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Choi Mi-Ran - - 2012
As systemic cancer therapies improve and are able to control metastatic disease outside the central nervous system, the brain is increasingly the first site of relapse. The blood-brain barrier (BBB) represents a major challenge to the delivery of therapeutics to the brain. Macrophages originating from circulating monocytes are able to ...
Føreland Solveig - - 2012
INTRODUCTION: The aim of this study was to identify important determinants of dust exposure in the Norwegian silicon carbide (SiC) industry and to suggest possible control measures. METHODS: Exposure to total dust, respirable dust, quartz, cristobalite, SiC, and fiber was assessed in three Norwegian SiC plants together with information on ...
Viana Pedro Couto - - 2012
Rehabilitating anterior edentulous areas can be a challenge for clinicians when there is a loss of hard and soft tissues. The authors present an innovative approach to manage these cases. Case 1 involved a patient with a dental implant placed in the position of tooth no. 7 and a loss ...
Wang Zhen - - 2012
ABSTRACT. Cerebral blood flow (CBF) is critical for the maintenance of cerebral function by guaranteed constant oxygen and glucose supply to brain. Collateral channels (CCs) are recruited to provide alternatives to CBF to ischemic regions once the primary vessel is occluded during ischemic stroke. However, the knowledge of the relationship ...
Okazaki Yoshikazu - - 2012
Coronary aneurysms in adults are rare. The natural history of such coronary aneurysms is unknown. Surgical treatment is often concomitant with the treatment of obstructive coronary lesions. However, the ideal treatment strategy is poorly defined. We herein present a case of successful treatment of a large coronary artery aneurysm with ...
Forbes Jonathan A - - 2012
Object The authors' goal was to better define the relationship between biomechanical parameters of a helmeted collision and the likelihood of concussion. Methods The English-language literature was reviewed in search of scholarly articles describing the rotational and translational accelerations observed during all monitored impact conditions that resulted in concussion at ...
Myers Nicholas D - - 2012
The purpose of this multistudy report was to develop, and then to provide initial validity evidence for measures derived from, the Referee Self-Efficacy Scale. Data were collected from referees (N = 1609) in the United States (n = 978) and Spain (n = 631). In Study 1 (n = 512), ...
Varisli Lokman - - 2012
The family with sequence similarity 83, member D (Fam83D) encodes a mitotic spindle-associated protein. Its knockdown results in shorter spindles that fail to organize a correct metaphase plate. In this study, we demonstrated that Fam83D is coexpressed with well-known mitotic genes. Pathway analysis results also showed that cell cycle- and ...
Zhao Kunpeng - - 2012
The tumor necrosis factor-related apoptosis-inducing ligand (TRAIL/Apo2L) is a novel cytotoxic ligand belonging to the TNF superfamily which is currently being developed as a cancer therapeutic drug. Here, we observed the different functions of recombinant TRAIL protein with a foreign protein label and non-labeled TRAIL. We used a prokaryotic expression ...
Vaitkus Saulius - - 2012
The objective of this study was to perform translation, cross-cultural adaptation, and validation of the SNOT-22 in the Lithuanian language. This is a prospective case-control study. The study was conducted at the University clinic. The sino-nasal outcome test 22 (SNOT-22) was translated into the Lithuanian language; the pilot study involved ...
Boch Steffen - - 2012
Endozoochory plays a prominent role for the dispersal of seed plants, and dispersal vectors are well known. However, for taxa such as ferns and bryophytes, endozoochory has only been suggested anecdotally but never tested in controlled experiments. We fed fertile leaflets of three ferns and capsules of four bryophyte species ...
Bücheler B M - - 2012
Quality of life is extraordinary affected by malignant tumors of the head and neck region as functions of social interaction are disturbed. The influence of surgical treatment and postoperative radio(chemo)therapy (RCT) on the quality of life was studied in patients with head and neck cancer. Twenty patients treated with curative ...
Sargsyan Armen - - 2012
N-type resonances excited in rubidium atoms confined in micrometric-thin cells with variable thickness from 1 μm to 2 mm are studied experimentally for the cases of a pure Rb atomic vapor and of a vapor with neon buffer gas. Good contrast and narrow linewidth were obtained for thicknesses as low as 30 μm. ...
