Search Results
Results 551 - 600 of 3799
< 7 8 9 10 11 12 13 14 15 16 17 >
Mendes Olga Castro - - 2012
BACKGROUND: Physical stress tolerance (ST) is a measurement of cardiorespiratory fitness. Aerobic capacity is reduced in heart failure (HF) although there is no data available on this parameter in animals with ventricular dysfunction and no signs of HF. OBJECTIVE: Evaluate ST in rats with ventricular diastolic dysfunction isolated or associated ...
Daszkowska-Golec Agata - - 2013
Although the importance of abscisic acid (ABA) in plant development and response to abiotic and biotic stresses is well recognized, the molecular basis of the signaling pathway has not been fully elucidated. Mutants in genes related to ABA are widely used as a tool for gaining insight into the mechanisms ...
Rekhtman Natasha N Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA. - - 2013
Pulmonary large-cell carcinoma-a diagnostically and clinically controversial entity-is defined as a non-small-cell carcinoma lacking morphologic differentiation of either adenocarcinoma or squamous cell carcinoma, but suspected to represent an end stage of poor differentiation of these tumor types. Given the recent advances in immunohistochemistry to distinguish adenocarcinoma and squamous cell carcinoma, ...
Warner Daniel A - - 2012
Orientation and dispersal to suitable habitat affects fitness in many animals, but the factors that govern these behaviors are poorly understood. In many turtle species, hatchlings must orient and disperse to suitable aquatic habitat immediately after emergence from subterranean nests. Thus, the location of nest sites relative to aquatic habitats ...
Choi Hae-Yoon - - 2012
Past research has shown that emotion enhances true memory, but that emotion can either increase or decrease false memory. Two theoretical possibilities-the distinctiveness of emotional stimuli and the conceptual relatedness of emotional content-have been implicated as being responsible for influencing both true and false memory for emotional content. In the ...
Haase S - - 2012
The ability to design technological solutions that address sustainability is considered pivotal to the future of the planet and its people. As technology professionals engineers are expected to play an important role in sustaining society. The present article aims at exploring sustainability concepts of newly enrolled engineering students in Denmark. ...
Toth Peter - - 2012
BACKGROUND AND PURPOSE: Hypertension increases cerebrovascular oxidative stress and inflammation and impairs vasomotor function. These pathological alterations lead to dysregulation of cerebral blood flow and exacerbate atherogenesis, increasing the morbidity of ischemic cerebrovascular diseases and promoting vascular cognitive impairment. We aimed to test the hypothesis that increased production of the ...
Qi Delin - - 2012
The complete mitochondrial genome for Gymnocypris eckloni and Gymnocypris przewalskii ganzihonensis is 16,686 and 16,682 bp in size, respectively. Both of the mitochondrial genomes have identical genomic organization and structure including 13 protein-coding genes (PCGs), 22 tRNA genes, 2 rRNA genes and 1 control region as found in other vertebrates, with ...
Mayama Reiko - - 2012
Insulin-like growth factor-I (IGF-I) has been shown to stimulate extravillous trophoblast (EVT) cell migration and invasion, and to play a crucial role in placental function, thereby, influencing placental development and fetal growth. Insufficient invasion of EVT cells into the uterine endometrium leads to pregnancy-related complications, including spontaneous abortion, fetal growth ...
Schöll Hendrik - - 2012
PURPOSE: In the treatment of small bone fractures, such as the scaphoid bone, conventional navigation is limited by its dependence on fixed reference arrays. We introduce a new technique based on reference markers in surgical instruments. If visible on a standard fluoroscopic image, static trajectories are overlaid in this image ...
Yamamoto Shinya - - 2012
Notch signaling affects many developmental and cellular processes and has been implicated in congenital disorders, stroke, and numerous cancers. The Notch receptor binds its ligands Delta and Serrate and is able to discriminate between them in different contexts. However, the specific domains in Notch responsible for this selectivity are poorly ...
Kim Baik-Ho - - 2012
The removal or mitigation of cyanobacterial bloom and cyanotoxins is a necessity to ensure safe drinking water and recreational water. As a feasible agent to control cyanobacterial bloom, a novel plant-mineral composite (PMC) was developed and optimized through laboratory and field testing over the past 3 years. Based on previous studies, ...
Donohoe G - - 2012
Cognitive deficits are core to the disability associated with many psychiatric disorders. Both variation in cognition and psychiatric risk show substantial heritability, with overlapping genetic variants contributing to both. Unsurprisingly, therefore, these fields have been mutually beneficial: just as cognitive studies of psychiatric risk variants may identify genes involved in ...
