Search Results
Results 351 - 400 of 2432
< 3 4 5 6 7 8 9 10 11 12 13 >
Domingo Victoriano - - 2012
The first synthesis of (+)-myrrhanol C (), an antitumor polypodane-type bicyclic triterpene with inhibitory activity against androgen insensitive prostate cancers, is reported herein (IC(50) 10 μmolar). A key step in our convergent synthesis of (+)-myrrhanol C and related analogues is the employment of a microbial stereo- and regioselective late stage ...
Wang Yang - - 2012
Two kinds of Cu(2)O-ZnO nano-heteroarchitectures were fabricated through a hydrothermal method. By utilizing polyethyleneimine (PEI) as a binding agent, ZnO nanoparticles were uniformly self-assembled onto Cu(2)O micro structures. Photoluminescence (PL), field emission and photocatalytic activities of the composite samples were investigated and compared with those of the pure Cu(2)O samples. ...
Du Liping - - 2012
Reactivation of tumor suppressor genes (TSGs) involved in carcinogenesis by nontoxic bioactive food component represents a promising strategy for cancer chemoprevention. Recently, curcumin has been demonstrated to inhibit a bacterial DNA methyltransferase (M. Sss I) activity, induce global DNA hypomethylation in leukemia cells, and reactivate several hypermethylation silenced genes in ...
Youssefagha Ahmed H - - 2012
Objectives of this study are to determine if a relationship exists between asthma exacerbations among elementary school children in industrialized countries (with climatic seasons) and exposure to daily air pollution with particulate matter, sulfur dioxide, nitrogen dioxide, nitrogen oxides, carbon monoxide, and ozone, when controlled for potential confounders; and, if ...
Yang Sung-Hyun - - 2012
A gram-negative, facultatively anaerobic, rod-shaped (2.04-1.27 µm x 0.95-1.25 µm) and motile marine bacterium, designated as MEBiC06500T was isolated from a sediment collected at the Daebu-Island of the Yellow Sea (126° 41' E, 37° 20' N), Korea. The 16S rRNA gene sequence analysis revealed that strain MEBiC06500T showed high similarity ...
Pepper John R - - 2012
At a recent in-house meeting at the European Association for Cardiothoracic Surgery (EACTS) headquarters in Windsor, the Chairs of the four domains were asked by the President to present their perception of the next 5 years in their respective domains. This review represents a distillation of our discussions on adult ...
Li Xuan - - 2012
Diabetic ophthalmopathy (DO) impairs patients' eyesight and even causes blindness. Here, we investigated the effect of 60% ethanol extract of the rhizome of Anemarrhenae asphodeloides (ERA), which is commonly used in Chinese medicine formulae in treating diabetes, on DO progression. Blood glucose, insulin, advanced glycation end products (AGE), super oxygen ...
Anzo Kenji - - 2012
The data reported in Anal. Chem. 2011, 83, 8152-8157 have been interpreted based on the Gouy-Chapmann (GC) model. While the results for KCl solutions are well explained by the GC model, those for distilled water do not agree with the theory. This is due to the limited applicability of the ...
Riskin Arieh - - 2012
Objective Evaluate the need for urine culture in early neonatal sepsis workup of term and late preterm infants.Study Design Urine culture by suprapubic aspiration or catheter was included in early sepsis evaluations of 173 term and late preterm newborns (mean gestational age 38.6 ± 2.0 weeks) during a 6-month study period. A historic control ...
Singh Kamaljit - - 2012
New, neutral, slightly puckered aromatic meso-substituted tetrathia[22]annulene[2.1.2.1] macrocyclic architectures display p-type semiconductor behaviour and constitute molecular field-effect transistors with high on/off ratios (8.67 × 10(6)) and high mobility (0.23 cm(2) V(-1) s(-1)) in thin films deposited on octadecyltrichlorosilane (OTS) modified SiO(2).
Joshi Sucheta M - - 2012
A substantial minority of children with epilepsy have continued seizures despite adequate trials of standard antiseizure medications. To maximize seizure control and thereby optimize their neurodevelopmental outcomes, alternate nonmedication therapies should be considered for these patients. Dietary therapies, including the ketogenic diet and its variations, have been available for years. ...
Chow J P H - - 2012
Inhibition of cyclin-dependent kinase 1 (CDK1) by phosphorylation is a key regulatory mechanism for both the unperturbed cell cycle and the DNA damage checkpoint. Although both WEE1 and MYT1 can phosphorylate CDK1, little is known about the contribution of MYT1. We found that in contrast to WEE1, MYT1 was not ...
