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Results 451 - 500 of 2475
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Hong Wei - - 2012
We report two new low band-gap conjugated polymers containing dipyrrolo[2,3-b:2',3'-e]pyrazine-2,6(1H,5H)-dione (PzDP), PPzDPDP-BT and PPzDPDP-TT, both showing ambipolar transport in organic thin film transistors (OTFTs), with hole mobility up to 0.066 cm(2) V(-1) s(-1), electron mobility up to 0.021 cm(2) V(-1) s(-1), and high current on-to-off ratios of 10(5)-10(6).
Qu Yongquan - - 2012
There is increasing interest in developing artificial systems that can mimic natural photosynthesis to directly harvest and convert solar energy into usable or storable energy resources. Photocatalysis, in which solar photons are used to drive redox reactions to produce chemical fuel, is the central process to achieve this goal. Despite ...
D'Ambrosio Lia - - 2012
To the Editor: The study by Gler et al. (June 7 issue)(1) provides a needed reminder regarding the development pipeline for drugs for tuberculosis and multidrug-resistant (MDR) tuberculosis.(2) Delamanid with bedaquiline is increasing the potential for improving current regimens for tuberculosis. In their editorial in the same issue, Chaisson and ...
Afzal Shoaib - - 2012
Sun exposure is a major risk factor for skin cancer and is also an important source of vitamin D. We tested the hypothesis that elevated plasma 25-hydroxyvitamin D (25-OH-vitD) associates with increased risk of non-melanoma and melanoma skin cancer in the general population. We measured plasma 25-OH-vitD in 10,060 white ...
Yager Janice W - - 2012
Gene expression changes in primary human uroepithelial cells exposed to arsenite and its methylated metabolites were evaluated to identify cell signaling pathway perturbations potentially associated with bladder carcinogenicity. Cells were treated with mixtures of inorganic arsenic and its pentavalent or trivalent metabolites for 24 hr at total arsenic concentrations ranging ...
Niesten Joris M - - 2012
OBJECTIVES: To evaluate the accuracy and reproducibility of CT-perfusion (CTP) by finding the optimal artery for the arterial input function (AIF) and re-evaluating the necessity of the venous output function (VOF). METHODS: Forty-four acute ischaemic stroke patients who underwent non-enhanced CT, CTP and CT-angiography using 256-slice multidetector computed tomography (MDCT) ...
Ziuzina D - - 2012
AIMS: The main objective of this study was to determine the inactivation efficacy of dielectric barrier discharge atmospheric cold plasma (DBD-ACP) generated inside a sealed package for Escherichia coli ATCC 25922. METHODS AND RESULTS: A plasma discharge was generated between two circular aluminium electrodes at 40 kV. E. coli suspensions ...
Ambrožič Avguštin Jerneja - - 2012
A bacterial strain designated JA-1, related to Janthinobacterium lividum, was isolated from glacier ice samples from the island Spitsbergen in the Arctic. The strain was tested for phenotypic traits and the most prominent appeared to be the dark red brown to black pigmentation different from the violet pigment of Janthinobacterium, ...
Mohos Gabor - - 2012
Abstract Defects of the skin and underlying soft tissue of the neck are uncommon, and the surgeon's main objective is to achieve reliable long-term coverage of the exposed vital organs with well-vascularised tissue harvested from a distant donor site. We present a patient whose extended irradiation site together with the ...
Deniz D A - - 2012
Complete dentures should satisfy patients' needs for comfort, function and aesthetics. Thirty edentulous patients were enrolled in this study. Two sets of complete dentures were made for each patient: one with bilaterally balanced occlusion and the other with lingualised occlusion. The patients used each type of denture for 6 months. A ...
Yang Xiao - - 2012
Activation-associated secreted protein (ASP) had been found in many helminthes, which was associated with pathogenesis and stage transition. A complementary DNA (cDNA) sequence encoding a putative two-domain ASP was obtained from an Angiostrongylus cantonensis fourth-stage larvae cDNA library, which we designated as AgASP. The cDNA of AgASP contains an open ...
Victoroff Michael S MS Department of Family Medicine, University of Colorado School of Medicine, 5195 E. Weaver Dr., Centennial, CO 80121-3500, USA. - - 2013
Electronic health records (EHRs) might reduce medical liability claims and potentially justify premium credits from liability insurers, but the evidence is limited. To evaluate the association between EHR use and medical liability claims in a population of office-based physicians, including claims that could potentially be directly prevented by features available ...
