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Saroul Nicolas - - 2013
Investigation of long-term satisfaction and correlation with audiometric measurements after osseointegrated bone-conduction device (OBCD) surgery for patients with single-sided deafness (SSD). Thirty-six patients implanted with an OBCD for SSD. Retrospective review in a university medical center. Rehabilitative. The patients were implanted after a test with an OBCD worn on a ...
Synnøve Moan Inger - - 2013
ABSTRACT. Objective: The aim of this study was twofold: (a) to examine how an increase in the frequency of heavy drinking episodes affects the incidence of drunk driving and (b) to examine whether the effect of alcohol use on drunk driving is contingent on impulsivity.Method: Two waves of the Young ...
Swallow K K Immunology Department and Protein Reference Unit, Northern General Hospital, Sheffield, - - 2013
National Institute of Clinical Excellence (NICE) and European Society for Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN) guidance for the diagnosis of coeliac disease has been published. However, there is some controversy regarding the advice on the use of stratifying levels of immunoglobulin (IgA) tissue transglutaminase antibody (TG2) test positivity in ...
Espinosa Geovanni - - 2013
Nutrition seems to modify the pathogenesis of benign prostatic hyperplasia (BPH) effect symptomology in men suffering from lower urinary tract symptoms (LUTS). Although there are numerous pharmaceuticals and procedures for these conditions, nutrition may improve outcomes as a primary approach or in tandem with BPH medications or procedures. The purpose ...
Whiteside Lauren K LK Division of Emergency Medicine, University of Washington, Seattle, WA 98104, USA. - - 2013
The purpose of this study was to identify overlap and violence types between peer and dating aggression and victimization using latent class analysis (LCA) among a sample of aggressive adolescents with a history of alcohol use and to identify risk and protective factors associated with each violence class. From September ...
Smith Patrick P Department of Psychology, King's College London, Institute of Psychiatry, London, UK. - - 2013
We review recent evidence regarding risk factors for childhood posttraumatic stress disorder (PTSD) and treatment outcome studies from 2010 to 2012 including dissemination studies, early intervention studies and studies involving preschool children. Recent large-scale epidemiological surveys confirm that PTSD occurs in a minority of children and young people exposed to ...
Selzler Katherine - - 2013
Subthalamic nucleus (STN) deep brain stimulation (DBS) has become an accepted treatment for the motor manifestations of Parkinson disease (PD). The beneficial motor effects of STN DBS are likely due to modulation of BG output to frontal cortical regions associated with motor control, but the underlying neurophysiology of STN DBS ...
McHugh R Kathryn RK Division of Alcohol and Drug Abuse, McLean Hospital, Belmont, MA 02478, USA. - - 2013
Reactivity to stress is a common feature of alcohol dependence and is associated with poorer treatment outcome among alcohol-dependent patients. Despite the importance of stress reactivity in alcohol dependence, little is known about markers of resilience to stress in this population. The current study examined whether positive affect buffered the ...
Zonneveld-Huijssoon E E Department of Pediatric Immunology, Centre for Cellular and Molecular Intervention, University Medical Centre Utrecht, Utrecht, the - - 2013
Mucosal administration of an antigen eliciting bystander suppression at the site of inflammation results in effective antigen-specific immunotherapy for autoimmune diseases. Heat shock proteins are bystander antigens that are effective in peptide-specific immunotherapy in both experimental and human autoimmune disease. The efficacy of preventive peptide immunotherapy is increased by enhancing ...
Poch Michael A - - 2013
To summarize the fundamental principles for technique of robot-assisted radical cystectomy (RARC) based on current peer reviewed literature. Also provide most recent evidence for the efficacy of RARC and Intracorporeal Ileal Conduit (ICIC). Technical tricks have increased the efficiency of RARC and ICIC diversion. Perioperative and short-term outcomes have demonstrated ...
