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Standing A J - - 2012
The factors affecting transfer of nanowire arrays from their substrates into flexible PDMS films have been systematically investigated. Experiments were carried out on gallium phosphide nanowires with a standard length of 10 μm with varying pitch (0.2-1.5 μm). The important factors were found to be penetration of the PDMS within the nanowire ...
Segal Nancy L - - 2012
A look at scientific studies of sports performance is informative in view of the 2012 Olympic games in London. The athletic life histories of selected twin competitors supplement the scientific data. Reviews of recent twin studies concerning cardiometabolic risk factors, postnatal brain maturation, parental responses to rearing triplets, and the ...
Zang Shaoyun S Department of Molecular and Cellular Pharmacology, University of Miami Miller School of Medicine, Miami, Florida 33136, - - 2013
Active zones are specialized presynaptic structures critical for neurotransmission. We show that a neuronal maintenance factor, nicotinamide mononucleotide adenylyltransferase (NMNAT), is required for maintaining active zone structural integrity in Drosophila by interacting with the active zone protein, Bruchpilot (BRP), and shielding it from activity-induced ubiquitin-proteasome-mediated degradation. NMNAT localizes to the ...
Taboada Giselle F - - 2012
The syndrome of dyskinesia associated with hyperglycemia and basal ganglia hyperintensity on T1 - weighted MR images is rare and most often affects elderly patients with type 2 diabetes. We report a case of a 79 year-old female patient who presented to the ED with a 12 h history of a left ...
Kang Jang-Won - - 2012
We report on p-type conductivity in antimony (Sb)-doped ZnO (ZnO:Sb) nanorods which have self-corrugated surfaces. The p-ZnO:Sb/n-ZnO nanorod diode shows good rectification characteristics, confirming that a p-n homojunction is formed in the ZnO nanorod diode. The low-temperature photoluminescence (PL) spectra of the ZnO:Sb nanorods reveal that the p-type conductivity in ...
Olaifa Folashade - - 2012
Experiments were performed to investigate the effect of ascorbic acid in reducing haemato-biochemical changes in pack donkeys during the cold-dry (harmattan) season. Six experimental donkeys administered orally with ascorbic acid (200 mg/kg), and six control donkeys, not administered with ascorbic acid, were subjected to packing. Blood samples were collected from ...
García-Faroldi Gianni - - 2012
Abstract Here we show that mast cells (MCs) express metalloproteases of the A disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS) family, and that ADAMTS expression is influenced by MC activation. Co-culture of MCs with live Gram-positive bacteria caused a profound induction of ADAMTS-9 and -6, as well as downregulated expression ...
Johansson Ewa - - 2012
Intake of specially processed cereal (SPC) stimulates endogenous antisecretory factor (AF) activity, and SPC intake has proven to be beneficial for a number of clinical conditions. The aim of the present study was to investigate the dosage relationship between SPC intake and plasma AF activity and to further correlate achieved ...
Barvkar Vitthal T - - 2012
Flax (Linum usitatissimum L.) seeds are an important source of food and feed due to the presence of various health promoting compounds, making it a nutritionally and economically important plant. An in-depth analysis of the proteome of developing flax seed is expected to provide significant information with respect to the ...
Canevari Thiago C - - 2012
This paper describes the development, characterization and application of an Nb(2)O(5) film formed on the surface of a carbon ceramic material, SiO(2)/C, obtained by a sol-gel method, using the spin-coating technique. The working electrode using this material will be designated as SiCNb. Hydroquinone and catechol can be oxidized at this ...
Ghosh Supratim S a Department of Cancer Biology , Wake Forest School of Medicine , Winston-Salem , NC , USA - - 2013
The simultaneous binding of netropsin in the minor groove and Zn(2+) in the major groove of a DNA hairpin that includes 10 consecutive FdU nucleotides at the 3'-terminus (3'FdU) was demonstrated based upon NMR spectroscopy, circular dichroism (CD), and computational modeling studies. The resulting Zn(2+)/netropsin: 3'FdU complex had very high ...
Kang Xiaojiao - - 2012
In this study, multifunctional poly(acrylic acid) modified lanthanide-doped GdVO(4) nanocomposites [PAA@GdVO(4): Ln(3+) (Ln = Yb/Er, Yb/Ho, Yb/Tm)] were constructed by filling PAA hydrogel into GdVO(4) hollow spheres via photoinduced polymerization. The up-conversion (UC) emission colors (green, red and blue) can be tuned by changing the codopant compositions in the matrices. ...
