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Results 601 - 650 of 5706
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Miller John - - 2012
We present the first demonstration of real-time closed-loop control and deterministic tuning of an independently suspended Fabry-Perot optical cavity using digitally enhanced heterodyne interferometry, realizing a peak sensitivity of ∼10  pm/Hz over the 10-1000 Hz frequency band. The methods presented are readily extensible to multiple coupled cavities. As such, we anticipate that ...
Zhou Jianwei - - 2012
The aim of this study was to examine the correlation between cofilin 1 expression and differentiation of epithelial ovarian cancer in patients. We immunohistochemically analyzed 30 patients with primary ovarian epithelial carcinomas, 14 patients with borderline epithelial ovarian tumors, 13 patients with benign epithelial ovarian tumors and 10 normal ovarian ...
Solari Nicoletta - - 2012
OBJECTIVE: To evaluate the rate of inactive disease in children with juvenile idiopathic arthritis (JIA) treated with etanercept, and to identify clinical characteristics associated with attainment of inactive disease. METHODS: Clinical charts of patients who were given etanercept between January 2002 and January 2011 were evaluated retrospectively. For each patient, ...
Schiavo-Cardozo Daniela - - 2012
OBJECTIVE: Shift work is associated to circadian rhythm disorder, impaired sleep and behavioral changes, including eating habits, predisposing to obesity and metabolic dysfunctions. It involves a neuro-hormonal dysregulation of appetite towards positive energy balance, including increased ghrelin and decreased leptin, but little is known about other hormones, such as xenin, ...
Cao Lili - - 2012
INTRODUCTION AND HYPOTHESIS: The aim of this study was to compare the effectiveness and long-term anatomic and functional results of laparoscopic peritoneal vaginoplasty and laparoscopic sigmoid vaginoplasty. METHODS: From January 2002 to December 2010, 40 patients with congenital vaginal agenesis were prospectively randomized to undergo either laparoscopic peritoneal vaginoplasty (26 ...
Hardin Sonya R - - 2012
Older adults with hearing loss who receive care in the noisy environment of a critical care unit can be disadvantaged in their ability to understand speech, thus limiting their participation in decision making. Providing optimal outcomes for such patients can be understood through use of the American Association of Critical-Care ...
Eichhorn K W G - - 2012
Otorhinolaryngologists require new diagnostic methods to give further insight into the physiology of nasal breathing. The functional aspects of radiological data in the field of ENT have rarely been examined. This study compares computed tomography (CT) scan area measurements of the paranasal sinuses with physiological data from rhinomanometry. In a ...
Dörenberg Vivianne - - 2012
Two vulnerable groups in our society are children with psychiatric problems and people with intellectual disabilities. The demand for care is growing every year in both groups. The current (Dutch) legal status of people with intellectual disabilities and children with psychiatric problems is one in which too much attention is ...
Chen Lan L Orthopedic Surgery, Foot and Ankle Service, North Shore Medical Group, Evanston, IL 60201, - - 2012
Patient-reported outcome questionnaires such as the Foot and Ankle Outcome Score (FAOS) are useful in evaluating results after orthopedic interventions. However, despite being frequently used in the literature, its validity has not been established for forefoot disorders. Our study aimed to validate the FAOS for use in assessing outcomes of ...
Zarei-Mahmoudabadi A - - 2012
Nosocomial infections are usually acquired during hospitalization. Fungal infection of the urinary tract is increasing due to predisposing factors such as; antibacterial agents, indwelling urinary catheters, diabetes mellitus, long hospitalization, immunosuppressive agents, use of IV catheters, radiation therapy, malignancy. The aim of our study was to determine the prevalence of ...
Epstein Joel B JB City of Hope National Medical Center, Duarte, CA, - - 2012
The clinical oral examination (COE) is the criterion standard for the initial detection of oral lesions that harbor dysplasia or oral squamous cell carcinoma (OSCC) at an early stage when they are most treatable. The authors conducted a systematic review to assess the effectiveness of the COE in predicting histologic ...
Chimento Philip F - - 2012
We demonstrate partial conversion of circularly polarized light into orbital angular momentum-carrying vortex light with opposite-handed circular polarization. This conversion is accomplished in a novel manner using the birefringent properties of a circular subwavelength slit in a thin metal film. Our technique can be applied over a very wide range ...
