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Results 301 - 350 of 2827
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Mérie Charlotte C Department of Cardiology, Copenhagen University Hospital Gentofte, Niels Andersens Vej 65, 2900 Hellerup, Denmark. - - 2012
The need for anticoagulation after surgical aortic valve replacement (AVR) with biological prostheses is not well examined. To perform a nationwide study of the association of warfarin treatment with the risk of thromboembolic complications, bleeding incidents, and cardiovascular deaths after bioprosthetic AVR surgery. Through a search in the Danish National ...
Rebholz C M - - 2012
Background/objectives:Cardiovascular disease (CVD) is the leading cause of death in the United States and the world. Clinical trials have suggested that soybean protein lowers lipids and blood pressure. The effect of soybean protein on novel CVD risk factors has not been well studied. The objective of this study was to ...
Li Yue-Sheng - - 2012
We have successfully synthesized S = 1/2 kagome antiferromagnets MCu(3)(OH)(6)Cl(2) (M = Ni and Co) by a hydrothermal method with a rotating pressure vessel. Structural characterization shows that both compounds have similar crystal structure to ZnCu(3)(OH)(6)Cl(2) with [Formula: see text] symmetry. As with ZnCu(3)(OH)(6)Cl(2), the compounds show no obvious hysteresis at 2 K. ...
van Beijsterveldt Catharina E M - - 2012
The Netherlands Twin Register (NTR) began in 1987 with data collection in twins and their families, including families with newborn twins and triplets. Twenty-five years later, the NTR has collected at least one survey for 70,784 children, born after 1985. For the majority of twins, longitudinal data collection has been ...
Aluotto Sabrina - - 2012
Platensimycin and platencin are compounds that were discovered at Merck Research Laboratories and have shown promising antibacterial activity. They are both produced in fermentation by the actinomycete Streptomyces platensis. Merck reported a crude, insoluble production medium to produce the antibiotics. To test the possible effects of different primary metabolites and ...
Morigaki Atsunori - - 2012
Treatment of β-fluoroalkylated-α,β-unsaturated ketones with 1.2 equiv. of various arylboronic acids in the presence of 5 mol% of [Rh(COD)(2)]BF(4) and 6 mol% of (S)-BINAP in toluene/H(2)O (v/v = 4/1) at the reflux temperature for 3 h gave the corresponding Michael adducts in high yields with over 90% enantioselectivity. Though other ...
Zhou Li - - 2012
BACKGROUND: Plasminogen activator inhibitor (PAI)-2 was previously shown to be less frequently expressed in hepatocellular carcinoma (HCC). The present study was designed to investigate the clinical, pathological, and prognostic significance of PAI-2 expression in HCC. METHODS: Expression of PAI-2 was detected immunohistochemically for specimens from 78 patients with HCC after ...
Hauschild Oliver - - 2012
PURPOSE: The aim of the present study was to assess the changes in rotational alignment introduced by total knee arthroplasty (TKA) and the reproducibility of pre- and postoperative CT measurements of rotational limb alignment. METHODS: For this purpose we analyzed data from 196 consecutive cruciate-retaining, fixed bearing Columbus TKA procedures. ...
Ezechi Oliver C - - 2012
Abstract Objective: There are conflicting report on the association of HIV infection and asymptomatic bacteriuria (ASB). Most of these studies were from areas with low HIV burden. This study determined the prevalence and risk factors of ASB in HIV positive pregnant women. Methods: A cross sectional study among HIV positive ...
Kleindienst Andrea - - 2012
BACKGROUND: The hormone and neuropeptide arginine-vasopressin is designated to the maintenance of osmotic homoeostasis and blood pressure regulation. While experimental data show vasopressin V(1A) receptors to regulate aquaporin (AQP)4 water channel dependent brain water movement, the specific role in vasogenic and cytotoxic edema formation remains unclear. The present study was ...
Breed M F - - 2012
Habitat fragmentation has been shown to disrupt ecosystem processes such as plant-pollinator mutualisms. Consequently, mating patterns in remnant tree populations are expected to shift towards increased inbreeding and reduced pollen diversity, with fitness consequences for future generations. However, mating patterns and phenotypic assessments of open-pollinated progeny have rarely been combined ...
Chang Pei-Hung - - 2012
Unexpected fatal events in patients with head and neck cancers undergoing concurrent chemoradiation therapy are a clinical concern. Malnutrition, which is reported frequently in head and neck cancer patients, are associated with immunity derangement. The purpose of this study was to identify risk factors for early death of patients undergoing ...
Pulkkinen Pasi - - 2012
BACKGROUND: Assessment of osteoporotic fracture risk is based primarily on bone mineral density (BMD) measurements using dual X-ray absorptiometry (DXA). METHODS: However, recent evidence indicates that the method is insufficient for accurate individual risk assessment; in addition to methodological inaccuracies related to DXA, the mechanical strength of bone is influenced ...