- - 2012
Many palaeoclimate studies have quantified pre-anthropogenic climate change to calculate climate sensitivity (equilibrium temperature change in response to radiative forcing change), but a lack of consistent methodologies produces a wide range of estimates and hinders comparability of results. Here we present a stricter approach, to improve intercomparison of palaeoclimate sensitivity ...
Di Napoli Claudia - - 2012
We have investigated the ability of dual-frequency Coherent Antistokes Raman Scattering (D-CARS) micro-spectroscopy, based on femtosecond pulses (100 fs or 5 fs) spectrally focussed by glass dispersion, to distinguish the chemical composition of micron-sized lipid droplets consisting of different triglycerides types (poly-unsaturated glyceryl trilinolenate, mono-unsaturated glyceryl trioleate and saturated glyceryl ...
Tveiten O V - - 2012
OBJECTIVES: There are limited data on treatment effect in early and drug-naïve Parkinson's disease (PD) outside of clinical trials. We sought to review the treatment effects on motor symptoms in early, unselected PD patients. METHODS: We included 183 drug-naïve patients from a longitudinal cohort (The Norwegian ParkWest study). At the ...
Wang Hailin - - 2012
A facile and universal approach is reported for the preparation of silica particles of various mesostructures based on the self-assembly of amphiphilic precursor polymers in water and subsequent condensation. Depending on the hydrophilization degree of hyperbranched polyethoxysiloxane, various silica morphologies including mesoporous particles, hollow nanospheres and ultrasmall particles with high ...
Donmez-Altuntas Hamiyet - - 2012
Patulin (PAT) is a fungal secondary metabolite commonly present in apples and apple products. In the present study, PAT was evaluated for its genotoxic, cytotoxic and cytostatic effects to human peripheral blood lymphocytes by using the cytokinesis-block micronucleus cytome (CBMN Cyt) assay. Lymphocyte cultures were treated with PAT at the ...
Yang Lian-He - - 2013
Axin is an important negative regulator of Wnt pathway. We have reported that reduced expression of Axin could be detected in lung cancer tissues, but the mechanism is not clear. By analyzing the genomic sequence, we note that Axin gene promoter is rich in CpGs. Little is known about the ...
Yousef George M GM Joan C. Edwards School of Medicine, Marshall University, 1249 15th St, Huntington, WV 25701, - - 2013
A 64-year-old woman presented with a hemorrhagic perifollicular rash on her legs while taking warfarin. After biopsy, vitamin C deficiency was suggested as the diagnosis, which ascorbic acid assays later confirmed. Clinical resolution of the rash followed supplementation with vitamin C. Patients on a vitamin K limited diet may also ...
O'Neill Hugh St C - - 2012
The magmatic layers of the oceanic crust are created at constructive plate margins by partial melting of the mantle as it wells up. The chemistry of ocean floor basalts, the most accessible product of this magmatism, is studied for the insights it yields into the compositional heterogeneity of the mantle ...
Miyake Takahito M TM Department of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, 1155 Herman Pressler, Unit 1362, Houston, TX 77030, - - 2013
Ovarian cancer remains the most lethal gynecologic malignancy. Although standard platinum-based chemotherapy results in high response rates, more than 70% of patients with advanced disease will experience recurrence within 5 years. Therefore, novel treatment strategies to increase primary efficacy, decrease recurrence after primary treatment and improve the response rate for ...
Lautenbach Anne - - 2012
OBJECTIVE: To report the case of a morbidly obese 49-year-old woman with nonspecific interstitial pneumonia who underwent bariatric surgery. Because of inadequate weight loss after sleeve gastrectomy, duodenal switch as component of a stepwise treatment was performed and led to unexplained progressive weight loss and malnutrition. METHOD: Case report. RESULTS: ...
Rademaker Marius - - 2012
Facial involvement of atopic eczema in young children can be difficult to manage. Chronic scratching and rubbing, combined with parental reluctance to use topical corticosteroids on the face, often results in recalcitrant facial eczema. While wet wraps are a useful management option for moderate/severe atopic eczema involving the trunk and ...
Xu Jianling - - 2012
Evaluation of the efficiency of aircraft liquid waste treatment has previously been conducted to prevent pollution of the environment. The current study aimed to provide a set of practical methods for efficient airport sanitary supervision. Aircraft liquid waste was collected at Longjia International Airport, Changchun from multiple flights. The efficiency ...