Turrisi Rob R Prevention Research Center, The Pennsylvania State University, University Park, PA 16802, USA. - - 2013
The study evaluated the timing and dosage of a parent-based intervention to minimize alcohol consumption for students with varying drinking histories. First-year students (N = 1,900) completed Web assessments during the summer before college (baseline) and two follow-ups (fall of first and second years). Students were randomized to one of ...
Claus Eric D ED The Mind Research Network and Lovelace Biomedical and Environmental Research Institute, Albuquerque, NM 87106, USA. - - 2013
The current study examined the relationship between severity of alcohol use disorders (AUDs) and the neural circuits that underlie response inhibition and error monitoring. In addition, we explored pre- and post-inhibition trial processes to determine the potential causal mechanisms responsible for disinhibition in AUDs. One hundred sixty-four individuals with a ...
Simoni Y Y INSERM, U986, Hospital Cochin/St Vincent de Paul, Université Paris Descartes, Paris, - - 2013
T cells reactive to lipids and restricted by major histocompatibility complex (MHC) class I-like molecules represent more than 15% of all lymphocytes in human blood. This heterogeneous population of innate cells includes the invariant natural killer T cells (iNK T), type II NK T cells, CD1a,b,c-restricted T cells and mucosal-associated ...
Mair Christina C Prevention Research Center, Pacific Institute for Research and Evaluation, Berkeley, CA 94704, USA. - - 2013
Groups of potentially violent drinkers may frequent areas of communities with large numbers of alcohol outlets, especially bars, leading to greater rates of alcohol-related assaults. This study assessed direct and moderating effects of bar densities on assaults across neighborhoods. We analyzed longitudinal population data relating alcohol outlet densities (total outlet ...
Naylor A J AJ Rheumatology Research Group, Centre for Translational Inflammation Research, School of Immunity and Infection, College of Medical and Dental Sciences, University of Birmingham Research Laboratories, Queen Elizabeth Hospital, Birmingham, - - 2013
Inflammation is an unstable state; it either resolves or persists. Inflammatory reactions often have a propensity for specific anatomical sites. Why inflammation persists with specific tissue tropism remains obscure. Increasing evidence suggests that stromal cells which define tissue architecture are the key cells involved, and therefore make attractive therapeutic targets. ...
Ismail Mohamed Taha - - 2013
Objective: To evaluate the efficacy of 3 progestin treatment regimens in the management of simple endometrial hyperplasia without cytological atypia in premenopausal women. Study Design: Prospective randomized comparative study. The study included 90 premenopausal women with histological diagnosis of simple endometrial hyperplasia (EH) without atypia, during the period from January ...
Mercier Laurence - - 2013
The goal of this study was to find a registration technique to improve the alignment of ultrasound images taken before and after brain tumor resection. Validation was performed on 16 tumor cases in 2 ways: (1) manually selected tags on pre- and postresection ultrasounds were used to compute the mean ...
Zemore Sarah E SE Alcohol Research Group, Emeryville, CA 94608, USA. - - 2013
We examined whether race/ethnicity was related to exposure to acute economic losses in the 2008-2009 recession, even accounting for individual-level and geographic variables, and whether it influenced associations between economic losses and drinking patterns and problems. Data were from the 2010 National Alcohol Survey (N = 5,382). Surveys assessed both ...
Arria Amelia M AM Center on Young Adult Health and Development, University of Maryland School of Public Health, Department of Family Science, College Park, MD 20742, USA. - - 2013
Few longitudinal studies have examined the relationship between illicit drug use and academic outcomes among college students. This study characterized drug use patterns of a cohort of young adults who were originally enrolled as first-time, first-year college students in a longitudinal study. It evaluated the association between these drug use ...
LaRocque Joshua J - - 2013
For decades it has been assumed that sustained, elevated neural activity--the so-called active trace--is the neural correlate of the short-term retention of information. However, a recent fMRI study has suggested that this activity may be more related to attention than to retention. Specifically, a multivariate pattern analysis failed to find ...
