated as a ...
Hodge Allison - - 2012
ABSTRACT Background: Anxiety and depression contribute to morbidity in elderly adults and may be associated with diet. We investigated the association between diet and psychological distress as a marker for depression. Methods: Dietary patterns were defined by factor analysis or the Mediterranean Diet Score (MDS); depression and anxiety were assessed ...
Kroneisen Meike - - 2012
Nairne and collaborators showed that assessing the relevance of words in the context of an imagined survival scenario boosts memory for these words. Although this survival-processing advantage has attracted a considerable amount of research, little is known about the proximate memory mechanism mediating this effect. Recently, Kroneisen and Erdfelder (2011) ...
Albrecht B - - 2012
BACKGROUND: Patients with attention deficit-hyperactivity disorder (ADHD) exhibit difficulties in multiple attentional functions. Although high heritability rates suggest a strong genetic impact, aetiological pathways from genes and environmental factors to the ADHD phenotype are not well understood. Tracking the time course of deviant task processing using event-related electrophysiological brain activity ...
Parés-Casanova P M - - 2012
The purpose of this article was to examine the level of sexual dimorphism exhibited in the foramen magnum and occipital condyles of bovine juveniles and to test the utility of three basicranial measurements for estimating sex and to evaluate breed differences. Data were taken from 68 bovines of known sex, ...
Alibek Kenneth - - 2012
ABSTRACT: Since the late 1990s, infectious agents have been thought to play a role in the pathogenesis of approximately 15% of cancers. It is now widely accepted that infection of stomach tissue with the bacteria Helicobacter pylori is an important cause of stomach adenocarcinoma. In addition, oncogenic viruses, such as ...
Zhang Delong - - 2012
Spectroscopic imaging has been an increasingly critical approach for unveiling specific molecules in biological environments. Towards this goal, we demonstrate hyperspectral stimulated Raman loss (SRL) imaging by intra-pulse spectral scanning through a femtosecond pulse shaper. The hyperspectral stack of SRL images is further analyzed by a multivariate curve resolution (MCR) ...
Cook Kevin T - - 2012
We demonstrate a method for producing thickness- and refractive index-tunable antireflection coatings utilizing a one-step spin coating procedure with commercially available silica nanoparticle solutions. Aging nanoparticle solutions under controlled pH and temperature induces nanoparticle aggregation, which provides a precise way to control the porosity and thus refractive index of the ...
Kim Hun Young - - 2012
The elimination pathway of stereochemically defined β-halovinyl ketones has been investigated using a mild base NEt3, leading to the formation of allenyl ketones and propargyl ketones. A preferential α-vinyl enolization of (E)-β-chlorovinyl ketones has been observed where a non-planar s-cis conformation is proposed as a dominant conformation as opposed to ...
Niu Yi - - 2012
We consider a marginal model for the regression analysis of clustered failure time data with a cure fraction. We propose to use novel generalized estimating equations in an expectation-maximization algorithm to estimate regression parameters in a semiparametric proportional hazards mixture cure model. The dependence among the cure statuses and among ...
Hayashi Takuya - - 2013
A cell-based therapy for the replacement of dopaminergic neurons has been a long-term goal in Parkinson's disease research. Here, we show that autologous engraftment of A9 dopaminergic neuron-like cells induced from mesenchymal stem cells (MSCs) leads to long-term survival of the cells and restoration of motor function in hemiparkinsonian macaques. ...
Rawson Kenneth G - - 2012
AIM: The purpose of this study was to evaluate the concentrations of fluoride in community water at the point of source, compared to the concentration delivered to various locations within the Las Vegas Valley, to determine if the levels of fluoride change over distance. METHODS: Ten samples per week over ...
Mickes Laura - - 2012
We investigated the nature of motor symptoms in the preclinical stage of Huntington's disease. Individuals with the CAG expanded repeat of Huntington's disease (prHD) and two control groups were tested on a task requiring a releasing movement (releasing a depressed button) followed by a ballistic movement (pressing a different button). ...
D'Onofrio Philippe M PM Faculty of medicine, Division of Anatomy, Department of Surgery, University of Toronto, Ontario, - - 2013
Retinal ischemia is a very useful model to study the impact of various cell death pathways, such as apoptosis and necrosis, in the ischemic retina. However, it is important to note that the retina is formed as an outpouching of the diencephalon and is part of the central nervous system. ...
Vignes-Adler Michèle - - 2012
Bubble, bubble: Why does champagne bubble? Why does it stop bubbling? Does the vintage affect its fizz? Chemistry can answer these and other questions about the wine that is so often associated with celebrations and anniversaries.
Mossman Jim A - - 2013
Recent studies investigating possible causes of male subfertility have largely focused on how lifestyle or environmental factors impact on the process of spermatogenesis. Markedly, fewer studies have investigated those risk factors that result in reduced sperm quality, such as poor sperm motility. The speed at which sperm swim is a ...
Tong Steven Y C - - 2012
This month's Genome Watch highlights the advantages of using whole-genome sequencing for infectious-disease surveillance and infection control.