Tyra M - - 2012
The objective of the present study was to analyze the level of intramuscular fat (IMF) in loin (musculus longissimus dorsi) and ham (musculus semimembranosus) and the level of subcutaneous fat in these cuts depending on breed, age and the expression level of FABP3 and LEPR genes. The results obtained showed ...
Wang Feng - - 2012
A novel and efficient copper-catalyzed Michael addition of acrylic derivatives with primary alcohols in the presence of base has been developed. The protocol uses readily available acrylic derivatives and primary alcohols as the starting materials, inexpensive CuCl(2) as the catalyst, and the corresponding addition products were obtained in moderate to ...
Timæus Ian M - - 2012
Summary This paper investigates the impact on birth intervals of three distinct birth control strategies: stopping childbearing, spacing births and the postponement of further childbearing for reasons unrelated to women's family-building histories. A macro-simulation model of the family-building process is described that incorporates heterogeneity in fecundability. This model is used ...
Cohen D A - - 2012
BACKGROUND: Enteral nutrition formulas enriched with eicosapentaenoic acid (EPA) and gamma-linolenic acid (GLA) may modulate inflammatory processes and improve outcomes in mechanically-ventilated patients with respiratory failure. The present study aimed to determine whether there were differences in nutritional indices (protein intake, energy intake, fat intake) and outcomes [days on mechanical ...
Elens Laure - - 2012
Every month, new releases on the relationship between pharmacogenetic biomarkers and immunosuppressive drug therapy in kidney transplantation are published. However, the systematic clinical application of these discoveries occurs at a very slow pace, and the usefulness of knowing a patient's genotype remains an important matter of debate. This can be ...
Heinbokel Timm - - 2012
Aging affects all compartments of the immune response and has a major impact on transplant outcome and organ quality. Although clinical trials in the aging transplant population remain rare, our current understanding of immunosenescence provides a basis for an age-adapted immunosuppression and organ allocation with the goal to optimize utilization ...
García-Blázquez V - - 2013
To assess the diagnostic accuracy of computed tomography (CT) angiography in the evaluation of patients with an episode of acute gastrointestinal haemorrhage. Systematic review and meta-analysis to estimate pooled accuracy indices. A bivariate random effects model was adjusted to obtain a summary receiver-operating characteristic (sROC) curve and the corresponding area ...
Louhichi Nacim - - 2012
Lamellar ichthyosis (LI, MIM# 242300) is a severe autosomal recessive genodermatosis present at birth in the form of collodion membrane covering the neonate. Mutations in the TGM1 gene encoding transglutaminase-1 are a major cause of LI. In this study molecular analysis of two LI Tunisian patients revealed a common nonsense ...
Rusu Mugurel Constantin - - 2012
This study aimed to evaluate by immunohistochemistry and transmission electron microscopy (TEM) the morphological features of the oral mucosa endothelial tip cells (ETCs) and to determine the immune and ultrastructural patterns of the stromal nonimmune cells which could influence healing processes. Immune labeling was performed on bioptic samples obtained from ...
Du Zhiyong - - 2012
Mesenchymal stem cell (MSC) therapy can prevent hepatic parenchymal cell loss and promote tissue repair. However, poor MSC engraftment is one of the primary barriers to the effectiveness of cell therapy. This is because culture-expanded MSCs progressively downregulate CXCR4 expression and lose their ability to migrate toward a gradient of ...
Chellamuthu Vasuki Ranjani - - 2012
This article reviews the current state-of-the-art concerning the functions of the signal processing protein PII in cyanobacteria and plants, with a special focus on evolutionary aspects. We start out with a general introduction to PII proteins, their distribution, and their evolution. We also discuss PII-like proteins and domains, in particular, ...
Vanhercke Thomas - - 2012
Society has come to rely heavily on mineral oil for both energy and petrochemical needs. Plant lipids are uniquely suited to serve as a renewable source of high-value fatty acids for use as chemical feedstocks and as a substitute for current petrochemicals. Despite the broad variety of acyl structures encountered ...
Stratford Thomas R TR Laboratory of Integrative Neuroscience, Department of Psychology (m/c 285), University of Illinois at Chicago, Chicago, IL, USA. - - 2013
Intense feeding can be elicited by injections of the GABA(A) receptor antagonist bicuculline into the medial ventral pallidum (VPm), a basal forebrain structure anatomically interposed between two other feeding-related brain regions, the nucleus accumbens shell and the lateral hypothalamus (LH). To determine whether the VPm effects changes in feeding behavior ...
