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Results 701 - 750 of 2475
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Valli Veronica - - 2012
Molasses, the main byproduct of sugar production, is a well known source of antioxidants. In this study sugar cane molasses (SCM) and sugar beet molasses (SBM) were investigated for phenolic profile and in vitro antioxidant capacity, and for their protective effect in human HepG2 cells submitted to an oxidative stress. ...
Cheng Hsiu-Yao - - 2012
To investigate the resonance energies and lifetimes of temporary anion states of chloromethanes, long-range corrected density functional theory is adopted in this paper. Their values are determined by calculating the density of resonance states via the stabilized Koopmans' theorem. The characteristics of these resonance orbitals are also analyzed. By comparing ...
Puerto Galvis Carlos E - - 2012
An unexpected intramolecular cyclization during the reaction of furfurylamine with maleimides is reported as a novel strategy for the efficient green synthesis of the 7-oxa-2-azabicyclo[2.2.1]hept-5-ene skeleton. Under the same reaction conditions, 7-oxabicyclo[2.2.1]hept-5-enes were synthesized when furfurylamine was N-protected by the acetyl group. Both types of bicycloheptenes were screened using the ...
Banypersad Sanjay M SM The Heart Hospital, London, - - 2013
Cardiac involvement predicts outcome in systemic AL amyloidosis and influences therapeutic options. Current methods of cardiac assessment do not quantify myocardial amyloid burden. We used equilibrium contrast cardiovascular magnetic resonance (EQ-CMR) to quantify the cardiac interstitial compartment, measured as myocardial extracellular volume (ECV) fraction, hypothesizing it would reflect amyloid burden. ...
Barud W - - 2012
ABSTRACT Purpose: Many studies indicate an inverse relationship between stromal-derived factor-1 alpha (SDF-1 alpha), a chemokine, and coronary risk factors. Moreover, SDF-1 alpha is crucial in neoangiogenesis and in the mobilization and homing of endothelial progenitor cells to the ischemic coronary vessels. Numerous studies indicate that circulating sex hormones are ...
Jiang Xuecheng - - 2012
The development of an indirect competitive immunomagnetic-proximity ligation assay (ICIPLA), which is a novel method for detecting small molecules, is described in this report. Free small molecules in samples can be detected using a proximity ligation assay (PLA); the detection is based on the proximity effect caused by a high ...
Omana-Zapata I - - 2012
INTRODUCTION: Hematopoietic stem cell transplantation, which requires accurate enumeration of stem cells, is routinely used in clinical settings. Flow cytometry provides a qualitative and quantitative assessment of CD34(+) cells. Precision, linearity, and stability of the novel BD™ Stem Cell Enumeration (SCE) Kit were evaluated on two flow cytometry platforms using ...
Smetana Volodymyr - - 2012
Golden opportunity: Na(13) Au(12) Ga(15) is the first Na-containing, thermodynamically stable quasicrystal and was discovered during systematic exploration of the polar intermetallic Na-Au-Ga system. Its electron-to-atom ratio, 1.75, is extremely low for Bergman-type icosahedral phases, but it is the substantial Au content that allows Hume-Rothery stabilization and promotes novel Na-Au ...
Lau Ching-Ching - - 2012
Mushrooms are high in protein content, which makes them potentially a good source of antihypertensive peptides. Among the mushrooms tested, protein extracts from Pleurotus cystidiosus (E1Pc and E5Pc) and Agaricus bisporus (E1Ab and E3Ab) had high levels of antihypertensive activity. The protein extracts were fractionated by reverse-phase high performance liquid ...
Wong Ying-Chieh - - 2012
The radical cascade protocol of the α-cyano α-TMS/aryl-capped alkynyl aryl ketones promoted by tert-butyl hydroperoxide under catalysis with tetrabutylammonium iodide in refluxing benzene has been developed, leading to the construction of a variety of highly functionalized [6,6,5] tricyclic frameworks in an efficient manner.
Serrano-Pérez Juan J - - 2012
The photocycloaddition reaction of benzene with ethylene has been studied at the CASSCF level, including the characterization of an extended conical intersection seam. We show that the chemical selectivity is, in part, controlled by this extended conical intersection seam and that the shape of the conical intersection seam can be ...
Zins Emilie-Laure - - 2012
Reactions between dilute methane and non-energetic hydroxyl radicals were carried out at 3.5 K. The temperature was kept low in order to characterize the step-wise reaction and prevent parasitic side reactions. The hydroxyl radicals originate from discharged H2O/He mixtures. The reactions were monitored in-situ using a Fourier transform infrared spectrometer. ...
