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Results 401 - 450 of 1755
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Karle William E - - 2012
BACKGROUND: For patients who have extensive prior treatment, use of the internal mammary artery/vein (IMA/IMV) or cephalic vein has been shown to be a reliable option. Additionally, for those patients who require vascularized bone and extensive soft tissue reconstruction, the combined latissimus dorsi scapular free flap (mega-flap) is an excellent ...
Gage Heather - - 2012
ABSTRACT: BACKGROUND: Older people living in care homes in England have complex health needs due to a range of medical conditions, mental health needs and frailty. Despite an increasing policy expectation that professionals should operate in an integrated way across organisational boundaries, there is a lack of understanding between care ...
Anderson Craig M - - 2012
Hetero-multinuclear, platinum/ruthenium species were synthesized and tested for their effect on the motility of A549 (nonsmall cell lung) and MDA-MB-231 (breast) cancer cells and for their ability to inhibit DNA mobility using gel electrophoresis. It was found that the Ru(2)Pt trinuclear species [Na(2)]{[Ru(III)Cl(4)(DMSO-S)(-μ-pyz)](2)Pt(II)Cl(2)}, AH197, was much more efficient at inhibiting ...
Christian Parul - - 2012
BACKGROUND: Micronutrient deficiencies may be related to poor fetal growth and short gestation. Few studies have investigated the contribution of maternal vitamin A deficiency to these outcomes. OBJECTIVE: In rural northwestern Bangladesh, we examined the effects of weekly antenatal vitamin A and β-carotene supplementation on birth weight, length, circumferential body ...
Chen Pei - - 2012
Many studies have shown that pine needles are a good bio-monitor for atmospheric concentrations of polychlorinated dibenzo-p-dioxins (PCDDs) and polychlorinated dibenzofurans (PCDFs). However, this bio-monitor has not been tested in large areas, and the quantitative relationship between concentrations in pine needles and air has not been established. In the present ...
Calamante Fernando - - 2012
The thalamus is one of the most important brain structures, with strong connections between subcortical and cortical areas of the brain. Most of the incoming information to the cortex passes through the thalamus. Accurate identification of substructures of the thalamus is therefore of great importance for the understanding of human ...
Legisa Danilo - - 2012
Bluetongue (BT) is an insect-transmitted viral disease of ruminant species and represents a major barrier for international trade of animals and their products. Bluetongue virus (BTV) has a genome composed by ten linear segments of double stranded RNA (dsRNA) which codify for at least ten different viral proteins. In South ...
Welch A A - - 2012
Conservation of muscle mass is important for fall and fracture prevention but further understanding of the causes of age-related muscle loss is required. This study found a more alkaline diet was positively associated with muscle mass in women suggesting a role for dietary acid-base load in muscle loss. INTRODUCTION: Conservation ...
Vandael David H F - - 2012
Mouse chromaffin cells (MCCs) fire spontaneous action potentials (APs) at rest. Ca(v)1.3 L-type calcium channels sustain the pacemaker current, and their loss results in depolarized resting potentials (V(rest)), spike broadening, and remarkable switches into depolarization block after BayK 8644 application. A functional coupling between Ca(v)1.3 and BK channels has been ...
Huang Hongwen - - 2012
A controllable synthesis of various morphologies of CuO nanostructures with tuning by hetero-metal cations has been developed in aqueous solution at room temperature. The morphologies of CuO can be engineered from nanosheets to nanoparticles with different length ratios of the long axis to the short axis. The formation of many ...
Wrigley Benjamin J - - 2012
BACKGROUND: -Cross-talk between monocytes and platelets is reflected by the formation of monocyte-platelet aggregates (MPAs). It is not known whether MPAs are affected in heart failure (HF) and we examined differences in patients with acute HF (AHF), stable HF (SHF), stable coronary artery disease (CAD) without HF, and healthy controls ...
Blanco Sofía Teresa - - 2012
CO2 Capture and Storage (CCS) is regarded as a good strategy to mitigate the ever increasing levels of greenhouse gases in the atmosphere. The presence and type of impurities clearly influence the properties and behavior of the anthropogenic CO2, and consequently the design and operation of CCS technology facilities. Its ...
