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Results 401 - 450 of 2118
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Scalise F - - 2012
OBJECTIVES: Chronic cerebrospinal venous insufficiency (CCSVI) is a malformative condition characterized by several anomalies of the azygos and/or internal jugular veins (IJVs). Recommended diagnosis of CCSVI is performed with colour-Doppler (CD) sonography. Though catheter venography (CV) is considered as the gold standard for determining vascular anatomy, its uniplanar point of ...
Leitritz Martin A - - 2013
To investigate the long term effectiveness of grid laser photocoagulation (GLP) versus intravitreal bevacizumab (BEV) in macular oedema (MO) secondary to branch retinal vein occlusion (BRVO), and to evaluate the treatment courses after treatments were switched. In this prospective interventional consecutive case series, previously untreated eyes with perfused MO were ...
Liu Bo - - 2012
PURPOSE: Muller glia respond to retinal injury by a reactive gliosis but only rarely do mammalian glial cells re-enter the cell cycle and generate new neurons. In the non-mammalian retina, however, Muller glia act as stem/progenitor cells. Here, we test the function of Wnt signaling in the post-injury retina, focusing ...
Reboud V - - 2012
We report on a method to enhance the light-emission efficiency of printable thin films of a polymer doped with luminescent (CdSe)ZnS nanocrystals via metallic nanoparticles and nanoimprinted photonic crystals. We experimentally show a strong fluorescence enhancement of nanocrystals by coupling exciton-plasmon with the localized surface plasmon of metallic nanoparticles. The ...
Casey Darren P DP Department of Anesthesiology, Mayo Clinic, Rochester, Minnesota 55905, USA. - - 2013
Large increases in systemic oxygen content cause substantial reductions in exercising forearm blood flow (FBF) due to increased vascular resistance. We hypothesized that 1) functional sympatholysis (blunting of sympathetic α-adrenergic vasoconstriction) would be attenuated during hyperoxic exercise and 2) α-adrenergic blockade would limit vasoconstriction during hyperoxia and increase FBF to ...
Uysal Ahmet - - 2012
Background/Aims: Thalassemia is one of the most common hereditary disorders in Turkey. The aim of our study was to determine the prevalence of the β-thalassemia trait and abnormal hemoglobin in couples who applied for premarital screening in the third largest Turkish province of Izmir in the Aegean region. Methods: From ...
Abdel-Latif M E - - 2012
OBJECTIVE: To compare neurodevelopmental outcomes of extremely preterm infants conceived after assisted conception (AC) compared with infants conceived spontaneously (non-AC). DESIGN: Population-based retrospective cohort study. SETTING: Geographically defined area in New South Wales and the Australian Capital Territory, Australia served by a network of 10 neonatal intensive care units. PATIENTS: ...
Podberezin Mark - - 2012
Context.-Cancer stem cells (CSCs) comprise a minor cell population in a tumor; however, they possess self-renewal capacity and are responsible for tumor recurrence and the emerging issue of tumor resistance. Despite recent advances in the study of pathogenesis and mechanisms of CSC-mediated disease recurrence and multidrug resistance, many questions remain ...
Beyer Mona K MK Norwegian Centre for Movement Disorders, Stavanger University Hospital, Stavanger, Norway. - - 2013
Cognitive impairment, including impairment of episodic memory, is frequently found in newly diagnosed Parkinson's disease (PD). In this longitudinal observational study we investigated whether performance in memory encoding, retention, recognition and free recall is associated with reduced hippocampal radial distance. We analysed baseline T1-weighted brain MRI data from 114 PD ...
Zerweck Christof - - 2012
BACKGROUND: Endovenous Laser Ablation (EVLA) is one of the most accepted treatment options for varicose veins. The aim of this study was to investigate the efficacy and safety of the new radial fiber slim (ELVeS-radial-slim kit(TM)) for the 1470 nm diode laser in perforator veins with a 1 month follow-up. ...
Porta Camillo - - 2012
Objectives: This study included a cohort of advanced renal cell carcinoma patients treated with sunitinib. Since resistance to sunitinib may be mediated through angiogenic cytokines other than VEGF, we measured the circulating levels of three pro-angiogenic cytokines: basic fibroblast growth factor (bFGF), hepatocyte growth factor (HGF), and interleukin (IL)-6. Methods: ...
Rupp Thomas - - 2013
Performing exercise during the first hours of hypoxic exposure is thought to exacerbate acute mountain sickness (AMS), but whether this is due to increased hypoxemia or other mechanisms associated with exercise remains unclear. In 12 healthy men, AMS symptoms were assessed during three 11-h experimental sessions: 1) in Hypoxia-exercise, inspiratory ...