Strong Vivian E VE Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY, - - 2013
Disease-specific survival (DSS) for GC patients differs in Eastern and Western countries. The aim is to compare outcomes of US and Korean patients following resection of early-stage, node-negative gastric carcinoma (GC). All patients (1995-2005) with T1N0 gastric carcinoma, excluding gastroesophageal tumors, were evaluated. DSS was compared by adjusting for prognostic ...
Kale Akshay - - 2012
Insulator-based dielectrophoresis (iDEP) has been established as a powerful tool for manipulating particles in microfluidic devices. However, Joule heating may become an issue in iDEPmicrodevices due to the local amplification of electric field around the insulators.This results in an electrothermal force that can manifest itself in the flow field in ...
Gyanda Reena - - 2012
α-Conotoxins are peptide neurotoxins that selectively inhibit various subtypes of nicotinic acetylcholine receptors. They are important research tools for studying numerous pharmacological disorders, with profound potential for developing drug leads for treating pain, tobacco addiction, and other conditions. They are characterized by the presence of two disulfide bonds connected in ...
Miao Zhen - - 2012
We extend the existing literature on food taxes targeting obesity. We systematically incorporate the implicit substitution between added sugars and solid fats into a comprehensive food demand system and evaluate the effect of taxes on sugars and fats. The approach conditions how food and obesity taxes affect total calorie intake. ...
Dong Chun-Hai - - 2012
The plant actin depolymerizing factor (ADF) binds to both monomeric and filamentous actin, and is directly involved in the depolymerization of actin filaments. In vivo actin filament turnover plays an important role in the control of multicellular activities in various types of plant cells. To better understand the actin binding ...
Sepil Irem - - 2012
Major histocompatibility complex (Mhc) genes are frequently used as a model for adaptive genetic diversity. Although associations between Mhc and disease resistance are frequently documented, little is known about the fitness consequences of Mhc variation in wild populations. Further, most work to date has involved testing associations between Mhc genotypes ...
Meyer Steffen - - 2012
Bioinspired organometallic chemistry: An oxoiron(IV) unit has been trapped within a macrocyclic tetracarbene ligand, merging a key bioinorganic intermediate with a popular organometallic scaffold. The stability of the new complex has allowed its characterization by a variety of methods, which show a strong σ-donating tetracarbene coordination leading to an S=1 ...
Dedieu Nathalie N Pediatric Cardiology, Cardiothoracic Unit, Great Ormond Street Hospital, London, UK. - - 2013
Barth syndrome is an X-linked recessive disorder that is characterized by cardiomyopathy, variable neutropenia, skeletal myopathy, growth delay, and organic aciduria. The cardiac involvement typically results in a high risk of severe heart failure in infancy or early childhood. While Berlin Heart EXCOR is widely accepted as ventricular assistance in ...
Jin Mingjie - - 2012
High productivity processes are critical for commercial production of cellulosic ethanol. One high productivity process - continuous hydrolysis and fermentation - has been applied in corn ethanol industry. However, little research related to this process has been conducted on cellulosic ethanol production. Here we report and compare the kinetics of ...
Karipcin Fethiye Sinem - - 2012
There are limited data on the use of steroids and antibiotics in assisted reproductive technology (ART). Our aim was to evaluate the impact of these treatments on the outcome of IVF cycles in which Assisted Hatching (AH) was performed. We studied a retrospective cohort in a large university-affiliated infertility centre. ...
Ter Schure Janna M A - - 2012
INTRODUCTION:: Dientamoeba fragilis infection in children is common, and its incidence has increased since the introduction of more sensitive molecular techniques. There is no consensus on the optimal treatment. Current medical practice in the Netherlands is to treat symptomatic children with clioquinol or metronidazole. This study attempts to obtain more ...
Kato Tatsuya - - 2012
BACKGROUND: The cutoff value of preoperative serum carcinoembryonic antigen (CEA) levels has not been investigated using appropriate subgroup analyses for non-small cell lung carcinoma (NSCLC). This study was undertaken to determine whether the most predictive preoperative CEA level for risk of recurrence differs according to histological type, and how smoking ...
Zou Xiaoxin - - 2012
A porous TiO(2)-Ag core-shell nanocomposite material with a large surface area was synthesized by in situ hydrolyzation of Sn(2+)-grafted titanium glycolate microspheres in the presence of Ag(+) ions. The as-prepared nanocomposite material was shown to serve as an efficient self-cleaning surface-enhanced Raman scattering (SERS) substrate.
