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Results 201 - 250 of 2475
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Jolliffe Darrick - - 2012
Systematic reviews of the relationship between non-manipulated factors (e.g. low empathy) and offending are becoming more common, and it is important to consider the methodological quality of studies included in such reviews. To assess aspects of the reliability and validity of the Cambridge Quality Checklists, a set of three measures ...
Nijhawan Ank E AE Division of Infectious Diseases, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA. - - 2012
Trichomonas vaginalis is the most prevalent curable sexually transmitted infection in the United States and may lead to preterm delivery, infertility, and increased HIV transmission. Incarcerated women may be at especially high risk for infection, although few studies have examined routine screening for Trichomonas infection in this population. Women older ...
Lin Feng - - 2012
Mild cognitive impairment (MCI) is a mild decline in single or multiple cognitive domains, while global cognition and basic activities of daily living remain intact. Nurses play an important role in early detection of MCI and providing care to maintain maximum independence for individuals with MCI. This article seeks to ...
Wikström Erika - - 2012
In recent decades, increasing rates of Chlamydia cases have contrasted with decreasing Chlamydia trachomatis seroprevalence rates and decreasing Chlamydia-associated complication rates. We elucidated the conflicting trends by studying incidence of repeated Chlamydia infections over time. Chlamydia cases reported during 1995 to 2009 were identified in the Finnish National Infectious Diseases ...
Zheng Hong-Wei - - 2012
MicroRNAs have recently been shown to regulate the downstream bioprocesses of intracerebral hemorrhage. The aim of this study was to investigate whether miRNAs can be used as biomarkers to predict secondary hematoma enlargement (HE) in patients with ICH. Consecutively, 79 ICH patients admitted within 6 h of symptom onset and 30 ...
Buratti S - - 2012
Major malformations, surgery and persistent pulmonary hypertension (PHT) have been considered contraindications to therapeutic hypothermia (TH) in newborns with hypoxic-ischemic encephalopathy (HIE). We report two patients with undiagnosed congenital diaphragmatic hernia (CDH) who developed HIE after birth. Diagnosis of moderate HIE was formulated based on clinical, laboratory and electroencephalographic criteria. ...
Lequeux Charlotte C Department of Plastic Surgery, University of Texas Southwestern Medical Center, Dallas, Texas, USA. - - 2012
This pilot study examined the efficacy of 5-bromo-2-deoxyuridine-labeled autologous adipose-derived stem cells seeded onto collagen scaffolds to augment and/or regenerate the fat-enriched hypodermal tissue in an acute porcine wound model. Porcine autologous adipose-derived stem cells were isolated and cultured. At passage 2, the cells were labeled with 5-bromo-2-deoxyuridine, seeded onto ...
Sidler Jan A - - 2012
Viral nosocomial infections (NIs) in children are common and most frequently affect the gastrointestinal or respiratory tract. Few studies are dedicated to this topic. We aimed to determine incidence and characteristics of these specific viral NIs at our hospital. This was a retrospective analysis of nosocomial gastroenteritis and respiratory tract ...
Chignon-Sicard Bérengère B Plastic Reconstructive and Aesthetic Surgery Department, St Roch University Hospital of Nice, Nice, - - 2012
Application of platelet concentrates to wounds could speed healing. Leukocyte- and platelet-rich fibrin, a relatively recent development, stands out from the other preparations. This prospective, randomized, controlled clinical trial studied the rate of healing of postoperative hand wounds after a single application of leukocyte- and platelet-rich fibrin. Eligible patients were ...
Raymond H Fisher - - 2012
ABSTRACT: Serum specimens collected during the 2011 round of National HIV Behavioral Surveillance among men who have sex with men in San Francisco were tested for hepatitis C virus antibodies. Hepatitis C virus infection was found among men who have sex with men with a history of intravenous drug use ...
Yin Feng - - 2012
To assess the clinical effect of transplantation of human retinal pigment epithelial (hRPE) cells into the unilateral postcommissural putamen for treatment for Parkinson disease (PD). Cells from postmortem human eye tissue (10-20 weeks of gestation) were cultured in vitro. Cells from -generation passage were implanted in PD postcommissural putamen with stereotactic ...
Gallego Augusto Arias - - 2012
The use of monofocal, bifocal, or multifocal intraocular lenses (IOLs) is a common option to restore the refractive power of the eye in aphakic patients after cataract surgery. In this article, we study the predicted performance of two new designs of IOL, both with extended depth of focus: the quartic ...