He Jinsong - - 2012
The aim of this study was to investigate the correlation between breast cancer-specific gene 1 (BCSG1) and the effect of neoadjuvant chemotherapy (NAC) in patients with triple-negative breast cancer (TNBC). Real-time RT-PCR and immunohistochemistry were used to determine the expression of BCSG1 mRNA and protein levels of 32 TNBC patients ...
Roche Eric - - 2012
BACKGROUND: Payment of research participants helps to increase recruitment for research studies, but can pose ethical dilemmas. Research ethics committees (RECs) have a centrally important role in guiding this practice, but standardisation of the ethical approval process in Ireland is lacking. AIM: Our aim was to examine REC policies, experiences ...
Lim Lily Siok Hoon - - 2013
Prognosis studies provide important healthcare information. Clinicians use prognostic factors to predict disease progress, thus allowing individualization of disease management. Prognosis is the issue in many translational studies that aim to identify biomarkers to predict outcomes. In a clinical trial, researchers may use prognostic factors to sort patients into risk ...
Brener Loren - - 2012
People with hepatitis C virus (HCV) are a marginalised population that may experience discrimination in everyday contexts, including health-care, due to the association of HCV with injecting drug use. Stigma and discrimination are known to have a range of negative effects on people with HCV, including diminished quality of life ...
Lu Yan - - 2013
Von Hippel-Lindau (VHL) is a tumor suppressor that negatively regulates the production of angiogenic factors. Mutations in the VHL gene cause VHL syndrome, which is characterized by highly vascularized tumors. Here we report a c.464T>A mutation of the VHL gene in three patients with hemangioblastoma from a Chinese family. This ...
Zhou Chuang - - 2012
BACKGROUND: Presurgery serum osteopontin (OPN) level has been demonstrated to correlate to tumor recurrence and survival of hepatocellular carcinoma (HCC) patients. This study investigated the postoperative dynamic changes of serum OPN level and its clinical significance in HCC patients. METHODS: Presurgery serum OPN levels were measured by enzyme-linked immunosorbent assay ...
Sell U - - 2012
Facial impalement in childhood is very rare. In most cases, it is caused by accident. We present two young patients who suffered a facial impalement injury and were treated in the interdisciplinary emergency room of the University Hospital Bonn, Germany. The degree of injury could not be completely determined during ...
Humbert Marc - - 2012
The long-term prognosis for patients with pulmonary arterial hypertension (PAH) remains poor, despite advances in treatment options that have been made in the past few decades. Recent evidence suggests that World Health Organization functional class I or II patients have significantly better long-term survival rates than patients in higher functional ...
Callens Stefaan - - 2012
Personal health monitoring (PHM) can be defined as comprising all technical systems, processing, collecting, and storing of data linked to a person. PHM involves several legal issues that are described in this article. This article analyses firstly the short-term actions that are needed at the European level to allow personal ...
Anwar Khan P - - 2012
Candidiasis is a common opportunistic infection in HIV-infected patients. The spectrum of Candida infection is diverse, starting from asymptomatic colonization to pathogenicforms. The low absolute CD4+ T-lymphocyte count has traditionally been cited as the greatest risk factor for the development of Oropharyngeal Candidiasis and current guidelines suggest increased risk once ...
Zhu Zhaojie - - 2012
The spectra of Er<sup>3+</sup>:CaGdAlO<sub>4</sub> and Pr<sup>3+</sup>/Er<sup>3+</sup>:CaGdAlO<sub>4</sub> crystals were measured under the same conditions. With the presence of Pr<sup>3+</sup> ions, the intensities of the green, red upconversion and near-infrared emissions are dramatically reduced to 1/20, 1/150, and 1/8.5 of those for Er<sup>3+</sup>:CaGdAlO<sub>4</sub>. Furthermore, the lifetimes of I<sub>11/2</sub>4 upper and I<sub>13/2</sub>4 lower ...
Yang Yuanjie - - 2012
By analysis of the far-field cross-correlation function (CCF) of partially coherent optical beams, we demonstrate an implicit rule that the number of ring dislocations (dark zones) of the far-field CCF is equal to the original topological charge of an optical vortex rendered partially coherent. This novel link between an optical ...
Glozier Nicholas - - 2012
OBJECTIVE The authors evaluated management of illness, including access to specialist mental health care, among people identified by general practitioners as clinically depressed. METHODS Australian primary care practitioners recruited in 2009 completed case reports and collected self-report assessments from five to seven consecutively presenting patients whom they identified as having ...
