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Results 251 - 300 of 2469
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Lebeau Richard T - - 2012
In preparation for DSM-5's planned inclusion of dimensional assessments of psychopathology as a complement to traditional categorical diagnoses, we developed brief self-rated scales for anxiety disorders that are consistent in content and structure. In the present paper, we discuss the creation of the scales and examine their psychometric properties and ...
Pongratz Georg - - 2012
The peripheral nervous system takes an active part in inflammatory processes by regulating effector cell function and reallocation of energy to the immune system. During acute inflammation, rapid neuronal reorganization and change of activity takes place. The hallmarks of this process are an increase in systemic sympathetic activity, a decrease ...
Lambert Carole - - 2012
The interaction between Vitis vinifera and trunk disease fungi requires better understanding. We studied the role of phenolics as possible plant defense compounds in this context. The impact of 24 grapevine phenolic compounds was determined on 6 major wood decay fungi by an in vitro agar plate assay. Hydroxystilbenoids, especially ...
Alrehaily L M - - 2012
The formation of chromium oxide nanoparticles by gamma radiolysis of Cr(VI) (CrO(4)(2-) or Cr(2)O(7)(2-)) solutions was investigated as a function of pH and initial Cr(VI) concentration by measuring [Cr(VI)], the particle concentration ([Cr(III)(col)]) and [H(2)], and by characterizing the particles using TEM, Raman, FTIR and XPS. The results show that ...
Fei Jinbo - - 2012
Responsive nanohelices can be self-assembled via asymmetric coordination bonding between AgNO(3) and melamine. Silver nanochains composed of nanoparticles can be synthesized simply by photo-reduction of the above complex.
Mathew A - - 2012
Study design:Cross-sectional survey.Objective:To compare the relationship between engagement in occupational activities and pressure ulcer (PU) development in persons with spinal cord injury (SCI).Study setting:Tertiary care university teaching hospital, Tamil Nadu, India.Method:One hundred and eight persons with SCI who were previously rehabilitated from our center were included in the study. A ...
Murdock Courtney C CC Merkle Laboratory, Center for Infectious Disease Dynamics, Department of Entomology, Pennsylvania State University, Orchard Road, University Park, State College, Pennsylvania 16802, USA. - - 2012
Recent ecological research has revealed that environmental factors can strongly affect insect immunity and influence the outcome of host-parasite interactions. To date, however, most studies examining immune function in mosquitoes have ignored environmental variability. We argue that one such environmental variable, temperature, influences both vector immunity and the parasite itself. ...
Guilcher S J T - - 2012
Study design:Retrospective cohort with linkage of administrative data sets.Objectives:To describe the patterns (for example, number of visits by year post-injury) and characteristics of the emergency department (ED) visits (for example, acuity level, timing of visits, reasons for visits) made by persons with traumatic spinal cord injury (TSCI) over a 6-year ...
Viswanathan Deepa - - 2012
BACKGROUND: Collagen crosslinking has been reported to be effective in treating progressive keratoconus and this study aims to evaluate the long term efficacy of this procedure. DESIGN: Prospective longitudinal interventional study of patients with progressive keratoconus who underwent crosslinking in a tertiary referral hospital. PARTICIPANTS: Thirty five patients (fifty one ...
Green Jennifer Greif JG School of Education, Boston University, Boston, MA, - - 2012
We examine differential validity of the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV) diagnoses assessed by the fully-structured Composite International Diagnostic Interview Version 3.0 (CIDI) among Latino, non-Latino Black, and non-Latino White adolescents in comparison to gold standard diagnoses derived from the Schedule for Affective Disorders and ...
Rolland-Cachera M F - - 2012
Background:There is overwhelming evidence that experiences during early life could have long-term health consequences. However, the role of early nutrition in programming obesity and leptin resistance is still poorly understood.Objective:We aimed at determining whether nutritional intakes in early life are associated with body composition and hormonal status at 20 years.Subjects:Healthy ...
Luqmani Raashid - - 2012
A fundamental change in management of antineutrophil cytoplasmic antibody-associated vasculitis in the past 10 years is the early focussed use of aggressive immunosuppression, using regimens comprised of widely available medications. Using a clinical framework to quantify morbidity, we can induce remission in most patients within 3-6 months using glucocorticoids plus ...