Henderson Susan - - 2012
The passage of the Patient Protection and Affordable Care Act (ACA) of 2010 has helped reshape primary care by funding the development of care approaches that better integrate and coordinate services, such as the patient-centered medical home (PCMH). Primary care practices that adopt this model offer the comprehensive, patient-centered care ...
Haddock Nicholas T NT New York University Langone Medical Center, Institute of Reconstructive Plastic Surgery, New York, NY, USA. - - 2012
Free tissue transfer to improve bulk and contour in facial deformities has been proven useful, yet refinements that turn an acceptable result into an excellent result are essential to reconstruction. The authors reviewed their experience and described these refinements. The charts of 371 free tissue transfer cases (1989 to 2010) ...
Colohan Shannon S Department of Plastic Surgery, University of Texas Southwestern Medical Center at Dallas, Texas 75390, - - 2012
Increasing focus on reducing morbidity from latissimus dorsi flaps has led to the evolution of muscle-sparing variants and perforator-based flaps. This study aimed to investigate the vascular anatomy of the muscle-sparing variant and to describe its application as a free flap based on the descending branch of the thoracodorsal artery. ...
Shi Guohua - - 2012
ABSTRACT. In order to understand the relationship between accommodation and vision quality, a custom-built ultra-long scan depth spectral domain optical coherence tomography (UL-SDOCT) and a Shack-Hartmann wavefront sensor (HSWFS) were combined. The resolution and scan depth of UL-SDOCT are 6 μm and 15.6 mm, respectively, which allow for high-resolution imaging of the ...
Javanbakht Marjan - - 2012
The prevalence and correlates of rectal sexually transmitted infections are well described among men who report receptive anal intercourse (AI); however, little is known about the epidemiology of rectal sexually transmitted infections among women. We conducted a cross-sectional study of women attending public sexually transmitted disease clinics in Los Angeles ...
Aversa S - - 2012
Glucocorticoids (GCs) are considered drugs of choice for treating nasal polyps (NPs). However, a subset of patients shows a limited clinical response even to high doses of GCs. Altered expression of glucocorticoid receptors (GRs), namely GR-alpha; and GR-beta;, is a potential mechanism underlying GC insensitivity. GCs modulate the expression of ...
Margetić Branimir - - 2012
People who become patients in secure hospitals may not understand their situation and have different opinions about the nature of institutionalisation from each other and from staff and the authorities. More knowledge of patient perspectives could improve treatment outcomes. Our aim was to evaluate patients' beliefs about whether placement in ...
- - 2012
Background: In 2009, 6.7% of the estimated 1.1 million persons living with human immunodeficiency virus (HIV) infection in the United States were youths (defined in this report as persons aged 13-24 years); more than half of youths with HIV (59.5%) were unaware of their infection. Methods: CDC used National HIV ...
Wang Zhifu - - 2012
Sepsis represents a systemic inflammatory response to infection and its sequelae include severe sepsis, septic shock, multiple organ dysfunction syndrome (MODS) and death. Studies in mice and humans indicate that the inducible nitric oxide synthase (iNOS, NOS2) plays an important role in the development of sepsis and its sequelae. It ...
Atmaca Halil - - 2012
PURPOSE: Depending on the location and extent of the meniscectomy, loading on the tibial articular cartilage alters. The main purpose of the present study was to analyze the loading on the tibial articular cartilage following medial meniscectomy performed in various location and extent, as well as in the healthy knee, ...
Rosenow F - - 2012
The term non-convulsive status epilepticus (NCSE) refers to a heterogeneous group of diseases with different etiology, prognosis and treatment. The different forms of NCSE comprise about 25-50% of all status epilepticus cases. The most frequent form encountered in clinical practice is complex-partial SE but the rarer conditions of absence status, ...
Ahn Eu-Ree - - 2012
The forkhead-associated (FHA) domain is involved in protein-protein interaction by recognizing a phosphothreonine epitope on target proteins. In this study, we investigated in planta functions of the Arabidopsis FHA domain 2. AtFHA2 was mainly localized in the nucleus. Arabidopsis fha2 null mutants grew normally during the vegetative stage, but had ...
Chakrabarti Mrinmay - - 2012
Neuroblastoma is an extracranial solid tumor that usually occurs in infants and children. Malignant neuroblastomas remain mostly refractory to currently available chemotherapeutic agents. So, new therapeutic agents and their molecular mechanisms for induction of cell death must be explored for successful treatment of human malignant neuroblastomas. Two polyphenolic compounds, which ...