Yang Shu-Hua - - 2012
Although progress has been made to reduce global incidence of drug-susceptible tuberculosis, the emergence of multidrug-resistant (MDR) and extensively drug-resistant (XDR) tuberculosis (TB) during the past decade threatens to undermine these advances. XDR-TB has been found to be associated with scarce therapeutic options and high mortality rates. We describe the ...
Wang Zi - - 2012
In the clinical setting, drug resistance remains a significant obstacle for successful chemotherapy. Bcl-2/adenovirus EIB 19-kDa-interacting protein 3 (BNIP3) is a proapoptotic member of the Bcl-2 family. To address its potential as a therapeutic target for chemosensitisation, this study investigated the effect of BNIP3 expression on chemosensitivity and reversal of ...
Dobos Judit - - 2012
The possibility that endocrine factors may influence the clinical course of malignant melanoma is suggested by the superior survival data of women. In preclinical models we observed a higher rate of colony formation by human melanoma cells in male compared to female SCID mice, but only in the case of ...
Fernández-Sordo Jacobo Ortiz - - 2012
Endoscopic ultrasound (EUS) is considered the most accurate tool for the TNM staging of esophageal cancer, but its role in early Barrett's neoplasia is still debatable. The aim was to evaluate the utility of EUS in Barrett's patients prior to therapy. Retrospective review of 109 patients enrolled in a treatment ...
Murakami Tadahiro - - 2012
Cardiac papillary fibroelastoma is an uncommon tumor, and especially the one located in the left ventricular outflow tract wall is rare. The patient is a 69-year-old female. Multi-detector-row computed tomography (MDCT) revealed a 20×15 mm tumor attached to the left ventricular outflow tract wall under the left coronary cusp. The ...
Nophawan B - - 2012
Based on the current forensic importance of blow flies (Diptera: Calliphoridae), their biological aspects have been studied increasingly worldwide. The blow fly fauna in Phitsanulok Province, Northern Thailand was studied from May 2009 to April 2010 in the residential, agricultural, mountainous and forested areas of Muang, Wat Bot, Nakhon Thai ...
Kushida Clete A - - 2012
To determine the neurocognitive effects of continuous positive airway pressure (CPAP) therapy on patients with obstructive sleep apnea (OSA). The Apnea Positive Pressure Long-term Efficacy Study (APPLES) was a 6-month, randomized, double-blind, 2-arm, sham-controlled, multicenter trial conducted at 5 U.S. university, hospital, or private practices. Of 1,516 participants enrolled, 1,105 ...
- - 2012
In his regular update for Veterinary Record, Nigel Gibbens, the UK Chief Veterinary Officer, revisits the basis for the proposed badger culling policy and provides an overview of other current issues, including surveillance for Schmallenberg virus, dealing with equine infectious anaemia and the UK's stance on proposed changes to EU ...
Stang Andreas - - 2012
Several studies have assessed the association between midday nap and cardiovascular outcomes and reported heterogenous results. Concern exists that confounding might have distorted these results and contributed to discrepancies among them. This study prospectively examines the association between midday nap habits and the occurrence of coronary artery disease in a ...
Chaudhury Srabanti - - 2012
We consider a generic stochastic model of ion transport through a single channel with arbitrary internal structure and kinetic rates of transitions between internal states. This model is also applicable to describe kinetics of a class of enzymes in which turnover events correspond to conversion of substrate into product by ...
Maser Edmund - - 2012
ABSTRACT: The 16th International Meeting on the Enzymology and Molecular Biology of Carbonyl Metabolism, Castle of Ploen (Schleswig-Holstein, Germany), July 10--15, 2012, covered all aspects of NAD(P)-dependent oxido-reductases that are involved in the general metabolism of xenobiotic and physiological carbonyl compounds. Starting 30 years ago with enzyme purification, structure elucidation ...
de Ronde Jorma J - - 2013
Response rates to chemotherapy remain highly variable in breast cancer patients. We set out to identify genes associated with chemotherapy resistance. We analyzed what is currently the largest single-institute set of gene expression profiles derived from breast cancers prior to a single neoadjuvant chemotherapy regimen (dose-dense doxorubicin and cyclophosphamide). We ...