Jiang Jing J Group of Epigenetic Reprogramming, State Key Laboratory of Cell Biology, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, - - 2013
Induced pluripotent stem (iPS) cells generated using Yamanaka factors have great potential for use in autologous cell therapy. However, genomic abnormalities exist in human iPS cells, and most mouse iPS cells are not fully pluripotent, as evaluated by the tetraploid complementation assay (TCA); this is most likely associated with the ...
Piao Yunxian - - 2012
Molecular beacons (MBs) have shown fascinating applications in many biological fields. However, exploration of cost-effective, sensitive, stable and efficient MB for in situ live cell- based assay has still room for improvement. In this regards, we have developed a novel MB which bears a spherical graphite nanoparticle (GN) as a ...
Hernández-Ainsa Silvia - - 2012
We report a simple and efficient way to accomplish the chemical modification of glass nanopores by means of lipid self-assembly. Lipid coating improves the success rate of these glass nanopores as biosensors to detect λ-DNA.
Geyh S - - 2012
Study design:An international cross-sectional study.Objective:To examine the quality of life (QoL) of people with spinal cord injury (SCI) across six countries worldwide, controlling for socio-demographic and lesion-related sample characteristics and using a cross-culturally valid assessment.Methods:Data from 243 persons with SCI from Australia, Brazil, Canada, Israel, South Africa and the United ...
Rametta R R Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milano, - - 2013
The aim of this study was to evaluate whether dysregulation of molecules involved in FOXO1-dependent insulin signaling in the liver is associated with de novo lipogenesis (DNL) and altered lipid metabolism in severely obese subjects. Observational retrospective study. We considered 71 obese subjects (age 20-68 years; body mass index (BMI)>40 kg m(-2) ...
Aquino Priscila F - - 2012
A strategy for treating cancer is to surgically remove the tumor together with a portion of apparently healthy tissue surrounding it, the so-called "resection margin", to minimize recurrence. Here, we investigate whether the proteomic profiles from biopsies of gastric cancer resection margins are indeed more similar to those from healthy ...
Turner Nicholas C - - 2012
ABSTRACT: A recent prospective clinical trial provides further evidence that breast cancers arising in germline BRCA1 mutation carriers are highly sensitive to cisplatin chemotherapy. The potential significance of these data for the management of patients with BRCA1-related and BRCA2-related breast cancer is discussed.
Booth Sarah L SL Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA. - - 2013
Increasing evidence supports an association between the skeleton and energy metabolism. These interactions are mediated by a variety of hormones, cytokines and nutrients. Here, the evidence for a role of osteocalcin in the regulation of glucose metabolism in humans is reviewed. Osteocalcin is a bone matrix protein that regulates hydroxyapatite ...
Win-Shwe Tin-Tin - - 2012
Previously, we demonstrated that maternal exposure to phthalates enhances atopic dermatitis in male mouse offspring. However, whether phthalate exposure affects neuroimmune biomarkers in allergic mice has not yet been studied. Di-(2-ethylhexyl) phthalate (DEHP) and di-isononyl phthalate (DINP) are environmental chemicals that are commonly used as plasticizers. This study was designed ...
Li Yibao - - 2012
We investigate the influence of temperature on the self-assembly of 2,6,11-tricarboxydecyloxy-3,7,10-triundecyloxy triphenylene (asym-TTT) adsorbed on HOPG using scanning tunneling microscopy (STM) at the liquid/solid interface. We show that the packing structures of 2D self-assembled asym-TTT can be precisely tuned by adjusting the substrate temperature. The temperature change from 20 °C ...
Nabika Hideki - - 2012
The ability to control chemical wave propagation dynamics could stimulate the science and technology of artificial and biological spatiotemporal oscillating phenomena. In contrast to the conventional chemical approaches to control the wave front dynamics, here we report a physical approach to tune the propagation dynamics under the same chemical conditions. ...
Xu Weixin - - 2012
The structural characterization of amyloid fibers is one of the most investigated areas in structural biology. Recently, protofibril models for amylin, i.e., the 37-residue human islet amyloid polypeptide or hIAPP were suggested by two groups based on NMR (Luca et al., Biochemistry 2007;46:13505-13522) and X-ray (Wiltzius et al., Protein Sci ...
Matsui Shoko - - 2012
SUMMARY AT A GLANCE: The clinicoradiological and pathological features of IgG4-related lung disease were assessed. Clinically, this disease is silent, although radiological and pathological examinations showed that it involves lymphatic routes, with spread observed on imaging and infiltration on pathological examination. Clinicoradiological and pathological correlation is necessary for the diagnosis ...
