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Results 501 - 550 of 2827
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Peng Xiang-Qian - - 2012
To expand the functionality of lipase B from Candida antarctica (CALB), we used the multi-site saturation mutagenesis methods to create CALB mutants with improved thermal stability. The times of residual activity of the mutants mCALB168 and mCALB7 were 14 and 6 times higher than that of the displayed WT-CALB at ...
Soussan Michael - - 2012
BACKGROUND: We hypothesized that a high-fat and low-carbohydrate (HFLC) diet before FDG-PET/CT could identify patients with active cardiac sarcoidosis (CS). METHODS: Fifty-eight sarcoidosis patients with a suspicion of CS consumed a HFLC diet before FDG-PET/CT. Clinical, electrical, and other imaging investigations were compared to PET results. RESULTS: Using Japanese Ministry ...
Yan Xiaoyu X Department of Pharmaceutical Sciences School of Pharmacy and Pharmaceutical Sciences, University at Buffalo, 370 Kapoor Hall, Buffalo, New York 14214, - - 2013
The purpose of this study is to demonstrate that the erythroid precursor depletion in bone marrow induced by recombinant human erythropoietin (rHuEPO) treatment may be another contributing factor to erythropoietin hyporesponsiveness. Healthy Wistar rats were given single dose (SD) or multiple doses (MD) of rHuEPO (100 IU/kg). In MD study, ...
Yu Yong - - 2012
Here we report the use of sulfuric acid as a catalyst for the facile and homogeneous synthesis of core-shell SiO(2)@TiO(2) nanocomposites using simple apparatus, under ambient pressure and temperature. The resultant SiO(2)@TiO(2) exhibits an ideal core-shell structure with uniform nanoscale TiO(2) coverage. The shell thickness of SiO(2)@TiO(2) can be conveniently ...
Toscano Giuseppe - - 2012
Propylene glycol (PG) is a main component of aircraft deicing fluids and its extensive use in Northern airports is a source of soil and groundwater contamination. Bacterial consortia able to grow on PG as sole carbon and energy source were selected from soil samples taken along the runways of Oslo ...
Poulsen Jon W - - 2012
Protein digestion is an integral part of the 'shotgun' proteomics approach and commonly requires overnight incubation prior to mass spectrometry analysis. Quadruplicate 'shotgun' proteomic analysis of whole yeast lysate demonstrated that Guanidine-Hydrochloride (Gnd-HCl) protein digestion can be optimally completed within 30 minutes with endoprotease Lys-C. No chemical artifacts were introduced ...
Kalinkat Gregor - - 2012
The question whether top-down or bottom-up forces dominate trophic relationships, energy flow, and abundances within food webs has fuelled much ecological research with particular focus on soil litter ecosystems. Because litter simultaneously provides habitat structure and a basal resource, disentangling direct trophic and indirect non-trophic effects on different trophic levels ...
Hammerstad Sara Salehi - - 2012
BACKGROUND: Transient postoperative hypocalcemia is one of the most common complications after thyroidectomy. Permanent hypocalcemia, however, is rare, but usually requires life-long treatment and follow-up. The risk of permanent hypocalcemia has been shown to be significantly higher in patients with Graves' disease. In the present study we evaluated short-term and ...
Beas-Catena A - - 2012
Spodoptera exigua Se301 cells have been successfully adapted to two different commercial serum-free media (SFM; Ex-Cell 420 and Serum-Free Insect Medium-1) by gradually reducing the 10 %-added serum-containing medium content from 100 % to 0 % (v/v) in suspended cultures. Both direct adaptation to a serum-free medium and cell growth in the absence ...
Chaudhary Sushant - - 2012
PURPOSE: Single-incision laparoscopic cholecystectomy (SILC) was first described in 1999. Many techniques using newer instruments have emerged but none has been standardized. We describe our technique and experience, using non-articulating instruments with conventional trocars. METHOD: Patients who underwent SILC over 2 years (July 2009-July 2011) were included in the study group. ...
Eteuati J - - 2012
BACKGROUND: Brachial plexopathy may be caused by malpositioning during surgery when the body's protective mechanism is lost under general anaesthesia. It is the second commonest nerve injury reported in the anaesthetized patient. The exact incidence in colorectal surgery is unclear but there have been numerous cases reported of brachial plexopathy ...
Al-Farsi Yahya M - - 2012
Toxic levels of heavy metals and low levels of essential minerals have been suggested to play a critical role in the pathogenesis of autism spectrum disorders (ASD). This study documents the levels of heavy metals and essential minerals in hair samples of children with ASD in Muscat, the urbanized capital ...