Dai Bingbing B Department of Neurosurgery, The University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Blvd., Houston, TX 77030, - - 2013
The forkhead box M1 (FoxM1) is a key transcription factor regulating multiple aspects of cell biology. Prior studies have shown that FoxM1 is overexpressed in a variety of human tumors, including brain tumor, and plays a critical role in cancer development and progression. In this study we found that FoxM1 ...
Vilasi A - - 2012
A range of debilitating human diseases is known to be associated with the formation of stable highly organized protein aggregates known as amyloid fibrils. The early prefibrillar aggregates behave as cytotoxic agents and their toxicity appears to result from an intrinsic ability to impair fundamental cellular processes by interacting with ...
Abela Andrew R AR Department of Psychology, McGill University, Montreal, QC, - - 2013
In this study, we examined how risk and delay influence rats' decision-making, and the role of the ventral hippocampus (VHC) and orbitofrontal cortex (OFC) in the valuation of these two factors. We used a touchscreen testing method in which rats with VHC lesions, OFC lesions and sham control surgery made ...
Choudhary Abha A Department of Pediatrics, Weill Cornell Medical College, New York Presbyterian Hospital, New York, New York, - - 2013
Data on 25-hydroxyvitamin D (25-OH D) status among survivors of childhood cancer are limited. Our aim was to determine the prevalence of and risk factors for 25-OH D insufficiency in a large, diverse population of cancer survivors being followed in a childhood cancer survivor clinic. Retrospective chart review in survivors ...
Wassermann Louise - - 2012
The ATP-binding cassette subfamily G member 2 (ABCG2) transporter is a member of the ATP-binding cassette (ABC) family of efflux carriers that mediates cellular extrusion of various drugs and toxins. In the mammary gland, ABCG2 is expressed at the apical membrane of alveolar epithelial cells and is induced during lactation. ...
Gottliebsen Martin - - 2012
The tension band plating technique for hemiepiphysiodesis is new and advocated because it is believed to reduce the risk of premature closure of the growth plate compared to stapling. The benefit of the tension band plating technique has not yet been proven in experimental or randomized clinical studies. Ten weeks ...
Formenti Silmara - - 2012
Aldosterone acting on the brain stimulates sodium appetite and sympathetic activity by mechanisms that are still not completely clear. In the present study, we investigated the effects of chronic infusion of aldosterone and acute injection of the mineralocorticoid receptor antagonist RU 28318 into the fourth ventricle (4th V) on sodium ...
Santoro Angela - - 2012
Aim of this work is to provide a detailed comparison of clinical-pathologic features between well differentiated and poorly differentiated tumors according to their BRAF and RASSF1A status.We analyzed RASSF1A methylation by MSP and BRAF mutation by LCRT-PCR with LightMix® kit BRAF V600E in neoplastic thyroid tissues. Immunohistochemical evaluation of RASSF1A ...
Wu Yiman - - 2012
For mass spectrometry (MS)-based metabolomics, it is important to use the same amount of starting materials from each sample to compare the metabolome changes in two or more comparative samples. Unfortunately, for biological samples, the total amount or concentration of metabolites is difficult to determine. In this work, we report ...
Caudwell Phillipa - - 2012
BACKGROUND: There are strong logical reasons why energy expended in metabolism should influence the energy acquired in food-intake behavior. However, the relation has never been established, and it is not known why certain people experience hunger in the presence of large amounts of body energy. OBJECTIVE: We investigated the effect ...
Heininger Ulrich - - 2012
Pandemic influenza A/H1N1 (piA) caused significant morbidity and mortality worldwide. We compared characteristics of piA (2009/10) to those of seasonal influenza A (siA; 2007/08/09) in 134 (piA/siA: N=55/79) hospitalized patients <18 years of age. Chronic disease was present in 25%/33%. Most common symptoms were fever (87%/94%), cough (78%/86%), rhinitis (76%/76%) ...
Zakeri Issa F IF Department of Epidemiology and Biostatistics, Drexel University, Philadelphia, PA, - - 2013
Prediction equations of energy expenditure (EE) using accelerometers and miniaturized heart rate (HR) monitors have been developed in older children and adults but not in preschool-aged children. Because the relationships between accelerometer counts (ACs), HR, and EE are confounded by growth and maturation, age-specific EE prediction equations are required. We ...
Rosenthal Dorothy L - - 2012
BACKGROUND: The most important indicator for urologic surgeons at The Johns Hopkins Hospital to have a patient undergo cystoscopy is a cytologic diagnosis of high-grade urothelial carcinoma. The template was designed to standardize diagnostic categories so clinicians can manage their patients uniformly. The template was based in part on the ...
