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Results 301 - 350 of 2474
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Joo Young-Chan - - 2012
PURPOSE: Chemical denervation is not recommended as part of the routine care of chronic non-cancer pain. Physicians face a dilemma when it comes to repeated interventions in cases of recurrent thoracolumbar facet joint pain after successful thermal radiofrequency ablation (RFA) in medial branch neurotomy. This study was performed to compare ...
Lee Yonghyun - - 2012
BACKGROUND: Co-administration of a reduction inhibitor and a colon-specific prodrug of a glucocorticoid susceptible to colonic reductive metabolism is suggested as a strategy to circumvent the therapeutic loss of the glucocorticoid delivered to and acting locally at the large intestine. AIMS: We examined whether the strategy was feasible as a ...
Mallia Pierre - - 2012
Some time ago an article was published in this journal relating the difficulties of legislating for InVitro Fertilization in a Catholic country and the issues and side issues which had to be faced. Since then one has approached closer to having a law which regulates this technology. However several issues ...
Hwang Sunyong - - 2012
We present high performance gas sensors based on an array of near single crystalline TiO(2) nanohelices fabricated by rotating oblique angle deposition (OAD). The combination of large surface-to-volume ratio, extremely small size (<30 nm) comparable to the Debye length, a near single crystallinity of TiO(2) nanohelices, together with the unique ...
Huis In 't Veld Elisabeth - - 2012
This study addresses two central and controversial issues in developmental prosopagnosia (DP), configuration- versus feature-based face processing and the influence of affective information from either facial or bodily expressions on face recognition. A sample of 10 DPs and 10 controls were tested with a previously developed face and object recognition ...
Rotili Dante - - 2012
Chemical changes performed on 1a (sirtinol) led to a series of SIRT1/2 inhibitors in some cases more potent than 1a mainly against SIRT1. Tested in human leukemia U937 cells, the benzamide and anilide derivatives 1b, 1c, 2b, and 2c as well as the 4-(2-phenylpropyl)thioanalogue 4c showed huge apoptosis induction, while ...
Peredo Elena L - - 2012
Although chloroplast transcriptional and translational mechanisms were derived originally from prokaryote endosymbionts, chloroplasts retain comparatively few genes as a consequence of the overall transfer to the nucleus of functions associated formerly with prokaryotic genomes. Various modifications reflect other evolutionary shifts toward eukaryotic regulation such as posttranscriptional transcript cleavage with individually ...
Kuipers Albertus F - - 2012
A 61-year-old man was referred to our hospital for evaluation of sleep apnea. He snored loudly and had apnea during sleep. During the day, he was sleepy, and when lying down, he could quickly fall asleep. He had a score of 15 on the Epworth Sleepiness Scale, which ranges from ...
Kolo Frank C - - 2012
OBJECTIVE: To determine the prevalence of femoroacetabular impingement (FAI) of the cam or pincer type based on magnetic resonance imaging (MRI) in a group of adult female professional ballet dancers, and to quantify, in vivo, the range of motion (ROM) and congruence of the hip joint in the splits position. ...
Terawaki Hiroyuki - - 2012
BACKGROUND: The present study aimed to clarify the beneficial effect of allopurinol on cardiovascular morbidity and mortality in a cohort of hypertensive nephropathy patients with impaired kidney function. METHODS: One hundred and seventy-eight patients diagnosed with hypertensive nephropathy and presenting with impaired kidney function (estimated glomerular filtration rate <45 mL/min/1.73 m(2)) were ...
Schumacher Soeren - - 2012
 : It is believed Lab-on-Chip systems will become a mainstream technology within the next centuries. Especially because of new findings in molecular medicine and global trends such as the changing global population in third world countries and an ageing population in industrial countries, the need for fast and reliable diagnostics ...
Laubscher Bernard - - 2012
In 2003, the Swiss guidelines to prevent vitamin K deficiency bleeding (VKDB) were adapted. As two oral doses (2 mg, hour/day 4) of mixed micellar VK preparation had failed to abolish late VKDB, a third dose (week 4) was introduced. This report summarizes the new guidelines acceptance by Swiss pediatricians and ...
Garcia A - - 2012
This work studies the morphological changes taking place in the goat omasum during prenatal development, using scanning electron microscope, light microscopy and immunohistochemical analysis. A total of 140 goat embryos and fetuses were used, from the first stages of prenatal life until birth. Differentiation of the omasum as a separate ...