Slagt Cornelis - - 2012
To evaluate the 3.02 software version of the FloTrac/Vigileo™ system for estimation of cardiac output by uncalibrated arterial pressure waveform analysis, in septic shock. Nineteen consecutive patients in septic shock were studied. FloTrac/Vigileo™ measurements (COfv) were compared with pulmonary artery catheter thermodilution-derived cardiac output (COtd). The mean cardiac output was ...
Holmberg Johan J Muscle Biology Unit, Department of Experimental Medical Science, Lund University, Lund, Sweden. - - 2013
A chain is no stronger than its weakest link is an old idiom that holds true for muscle biology. As the name implies, skeletal muscle's main function is to move the bones. However, for a muscle to transmit force and withstand the stress that contractions give rise to, it relies ...
Boers Maarten - - 2012
BACKGROUND/OBJECTIVE: Treatment of rheumatoid arthritis (RA) with tumour necrosis factor (TNF) antagonists changes the relationship between disease activity and progression of radiological joint damage ('disconnect'): patients who have little or no response of disease activity still show reductions in damage progression. In early RA, the COBRA strategy (combination of methotrexate ...
Grossman Daniel A - - 2012
Objectives. We assessed the effect of a telemedicine model providing medical abortion on service delivery in a clinic system in Iowa. Methods. We reviewed Iowa vital statistic data and billing data from the clinic system for all abortion encounters during the 2 years prior to and after the introduction of ...
Reed Carrie C Department of Epidemiology, Boston University School of Public Health, Boston, MA 02118, - - 2013
We investigated potential risk factors for active injection drug use (IDU) in an inner-city cohort of patients infected with hepatitis C virus (HCV). We used log-binomial regression to identify factors independently associated with active IDU during the first 3 years of follow-up for the 289 participants who reported ever having ...
Burrows Malcolm - - 2012
The kinematics and jumping performance of treehoppers (Hemiptera, Auchenorrhyncha, Membracidae) were analysed from high speed images. The 8 species analysed had an 11 fold range of body mass (3.8 mg to 41 mg) and a 2 fold range of body lengths (4.1 to 8.4 mm). Body shape was dominated by ...
Ozkaya Abdullah - - 2012
Abstract Purpose: To compare the effects of straight, oblique, and double-plane tunnel scleral intravitreal injection techniques, on short-term intraocular pressure (IOP) changes, occurrence of vitreous reflux (VR), and/or other complications. Methods: A total of 105 patients were included in this prospective study. Patients were assigned randomly to one of the ...
Brewer Philip B - - 2012
With the discovery of strigolactones as root exudate signals that trigger parasitic weed seed germination, and then as a branching inhibitor and plant hormone, the next phase of strigolactone research has quickly revealed this hormone class as a major player in optimizing plant growth and development. From the early stages ...
Szilágyi Melinda - - 2012
Carbon starvation is a common stress both in the Nature and in the industry. Carbon starvation stress response (CSSR) involves the regulation of several important processes including programmed cell death and reproduction of fungi, secondary metabolit production and extracellular hydrolase formation. To gain insight into the physiological events of CSSR ...
Martins Thomas B - - 2012
Patients with therapy-induced neutralizing antibodies (NAbs) to interferon-beta (IFN-β) have reduced responses to IFN-β treatment, resulting in higher relapse rates, increased magnetic resonance imaging activity, and a higher risk of disease progression. A functional assay was employed for both screening and titering of IFN-β NAbs utilizing a human cell line ...
Born M - - 2012
Purpose: To compare the dose area products of pediatric VCUG in daily practice with the dramatically reduced official German diagnostic reference levels, which are based on selected data. Materials and Methods: 413 consecutive pediatric VCUG examinations were analyzed. Results: The mean dose area product of all examinations was 0.97 dGycm². ...
Figg Travis M - - 2012
A computational Hammett analysis of oxy-insertion into platinum-aryl bonds is performed. Modeled transformations involve the two-step conversion of [((X)bpy)Pt(R)(OY)](+) (R = p- or m-X-C(6)H(4); Y = 4- or 3-X-pyridine; (X)bpy = 4,4'- or 5,5'-X-bpy; X = NO(2), H, OMe, NMe(2)) proceeding through a Pt-oxo intermediate to form aryloxide [((X)bpy)Pt(OR)(Y)](+), which ...
Krüger Oliver - - 2012
Synthetic athletic tracks and turf areas for outdoor sporting grounds may release contaminants due to the chemical composition of some components. A primary example is that of zinc from re-used scrap tires (main constituent, styrene butadiene rubber, SBR) - that might be harmful to the environment. Thus methods for the ...