Marzano A V AV Unità Operativa di Dermatologia, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Dipartimento di Fisiopatologia Medico-Chirurgica e dei Trapianti, Università degli Studi di Milano, Milano, - - 2013
Bullous pemphigoid (BP) is a potentially life-threatening autoimmune blistering disease that is burdened with an increased risk of cardiovascular events. In BP, there is an interplay between inflammation and coagulation both locally, which contributes to skin damage, and systemically, which leads to a prothrombotic state. Fibrinolysis is an important defence ...
Pontiki Eleni E Department of Pharmaceutical Chemistry, School of Pharmacy, Aristotle University of Thessaloniki, Thessaloniki, Greece. - - 2013
Neuroinflammation and oxidative stress are contributing factors to neurodegeneration in physiological aging as well as in age-related neurological disorders. Neuroinflammation can be both a cause and a result of chronic oxidative stress. The role of the oxidative stress and free radicals in the development of Alzheimer's disease (AD) is currently ...
Dasgupta Doyel - - 2013
We examined the attitude of postmenopausal women toward menopause and aging with respect to sociodemographic variables and postmenopausal years. Four hundred and eighty postmenopausal women representing Bengali-speaking Hindu ethnic group of West Bengal, India were interviewed about their attitude toward menopause and aging. Information on sociodemographic and reproductive characteristics and ...
Barbosa Daniel - - 2013
A novel framework to efficiently deal with three-dimensional (3-D) segmentation of challenging inhomogeneous data in real-time has been recently introduced by the authors. However, the existing framework still relied on manual initialization, which prevented taking full advantage of the computational speed of the method. In the present article, an automatic ...
Lu M-C MC Division of Allergy, Immunology and Rheumatology, Buddhist Dalin Tzu Chi General Hospital, Chia-Yi, - - 2013
Systemic lupus erythematosus (SLE) is a systemic autoimmune disease with abnormal T cell immune responses. We hypothesized that aberrant expression of microRNAs (miRNAs) in T cells may contribute to the pathogenesis of SLE. First, we analysed the expression profiles of 270 human miRNAs in T cells from five SLE patients ...
Cha Yoon-Hee YH Department of Neurology, University of California Los Angeles, Los Angeles, California 90095, - - 2013
Mal de debarquement syndrome (MdDS) is a chronic disorder of imbalance characterized by a feeling of rocking and swaying. The disorder starts after prolonged exposure to passive motion such as from a boat or plane. All medical treatment is palliative and symptoms that persist beyond 6 months show low likelihood ...
Fisher Michael P MP RAND Corporation, Arlington, VA 22202, USA. - - 2013
This study examined substance use (intended and actual), unprotected sex, and HIV disclosure practices (disclosure and questioning) among HIV-positive men who have sex with men (MSM) at two party-oriented vacations, where substance use and sexual risk may be heightened. A random sample of 489 MSM attending one of two party-oriented ...
Lee Hsiu-Hao - - 2013
Primary aldosteronism (PA), an underdiagnosed cause of hypertension, is associated with more significant cardiac remodeling and myocardial fibrosis than is essential hypertension (EH). The aim of this study was to validate myocardial fibrosis and to evaluate factors associated with the degree of myocardial fibrosis in patients with PA. We prospectively ...
Regateiro F S FS Sir William Dunn School of Pathology, University of Oxford, Oxford, - - 2013
Extracellular adenosine 5'-triphosphate (ATP) acts on many immune cells to promote inflammation. Conversely, the ATP metabolite adenosine is mainly an anti-inflammatory molecule. The ecto-enzymes CD39 and CD73 can dephosphorylate extracellular ATP to adenosine, thereby controlling this important pathway of immune modulation. Despite their established roles in the immune system, little ...
Montemurro Beth - - 2013
In American society, the sexually desirable woman is young and thin. Changes associated with aging such as wrinkled skin or weight gain often bring women further from societal ideals of attractiveness. As physical appearance is very much related to desirability, we explore sexual body image and the way that it ...