Meek Heather - - 2012
This paper explores evolving treatments for hysteria in the eighteenth century by examining a selection of works by both physician-writers and educated literary women. The treatments I identify-which range from aggressive bloodlettings, diets, and beatings, to exercise, fresh air, and writing cures-reveal a unique culture of therapy in which female ...
Panizza Paola - - 2012
AIMS: Identification, cloning, expression and characterization of a novel lipase -Lip I.3- from strain Pseudomonas CR-611. METHODS AND RESULTS: The corresponding gene was identified and isolated by PCR-amplification, cloned and expressed in E. coli, and purified by refolding from inclusion bodies. Analysis of the deduced amino acid sequence revealed high ...
Fletcher Paul J - - 2012
RATIONALE: Depletion of brain serotonin (5-HT) results in impulsive behaviour as measured by increased premature responding in the five-choice serial reaction time (5-CSRT) test. Acute selective blockade of 5-HT(2C) receptors also increases this form of impulsive action, whereas 5-HT(2C) receptor stimulation reduces premature responding. OBJECTIVES: These experiments determined the impact ...
Ootes S T C - - 2012
Deinstitutionalisation has not only made the social inclusion of clients a key objective in long-term mental healthcare, it may also affect the role of the care professional. This article investigates whether the social inclusion objective clashes with other long-standing professional values, specifically when clients give gifts to care professionals. In ...
Georgiades Katholiki - - 2012
As levels of immigration and ethnic diversity continue to rise in most Western societies, the social demography of schools is changing rapidly. Although schools represent a prominent developmental context, relatively little is known about the extent to which the racial/ethnic composition of schools influences mental health outcomes in students. The ...
Huesmann Mario - - 2012
Background: Chronic cholestatic pruritus (ChP) is caused by various hepatobiliary disorders. This retrospective study describes the distribution of underlying diseases, clinical characteristics and treatment efficacy in a consecutive collective of patients with ChP. Patients and methods: Extensive data from 60 patients with ChP (30 women, 30 men; mean age: 58.0 ...
Schwarz Markus J - - 2012
Increased degradation of tryptophan (TRP) through the kynurenine (KYN) pathway (KP) is known to be involved in the molecular mechanisms resulting in the neuropathogenesis of Alzheimer's disease (AD). Activation of the KP leads to the production of neurotoxic metabolites 3-hydroxykynurenine (3-HK) and quinolinic acid (QUIN) by immune cells and neuroprotective ...
Gagne-Bourgue Francois - - 2012
AIMS: To isolate and characterize indigenous bacterial endophytes from cultivars of switchgrass and study their antimicrobial and growth promoting potential. METHODS AND RESULTS: The diversity, molecular and biochemical characterizations of indigenous and culturable bacterial endophytes residing in leaves of switchgrass have not been studied previoulsy. This paper describes the characterization ...
Zhang Yu - - 2012
BACKGROUND: Because of complicating anatomic factors, endoscopic submucosal dissection is seldom performed in subepithelial tumors of the esophagogastric junction originating from the muscularis propria layer. AIM: This study was designed to evaluate the feasibility of endoscopic muscularis excavation for treating subepithelial tumors of the esophagogastric junction originating from the muscularis ...
Riveros Fabián - - 2012
Biomechanical studies on abdominal aortic aneurysms (AAA) seek to provide for better decision criteria to undergo surgical intervention for AAA repair. More accurate results can be obtained by using appropriate material models for the tissues along with accurate geometric models and more realistic boundary conditions for the lesion. However, patient-specific ...
Li Chao - - 2012
Conventional reverse genetics for classical swine fever virus (CSFV) is based on the transfection of permissive cells with either in vitro or intracellularly synthesized RNA transcripts from a viral genomic cDNA clone. These strategies are complicated, inefficient and time-consuming. This study is aimed to develop an improved reverse genetics method ...
Lemnitzer Frederic - - 2012
The herpesvirus replication cycle comprises maturation processes in the nucleus and cytoplasm of the infected cells. After their nuclear assembly viral capsids translocate via primary envelopment towards the cytoplasm. This event is mediated by the nuclear envelopment complex, which is composed by two conserved viral proteins belonging to the UL34 ...
