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McEwen Gerald D - - 2012
The nanostructures and hydrophobic properties of cancer cell membranes are important for membrane fusion and cell adhesion. They are directly related to cancer cell biophysical properties, including aggressive growth and migration. Additionally, chemical component analysis of the cancer cell membrane could potentially be applied in clinical diagnosis of cancer by ...
Wang Yuhui - - 2012
We report a new upconversion fluorescence resonance energy transfer (UC-FRET) biosensor using poly-m-phenylenediamine (PMPD) nanospheres as the energy acceptor in this paper. A single-stranded DNA (ssDNA) tagged with a sulfydryl group at 5' terminus was covalently linked to poly-ethylenimine (PEI) functionalized upconversion phosphors (UCPs, the energy donor). Because of the ...
Fartashvand M - - 2012
BACKGROUND: Theileria annulata is a blood parasite affecting ruminants. Hemolytic anemia, secondary hypoxia, and vasculitis are the most important features of tropical theileriosis. OBJECTIVES: Evaluation of electrocardiographic findings and changes in cardiovascular biochemical markers including cTnI concentrations in cattle naturally infected with theileriosis in the absence of acute cardiac failure. ...
Evans C John - - 2012
PURPOSE: To compare the repeatability of γ-aminobutyric acid (GABA) measurements using J-difference editing, before and after spectral realignment-a technique which has previously been demonstrated to improve the quality of J-difference GABA spectra. MATERIALS AND METHODS: We performed in vivo measurements in three brain regions (occipital, sensorimotor, and dorsolateral prefrontal cortex ...
Inai Hiromu - - 2012
OBJECTIVE: To elucidate the patterns of and risk factors for deterioration of renal function after chemotherapy in metastatic testicular cancer survivors using the estimated glomerular filtration rate. METHODS: A total of 96 patients who were treated with cisplatin-based chemotherapy for metastatic testicular cancer between January 1981 and December 2010 were ...
Garg Satish K - - 2012
Objective Peripheral insulin resistance in type 1 diabetes may be related to a paradoxical postprandial glucagon increase. This study evaluated the effects of sitagliptin, (DPP-IV inhibitor, approved for patients with type 2 diabetes), in adults with type 1 diabetes to improve glycemic control through decreasing postprandial glucagon.Methods This investigator-initiated, double-blind, ...
Wise Andrew K - - 2012
Bionic devices electrically activate neural populations to partially restore lost function. Of fundamental importance is the functional integrity of the targeted neurons. However, in many conditions the ongoing pathology can lead to continued neural degeneration and death that may compromise the effectiveness of the device and limit future strategies to ...
Rieder E - - 2012
Background and study aims: Gastrointestinal stents have become an important therapeutic option for several indications. However, migration in up to 40 % of cases represents a significant drawback, especially when covered prostheses are used. We hypothesized that a novel endoscopic suturing device could enable endoluminal stent fixation, which might increase attachment ...
Gogiel Tomasz - - 2012
The extracellular matrix components are differentially distributed among various structures of the umbilical cord. Wharton's jelly is especially rich in collagens and growth factors. Cathepsin B is a major cysteine protease involved in collagen degradation, as well as in the activation of precursor forms of other collagenolytic enzymes and growth ...
Sharma Akhilesh K - - 2012
The stereocontrolling transition state (TS) models for C-C bond formation relying on hydrogen bonding have generally been successful in proline-catalyzed aldol, Mannich, α-amination, and α-aminoxylation reactions. However, the suitability of the hydrogen-bonding model in protic and aprotic conditions as well as under basic and base-free conditions has not been well ...
Rajagopal Sangeerthana - - 2012
Most patients with Tourette syndrome report characteristic sensory experiences (premonitory urges) associated with the expression of tic symptoms. Despite the central role of these experiences to the clinical phenomenology of Tourette syndrome, little is known about their underlying brain processes. In the present article we present the results of a ...
Lavagnino Michael - - 2012
Tendon laxity following injury, cyclic creep, or repair has been shown to alter the normal homeostasis of tendon cells which can lead to degenerative changes in the extra-cellular matrix. While tendon cells have been shown to have an inherent contractile mechanism which gives them some ability to re-tighten lax tendons ...