Ruths Sabine - - 2012
BACKGROUND: Psychotropic drugs are extensively prescribed for the treatment of neuropsychiatric symptoms, despite modest efficacy and severe side effects. AIMS: We examined trends in psychotropic drug prescribing in Norwegian nursing homes from 1997 to 2009, in order to gain insight in practice development. METHODS: The study is a secondary data ...
He Jun - - 2012
Microcystin-LR (MCLR), a potent hepatotoxin, is causing increasing risk to public health. Although liver is the main target organ of MCLR, the metabolic profiling of liver in response to MCLR in vivo remains unknown. Here, we comprehensively analyzed the metabolic change of liver and ileal flushes in rat orally gavaged ...
Arfin T - - 2012
A new crystalline organic-inorganic nano-composite nylon-6,6 nickel phosphate membrane was synthesised subsequent to which (a) the physico-chemical characteristics of the membrane were evaluated employing FTIR, SEM, EDX, TEM, XRD and porosity measurements, and (b) membrane potential measurements were conducted employing different concentrations (0.0001 ≤ c (M) ≤ 1) of KCl, ...
Hsieh Ya-Lin - - 2012
This study investigated the relationship between mothers' daily occupational experiences of productivity, restoration and pleasure with their subjective well-being (SWB) and with their child's developmental skills. Forty caregivers parenting young children with autism spectrum disorders served as a convenience sample in this study. Participants rated their occupational experience in a ...
Söderberg M M - - 2012
The widely used antipsychotic drug, olanzapine (OLA) shows large interindividual variability in metabolic clearance. Although the role of the enzymes CYP1A2, CYP2D6 and UGT1A4 has been extensively explored, little is known about the in vivo role of flavin-containing monooxygenases (FMOs) catalyzing the N-oxidation of OLA in vitro. We investigated the ...
Chang Bor Kae - - 2012
Carbon dioxide adsorption sites within the flexible metal-organic framework (MOF) zinc 1,2-bis(4-pyridyl)ethane tetrafluoroterephthalate (Znbpetpa) were investigated using density functional theory (DFT) and canonical Monte Carlo (MC) calculations. Two types of sites with different heats of adsorption were found by using DFT and confirmed by the MC results. Expansion of the ...
Krisa L - - 2012
Study design:A prospective repeated measures multicenter study to determine reliability at individual spinal levels when applied to young persons with spinal cord injury (SCI).Objectives:To evaluate intra- and inter-rater agreement of repeated motor and sensory scores at individual spinal levels.Setting:Shriners Hospitals for Children-Philadelphia and Chicago, USAMethods:A total 189 youth with complete ...
Thompson Stephanie - - 2012
Background: Computer-based clinical decision support aims to improve the quality of patient care. The utility of decision support for improving blood pressure control in hemodialysis patients is unknown. Methods: This was a nonrandomized controlled trial of adult patients receiving chronic in-center hemodialysis during the period of April 1, 2005, to ...
Sibarita Jean-Baptiste JB University of Bordeaux, Interdisciplinary Institute for Neuroscience, CNRS, Bordeaux, France. - - 2012
The second 'Single Molecule Localization Microscopy' symposium was held in August 2012 at the École Polytechnique Fédérale de Lausanne in Switzerland. During two and a half days, around 100 researchers from across the globe, and in disciplines spanning physics, biology, chemistry and computer science, gathered to discuss the developments in ...
Castiello Luciano L Cell Processing Section, Department of Transfusion Medicine, Clinical Center, National Institutes of Health, Bethesda, Maryland 20892, - - 2013
Cell-based immunotherapies are among the most promising approaches for developing effective and targeted immune response. However, their clinical usefulness and the evaluation of their efficacy rely heavily on complex quality control assessment. Therefore, rapid systematic methods are urgently needed for the in-depth characterization of relevant factors affecting newly developed cell ...
Kadappu Subhashini - - 2012
BACKGROUND: This paper reports on the aetiology and outcome of childhood open and closed globe eye injuries presenting to the Children's Hospital at Westmead, Sydney, Australia from January 2000 to December 2008. DESIGN: Hospital-based retrospective study PARTICIPANTS: Two hundred and three cases of childhood eye injuries identified in a 9 ...
McKay Dianne - - 2012
The world population is rapidly growing and ageing at a pace that is projected to continue for at least three decades. This shift towards an older populace has invariably increased the number of individuals with diseases related to ageing, such as chronic kidney disease. The increase in chronic kidney disease ...
