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Krieter Detlef H - - 2012
The estrogenic endocrine-disrupting substance bisphenol A (BPA) is extensively used as a starting material for a variety of consumer plastic products including dialyzer materials. The present study was performed to explore plasma BPA levels in patients with impaired renal function and to investigate if dialyzers differing in elutable BPA influence ...
Sinclair Lisa Bundara - - 2012
This article describes use of the International Classification of Functioning, Disability and Health (ICF) as a tool for strategic planning. The ICF is the international classification system for factors that influence health, including Body Structures, Body Functions, Activities and Participation and Environmental Factors. An overview of strategic planning and the ...
Starbuck Eric S - - 2012
Please cite this paper as: Starbuck et al (2012) Are we prepared to help low-resource communities cope with a severe influenza pandemic? Influenza and Other Respiratory Viruses DOI: 10.1111/irv.12040. Recent research involving lab-modified H5N1 influenza viruses with increased transmissibility and the ongoing evolution of the virus in nature should remind us ...
Ayaki Masahiko - - 2012
Abstract Background: Gait speed and sleep quality are the health indices related to longevity and mortality. In the present study, we measured sleep quality, quality of life, gait speed, and visual acuity before and after cataract surgery to evaluate the efficacy of the procedure on systemic health. Methods: The study ...
Biagianti Bruno - - 2012
OBJECTIVE: Orbitofrontal cortex (OFC) dysfunction and poor decision making have been described in patients with chronic migraine and medication overuse. These neurobiological underpinnings might explain dependency-like behaviors often described in this condition, such as loss of control over painkillers, high rates of relapse after detoxification, and compromised social functioning. We ...
Kristensen Lars Erik - - 2012
OBJECTIVE: To study long-term work disability before and after tumour necrosis factor (TNF)-antagonist therapy in patients with psoriatic arthritis (PsA). METHODS: Using the population-based South Swedish Arthritis Treatment Group Register, we identified 191 patients with PsA (median age 43 years, range 18-58 years, 54% men), who between January 2003 and ...
Farhangi Mahdieh Abbasalizad - - 2012
BACKGROUND: High-dose vitamin A influences glucose and lipid profile; however, the possible effects of moderate doses (25,000 IU/d) are conflicting. We aimed to compare the effect of vitamin A supplementation on several anthropometric and biochemical variables between obese and non-obese women. METHODS: This study was performed on 84 women among ...
Chen Mei-Sha - - 2012
The differences in the C-terminal domains of human amylin peptide variants initiate different aggregation processes and differences in the composition of the aggregates by affecting the hydrophobic cores, conformations, and intra-sheet interactions of the peptides, which have distinct effects on the cytotoxicity of the peptides.
Demers Hendrix - - 2012
The Monte Carlo software CASINO has been expanded with new modules for the simulation of complex beam scanning patterns, for the simulation of cathodoluminescence (CL), and for the calculation of electron energy deposition in subregions of a three-dimensional (3D) volume. Two examples are presented of the application of these new ...
Ginn Jennifer A - - 2012
A 4 yr old spayed female Labrador retriever was examined 4 hr after ingesting an overdose of phenylpropanolamine (PPA). Clinical signs included anxiety, piloerection, mucosal ulceration, cardiac arrhythmia, mydriasis, and hyphema. Clinicopathologic abnormalities included elevated creatine kinase (CK) and aspartate aminotransferase (AST), proteinuria, and pigmenturia. Ventricular tachycardia and severe systemic ...
Kwon Eilhann - - 2012
The thermal degradation of tires under various oxygen concentrations (7-30%/Bal. N2) was investigated thermo-gravimetrically at 10˚C min-1 heating rate over a temperature range from ambient to 1000˚C. Significant mass loss (~55%) was observed at the temperature of 300-500˚C, where the thermal degradation rate was almost identical and independent on oxygen ...
Smith Craig R - - 2012
The American Association for Thoracic Surgeons (AATS) is a small, selective organization focused on scholarship in thoracic surgery, complementing the Society of Thoracic Surgeon's focus on practice issues impacting all practicing surgeons. AATS works to improve the academic quality of North American and International meetings and symposia and focuses specific ...
Müllner Elisabeth - - 2012
SCOPE: Type 2 diabetes is a multifactorial disease associated with increased oxidative stress, which may lead to increased DNA damage. The aim of this study was to investigate the effect of a healthy diet on DNA oxidation in diabetics and nondiabetics. METHODS AND RESULTS: Seventy-six diabetic and 21 nondiabetic individuals ...