Wu Chuan - - 2012
Glyoxalase I is the first enzyme of the glyoxalase system that can detoxify methylglyoxal, a cytotoxic compound increased rapidly under stress conditions. Here we report cloning and characterization of a glyoxalase I from sugar beet M14 line (an interspecific hybrid between a wild species Beta corolliflora Zoss and a cultivated ...
Bast F - - 2012
Osteonecrosis of the mandible is a well-known and dreaded complication after the administration of bisphosphonates. Only a few cases of bisphosphonate-associated osteonecrosis of the external ear canal have been described. Especially after long-lasting bisphosphonate therapy, for example in patients with multiple myeloma, an ulceration of the floor of the bony ...
Wolff Jason J - - 2012
How does the behavioral expression of autism in fragile X syndrome (FXS + Aut) compare with idiopathic autism (iAut)? Although social impairments and restricted, repetitive behaviors are common to these variants of autism, closer examination of these symptom domains may reveal meaningful similarities and differences. To this end, the specific behaviors comprising ...
Kapusta Livia - - 2012
Data on myocardial deformation during the internationally widely used second-trimester screening are scarce and confusing. Reference values of time to peak strain are missing. The aims of this study were to assess reference values derived from two-dimensional speckle-tracking echocardiography for global and regional longitudinal right ventricular (RV) and left ventricular ...
Ning Song-Yi - - 2012
To investigate the effects of Liangxuehuayu Recipe on hemorheology in rats with blood stasis syndrome induced by mutifactor stimuli. SD rats were divided into control, model, Liangxuehuayu Recipe (high, middle and low dose, 18, 9, 4.5 g/kg accordingly). Except the control group, blood stasis model was established in the rest ...
Guo Zi-Yi - - 2012
To evaluate the anatomical characteristics and patterns of neurovascular compression in patients suffering trigeminal neuralgia, using 3D high-resolution magnetic resonance imaging methods and fusion technologies. The analysis of the anatomy of the facial nerve, brain stem and the vascular structures related to this nerve was made in 100 consecutive patients ...
Lousteau Joris - - 2012
We report on the fabrication and optical assessment of an all-solid tellurite-glass photonic bandgap fiber. The manufacturing process via a preform drawing approach and the fiber characterization procedures are described and discussed. The fiber exhibits some minor morphological deformations that do not prevent the observation of optical confinement within the ...
Konoeda Chihiro - - 2012
The patient was a 17-year-old girl. She underwent treatment for osteosarcoma when she was around 10 ~ 11 years old. A follow-up chest computed tomography(CT) revealed one small pulmonary nodule 6 years later. The orthopedist thought it was metastasis. The patient was referred to our division and treated with thoracoscopic ...
Mohammadi A - - 2012
Bluetongue virus (BTV) is a member of the genus Orbivirus in the family Reoviridae which is transmitted by insects and could cause considerable damages in sheep and goat flocks, such as mortality, decreased production and fertility, medical costs and commercial limits for flocks and their biologic production. As no study ...
Chan Wai Ting WT Centro de Investigaciones Biológicas, Consejo Superior de Investigaciones Científicas, Madrid, - - 2012
Pneumococcal infections cause up to 2 million deaths annually and raise a large economic burden and thus constitute an important threat to mankind. Because of the increase in the antibiotic resistance of Streptococcus pneumoniae clinical isolates, there is an urgent need to find new antimicrobial approaches to triumph over pneumococcal ...
Tsai Jinn-Tsong - - 2012
PURPOSE: The goal was to develop models for predicting long-term quality of life (QOL) after breast cancer surgery. METHODS: Data were obtained from 203 breast cancer patients who completed the SF-36 health survey before and 2 years after surgery. Two of the models used to predict QOL after surgery were artificial ...
Bhowmik B - - 2012
AIMS: To evaluate HbA(1c) as a tool for the diagnosis of diabetes and pre-diabetes (impaired glucose tolerance and/or impaired fasting glucose) and to identify the optimal cut-off values suitable for a Bangladeshi population. METHODS: In this cross-sectional survey in a rural community, 2293 randomly selected individuals aged ≥ 20 years without prior ...
Patel Dhaval - - 2012
Plants detect the presence of neighbouring vegetation through monitoring changes in the ratio of red (R) to far-red (FR) wavelengths (R:FR) in ambient light. Reductions in R:FR are perceived by the phytochrome family of plant photoreceptors and initiate a suite of developmental responses termed the shade avoidance syndrome. These include ...
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