Search Results
Results 501 - 550 of 2028
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Pastukhov Alexander - - 2012
In the structure-from-motion paradigm, physical motion on a screen produces the vivid illusion of an object rotating in depth. Here, we show how to dissociate illusory depth and illusory rotation in a structure-from-motion stimulus using a rotationally asymmetric shape and reversals of physical motion. Reversals of physical motion create a ...
Sakata Kenji - - 2012
BACKGROUND: EXAGGERATED NEOINTIMAL HYPERPLASIA IS CONSIDERED AS THE PRIMARY MECHANISM FOR INCREASED RESTENOSIS IN PATIENTS WITH DIABETES MELLITUS (DM) TREATED WITH BARE-METAL STENT. HOWEVER, THE VESSEL RESPONSE IN DM AND NON-DM TREATED WITH DIFFERENT DRUG-ELUTING STENTS (DES) HAS NOT BEEN SYSTEMATICALLY EVALUATED.METHODS AND RESULTS: WE INVESTIGATED 3D INTRAVASCULAR ULTRASOUND (POSTPROCEDURE ...
Heljo Ville P - - 2012
Melibiose monohydrate has shown promise when employed as a pharmaceutical excipient, but its physical properties have not been adequately characterized. Therefore, two different melibiose monohydrate batches were analyzed as received or after storage under different relative humidity (RH) atmospheres. The particle size distributions and specific surface areas of the two ...
Swillens Abigail - - 2012
In the search for better predictors of cardiovascular events, pulse wave velocity (PWV) has gained considerable interest. We compared three single-location methods to locally estimate PWV based on simultaneous measurements of pressure (P), velocity (U) or arterial diameter (D): the PU, ln(D)U and QA-method. First, the performance of these methods ...
Yang Yanou - - 2012
Certain functional groups/structural motifs are known to generate chemically reactive metabolites that can covalently modify essential cellular macromolecules, and therefore have the potential to disrupt biological function and elicit idiosyncratic adverse drug reactions. In this report, we describe the bioactivation of 5-substituted 2-(alkylthio)-1, 3, 4 thiadiazoles and 2-(alkylthio)-1, 3-benzothiazoles, which ...
Divito Michael D - - 2012
PURPOSE: TO INVESTIGATE COMPOSITIONS OF SILICA-COLLAGEN HYBRID MATERIALS AS POTENTIAL ARTIFICIAL CORNEAL SUBSTITUTES, AND HOW THESE COMPONENTS AFFECT THE OPTICAL AND BIOMECHANICAL PROPERTIES OF THE HYBRIDS, AND THEIR BIOCOMPATIBILITY IN AN ORGAN CULTURE MODEL. METHODS: Hybrid materials were created from different proportions of collagen and silica precursors, and manufactured to ...
Millán Alba - - 2012
A versatile Ti/Ni multimetallic protocol is described for the efficient catalysis of two different reactions, namely a Heck- and reductive-type cyclization of alkyl iodides, in the absence or presence of water, respectively. Noteworthy, the versatility of Ti(III) chemistry allows an oxidative ending step under reductive conditions to give Heck-type products, ...
McGhie David - - 2012
BACKGROUND:Excessive repetitive loads are widely believed to be the cause of overload or overuse injuries. On third-generation artificial turf, impacts have been found to vary with surface and shoe properties. Mechanical devices are considered not representative for measuring impact absorption during athletic movements, and pressure insoles have been shown as ...
Kong Yun - - 2012
This study is aimed at controlling eutrophication through converting the nutrients such as nitrogen and phosphorus into microbial protein and simultaneously inhibiting the growth of Microcystis aeruginosa by Candida utilis. C. utilis and M. aeruginosa (initial cell density was 2.25 × 10(7) and 4.15 × 10(7) cells·mL(-1)) were cultured together in the absence or ...
Ikeuchi Kazutada - - 2012
Asymmetric bromolactonization of prochiral cyclohexadiene derivatives with N-bromosuccimide proceeded in the presence of (DHQD)(2)PHAL as a chiral catalyst to afford the corresponding bromolactones with up to 93% ee. This reaction was also applicable to the kinetic resolution of a racemic cyclic ene-carboxylic acid, where the starting material was recovered with ...
Emmeline Yeo Pei Shan - - 2012
Using a combination of accurate density-functional theory and a nonequilibrium Green's function method, we calculate the ballistic thermal conductance characteristics of tensile-strained armchair (AGNR) and zigzag (ZGNR) edge graphene nanoribbons, with widths between 3 and 50 Å. The optimized lateral lattice constants for AGNRs of different widths display a three-family behavior ...