Keithley Richard B RB Department of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, IN 46556, - - 2013
A capillary electrophoresis system with an ultrasensitive three-color laser-induced fluorescence detector was constructed for the simultaneous measurement of glycosphingolipids conjugated with a family of BODIPY fluorophores. The compounds were separated by capillary electrophoresis and detected by laser-induced fluorescence excited within a sheath-flow cuvette. Diode-pumped solid-state lasers operating at 473 nm ...
Kapetas Leon - - 2012
Recent observations that subsurface bacteria quickly adsorb metal contaminants raise concerns that they may enhance metal transport, given the high mobility of bacteria themselves. However, metal adsorption to bacteria is also reversible, suggesting that mobility within porous medium will depend on the interplay between adsorption-desorption kinetics and thermodynamic driving forces ...
Tripathi J K - - 2012
Self-assembled α-FeSi(2) nanoislands were formed using solid-phase epitaxy of low (∼1.2 ML) and high (∼21 ML) Fe coverages onto vicinal Si(111) surfaces followed by thermal annealing. At a resulting low Fe-covered Si(111) surface, we observed in situ, by real-time scanning tunneling microscopy and surface electron diffraction, the entire sequence of Fe-silicide formation and ...
Inagaki Hideaki - - 2012
It is known that long-term post-weaning individual housing significantly reduces emissions of 22-kHz calls in male rats. In this study, we assessed post-weaning successive changes in 22-kHz calls emitted by male rats under two different types of post-weaning housing conditions (individually and socially). In addition, we evaluated the critical point ...
Clem Brian F - - 2012
The discovery of the retinoblastoma (RB-1) gene as a tumor suppressor that is disrupted in a majority of human cancers either via direct or indirect genetic alterations has resulted in increased interest in its functions and downstream effectors. Although the canonical pathway that links this tumor suppressor to human cancers ...
Wilmont Sibyl Shalo - - 2012
Passion. Courage. Altruism. These are just three of the characteristics common to transformational leaders in public health, according to Linda Fried, MD, MPH, dean of Columbia University's Mailman School of Public Health.(1) As the selection committee chairperson for The Calderone Prize in Public Health, Fried oversees the daunting task of ...
Tijtgat Pieter - - 2012
The purpose of this study was to investigate postural adjustments in one-handed ball catching. Specifically, the functional role of anticipatory postural adjustments (APA) during the initial arm raising and subsequent postural adjustments (SPA) for equilibrium control and ball-hand impact were scrutinized. Full-body kinematics and kinetics allowed an analysis of the ...
Cassio Alessandra - - 2012
Background: TSHR LOF mutations lead to a wide spectrum of phenotypes, ranging from severe congenital hypothyroidism to mild euthyroid hyperthyrotropinemia. The degree of TSH resistance depends on the severity of the impairment of the receptor function caused by the mutation and on the number of mutated alleles. Objective: In this ...
Li James J JJ Department of Psychology, University of California, Los Angeles, CA 90095, - - 2013
Emerging evidence suggests that some individuals may be simultaneously more responsive to the effects from environmental adversity and enrichment (i.e., differential susceptibility). Given that parenting behavior and a variable number tandem repeat polymorphism in the 3'untranslated region of the dopamine transporter (DAT1) gene are each independently associated with attention-deficit/hyperactivity disorder ...
Sugimori Hiroko - - 2012
Increased blood viscosity reduces blood flow and elevates vascular resistance in the cardiovascular system. The aim of this study was to elucidate how blood viscosity could affect renal function and eventually contribute to renal damage in essential hypertensives (EHT). In 164 untreated EHT without apparent renal damage (96 men, 56±12 ...
Costa Lucio G - - 2012
ABSTRACT: Lucio G. Costa is currently Professor of Environmental and Occupational Health Sciences at the School of Public Health at the University of Washington. Dr. Costa is a renowned neurotoxicologist whose research interests are focused on understanding the role of neurotoxic substances in neurodevelopmental disorders and other neurological, neuropsychiatric and ...
Arsenault Daniel J DJ Atlantic Research Centre, Department of Pediatrics and Biochemistry, Dalhousie University, Halifax, Nova Scotia B3H 4R2, - - 2013
Cancer cells have enhanced lipogenic capacity characterized by increased synthesis of fatty acids and complex lipids, including phosphatidylcholine (PC). As the rate-limiting enzyme in the CDP-choline pathway for PC synthesis, CTP:phosphocholine cytidylyltransferase α (CCTα) is implicated in the provision of membranes and bioactive lipids necessary of cell proliferation. In this ...
Irisarri Iker - - 2012
ABSTRACT: BACKGROUND: Understanding the causes underlying heterogeneity of molecular evolutionary rates among lineages is a long-standing and central question in evolutionary biology. Although several earlier studies showed that modern frogs (Neobatrachia) experienced an acceleration of mitochondrial gene substitution rates compared to non-neobatrachian relatives, no further characterization of this phenomenon was ...