Schlieper Georg - - 2012
To the Editor: Olesen et al. (Aug. 16 issue)(1) report that in their study, warfarin treatment was associated with a decreased risk of thromboembolic events among patients requiring renal-replacement therapy. In contrast, three large registry studies concluded that in patients with atrial fibrillation who were undergoing hemodialysis, warfarin was associated ...
Martínez-Costa C - - 2012
BACKGROUND: To analyse the psychometric properties of the structured Satisfaction Questionnaire with Gastrostomy Feeding (SAGA-8) in parents/caregivers of children with home enteral nutrition (HEN) by gastrostomy tube (GT). METHODS: Eighty-six caregivers (mothers) of paediatric patients with HEN by GT were recruited. Patients suffered from neurological disease (61.6%) and other chronic ...
Varkevisser Rosanne - - 2012
Drug-induced ion channel trafficking disturbance can cause cardiac arrhythmias. We showed that the antiprotozoic pentamidine decreased K(IR)2.x carried I(K1) current and that inhibiting protein degradation in the lysosome increased intracellular K(IR)2.1 levels. In this study, we aim to identify and then inhibit preceding steps in clathrin-mediated endocytosis of K(IR)2.1 to ...
Díaz-Caneja Covadonga M - - 2012
The aim of this study was to review current epidemiological data on the use of antidepressants in co-prescription with other psychotropic drugs in children and adolescents, as well as available efficacy and safety information. A Medline search from inception until February 2012 was performed to identify epidemiological and clinical studies, ...
Fulde Marcus - - 2012
Zoonotic infections caused by Streptococcus spp. have been neglected in spite of the fact that frequency and severity of outbreaks increased dramatically in recent years. This may be due to non-identification since respective species are often not considered in human medical diagnostic procedures. On the other hand, an expanding human ...
Weissenbacher Tobias - - 2012
PURPOSE: Pro-inflammatory immunity, either infectious or sterile-derived, is one of the major causes of preterm birth and associated with enhanced maternal and fetal morbidity and mortality. Diagnosing intrauterine inflammation at an early stage is tremendously important. Amniotic fluid interleukin (IL)-6 concentration is currently the most investigated diagnostic tool for detecting ...
Shakeel Muhammad - - 2012
Synthetic hexaploid (SH) wheat derived from crossing tetraploid durum wheat and diploid Aegilops tauschii provide germplasm for wheat improvement as the conventional wheat varieties possess very low genetic diversity. This study aims to identify diverse SH lines which can be used in breeding programs for transferring the desired traits into ...
Della Rocca G - - 2012
Sugammadex, the first selective relaxant-binding agent indicated to reverse the neuromuscular blockade induced during general anesthesia, was recently introduced into clinical practice. In the present report, the following issues pertinent to the use of sugammadex in anesthesia practice are discussed: the intraoperative use of NMBAs and the incidence of postoperative ...
González Cabrera Diego - - 2012
In an effort to address potential cardiotoxicity liabilities identified with earlier frontrunner compounds, a number of new 3,5-diaryl-2-aminopyridine derivatives were synthesized. Several compounds exhibited potent antiplasmodial activity against both the multidrug resistant (K1) and sensitive (NF54) strains in the low nanomolar range. Some compounds displayed a significant reduction in potency ...
Hughes-Davies Tom - - 2012
To the Editor: With regard to the article by Kelly et al. (Sept. 6 issue)(1): in principle, the children could become shorter adults because of therapy, as the authors conclude, or they could become taller because of continued wheezing. Height depends on shape as well as bone length. At rest, ...
Zong Wei - - 2012
Histone modifications affect gene expression level. Several studies have shown that they may play key roles in regulating gene expression in plants under abiotic stress, but genome-wide surveys of such stress-related modifications are very limited, especially for crops. By using ChIP-Seq and RNA-Seq, we investigated the genome-wide distribution pattern of ...
Haugaa Håkon - - 2012
Ischemic vascular complications and rejections occur more frequently in pediatric than adult liver transplants. Using intrahepatic microdialysis catheters we measured lactate, pyruvate, glucose, and glycerol bedside for a median of 10 days in 20 pediatric liver grafts. Ischemia (n=6) defined as lactate >3.0 mM and lactate/pyruvate ratio > 20, was ...