Geary Laina M - - 2012
Under the conditions of ruthenium-catalyzed transfer hydrogenation employing isopropanol as a source of hydrogen, isopropoxy-substituted enyne 1 b and aldehydes 3 a-3 l engage in reductive coupling to provide products of propargylation 4 a-4 l with good to complete levels of anti-diastereoselectivity. The unprotected tertiary hydroxy moiety of isopropoxy enyne 1 b is required to enforce ...
Lohiniva Anna-Leena - - 2012
Please cite this paper as: Lohiniva et al. (2012) Poultry rearing and slaughtering practices in rural Egypt: an exploration of risk factors for H5N1 virus human transmission. Influenza and Other Respiratory Viruses DOI: 10.1111/irv.12023. Background  Highly pathogenic avian influenza (H5N1) virus continues to cause infections in Egypt. This study describes the ...
Calvitti Maurizio - - 2012
ABSTRACT: BACKGROUND: Cytoplasmic incompatibility (CI) is induced in nature by Wolbachia bacteria, resulting in conditional male sterility. Previous research demonstrated that the two Wolbachia strains (wAlbA and wAlbB) that naturally co-infect the disease vector mosquito Aedes albopictus (Asian tiger mosquito) can be replaced with the wPip Wolbachia strain from Culex ...
Corre Jean-Philippe - - 2012
Background. Germination is a key step for successful B. anthracis colonisation and systemic dissemination. Few data are available on spore germination in vivo, and necessity of spore-host-cell interactions to initiate germination is unclear.Methods. To investigate the early interactions between B. anthracis spores and the cutaneous tissue, spores were inoculated in an intraperitoneal ...
Borin-Crivellenti S - - 2012
OBJECTIVE: To investigate the feasibility and validity of sampling blood from the carpal pad in hospitalised healthy and diabetic dogs. METHODS: The carpal pad was compared to the ear as a sampling site in 60 dogs (30 healthy and 30 diabetic dogs). RESULTS: Lancing the pads was very well tolerated. ...
Tamada Tsutomu - - 2012
PURPOSE: To establish a simple method to evaluate the degree of liver parenchymal enhancement in the hepatobiliary phase (HP) of gadoxetic acid-enhanced magnetic resonance imaging (MRI). MATERIALS AND METHODS: Subjects comprised 75 patients with or without chronic liver disease who underwent gadoxetic acid-enhanced MRI and indocyanine green retention at 15 ...
Estevez-Garcia Purificacion - - 2012
ABSTRACT: BACKGROUND: Angiogenesis plays an essential role in tumor growth and metastasis, and is a major target in cancer therapy. VEGFR and PDGFR are key players involved in this process. The purpose of this study was to assess the incidence of genetic variants in these receptors and its potential clinical ...
Fan Jianquan - - 2012
In this study, an novel amphiphilic block copolymer P[(DEMA-co-APMA)- b-PEGMA]-FA and its crosslinker Uracil-(CH2)6-Uracil (U-(CH2)6-U) were synthesized and used as the targeted and pH-responsive nano-carriers for anticancer drug delivery. The hydrophobic block of the copolymer contains adenine (A) and tertiary amine moieties and the hydrophilic block is terminated with a ...
Gemma Sandra - - 2012
The intramolecular hydrogen bond formed between a protonated amine and a neighbouring H-bond acceptor group in the side chain of amodiaquine and isoquine is thought to play an important role in their antimalarial activities. Here we describe isoquine-based compounds in which the intramolecular H-bond is mimicked by a methylene linker. ...
Pubill-Ulldemolins Cristina - - 2012
The use of phosphines to assist the organocatalytic β-boration reaction of α,β-unsaturated carbonyl compounds has been demonstrated with a selected number of substrates. The new method eludes the use of Brönsted bases to promote the catalytic active species and PR(3) becomes essential to interact with the substrate resulting in the ...
Moe S Jannicke - - 2012
Increased temperature and other environmental effects of global climate change (GCC) have documented impacts on many species (e.g., polar bears, amphibians, coral reefs) as well as on ecosystem processes and species interactions (e.g., the timing of predator-prey interactions). A challenge for ecotoxicologists is to predict how joint effects of climatic ...
Griffin Kevin L - - 2012
In 1953 Sir Hans Krebs won the Nobel prize for his classic work elucidating the metabolic steps by which citrate is metabolized within the mitochondria and drives energy recovery from stored carbohydrates. Through an elegant series of reactions fed from a common substrate, the tricarboxylic acid cycle (TCA) creates carbon ...