Zhao Min - - 2012
Merkel cell carcinoma (MCC) is a rare malignant skin neoplasm with the potential for local recurrence, spreading to regional lymph nodes (LNs) and distant metastases. Although it has been identified in various anatomical sites, LN metastatic MCC in the absence of a primary site is extremely rare. The present case ...
Mayevsky Avraham - - 2012
Normal mitochondrial function in the process of metabolic energy production is a key factor in maintaining cellular activities. Many pathological conditions in animals, as well as in patients, are directly or indirectly related to dysfunction of the mitochondria. Monitoring the mitochondrial activity by measuring the autofluorescence of NADH has been ...
Park Seon-Joo - - 2012
This study investigated the anti-obesity effects of Jeju ground water containing the vanadium components S1 (8.0 ± 0.9 μg/l) and S3 (26.0 ± 2.09 μg/l) on the differentiation of 3 T3-L1 preadipocytes and obesity in mice that were fed a high-fat diet (HFD). The 3 T3-L1 preadipocyte cells were cultured and differentiated in media consisting of Jeju ground ...
Hoeck Sarah - - 2012
OBJECTIVES: To explore the existence of socioeconomic differences in probability and intensity of general practitioner (GP) and specialist contacts among the Belgian elderly population, compared with the younger population. METHODS: A nationally representative cross-sectional study based on 4,825 older (≥65) and 14,738 younger participants (<65) in the Belgian Health Interview ...
Rahman Luthfur - - 2012
Polyethylene wear is an important factor in failure of total hip arthroplasty (THA). With increasing numbers of THAs being performed worldwide, particularly in younger patients, the burden of failure and revision arthroplasty is increasing, as well, along with associated costs and workload. Various radiographic methods of measuring polyethylene wear have ...
Jeong Hyun-Woo - - 2012
In order to achieve computationally efficient mirror image rejection during the off-pivot, full-range approach in spectral-domain optical coherence tomography, we used a vestigial sideband (VSB) filter in place of a Hilbert transform. The appropriate choice of the VSB filter parameters enabled almost complete removal of one sideband with much reduced ...
Preciado Miguel A - - 2012
A novel (to our knowledge) kind of Airy-based pulse with an invariant propagation in lossy dispersive media is proposed. The basic principle is based on an optical energy trade-off between different parts of the pulse caused by the chromatic dispersion, which is used to compensate the attenuation losses of the ...
Kim Jong-Hyun - - 2012
Naegleria fowleri, free-living amoeba, has been found in diverse habitats throughout the world. It causes primary amoebic meningoencephalitis in children and young adults. The amoeba attaches to nasal mucosa, migrates along olfactory nerves, and enters the brain. Astrocytes are involved in the defense against infection and produce inflammatory responses. In ...
Leung Henry Wc - - 2012
Objective: To investigate whether the use of statins is associated with common cancer risk. Methods: A population-based case-control study was conducted in Taiwan. Cases were defined as all patients who were aged 18 years and older and had received at least two statin prescriptions for use continuously for at least ...
Ahmed Ahmed - - 2012
Orbital meningoceles and encephaloceles are rare extracranial extensions of the brain and meninges with or without direct communication between the central nervous system and the abnormal mass. We reported a rare case of large fetal orbital encephalocele; the diagnosis was suspected initially by prenatal ultrasound and confirmed by postnatal MRI ...
Hoth S - - 2012
This paper presents the recommendations compiled by the German Electric Response Audiometry Working Group (Arbeitsgruppe Elektrische Reaktions-Audiometrie, AGERA) and the Association of German Audiologists and Neuro-otologists (Arbeitsgemeinschaft Deutschsprachiger Audiologen und Neurootologen, ADANO) for infants that fail newborn hearing screening (NHS) tests. Outlined are procedures for follow-up diagnosis using objective hearing ...
Uchida Tetsuro - - 2012
To minimize the risk of malperfusion, axillary arterial cannulation which avoids retrograde flow, has been widely used in patients undergoing operations for various types of aortic pathologies. Despite several advantages of this technique, cerebral malperfusion is getting known and might be due to newly developed arterial damage or dissection. Eighty-four ...