Collu Francesca - - 2012
Basic understanding of the means by which multidrug efflux systems can efficiently recognize and transport drugs constitutes a fundamental step toward development of compounds able to tackle the continuous outbreak of new bacterial strains resistant to traditional antibiotics. We applied a series of computational techniques, from molecular docking to molecular ...
Tajima Naoshi - - 2012
A 65-year-old man was referred to our hospital due to epigastric pain. Abdominal enhanced computed tomography (CT) demonstrated marked dilatation of the main pancreatic duct (MPD) and communication to the gastric and duodenal lumen was suspected. Esophagogastroduodenoscopy (EGD) showed a villous tumor with white mucous discharge in the posterior wall ...
Nishi Mitsumi - - 2012
The reaction of α-thioketones and alkynes in the presence of a rhenium catalyst, [HRe(CO)(4)](n), gave γ-thio-α,β-unsaturated ketones in excellent yields. The alkynes were inserted into the carbon-sulfur bond of the α-thioketones, and isomerization of a double bond provided the products with high regio- and stereoselectivities. This reaction also proceeded in ...
Bailey-Davis Lisa - - 2012
OBJECTIVES:To examine 3-year trends and spatial clustering in the prevalence of obesity among elementary-aged children in Pennsylvania.METHODS:Height and weight were measured for ∼980 000 children between ages 5 and 12 years, corresponding to kindergarten through grade 6 in 3 consecutive school years (2006-2007, 2007-2008, 2008-2009). These data were obtained at the ...
Huxter M J - - 2012
ACCESSIBLE SUMMARY: Throughout recorded history, the mentally ill have been living at the fringes of society, frequently alienated, treated inhumanely, and made as scapegoats for the prevailing societal ills. Australia has seen the number of public psychiatric hospital beds fall from 30 000 in the early 1960's to 8000 as of ...
Cui Jiehu - - 2012
A highly connected 3D metal-organic framework with topology based on Zn(6)O(2) clusters and flexible carboxylate ligands has been synthesized. The obtained Zn-MOF shows solvatochromic behavior for fluorescence sensing of small molecules, gas adsorption properties and exceptional chemical stability and might have applications for separation and detection purposes.
Castillo-Lopez E - - 2012
The objectives of this trial were to determine the rumen undegradable protein (RUP) of dried distillers grains with solubles (DDGS), to compare the estimates of duodenal bacterial crude protein (BCP) flow using diaminopumelic acid (DAPA) or DNA as bacterial markers, and to estimate duodenal protozoal crude protein (PCP) and yeast ...
Hatzikiriakos Savvas G - - 2012
The rheological properties and microstructure of nanocrystalline cellulose (NCC) aqueous suspensions have been investigated at different concentrations. The suspension is isotropic up to 3 wt.%, and phase separates to liquid crystalline and isotropic domains at higher concentrations where the samples exhibit a fingerprint texture and the viscosity profile shows a ...
Yap Desmond Y H - - 2012
Objective. We investigated the long-term outcome of patients with proliferative LN treated with CSs and MMF.Methods. This was a single-centre retrospective study on patients with biopsy-proven class III/IV ± V LN treated with prednisolone and MMF continuously as both early and maintenance immunosuppression.Results. Sixty-five patients were included, and followed for ...
Eng Jimmy K - - 2012
Proteomics research routinely involves identifying peptides and proteins via tandem mass spectrometry sequence database search. Thus the database search engine is an integral tool in many proteomics research groups. Here, we introduce the Comet search engine to the existing landscape of commercial and open source database search tools. Comet is ...
Wang Baojiang - - 2012
We report the cellular properties of a luminescent cyclometalated iridium(III) complex, [Ir(pq)(2) (phen-ITC)](PF(6) ) (Ir-ITC; Hpq=2-phenylquinoline, phen-ITC=5-isothiocyanate-1,10-phenanthroline), that efficiently and specifically labels mitochondria in living mammalian cells. Ir-ITC can be covalently conjugated to its protein targets, and its luminescence survived cell lysis, protein extraction, and gel electrophoresis under denaturing conditions. ...
Seifarth C - - 2012
The efficacy of metformin for the treatment of obesity has been evaluated in few clinical trials with inconclusive results. Moreover, the effectiveness in a real-life outpatient setting has not been tested until today. In this study we aimed to examine the effectiveness of metformin as a weight reducing drug in ...