O'Neill A C - - 2012
BACKGROUND: Women younger than 30 years with a focal breast finding have a low incidence of malignancy. Targeted ultrasound is an accurate primary imaging test. MATERIALS AND METHODS: All breast ultrasounds performed from July 1, 2011 to September 30, 2011 were reviewed. All ultrasounds in patients under 25 years were ...
Addeo Pietro - - 2012
BACKGROUND: Repeat repair of bile duct injuries (BDIs) after cholecystectomy is technically challenging, and its success remains uncertain. We retrospectively evaluated the short- and long-term outcomes of patients requiring reoperative surgery for BDI at a major referral center for hepatobiliary surgery. METHODS: Between January 1991 and May 2011, we performed ...
Hernandez Adrian F AF Duke Clinical Research Institute, Duke University School of Medicine, Durham, North Carolina 27715, USA. - - 2012
Aldosterone antagonist therapy for heart failure and reduced ejection fraction has been highly efficacious in randomized trials. However, questions remain regarding the effectiveness and safety of the therapy in clinical practice. To examine the clinical effectiveness of newly initiated aldosterone antagonist therapy among older patients hospitalized with heart failure and ...
Rodríguez-Ramiro Ildefonso - - 2012
Numerous lines of evidence support a relationship between intestinal inflammation and cancer. Therefore, much attention has recently been focused on the identification of natural compounds with anti-inflammatory activities as a strategy to suppress the early stages of colorectal cancer. Because cocoa is a rich source of bioactive compounds, the present ...
Sahariah Munima B - - 2012
The structural stabilities, elastic, electronic and magnetic properties of the Heusler-type shape memory alloy Ni(2)FeGa are calculated using density functional theory. The volume conserving tetragonal distortion of the austenite Ni(2)FeGa find an energy minimum at c/a = 1.33. Metastable behaviour of the high temperature cubic austenite phase is predicted due to elastic ...
Goldberg Ximena - - 2012
Childhood maltreatment and low socioeconomic status (SES) are considered stressful environmental events with lasting detrimental effects on adult mental health and associated cognitive performance, such as memory. However, the association between childhood maltreatment and low SES remains unclear, probably due to design limitations and putative confounding factors. Particular concerns have ...
Basly Brice - - 2012
Aqueous suspensions of dendronized iron oxide nanoparticles (NPs) have been obtained after functionalization, with two types of dendrons, of NPs synthesized either by coprecipitation (leading to naked NPs in water) or by thermal decomposition (NPs in situ coated by oleic acid in an organic solvent). Different grafting strategies have been ...
Fradua Luis - - 2012
Abstract The aims of this study were to examine the 1) individual playing area, 2) length and width of the rectangle encompassing the individual playing area and 3) distance between the goalkeepers and their nearest team-mates during professional soccer matches and compare these to previously reported pitch sizes for small-sided ...
Schmidt Peter J PJ Section on Behavioral Endocrinology, National Institute of Mental Health, National Institutes of Health, Department of Health & Human Services, Bethesda, MD 20892-1277, USA. - - 2013
Gynecology clinic-based studies have consistently demonstrated that induced hypogonadism is accompanied by a decline in cognitive test performance. However, a recent study in healthy asymptomatic controls observed that neither induced hypogonadism nor estradiol replacement influenced cognitive performance. Thus, the effects of induced hypogonadism on cognition might not be uniformly experienced ...
Marina Nephtali N Neuroscience, Physiology and Pharmacology, University College London, London WC1E 6BT, - - 2013
Heart failure may lead to hypoperfusion and hypooxygenation of tissues and this is often exacerbated by central and obstructive sleep apnoeas associated with recurrent episodes of systemic hypoxia which triggers release of ATP within the CNS circuits controlling sympathetic outflow. Using in vitro and in vivo models we tested two ...
Zhu Chunyu - - 2012
Nonstructural protein 1 (NS1) is a non-structural protein of avian influenza virus. It can interact with a variety of proteins of the host cells, enhancing the expression of viral proteins and changing the growth and metabolism of the host cells, thereby enhancing the virus' pathogenicity and virulence. To investigate whether ...
Kuwayama Kenji - - 2012
The aim of this study was to determine whether an ingested drug and its metabolites could be detected in the subject's fingerprints. Caffeine (CF) was chosen as the model drug. Three healthy subjects were asked to consume a cup of coffee (ca. 100 mL) containing 80 micro micro mg CF as the total ...
Mishra A K - - 2012
Brain abscess represents a significant medical problem, despite recent advances made in detection and therapy. Streptococcus intermedius, a commensal organism, has the potential to cause significant morbidity. S. intermedius expresses one or more members of a family of structurally and antigenically related surface proteins termed antigen I/II, which plays a ...