Lu Zhuan-Ling - - 2012
Although rabies virus is widely distributed in the world, and has been the subject of extensive investigations with the objective of its ultimate prevention, control, and management, there is much less knowledge of the characteristics, distribution, and infectivity of other lyssaviruses. Since bats are known animal vectors for all but ...
Walker Robert - - 2012
This paper provides a detailed overview and discussion of anaesthesia in patients with mucopolysaccharidosis (MPS), the evaluation of risk factors in these patients and their anaesthetic management, including emergency airway issues. MPS represents a group of rare lysosomal storage disorders associated with an array of clinical manifestations. The high prevalence ...
Ferus Martin - - 2012
The formamide-based synthesis of nucleic acids is considered as a non-aqueous scenario for the emergence of biomolecules from inorganic matter. In the current study, we scrutinized the chemical composition of formamide ices mixed with an FeNi meteorite material treated with laser-induced dielectric breakdown plasma created in nitrogen buffer gas. These ...
Nkomazana Njabulo - - 2012
Summary Young people, especially university students, are at high risk of HIV infections because of little or no parental or administrative prohibitions in campus environments. The aim of this study was to ascertain the level of condom use among university students in Zimbabwe; that is, condom use at last sex ...
Gauthier A - - 2012
This article describes the adaptation of a model assessing the incidence of osteoporotic fractures and prevalence of postmenopausal osteoporosis (PMO) in Germany. PURPOSE: The purpose of this paper is to estimate the epidemiological burden of PMO in Germany from 2010 to 2020. METHODS: For each year of the study, the ...
Matsuoka Hiroaki - - 2012
Our objective was simply to report a sedge species, Carex kobomugi Ohwi that has beneficial bacterial associations under low Fe and P conditions of the Hasaki coast, Japan. C. kobomugi is the dominant species in our study area and grows closest to the sea. C. kobomugi showed higher Fe and P content, ...
Crida A - - 2012
When a planetary tidal disk--like Saturn's rings--spreads beyond the Roche radius (inside which planetary tides prevent aggregation), satellites form and migrate away. Here, we show that most regular satellites in the solar system probably formed in this way. According to our analytical model, when the spreading is slow, a retinue ...
Nakashima Ryoichi - - 2012
A common search paradigm requires observers to search for a target among undivided spatial arrays of many items. Yet our visual environment is populated with items that are typically arranged within smaller (subdivided) spatial areas outlined by dividers (e.g., frames). It remains unclear how dividers impact visual search performance. In ...
Joost Maximilian - - 2012
The reactivity of the amino(cyano)borane (i)Pr(2)NBH(CN) () towards [RuH(2)(η(2)-H(2))(2)(PCy(3))(2)] () was investigated. Our study reveals that the formation of the bis(isocyanoborane) ruthenium complex [RuH(CN)(CN-BHN(i)Pr(2))(2)(PCy(3))(2)] () occurs via the intermediacy of the bis(σ-B-H) ruthenium complex [RuH(CN)(H(2)BN(i)Pr(2))(PCy(3))(2)] (). This transformation involves BCN linkage isomerisation in . The diisopropylaminoborane ligand in can be ...
Gomery Kathryn - - 2012
Elucidation of protein structure using X-ray crystallography relies on the quality of the crystal. Crystals suffer from many different types of disorder, some of which occur during crystal nucleation and early crystal growth. To date, there are few studies surrounding the quality and nucleation of protein crystals partly due to ...
Tang Mingjie - - 2012
The molecular composition of mycobacteria and Gram-negative bacteria cell walls is structurally different. In this work, Raman microspectroscopy was applied to discriminate mycobacteria and Gram-negative bacteria by assessing specific characteristic spectral features. Analysis of Raman spectra indicated that mycobacteria and Gram-negative bacteria exhibit different spectral patterns under our experimental conditions ...
Shimada Toru - - 2012
We visualized the enhanced optical field distributions in one-dimensional linear array structures of gold nanospheres by using scanning near-field optical microscopy. The characteristic field distribution depends on the chain length of the one-dimensional structures. The distribution of optical field is reproduced qualitatively by model calculations based upon finite-difference time-domain (FDTD) ...
Nishigaki Akemi - - 2012
Stromal cell-derived factor-1 (SDF-1/CXCL12) and vascular endothelial growth factor (VEGF) are angiogenic factors that have possible roles in ovarian function. The objectives of this study were to investigate the association between the individual concentrations of SDF-1 and VEGF and sex steroid hormones in human preovulatory follicles and to verify the ...