Holland E Penelope - - 2012
Patterns of herbivore browse at small scales, such as the rate of leaf consumption or plant preferences, drive the impact of herbivores on whole-plant processes, such as growth or survival, and subsequent changes in plant population structure. However, herbivore impacts are often non-linear, highly variable and context-dependent. Understanding the effect ...
Gaunt Tom R TR MRC Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Oakfield Grove, Bristol, UK. - - 2013
Activated partial thromboplastin time (aPTT) is an important routine measure of intrinsic blood coagulation. Addition of activated protein C (APC) to the aPTT test to produce a ratio, provides one measure of APC resistance. The associations of some genetic mutations (eg, factor V Leiden) with these measures are established, but ...
Allemann Pierre - - 2012
BACKGROUND: The purpose of the present study was to analyze long-term survival and disease-free survival after liver resection for giant hepatocellular carcinoma (HCC) ≥ 10 cm compared to HCC < 10 cm in diameter. The surgical approach in the treatment of giant HCC may achieve long-term survival and disease-free survival comparable to treatment of smaller lesions. ...
Hasegawa Tomomi - - 2012
Late mortality following surgical repair of total anomalous pulmonary venous connection (TAPVC) is often associated with pulmonary venous stenosis. We describe here two successful cases of primary sutureless repair for simple TAPVC in patients who had a potential risk of postoperative pulmonary venous stenosis. A 10-day-old neonate with mixed-type TAPVC ...
Endo Jun - - 2012
BACKGROUND: Preoperative traction for hip fractures is of no benefit in semi-urgent surgery. However, its efficacy has not been assessed in cases in which emergency surgery was not possible. We evaluated the efficacy of preoperative skin traction for hip fractures in a level II trauma center in Japan where many ...
Han Yu - - 2012
Substantial evidence has demonstrated that platelet-derived growth factor-D (PDGF-D) is tightly associated with the development and progression of tumors. However, its biological functions in esophageal squamous cell carcinoma (ESCC) remain to be delineated. In this study, we found that expressions of PDGF-D mRNA and protein in ESCC tissues and cells ...
Ullmann Urielle U Center for Medical Genetics UZ Brussel Hospital, Vrije Universiteit Brussel, Brussels, Belgium. - - 2013
Multiple endocrine neoplasia type 1 (MEN1) is an autosomal-dominant cancer syndrome that is caused by a germline mutation in the MEN1 gene encoding a tumour-suppressor protein, menin. MEN1 causes a combination of endocrine tumours such as parathyroid adenomas, pituitary adenomas, glucagonomas, gastrinomas, insulinomas, adrenocortical adenomas and non-endocrine tumours. We here ...
Miller Judith R - - 2012
In an influential paper, Kirkpatrick and Barton (Am Nat 150:1-23 1997) presented a system of diffusive partial differential equations modeling the joint evolution of population density and the mean of a quantitative trait when the trait optimum varies over a continuous spatial domain. We present a stability theorem for steady ...
Shmerling Robert H RH Division of Rheumatology, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA. - - 2012
Gout is an ancient disease. Despite significant advances in the understanding of its risk factors, etiology, pathogenesis, prevention, and treatment, millions of people with gout experience repeated attacks of acute arthritis and other complications. The incidence of gout is increasing, most likely reflecting increasing rates of obesity and other lifestyle ...
Diamanti A - - 2012
Background/Objectives:The practice of home enteral nutrition (HEN) represents a relevant aspect of the clinical management of both malnourished children and well-nourished children unable to be fed using an oral diet. The aim of this study was to estimate in an Italian paediatric population over a 14-year period (1996-2009), the clinical ...
Kurzydłowski Dominik - - 2012
Disodium tetrafluoroargentate(ii) (Na(2)AgF(4)) has been synthesized by the thermal decomposition of NaAg(iii)F(4) in the presence of NaF. This novel synthetic pathway yielded a high-purity product which enabled determination of the crystal structure and magnetic properties of this compound. The crystal structure of Na(2)AgF(4) contains infinite [AgF(2+4/2)](2-) chains, in analogy to ...
Liu Miaomiao - - 2012
To investigate how the microbial community in activated sludge responded to high antibiotic levels, a bench-scale aerobic wastewater treatment system was used to treat oxytetracycline (OTC) mother liquor (OTC-ML). Removal efficiency of chemical oxygen demand decreased from 64.9 to 51.0 % when the OTC level increased from 191.6 to 620.5 mg/L, respectively. ...