Banda Me - - 2012
Abstract AIM: To describe a temporal cluster of avian malaria (Plasmodium spp.) at an Operation Nest Egg™ (ONE) site in Rotorua which caused mortality in a juvenile kiwi and had high population prevalence in brown kiwi (Apteryx mantelli). METHODS: A 70-day-old wild-born captive brown kiwi was submitted for post-mortem examination ...
Haggård L - - 2012
We aimed at evaluating whether β-glucans could improve low-density lipoprotein (LDL) cholesterol levels and/or glycemic control in patients with myasthenia gravis (MG), in whom statins usually have muscle-related side effects. Fifty-nine MG patients participated in the study and received a daily dietary supplement of 3 g of β-glucans during 8 weeks. ...
Zheng Zhixiang - - 2012
A facile and green method was developed to synthesize the graphene-carbon nanotubes (Gr-CNTs) nanocomposite with a sandwich lamination structure. Pt nanoparticles were loaded on the as-synthesized Gr-CNTs nanocomposite to prepare an electrochemical sensor for determining bisphenol A (BPA) in thermal printing paper. The electrochemical behavior of BPA on the Pt/Gr-CNTs ...
Ganor Y - - 2012
The penile urethra is routinely targeted by sexually transmitted bacterial and viral pathogens, and also represents a probable site for HIV type-1 (HIV-1) entry. Yet, the mechanisms of urethral HIV-1 transmission are unknown. To describe the initial steps of penile HIV-1 entry, we obtained whole penile tissues from individuals undergoing ...
Mogi Ai - - 2012
Malignant cells supply their energy needs through increased glucose consumption, producing large quantities of lactic acid via glycolysis. Glucose transporters (GLUTs) and monocarboxylate transporters (MCTs) are therefore commonly up-regulated in human malignancies to mediate glucose influx and lactic acid efflux, respectively. However, their roles in malignant pleural mesothelioma (MPM) have ...
Chavhan Govind B - - 2012
Postoperative bile leaks are difficult to diagnose because signs and symptoms are nonspecific, and definitive diagnosis requires a drainage catheter to be placed that drains frank bile or fluid that turns out bile on laboratory analysis. Hepatobiliary scintigraphy, endoscopic retrograde cholangiopancreatography (ERCP) and percutaneous transhepatic cholangiography (PTC) have been traditionally ...
Tenlen Jennifer R JR Department of Biology, University of North Carolina-Chapel Hill, NC 27599, USA. - - 2013
How morphological diversity arises is a key question in evolutionary developmental biology. As a long-term approach to address this question, we are developing the water bear Hypsibius dujardini (Phylum Tardigrada) as a model system. We expect that using a close relative of two well-studied models, Drosophila (Phylum Arthropoda) and Caenorhabditis ...
Wu Su Fang - - 2012
PURPOSE: Cervical carcinoma is the second most prevalent and the fifth most deadly malignancy seen in women worldwide. Dysregulated activation of EGF ErbB system has been implicated in diverse types of human cancer; however, it is elusive how it is regulated in human cervical cancer cells. We herein aimed to ...
Gorin Michael A - - 2012
PURPOSE: To describe the frequency and severity of atherosclerosis contained within the non-neoplastic tissue of partial nephrectomy (PN) specimens. METHODS: Archived open PN specimens were evaluated for histological evidence of atherosclerosis. Clinically significant atherosclerosis was defined as arterial luminal narrowing of >25 % due to fibrointimal thickening. Histological findings were correlated ...
Halbfass Philipp - - 2012
Three-dimensional (3-D) mapping systems are of great value for the diagnosis and ablation of cardiac arrhythmias. If applied appropriately, 3-D mapping systems (3DM) can reduce fluoroscopy and procedural time. In general, two advanced mapping systems are currently in use: the CARTO™ system (Biosense Webster) uses ultralow-intensity magnetic fields to locate ...
He Chaoyu - - 2012
Using the first-principles method, we investigate the energetic stability, dynamic stability and electronic properties of two viable three-dimensional (3D) carbon semiconductors with an entirely sp(2) configuration, sp(2)-diamond and cubic-graphite. Both allotropes are more stable than the previously proposed K4-carbon and T-carbon and were confirmed to be dynamically stable. Interestingly, sp(2)-diamond ...
Zhen-Bo Tu - - 2012
Background/Aims: To clarify any association between the hOGG1 Ser326Cys polymorphism and susceptibility to hepatocellular carcinoma (HCC). Methodology: The PubMed, CNKI databases were searched for all available articles. The OR corresponding to the 95% confidence interval (95% CI) was used to assess the association between hOGG1 Ser326Cys polymorphism and susceptibility to ...