Eickhoff Holger - - 2012
A technology for protein microarrays in 96 well microplates has been developed as a widely adoptable platform for multiplexed protein based diagnostics. Procedures for protein microarray manufacturing, immobilization, assay optimization and optical detection methods were developed. Using a clever combination of state of the art technologies, a versatile platform that ...
Simons Audrey Maria Wilhelmina - - 2012
OBJECTIVES: Because of their meritocratic ideology, Western countries might promote the belief that every individual is responsible for his or her socioeconomic position. These beliefs might enhance discrimination which, in turn, might affect health. Therefore, the aim of the study was to investigate the role of perceived discrimination within income-related ...
Tanaka Miyuki - - 2012
Self-quenching of the triplet excited state of thiobenzophenone ((3)TBP*) in molecular solvents, a sodium dodecyl sulfate (SDS) micellar solution, and ionic liquids (ILs) was measured using nanosecond laser flash photolysis. In the molecular solvents and ILs, (3)TBP* single-exponentially decayed, and the decay was accelerated with increasing TBP concentration. Self-quenching rate ...
van den Reek Juul - - 2012
Abstract Abstract To increase effectiveness of standard adalimumab treatment 40mg every other week (EOW) for patients with psoriasis, dose escalation to 40mg every week or addition of methotrexate (MTX) are possible strategies. Methods Daily practice data about adalimumab treatment were extracted from a prospective observational cohort. We analyzed all patients ...
Alikhani Zoubin - - 2012
OBJECTIVE: This study aims to optimize coronary sinus (CS) computerized tomography (CT) imaging and evaluate its utility for preprocedural planning and intraoperative guidance by overlay of 3D reconstructed CS images on live fluoroscopy. BACKGROUND: Optimal CS lead placement for cardiac resynchronization therapy (CRT) remains challenging. Preprocedural knowledge of CS anatomy ...
Verma M - - 2012
Asthma is a complex genetic disease, which arises from the interaction of multiple genes and environmental stimuli. These influences are important to asthma pathogenesis. These can be mechanically explained by the Epigenetic phenomenon, which consists of the chromatin and its modifications, as well as a covalent modification of cytosines residing ...
Direkvand-Moghadam A - - 2012
Introduction: Several risk factors have been used to predict preeclampsia. The role of some risk factors as predictors associated with preeclampsia among Iranian women was analyzed in the present study using logistic regression. Materials and Methods: 610 women attending the obstetric ward of Mustafa hospital in Ilam were enrolled in ...
Hur Yoon-Mi - - 2012
The South Korean Twin Registry (SKTR) is an ongoing nation-wide volunteer registry of South Korean twins and their families, which was established in the year 2001 to understand genetic and environmental etiologies of psychological and physical traits among South Koreans. Recently, the SKTR sampling has been extended in two important ...
Hardcastle Timothy Craig - - 2012
BACKGROUND: Trauma is one of the leading prehospital disease profiles in South Africa in general and in KwaZulu-Natal (KZN) in particular. The present study was designed to review the prehospital burden of injury in KZN, identify trauma burden to ambulance ratios, analyze system deficiencies, and propose a prehospital trauma system ...
Intartaglia R - - 2012
A picosecond laser ablation approach has been developed for the synthesis of ligand-free AuAg bimetallic NPs where the relative amount of Ag is controlled in situ through a laser shielding effect. Various measurements, such as optical spectroscopy, transmission electron microscopy combined with energy dispersive X-ray spectroscopy and inductively coupled plasma ...
Noguchi Masanori - - 2012
Since both tumor cells and host immune cell repertoires are diverse and heterogeneous, immune responses against tumor-associated antigens should differ substantially among individual cancer patients. Selection of suitable peptide vaccines for individual patients based on the preexisting host immunity before vaccination could induce potent anti-tumor responses that provide clinical benefit ...
Lee Sun Jae - - 2012
Abstract Objectives. To compare the efficacy of rescue therapies in lamivudine (LAM)-resistant chronic hepatitis B (CHB) infections including: (1) adefovir dipivoxil (ADV) monotherapy, (2) ADV plus LAM combination therapy and (3) entecavir (ETV) 1.0 mg monotherapy. Materials and methods. The authors designed a multicenter-retrospective study. Eight institutions participated in the ...