Pang Shuo - - 2012
Here we report a low-cost and simple wide field-of-view (FOV) on-chip fluorescence-imaging platform, termed fluorescence Talbot microscopy (FTM), which utilizes the Talbot self-imaging effect to enable efficient fluorescence imaging over a large and directly scalable FOV. The FTM prototype has a resolution of 1.2 μm and an FOV of 3.9  mm×3.5  mm. We ...
Constantine Robert - - 2012
OBJECTIVE This study assessed the impact of a prior-authorization process on the use of antipsychotic medications by children under six years old in Florida's fee-for-service Medicaid program. METHODS Child psychiatrists reviewed requests for antipsychotic treatment (N=1,424) using forms and criteria created by a panel of Florida-based experts. Data on the ...
Sahraei R - - 2012
A new spectrophotometric method is reported for the determination of nanomolar level of malachite green in surface water samples. The method is based on the catalytic effect of silver nanoparticles on the oxidation of malachite green by hexacyanoferrate (III) in acetate-acetic acid medium. The absorbance is measured at 610 nm with ...
Nickel Anja - - 2012
For the development of nanoscale devices, the manipulation of single atoms and molecules by scanning tunneling microscopy is a well established experimental technique. However, for the construction of larger and higher order structures, it is important to move not only one adsorbate, but several at the same time. Additionally, a ...
Olszanecka-Glinianowicz Magdalena - - 2012
OBJECTIVE: The aim of the study was to analyze relationships between plasma apelin-36 and apelin-12 levels, nutritional status, insulin resistance and hormonal disturbances, as well as plasma adiponectin, leptin, and resistin concentrations in PCOS women. STUDY DESIGN PATIENTS AND MEASUREMENTS: A cross-sectional study involving 87 PCOS (48 obese) and 67 ...
Glien A - - 2012
Mesenchymal chondrosarcoma (MSC) is a very rare sarcoma that is highly malignant with frequent local recurrences and distant metastases leading to a very poor long-term outcome. It differs from classical chondrosarcomas in that it occurs more often in children and commonly in extraskeletal locations. Hardly any evidence-based recommendations for treatment ...
Young Heather - - 2012
Mycoplasma hominis is a bacteria that colonizes and infects the genitourinary tract; extragenital infections are not common. Three surgical site infections because of M hominis in immunocompetent adult trauma patients were detected at our facility in a 6-month time period. We investigated this case series and hypothesize transmission based on ...
Saffari Mohsen - - 2012
Avicenna, a renowned Persian Muslim scientist has written numerous scientific papers and valuable medical books that are respected worldwide. For centuries his masterpiece, the "Canon of Medicine", has been used as a major medical reference. The Canon, as a prime encyclopedia on medicine is comprised of five books. In the ...
Mas David - - 2012
Subpixel methods increase the accuracy and efficiency of image detectors, processing units, and algorithms and provide very cost-effective systems for object tracking. Published methods achieve resolution increases up to three orders of magnitude. In this Letter, we demonstrate that this limit can be theoretically improved by several orders of magnitude, ...
Nguyen Dat - - 2012
A fiber-based chirped-pulse amplification (CPA) system with an active feedback loop for pulse shaping is experimentally demonstrated. A spectral processor is used in conjunction with a frequency-resolved optical gating measurement to produce high-quality pulses. Spectral phase and intensity shaping are utilized to generate a clean, high-contrast, transform-limited pulse with 15 dB ...
Matini M - - 2012
Infection with Trichomonas vaginalis, the causative agent of human urogenital infection, is the most prevalent nonviral sexually transmitted disease worldwide. In spite of the high prevalence and medical importance of trichomoniasis, there is little knowledge about genetic epidemiology and genetic characterisation of this parasite. For this purpose, a Single Stranded ...
Zhu Wenjun - - 2012
In order to systematically evaluate the influence of lymph nodes (LNs) in lymph node metastases (LNM) of hepatocellular carcinoma (HCC), we set up a new in vitro model in which Hca-F and Hca-P cells were cultured in medium containing lymph node homogenates (LNHs). Differential protein expression was measured by two-dimensional ...
Sasaki Hidefumi - - 2012
Inflammation plays key roles at various stages of tumor development, including invasion and metastasis. In mice, the angiopoietin-like protein (ANGPTL2) gene has been implicated in inflammatory carcinogenesis. ANGPTL2 mRNA expression was investigated by real-time polymerase chain reaction (RT-PCR) assay using LightCycler in surgically treated non-small cell lung cancer (NSCLC) cases. ...