Henning Marcus A - - 2012
Background: There is ample evidence to suggest that academic dishonesty remains an area of concern and interest for academic and professional bodies. There is also burgeoning research in the area of moral reasoning and its relevance to the teaching of pharmacy and medicine. Aims: To explore the associations between self-reported ...
Bergeron Maxime - - 2012
The synthesis of monofluoroalkenes using an S(N)2' reaction of lithium amides derived from aromatic amines or lithium thiolates with 3,3-difluoropropenes is reported. This transformation features the use of fluoride as a leaving group.
Duan Xiaochuan - - 2012
In this study, we prepared high-stability hematite mesocrystals by a facile route without polymer additives. In particular, the rhombic hematite mesocrystals exhibit excellent lithium insertion behavior compared to the hematite single-crystals.
Poon Yi-Chieh - - 2012
Abstract Purpose: To evaluate the impact of macular serous retinal detachment (SRD) and its relationship to treatment outcome after primary intravitreal bevacizumab (IVB) injection in patients with branch retinal vein occlusion (BRVO) and macular edema (ME). Methods: Seventy-three patients with ME secondary to BRVO who received primary IVB (2.5 mg/0.1 mL) were ...
Fry R S - - 2012
Copper (Cu) deficiency is a widespread problem in cattle across the United States and breed differences in Cu metabolism may contribute to this issue. Intracellular Cu is tightly regulated by transport and chaperone proteins, and to date these mechanisms have not been elucidated to address breed differences in Cu metabolism, ...
Hii M W - - 2012
BACKGROUND: Oesophageal malignancy is a disease with a poor prognosis. Oesophagectomy is the mainstay of curative treatment but associated with substantial morbidity and mortality. Although mortality rates have improved, the incidence of perioperative morbidity remains high. This study assessed the impact of postoperative morbidity on long-term outcomes. METHODS: A prospective ...
Sontas B H - - 2012
Endometrial adenocarcinoma is described in two young intact female Persian cats presented with haemorrhagic vaginal discharge. The discharge had been present for 3 and 15 days in each case, respectively. On the basis of signalment, history, clinical, laboratory and diagnostic imaging findings a tentative diagnosis of pyometra was made in each ...
Hashizume Naoki - - 2012
Existing standard bioconcentration tests (e.g., the Organization for Economic Cooperation and Development [OECD] test guideline [TG] 305) require large numbers of test animals and resources. The minimized aqueous exposure test is a new approach based on the standard bioconcentration test but allows estimation of bioconcentration factor (BCF) by minimized sampling ...
Delelys Michelle E - - 2012
BACKGROUND: Although platelets (PLTs) are known to express ABH antigens, the extent of expression is different on PLTs compared with red blood cells and the relationship between PLT ABH expression and genotype has not been thoroughly investigated. STUDY DESIGN AND METHODS: We measured blood group H and A antigens on ...
Badran Ismail - - 2012
The kinetics and thermochemistry of the decomposition pathways for 1,3-disilacyclobutane (1,3-DSCB) in the gas phase were studied using the second-order Møller-Plesset (MP2) perturbation theory and coupled cluster methods with single, double and perturbative triple excitations (CCSD(T)). The reactions examined include 2+2 cycloreversion to form two silenes by either a concerted ...
Wu Jin - - 2012
Abstract Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) has been utilized for cancer therapy, but the resistance of cancer cells to TRAIL remains an obstacle. Ether à go-go 1 (Eag1) channel is overexpressed in a variety of cancers and implicated in tumor progression. However, the therapeutic potential of Eag1 in osteosarcoma ...
Song Yantao - - 2012
Silicic acid (H4SiO4) is ubiquitous in natural aquatic systems. Applications of TiO2 in these systems will be influenced by H4SiO4 sorption and oligomerization reactions on the TiO2 surface and this can affect many aspects of TiO2 reactivity. The spatial arrangement of sorption sites on a metal oxide surface can promote ...
Pârvu Alina Elena - - 2012
Aim:To evaluate the effectiveness of subantimicrobial-dose doxycycline (SDD) as an adjunct to scaling and root planing (SRP) treatment against the nitrosative stress of moderate to advanced chronic periodontitis.Methods:Adults with untreated chronic periodontitis (n=174) were randomly administered SRP+SDD (n=87) (20 mg of doxycycline twice daily) or SRP+placebo (n=87) treatment for 3 ...