Yoshida Akihito - - 2012
We report the fabrication technique and optical properties of multilayered two-dimensional (2D) gold nanoparticle sheets ('Au nanosheet'). The 2D crystalline monolayer sheet composed of Au nanoparticles shows an absorption peak originating from a localized surface plasmon resonance (LSPR). It was found that the absorption spectra dramatically change when the monolayers ...
Cray L A - - 2012
ABSTRACT Objectives: 1) Explore the variability in how symptoms clustered together over the late reproductive stage, early and late meyesausal transition (MT) stages, and early postmenopause. 2) Determine if the symptom factor structure of the preceding MT stage would predict the symptom factor structure of the MT stage immediately following ...
De Smet Sarah - - 2012
Abstract Pigs are important reservoirs for Arcobacter. Since 1978, Arcobacter species have been associated with reproduction disorders, but excretion by clinically healthy pigs has been frequently reported as well. Information on Arcobacter colonization of the porcine gastrointestinal tract is lacking. In the present study, gastrointestinal tracts of 12 pigs were ...
O'Neill S M - - 2012
Objective Arterial stiffness is an independent marker of cardiovascular risk that increases with age, hypertension, diabetes and hyperlipidemia, both for men and women (although more pronounced in women). This study was designed to establish whether menopause augments the age-dependent change. Methods The study evaluated pulse wave analysis and pulse wave ...
Hata Masaki M Department of Removable Prosthodontics, School of Dentistry, Aichi-Gakuin University, Nagoya, - - 2013
Dental pulp stem cells (DPSCs), which can differentiate into several types of cells, are subjected to mechanical stress by jaw movement and occlusal forces. In this study, we evaluated how the uniaxial mechanical stretch influences proliferation and differentiation of DPSCs. DPSCs were isolated and cultured from male Sprague-Dawley rats. Cultured ...
Houlihan Diarmaid D DD Centre for Liver Research, National Institute for Health Research Biomedical Research Unit, University of Birmingham, Birmingham, - - 2012
Platelet-derived growth factor receptor α (PDGFR-α) and stem cell antigen 1 (Sca-1) have recently been identified as selective markers of mouse mesenchymal stem cells (MSCs). PDGFR-α(+)Sca-1(+) (PαS) MSCs have augmented growth potential and robust tri-lineage differentiation compared with standard culture-selected MSCs. In addition, the selective isolation of PαS MSCs avoids ...
Mihret Adane - - 2012
The immune response against Mycobacterium tuberculosis is multifactorial, involving a network of innate and adaptive immune responses. Characterization of the immune response, a clear understanding of the dynamics and interplay of different arms of the immune response are critical to allow the development of better tools for combating tuberculosis. Dendritic ...
Havens Jennifer R - - 2013
We determined the factors associated with hepatitis C (HCV) infection among rural Appalachian drug users. This study included 394 injection drug users (IDUs) participating in a study of social networks and infectious disease risk in Appalachian Kentucky. Trained staff conducted HCV, HIV, and herpes simplex-2 virus (HSV-2) testing, and an ...
Bona Gianni - - 2012
Background: Subclinical hypothyroidism (SH) is a quite common disorder in the pediatric age group. Objective: The aim of this paper is to present a review of the studies investigating the natural course of SH and the effects of replacement therapy with levothyroxine in childhood. Methods: We systematically searched PubMed, Cochrane, ...
Wu Yingjie - - 2012
We demonstrate the first example of a self-propelled Janus polyelectrolyte multilayer hollow capsule that can serve as both autonomous motor and smart cargo. This new autonomous Janus capsule motor composing of partially coated dendritic platinum nanoparticles (Pt NPs) was fabricated by using a template-assisted layer-by-layer (LbL) self assembly combined with ...
Zhao Meng-Qiang - - 2012
The theoretically proposed graphene/single-walled carbon nanotube (G/SWCNT) hybrids by placing SWCNTs among graphene planes through covalent C-C bonding are expected to be with extraordinary physical properties and promising engineering applications. However, the G/CNT hybrids that have been fabricated differ a lot with the proposed G/SWCNT hybrids either because the covalent ...
Leung Molly M - - 2013
The Rhodobacter capsulatus response regulator CtrA controls the expression of 227 genes, some of which are upregulated by both the phosphorylated and unphosphorylated forms of CtrA. Therefore, CtrA concentration alone, regardless of phosphorylation state, may determine expression of downstream genes, yet little is known about the regulation of ctrA in ...
Thorne Leigh - - 2012
ABSTRACT: BACKGROUND: Protein misfolding cyclic amplification (PMCA) is a method that facilitates the detection of prions from many sources of transmissible spongiform encephalopathy (TSE). Sheep scrapie represents a unique diversity of prion disease agents in a range of susceptible PRNP genotypes. In this study PMCA was assessed on a range ...