Trojan Brandon - - 2012
Objectives: To evaluate the sensitivity, specificity, and false-positive rate of the nuclear matrix protein-22 (NMP22) test in patients with end-stage renal disease (ESRD) and microscopic hematuria in order to avoid unnecessary follow-up tests for patients with false-positive NMP22 test results. Patients and Methods: Patients with ESRD were screened for microscopic ...
Posma Joram Matthias - - 2012
We describe a new multivariate statistical approach to recover metabolite structure information from multiple (1)H NMR spectra in population sample sets. SubseT Optimization by Reference Matching (STORM) was developed to select subsets of 1H NMR spectra that contain specific spectroscopic signatures of biomarkers differentiating between different human populations. STORM aims ...
Mueller Wolfgang Peter - - 2012
Neuroblastoma is an embryonic tumor of the peripheral sympathetic nervous system and is metastatic or high risk for relapse in nearly 50% of cases. Therefore, exact staging with radiological and nuclear medicine imaging methods is crucial for defining the adequate therapeutic choice. Tumor cells express the norepinephrine transporter, which makes ...
Steiner Holly L - - 2012
INTRODUCTION AND HYPOTHESIS: Physicians-in-training play a role in guiding patient care, and their contributions may improve adherence to clinical practice guidelines. However, there is scant information in the literature assessing this impact on perioperative decision-making. The purpose of this study was to determine whether involvement of urogynecology fellows results in ...
Lakeman Marielle M E - - 2012
INTRODUCTION AND HYPOTHESIS: To provide a clinical opinion based on current literature reporting on the effects of peri-operative pelvic floor muscle training (PFMT) on postoperative pelvic floor symptoms, recurrent treatment after pelvic organ prolapse (POP) surgery and current clinical practice in the Netherlands. METHODS: The PubMed database was searched, with ...
Manheimer Eric - - 2012
In a dark time, the eye begins to see. - Theodore Roethke The clouds were heavier, the air thicker. The wind picked up. The news that the subways would be shut down at 7 p.m. spread quickly by word of mouth. The streets in our Greenwich Village neighborhood were filled ...
Bhan Chandra - - 2012
There has been a growing interest in the use of protein conjugated-nanoparticles for applications in biomedical, sensing, and advanced imaging. The objective of this study was to understand the interaction of protein conjugated silver nanoparticles (Ag/BSA NPs) with biological substrate/membranes (collagen layer). The adsorption behavior of synthesized Ag/BSA NPs on ...
Ceci Francesco - - 2012
PURPOSE: To determine the diagnostic efficacy of (11)C-choline PET/CT in patients with prostate cancer (PC) after radical prostatectomy who presented with increasing PSA levels during follow-up in spite of being on hormone treatment (HT), and therefore showing HT resistance. METHODS: We evaluated a large series of 157 consecutive PC patients ...
Antic V - - 2012
Workers involved in interventional cardiology procedures receive high eye lens dose if protection is not used. Currently, there is no suitable method for routine use for the measurement of eye dose. Since most angiography machines are equipped with suitable patient dosemeters, deriving factors linking staff eye doses to the patient ...
Jensen Line Flytkjær - - 2012
ABSTRACT: BACKGROUND: A population-based breast cancer screening programme was implemented in the Central Denmark Region in 2008--09. The objective of this registry-based study was to examine the association between socio-demographic characteristics and screening participation and to examine whether the group of non-participants can be regarded as a homogeneous group of ...
Khan Rahmat Ali - - 2012
ABSTRACT: BACKGROUND: Launaea procumbens is used in the treatment of oxidative stress and mental disorders. The effects of Launaea procumbens methanolic extracts (LPMEs), i.e., 100 and 200 LPME mg/kg body weight (b.w.), on cognitive performance as well as on the activity of acetylcholinesterase, and antioxidant enzymes in rat brain tissue ...
Ilivitzki Anat - - 2012
BACKGROUND: Interim 18F-FDG PET helps predict outcome and tailor treatment in adults with Hodgkin disease (HD). OBJECTIVE: The purpose of this study was to assess predictive values of interim 18F-FDG PET/CT in children with HD and to define the potential added value to interim PET of low-dose CT. MATERIALS AND ...
Krijthe Bouwe P - - 2012
Background: High plasma dehydroepiandrosterone sulfate (DHEAS) levels have been associated with a reduced risk of cardiovascular disease and atherosclerosis. To our knowledge, no previous follow-up study has investigated the association between DHEAS and the development of atrial fibrillation. Our objective was to investigate the association between DHEAS levels and incident ...