Guo Caixia - - 2012
Aims:  This study aims to assess the removal mechanism of patulin using heat-treated Saccharomyces cerevisiae cells and identify the role of different cell wall components in the binding process. Methods and Results:  In order to understand the binding mechanism, viable cells, heat-treated cells, cell wall and intracellular extract were performed ...
Coffman Lan L Department of Internal Medicine, Division of Hematology Oncology, University of Michigan, Ann Arbor, MI, - - 2013
The endothelin receptor-A (ETRA) plays an important role in tumor cell migration, metastasis, and proliferation. The endothelin receptor B (ETRB) plays a critical role in angiogenesis and the inhibition of anti-tumor immune cell recruitment. Thus dual blockade of ETRA and ETRB could have significant anti-tumor effects. Dual ETRA/ETRB blockade with ...
Yagi Haruyo - - 2012
Human mesenchymal stem cells (hMSCs) are considered a highly promising candidate cell type for cell-based tissue engineering and regeneration because of their self-renewal and multi-lineage differentiation characteristics. Increased levels of reactive oxygen /nitrogen species (ROS/ RNS) are associated with tissue injury and inflammation, impact a number of cellular processes, including ...
Vanhatalo Jarno P - - 2012
Many countries define legislative targets for the ecological status of aquatic ecosystems. Fulfilling these legally binding targets requires often large scale and expensive management actions. The expected benefits from alternative actions are commonly compared with deterministic ecosystem models. However, from a practical management point of view the uncertainty in model ...
Loayza-Muro Raul Augusto - - 2012
In high altitude Andean streams an intense solar radiation and coinciding metal pollution allow the persistence of only a few specialized taxa, including chironomids. The aim of the present study was therefore to determine the mechanisms underlying the persistence of chironomids under these multiple stress conditions, hypothesizing that melanin counteracts ...
Li Jingjing J Departments of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, - - 2013
Although long-chain ω-3 (n-3) PUFAs (LCω3PUFAs) have been linked to the prevention of some inflammatory disorders, little is known about the association between these fatty acids and incidence of asthma. The objective was to prospectively investigate the association between LCω3PUFAs and fish intake and incidence of asthma among American young ...
Xu Jie J Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama 35294, - - 2013
GH and prolactin (PRL) are structurally related hormones that exert important effects in disparate target tissues. Their receptors (GHR and PRLR) reside in the cytokine receptor superfamily and share signaling pathways. In humans, GH binds both GHR and PRLR, whereas PRL binds only PRLR. Both hormones and their receptors may ...
Klapötke Thomas Matthias - - 2012
This unique study reports on the 1,3-bis(nitroimide)-1,2,3-triazolate anion. This compound provides unique insight into both academic and practical considerations surrounding high-nitrogen systems. The bonding in this energetic anion can be represented multiple ways, one of which includes a chain of alternating positive negative charges nine atoms long. The validity of ...
Klink Joseph C JC Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH, - - 2013
Resveratrol increases lifespan and decreases the risk of many cancers. We hypothesized resveratrol will slow the growth of human prostate cancer xenografts. SCID mice were fed Western diet (40% fat, 44% carbohydrate, 16% protein by kcal). One week later, human prostate cancer cells, either LAPC-4 (151 mice) or LNCaP (94 ...
Zhou M - - 2013
The interleukin-10 (IL-10) gene polymorphism (-1082A/G) has been shown to be associated with systemic lupus erythematosus (SLE), but ļ¬ndings are not consistent across studies. The aim of our meta-analysis was to assess the association between the -1082A/G polymorphism in the IL-10 gene and SLE. We searched all publications on the ...
Kumada Takashi - - 2012
BACKGROUND AND AIM: The average age of hepatitis C virus (HCV)-related hepatocellular carcinoma (HCC) patients has been rising in Japan. We evaluate characteristics of HCV-positive patients who develop HCC in older age to determine an optimal surveillance strategy. METHODS: A total of 323 patients with 3 or more years of ...
Morris Carolyn Louise CL Department of Geriatrics, University of Michigan, Ann Arbor, MI, USA. - - 2013
To evaluate cognitive processing in elderly women with urge incontinence as compared to continent cohorts by measuring performance on neuropsychological tests of working memory, attention and inhibition. To measure speed of information processing, intensity of bladder filling sensation, and urine volume at a first desire (FDV) and strong desire to ...
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