Wang Z - - 2012
The purpose of this study was to determine EriB in plasma by using the method of HPLC and collect the preclinical pharmacokinetic parameters of EriB.The analysis involved a simple liquid-liquid extraction. After making alkaline with NaOH, plasma was extracted with diethyl ether and the organic extract was then evaporated. From ...
Verma Yogesh Kumar - - 2012
B Cell Lymphoma-2 (Bcl-2) protein suppresses ionizing radiation-induced apoptosis in hemato-lymphoid system. To enhance the survival of irradiated cells, we have compared the effects and mechanism of Bcl-2 and its functional variants, D34A (caspase-3 resistant) and S70E (mimics phosphorylation on S70). Bcl-2 and its mutants were transfected into hematopoietic cell ...
Marzluff William F - - 2012
The 3' ends of two large noncoding RNAs, MALAT1 (metastasis-associated lung adenocarcinoma transcript 1) and MEN β, are formed by cleavage by RNase P and are capped but not polyadenylated. In the November 1, 2012, issue of Genes & Development, Wilusz and colleagues (pp. 2392-2407) show that when these 3' ...
Oguz K K - - 2012
BACKGROUND AND PURPOSE:Studies shows ictal behavior and symptoms are affected by patient sex in temporal lobe epilepsy. The purpose of our study was to determine whether alterations in the WM as assessed by DTI display different patterns in male and female patients with unilateral HS.MATERIALS AND METHODS:Patients with unilateral HS ...
Selvakumar K - - 2012
Polychlorinated biphenyls (PCBs) comprise a ubiquitous class of toxic substances associated with carcinogenic and tumor-promoting effects as well as neurotoxic properties. Reactive oxygen species, which is produced from PCBs, alters blood-brain barrier (BBB) integrity, which is paralleled by cytoskeletal rearrangements and redistribution and disappearance of tight junction proteins (TJPs) like ...
Thomas Kristen E - - 2012
The integration of vestibular and somatosensory information for the control of lower limb musculature remains elusive. To determine whether a subthreshold vestibular input influences the cutaneous evoked response, the isometric EMG activity in the posturally inactive soleus muscles of 13 healthy, seated subjects was collected. Vestibular afferents were activated using ...
Pagano Giovanni - - 2012
Abstract An involvement of oxidative stress (OS) was found in recent studies of Sjøgren's syndrome (SS) that reported significant changes in protein oxidation, myeloperoxidase activity, TNF-α, nitrotyrosine and GSH levels in plasma from SS patients. Excess levels of OS markers, as oxidative DNA damage and propanoyl-lysine were reported in saliva ...
Ravindran V - - 2012
Monozygotic twins, 27 years old, with primary anti-phospholipid syndrome have been described. The first of the twins had obstetric morbidities (one miscarriage at 12 weeks and premature birth of a growth-restricted fetus at 27 weeks secondary to pre-eclampsia) and the second had venous thrombosis. Lupus anticoagulant was present in both ...
Mijares Eleina E Cuban Neurosciences Center, Havana, Cuba. - - 2013
Receiver operating characteristic (ROC) methodology was used to compare the performance of different statistics in the automatic detection of multiple auditory steady-state responses (MSSR) and click auditory brainstem responses (cABR). Thirty-five healthy newborns tested within the first two weeks of birth. In each case cABR and MSSR (0.5 and 2 ...
Malcolm Adam C - - 2012
A series of formal donor-acceptor adducts of aminoborane (H(2)BNH(2)) and its N-substituted analogues (H(2)BNRR') were prepared: LB-H(2)BNRR'(2)-BH(3) (LB = DMAP, IPr, IPrCH(2) and PCy(3); R and R' = H, Me or tBu; IPr = [(HCNDipp)(2)C:] and Dipp = 2,6-iPr(2)C(6)H(3)). To potentially access complexes of molecular boron nitride, LB-BN-LA (LA = ...
Julian Laura - - 2013
In the largest sample studied to date, we measured cognitive functioning in children and adolescents with pediatric multiple sclerosis (n = 187) as well as those with clinically isolated syndrome (n = 44). Participants were consecutively enrolled from six United States Pediatric Multiple Sclerosis Centers of Excellence. Participants had a ...
Campos-Rodriguez Francisco - - 2013
Obstructive sleep apnea (OSA) has been associated with increased cancer mortality, but whether it is also associated with cancer incidence is unknown. To investigate whether OSA is associated with increased cancer incidence in a large clinical cohort. A multicenter, clinical cohort study including consecutive patients investigated for suspected OSA between ...
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