Samie Ahmed Abdel - - 2012
Background/Aims: Dual antiplatelet therapy has to be used for at least one month after placement of bare metal coronary stents and for a minimum of one year after placement of drug eluting stents. Because of the higher risk of bleeding, guidelines strongly recommend to delay elective surgery until dual antiplatelet ...
Cho Seungho - - 2012
Gold nanoparticle (Au NP)-mixed metal oxide (MMO) nanocomposite photocatalysts for efficient self-sensitized dye degradations under visible light were prepared by an electrostatically driven self-assembly. Dihydrolipoic acid (DHLA)-capped Au NPs (building block I) were synthesized through a room temperature reaction. Their hydrodynamic size was determined as being around 4.9 nm by ...
Sripreechasak Paranee - - 2012
A novel actinomycete, strain KC-061(T) was isolated from a soil sample collected from Angthong Islands National Park, Surat Thani province, Thailand. Strain KC-061(T) was identified as a member of the genus Nonomuraea through the use of a polyphasic approach. Phylogenetic analyses based on 16S rRNA gene sequencing, strain KC-061(T) belongs ...
Sánchez-Iglesias Ana - - 2012
Hydrophobic interactions constitute one of the most important types of non-specific interactions in biological systems, which emerge when water molecules rearrange as two hydrophobic species come close to each other. Prediction of hydrophobic interactions at the level of nanoparticles (Brownian objects) remains challenging, because of uncontrolled diffusive motion of the ...
Morichika Keisuke - - 2012
Summary The POU family subclass V (POU-V) proteins have important roles in maintaining cells in an undifferentiated state. In Xenopus, expression of the POU-V protein Oct60 was detected in oocytes and was found to decrease in blastula- to gastrula-stage embryos. In addition, Oct60 overexpression inhibits some signals in early embryogenesis, ...
Bertalanič Laura - - 2012
Solvent composition has a large influence on measured antioxidant potential (AOP) of model polyphenols and red wines with 2,2-diphenyl-1-picrylhydrazyl (DPPH). We have shown that incorporation of aqueous buffer in the assay medium results in higher reactivity of catechin and caftaric acid, that are among major polyphenolic constituents of wines. Consequently ...
Berliner Janice L - - 2012
PURPOSE: The purpose of this document is to present a current and comprehensive set of practice recommendations for effective genetic cancer risk assessment, counseling and testing for hereditary breast and ovarian cancer. The intended audience is genetic counselors and other health professionals who care for individuals with, or at increased ...
Schneider Rick - - 2012
BACKGROUND: Intermittent intraoperative neuromonitoring cannot prevent preparative surgical damage or predict imminent recurrent laryngeal nerve (RLN) damage with subsequent development of loss of electromyogram (EMG) signal during thyroid surgery. In case the nerve is stressed, i.e., from traction near the ligament of Berry, the nerve injury is only detected after ...
Watanabe Atsushi - - 2012
Idiopathic pulmonary fibrosis (IPF) is defined as a specific form of chronic, progressive fibrosing interstitial pneumonia of unknown cause. IPF is associated with an increased risk of lung cancer, and lung cancer patients with IPF undergoing pulmonary resection for non-small cell lung cancer have increased postoperative morbidity and mortality. Especially, ...
Yazbek Thierry - - 2012
BACKGROUND: Laparoscopic adjustable gastric banding (LAGB) is one of the most frequently performed bariatric surgeries. Even with a high failure rate, revisional procedures such as re-banding or laparoscopic Roux-en-Y gastric bypass (LRYGB) were commonly performed. Recently, conversions of LAGB to laparoscopic sleeve gastrectomy (LSG) were reported. We will review our ...
Flores-Suárez Luis F - - 2012
Microscopic polyangiitis (MPA) frequently involves the lungs. However, as opposed to granulomatosis with polyangiitis (Wegener's), limited forms are not recognised. In recent years, cases have been reported in which the lungs were affected without other organ manifestations. For years, many have been labelled as idiopathic pulmonary fibrosis (IPF). In this ...
Motiwala S R - - 2012
The current standard treatment of chronic heart failure (HF) is based on clinical judgment, with the goal of achieving the maximally tolerated therapeutic program. The complexity of this approach may contribute to the well-established treatment gaps that exist in HF management; consequently, the risks for morbidity and mortality in this ...
Terpolilli Nicole A NA Department of Neurosurgery, University of Munich Medical Center, Munich, - - 2013
Ischemia, especially pericontusional ischemia, is one of the leading causes of secondary brain damage after traumatic brain injury (TBI). So far efforts to improve cerebral blood flow (CBF) after TBI were not successful because of various reasons. We previously showed that nitric oxide (NO) applied by inhalation after experimental ischemic ...