Prasad Sandip M - - 2013
With increasing adoption of minimally invasive surgical techniques in urologic oncology, the efficacy, safety, and adequacy of lymphadenectomy were reviewed for studies about prostate, bladder, kidney, upper tract urothelial, testicular, and penile cancer published in the past 18 months. In prostate cancer, in which robotic prostatectomy has become the predominant ...
Blonigen Daniel M DM Center for Health Care Evaluation, Veterans Affairs Palo Alto Health Care System, Menlo Park, CA 94025, USA. - - 2013
Prior research on predictors of problem drinking has been limited because of an inability to attribute an unambiguous environmental explanation to observed findings. Using a prospective co-twin control design, we examined the extent to which a history of psychiatric symptoms exerts an environmental influence on problem drinking in midlife that ...
Komiya T T Exploratory Research Laboratories, Tsukuba, Ibaraki, Japan. - - 2013
ONO-4641 is a next-generation sphingosine 1-phosphate (S1P) receptor agonist selective for S1P receptors 1 and 5. The objective of the study was to characterize the immunomodulatory effects of ONO-4641 using preclinical data. ONO-4641 was tested in both in-vitro pharmacological studies as well as in-vivo models of transient or relapsing-remitting experimental ...
Byles Julie - - 2013
This quantitative research study uses survey data of women born between 1946 and 1951 in Australia. It follows earlier work that identified the importance of transitions from work for women of the baby boomer generation. We provide important insights into the lives of women who have partially or fully retired ...
Faber Hubert T HT Department of Otorhinolaryngology, Donders Institute for Brain, Cognition and Behaviour, Radboud University Nijmegen Medical Centre, Nijmegen, The - - 2013
To clinically evaluate the performance of a titanium percutaneous bone-anchored hearing implant (BAHI) using a 3-week healing period. Short-term implant survival, stability changes, and skin reactions are evaluated from the initial implantation to 6 months postimplantation. Thirty patients eligible for a BAHI were included in an open, prospective clinical investigation. ...
Sanchez Alma A Garrison Institute on Aging, Texas Tech University Health Sciences Center, Lubbock, TX 79413, - - 2013
Bidirectional communication between neurons and vascular cells is important to the maintenance of the central nervous system (CNS) milieu. Vascular endothelial growth factor (VEGF), through its ability to affect both vascular and neuronal cells, is likely a key protein in this process. Despite considerable literature documenting a neuroprotective function for ...
Gorus F K FK Diabetes Research Center, Brussels Free University, Brussels, - - 2013
In first-degree relatives of type 1 diabetic patients, we investigated whether diabetes risk assessment solely based on insulinoma antigen 2 (IA-2) and zinc transporter 8 (ZnT8) antibody status (IA-2A, respectively, ZnT8A) is as effective as screening for three or four autoantibodies [antibodies against insulin (IAA), glutamate decarboxylase 65 kDa (GAD) ...
Da Costa Laura A - - 2013
Vitamin E is a lipophilic antioxidant that has been inversely associated with certain chronic diseases; however, the biological processes regulated by this vitamin have not been fully elucidated. The objective of the present study was to examine the association between the most biologically active and abundant form of vitamin E ...
Nadel Lynn - - 2013
We discuss the question of differentiation along the anterior-posterior longitudinal axis of the hippocampus. Data from a recent fMRI study are reanalyzed to determine whether activations in these hippocampal regions are affected by the nature of the information being accessed during a scanning session in which participants thought about episodes ...
McCall Holly - - 2013
Ion mobility spectrometry (IMS) is frequently used to gauge the success of remediation in clandestine methamphetamine laboratory sites due to portability of the instrument. In most cases, remediation involves some form of surface cleaning, followed by assaying using IMS to detect residual contaminants. However, the effectiveness of this cleaning approach ...
Innocenti Iglis - - 2013
A classic finding of the psychology of memory is the "serial position effect." Immediate free recall of a word list is more efficient for items presented early (primacy effect) or late (recency effect), with respect to those in the middle. In an event-related, randomized block design, we interfered with the ...