Deary Michael E - - 2012
Our recent work has provided new insights into the equilibria and species that exist in aqueous solution at different pHs for the boric acid - hydrogen peroxide system, and the role of these species in oxidation reactions. Most recently, (M. C. Durrant, D. M. Davies and M. E. Deary, Org. ...
Wang Feng - - 2012
The mycelia of Trametes versicolor immobilized in alginate beads provided higher laccase production than that in pelleted form. An efficient ultrasonic treatment enhanced laccase production from the immobilized T. versicolor cultures. The optimized treatment process consisted of exposing 36-h-old bead cultures to 7-min ultrasonic treatments twice with a 12-h interval ...
Adeniyi Adebayo A - - 2012
In this work several quantum properties including the NEDA and QTAIM are computed on three models of rapta-C complexes using DFT with hybrid functional and basis set with ECP and without ECP. Several interesting correlations within the observed properties and also with the reported experimental behaviors of these complexes including ...
Arias-Diaz Javier J Instituto de Salud Carlos III (ISCIII), Madrid, Spain. - - 2013
The Spanish regulatory framework for storage of samples for research responds to most issues raised by both researchers and society regarding biobanking. The Spanish regulation currently foresees three possible ways in which these samples are to be handled: (a) gathering for use in a specific project, (b) storage in a ...
Zheng Yingfeng - - 2012
The Guangzhou Twin Registry is a population-based registry of twins residing in Guangzhou City. The initial registry database included 9,700 pairs of young twins recruited from the Official Household Registry of Guangzhou City. The registry is designed to provide a resource to identify the genetic and environmental causes of common ...
Pfister Roland R Department of Psychology III, Julius-Maximilians University of Würzburg, Röntgenring 11, 97070, Würzburg, Germany. - - 2013
Voluntary actions are guided by sensory anticipations of body-related as well as environment-related action effects. Even though action effects in the environment typically resemble the action goal proper, anticipations of body-related effects can cause interference if they do not correspond to intended environment-related effects. The present study explored which specific ...
Hur Yoon-Mi - - 2012
Twin studies of Africans have been scarce although Africans have shown the highest twin birth rate in the world. As a parallel study of the South Korean Twin Registry, the Nigerian Twin and Sibling Registry (NTSR) was developed to understand causal influences on the development of cognitive abilities, personality, and ...
Feng Ran - - 2012
In this paper, the origins of enantioselectivity in asymmetric ketone hydrogenation catalyzed by RuH(2)(binap)(cydn) (cydn = trans-1,2-diaminocyclohexane) were discussed. Fifteen substrates involving aromatic, heteroaromatic, olefinic and dialkyl prochiral ketones were used to probe the catalytic mechanism and find an effective way to predict the chirality of the products. The calculated ...
Cai Kebo - - 2012
The aim of this study was to explore whether IL-7 participates in the pathogenesis of Graves' ophthalmopathy (GO). This was a prospective study. 20 GO patients (40 eyes) and 20 healthy volunteers (40 eyes) were recruited. The tear concentration of IL-7 was measured using ELISA assay. IL-7 expression in orbital ...
Siwek Agata - - 2012
The preliminary cytotoxic effect of 4-ethoxycarbonylmethyl-1-(piperidin-4-ylcarbonyl)-thiosemicarbazide hydrochloride (1)-a potent topoisomerase II inhibitor-was measured using a MTT assay. It was found that the compound decreased the number of viable cells in both estrogen receptor-positive MCF-7 and estrogen receptor-negative MDA-MB-231breast cancer cells, with IC(50) values of 146 ± 2 and 132 ± 2 μM, respectively. To clarify ...
Blasi Francesca - - 2012
Product authenticity is an important topic in dairy sector. Dairy products sold for public consumption must be accurately labelled in accordance with the contained milk species. Linear discriminant analysis (LDA), a common chemometric procedure, has been applied to fatty acid% composition to classify pure milk samples (cow, ewe, buffalo, donkey, ...
Tuong William - - 2012
This systematic review examines the effectiveness of videos in modifying health behaviors. We searched PubMed (1975-2012), PsycINFO (1975-2012), EMBASE (1975-2012), and CINAHL (1983-2012) for controlled clinical trials that examined the effectiveness of video interventions in changing health behaviors. Twenty-eight studies comprised of 12,703 subjects were included in the systematic review. ...
Munoz Carlos - - 2012
The inward rectifier K(+) channel Kir2.1 contributes to the maintenance of the resting cell membrane potential in excitable cells. Loss of function mutations of KCNJ2 encoding Kir2.1 result in Andersen-Tawil syndrome, a disorder characterized by periodic paralysis, cardiac arrhythmia, and dysmorphic features. The ubiquitously expressed protein kinase B (PKB/Akt) activates ...
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