Carpentier Nicolas - - 2012
The adherence to medication in drug-resistant focal epilepsy (RFE) remains largely unknown. The present work aimed to assess the frequency of recent adherence to antiepileptic drugs (AEDs) in patients with RFE. This prospective observational study screened all patients with RFE, admitted to the Nancy University Hospital between April 2006 and ...
Gobbo João Paulo - - 2012
The photophysics of 8-azaadenine (8-AA) has been studied with the CASPT2//CASSCF protocol and ANO-L double-ζ basis sets. Stationary equilibrium structures, surface crossings, minimum energy paths and linear interpolations have been used to study possible mechanisms to populate the lowest triplet state, T(1) (3)(ππ(*)), capable of sensitizing molecular oxygen. Our results ...
Drake G - - 2012
BACKGROUND: Moodscope is an entirely service-user-developed online mood-tracking and feedback tool with built-in social support, designed to stabilize and improve mood. Many free internet tools are available with no assessment of acceptability, validity or usefulness. This study provides an exemplar for future assessments. Method A mixed-methods approach was used. Participants ...
Lölsberg Wibke - - 2012
A short and enantioselective total synthesis of helioporins C and E, which are bioactive marine diterpenes containing a serrulatane or amphilectane skeleton, was elaborated. The chirogenic step, i.e. a Cu(I)-catalyzed allylic alkylation of a cinnamyl chloride with methylmagnesium bromide, proceeded with virtually complete enantioselectivity (99% ee) in the presence of ...
Zhu Haiming - - 2012
Recent reports of multiexciton generation (MEG), a process by which one absorbed photon generates multiple excitons, in lead chalcogenide nanocrystals (NCs) have intensified research interest in using this phenomenon to improve the efficiency of solar energy conversion. Practical implementation of MEG processes in solar cells and solar-to-fuel conversion devices requires ...
Wu Hai-Hong - - 2012
The heterometallic appended {MMn(III)(4)} (M = Dy(3+) and K(+)) cubanes were firstly trapped by two diamagnetic POM shells, which were robust enough to construct inorganic crystalline tubular materials. Magnetic study reveals the presence of a SMM-like slow magnetic relaxation feature in the heterometallic cluster-containing POM.
Hatam Gholam Reza - - 2012
Leishmania tropica is one of the main etiological agents of cutaneous leishmaniasis in Iran. For ultrastructural and isoenzyme study, axenic amastigotes were cultured in a brain-heart infusion medium containing 20 % fetal calf serum, pH 4.5, and incubated at 37 °C in 5 % CO(2). Different stages of L. tropica revealed the same isoenzyme ...
Kunte Hagen - - 2012
A 62-year-old man was admitted after recurrent transient left-sided weakness and sensory loss. Ultrasound (US) examination revealed a 70% narrowing of the right proximal internal carotid artery (ICA). Contrast-enhanced US suggested plaque neovascularization (figure, A). Carotid endarterectomy of the right ICA was performed. Immunohistochemistry of the specimen showed, corresponding to ...
Yamashiro Tsuneo - - 2012
We report a case of ileal internal hernia through the foramen of Winslow into the lesser sac. Preoperative computed tomography (CT) demonstrated that the herniated ileum, which showed a closed-loop obstruction, was located behind the portal vein, and the vein was subsequently compressed and narrowed by the herniated ileum. We ...
Malone K M - - 2012
Aims. Youth and young adult suicide has increasingly appeared on international vital statistics as a rising trend of concern in age-specific mortality over the past 50 years. The reporting of suicide deaths in 5-year age bands, which has been the international convention to date, may mask a greater understanding of ...
Wakefield Alison M - - 2012
Bcl3 is a putative proto-oncogene deregulated in hematopoietic and solid tumours. Studies in cell lines suggest that its oncogenic effects are mediated through the induction of proliferation and inhibition of cell death, yet its role in endogenous solid tumours has not been established. Here we address the oncogenic effect of ...
Kirchhoff Chlodwig - - 2012
ABSTRACT: BACKGROUND: Age-dependent trabecular changes of the humeral head might weaken the fixation of suture anchors used for rotator cuff (RC) repair. This might lead to suture anchor loosening and thus compromise the integrity of the repair. The aim of this study was to analyze whether the trabecular microstructure within ...
Zhang Liguo - - 2012
DNA methylation and histone H3 Lys 9 dimethylation (H3K9me2) are important epigenetic repression marks for silencing transposons in heterochromatin and for regulating gene expression. However, the mechanistic relationship to other repressive marks, such as histone H3 Lys 27 trimethylation (H3K27me3) is unclear. FERTILIZATION-INDEPENDENT ENDOSPERM1 (FIE1) encodes an Esc-like core component ...