Moodie Crawford - - 2012
In a growing number of countries tobacco companies are severely restricted in how they can legally market their products. In these 'dark' markets the role of packaging as a promotional and communications tool becomes more pronounced. How packaging is used for the most expensive cigarette brands in dark markets has ...
Jangi Sushrut - - 2012
Around 9 p.m. on October 29, 2012, the bright lights at Manhattan's Beth Israel Medical Center flickered and went out. Dr. Harris Nagler, hospital president, stepped out onto 16th Street to find every building around him in shadow. "I remember feeling a kind of awe," he says, "that despite all ...
Müsseler Jochen - - 2012
Previous studies have shown that the localization of the perceived onset position of a moving target varies with the trial context. When the moving target appeared at predictable positions to the left or right of fixation (constant context), localization judgments of the perceived onset positions were essentially displaced in motion ...
Enmi Jun-Ichiro - - 2012
In dynamic susceptibility contrast-enhanced magnetic resonance imaging (DSC-MRI), an arterial input function (AIF) is usually obtained from a time-concentration curve (TCC) of the cerebral artery. This study was aimed at developing an alternative technique for reconstructing AIF from TCCs of multiple brain regions. AIF was formulated by a multi-exponential function ...
Diamantopoulos Athanasios - - 2012
PURPOSE: Application of metal stents is complicated by neointimal hyperplasia leading to vessel restenosis and reocclusion. Treatment options in cases presenting with complete occlusion of the stented segment and recurrent critical limb ischemia (CLI) are limited. We present the option of the subintimal/substent technique in dealing with occluded stents. METHODS: ...
Cahill J - - 2012
ACCESSIBLE SUMMARY: A group of four mental health nurses were trained to deliver and evaluate psychodynamic interpersonal therapy, an evidence-based model of therapy, in a University research setting. We were able to compare data with a group of cognitive behavioural therapists in the same University setting, enabling us to replicate ...
Bodin M - - 2012
There are concerns that anthropogenic harvesting may cause phenotypic adaptive changes in exploited wild populations, in particular maturation at a smaller size and younger age. In this paper, we study the evolutionarily stable size at maturation of prey subjected to size-selective harvesting in a simple predator-prey model, taking into account ...
Wang Yimin - - 2012
We report ab initio potential energy and dipole moment surfaces that span the regions describing the minima of trans and cis-HOCO and the barrier separating them. We use the new potential in three types of variational calculations of the vibrational eigenstates, for zero total angular momentum. Two use the code ...
Shan Aiqin - - 2012
Objective: To investigate the expression and clinical significance of both matrix metalloproteinase-2 (MMP-2) and its tissue inhibitor (tissue inhibitor of metalloproteinase-2 (TIMP-2)) in tunica media of radial artery in uremic patients. Methods: The modified radial arteries from 80 uremic patients during internal arteriovenous fistula surgery were selected and used as ...
Lu Dahua - - 2012
The CA3 area serves a key relay on the tri-synaptic loop of the hippocampal formation which supports multiple forms of mnemonic processing, especially spatial learning and memory. To date, morphometric data about human CA3 pyramidal neurons are relatively rare, with little information available for their pre- and postnatal development. Herein, ...
Rosengren Bert-Inge - - 2012
In peritoneal dialysis (PD) patients, the frequent exposure to "unphysiologic" dialysis fluids elicits a chronic state of a low-grade peritoneal inflammation leading to interstitial matrix remodeling and angiogenesis. Proinflammatory cytokines are important regulators involved in this inflammatory process that ultimately leads to dysfunction of the peritoneum as a dialysis membrane. ...
Layec Sabrina - - 2012
BACKGROUND: Segmental reversal of the small bowel (SRSB) is proposed in patients with short-bowel syndrome (SBS) as a rehabilitative therapy, but its effects on absorption have not been studied. OBJECTIVE: We aimed to determine intestinal macronutrient absorption and home parenteral nutrition (HPN) dependence in SBS patients with intestinal failure. DESIGN: ...
Sun Yu - - 2012
PURPOSE: The purpose of this study was to assess the diagnostic performance of breast-specific gamma imaging (BSGI) as an adjunct modality to mammography for detecting breast cancer. METHODS: Comprehensive searches of MEDLINE (1984 to August 2012) and EMBASE (1994 to August 2012) were performed. A summary receiver operating characteristic curve ...