Tahayori Bahman - - 2012
The validity of approximate equations describing the membrane potential under extracellular electrical stimulation (Meffin et al 2012 J. Neural Eng. 9 065005) is investigated through finite element analysis in this paper. To this end, the finite element method is used to simulate a cylindrical neurite under extracellular stimulation. Laplace's equations ...
Wirges Markus - - 2012
Incorporation of an active pharmaceutical ingredient (API) into the coating layer of film-coated tablets is a method mainly used to formulate combination tablets. Uniform and precise spray coating of an API represents, however, a substantial challenge that could be overcome by applying Raman spectroscopy as process analytical tool. In the ...
Hong Ying - - 2012
ABSTRACT Purpose: To study the possible mechanism and treatment for pigment dispersion glaucoma (PDG) caused by single-piece acrylic (SPA) intraocular lens (IOL) ciliary sulcus fixation in Asian eyes. Materials and methods: Patients referred for PDG caused by SPA IOL ciliary sulcus fixation to our hospital from April 2005 to June ...
Christou E - - 2012
We present a case of non-involuting congenital haemangioma (NICH) of the right eyelid which was present at birth as a purpuric macule but increased in size to cause significant obstruction of vision. At four years of age the lesion was treated with fluroscopic ultrasound-guided sclerotherapy using 0.5% sodium tetradecyl suphate ...
Cavanna Andrea E - - 2012
Tourette syndrome (TS) is a neurological condition first described by Georges Gilles de la Tourette in 1885. TS was largely thought of as a rare and bizarre condition until the 1960s, when the beneficial effects of neuroleptics on tic symptoms led to an exponential increase in neuroscientific research. Today TS ...
Liu Yuyang - - 2012
This paper reports on the fabrication of cotton fabrics with single-faced superhydrophobicity using a simple foam finishing process. Unlike most commonly reported superhydrophobic fabrics, the fabrics developed in this study exhibit asymmetric wettability on their two faces: one face showing superhydrophobic behaviors (highly non-wetting or water-repellent characteristics) and the other ...
Chen Shih-Pin - - 2012
In this study, a simple and effective silver ink formulation was developed to generate silver tracks with high electrical conductivity on flexible substrates at low sintering temperatures. Diethanolamine (DEA), a self-oxidizing compound at moderate temperatures, was mixed with silver ammonia solution to form a clear and stable solution. After inkjet-printed ...
Wang Hao - - 2012
An overview of the municipal solid waste (MSW) management in Beijing, a city with a resident population of about 19.61 million in 2010, is presented in the article. Economic development and population growth have resulted in a MSW generation increase from 2.96 million tons in 2000 to 6.20 million tons ...
Bonvin Florence - - 2012
The presence of potentially persistent and bioactive human metabolites in surface waters gives rise to concern; yet little is known to date about the environmental fate of these compounds. This work investigates the direct photolysis of human metabolites of the antibiotic sulfamethoxazole (SMX). In particular, we determined photolysis kinetics and ...
Ciardelli Francesco - - 2012
The detection of mechanical stress in polymeric materials through optical variations has attracted considerable interest over the past ten years. In this tutorial review, the current state of knowledge concerning the preparation of polymers with mechanochromic features is summarized. Two types of procedures are illustrated and thoroughly discussed along with ...
Omran Nahla Ee - - 2012
Holothuria polii (Delle Chiaje, 1823) (Holothuriidae) is a sea cucumber inhabiting Mediterranean Sea coast of Egypt. The bioactive compound of its tegument has antifungal, antibacterial and antiparasitic effects. The present study aims to elucidate the structure of the bioactive material of H. polii for pharmacological and chemotaxonomic purposes. Furthermore, the ...
Harvey Samuel B - - 2012
Reserve and National Guard forces have been mobilized to an unprecedented degree in recent overseas conflicts. There is concern that rates of psychological problems may continue to rise for many years after deployment. The authors conducted a cohort study of 552 United Kingdom Reservists who deployed to Iraq in 2003 ...
Borges Clarissa Araújo - - 2012
Abstract Escherichia coli is a pathogen of major importance in swine and public health. To determine the prevalence of Shiga toxigenic E. coli (STEC) and enteropathogenic E. coli (EPEC), samples were collected from the feces and carcasses of swines. In total, 441 samples were collected in four samplings, of which ...
Curtin Vincent - - 2012
The co-processing of active pharmaceutical ingredient (API) with an excipient which has a high glass transition temperature (Tg) is a recognised strategy to stabilise the amorphous form of a drug. This work investigates whether co-processing a model API, sulfadimidine (SDM) with a series of low Tg excipients prevents or reduces ...