Wang S S Department of Laboratory Medicine, Affiliated People's Hospital, Jiangsu University School of Medical Science and Laboratory Medicine, Zhenjiang, China. - - 2013
Leptin modulates T cell function and plays an important role in autoimmune diseases. Our study aimed to explore the role of leptin and T helper type 17 (Th17) cells in Hashimoto's thyroiditis patients. Twenty-seven patients with Hashimoto's thyroiditis (HT) and 20 healthy controls were enrolled into the current study. A ...
Prasad B Ram BR Department of Chemistry, University of Southern California, SGM 418, 3620 McClintock Avenue, Los Angeles, California 90089, United - - 2013
The nature and mechanism of phosphate hydrolysis reactions are of great interest in view of the crucial role of these reactions in key biological processes. Although it is becoming clearer that the ultimate way of resolving mechanistic controversies must involve reliable theoretical studies, it is not widely realized that such ...
Yang Jiwon J Department of Pharmacology, College of Pharmacy, Sookmyung Women's University, Seoul, Republic of - - 2013
Oxidative stress after stroke is associated with the inflammatory system activation in the brain. The complement cascade, especially the degradation products of complement component 3, is a key inflammatory mediator of cerebral ischemia. We have shown that pro-inflammatory complement component 3 is increased by oxidative stress after ischemic stroke in ...
Silvers William C WC Department of Chemistry, Louisiana State University, Baton Rouge, Louisiana 70803-1804, United - - 2013
Achieving the vision of identifying and quantifying cancer-related events and targets for future personalized oncology is predicated on the existence of synthetically accessible and economically viable probe molecules fully able to report the presence of these events and targets in a rapid and highly selective and sensitive fashion. Delineated here ...
Orozco-Alcaraz Raquel R Department of Chemical Engineering and Materials Science, University of California-Davis, One Shields Avenue, Davis California 95616, United - - 2013
The surface force apparatus (SFA) was utilized to obtain force-distance profiles between silica-supported membranes formed by Langmuir-Blodgett deposition of 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC). In the absence of a membrane, a long-range electrostatic repulsion and short-range steric repulsion are measured as a result of the deprotonation of silica in water and the roughness ...
Budin Itay - - 2012
The first protocell membranes may have assembled from fatty acids and related single-chain lipids available in the prebiotic environment. Prior to the evolution of complex cellular machinery, spontaneous protocell membrane growth and division had to result from the intrinsic physicochemical properties of these molecules, in the context of specific environmental ...
Pan Jianjun J Neutron Sciences Directorate, Oak Ridge National Laboratory, Oak Ridge, Tennessee 37831, United States. - - 2012
Cholesterol and ether lipids are ubiquitous in mammalian cell membranes, and their interactions are crucial in ether lipid mediated cholesterol trafficking. We report on cholesterol's molecular interactions with ether lipids as determined using a combination of small-angle neutron and X-ray scattering, and all-atom molecular dynamics (MD) simulations. A scattering density ...
Nsimba Robert Y - - 2012
This work deals with antioxidant properties of pyrolytic lignins against two free radicals, 1,1-diphenyl-2-picrylhydrazyl and 2,2'-azinobis(3-ethylbenzothiazoline-6-sulfonic acid). Pyrolytic lignins produced by the thermal pyrolysis of the Etek lignin were extracted from the liquid pyrolysis product and fractionated using solvents of different polarities. The main functional groups linked to the lignin ...
Martines Elena - - 2012
Broadly neutralizing anti-HIV-1 monoclonal antibody 2G12 exclusively targets a conserved cluster of high-mannose oligosaccharides present on outer viral envelope glycoprotein gp120. This characteristic makes the otherwise immunogenically "silent" glycan shield of gp120 a tempting target for drug and vaccine design. However, immune responses against carbohydrate-based mimics of gp120 have failed ...
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