Kolb Alexander - - 2012
BACKGROUND: The failure of total hip replacements because of wear, particle-induced osteolysis, and aseptic loosening has focussed interest on factors potentially affecting the rate of wear. In this context the effect of particle release from the bone-implant interface of cementless implants is poorly understood. The surface structure for bony ongrowth ...
Newcomb Christina J - - 2012
Elucidating the structural information of nanoscale materials in their solvent-exposed state is crucial, as a result, cryogenic transmission electron microscopy (cryo-TEM) has become an increasingly popular technique in the materials science, chemistry, and biology communities. Cryo-TEM provides a method to directly visualize the specimen structure in a solution-state through a ...
Casper Robert F - - 2012
The concept of using aromatase inhibitors in place of clomiphene citrate (CC) for ovulation induction was introduced >10 years ago; a brief history of its development is presented. Its worldwide usage for ovulation induction, including as an adjunct for intrauterine insemination and in vitro fertilization has occurred despite the absence of ...
Sitbon Olivier - - 2012
It is well established that the endothelin, nitric oxide and prostacyclin pathways play an important role in the development of pulmonary arterial hypertension (PAH). Indeed, the therapeutic options currently available for the management of PAH all act on one of these mechanistic pathways. However, this is an exciting time for ...
Serebryannikov Andriy E - - 2012
Wideband suppression of zero order and relevant strongly asymmetric transmission can be obtained in photonic crystal gratings that are made of linear isotropic materials and show the broken structural (axial) symmetry, even if zero diffraction order may be coupled to a Floquet-Bloch (FB) wave at the incidence and exit interfaces. ...
Hao Jiaming - - 2012
In this Letter, we present a new type of ultrathin antireflection transparent and high-conductive screen based on plasmonic nanostructures that does not suffer from high loss and thickness coating and also can be used as good conductive material due to super electrical conductivity of the component (noble metal). Low reflection ...
Kawahito Tomohisa - - 2012
Tracheo-innominate artery fistula (TIF) is a rare but fatal complication after tracheostomy. Necessary lifesaving measures include proper ventilation, temporary hemostasis, and surgery. Recently, we successfully managed 3 cases of TIF. Ventilation and temporary hemostasis were secured by a long endotracheal tube and overinflated cuff. Division of the innominate artery, restoration ...
Koutras Georgios - - 2012
PURPOSE: Several studies have suggested that drilling the femoral tunnel through an anteromedial arthroscopic portal during anterior cruciate ligament reconstruction allows more anatomic placement of the graft. However, no studies have investigated whether the anteromedial approach results in better outcomes compared to the traditional transtibial drilling approach when a hamstring ...
Birau Amalia - - 2012
Despite advances in treatment, the prognosis for lung cancer patients remains poor. Angiogenesis appears to be a promising target for lung cancer therapy; however, the clinical significance of vascular changes are not completely understood. The aim of this study was to evaluate the types and morphology of blood vessels in ...
Sell U - - 2012
Facial impalement in childhood is very rare. In most cases, it is caused by accident. We present two young patients who suffered a facial impalement injury and were treated in the interdisciplinary emergency room of the University Hospital Bonn, Germany. The degree of injury could not be completely determined during ...
Callens Stefaan - - 2012
Personal health monitoring (PHM) can be defined as comprising all technical systems, processing, collecting, and storing of data linked to a person. PHM involves several legal issues that are described in this article. This article analyses firstly the short-term actions that are needed at the European level to allow personal ...
Zhu Zhaojie - - 2012
The spectra of Er<sup>3+</sup>:CaGdAlO<sub>4</sub> and Pr<sup>3+</sup>/Er<sup>3+</sup>:CaGdAlO<sub>4</sub> crystals were measured under the same conditions. With the presence of Pr<sup>3+</sup> ions, the intensities of the green, red upconversion and near-infrared emissions are dramatically reduced to 1/20, 1/150, and 1/8.5 of those for Er<sup>3+</sup>:CaGdAlO<sub>4</sub>. Furthermore, the lifetimes of I<sub>11/2</sub>4 upper and I<sub>13/2</sub>4 lower ...
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