Sharifzadeh Mehdi - - 2012
Childhood ocular trauma is a preventable cause of visual impairment and blindness worldwide. This prospective study was conducted to explore the profile of eye injuries in pediatric patients referring to a tertiary eye center in Tehran, Iran. Six hundred consecutive pediatric patients aged 17 or less who presented to emergency ...
Sonnewald Uwe - - 2012
As the world's second most abundant biopolymer, starch serves as food, feed and renewable resource for bioenergy production and other industrial applications. Unlike storage lipids, starch is stored in the form of semi-crystalline granules, which are tissue- and species-specific in number, shape and size. Over the last decades, most biosynthetic ...
Carrion Iraida V - - 2012
PURPOSE: Limited knowledge exists pertaining to advance care planning (ACP) among Colombian, Mexican, and Puerto Rican women with a cancer diagnosis living in Central Florida, in the USA. The purpose of the study is to identify factors that facilitated the completion of ACP and decisions making patterns among the three ...
Kapoor Radhika - - 2012
Oxidative stress is implicated in hyperglycemia-induced alterations in cell signaling pathways. We examined the toxicity of high glucose in primary rat hepatocytes and its amelioration by naringenin. Incubation of hepatocytes with 40 mM glucose for 1.5 h exhibited significant decrease in cell viability confirmed by MTT reduction and Alamar blue assay. At ...
Chai Xiangfei - - 2012
The aim of this study is to develop a novel semiautomatic bladder segmentation approach for selecting the appropriate plan from the library of plans for a multiple-plan adaptive radiotherapy (ART) procedure. A population-based statistical bladder model was first built from a training data set (95 bladder contours from 8 patients). ...
Barakat Fareed H - - 2012
OBJECTIVES: Sentinel lymph node (SLN) examination in breast carcinoma is crucial to spare patients unnecessary lymph node (LN) dissection. The specificity and accuracy of SLN examination by frozen section has been variable in many studies. This study aims to describe our experience in frozen section (FS) analysis of SLN. METHODS: ...
Dignat G - - 2012
We have tested to what extent the growth ability of several organs of maize share a common genetic control. Leaf elongation rate reaches every night a maximum value (LER(max) ) that has a high heritability, is repeatable between experiments and is correlated with final leaf length. We first summarised QTLs ...
Mészáros Patrik - - 2012
The kinetics of defense responses was studied in soybean exposed to ecologically relevant concentrations of arsenic for 96 h. In the roots of two soybean cultivars with contrasting tolerance to this metalloid there were observed differences in basal levels of membrane lipid peroxidation as well as a significantly different course of ...
Yang Min - - 2012
Self-ordered TiO(2)/Nb(2)O(5) "superlattice" nanotube arrays are successfully fabricated by electrochemical anodization from a commercially available Ti-Nb metal multilayer. The oxide nanotube walls then consist of alternating ∼4 nm TiO(2) and ∼7 nm Nb(2)O(5) rings. Such "superlattice" nanotube layers exhibit a much higher structural cycling stability for reversible Li-intercalation processes than ...
Sood Manish M - - 2012
To the Editor: Olesen et al. (Aug. 16 issue)(1) report that in their study, warfarin treatment was associated with a decreased risk of thromboembolic events among patients requiring renal-replacement therapy. In contrast, three large registry studies concluded that in patients with atrial fibrillation who were undergoing hemodialysis, warfarin was associated ...
Dedzo Gustave Kenne - - 2012
A nanohybrid kaolinite material with anion exchange properties was obtained by the grafting of an ionic liquid in the interlayer spaces of kaolinite. It was used successfully for the amperometric detection of iodide in aqueous solution and tap water after a pre-concentration step, with a detection limit of 1.5 × ...
Whitaker Sean - - 2012
Violent conflict disrupts livelihoods, healthcare systems, and food security, with dire public health consequences. My intention in this article is to conceptualise violent conflict as a public health hazard and delineate the strategies public health professionals might adopt to minimise that hazard. There is continued support among commentators for the ...
Okita Keisuke - - 2012
The generation of induced pluripotent stem cells (iPSCs) provides the opportunity to use patient-specific somatic cells, which are a valuable source for disease modeling and drug discovery. To promote research involving these cells, it is important to make iPSCs from easily accessible and less invasive tissues, like blood. We have ...
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