Guirola Ricardo - - 2012
Polyarteritis nodosa is a systemic necrotizing vasculitis involving medium-sized muscular arteries. Polyneuropathy is the only neurologic manifestation included in the pediatric classification schema. Central nervous system manifestations include infarction, hemorrhage, and encephalitis. We report on a 13-year-old female whose initial presentation of polyarteritis nodosa included hypertension, seizures, and neuroimaging findings ...
Treadwell Henrie M - - 2012
The October 2011 release of the European Commission (EC) report on the state of men's health in the European Union (EU)(1,2) focused attention on men's health around the world. It also inspired calls for a report on the state of men's health in the United States, among other regions. These ...
Iverson Ellen E Department of Pediatrics, Children's Hospital Los Angeles, California, - - 2013
We undertook this investigation to explore the manner in which surrogate decision makers for critically ill patients perceived genetic data collected in the context of clinical investigation. Surrogate decision makers for critically ill patients cared for in intensive care units of two urban hospitals participated in focus groups designed to ...
Wicha Max S - - 2012
ABSTRACT: Breast cancer metastasis accounts for the majority of deaths from this disease. In the previous issue of Breast Cancer Research, Patsialou and colleagues used a novel in vivo invasion assay to capture migrating breast cancer cells and demonstrate that the gene expression signature of these cells predicts breast cancer ...
Papakostas J C - - 2012
OBJECTIVES: To examine and compare the effects of downwards versus upwards total stripping of great saphenous vein (GSV) on saphenous nerve (SN) injury using clinical and electrophysiological studies. METHODS: Fifty patients with varicosities were equally and randomly assigned to undergo total, upwards stripping (group A) or downwards stripping (group B) ...
Rydevik Axel - - 2012
1. Selective androgen receptor modulators (SARMs) are a group of substances that have potential to be used as doping agents in sports. Being a relatively new group not available on the open market means that no reference materials are commercially available for the main metabolites. In the presented study, the in ...
Fungfuang Wirasak - - 2012
The puberty onset in mammals is tightly coupled to the animal's nutritional and metabolic state. In present study, we evaluated the effects of high fat diet on leptin, adiponectin levels, leptin mRNA expression and puberty onset in female rats. On day 21, female rats were divided into 2 groups; Normal ...
Hyun Youbong - - 2012
Mitotic inheritance of identical cellular memory is crucial for development in multicellular organisms. The cell type-specific epigenetic state should be correctly duplicated upon DNA replication to maintain cellular memory during tissue and organ development. Although a role of DNA replication machinery in maintenance of epigenetic memory has been proposed, technical ...
Zhang Wenjing - - 2012
Density functional theory (DFT) calculations have been performed to provide the first detailed computational study on the mechanism and enantioselectivity for the [4+2] cycloaddition reaction of ketenes with N-benzoyldiazenes catalyzed by N-heterocyclic carbenes (NHCs). Two possible mechanisms have been studied: first is the "ketene-first" mechanism (Mechanism A) and second is ...
Chen Song - - 2012
BACKGROUND: The aim of the present study was to assess the association between M235T polymorphism and heart failure using a meta-analysis. METHODS: A literature search of Google Scholar, PubMed, the Cochrane Library and the China National Knowledge Infrastructure database (January 1990-April 2012) was performed for relevant studies. Statistical analyses were ...
Ding Guodong - - 2012
Significant amounts of pyrethroid pesticides are used throughout China. Previous studies have suggested that exposure to pesticides may increase the risk of childhood cancer; however, few studies have focused on pyrethroid metabolites. We investigated five non-specific metabolites of pyrethroid pesticides found in children's urine and examined the correlation with childhood ...
Gautier Mathieu - - 2012
The recent development of high throughput genotyping technologies has revolutionized the collection of data in a wide range of both model and non-model species. These data generally contain huge amounts of information about the past demographic history of populations.In this study we introduce a new method to estimate divergence times ...
Corrales Teresa - - 2012
A triblock copolymer based on poly(ε-caprolactone) (PCL) and 2-(N,N-diethylamino)ethyl methacrylate (DEAEMA)/2-(methyl-7-nitrobenzofurazan)amino ethyl acrylate (NBD-NAcri), was synthesized via atom transfer radical polymerization (ATRP). The corresponding chlorohydrated copolymer, named as PCL-b-DEAEMA, was prepared and anchored via cationic exchange on montmorillonite (MMT) surface. (PCL)/layered silicate nanocomposites were prepared through melt intercalation, and XRD ...