Choi Hyun Gyu - - 2012
The stem and root barks of Ulmus davidiana var. japonica (Ulmaceae) have been used to treat inflammatory diseases including mastitis, rhinitis, sinusitis, and enteritis. In an ongoing study focused on the discovery of natural anti-inflammatory compounds from natural products, a methanol extract of the stem and root barks of U. ...
Yang Heejung - - 2012
Two ginsenoside derivatives (9-10) along with ten known ginsenosides (1-8 and 11-12) were isolated from BST204 which is crude ginseng extract fermented by enzyme and acid hydrolysis. The two ginsenosides were determined as 12β, 20(S), 25-trihydroxy-dammara-3-O-β-D-glucopyranoside (9) and 12β, 20(R), 25-trihydroxy-dammara-3-O-β-D-glucopyranoside (10). Compounds 1-12 were categorized into steroisomeric pairs differentiated ...
Henry F - - 2012
The aim of the present study was to evaluate the effects of metal contamination on the biological responses of 0-group juvenile European flounder and to assess and compare the quality of four estuarine habitats located in the Eastern English Channel. Fish otolith growth and condition indices (RNA : DNA ratio, Fulton's K ...
Kanwal Sandeep Kumar - - 2012
A retrospective study was done on 48 consecutive patients with clinical diagnosis of post-diphtheritic neuropathy admitted to the paediatric intensive care unit of tertiary care hospital in North India between January 2008 and December 2010 to study the clinical profile of post-diphtheritic neuropathy in children. The case records were reviewed ...
Rankins D L DL - - 2012
Stockering calves in the southern U.S. has been an economically viable enterprise for decades. Historically, the system that yielded the best opportunity for profitability was to purchase light-weight calves (130 kg to 220 kg) in autumn, add 100 to 200 kg of BW gain, and sell them in the spring. ...
Cautela Jennifer - - 2012
AIMS: Whole body imaging with (18)F-fluorodeoxyglucose positron-emission tomography/computed tomography (FDG PET/CT) has proven useful in various infectious diseases. The purpose of this pilot study was to assess the diagnostic yield of FDG PET/CT in patients with cardiac implantable electronic device (CIED) infection.METHODS AND RESULTS: A total of 21 patients with ...
Altiok Ertunc - - 2012
AIMS: Separate analysis of endocardial and epicardial myocardial layer deformation has become possible using strain-encoded cardiovascular magnetic resonance (SENC) and 2D-dimensional speckle tracking echocardiography (Echo). This study evaluated and compared both modalities for the assessment of infarct transmurality as defined by late gadolinium enhancement (LGE) cardiovascular magnetic resonance (CMR). METHODS ...
Hawelek L - - 2012
The structure of a series of activated carbons prepared from anthracite by chemical activation has been studied using wide-angle x-ray scattering, molecular dynamics and Raman spectroscopy. The BET surface areas of the investigated samples are in the range 1500-3430 m(2) g(-1) and the average pore sizes vary from 0.75 to 1.35 nm. The ...
Tanvig M - - 2012
OBJECTIVES: To examine the impact of maternal pregestational body mass index (BMI) and smoking on neonatal abdominal circumference (AC) and weight at birth. To define reference curves for birth AC and weight in offspring of healthy, nonsmoking, normal weight women. DESIGN: Population-based study. SETTING: Data from the Danish Medical Birth ...
Rahman Fazlur - - 2012
OBJECTIVE:Interventions that mitigate drowning risk in developing countries are needed. This study presents the cost-effectiveness of a low-cost, scalable injury and drowning prevention program called Prevention of Child Injuries through Social-Intervention and Education (PRECISE) in Bangladesh.METHODS:Between 2006 and 2010, the 2 components of PRECISE (Anchal, which sequestered children in crèches ...
Ostlind Dan A - - 2012
Abstract This report describes a novel assay for the detection of gastrointestinal anthelmintics using mice infected with Haemonchus contortus and adapted to the 1 animal per group protocol. Mice infected with both H. contortus and Heligmosomoides polygyrus were fed ivermectin-medicated diets for 6 days. A dietary level of 0.09375 ppm ...
Unsgaard-Tøndel Monica - - 2012
BACKGROUND AND PURPOSE: Activation of transversus abdominis and fear avoidance beliefs have both been related to low back pain (LBP). This exploratory study aims to investigate associations between fear avoidance beliefs at baseline and deep abdominal muscle activation after an 8-week period of supervised exercises for chronic LBP. METHODS: A ...