Basal Seref - - 2012
WHAT'S KNOWN ON THE SUBJECT? AND WHAT DOES THE STUDY ADD?: Removing of prostate for the treatment of localized prostate cancer is associated with a variable loss of erectile function due to injury of the nerves of erection during operation. Some researchers have reported that after nerve-sparing radical prostatectomy (RP), ...
Urdaneta-Moncada Alfonso - - 2012
Dural arteriovenous fistulas (DAVFs) are abnormal connections between arteries and veins that are classified by location, morphology or direction of venous drainage. Treatment of DAVFs is undertaken in patients with severe symptoms or those with retrograde cortical venous drainage and/or venous ectasia. Much is written regarding the treatment of DAVFs ...
Lajoie Mathieu - - 2012
ABSTRACT: Approaches for regulatory element discovery from gene expression data usually rely on clustering algorithms to partition the data into clusters of co-expressed genes. Gene regulatory sequences are then mined to find over-represented motifs in each cluster. However, this ad-hoc partition rarely fits the biological reality. We propose a novel ...
Trivedi Ruchit - - 2012
Our purpose was to assess sustained delivery and enhanced efficacy of pirfenidone-loaded nanoparticles after intratracheal instillation.Poly(lactide-co-glycolide) nanoparticles containing pirfenidone (NPs) were prepared and characterized. Biodistribution of NPs and solution was assessed using LC-MS after intratracheal administration in C57Bl/6 mice at 3 and 24 h and 1 week post-administration. Efficacy was tested ...
Shepherd Robert K - - 2012
The full text of the Preface is given in the PDF file. References [1] Nagayam B A et al 2012 J. Neural Eng. 9 065001 [2] Wise A K et al 2012 J. Neural Eng. 9 065002 [3] Davis T S et al 2012 J. Neural Eng. 9 065003 [4] ...
Stelzle Florian - - 2012
OBJECTIVES: Piezoelectric surgery (PS) is meant to be a gentle osteotomy method. The aim of this study was to compare piezosurgical vs. conventional drilling methods for implant site preparation (ISP) - focusing on load-dependent thermal effect on hard tissue and the expenditure of ISP time. MATERIALS AND METHODS: Three hundred ...
Venskutonyte Laura - - 2012
The second Diabetes Glucose and Myocardial Infarction (DIGAMI 2) study randomised patients with diabetes and myocardial infarction to insulin or oral-based treatment. To determine the effects of insulin-based treatment, the Diabetes Treatment Satisfaction Questionnaire (DTSQ) and the Psychological General Well-Being (PGWB) Index were administered at baseline and 12 months. Insulin-treated ...
Tingberg A - - 2012
Image monitors and viewing boxes have a crucial role in the diagnostic process. Modern radiology uses different modalities to produce digital images which are to be viewed in different parts of the radiology department and throughout the hospital, sometimes simultaneously, via the Picture Archiving and Communications System (PACS). Therefore, the ...
Jiang Qike - - 2012
Two kinds of laser diodes (LDs) comprised of ZnO/MgxZn1-xO (ZnO/MZO) multiple quantum wells (MQWs) grown on GaN (MQWs/GaN) and Si (MQWs/Si) substrates, respectively, have been constructed. The LD with MQWs/GaN exhibits ultraviolet random lasing under electrical excitation while that with MQWs/Si nearly not. In the MQWs/Si, ZnO/MZO MQWs are consisted ...
Sun Grace E Ching - - 2012
Objective: To report a rare case of hypophosphatemic rickets (HR) leading to extensive cardiac complications.Methods: We present the clinical course and autopsy findings of a patient with HR, treated with chronic phosphate-only therapy as a child, who subsequently developed tertiary hyperparathyroidism leading to extensive cardiac calcifications and complications. We also ...
VAN Haelst I M M - - 2012
BACKGROUND: This study aimed to explore the occurrence and determinants of poor response to short-term pre-operative erythropoietin treatment and the effect of such poor response on transfusion in total hip arthroplasty patients. METHODS: We studied total hip arthroplasty patients who received erythropoietin before surgery. The primary outcome was the pre-operative ...
Lindkvist Ida - - 2012
Informal payments-payments made from patients to health personnel in excess of official fees-are widespread in low-income countries. It is not obvious how such payments affect health worker effort. On the one hand, one could argue that because informal payments resemble formal pay for performance schemes, they will incite higher effort ...