Faber Katrin K Department of Internal Medicine III, Ulm University, Ulm, - - 2013
Aberrant expression of the homeodomain transcription factor CDX2 occurs in most cases of acute myeloid leukemia (AML) and promotes leukemogenesis, making CDX2, in principle, an attractive therapeutic target. Conversely, CDX2 acts as a tumor suppressor in colonic epithelium. The effectors mediating the leukemogenic activity of CDX2 and the mechanism underlying ...
Interian Alejandro - - 2012
OBJECTIVE: Unequal mental health among U.S. underserved racial-ethnic populations has become a prominent national concern. Contributing to this inequity is our limited ability to engage individuals from underserved populations into treatment. To help address this, a systematic literature review was conducted to examine the evidence base for interventions that can ...
Hoffmann Reinhard W - - 2012
For almost 200 years, the synthesis of natural products has been practiced. In this time span, not only the target structures have become increasingly more complex (see two examples from the 1970s), the objectives of natural product synthesis have also changed. Likewise, the standards and criteria for the conduction of ...
Karbalaei Narges - - 2012
Objective. Since thyroid hormones play fundamental roles in somatic growth and metabolism, disturbances of thyroid function affect many organs and systems. Both fetal hypothyroidism and aging can affect carbohydrate metabolism during adult life. This study aims to assess the glucose tolerance and insulin secretion capacity of islets in young and ...
Dang Jun - - 2012
Grade ≥ 3 radiation pneumonitis (RP) is generally severe and life-threatening. Predictors of grade ≥ 2 are usually used for grade ≥ 3 RP prediction, but it is unclear whether these predictors are appropriate. In this study, predictors of grade ≥ 2 and grade ≥ 3 RP were investigated separately. ...
Chang Yu-Ching - - 2012
A simple pretreatment procedure was developed for the analysis of dioxins in soil samples using gas chromatography/multiphoton ionization/time-of-flight mass spectrometry. The sample was subjected to a pressurized liquid extraction procedure, followed by separation using a pair of Sulfoxide and Ag-ION columns for clean-up. Due to the high selectivity of laser ...
Lanteri G - - 2012
Male cross-breed lamb conjoined twins were sent for examination. The twins came from a farm located in the outskirts of Palermo. The twins were spontaneously delivered and found dead by the farmer. X-ray examination and necropsy were performed. The deformity was identified as deradelphus cephalo-thoracoomphalopagus. This condition has never been ...
Li Jing J Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, - - 2013
To investigate the molecular mechanisms underlying the influence of DNA polymerase from different genotypes of hepatitis B virus (HBV) on the binding affinity of adefovir (ADV). Computational approaches, including homology modeling, docking, MD simulation and MM/PBSA free energy analyses were used. Sequence analyses revealed that residue 238 near the binding ...
Hopper John L - - 2012
The Australian Twin Registry (ATR) is a national volunteer resource of twin pairs and higher-order multiples willing to consider participating in health, medical, and scientific research. The vision of the ATR is 'to realize the full potential of research involving twins to improve the health and well-being of all Australians'. ...
Berlim M T - - 2012
BACKGROUND: Bilateral repetitive magnetic stimulation (rTMS) is a promising novel therapeutic intervention for major depression (MD). However, clinical trials to date have reported conflicting evidence concerning its overall efficacy, which might have resulted from low statistical power. Thus, meta-analytical approaches could be useful in examining this issue by allowing the ...
Zheng Mingming - - 2012
In this study, a novel mixed-mode composite material SiO2@P(MAA-co-VBC-co-DVB) was prepared via the hypercrosslinking of its precursor which was produced via suspension polymerization in the presence of SiO2 particles. Candida rugosa lipase (CRL) was immobilized on the SiO2@P(MAA-co-VBC-co-DVB) particles via hydrophobic and weak cation-exchange interaction. The resulting immobilized CRL showed ...
Juniper D T - - 2012
The objective of this study was to determine the concentration of total selenium (Se) and the proportions of total Se comprised as selenomethionine (SeMet) and selenocysteine (SeCys) in the postmortem tissues of female pheasants (Phasianus Colchicus Torquator) offered diets that contained graded additions of selenised-enriched yeast (SY) or a single ...
Tang Heqing - - 2012
Direct evidences were first demonstrated for the oxidative degradation of decabromodiphenyl ether (BDE209) in aqueous TiO2 dispersions under UV irradiation (λ>340 nm). BDE209 was hardly debrominated over TiO2 in UV-irradiated acetonitrile dispersions, but the addition of water into the dispersions greatly enhanced its photocatalytic oxidative debromination. The debromination efficiency of ...
Nastase Anthony F - - 2012
Beta-site amyloid precursor protein cleaving enzyme-1 (BACE1) is a target of interest for treating patients with Alzheimer's disease (AD). Inhibition of BACE1 may prevent amyloid-ß (Aß) plaque formation and the development or progression of Alzheimer's disease. Known BACE1 inhibitors were analyzed using computational chemistry and cheminformatics techniques to search for ...
Lebkowska-Wieruszewska B - - 2012
The residue depletion profile of sulfachlorpyrazine was studied in healthy broilers after oral administration of Sulfatyf®, given at a dose of 50 mg sulfachlorpyrazine (SCP) per kg body weight once daily for 3 consecutive days. Twenty-five medicated broilers were slaughtered on the 5th, 10th, 14th and 16th day of post-medication, and ...
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