Salter Susannah J - - 2012
This month's Genome Watch highlights new insights into the use of bacteria in industrial processes such as electricity generation and bioremediation.
Valette M - - 2012
Melanocortin-4 receptor (MC4R) mutations are the most common known cause of monogenic obesity and an important contributor to polygenic obesity. MC4R mutations with partial or total loss of function, as well as the variant rs17782313 mapped near MC4R, are positively associated with obesity. MC4R is involved in the leptin-melanocortin signalling ...
Schoepke Nicole - - 2012
This randomized, double-blind, placebo-controlled crossover study compared inhibition by one 5 mg dose of levocetirizine with two 60 mg doses of fexofenadine separated by 12 h of histamine-induced wheal and flare responses in 9 Caucasian and 9 Japanese healthy male volunteers. Levocetirizine was more inhibitory than fexofenadine on wheal, flare ...
Chen Shuyi S Stowers Institute for Medical Research, 1000 East 50th Street, Kansas City, MO 64110, USA. - - 2013
The optic fissure (OF) is a transient opening on the ventral side of the developing vertebrate eye that closes before nearly all retinal progenitor cell differentiation has occurred. Failure to close the OF results in coloboma, a congenital disease that is a major cause of childhood blindness. Although human genetic ...
Pan Ling - - 2012
Ketene dithioacetals are versatile intermediates in organic synthesis. Extensive research, since the last decade, has given rise to new prospects in their chemistry. The objective of this review is twofold: first, to highlight the new prospects in the chemistry of functionalized ketene dithioacetals, and second, to provide an intrinsic link ...
Waters M - - 2012
Background:The ratio of the second to the fourth digit (2D:4D ratio) is a sexually dimorphic trait established in utero that differs between ethnic groups. It is associated with prenatal androgen exposure, and studies have evaluated the ratio as a marker for certain traits and disease states known to be associated ...
Arcadi Antonio - - 2012
The scope and the generality of gold versus silver catalyzed intramolecular hydroarylation reactions of 3-[(3-arylprop-2-ynyl)oxy]benzene derivatives in terms of rings substitution were investigated. Only products deriving from 6-endo cyclization were exclusively formed. The features of substituents had a considerable effect on the reaction outcome in the presence of silver catalysis, ...
Leusen Jeanette H W JH Immunotherapy Laboratory, University Medical Center, Utrecht, the Netherlands. - - 2012
The 'Immunoreceptors' meeting took place in July 2012 in beautiful Snowmass Village in Colorado, USA. At an altitude of more than two kilometres, researchers and clinicians discussed the molecular aspects of immunoreceptors, ranging from B- and T-cell receptors, to complement and Fc receptors.
Venkatesh Swaminathan S Stowers Institute for Medical Research, 1000 E. 50th Street, Kansas City, MO 64110, - - 2013
An abundance of long non-coding RNA (lncRNA) present in most species from yeast to human are involved in transcriptional regulation, dosage compensation and imprinting. This underscores the importance of lncRNA as functional RNA despite the fact that they do not produce proteins. Two recent papers in Cell have demonstrated that ...
- - 2012
The following articles are being highlighted as part of Circulation's Topic Review series. This series will summarize the most important manuscripts, as selected by the editors, published in Circulation and the Circulation subspecialty journals. The studies included in this article represent the most read manuscripts published on the topic of ...
Flook Nigel W - - 2013
High-quality data regarding the efficacy of acid-suppressive treatment for unexplained chest pain are lacking. The aim of this study was to evaluate the efficacy of esomeprazole in primary-care treatment of patients with unexplained chest pain stratified for frequency of reflux/regurgitation symptoms. Patients with a ≥ 2-week history of unexplained chest ...
Zhou Xiuwen - - 2012
The absorption spectrum of fluorenone in zeolite L is calculated from first-principles simulations. The broadening of each band is obtained from the explicit treatment of the interactions between the chromophore and its environment in the statistical ensemble. The comparison between the simulated and measured spectra reveals the main factors affecting ...
Stevanovic Stephane - - 2012
The absorption of carbon dioxide by the pure ionic liquids 1-ethyl-3-methylimidazolium acetate ([C1C2Im][OAc]) and 1-butyl-3-methylimidazolium acetate ([C1C4Im][OAc]) was studied experimentally from 303 K to 343 K. As expected, the mole fraction of absorbed carbon dioxide is high (0.16 at 303 K and 5.5 kPa and 0.19 at 303 K and ...
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