Rakowska M I - - 2012
Addition of activated carbon (AC) to sediments has been proposed as a method to reduce ecotoxicological risks of sediment-bound contaminants. The present study explores the effectiveness of granular AC (GAC) in extracting polycyclic aromatic hydrocarbon (PAH) from highly contaminated sediments. Four candidate GAC materials were screened in terms of PAH ...
Qian Hang - - 2012
This communication reports a novel intermolecular interaction for structural DNA nanotechnology.
Jo Dong Hyun - - 2012
Abstract Nanoparticles can be used for the treatment of various retinal diseases. Due to small sizes, they can improve bioavailability of therapeutic agents and pass through biological barriers of the eye, such as the cornea, conjunctiva, sclera, and even more, blood-retinal barriers. Another important characteristic of nanoparticles is the ability ...
Kranzler Henry R - - 2012
We previously reported moderating effects of age of onset of alcohol dependence (AD) and a functional polymorphism (5-HTTLPR) in the gene encoding the serotonin transporter protein in a sample of 134 individuals participating in a 12-week, placebo-controlled trial of sertraline. To understand more fully the effects seen in that study, ...
Karagiannis Michael H - - 2012
The objective of this study was to compare two portable lactate analyzers for testing canine patients in a clinical setting with a previously accepted methodology for measuring plasma lactate. Between Jan 1, 2005 and Jun 1, 2006, all samples were analyzed using two different portable analyzers (devices A and B), ...
Hu Xiao Liang - - 2012
Solar-driven water splitting is a key photochemical reaction that underpins the feasible and sustainable production of solar fuels. An amorphous cobalt-phosphate catalyst (Co-Pi) based on earth-abundant elements has been recently reported to efficiently promote water oxidation to protons and dioxygen, a main bottleneck for the overall process. The structure of ...
Bogle Brittany - - 2012
AIM: We sought to quantify knowledge and attitudes regarding automated external defibrillators (AEDs) and cardiopulmonary resuscitation (CPR) among university students. We also aimed to determine awareness of the location of an actual AED on campus. METHODS: We performed an online survey of undergraduate and graduate students at a mid-sized, private ...
Sheu Shih-Yi - - 2012
A bacterial strain, designated CMJ-5T, was isolated from a freshwater shrimp culture pond in Taiwan and characterized using a polyphasic taxonomy approach. Cells of strain CMJ-5T were Gram-staining-negative, strictly aerobic, non-motile, yellow-pigmented rods surrounded by a thick capsule. Growth occurred at 20-35 oC (optimum, 30°C), at pH 6.5-8.0 (optimum, pH ...
Czerny Martin - - 2012
At least every ten years, each specialty should reflect upon its past, its present and its future, in order to be able to reconfirm the direction in which it is headed, to adopt suggestions from inside and outside and, consequently, to improve. As such, the aim of this manuscript is ...
Ilica A Turan - - 2012
PURPOSE: To evaluate the role of diffusion-weighted magnetic resonance imaging (DWMRI) in differentiating benign and malignant thyroid nodules using a 3 Tesla (T) MRI scanner. MATERIALS AND METHODS: Twenty-eight nodules in 25 patients and 14 healthy control cases were included in the study. DWMRI was acquired with 6 b values ...
Alslaibi Tamer M - - 2012
Landfills are a source of groundwater pollution in Gaza Strip. This study focused on Deir Al Balah landfill, which is a unique sanitary landfill site in Gaza Strip (i.e. it has a lining system and a leachate recirculation system). The objective of this article is to assess the generated leachate ...
Brown Tanya M - - 2012
Although the presence and distribution of polychlorinated biphenyls (PCBs) in Arctic marine environments has been well documented, the implications for the health of biota are poorly understood. In the present study, multiple lines of evidence, including site-specific effects data, were used to assess PCB-related risks to marine biota at a ...
Krieter Detlef H - - 2012
The estrogenic endocrine-disrupting substance bisphenol A (BPA) is extensively used as a starting material for a variety of consumer plastic products including dialyzer materials. The present study was performed to explore plasma BPA levels in patients with impaired renal function and to investigate if dialyzers differing in elutable BPA influence ...
Sinclair Lisa Bundara - - 2012
This article describes use of the International Classification of Functioning, Disability and Health (ICF) as a tool for strategic planning. The ICF is the international classification system for factors that influence health, including Body Structures, Body Functions, Activities and Participation and Environmental Factors. An overview of strategic planning and the ...
< 3 4 5 6 7 8 9 10 11 12 13 >