Mansfield Aaron S - - 2012
As macrophages are some of the first cells to encounter metastatic tumor cells in sentinel lymph nodes (SLN) and natural killer (NK) cells are critical to the cytotoxicity of abnormal cells, we sought to determine if these cell populations were altered in the presence of nodal metastasis. We used immunohistochemistry ...
Knight-Madden Jennifer M - - 2012
PURPOSE: Sickle cell disease (SCD) patients with asthma have an increased risk of death. Acute chest syndrome (ACS) is a major cause of mortality in patients with SCD, and ACS may be more common in SCD patients who smoke. The purpose of this study was to test the hypothesis that ...
Laforest Laurent - - 2012
Tiotropium is an innovative intervention in chronic obstructive pulmonary disease (COPD). Early adherence to tiotropium remains inadequately explored, notably time from initiation to discontinuation (persistence). In patients with COPD, the factors associated with the risk of discontinuing the treatment with tiotropium within 12 months following initiation were identified (12-month persistence). ...
Gaudio Pasquale Del - - 2012
In this study, a novel preparation method for alginate-based aerogels charged with nonsteroidal anti-inflammatory drugs (NSAIDs) was developed using prilling in combination with supercritical fluid technique. Nanoporous carriers were prepared by laminar jet breakup of drug/alginate solutions or suspensions followed by cross-linking in ethanol or aqueous CaCl(2) solutions, water replacement, ...
Gu Xun Wendy - - 2012
We report the synthesis, mechanical properties and deformation mechanisms of polycrystalline, platinum nanocylinders of grain size d=12nm. The number of grains across the diameter, D/d, was varied from 5 to 80 and 1.5 to 5 in the experiments and molecular dynamics simulations, respectively. An abrupt weakening is observed at a ...
Kolesnikova Tatyana D - - 2012
Drosophila SUUR (Suppressor of UnderReplication) protein was shown to regulate the DNA replication elongation process in endocycling cells. This protein is also known to be the component of silent chromatin in polyploid and diploid cells. To mark the different cell cycle stages, we used immunostaining patterns of PCNA, the main ...
Lindkvist Björn - - 2012
PURPOSE: Little is known about the association between the metabolic syndrome (MetS) and the risk of gastric adenocarcinoma. The aim of this study was to investigate whether metabolic risk factors, together or combined, were associated with the risk of gastric adenocarcinoma. METHODS: The Metabolic Syndrome and Cancer Project (Me-Can) is ...
Wang Jianpu - - 2012
Spintronics based on organic semiconductor materials is attractive because of its rich fundamental physics and potential for device applications. Manipulating spins is obviously important for spintronics, and is usually achieved by using magnetic electrodes. Here we show a new approach where spin populations can be controlled primarily by energetics rather ...
Inano Sachiko - - 2012
PURPOSE: To investigate age-related differences, gender differences, and age-by-gender interactions on the volumes of 18 neuroanatomical structures, with a large sample at a single institution. MATERIALS AND METHODS: A total of 861 normal subjects (mean age = 56.1 ± 9.8 years, age range = 24.0-84.8 years) were included in this ...
Chuang Chun-Ju - - 2012
A molecular cage based [2]rotaxane is reported in which the linear thread component can be elongated and contracted in a stepwise manner, mimicking a two-stage retractable cable that can be operated in both push-button (free-selection) and rotary (continuous-change) modes, depending on the choice of reagents.
Kim Hoe Joon - - 2012
We report a wear-resistant ultrananocrystalline (UNCD) diamond tip integrated onto a heated atomic force microscope (AFM) cantilever and UNCD tips integrated into arrays of heated AFM cantilevers. The UNCD tips are batch-fabricated and have apex radii of approximately 10 nm and heights up to 7 μm. The solid-state heater can reach temperatures ...
Jagadeesan Jagajeevan - - 2012
ABSTRACT: BACKGROUND: Most soft-tissue tumors are clinically palpable; however, some can be impalpable to clinical examination making it difficult to plan surgical management. METHODS: We present a simple method of perioperative tumor localization using a portable ultrasonography machine. RESULTS: We used the technique for seven cases, on each occasion identifying ...
Redova Martina - - 2012
Renal cell carcinoma (RCC) is the most common neoplasm of adult kidney accounting for about 3 % of adult malignancies. MicroRNAs (miRNAs) are a class of naturally occurring, short non-coding RNAs that regulate gene expression at the post-transcriptional level. We determined global miRNA expression profiles of RCC and parallel renal parenchyma ...