Chen Jie - - 2012
Objective: To detect genetic cause of two Chinese siblings (patient 1 and 2) with Pendred syndrome. Design: Patients and their parents underwent clinical and genetic evaluations. To identify genetic mutations, sequencing of SLC26A4 was carried out. Study sample: Two siblings and their parents. Results: Clinical evaluations showed that patient 1 ...
Yang Wen-Chi - - 2012
ABSTRACT Several molecular markers, such as NPM1, FLT3, and CEBPA, have been incorporated into both the World Health Organization and European Leukemia Net classifications as routine assessments for the diagnosis and evaluation of prognostic significance in acute myeloid leukemia (AML). Lipocalin 2 (LCN2) is related to cancer development and is ...
Gouse Hetta - - 2012
Few studies address the extent to which, during the process of litigation, individuals with moderate-to-severe traumatic brain injury might malinger in their performance on neuropsychological assessment batteries. This study explored whether financial settlement influenced neuropsychological test performance and activities of daily living in litigants (N = 31) who were tested ...
de Jong Sonja W - - 2012
Sporadic ALS is a multifactorial disease for which there are probably multiple genetic risk factors. An association with increased parental age might suggest there is a role for specific (epi)genetic changes. Previous studies have shown conflicting results on the association between parental age and the risk of ALS. A large, ...
Arap Marco Antonio - - 2012
Abstract Objective. The aim of this study was to report on the safety and efficacy of 90 consecutive laparoscopic pyeloplasties carried out in a university hospital. Material and methods. The outcomes of 90 transperitoneal dismembered pyeloplasties that were performed by residents at the hospital from March 2004 to March 2010 ...
Zhang Hong-Mei - - 2012
Protein kinase Cα (PKCα) has been implicated in the regulation of a variety of cellular functions, such as proliferation, differentiation, and apoptosis, in response to a diverse range of stimuli. Activated PKCα mediates oxidative stress, apoptosis, and inflammatory reaction. Thyroid hormone (TH) is essential for the proper development of the ...
Koo Jasung - - 2012
We demonstrate the feasibility of mapping a sentinel lymph node (SLN) and urinary bladder by using modified single-walled carbon nanotubes (SWNTs) as a nonionizing photoacoustic (PA) contrast agent. To improve the PA sensitivity, indocyanine green (ICG) was conjugated with SWNTs and the optical absorption of SWNTs-ICG was enhanced by approximately ...
La Joie Renaud - - 2012
Gray matter atrophy, glucose hypometabolism, and β-amyloid Aβ deposition are well-described hallmarks of Alzheimer's disease, but their relationships are poorly understood. The present study aims to compare the local levels of these three alterations in humans with Alzheimer's disease. Structural magnetic resonance imaging, (18)F-fluorodeoxyglucose positron emission tomography (PET), and (18)F-florbetapir ...
Sainsbury Sarah - - 2012
The general transcription factor (TF) IIB is required for RNA polymerase (Pol) II initiation and extends with its B-reader element into the Pol II active centre cleft. Low-resolution structures of the Pol II-TFIIB complex indicated how TFIIB functions in DNA recruitment, but they lacked nucleic acids and half of the ...
Seki Masafumi - - 2012
Prothrombin (Factor II, FII) deficiency is an extremely rare autosomal recessive condition with an estimated incidence of 1:2 million. As severe and life-threatening bleeding is rare in FII deficiency, on demand therapy with administration of prothrombin complex concentrates (PCCs) or fresh frozen plasma is generally performed, and prophylactic therapy for ...
Pan Aihua - - 2012
Epidural hematoma (EDH) is a type of life-threatening traumatic brain injury. Little is known about the extent to which EDH may cause neural damage and regenerative response in the cerebral cortex. Here we attempted to explore these issues by using guinea pigs as an experimental model. Unilateral EDH was induced ...
Owusu James A - - 2012
ObjectiveTo analyze the incidence of postparotidectomy facial nerve dysfunction in pediatric patients and to evaluate the association between patient demographics or underlying pathology and functional outcomes.Study DesignCase series with chart review.SettingTertiary-care pediatric hospital.Subjects and MethodsWe reviewed charts of patients younger than 18 years who underwent parotidectomy performed by a pediatric ...
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