Peters Tobias - - 2012
BACKGROUND: Participation in first human applications of retinal neuroprosthesis may create psychological stress for blind retinitis pigmentosa patients. The aim of this study was to assess the emotional wellbeing of patients undergoing implantation of a subretinal implant. METHODS: Nine blind patients participating in a pilot trial with subretinal implants were ...
Zhang Zaichao - - 2012
SigmaB factor is an important regulatory factor for stress response in Gram-positive bacteria such as Listeria monocytogenes (L. monocytogenes), Staphylococcus aureus and Bacillus subtilis. However, the activity of SigmaB factor is regulated by RsbV factor. Currently, the functional studies of RsbV factor are mostly focused on non-pathogenic B. subtilis, but ...
Liu Xiao-Fei - - 2012
Manganese (Mn) is an essential element required for normal development and reproduction. However, little is known about the reproductive toxicity of Mn in birds. To investigate the Mn-induced toxicity on testicular trace element levels and crucial hormonal parameters on male reproduction in birds, 50-day-old male Hyline cocks were fed either ...
Paul Elisabeth - - 2012
The international community holds high expectations for aid producing demonstrable results in the health sector, at the global and developing country levels. Yet, measuring the effectiveness of aid presents methodological challenges. Existing evaluation frameworks are not sufficiently geared toward learning whether and how practices have changed. We present a framework ...
Iwahashi Shuichi - - 2012
PURPOSE: Cholangiolocellular carcinoma (CLC) is an extremely rare malignant liver tumor. It is thought to originate from the ductules and/or canals of Hering, where hepatic stem cells (HpSC) are located, but there are few reports on cancer stem cell markers in CLC. Thus, we evaluated the significance of cancer stem ...
Kreyenschulte Dirk - - 2012
Over the past decades a large amount of biopolymers originating from various types of microorganisms have been reported. With ongoing research the number of possible applications has increased rapidly, ranging from use as food additives and biomedical agents to biodegradable plastics from renewable resources. In spite of the plethora of ...
Schraermeyer Ulrich - - 2012
Objective: Due to its low price, bevacizumab, which binds vascular endothelial growth factor, is currently used off-label for the treatment of over 50 different eye diseases and has been adopted worldwide despite the absence of serious preclinical data. This study examines the effects of intravitreal bevacizumab on monkey eyes with ...
Sapsford Ruth R - - 2012
PURPOSE: Urethral pressure increases during voluntary pelvic floor (PF) muscle contractions in healthy women. As PF and abdominal muscle activity is coordinated, this study aimed to determine whether specific abdominal muscle actions also change urethral pressure. METHODS: Urethral pressures were measured in seven healthy women during lower abdominal in-drawing, abdominal ...
Ozyıldız Figen - - 2012
In recent years, functional fabrics possessing antimicrobial activity have drawn significant interest because antibiotic resistance is becoming widespread among pathogenic microorganisms. The aim of this study was to produce microcapsules incorporating ozonated red pepper seed oil with antimicrobial properties and apply them to nonwoven fabrics to prepare functional textiles. Red ...
Tao Hai-Quan - - 2012
It is well known that puerarin attenuates ischemia-reperfusion injury and promotes function recovery of ischemic region. However, due to its reverse physiochemical properties, puerarin does not easily cross the blood-brain barrier. The aim of the present study is to create puerarin nanoparticles which increase and prolong the puerarin concentration in ...
Szpinda Michał - - 2012
PURPOSE: Knowledge on the normative growth of the spine is relevant in the prenatal detection of its abnormalities. This study describes the size of the ossification center of C1-S5 vertebral bodies. MATERIALS AND METHODS: Using CT, digital-image analysis, and statistics, the size of the ossification center of C1-S5 vertebral bodies ...
Goethals Sabine - - 2012
In their practice, nurses make daily decisions that are ethically informed. An ethical decision is the result of a complex reasoning process based on knowledge and experience and driven by ethical values. Especially in acute elderly care and more specifically decisions concerning the use of physical restraint require a thoughtful ...
Adams James B - - 2012
This study investigates both the level of toxic metals in children with autism and the possible association of those toxic metals with autism severity. This study involved 55 children with autism ages 5-16 years compared to 44 controls with similar age and gender. The study included measurements of toxic metals in ...
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