Lam W L - - 2012
Reconstruction of digital defects using the venous flap offer several advantages but remained unpopular owing to levels of venous congestion rates. We performed animal studies to test the hypothesis that an arterio-venous shunt increases pressure for peripheral flap perfusion and decreases venous congestion. Using an abdominal adipofascial flap model in ...
Kabar I - - 2012
Biliary anastomotic strictures after liver transplantation are a major source of morbidity and graft failure; however, repeated endoscopic therapy has shown variable long-term success rates. Thus the aim of this prospective case series was to evaluate the safety and efficacy of using paclitaxel-eluting balloons in 13 patients requiring treatment for ...
Leung Angela Ym - - 2012
AIMS AND OBJECTIVES: To develop and to test the psychometric properties of the Chinese Health Literacy Scale for Diabetes. BACKGROUND: Patients with diabetes encounter many challenges when making health decisions in their daily lives, as they have access to many different kinds of health information. Health literacy issues are new ...
Horwich Peter - - 2012
BACKGROUND AND AIM: We sought to evaluate the long-term impact of post-cardiac surgery atrial fibrillation on the risk of stroke and survival. METHODS: Patients undergoing isolated CABG surgery from April 1, 1995 to March 31, 2007 were identified (n = 8058). Long-term stroke data were compiled using Cox modeling adjusted for clinical ...
Langan Russell C - - 2012
INTRODUCTION: Autosomal dominant hyperimmunoglobulinemia E syndrome (HIES), also called Job's syndrome, is a primary immunodeficiency characterized by the triad of elevated immunoglobulin E levels, eczema, and infections. Its clinical course manifests as recurrent skin and pulmonary infections, and variable skeletal, connective tissue, and vascular abnormalities. There is evidence of abnormal ...
Zhu Hong - - 2012
Simple, fast, and sensitive HPLC coupled with an electrospray ionization tandem mass spectrometry (HPLC-ESI-MS/MS) method for the simultaneous determination of cnidilin and its two metabolites, 3″,8-methoxy-isoimperatorin (M1) and 5″-hydroxyl-8-methoxy-isoimperatorin (M2), in rat plasma has been developed. Pimpinellin was used as the internal standard and the total analysis time was 7 min. ...
Brandsma Henk-Thijs - - 2012
ABSTRACT: BACKGROUND: Parastomal hernia is a common complication of a colostomy. Ultimately, one-third of patients with a parastomal hernia will need surgical correction due to frequent leakage or life-threatening bowel obstruction or strangulation. However, treatment remains a challenge resulting in high recurrence rates. Two single center trials demonstrated that the ...
Halboos A - - 2012
History and clinical findings: A 69-year-old man came to the emergency unit because of vertigo and presyncope. A bipolar disorder - known since an age of 15 years - has been treated with 2 × 450 mg lithium and 100 mg perazine per day for several years (no other medications). With the ...
Rémond Marc Gerard - - 2012
ABSTRACT: BACKGROUND: In Australia, rheumatic heart disease (RHD) is almost exclusively restricted to Aboriginal Australian and Torres Strait Islander people with children being at highest risk. International criteria for echocardiographic diagnosis of RHD have been developed but the significance of minor abnormalities which do not reach these criteria remains unclear. ...
Klusek Jessica - - 2012
While there is a strong sex bias in the presentation of autism, it is unknown whether this bias is also present in subclinical manifestations of autism among relatives, or the broad autism phenotype. This study examined this question and investigated patterns of co-occurrence of broad autism phenotype traits within families ...
Dermitzakis Konstantinos - - 2012
Abstract Physiological studies of the human finger indicate that friction in the tendon-pulley system accounts for a considerable fraction of the total output force (9-12%) in a high-load static posteccentric configuration. Such a phenomenon can be exploited for robotic and prosthetic applications, as it can result in (1) an increase ...
Silva-Herdade A S - - 2012
Acetylcholinesterase (AChE) is found both on the membranes of neuronal and non-neuronal cells. In this study we performed intravenous administrations of velnacrine (VLN) and acetylcholine (ACh), respectively, AChE inhibitor and substrate, in an animal model of lipopolysaccharide (LPS)-induced inflammation in Wistar rats. Using intravital microscopy the number of rolling and ...
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