Lyons N A - - 2012
SUMMARY A randomized control trial on verocytotoxigenic Escherichia coli (VTEC)-infected farms found evidence that: (1) keeping animals in the same group; (2) maintaining dry bedding; (3) preventing direct contact with neighbouring cattle; and (4) maintaining a closed herd, were associated with a reduced risk of infection in youngstock aged 3-18 ...
Tang Gui-Hua - - 2012
Two new degraded diterpenoids, trigohowilols A (1) and B (2), four new heterodimers, trigohowilols C-F (3-6), one new homodimer, trigohowilol G (7), and three known degraded diterpenoids (8-10) were isolated from the methanol extract of the stems of Trigonostemon howii. Compounds 1-7 were evaluated for their cytotoxic activity against five ...
Mantarro Stefania - - 2012
ABSTRACT: BACKGROUND: An increased risk of venous thromboembolism has been reported in patients treated with non-steroidal anti-inflammatory drugs (NSAIDs). We describe a case of acute portal vein thrombosis (PVT) in a hepatitis C virus (HCV)-positive elderly patient following administration of indomethacin. CASE PRESENTATION: A 79-year-old HCV-positive man was hospitalized for ...
Oehme Daniel P - - 2012
X-ray crystallography studies have identified that most cyclic inhibitors of HIV protease (including cyclic ureas) bind in a symmetric manner, however some cyclic inhibitors, such as cyclic sulfamides, bind in a non-symmetric manner. This raises the question as to whether it is possible for cyclic sulfamides to bind symmetrically and ...
Cadzow Renee B - - 2012
PurposeThe purpose of this study was to evaluate a community-based diabetes education pilot project. The Neighborhood Health Talker project aimed to train and implement cultural health brokers primarily targeting communities of color to improve community members' diabetes knowledge and diabetes self-management skills. A secondary aim was to establish diabetes resource ...
Didiot Marie-Cecile - - 2012
Translation initiation is a fine-tuned process that plays a critical role in tumorigenesis. The use of small molecules that modulate mRNA translation provides tool compounds to explore the mechanism of translational initiation and to further validate protein synthesis as a potential pharmaceutical target for cancer therapeutics. This report describes the ...
Smits Marianne - - 2012
Photocatalytic soot oxidation is studied on P25 TiO(2) as an important model reaction for self-cleaning processes by means of electron paramagnetic resonance (EPR) and Fourier transform infrared (FTIR) spectroscopy. Contacting of carbon black with P25 leads on the one hand to a reduction of the local dioxygen concentration in the ...
Knott Brandon C - - 2012
Methane hydrates are ice-like inclusion compounds with importance to the oil and natural gas industry, global climate change, and gas transportation and storage. The molecular mechanism by which these compounds form at conditions relevant to industry and nature remains mysterious. To understand the mechanism of methane hydrate nucleation from supersaturated ...
Boivin Andrée-Anne - - 2012
The immunosuppressive drug tacrolimus requires strict therapeutic monitoring due to its narrow therapeutic index and high interindividual variability. Organic anion transporting polypeptide 1B3 (OATP1B3) is a human hepatocyte transporter involved in the hepatobiliary elimination of diverse endogenous and exogenous substances. Genetic variations within the solute carrier (SLCO) 1B3 gene that ...
Cucchiarini Magali - - 2012
Direct gene transfer strategies are of promising value to treat articular cartilage defects. Here, we tested the ability of a recombinant adeno-associated virus (rAAV) SOX9 vector to enhance the repair of cartilage lesions in vivo. The candidate construct was provided to osteochondral defects in rabbit knee joints vis-à-vis control (lacZ) ...
Okuda Shujiro - - 2012
Microbial ecologists have investigated roles of species richness and diversity in a wide variety of ecosystems. Recently, metagenomics have been developed to measure functions in ecosystems, but this approach is cost-intensive. Here we describe a novel method for the rapid and efficient reconstruction of a virtual metagenome in environmental microbial ...
Patterson Sherri L - - 2012
BACKGROUND:Cancer has traditionally been considered a single disease, but it is now known to be far more complex, with an unfolding etiology. In less than 2 centuries, hundreds-if not thousands-of drugs for the treatment of cancer and for palliative care have been developed and tested, with 143 having achieved approval ...
Scheitz Cornelia Johanna Franziska - - 2012
The transcription factor Runx1 has been studied in leukemia and blood for decades, but recently it has been also implicated in epithelial biology and pathology. Particularly in mouse skin Runx1 modulates Wnt signaling levels thereby regulating timely induction of hair follicle specification, proper maturation of the emerging adult hair follicle ...
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