Koller Heiko H German Scoliosis Center, Werner Wicker Clinic, Im Kreuzfeld 4, 34537 Bad Wildungen, Germany. - - 2013
With progression of cervicothoracic kyphosis (CTK), ankylosing spondylitis (AS) patients suffer functional disability. Surgical correction still poses neurologic risks, while evidence of an ideal technique preventing its complications is weak. We report our results with non-instrumented correction in perspective of a review of literature, serving as an important historical control. ...
Coudrillier Baptiste B Department of Mechanical Engineering, Johns Hopkins University, Baltimore, MD, 21218, USA, - - 2013
This paper presents a computational modeling study of the effects of the collagen fiber structure on the mechanical response of the sclera and the adjacent optic nerve head (ONH). A specimen-specific inverse finite element method was developed to determine the material properties of two human sclera subjected to full-field inflation ...
Shunmugavel Anandakumar A Department of Pediatrics, Medical University of South Carolina, 173 Ashley Avenue, Charleston, SC 29425, - - 2013
Lumbar spinal stenosis (LSS) is the leading cause of morbidity and mortality worldwide. LSS pathology is associated with secondary injury caused by inflammation, oxidative damage and cell death. Apart from laminectomy, pharmacological therapy targeting secondary injury is limited. Statins are FDA-approved cholesterol-lowering drug. They also show pleiotropic anti-inflammatory, antioxidant and ...
Athmaram T N - - 2012
Dengue non-structural protein (NS1) is known to be protective antigen and also has immense application for serodiagnosis. Several serodiagnostic assays available for dengue viral infection are dependent on tissue culture-grown viral proteins. This task is unsafe, laborious, more expensive that makes it unsuitable for routine large-scale production. Although bacterial expression ...
Ovejero Paloma - - 2012
New pyridine-functionalised pyrazole compounds [Hpz(R(n)py)] (R(n) = C(6)H(4)OC(n)H(2n+1); n = 12, 14, 16, 18; ) and their corresponding silver complexes [Ag(Hpz(R(n)py))(2)][A] ([A] = NO(3)(-), BF(4)(-); ) have been synthesised and characterised. All of them, with the exception of , are liquid crystal materials exhibiting monotropic or enantiotropic SmA mesophases, in ...
Sakaguchi Masahiro - - 2012
Two guidelines are currently available to guide Japanese clinicians caring for patients with ventilator-associated pneumonia (VAP): the 2005 American Thoracic Society/Infectious Diseases Society of America (ATS/IDSA) guidelines or the 2008 Japanese Respiratory Society (JRS) guidelines. We aimed to measure compliance with guideline recommendations for VAP in Japanese intensive care units ...
Tao Zhengxu - - 2012
Blue-emitting phosphors of the Ce(3+)-activated phosphosilicate Sr(5)(PO(4))(2)SiO(4) with an apatite structure were prepared via a conventional solid-state reaction method. The X-ray diffraction (XRD), scanning electron microscopy (SEM), photoluminescence (PL) spectra, time-resolved luminescence, thermal quenching and luminescence decay curves (lifetimes) were applied to characterize the phosphors. The effects of the Ce(3+) ...
Doshi Arpan R - - 2012
For adults with sickle cell disease (SCD), cardiac changes are well described and may account for up to one-fourth of disease-related mortality. Much less is known about heart disease in pediatric SCD patients. This retrospective study analyzed a contemporary cohort of children with SCD followed at a single tertiary care ...
Troshin Konstantin - - 2012
Chiral ion pairs play a key-role in modern enantioselective synthesis though little is known about their properties. We have now used the special features of unsymmetrically substituted allyl derivatives to obtain unprecedented insight in ion pair dynamics. By employing chiral HPLC it was possible to follow the time-dependent concentrations of ...
Xu Shi-Wen - - 2012
Dietary selenium (Se) deficiency can influence the function of the brain. Our objective was to investigate the effects of Se deficiency on oxidative damage and calcium (Ca) homeostasis in brain of chicken. In the present study, 1-day-old chickens were fed either a commercial diet (as control group) with 0.15 mg/kg Se ...
Tranchart Hadrien - - 2012
BACKGROUND: In locally advanced rectal cancer (LARC) patients, major response to neoadjuvant radiotherapy (NR) has been associated with favorable long-term outcomes. Positive pathologic nodal status was recently proven to be associated with poor prognosis even after total regression of primary tumor (ypT0). The aim of this study was to evaluate ...
Lee Seung Duk - - 2012
BACKGROUND: Laparoscopic resection is increasingly being performed for rectal cancer. However, few data are available to compare long-term outcomes after open versus laparoscopic surgery for early-stage rectal cancer. METHODS: Included in this retrospective study were 160 patients who underwent surgery for stage I rectal cancer between 2001 and 2008. Perioperative ...
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