Wang Ah Rha - - 2012
In this study, the 17,694-bp long complete mitochondrial genome (mitogenome) of the dwarf honeybee, Apis florea (Hymenoptera: Apidae), was described, and a noteworthy triplicated tRNA(ser)(AGN) region and an extraordinary long A+T-rich region with repeat regions were identified. The gene arrangement of A. florea mitogenome was identical to that of Apis ...
Matsumoto K - - 2012
BACKGROUND: The natural history, including growth and rupture, of unruptured intracranial aneurysms (UIAs) remains unknown. Here, we present the results of serial magnetic resonance angiography (MRA) follow-up study in 111 patients with 136 UIAs. METHOD: A total of 111 patients with 136 UIAs were followed annually over the past 12 years, ...
Lovett Marlina - - 2012
Pulmonary artery sling is an incomplete vascular ring, the result of the left pulmonary artery arising from the right pulmonary artery and effectively constricting the airway, and it usually presents within the first weeks to months of life. We report a surgical correction of tracheal stenosis for a two-year-old patient ...
Casas-Fernández Carlos - - 2012
Background: The safety and effectiveness of lacosamide, an antiepileptic drug (AED) that selectively enhances the slow inactivation of voltage-gated sodium channels without affecting rapid inactivation, has been demonstrated in randomized, double-blind, placebo-controlled trials in adults with focal epileptic seizures. Although lacosamide is approved for use in patients over 16 years ...
Pelaia Girolamo - - 2012
Recent advances in the knowledge of asthma pathobiology suggest that biological therapies that target cytokines can be potentially useful for the treatment of this complex and heterogeneous airway disease. The use of biologics in asthma has been established with the approval of the humanized monoclonal immunoglobulin E-targeted antibody omalizumab (Xolair; ...
Williams Christopher C Department of Organic and Biological Chemistry, School of Chemistry, University of Bristol, Bristol BS8 1TS, - - 2012
Placental development and genomic imprinting coevolved with parental conflict over resource distribution to mammalian offspring. The imprinted genes IGF2 and IGF2R code for the growth promoter insulin-like growth factor 2 (IGF2) and its inhibitor, mannose 6-phosphate (M6P)/IGF2 receptor (IGF2R), respectively. M6P/IGF2R of birds and fish do not recognize IGF2. In ...
Xie Ping - - 2012
During DNA synthesis, high-fidelity DNA polymerase (DNAP) translocates processively along the template by utilizing the chemical energy from nucleotide incorporation. Thus, understanding the chemomechanical coupling mechanism and the effect of external mechanical force on replication velocity are the most fundamental issues for high-fidelity DNAP. Here, based on our proposed model, ...
Taneja A - - 2012
In spite of the evidence regarding high variability in the response to evoked pain, little attention has been paid to its impact on the screening of drugs for inflammatory and neuropathic pain. In this study, we explore the feasibility of introducing optimality concepts to experimental protocols, enabling estimation of parameter ...
Hatta Yoriko - - 2012
Pseudohypoaldosteronism type 1 (PHA1) is a rare condition characterized by neonatal salt loss with elevated plasma aldosterone and renin levels. Two types of PHA1 have been described: an autosomal recessive systemic form and an autosomal dominant renal form, in which the target organ defect is confined to the renal tubules. ...
Larsen Christopher P - - 2012
Autoantibody formation directed against phospholipase A2 receptor (PLA2R)1 is the underlying etiology in most cases of primary membranous glomerulopathy. This new understanding of the pathogenesis of primary membranous is in the process of transforming the way the disease is diagnosed. We validated an indirect immunofluorescence assay to examine PLA2R1 in ...
Schiller M - - 2012
High mobility group box protein B1 (HMGB1), a nuclear protein reportedly involved in the structural organisation of DNA, is released from necrotic cells or upon cellular activation. After its release into the extracellular space, HMGB1 serves as a mediator of inflammation. In contrast to necrotic cells, apoptotic ones usually do ...
Limaye Alpna R AR Section of Hepatobiliary Diseases, Department of Gastroenterology, Hepatology and Nutrition, University of Florida, Gainesville, Florida, - - 2013
The goal of this study is to evaluate whether an elevated neutrophil-lymphocyte ratio (NLR) at the time of diagnosis predicts survival of patients with hepatocellular carcinoma (HCC) after liver transplantation (LT). We hypothesize that the NLR is predictive of overall survival (OS) and recurrence-free survival (RFS) in patients with HCC ...
< 7 8 9 10 11 12 13 14 15 16 17 >