Trabert J - - 2012
Given the number of studies that have investigated the subject of intracerebral hemorrhage, there are still many research questions unanswered, including prevention and treatment of progressive hemorrhage, indications for surgical intervention, secondary prophylaxis and also treatment of intracerebral hemorrhage in patients with new anticoagulants. This article presents an overview of ...
Franz Maximilian B - - 2012
INTRODUCTION: The corpus luteum (CL), develops from the ruptured follicle after gonadotropin stimulation. Based on intracellular reorganization of the cytoskeleton an human chorionic gonadotropin (hCG) dependent sprouting and migration of luteinizing granulosa cells (LGCs) and endothelial cells is observed. Rho-GTPases are shown to be key regulators of cytoskeletal restructuring. In ...
Seideman Casey A - - 2012
Within the last decade, the adaptation of robotic urologic surgery has had a profound impact on surgical practice, with robotic upper tract reconstruction for ureteropelvic junction obstruction gaining rapid acceptance. Recent advances in robotic reconstruction demonstrate efficacious outcomes of robotic pyeloplasty, as compared with conventional laparoscopic pyeloplasty, even in the ...
Romero-Maroto M - - 2012
INTRODUCTION: Two processes of vastly different clinical characteristics-what we know today as "Aphthous Stomatitis" and "noma"-occupied the minds of dentists and doctors from the sixteenth to eighteenth centuries. The aim of this article was to look at their knowledge-concerning the differential diagnosis and treatment of these two processes. MATERIALS AND ...
Dekker Nicky - - 2012
Referral of patients with endometrial (EC) and/or ovarian cancer (OC) for genetic counseling is based on age at diagnosis and family history. Many patients with hereditary cancers are missed by following this strategy. We determined acceptance and mutation detection rate of offering genetic counseling and testing to unselected EC and ...
Dekate Parag - - 2012
Acute diarrhea is the second leading cause of under-five mortality in India. It is defined as the passage of frequent watery stools (>3/24 h). Recent change in consistency of stools is more important than frequency. Acute diarrhea is caused by variety of viral, bacterial and parasitic agents. The common ones are: ...
- - 2012
In 2007, the national prevalence of HIV in Kenya was 7.1% among persons aged 15-64 years, with provincial prevalence rates ranging from 0.8% in North Eastern Province to 14.9% in Nyanza Province. Although an estimated 85.0% of males in Kenya are circumcised, nearly half of all uncircumcised men live in ...
Saar Indrek - - 2012
Neuropeptide galanin and its three receptors, galanin receptor type 1-galanin receptor type 3, are known to be involved in the regulation of numerous psychological processes, including depression. Studies have suggested that stimulation of galanin receptor type 2 (GalR2) leads to attenuation of the depression-like behavior in animals. However, due to ...
Mazza Alberto - - 2012
The role of arterial hypertension (HT) as risk factor for Parkinson's disease (PD) is still debated. Case-control and retrospective studies do not support an association between HT and PD and the risk of PD seems to be lower in hypertensive than in normotensive subjects. In addition, the use of calcium-channel ...
- - 2012
The recycling of lead has increased during the past 20 years, with more workers and their families potentially being exposed to lead from recycling facilities, including facilities that recycle lead-acid batteries. During November 2010-May 2011, four voluntary blood lead screening clinics for children of employees of a battery recycling facility ...
Pastor Verónica V Department of Physiology and Institute of Cell Biology, School of Medicine, University of Buenos Aires, Paraguay 2155 7th floor, C1121A6B, Buenos Aires, - - 2013
Prior exposure to drugs of abuse may increase or decrease the reinforcing effects of the drug in later consumptions. Based on the initial locomotor activity (LA) response to an acute drug administration or to novelty in an open-field arena, animals can be classified as low or high LA responders (LR ...
Schwarz Frank - - 2012
PURPOSE: This case illustrates a pulp tissue-induced dentointegration of a titanium implant. MATERIALS AND METHODS: One commercially available titanium implant with a sand-blasted and acid-etched surface was placed in the maxilla of a foxhound where the palatinal root of the previously (i.e., 8 weeks) removed first molar was unintentionally retained. After ...
- - 2012
Human immunodeficiency virus (HIV) infections attributed to male-to-male sexual contact comprised 64% of the estimated new HIV infections in the United States in 2009. Assessing the geographic distribution of HIV infection by transmission category can help public health programs target prevention resources to men who have sex with men (MSM) ...