Van den Berg P J - - 2012
BACKGROUND: A new treatable venous disorder, chronic cerebrospinal venous insufficiency (CCSVI), has been proposed in patients with multiple sclerosis (MS). Its relationship with iron metabolism is suggested, but has not been examined prospectively. METHODS: We performed extra- and transcranial echo colour Doppler (ECD) in 90 patients with MS and 41 ...
Tamada Tsutomu - - 2012
PURPOSE: To compare the conspicuity of hypointense hepatocellular nodules in patients with chronic liver disease on hepatobiliary phase (HP) of gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid (Gd-EOB-DTPA)-enhanced magnetic resonance imaging (MRI) acquired with low to high flip angles (FAs). MATERIALS AND METHODS: A total of 95 patients with chronic liver disease ...
Santos Tiago G - - 2012
Prion protein (PrP(C) ) is a cell surface glycoprotein that is abundantly expressed in nervous system. The elucidation of the PrP(C) interactome network and its significance on neural physiology is crucial to understanding neurodegenerative events associated with prion and Alzheimer's diseases. PrP(C) co-opts stress inducible protein 1/alpha7 nicotinic acetylcholine receptor ...
Uchida Masahiko - - 2012
The clinical course of chronic pancreatitis (CP) worsens with drinking, and pancreatic stellate cells (PSCs) have an important role in the pathogenesis of alcoholic CP. Chemokines recruit inflammatory cells, resulting in chronic pancreatic inflammation. Although serum levels of fractalkine (CX3CL1) are significantly elevated in patients with alcoholic CP, the mechanism ...
Uraguchi Daisuke - - 2012
A vinylog of Michael addition (1,6-addition) of azlactones to δ-substituted dienyl N-acylpyrroles has been developed with virtually complete 1,6-, diastereo-, and enantioselectivities by means of chiral P-spiro triaminoiminophosphorane as a catalyst. This system has been successfully extended to an unprecedented bis-vinylog of Michael addition (1,8-addition) of azlactones to ζ-substituted trienyl ...
Mate C Mathew - - 2012
The radii R of the area wetted by precursor films spreading from small droplets of polymer liquids are found to vary as R ~ t(ν) with ν = 0.32-0.42, in contradiction to the 0.5 exponent indicated in previous studies. The experiments reported here are for three of the same polymer ...
Yu Xiaobin - - 2012
Herba Epimedii, an herb commonly used in East Asian medicine, is commonly used for treatment of impotence, osteoporosis and many inflammatory conditions in traditional Chinese medicine. Recent studies revealed that Herba Epimedii also has anti-tumor or anti-cancer activities, which may possibly be mediated through anti-angiogenesis. This study aims to examine ...
Distler Alfiya - - 2012
OBJECTIVES: Canonical Wnt signalling has recently emerged as a key mediator of fibroblast activation and tissue fibrosis in systemic sclerosis. Here, we investigated tankyrases as novel molecular targets for inhibition of canonical Wnt signalling in fibrotic diseases. METHODS: The antifibrotic effects of the tankyrase inhibitor XAV-939 or of siRNA-mediated knockdown ...
Kileh-Wais M - - 2012
The mule duck, an interspecific hybrid obtained by crossing common duck (Anas Platyrhynchos) females with Muscovy (Cairina moschata) drakes, is widely used for fatty liver production. The purpose of the present study was to detect and map single and pleiotropic QTL that segregate in the common duck species, and influence ...
Balbus John M - - 2012
Global climate change (GCC) is likely to alter the degree of human exposure to pollutants and the response of human populations to these exposures, meaning that risks of pollutants could change in the future. The present study, therefore, explores how GCC might affect the different steps in the pathway from ...
Chambers Gregory - - 2012
This report discusses the diagnosis and treatment of afibrinogenemia in a Chihuahua. Prolongations of prothrombin time (PT), activated partial thromboplastin time (aPTT), and thrombin clotting time (TCT) together with fibrinogen assay results of either no or trace amounts of fibrinogen support a diagnosis of afibrinogenemia. Differential diagnoses include common coagulopathies, ...
Bruschi Giovanni B - - 2012
Abstract Purpose: Since the presence of keratinized gingiva is so important for peri-implant outcome, the aim of this study is to describe a partial thickness flap design to increase the amount of keratinized peri-implant tissue as well as its thickness.Materials and Methods: A total of 131 implants were placed: 103 ...
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