Oliveira Daniela Cristina de - - 2012
Abstract Purpose: This longitudinal clinic study evaluated the effect of a glass ionomer sealant (GIS) and a fluoride varnish (FV) in the prevention of dental decay on newly erupted permanent molars of children with and without caries experience. Materials and methods: Eighty children, aged 6-8 years, with all four newly ...
Cui Xiao - - 2012
ABSTRACT: BACKGROUND: Male reproduction is an essential biological event in the plant life cycle separating the diploid sporophyte and haploid gametophyte generations, which involves expression of approximately 20,000 genes. The control of male reproduction is also of economic importance for plant breeding and hybrid seed production. With the advent of ...
Ford James D - - 2012
I fully agree with the points made by Macpherson and Akpinar-Elci, who note the significant vulnerabilities faced by small island nations to the health effects of climate change. Small island nations, like the indigenous populations profiled in my article, are considered to be highly vulnerable to the health effects of ...
Pérez Mayrim L - - 2012
OBJECTIVE: To describe the clinical signs, treatment, and outcomes of dogs and cats following envenomation by the eastern coral snake and to report our clinical experience with the use of Coralmyn. DESIGN: Retrospective study (1996-2011). SETTING: University teaching hospital. ANIMALS: Sixteen dogs and 4 cats with eastern coral snake envenomation. ...
Avrahami Limor L Department of Human Molecular Genetics and Biochemistry, Sackler School of Medicine, George S. Wise Faculty of Life Sciences, Tel Aviv University Tel Aviv 69978, - - 2013
Accumulation of β-amyloid (Aβ) deposits is a primary pathological feature of Alzheimer disease that is correlated with neurotoxicity and cognitive decline. The role of glycogen synthase kinase-3 (GSK-3) in Alzheimer disease pathogenesis has been debated. To study the role of GSK-3 in Aβ pathology, we used 5XFAD mice co-expressing mutated ...
Dagorn Audrey - - 2012
Gamma aminobutyric acid (GABA) is widespread in the environment and can be used by animal and plants as a communication molecule. Pseudomonas and particularly fluorescent Pseudomonas synthesize GABA and express GABA-binding proteins. In this study, we investigated the effects of GABA on the virulence of Pseudomonas aeruginosa. While exposure to ...
Jilani S Mahaboob - - 2012
Graphene oxide (GO) and graphene oxide-zinc oxide nanocomposites (GO-ZnO) were used as channel materials on SiO(2)/Si to fabricate thin-film transistors (TFT) with an aluminum source and drain. Pure GO-based TFT showed poor field-effect characteristics. However, GO-ZnO-nanocomposite-based TFT showed better field-effect performance because of the anchoring of ZnO nanostructures in the ...
Naik Ravi - - 2012
A series of (E)-phenoxyacrylic amide derivatives were synthesized and evaluated as hypoxia inducible factor (HIF) 1α inhibitors. The present structure-activity relationship study on this series identified the morpholinoethyl containing ester 4p as a potent inhibitor of HIF-1α under hypoxic conditions (IC(50) = 0.12 μM in a cell-based HRE reporter assay) ...
Jardel Nicolas - - 2012
OBJECTIVE: To report a surgical technique and long-term outcomes of type II atresia ani (AA) and rectovaginal fistula (RvF) correction, using a fistula flap technique in kittens. STUDY DESIGN: Clinical study. ANIMALS: Domestic shorthaired female kittens (n = 6) with type II AA-RvF. METHODS: Diagnosis of type II AA-RvF was ...
Shin Seung-Heon - - 2012
Bee venom (BV) has long been used as an oriental traditional medicine for the control of pain and inflammation. However, BV's anti-inflammatory mechanisms remain unclear. This study aimed to clarify the potential clinical efficacy of BV concerning the anti-inflammatory effect on nasal epithelial cell inflammation. Nasal polyp epithelial cells were ...
Wang Xin - - 2012
Hypertension control rates are unacceptably low in China. The present study demonstrates if a customized, guideline-oriented training program can cost-effectively improve hypertension management in primary healthcare. Four typical community health centers in Beijing were selected and randomized to intervention or control (one urban and one rural each). A sample of ...
Xu Xian-Rong - - 2012
Aim: The purpose of this study was to determine the effects of lutein supplement on serum cytokines, apoE and lipoprotein profiles in early atherosclerosis population.Methods: Early atherosclerosis patients (n= 65) were randomized to receive placebo (A+P, n= 31) or 20 mg/d lutein (A+L, n= 34) for 3 months.Results: Serum lutein ...
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