Humbert Ianessa A IA Department of Physical Medicine and Rehabilitation, Johns Hopkins University, School of Medicine, 98 North Broadway, Suite 409, Baltimore, MD 21231, - - 2013
Oropharyngeal swallowing is a complex sensorimotor phenomenon that has had decades of research dedicated to understanding it more thoroughly. However, the underlying neural mechanisms responsible for normal and disordered swallowing remain very vague. We consider this gap in knowledge the result of swallowing research that has been broad (identifying phenomena) ...
Alasker Ahmed - - 2012
An increasing number of small renal masses (SRMs) are being detected with modern cross-sectional imaging. The natural history of SRMs is mostly unknown. Initial active surveillance (AS) is a reasonable treatment option for small renal masses (SRMs) < 4 cm in the infirm patient with major comorbidities. Partial nephrectomy (PN) is the ...
Arthur Joseph G JG Department of Mathematics, North Carolina State University, Raleigh, NC, USA. - - 2013
We derive a formula that relates the spike-triggered covariance (STC) to the phase resetting curve (PRC) of a neural oscillator. We use this to show how changes in the shape of the PRC alter the sensitivity of the neuron to different stimulus features, which are the eigenvectors of the STC. ...
Schlieper Georg - - 2012
To the Editor: Olesen et al. (Aug. 16 issue)(1) report that in their study, warfarin treatment was associated with a decreased risk of thromboembolic events among patients requiring renal-replacement therapy. In contrast, three large registry studies concluded that in patients with atrial fibrillation who were undergoing hemodialysis, warfarin was associated ...
Boyd Suzanah C - - 2013
Approximately 50% of melanomas require oncogenic B-RAF(V600E) signaling for proliferation, survival, and metastasis, and the use of highly selective B-RAF inhibitors has yielded remarkable, although short-term, clinical responses. Reactivation of signaling downstream of B-RAF is frequently associated with acquired resistance to B-RAF inhibitors, and the identification of B-RAF targets may ...
Martínez-Costa C - - 2012
BACKGROUND: To analyse the psychometric properties of the structured Satisfaction Questionnaire with Gastrostomy Feeding (SAGA-8) in parents/caregivers of children with home enteral nutrition (HEN) by gastrostomy tube (GT). METHODS: Eighty-six caregivers (mothers) of paediatric patients with HEN by GT were recruited. Patients suffered from neurological disease (61.6%) and other chronic ...
Varkevisser Rosanne - - 2012
Drug-induced ion channel trafficking disturbance can cause cardiac arrhythmias. We showed that the antiprotozoic pentamidine decreased K(IR)2.x carried I(K1) current and that inhibiting protein degradation in the lysosome increased intracellular K(IR)2.1 levels. In this study, we aim to identify and then inhibit preceding steps in clathrin-mediated endocytosis of K(IR)2.1 to ...
Díaz-Caneja Covadonga M - - 2012
The aim of this study was to review current epidemiological data on the use of antidepressants in co-prescription with other psychotropic drugs in children and adolescents, as well as available efficacy and safety information. A Medline search from inception until February 2012 was performed to identify epidemiological and clinical studies, ...
Fulde Marcus - - 2012
Zoonotic infections caused by Streptococcus spp. have been neglected in spite of the fact that frequency and severity of outbreaks increased dramatically in recent years. This may be due to non-identification since respective species are often not considered in human medical diagnostic procedures. On the other hand, an expanding human ...
Weissenbacher Tobias - - 2012
PURPOSE: Pro-inflammatory immunity, either infectious or sterile-derived, is one of the major causes of preterm birth and associated with enhanced maternal and fetal morbidity and mortality. Diagnosing intrauterine inflammation at an early stage is tremendously important. Amniotic fluid interleukin (IL)-6 concentration is currently the most investigated diagnostic tool for detecting ...
Shakeel Muhammad - - 2012
Synthetic hexaploid (SH) wheat derived from crossing tetraploid durum wheat and diploid Aegilops tauschii provide germplasm for wheat improvement as the conventional wheat varieties possess very low genetic diversity. This study aims to identify diverse SH lines which can be used in breeding programs for transferring the desired traits into ...
Della Rocca G - - 2012
Sugammadex, the first selective relaxant-binding agent indicated to reverse the neuromuscular blockade induced during general anesthesia, was recently introduced into clinical practice. In the present report, the following issues pertinent to the use of sugammadex in anesthesia practice are discussed: the intraoperative use of NMBAs and the incidence of postoperative ...
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